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KVPELTGDHSLARNNLSQHPIPPGSLIWKYWGRLDVSFFGNAAMGPIAGAWPQMAQATAGSVLFTGDNSL RARAKIYKERTRRSHEYIYSTVYDAPEDAKKYGLKIRNMHKPVKGKLKDGTFNALNAETFYFAHVTFFYY LLIRVVEQLHFDGSMPRAMKEQIFEESKEWYSLLGVDDSAQPGTYDDFERYLENIERNKLVRSQVTELML EQFMERRVAPRWWPPVMKKYVWPWLAARRQIVVNCYPAHVKDLFGLEWTPEDEDMSRRFMHMYRRLSAVV ERFVPLRLLYLPIAARGFEREGIDPRDVTLESAQRTLRESRARWAAQKCSEGKEEVPTPG*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. smegmatis MC2 155 | MSMEG_3374 | - | - | 100% (341) | hypothetical protein MSMEG_3374 |
| M. smegmatis MC2 155 | MSMEG_3781 | - | 9e-26 | 31.25% (256) | hypothetical protein MSMEG_3781 |
| M. smegmatis MC2 155 | MSMEG_5767 | - | 3e-19 | 27.24% (312) | hypothetical protein MSMEG_5767 |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb1672c | - | 2e-28 | 31.50% (254) | hypothetical protein Mb1672c |
| M. gilvum PYR-GCK | Mflv_3536 | - | 7e-29 | 32.15% (311) | hypothetical protein Mflv_3536 |
| M. tuberculosis H37Rv | Rv1645c | - | 2e-28 | 31.50% (254) | hypothetical protein Rv1645c |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | MAB_3263c | - | 1e-148 | 73.25% (329) | hypothetical protein MAB_3263c |
| M. marinum M | MMAR_0288 | - | 2e-35 | 34.15% (287) | hypothetical protein MMAR_0288 |
| M. avium 104 | MAV_2862 | - | 1e-153 | 74.25% (334) | hypothetical protein MAV_2862 |
| M. thermoresistible (build 8) | TH_1589 | - | 3e-25 | 29.24% (301) | CONSERVED HYPOTHETICAL PROTEIN |
| M. ulcerans Agy99 | MUL_4835 | - | 2e-32 | 33.10% (287) | hypothetical protein MUL_4835 |
| M. vanbaalenii PYR-1 | Mvan_3322 | - | 7e-29 | 30.87% (311) | hypothetical protein Mvan_3322 |
CLUSTAL 2.0.9 multiple sequence alignment
Mflv_3536|M.gilvum_PYR-GCK --------------------------MANDSLSPEGSETPEGAA------
Mvan_3322|M.vanbaalenii_PYR-1 --------------------------MADS--------------------
TH_1589|M.thermoresistible__bu ---------------VTEQLGLCEVPMAAKSTTSRNRRSDAGGAGAQDFP
Mb1672c|M.bovis_AF2122/97 --------------------------MTVASRTS----------------
Rv1645c|M.tuberculosis_H37Rv --------------------------MTVASRTS----------------
MMAR_0288|M.marinum_M --------------------------MATELTAGVDFDTGVREALP----
MUL_4835|M.ulcerans_Agy99 --------------------------MATELTAGVDFDTGVREALP----
MAB_3263c|M.abscessus_ATCC_199 MSKWRGIGKREEFDVVVRGIKAFKKIMQTTFDPELVIPEEVRVTEFTG--
MAV_2862|M.avium_104 --------------MAVRGIRALKKIMQTTFDPELVVPDEARVTEFTG--
MSMEG_3374|M.smegmatis_MC2_155 ----------------------------------------MKVPELTG--
Mflv_3536|M.gilvum_PYR-GCK --------QPQAPG----AFPLGPDSLTWKYFGDVRTGILGVWIGA-IQN
Mvan_3322|M.vanbaalenii_PYR-1 ---------PPAAG----ADPLGPDSLTWKYFGDVRTGMLGVWVGA-IQN
TH_1589|M.thermoresistible__bu ADTPRPEPRPGPSGTTPAAQPLGPDSLTWKYFGDLRTGLLGVWIGA-IQN
Mb1672c|M.bovis_AF2122/97 ------------------ADPLGPDSLTWKYFGDLRTGMMGVWIGA-IQN
Rv1645c|M.tuberculosis_H37Rv ------------------ADPLGPDSLTWKYFGDLRTGMMGVWIGA-IQN
MMAR_0288|M.marinum_M ------MPIDRPVDDEIVAQRLGPTSLIWKFYGDVRTQLFGFQRAAGTEN
MUL_4835|M.ulcerans_Agy99 ------MPIDRPVDDEIVAQRLGPTSLIWKFYGDVRTQLFGFQRAAGTEN
MAB_3263c|M.abscessus_ATCC_199 --------DNSLSRKDLCQHPIPADSLIWKYWGRFDVMYFGSGVLGPIAG
MAV_2862|M.avium_104 --------DNSLSRKDLSQHPIPPGSLTWKYWGRLDVIFFGSGVVGTIAG
MSMEG_3374|M.smegmatis_MC2_155 --------DHSLARNNLSQHPIPPGSLIWKYWGRLDVSFFGNAAMGPIAG
: . ** **::* . . :* . .
