For questions or suggestions e-mail us at: ioerger@cs.tamu.edu
VNAFTEWLDDSILFTTDAVPVAVGQTLQLVFVPFFFVVLLGIPLGVLLYVTAPGGLAPIRWLNSSLGVVV NVTRSLPFLVLVIALWPLGRLLVGSSLGTVAAMVPLTIGTIPFLARLVESSLREVDSGKIDAARVVGATR WQIITKTLLPEAISGIIAGLTITIIALLGFSALAGVIGGGGLGDLAIRYGARSYDGPVLWSTVLLLIVFA QIFQVVGDYFARKTDHRARRSAGGAGDAGEAQRLSA
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. smegmatis MC2 155 | MSMEG_3057 | - | - | 100% (246) | ABC-type metal ion transport system, permease component |
| M. smegmatis MC2 155 | MSMEG_5808 | - | 1e-40 | 43.15% (197) | binding-protein-dependent transport systems inner membrane |
| M. smegmatis MC2 155 | MSMEG_0646 | - | 3e-14 | 27.04% (196) | putative transporter |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb3782c | proZ | 2e-09 | 29.53% (149) | osmoprotectant (glycine betaine/carnitine/choline/L-proline) |
| M. gilvum PYR-GCK | Mflv_1210 | - | 2e-11 | 31.21% (157) | binding-protein-dependent transport systems inner membrane |
| M. tuberculosis H37Rv | Rv3756c | proZ | 2e-09 | 29.53% (149) | osmoprotectant (glycine betaine/carnitine/choline/L-proline) |
| M. leprae Br4923 | MLBr_02093 | pstA1 | 2e-07 | 24.48% (143) | membrane-bound component of phosphate transport |
| M. abscessus ATCC 19977 | MAB_2802c | - | 4e-39 | 41.26% (206) | ABC transporter permease |
| M. marinum M | MMAR_0033 | - | 3e-10 | 35.58% (104) | hypothetical protein MMAR_0033 |
| M. avium 104 | MAV_0766 | pstA | 9e-11 | 22.73% (198) | phosphate ABC transporter, permease protein PstA |
| M. thermoresistible (build 8) | TH_2403 | - | 1e-41 | 39.81% (211) | binding-protein-dependent transport systems inner membrane |
| M. ulcerans Agy99 | MUL_4374 | proZ | 1e-08 | 30.34% (145) | osmoprotectant (glycine betaine/carnitine/choline/L-proline) |
| M. vanbaalenii PYR-1 | Mvan_3885 | - | 1e-41 | 42.20% (218) | binding-protein-dependent transport systems inner membrane |
CLUSTAL 2.0.9 multiple sequence alignment
Mb3782c|M.bovis_AF2122/97 ------------------------------------------------MN
Rv3756c|M.tuberculosis_H37Rv ------------------------------------------------MN
MUL_4374|M.ulcerans_Agy99 ------------------------------------------------MN
Mflv_1210|M.gilvum_PYR-GCK ------------------------------------------------MN
TH_2403|M.thermoresistible__bu --------------------------------------------------
Mvan_3885|M.vanbaalenii_PYR-1 --------------------------------------------------
MAB_2802c|M.abscessus_ATCC_199 --------------------------------------------------
MSMEG_3057|M.smegmatis_MC2_155 --------------------------------------------------
MLBr_02093|M.leprae_Br4923 MNLDTLDRPVKAVVLRPISVRRRIKNNVATMFFFTSFLIALVPLVWLLSV
MAV_0766|M.avium_104 -MTSMLDRPLKSRTFSPLSRRRRAANSVATVLVSVSLLVAVTPLVMVLCS
MMAR_0033|M.marinum_M -MSVAGNDINVEGAVKGGAEGPPTAPTTPGRPSVGRWALQPLTCAFAVAG
Mb3782c|M.bovis_AF2122/97 FLQQALSYLLTASNWTGPVG--LAVRTCEHLEYTAVAVAASALIAVPVGL
Rv3756c|M.tuberculosis_H37Rv FLQQALSYLLTASNWTGPVG--LAVRTCEHLEYTAVAVAASALIAVPVGL
MUL_4374|M.ulcerans_Agy99 FLQQALSYLSTAANWTGSAG--LAHRTAEHLEYTALAATASALVAIPIGL
Mflv_1210|M.gilvum_PYR-GCK FLQEALSFIFTAANWAGPAG--LTARILEHLQYTVIAVFFSALIAVPLGM
TH_2403|M.thermoresistible__bu VTSVLAAG--TVPLDEMAGL--LFPALLDTLTMVGIVMTIVTLVGVPLGA
Mvan_3885|M.vanbaalenii_PYR-1 -MNYLALDDFSTPWLKVPDL--LLPAYGETWVMVGVTMVLVVLIGTPAGI
MAB_2802c|M.abscessus_ATCC_199 ---------MTTNWERLRPQ--LFEAFGDTLYMVSITLVVGGLVGLALGV
MSMEG_3057|M.smegmatis_MC2_155 --MNAFTEWLDDSILFTTDA--VPVAVGQTLQLVFVPFFFVVLLGIPLGV
MLBr_02093|M.leprae_Br4923 VVARGFYAVTRFDWWTHSLRGVMPEEFAGGVYHALYGSLVQAVVAAIMAV
MAV_0766|M.avium_104 VVVKGFRAITSTVWWSHSQAGMTAFVTGGGAYHALVGTVLQGLVCAAISI
MMAR_0033|M.marinum_M ALAYVTVADVSESERRSLSVSHLLQLLREHLVISLSATVLTCVVAIPVGI
:: .
