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MAGRVSIGDFAVMTHLSRKALRHYHEMGVLVPAHIDAHTGYRFYDTCQVDHARIIRRFRELDMPIPDIKA LLAAGDGATRNEIIAAHLRRMEEQLAQTRDAVTELRELLDPVRVPAHIEVRHQPATEVWAVSAEVHSSQI GAWFAASVDTLQRALSDSGVRIDGAMGGVYDRELFAGESGVATLYVPVPHTVPVPPTVQAQTVPAQELAV LVHPGSQAGIDRSYGELGAYVYDHLISHQGPIRERYVGAPASNIVAFTATEIGWPILATSPSQPPVP
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. smegmatis MC2 155 | MSMEG_3274 | - | - | 100% (277) | MerR-family protein transcriptional regulator |
| M. smegmatis MC2 155 | MSMEG_1447 | - | 1e-07 | 32.52% (123) | transcriptional regulator, MerR family protein |
| M. smegmatis MC2 155 | MSMEG_2194 | - | 2e-05 | 24.53% (106) | MerR-family protein transcriptional regulator |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb3367 | - | 2e-07 | 29.50% (139) | MerR family transcriptional regulator |
| M. gilvum PYR-GCK | Mflv_0932 | - | 7e-88 | 59.42% (276) | MerR family transcriptional regulator |
| M. tuberculosis H37Rv | Rv3334 | - | 2e-07 | 29.50% (139) | MerR family transcriptional regulator |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | - | - | - | - | - |
| M. marinum M | MMAR_0009 | - | 2e-07 | 27.36% (106) | transcriptional regulator |
| M. avium 104 | MAV_1646 | - | 2e-06 | 31.82% (110) | transcriptional regulator, MerR family protein |
| M. thermoresistible (build 8) | - | - | - | - | - |
| M. ulcerans Agy99 | MUL_0011 | - | 1e-07 | 27.36% (106) | transcriptional regulator |
| M. vanbaalenii PYR-1 | Mvan_3507 | - | 4e-48 | 37.50% (272) | MerR family transcriptional regulator |
CLUSTAL 2.0.9 multiple sequence alignment
MSMEG_3274|M.smegmatis_MC2_155 ---------------MAG-RVSIGDFAVMTHLSRKALRHYHEMGVLVPAH
Mflv_0932|M.gilvum_PYR-GCK MTAPPHRRRNAEEDVVGA-RVSIGDFAVMTSLSRKALRHYHDIGILEPAH
Mvan_3507|M.vanbaalenii_PYR-1 MAAICDSAGVKREAVQASPKLTIGEFATVTHLSVRTLRRYHEGGLLEPAW
Mb3367|M.bovis_AF2122/97 --------------------MKISEVAALTNTSTKTLRFYENSGLLPPP-
Rv3334|M.tuberculosis_H37Rv --------------------MKISEVAALTNTSTKTLRFYENSGLLPPP-
MMAR_0009|M.marinum_M -----------------MDGLTVGQVAERFGITVRTLHHYDEIGLLIPS-
MUL_0011|M.ulcerans_Agy99 -----------------MDGLTVGQVAERFGITVRTLHHYDEIGLLIPS-
MAV_1646|M.avium_104 ----------------MAEQLLIGDVTALTGIASGRIRHYEKIGLLHAD-
: :.:.: : :: *.. *:* .
MSMEG_3274|M.smegmatis_MC2_155 IDAHTGYRFYDTCQVDHARIIRRFRELDMPIPDIKALLAAGDGATRNEII
Mflv_0932|M.gilvum_PYR-GCK IDSHTGYRFYDTGQVDHAHIIRRFRSLGMSIPDIKALLSADGAAARTEII
Mvan_3507|M.vanbaalenii_PYR-1 VDGYTGYRYYTPEQIPTAQVIHRLRQLDVPLADIESILTADDPQHRAQVI
Mb3367|M.bovis_AF2122/97 ARTASGYRNYGPEIVDRLRFIHRGQAAGLALQEVRQILAIHD---RGEAP
Rv3334|M.tuberculosis_H37Rv ARTASGYRNYGPEIVDRLRFIHRGQAAGLALQEVRQILAIHD---RGEAP
MMAR_0009|M.marinum_M RRAASGYRVYTSADLTRLSQVIVYRRLELPLDEIARLLDEGN----AVSH
MUL_0011|M.ulcerans_Agy99 RRAASGYRVYTSADLTRLSQVIVYRRLELPLDEIARLLDEGN----AVSH
MAV_1646|M.avium_104 -HLSNGYRVFDVEQVLDLLRIDLMRSLGVGINDIQRLLHGGHS--TLADL
.*** : : : : : : :: :*
MSMEG_3274|M.smegmatis_MC2_155 AAHLRR-MEEQLAQTRDAVTELRELLDPVRVPAHIEVRHQPATEVWAVSA
Mflv_0932|M.gilvum_PYR-GCK TTHLTQ-MEVQLQHTRDTVSALRELLSPVSVPSHVEVHAKPALAVWSVGA
Mvan_3507|M.vanbaalenii_PYR-1 SDHLRR-LEAELDRTRAAVVSLHRLLNPEPADLEVQLLSVPARTVAGISG
Mb3367|M.bovis_AF2122/97 CAHVRQLLSTRIDEVRAQIAELIALEGHLQTLLDHASYGPPTEHDHSTVC
Rv3334|M.tuberculosis_H37Rv CAHVRQLLSTRIDEVRAQIAELIALEGHLQTLLDHASYGPPTEHDHSTVC
MMAR_0009|M.marinum_M LVRQRERVMARLDEMKDLVEAIDQALEKAMTNTPMTDDDMRELFGDGFDD
MUL_0011|M.ulcerans_Agy99 LVRQRERVMARLDEMKDLVEAIDLALEKAMTNTPMTDDDMRELFGDGFDD
MAV_1646|M.avium_104 LDEHRALLIQQRDRLDQLIRALDESCAQSRAAADGTDVSEHLLRQLATTH
. : . . : : . .