Mflv_3536|M.gilvum_PYR-GCK MYPQLGAGVEDHSILMREP---------LQRVARSVYPIMGVVYDGDR-A
Mvan_3322|M.vanbaalenii_PYR-1 MYPQLGAGVEDHSILLREP---------LQRVARSVYPIMGVVYDGDR-A
TH_1589|M.thermoresistible__bu MYPELGAGVTDHSIVLQEP---------LQRVARSVYPIMGVVYDGDR-A
Mb1672c|M.bovis_AF2122/97 MYPELGAGVEEHSILLREP---------LQRVARSVYPIMGVVYDGDR-A
Rv1645c|M.tuberculosis_H37Rv MYPELGAGVEEHSILLREP---------LQRVARSVYPIMGVVYDGDR-A
MMAR_0288|M.marinum_M CIEQLGQGVLDHSVVFSDT---------LGRAKRTGPPLMRTVYSED--P
MUL_4835|M.ulcerans_Agy99 CIEQLGQGVLDHSVVFSDT---------LGRAKRTGSPLMRPVYSED--P
MAB_3263c|M.abscessus_ATCC_199 AWPQMGRGTAGSVLFNGDSSFRARAKIYKKRRQRSREYIYGSVYDPPEDA
MAV_2862|M.avium_104 AWPQMAKATSSSVLFTGDSSFGARSKIYKVRRQRSREYIYGTVYDAPEDA
MSMEG_3374|M.smegmatis_MC2_155 AWPQMAQATAGSVLFTGDNSLRARAKIYKERTRRSHEYIYSTVYDAPEDA
::. .. :. : * *: : **. .
Mflv_3536|M.gilvum_PYR-GCK AQTGAQIRGYHKTIKGVDADGRRYHALNPETFYWAHATFFMLIIK---TA
Mvan_3322|M.vanbaalenii_PYR-1 AQTGAQIRGFHKTIKGADSDGRRYHALNPETFYWAHATFFMLIIK---TA
TH_1589|M.thermoresistible__bu PLTGAQIKSYHRDIKGVDAAGRRYHALNPETFYWAHATFFMLILK---TA
Mb1672c|M.bovis_AF2122/97 AQTGQQIKGYHRTIKGVDAEGRRYHALNPDTFYWAHATFFMLVIK---VA
Rv1645c|M.tuberculosis_H37Rv AQTGQQIKGYHRTIKGVDAEGRRYHALNPDTFYWAHATFFMLVIK---VA
MMAR_0288|M.marinum_M HGWGRTVRDFHKPIKGTIGDGSRYHALNPELFYWAHATFVDQILY---NT
MUL_4835|M.ulcerans_Agy99 HGWGRTVRDFHKPIKGTIGDGSRYHALNPELFYWAHATFVDQILY---NT
MAB_3263c|M.abscessus_ATCC_199 KKYGLKTRNMHKSVKGTLQDG-TFHALNAETFYFAHVTFFYHHLMVVTER
MAV_2862|M.avium_104 KKYGLKTRNMHKSIKGTLQDG-TFHALNADTFYFGHVTFFYHLLLKVVEQ
MSMEG_3374|M.smegmatis_MC2_155 KKYGLKIRNMHKPVKGKLKDG-TFNALNAETFYFAHVTFFYYLLIRVVEQ
* :. *: :** * ::***.: **:.*.**. :
