For questions or suggestions e-mail us at: ioerger@cs.tamu.edu
AVRGIRALKKIMQTTFDPELVVPDEARVTEFTGDNSLSRKDLSQHPIPPGSLTWKYWGRLDVIFFGSGVV GTIAGAWPQMAKATSSSVLFTGDSSFGARSKIYKVRRQRSREYIYGTVYDAPEDAKKYGLKTRNMHKSIK GTLQDGTFHALNADTFYFGHVTFFYHLLLKVVEQLYFDGAMPRAMKEQIFEESKEWYSMWGVDDSPQPAT YDDFERYLDNIERNHLVNSQVTQVMLEQFMERRVPPRWWPPVMKKFVWPWVAGRRQVVVNSFPPHVQELF NLEWTPEDEEIARRFMRMYRRLYAILERVVPLKFLYLPIAVEGFKREGVDPRKITLESAQQALRENRARR AARENASADETNGVLASG*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. avium 104 | MAV_2862 | - | - | 100% (369) | hypothetical protein MAV_2862 |
| M. avium 104 | MAV_5226 | - | 1e-39 | 34.11% (302) | hypothetical protein MAV_5226 |
| M. avium 104 | MAV_3124 | - | 6e-34 | 31.86% (317) | hypothetical protein MAV_3124 |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb1672c | - | 2e-34 | 34.52% (281) | hypothetical protein Mb1672c |
| M. gilvum PYR-GCK | Mflv_3536 | - | 6e-35 | 33.23% (313) | hypothetical protein Mflv_3536 |
| M. tuberculosis H37Rv | Rv1645c | - | 2e-34 | 34.52% (281) | hypothetical protein Rv1645c |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | MAB_3263c | - | 1e-176 | 77.51% (369) | hypothetical protein MAB_3263c |
| M. marinum M | MMAR_0288 | - | 1e-35 | 33.45% (290) | hypothetical protein MMAR_0288 |
| M. smegmatis MC2 155 | MSMEG_3374 | - | 1e-153 | 74.25% (334) | hypothetical protein MSMEG_3374 |
| M. thermoresistible (build 8) | TH_1589 | - | 2e-32 | 32.52% (286) | CONSERVED HYPOTHETICAL PROTEIN |
| M. ulcerans Agy99 | MUL_1631 | - | 2e-33 | 32.48% (314) | hypothetical protein MUL_1631 |
| M. vanbaalenii PYR-1 | Mvan_3322 | - | 3e-34 | 33.12% (311) | hypothetical protein Mvan_3322 |
CLUSTAL 2.0.9 multiple sequence alignment
Mb1672c|M.bovis_AF2122/97 ---------------------------------------------MTVAS
Rv1645c|M.tuberculosis_H37Rv ---------------------------------------------MTVAS
MUL_1631|M.ulcerans_Agy99 ---------------------------------------------MTATS
TH_1589|M.thermoresistible__bu ----------------------------------VTEQLGLCEVPMAAKS
Mflv_3536|M.gilvum_PYR-GCK ---------------------------------------------MANDS
Mvan_3322|M.vanbaalenii_PYR-1 ---------------------------------------------MADS-