Mb3782c|M.bovis_AF2122/97 LIGHTGRGTLLVVG-----------AVNGLRALP----TLGVLLLGVLLF
Rv3756c|M.tuberculosis_H37Rv LIGHTGRGTLLVVG-----------AVNGLRALP----TLGVLLLGVLLF
MUL_4374|M.ulcerans_Agy99 IIGHTGRGQLLVVS-----------AVNGLRALP----TLGVLLLGVLLF
Mflv_1210|M.gilvum_PYR-GCK LIGHTGRGTFVVVT-----------GVNALRALP----TLGVLLLGVLLW
TH_2403|M.thermoresistible__bu LVHNLAPGGLFENPTL---HTVLSWTINIGRSLPFLILMAAIMPFTRFVT
Mvan_3885|M.vanbaalenii_PYR-1 ILHNTSTLGLFPNPRV---FTVLNTVVNVGRSLPFLILMAAIIPVTRFLV
MAB_2802c|M.abscessus_ATCC_199 LLYTTRSGGLLQNRLL---HTLLNVVVNIVRPIPFVVLIAALGPITLGVV
MSMEG_3057|M.smegmatis_MC2_155 LLYVTAPGGLAPIRWL---NSSLGVVVNVTRSLPFLVLVIALWPLGRLLV
MLBr_02093|M.leprae_Br4923 PLGSMTAVYLVEYGSG-PFVRVTTFMVDVLAGVPSIVAALFIFCLWIATL
MAV_0766|M.avium_104 PIGLMVAIYLVEYGGGTPLGRLASFMVDILSGVPSIVAALFVYALCVATL
MMAR_0033|M.marinum_M ALTRGSMRRYSKPIIT---------VAGFGQAAP----AIGLIALGAVVF
: . * : .
Mb3782c|M.bovis_AF2122/97 G--LGLGPPLVALMLLGIPSLLASTYAGIASVDPLVVDAARAMGMTESQV
Rv3756c|M.tuberculosis_H37Rv G--LGLGPPLVALMLLGIPSLLASTYAGIASVDPLVVDAARAMGMTESQV
MUL_4374|M.ulcerans_Agy99 G--LGLGPPIVALMLLGMPPLLAGTYAGIASVDPLVVDAARAMGMTEAQV
Mflv_1210|M.gilvum_PYR-GCK G--LGLIPPTVALMLLGIPPLLAGTYSGIANVDRSVVDAARSMGMTESRI
TH_2403|M.thermoresistible__bu GTNIGIAAAVVPMSLAGIAFFTRIVENSLRSVPPSVVQVARASGGSPLQI
Mvan_3885|M.vanbaalenii_PYR-1 GTTIGIAAAIVPMTVAGIPFFARLVQNALREVRSDVTDMGLVSGGSHVQV
MAB_2802c|M.abscessus_ATCC_199 GTTIGTTAVVFVMIVAASFAIARIVEQNLVTIDPGVIEAARAVGAGPLRI
MSMEG_3057|M.smegmatis_MC2_155 GSSLGTVAAMVPLTIGTIPFLARLVESSLREVDSGKIDAARVVGATRWQI
MLBr_02093|M.leprae_Br4923 GFQQSAFAVSLALVLLMLPVVVRSTEEILRLVPDELREACYALGIPKWKT
MAV_0766|M.avium_104 GLPRSEFAVSLALVLLMLPVIVRATEEMLRIVPVDLREASYALGITKWKT
MMAR_0033|M.marinum_M G--IGQLGAIVALTVYGAMPIIANTVTGLDGVDRRIVEAARGMGLSAFST
* . . : : . . : : : *
Mb3782c|M.bovis_AF2122/97 LLRVEVPNALPLMLGGLRSATLQVVATATVAAYAS--------------L
Rv3756c|M.tuberculosis_H37Rv LLRVEVPNALPLMLGGLRSATLQVVATATVAAYAS--------------L
MUL_4374|M.ulcerans_Agy99 VLRVEMPNALPLILGGLRSATLQVVATVTVAAYAS--------------L
Mflv_1210|M.gilvum_PYR-GCK LLRVETPNALPLILGGLRTATLQIVATATVAAYAS--------------L
TH_2403|M.thermoresistible__bu IRTAQLHEAVPSILGGLTINVIAMIEYSAIAGTIG--------------A