Mflv_3536|M.gilvum_PYR-GCK EYFCGGLTEAEKEQLFDEHVQWYRMYGMSMAPVPESWQAFCEYWDRKCRE
Mvan_3322|M.vanbaalenii_PYR-1 EYFCGGLTEAEKRQLFDEHVQWYRMYGMSMQPVPESWEAFCEYWDRKCRE
TH_1589|M.thermoresistible__bu EYFCGGLTEAEKHQLFDEHVRWYRMYGMSMRPVPRTWEEFCEYWDRTCRE
Mb1672c|M.bovis_AF2122/97 EYFCGGLTEAEKHQLFEEHVRWYRMYGMSMRPVPKSWEDFQDYWDRVCRD
Rv1645c|M.tuberculosis_H37Rv EYFCGGLTEAEKHQLFEEHVRWYRMYGMSMRPVPKSWEDFQDYWDRVCRD
MMAR_0288|M.marinum_M DTFIRRLSRAEKEQIFEESKIWYGLYGVSDRSQPQTYDEFVAYWDGMLDR
MUL_4835|M.ulcerans_Agy99 DTFIRRLSRAEKEQIFEESKIWYGLYGVSDRSQPQTYDEFVAYWDGMLDR
MAB_3263c|M.abscessus_ATCC_199 LHFDGDMPRAVKEQIFEESKEWYSMWGVDDGPQPDTYDDFERYLENVERN
MAV_2862|M.avium_104 LYFDGAMPRAMKEQIFEESKEWYSMWGVDDSPQPATYDDFERYLDNIERN
MSMEG_3374|M.smegmatis_MC2_155 LHFDGSMPRAMKEQIFEESKEWYSLLGVDDSAQPGTYDDFERYLENIERN
* :..* *.*:*:* ** : *:. . * ::: * * :
Mflv_3536|M.gilvum_PYR-GCK ELEINSATLDILSMRIPKPWFVLMPTPVWDQMFKPMIGAQRWIAAGVFDP
Mvan_3322|M.vanbaalenii_PYR-1 ELEINKATLDIFSMRIPKPWFVMMPTPLWDQIFKPMVGAQRWIAAGVFDP
TH_1589|M.thermoresistible__bu QLEINQAALDILHIRIPKPWFVLMPTPVWDQLFRPLLAGQRWVAAGVFEP
Mb1672c|M.bovis_AF2122/97 KLEINQATVDILQMRIPKPRFVLMPTPIWDQLFKPLIAGQRWIAAGLFDP
Rv1645c|M.tuberculosis_H37Rv KLEINQATVDILQMRIPKPRFVLMPTPIWDQLFKPLIAGQRWIAAGLFDP
MMAR_0288|M.marinum_M FVPHKTVLYGTGYLRKGIPGPRKLPALIWRILSAPLNAYARLVIVGTLPP
MUL_4835|M.ulcerans_Agy99 FVPHKTVLYGTGYLRKGIPGPRKLPALIWRILSAPLNAYARLVIVGTLPP
MAB_3263c|M.abscessus_ATCC_199 HLVRSQVTQLMLEQFMERRLAPRWWPTAMKKFVWPWLVGRRQVVVSSYPP
MAV_2862|M.avium_104 HLVNSQVTQVMLEQFMERRVPPRWWPPVMKKFVWPWVAGRRQVVVNSFPP
MSMEG_3374|M.smegmatis_MC2_155 KLVRSQVTELMLEQFMERRVAPRWWPPVMKKYVWPWLAARRQIVVNCYPA
: . . . * * : .. .