MAV_2862|M.avium_104 --------------MAVRGIRALKKIMQTTFDPELVVPDEARVTEFTGDN
MAB_3263c|M.abscessus_ATCC_199 MSKWRGIGKREEFDVVVRGIKAFKKIMQTTFDPELVIPEEVRVTEFTGDN
MSMEG_3374|M.smegmatis_MC2_155 ----------------------------------------MKVPELTGDH
MMAR_0288|M.marinum_M --------------------------MATELTAGVDFDTGVREALPMPID
Mb1672c|M.bovis_AF2122/97 RTS----------------------------------ADPLGPDSLTWKY
Rv1645c|M.tuberculosis_H37Rv RTS----------------------------------ADPLGPDSLTWKY
MUL_1631|M.ulcerans_Agy99 PPA----------------------------------ANPLGPDSLTWKY
TH_1589|M.thermoresistible__bu TTSRNRRSDAGGAGAQDFPADTPRPEPRPGPSGTTPAAQPLGPDSLTWKY
Mflv_3536|M.gilvum_PYR-GCK LSPEGSETPEGAAQPQAPG------------------AFPLGPDSLTWKY
Mvan_3322|M.vanbaalenii_PYR-1 --------------PPAAG------------------ADPLGPDSLTWKY
MAV_2862|M.avium_104 SLSRKD-----------------------------LSQHPIPPGSLTWKY
MAB_3263c|M.abscessus_ATCC_199 SLSRKD-----------------------------LCQHPIPADSLIWKY
MSMEG_3374|M.smegmatis_MC2_155 SLARNN-----------------------------LSQHPIPPGSLIWKY
MMAR_0288|M.marinum_M RPVDDE-----------------------------IVAQRLGPTSLIWKF
: . ** **:
Mb1672c|M.bovis_AF2122/97 FGDLRTGMMG-VWIGAIQNMYPELGAGVEEHSILLREPLQRVARSVYP--
Rv1645c|M.tuberculosis_H37Rv FGDLRTGMMG-VWIGAIQNMYPELGAGVEEHSILLREPLQRVARSVYP--
MUL_1631|M.ulcerans_Agy99 FGDLRIGMMG-VWIGAIQNMYPELGAGVTEHSILLREPLQRVARSVYP--
TH_1589|M.thermoresistible__bu FGDLRTGLLG-VWIGAIQNMYPELGAGVTDHSIVLQEPLQRVARSVYP--
Mflv_3536|M.gilvum_PYR-GCK FGDVRTGILG-VWIGAIQNMYPQLGAGVEDHSILMREPLQRVARSVYP--
Mvan_3322|M.vanbaalenii_PYR-1 FGDVRTGMLG-VWVGAIQNMYPQLGAGVEDHSILLREPLQRVARSVYP--
MAV_2862|M.avium_104 WGRLDVIFFGSGVVGTIAGAWPQMAKATSSSVLFTGDSSFGARSKIYKVR
MAB_3263c|M.abscessus_ATCC_199 WGRFDVMYFGSGVLGPIAGAWPQMGRGTAGSVLFNGDSSFRARAKIYKKR
MSMEG_3374|M.smegmatis_MC2_155 WGRLDVSFFGNAAMGPIAGAWPQMAQATAGSVLFTGDNSLRARAKIYKER
MMAR_0288|M.marinum_M YGDVRTQLFGFQRAAGTENCIEQLGQGVLDHSVVFSDTLGRAKRTGPP--
:* . :* . . ::. .. :. : . .
Mb1672c|M.bovis_AF2122/97 -------IMGVVYDG-DRAAQTGQQIKGYHRTIKGVDAEGRRYHALNPDT
Rv1645c|M.tuberculosis_H37Rv -------IMGVVYDG-DRAAQTGQQIKGYHRTIKGVDAEGRRYHALNPDT
MUL_1631|M.ulcerans_Agy99 -------IMGVVYDG-DRAAQTGQQIKGYHRTIKGVDADGRRYHALNPET
