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MTPIGVGVIGASPNGGWAALAHVPALRALPEYDLRAVATSRPESAERAKVAWGVDAYHDPRRLVERRDID LVVVAVKVPDHYGLITDALTAGKAVFSEWPLGVALEQAQILHAEAVVAGVPTVVGLQARFAPAIRRMREL VDAGYVGKVLSTNIVGSGMAWAPGAPAAQAYAFDARNGVTTLTVSTAHALDALSYVLGDISSVTSTLGVG NDTITLDDGSTTTVTSPDQVAVTAQLESGAVASVFYRGGLSRAGNLRWEINGTHGDLLLTSPAPNGNIQA TELVLAGANGSATHLEPIHTHDAHPETGLSGPANTVANLYRAFAHDQLLGTAAAPTFGDAVALHRLIAGI EHVNTESHRKY
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. smegmatis MC2 155 | MSMEG_3300 | - | - | 100% (361) | oxidoreductase, Gfo/Idh/MocA family protein |
| M. smegmatis MC2 155 | MSMEG_4650 | - | 2e-10 | 27.03% (259) | oxidoreductase YisS |
| M. smegmatis MC2 155 | MSMEG_2637 | - | 3e-08 | 25.95% (185) | oxidoreductase, Gfo/Idh/MocA family protein |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | - | - | - | - | - |
| M. gilvum PYR-GCK | Mflv_2613 | - | 4e-10 | 25.95% (262) | inositol 2-dehydrogenase |
| M. tuberculosis H37Rv | - | - | - | - | - |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | MAB_2306c | - | 2e-09 | 35.54% (121) | putative oxidoreductase |
| M. marinum M | - | - | - | - | - |
| M. avium 104 | MAV_2643 | - | 6e-26 | 27.33% (344) | oxidoreductase family protein, NAD-binding Rossmann fold |
| M. thermoresistible (build 8) | TH_3104 | - | 1e-07 | 24.70% (336) | PUTATIVE oxidoreductase domain protein |
| M. ulcerans Agy99 | - | - | - | - | - |
| M. vanbaalenii PYR-1 | Mvan_3968 | - | 7e-10 | 25.00% (260) | inositol 2-dehydrogenase |
CLUSTAL 2.0.9 multiple sequence alignment
Mflv_2613|M.gilvum_PYR-GCK ---MTSLGLIGLG----RIGAFHTETLINLPEVSRLVITDERPGVVGEVA
Mvan_3968|M.vanbaalenii_PYR-1 ---MTTLGLIGLG----RIGAFHAETLTNLPEVSGLVVTDERPEVVSQLA
MAV_2643|M.avium_104 --MTLRVGIIGVG----WGARVQVPGFRAAKGFEPVALCARTPDRLERAA
TH_3104|M.thermoresistible__bu ----MRVLVIGTG----FGRQAMAPVYRGL-GFDVEVVSPRDESALHRAL
MSMEG_3300|M.smegmatis_MC2_155 -MTPIGVGVIGASPNGGWAALAHVPALRALPEYDLRAVATSRPESAERAK
MAB_2306c|M.abscessus_ATCC_199 MPESIRWGIVGPG----RIAGNVARDFPLTPRAELAAVASRSLPRAQDFA
::* . . . .:
Mflv_2613|M.gilvum_PYR-GCK AKYGATPVESVEKLLSS--GIDGVVVAAATPAHAELTLAAVERGLPTFCE
Mvan_3968|M.vanbaalenii_PYR-1 TKYGATPANSVQELLAS--GVDGVIVAAATPAHAELTLAAVERGLPTFCE
MAV_2643|M.avium_104 AKLGIEQTSTDWQSFVTRDDLDVISVATPTVLHHEMTIAALAAGKPVLCE
TH_3104|M.thermoresistible__bu NAG-----------------VDLVSVHSPPFLHRQHVTAAVDRGYPVLCD
MSMEG_3300|M.smegmatis_MC2_155 VAWGVDAYHDPRRLVERR-DIDLVVVAVKVPDHYGLITDALTAGKAVFSE
MAB_2306c|M.abscessus_ATCC_199 GAHQIPRAYGSYRELLADPDIDAVYIATPHPQHRQTAIAALTAGKAILVE
:* : : * *: * . : :
Mflv_2613|M.gilvum_PYR-GCK KPIASTAAESARVAEIIARSGVPVQVGYQRRFDTAFAAVKQAADSGSLGA
Mvan_3968|M.vanbaalenii_PYR-1 KPIAATAAESARVGEVITRSGVPVQVGYQRRFDAAFAAVKHAVDDGSLGA
MAV_2643|M.avium_104 KPLAGDLEAARHMVRAATDSKLPTACCFENRWNPDWLAVADKVRSGFLGS
TH_3104|M.thermoresistible__bu KPFGRNADEARAMRDHAARRAVPTFLNFELRHQPARAEFKKLADSGVIGT
MSMEG_3300|M.smegmatis_MC2_155 WPLGVALEQAQILHAEAVVAGVPTVVGLQARFAPAIRRMRELVDAGYVG-
MAB_2306c|M.abscessus_ATCC_199 KTFTATVSGAQEVIDIARARGVFAMEAMWTRFQPAIVAAKDLVDDGAIGE
.: : : : . * . . . * :*
Mflv_2613|M.gilvum_PYR-GCK LHTVRSTTMDP--APPPMDYIRG--------SGGIFRDCAVHDFDVIRWV
Mvan_3968|M.vanbaalenii_PYR-1 LHTVRSTTMDP--APPPMDYIKG--------SGGIFRDCAVHDFDVIRWV
MAV_2643|M.avium_104 QYLARVSRSAS--YWHPSHPLQAHWMYDREQGGGYLAGMLVHDLDFLTSL
TH_3104|M.thermoresistible__bu PRHLSWTFFGAGLRGRPHGWINE-----RDTGGGWIGANGAHLIDYTRYL
MSMEG_3300|M.smegmatis_MC2_155 -KVLSTNIVGSGMAWAPGAPAAQAYAFDARNGVTTLTVSTAHALDALSYV
MAB_2306c|M.abscessus_ATCC_199 VRQVQADLGVDRPFDREDRLFNP------ALGGGALLDLGVYVVSLAQYF
. : .: .. .