Mvan_3885|M.vanbaalenii_PYR-1 IRSVQLSEALPALAGALTVNTIAMIEYSAIAGSIG--------------A
MAB_2802c|M.abscessus_ATCC_199 IVTLLVPEALGPLILGYTFVLIGIVDMSAMAGLVG--------------G
MSMEG_3057|M.smegmatis_MC2_155 ITKTLLPEAISGIIAGLTITIIALLGFSALAGVIG--------------G
MLBr_02093|M.leprae_Br4923 IVRIVFPIATPGIISGVLLSIARVIGETAPVLVLVGYSRSINFDIFDGNM
MAV_0766|M.avium_104 IARVVLPTGLSGIVTGILLAMARVMGETAPLLILVGYAQSMNFDIFSGFM
MMAR_0033|M.marinum_M LRRVELPLSLPVIVAGVRTALVLIVGTAALASFTG--------------G
: . : . :: :
Mb3782c|M.bovis_AF2122/97 GGLGGYLIDGIKERRFHIALVGAMMVAALALTLDGLLALAGWVSVPGTGR
Rv3756c|M.tuberculosis_H37Rv GGLGGYLIDGIKERRFHIALVGAMMVAALALTLDGLLALAGWVSVPGTGR
MUL_4374|M.ulcerans_Agy99 GGLGRYLIDGIKERQSHIALVGALMVAALALSLDGLLALAGWASVPGTGR
Mflv_1210|M.gilvum_PYR-GCK GGLGRYLIDGIKVREFYLALVGALMVTALALILDALLAFAVWASVPGTGR
TH_2403|M.thermoresistible__bu GGIG-----YVAVTYGYQRFDQGVMAATIVILVCTVAVVQLIGDALVRFT
Mvan_3885|M.vanbaalenii_PYR-1 GGVG-----HLAITYGYNRFDDNIMIATVIALIITIQLVQFTGDRVVRAL
MAB_2802c|M.abscessus_ATCC_199 GGLG-----DFAIVQGYQRFNWQVTIVSTVIIIALVQAAQFFGNYLARKA
MSMEG_3057|M.smegmatis_MC2_155 GGLG-----DLAIRYGARSYDGPVLWSTVLLLIVFAQIFQVVGDYFARKT
MLBr_02093|M.leprae_Br4923 ASLPLLIYTELTNPEYAGFL---RVWGAALTLIILVAGINLFG-AAFRFL
MAV_0766|M.avium_104 GTLPGMMYNQASAGAGINPIPTDRLWGAALTLILVIATINIVARVITKFL
MMAR_0033|M.marinum_M GGLGQLITTGIKLQQPVTLIVGAILVAALALFIDWLARLIEMVAAPRGL-
. : : :
Mb3782c|M.bovis_AF2122/97 MRKL------------------AAVVDKPAAGGGHALR-
Rv3756c|M.tuberculosis_H37Rv MRKL------------------AAVVDKPAAGGGHALR-
MUL_4374|M.ulcerans_Agy99 VSRFWHQPD---------DRIDVAVSANSAAVGSHVLR-
Mflv_1210|M.gilvum_PYR-GCK LSRRRAMPQPFLDDEVALESGSPAVRSPVTNGGSRRIR-
TH_2403|M.thermoresistible__bu TPHAR-----------------ARAARV-----------
Mvan_3885|M.vanbaalenii_PYR-1 TR-------------------------------------
MAB_2802c|M.abscessus_ATCC_199 LRR------------------------------------
MSMEG_3057|M.smegmatis_MC2_155 DHRAR-----------------RSAGGAGDAGEAQRLSA
MLBr_02093|M.leprae_Br4923 ATRRCSGCR------------------------------
MAV_0766|M.avium_104 GARKS----------------------------------
MMAR_0033|M.marinum_M ---------------------------------------