TH_1589|M.thermoresistible__bu -------IMGVVYDG-DRAPLTGAQIKSYHRDIKGVDAAGRRYHALNPET
Mflv_3536|M.gilvum_PYR-GCK -------IMGVVYDG-DRAAQTGAQIRGYHKTIKGVDADGRRYHALNPET
Mvan_3322|M.vanbaalenii_PYR-1 -------IMGVVYDG-DRAAQTGAQIRGFHKTIKGADSDGRRYHALNPET
MAV_2862|M.avium_104 RQRSREYIYGTVYDAPEDAKKYGLKTRNMHKSIKGTLQDG-TFHALNADT
MAB_3263c|M.abscessus_ATCC_199 RQRSREYIYGSVYDPPEDAKKYGLKTRNMHKSVKGTLQDG-TFHALNAET
MSMEG_3374|M.smegmatis_MC2_155 TRRSHEYIYSTVYDAPEDAKKYGLKIRNMHKPVKGKLKDG-TFNALNAET
MMAR_0288|M.marinum_M -------LMRTVYSE--DPHGWGRTVRDFHKPIKGTIGDGSRYHALNPEL
: **. . * :. *: :** * ::***.:
Mb1672c|M.bovis_AF2122/97 FYWAHATFF---MLVIKVAEYFCGGLTEAEKHQLFEEHVRWYRMYGMSMR
Rv1645c|M.tuberculosis_H37Rv FYWAHATFF---MLVIKVAEYFCGGLTEAEKHQLFEEHVRWYRMYGMSMR
MUL_1631|M.ulcerans_Agy99 FYWAHATFF---MLVVKVAEYFCGGLTEAEKRQLFDEYVQWYRMYGMSMR
TH_1589|M.thermoresistible__bu FYWAHATFF---MLILKTAEYFCGGLTEAEKHQLFDEHVRWYRMYGMSMR
Mflv_3536|M.gilvum_PYR-GCK FYWAHATFF---MLIIKTAEYFCGGLTEAEKEQLFDEHVQWYRMYGMSMA
Mvan_3322|M.vanbaalenii_PYR-1 FYWAHATFF---MLIIKTAEYFCGGLTEAEKRQLFDEHVQWYRMYGMSMQ
MAV_2862|M.avium_104 FYFGHVTFFYHLLLKVVEQLYFDGAMPRAMKEQIFEESKEWYSMWGVDDS
MAB_3263c|M.abscessus_ATCC_199 FYFAHVTFFYHHLMVVTERLHFDGDMPRAVKEQIFEESKEWYSMWGVDDG
MSMEG_3374|M.smegmatis_MC2_155 FYFAHVTFFYYLLIRVVEQLHFDGSMPRAMKEQIFEESKEWYSLLGVDDS
MMAR_0288|M.marinum_M FYWAHATFVD---QILYNTDTFIRRLSRAEKEQIFEESKIWYGLYGVSDR
**:.*.**. : * :..* *.*:*:* ** : *:.
Mb1672c|M.bovis_AF2122/97 PVPKSWEDFQDYWDRVCRDKLEINQATVDILQMRIPKPRFVLMPTPIWDQ
Rv1645c|M.tuberculosis_H37Rv PVPKSWEDFQDYWDRVCRDKLEINQATVDILQMRIPKPRFVLMPTPIWDQ
MUL_1631|M.ulcerans_Agy99 PVPETWEDFQDFWERVGRDELEINQATLDIFNMRIPKPKFVLMPIGIWDQ
TH_1589|M.thermoresistible__bu PVPRTWEEFCEYWDRTCREQLEINQAALDILHIRIPKPWFVLMPTPVWDQ
Mflv_3536|M.gilvum_PYR-GCK PVPESWQAFCEYWDRKCREELEINSATLDILSMRIPKPWFVLMPTPVWDQ
Mvan_3322|M.vanbaalenii_PYR-1 PVPESWEAFCEYWDRKCREELEINKATLDIFSMRIPKPWFVMMPTPLWDQ
MAV_2862|M.avium_104 PQPATYDDFERYLDNIERNHLVNSQVTQVMLEQFMERRVPPRWWPPVMKK
MAB_3263c|M.abscessus_ATCC_199 PQPDTYDDFERYLENVERNHLVRSQVTQLMLEQFMERRLAPRWWPTAMKK
MSMEG_3374|M.smegmatis_MC2_155 AQPGTYDDFERYLENIERNKLVRSQVTELMLEQFMERRVAPRWWPPVMKK
MMAR_0288|M.marinum_M SQPQTYDEFVAYWDGMLDRFVPHKTVLYGTGYLRKGIPGPRKLPALIWRI
. * ::: * : : : . .