MSMEG_3274|M.smegmatis_MC2_155 EVHSSQIGAWFAASVDTLQRALSDSG-VRIDGAMGGVYDRELFAGESGVA
Mflv_0932|M.gilvum_PYR-GCK TIEVSEIDDWFGRSLKTLRDAVTAAGSAALGHQPGGLYDRALFLESRGAA
Mvan_3507|M.vanbaalenii_PYR-1 HVRQEDSLTWYDSAMAELDAAFPPAE---HTGPPGGRYDNELFTHGAGAF
Mb3367|M.bovis_AF2122/97 WILESDLDEPTAIEVSDIHA------------------------------
Rv3334|M.tuberculosis_H37Rv WILESDLDEPTAIEVSDIHA------------------------------
MMAR_0009|M.marinum_M YRAETEQKWGETTEWKESQRRTRSYGKDEWVRIKAEGQAVEKTLSDAFRA
MUL_0011|M.ulcerans_Agy99 YRVETEQKWGETAEWKESQRRTKSYGKDEWVRIKAEGQAIEKALSDAFRA
MAV_1646|M.avium_104 RDSIGVIGRLSAPLPAPVAAMYADLFDEWDLPVPALFGQMRLPSAASTLL
MSMEG_3274|M.smegmatis_MC2_155 TLYVPVPHTVPVPPTVQAQTVPAQELAVLVHPGSQAGIDRSYGELGAYVY
Mflv_0932|M.gilvum_PYR-GCK TLFVPALHSADPPEGVRAEVLPPAEFAVLRHCGGHDGIDRSYGALGRYVN
Mvan_3507|M.vanbaalenii_PYR-1 AVFRPVRNPKPAG-RIRVLELPQADLAVTVHTGRHDDIDVTYGRLGSWVV
Mb3367|M.bovis_AF2122/97 --------------------------------------------------
Rv3334|M.tuberculosis_H37Rv --------------------------------------------------
MMAR_0009|M.marinum_M GLPADSEEAMNAAEQHRRHVN---RWFYDCPPAFHRSLGDMYVSDPRYIA
MUL_0011|M.ulcerans_Agy99 GLPADSEEAMNAAEQHRRHVN---RWFYDCPPAFHRNLGDMYVSDPRYIA
MAV_1646|M.avium_104 AQLAETPGRQVLFDRLRRLAADVIALGESVSAATELAHNWIEQQLADPLP
MSMEG_3274|M.smegmatis_MC2_155 DHLISHQGPIRERY-VGAPASNIVAFTATEIGWPILATSPSQPPVP----
Mflv_0932|M.gilvum_PYR-GCK EHLISHQGPIREHY-IGATPSTPTTFTATEICWPIFGATP--PPQ-----
Mvan_3507|M.vanbaalenii_PYR-1 THALAVDGPIHETYSVGPRDTTDPAEWRTEIGWPVFRLAAGEPSAQK---
Mb3367|M.bovis_AF2122/97 --------------------------------------------------
Rv3334|M.tuberculosis_H37Rv --------------------------------------------------
MMAR_0009|M.marinum_M TYDESFGLPGLAAYCREAIHANANRTGG----------------------
MUL_0011|M.ulcerans_Agy99 TYDESFGLPGLAAYCREAIHANANRAGG----------------------
MAV_1646|M.avium_104 DDVVTVLRGVQPLLGQDPVIVQGFRAWAGSISPAAARFIEEIARQTARRG
MSMEG_3274|M.smegmatis_MC2_155 ----------------------
Mflv_0932|M.gilvum_PYR-GCK ----------------------
Mvan_3507|M.vanbaalenii_PYR-1 ----------------------
Mb3367|M.bovis_AF2122/97 ----------------------
Rv3334|M.tuberculosis_H37Rv ----------------------
MMAR_0009|M.marinum_M ----------------------
MUL_0011|M.ulcerans_Agy99 ----------------------
MAV_1646|M.avium_104 LAAVSVIVLPAADRAQTADATP