Mflv_3536|M.gilvum_PYR-GCK VVRERAGMRWTPGDEIVLRLFGKMVELAFVAVPDEIRLHPRAVAAYRRAE
Mvan_3322|M.vanbaalenii_PYR-1 VVRERAGMRWTPGDEIVLRLFGKLVELAFLAVPDEIRLHPRAVAAYRRAE
TH_1589|M.thermoresistible__bu VLREKAGMRWTPGDEVLLRLFGKLVELAFVAVPDEIRLHPRALSAYRRAS
Mb1672c|M.bovis_AF2122/97 AVREKAGMHWTPGDEVLLRVFGKVVELAFLAVPDEIRLHPRALAAYRRAA
Rv1645c|M.tuberculosis_H37Rv AVREKAGMHWTPGDEVLLRVFGKVVELAFLAVPDEIRLHPRALAAYRRAA
MMAR_0288|M.marinum_M QMREVCDLDWNAKKERRFQRFAALIR-GLNPVLGRLPVRLIYLPWAAQAW
MUL_4835|M.ulcerans_Agy99 QMREVCDLDWNAKKERRFQRSAALIR-GLNPVLGRLPVRLIDLPWAAQAR
MAB_3263c|M.abscessus_ATCC_199 HVRELFALEWTPEDEEMLRRFMDMYRRCYAVLERLLPVKCFYLPTAVRGF
MAV_2862|M.avium_104 HVQELFNLEWTPEDEEIARRFMRMYRRLYAILERVVPLKFLYLPIAVEGF
MSMEG_3374|M.smegmatis_MC2_155 HVKDLFGLEWTPEDEDMSRRFMHMYRRLSAVVERFVPLRLLYLPIAARGF
::: : *.. .* : : . : : :: :. ..
Mflv_3536|M.gilvum_PYR-GCK GKVPADAPLVEAPAFMAPPRDRRSMPMHYLPPR------------KTLLD
Mvan_3322|M.vanbaalenii_PYR-1 GKIPADAPLVEAPAFMAPPRDRRHMPMHYLPPQ------------KSLLD
TH_1589|M.thermoresistible__bu GRIPADAPLVEAPAFTGPPGDRRGLPMHYVPRR------------RSLIE
Mb1672c|M.bovis_AF2122/97 GRTRHDAPLVQAPGFMAPPRDRQGLPMHYFPPRSHRFTRSALDPAKALME
Rv1645c|M.tuberculosis_H37Rv GRTRHDAPLVQAPGFMAPPRDRQGLPMHYFPPRSHRFTRSALDPAKALME
MMAR_0288|M.marinum_M TRSGVDPRRLHRRAVST---------------------------------
MUL_4835|M.ulcerans_Agy99 TRSGVDPRRLHRRAVST---------------------------------
MAB_3263c|M.abscessus_ATCC_199 EREGIDPRNITLESARQALRDNRAR--------------------RAPRK
MAV_2862|M.avium_104 KREGVDPRKITLESAQQALRENRAR--------------------RAARE
MSMEG_3374|M.smegmatis_MC2_155 EREGIDPRDVTLESAQRTLRESRAR--------------------WAAQK
: *. : .
Mflv_3536|M.gilvum_PYR-GCK RVGSLVHSTFSLAGRRPARGTGKAA
Mvan_3322|M.vanbaalenii_PYR-1 RVGSLVHTTFSLAGVRPARKPGKAA
TH_1589|M.thermoresistible__bu RAGALVHSTFSLAGLRPAR--GSAA
Mb1672c|M.bovis_AF2122/97 RAGALVHSTLSLAGVRPARGPSRAA
Rv1645c|M.tuberculosis_H37Rv RAGALVHSTLSLAGVRPARGPSRAA
MMAR_0288|M.marinum_M -------------------------
MUL_4835|M.ulcerans_Agy99 -------------------------
MAB_3263c|M.abscessus_ATCC_199 DAP---IEGAVAAGQ----------
MAV_2862|M.avium_104 NASADETNGVLASG-----------
MSMEG_3374|M.smegmatis_MC2_155 CSEG--KEEVPTPG-----------