Mb1672c|M.bovis_AF2122/97 LFKPLIAGQRWIAAGLFDPAVREKAGMHWTPGDEVLLRVFGKVVELAFLA
Rv1645c|M.tuberculosis_H37Rv LFKPLIAGQRWIAAGLFDPAVREKAGMHWTPGDEVLLRVFGKVVELAFLA
MUL_1631|M.ulcerans_Agy99 LFRPLVAGQRWIAAGLFEPAVREKAGMHWTQGDEVLLRLFGKAVELAFLA
TH_1589|M.thermoresistible__bu LFRPLLAGQRWVAAGVFEPVLREKAGMRWTPGDEVLLRLFGKLVELAFVA
Mflv_3536|M.gilvum_PYR-GCK MFKPMIGAQRWIAAGVFDPVVRERAGMRWTPGDEIVLRLFGKMVELAFVA
Mvan_3322|M.vanbaalenii_PYR-1 IFKPMVGAQRWIAAGVFDPVVRERAGMRWTPGDEIVLRLFGKLVELAFLA
MAV_2862|M.avium_104 FVWPWVAGRRQVVVNSFPPHVQELFNLEWTPEDEEIARRFMRMYRRLYAI
MAB_3263c|M.abscessus_ATCC_199 FVWPWLVGRRQVVVSSYPPHVRELFALEWTPEDEEMLRRFMDMYRRCYAV
MSMEG_3374|M.smegmatis_MC2_155 YVWPWLAARRQIVVNCYPAHVKDLFGLEWTPEDEDMSRRFMHMYRRLSAV
MMAR_0288|M.marinum_M LSAPLNAYARLVIVGTLPPQMREVCDLDWNAKKERRFQRFAALIRGLNPV
* * : .. . ::: : *. .* : * .
Mb1672c|M.bovis_AF2122/97 VPDEIRLHPRALAAYRRAAGRTRHDAPLVQAPGFMAPPRDRQGLPMHYFP
Rv1645c|M.tuberculosis_H37Rv VPDEIRLHPRALAAYRRAAGRTRHDAPLVQAPGFMAPPRDRQGLPMHYFP
MUL_1631|M.ulcerans_Agy99 VPDEIRLHPRALAAYRRAEGRVKRDAPLVEAPSFMAPPSDRRGLPMHYFP
TH_1589|M.thermoresistible__bu VPDEIRLHPRALSAYRRASGRIPADAPLVEAPAFTGPPGDRRGLPMHYVP
Mflv_3536|M.gilvum_PYR-GCK VPDEIRLHPRAVAAYRRAEGKVPADAPLVEAPAFMAPPRDRRSMPMHYLP
Mvan_3322|M.vanbaalenii_PYR-1 VPDEIRLHPRAVAAYRRAEGKIPADAPLVEAPAFMAPPRDRRHMPMHYLP
MAV_2862|M.avium_104 LERVVPLKFLYLPIAVEGFKREGVDPRKITLESAQQALRENR--------
MAB_3263c|M.abscessus_ATCC_199 LERLLPVKCFYLPTAVRGFEREGIDPRNITLESARQALRDNR--------
MSMEG_3374|M.smegmatis_MC2_155 VERFVPLRLLYLPIAARGFEREGIDPRDVTLESAQRTLRESR--------
MMAR_0288|M.marinum_M LG-RLPVRLIYLPWAAQAWTRSGVDPRRLHRRAVST--------------
: : :: :. .. : *. : .
Mb1672c|M.bovis_AF2122/97 PRSHRFTRSALDPAKALMERAGALVHSTLSLAGVRPARGPSRAA---
Rv1645c|M.tuberculosis_H37Rv PRSHRFTRSALDPAKALMERAGALVHSTLSLAGVRPARGPSRAA---
MUL_1631|M.ulcerans_Agy99 PRAH--------PAKVLLERAGSLVHSTLSIAGLQPARGRSRTTTAA
TH_1589|M.thermoresistible__bu RRRS------------LIERAGALVHSTFSLAGLRPARGSAA-----
Mflv_3536|M.gilvum_PYR-GCK PRKT------------LLDRVGSLVHSTFSLAGRRPARGTGKAA---
Mvan_3322|M.vanbaalenii_PYR-1 PQKS------------LLDRVGSLVHTTFSLAGVRPARKPGKAA---
MAV_2862|M.avium_104 ------------------ARRAARENASADETNGVLASG--------
MAB_3263c|M.abscessus_ATCC_199 ------------------ARRAPRKDAP---IEGAVAAGQ-------
MSMEG_3374|M.smegmatis_MC2_155 ------------------ARWAAQKCSEG--KEEVPTPG--------
MMAR_0288|M.marinum_M -----------------------------------------------