Mflv_2613|M.gilvum_PYR-GCK TGQNVVEVYATG-SVQGDPLFTEYG-----DVDTAAIVVRFDGGALGVVS
Mvan_3968|M.vanbaalenii_PYR-1 TGQNVVDVYATG-SVQGDPRFAEYG-----DVDTAAVVVRFDGGALGVVS
MAV_2643|M.avium_104 LGRPVSVCAEVR-TSDPVRELPDGGTLPVTADDTAALLMRMESGVTVILS
TH_3104|M.thermoresistible__bu FGSEITGCGGVARIEDPHRPDPQGRPRRATAEDAYSAWFVTENGCTATHD
MSMEG_3300|M.smegmatis_MC2_155 LGDISSVTSTLG-VGNDTITLDDGSTTTVTSPDQVAVTAQLESGAVASVF
MAB_2306c|M.abscessus_ATCC_199 LGDPAAVVAHGSLFPTG-------------VDAEAGLLLRYDDGRTATLL
* . :.*
Mflv_2613|M.gilvum_PYR-GCK AARYNGRGYDCRLEVHGFDDTVVAG-------WDQGAPVRNADP----AN
Mvan_3968|M.vanbaalenii_PYR-1 AARYNGRGYDCRLEVHGFDDTVVAG-------WDQGAPVRNADPDFSSPG
MAV_2643|M.avium_104 LSVMGAHADHYRLELFGSDGTIIGDGDLRSAAYSLGAATDAGLSPLTVDE
TH_3104|M.thermoresistible__bu TAFAAAVALPPRMVLTGSAGALELIG-------DSRLIVHRADADPMTHE
MSMEG_3300|M.smegmatis_MC2_155 YRGGLSRAGNLRWEINGTHGDLLLTSPAPNGNIQATELVLAGANGSATHL
MAB_2306c|M.abscessus_ATCC_199 CSLLHHTPGQAR--IFGTEGWIDILP-------RFHHPREIVLHRKGAAP
* : * . :
Mflv_2613|M.gilvum_PYR-GCK DFPTGQP--HHFFMDRFTEAFRTELSSFVDVVEGGPNLGATVADAVEVAW
Mvan_3968|M.vanbaalenii_PYR-1 AFPAGPP--HHFFMDRFTEAFRAELRAFVDVVEGGPIRGATVADAVEVAW
MAV_2643|M.avium_104 REPAHPERLPGGLAGHASRAMALMLQDWLPAFDGGPSGAATFEDGLLSLA
TH_3104|M.thermoresistible__bu FPPAPPR-------SFYEPALTPWLEQVADALRTGRPATPSFDDGVAVAE
MSMEG_3300|M.smegmatis_MC2_155 EPIHTHDAHPETGLSGPANTVANLYRAFAHDQLLGTAAAPTFGDAVALHR
MAB_2306c|M.abscessus_ATCC_199 EPMVRPP-----VGGGYSHELAEVTECLLNGR--AQSSVMPLADTLAVQR
. . . .. * :
Mflv_2613|M.gilvum_PYR-GCK IAEAATESLRRGVPVTIDSVRKEAQQ
Mvan_3968|M.vanbaalenii_PYR-1 IAEAATESLRRGVPVTIESVRKETQQ
MAV_2643|M.avium_104 VIDAAHRSAEGGGWEQVQV-------
TH_3104|M.thermoresistible__bu VMDRLRANVIEQVMQ-----------
MSMEG_3300|M.smegmatis_MC2_155 LIAGIEHVNTESHRKY----------
MAB_2306c|M.abscessus_ATCC_199 VLNTACEQLGVDHTEDPADLD-----
: