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VGKSKQPTLQSIADDLGLHVSTVARVLNGMREGERAASGATAERIRKRAAEVNYRPNPHAASLRTRRTNL VGVLVPRLTDVVLATVYEGIESAAADRGLTAFVANTQDETDRQRNRIDMMLDRRVDGLILGDARSDDHTV LEELTRREVPFVLVNRSVADYPAATCDNYLGGRLAAEHLLALGHRRVGVIAGLAHASTGIDRPAGFVDRF REAGIEVPDEHIVYSGLDSQGGHYAADRMLDGDAPPTAMFAVNDFAAIGAAGAIRNRGLRVGRDVSLIGF NNIALTAEMHVPLTSIESHAFDMGRDALELLADTLAGAAPAQRRTKPVLVVRESTCDAHGSALT
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. smegmatis MC2 155 | MSMEG_2989 | - | - | 100% (344) | LacI family protein transcriptional regulator |
| M. smegmatis MC2 155 | MSMEG_2011 | - | 3e-36 | 32.23% (332) | transcriptional regulator, LacI family protein |
| M. smegmatis MC2 155 | MSMEG_6798 | rbsR | 1e-35 | 28.10% (331) | ribose operon repressor |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb3606c | - | 2e-12 | 25.22% (345) | transcriptional regulatory protein LacI-family |
| M. gilvum PYR-GCK | Mflv_1457 | - | 6e-15 | 27.03% (344) | periplasmic binding protein/LacI transcriptional regulator |
| M. tuberculosis H37Rv | Rv3575c | - | 2e-12 | 25.22% (345) | transcriptional regulatory protein LacI-family |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | - | - | - | - | - |
| M. marinum M | MMAR_5070 | - | 7e-15 | 24.79% (351) | PurR family transcriptional regulator |
| M. avium 104 | MAV_0585 | - | 4e-15 | 24.93% (349) | transcriptional regulator, LacI family protein |
| M. thermoresistible (build 8) | - | - | - | - | - |
| M. ulcerans Agy99 | MUL_4146 | - | 8e-15 | 24.79% (351) | PurR family transcriptional regulator |
| M. vanbaalenii PYR-1 | Mvan_2545 | - | 8e-24 | 29.71% (340) | periplasmic binding protein/LacI transcriptional regulator |
CLUSTAL 2.0.9 multiple sequence alignment
MMAR_5070|M.marinum_M --MSPTPRRRATLASLAAELKVSRSTISNAFN----RPDQLSAELRERVL
MUL_4146|M.ulcerans_Agy99 --MSPTPRRRATLASLAAELKVSRSTISNAFN----RPDQLSVELRERVL
MAV_0585|M.avium_104 --MSPTPRRRATLASLADELKVSRTTVSNAFN----RPDQLSADLRERVL
Mb3606c|M.bovis_AF2122/97 --MSPTPRRRATLASLAAELKVSRTTVSNAFN----RPDQLSADLRERVL
Rv3575c|M.tuberculosis_H37Rv --MSPTPRRRATLASLAAELKVSRTTVSNAFN----RPDQLSADLRERVL
Mflv_1457|M.gilvum_PYR-GCK MSRSPTPRRRATLASLAAELKVSRTTVSNAYN----RPDQLSAELRERVL
Mvan_2545|M.vanbaalenii_PYR-1 ----MIPKQTVNMTDVARRSGVSIASVSRALR----GESGVSAATRDRIL
MSMEG_2989|M.smegmatis_MC2_155 ----MGKSKQPTLQSIADDLGLHVSTVARVLNGMREGERAASGATAERIR
: .: .:* : ::::.. . * :*:
MMAR_5070|M.marinum_M ATAKRMGYPGPDPVARSLRTRKAGAVGLVMAEPLTYFFSDPAARDFVTGV
MUL_4146|M.ulcerans_Agy99 ATAKRMGYPGPDPVARSLRTRKAGAVGLVMAEPLTYFFSDPAARDFVTGV
MAV_0585|M.avium_104 ATAKRLGYPGPDPVARSLRTRKAGAVGLVMAEPLTYFFSDPAARDFVTGV
Mb3606c|M.bovis_AF2122/97 ATAKRLGYAGPDPVARSLRTRKAGAVGLVMAEPLTYFFSDPAARDFVAGV
Rv3575c|M.tuberculosis_H37Rv ATAKRLGYAGPDPVARSLRTRKAGAVGLVMAEPLTYFFSDPAARDFVAGV
Mflv_1457|M.gilvum_PYR-GCK STAKRLGYPGPDPVARSLRTRRAGAVGLVITEPLNYSFSDPAALDFVAGL
Mvan_2545|M.vanbaalenii_PYR-1 SAARELAYVVS-PEASRLSGGPTGRVGVIVPRVDAWFYST-----ILAGI
MSMEG_2989|M.smegmatis_MC2_155 KRAAEVNYRPN-PHAASLRTRRTNLVGVLVPRLTDVVLAT-----VYEGI
* .: * * * * :. **:::.. : . *:
MMAR_5070|M.marinum_M AQSCEELGQGLLLVAVGASRS-LEDGTAAVLNAGVDGFVVYSVR-DDDPY
MUL_4146|M.ulcerans_Agy99 AQSCEELGQGLLLVAVGASRS-LEDGTAAVLNAGVDGFVVYSVR-DDDPY
MAV_0585|M.avium_104 AQSCEALGQGLLLVAVGPSRS-LDEGTAAVLSAGVDGFVVYSVC-DDDPY
Mb3606c|M.bovis_AF2122/97 AQSCEELGQGLQLVSVGSSRS-LADGTAAVLGAGVDGFVVYSVG-DDDPY
Rv3575c|M.tuberculosis_H37Rv AQSCEELGQGLQLVSVGSSRS-LADGTAAVLGAGVDGFVVYSVG-DDDPY
Mflv_1457|M.gilvum_PYR-GCK AESCEAVGQGLLLVAVGPNRS-VAEGSAAVLAAGVDGFVVYSAS-DDDPY
Mvan_2545|M.vanbaalenii_PYR-1 ADEFDTVGMDLILCTLPTSAARHRFFEALPLRRKVDAAVVVSLP-LSARE
MSMEG_2989|M.smegmatis_MC2_155 ESAAADRGLTAFVANTQDETDRQRNRIDMMLDRRVDGLILGDARSDDHTV
. * : . * **. :: . .
MMAR_5070|M.marinum_M LQVVLQRRLPVVVVDQPKELAGVSRVGIDDRAAMRKIADYVLGLGHRQIG
MUL_4146|M.ulcerans_Agy99 LQVVLQRRLPVVVVDQPKELAGVSRVGIDDRAAMRKIADYVLSLGHRQIG
MAV_0585|M.avium_104 LQAVLQRRLPVVVVDQPKGLTGVSRVGIDDRAAMRELADYVLGLGHREIG
Mb3606c|M.bovis_AF2122/97 LQVVLQRRLPVVVVDQPKDLSGVSRVGIDDRAAMRELAGYVLGLGHRELG
Rv3575c|M.tuberculosis_H37Rv LQVVLQRRLPVVVVDQPKDLSGVSRVGIDDRAAMRELAGYVLGLGHRELG
Mflv_1457|M.gilvum_PYR-GCK LPAVMERHLPVVVVDQPRDVPGASQVRIDDRAAMRSLAEHVIDLGHREIG
Mvan_2545|M.vanbaalenii_PYR-1 RTRLDQLAVPTVFVGGHRTEDHRPWVGIDDERAAQQAVGHLLRIGHHDIA
MSMEG_2989|M.smegmatis_MC2_155 LEELTRREVPFVLVN--RSVADYPAATCDNYLGGRLAAEHLLALGHRRVG
: . :* *.*. : . . *: . : . ::: :**: :.
MMAR_5070|M.marinum_M LLTMRLGRDRRQD----LVDAERLKSPTFDVQRERITGVWEAMTAAGVDP
MUL_4146|M.ulcerans_Agy99 LLTMRLGRDRRQD----LVDAERLKSPTFDVQRERITGVWEAMTAAGVDP
MAV_0585|M.avium_104 LLTMRLGRDRRQG----LVDAERLRSPAFDVQRERITGVWEAMTAAGVDP
Mb3606c|M.bovis_AF2122/97 LLTMRLGRDRRQD----LVDAERLRSPTFDVQRERIVGVWEAMTAAGVDP
Rv3575c|M.tuberculosis_H37Rv LLTMRLGRDRRQD----LVDAERLRSPTFDVQRERIVGVWEAMTAAGVDP
Mflv_1457|M.gilvum_PYR-GCK LLTMRLGRDWPHGPGPALADPERVRAPNFHVQCERIHGVYDAMTAAGLDP
Mvan_2545|M.vanbaalenii_PYR-1 MIQAADDTDIPWA-----------------TDQARIRGFHQTMQEAGLAD
MSMEG_2989|M.smegmatis_MC2_155 VIAGLAHAS---------------------TGIDRPAGFVDRFREAGIEV
:: . . * *. : : **:
MMAR_5070|M.marinum_M ESLTVVESYEHLPTSGGDAAKVALEANPRITALMCTADILALSAMDYLRG
MUL_4146|M.ulcerans_Agy99 ESLTVVESYEHLPTSGGDAAKVALEANPRITALMCTADILALSAMDYLRG
MAV_0585|M.avium_104 DSLTVVESYEHLPESGGAAAKVALEANPRITALMCTADILALSAMDYLRA
Mb3606c|M.bovis_AF2122/97 DSLTVVESYEHLPTSGGTAAKVALQANPRLTALMCTADILALSAMDYLRA
Rv3575c|M.tuberculosis_H37Rv DSLTVVESYEHLPTSGGTAAKVALQANPRLTALMCTADILALSAMDYLRA
Mflv_1457|M.gilvum_PYR-GCK ASLTLVESYEHLPTSGGAGADIALEANPRITALMCTADVLALSAMDHLRA
Mvan_2545|M.vanbaalenii_PYR-1 PTVVTVK---WSVDGGSHGMETLLSRSRPPTAVFCHSDEIALGALRTLRR
MSMEG_2989|M.smegmatis_MC2_155 PDEHIVYSG-LDSQGGHYAADRMLDGDAPPTAMFAVNDFAAIGAAGAIRN
* .* . . *. . **::. * *:.* :*
MMAR_5070|M.marinum_M HGIYVPGQMTVTGFD--GVPEAISRGLTTVSQPSLQKGRRAGELLQNPPR
MUL_4146|M.ulcerans_Agy99 HGIYVPGQMTVTGFD--GVPEAISRGLTTVSQPSLQKGRRAGELLQNPPR
MAV_0585|M.avium_104 HGVYVPGQLTVTGFD--GVPDAISRGLTTVSQSSLHKGRRAGELLLKPAR
Mb3606c|M.bovis_AF2122/97 HGIYVPGQMTVTGFD--GVPEALSRGLTTVAQPSLHKGHRAGELLLKPPR
Rv3575c|M.tuberculosis_H37Rv HGIYVPGQMTVTGFD--GVPEALSRGLTTVAQPSLHKGHRAGELLLKPPR
Mflv_1457|M.gilvum_PYR-GCK KGIYVPGQMTVTGFD--GVPEARQRGLTTVAQPGVEKGRRAGELLHNPPR
Mvan_2545|M.vanbaalenii_PYR-1 SGISVPQQVSVIGVD--DHPAAELSDLTTVAQPVREQGRIAARVVLGGLG
MSMEG_2989|M.smegmatis_MC2_155 RGLRVGRDVSLIGFNNIALTAEMHVPLTSIESHAFDMGRDALELLADTLA
*: * :::: *.: . **:: . . *: * .::
MMAR_5070|M.marinum_M SG-----LPVVELLDTELIRGRTAGPPA-----
MUL_4146|M.ulcerans_Agy99 SG-----LPVVELLDTELIRGRTAGPPA-----
MAV_0585|M.avium_104 SG-----LPVVELLDTELIRGRTAGPPA-----
Mb3606c|M.bovis_AF2122/97 SG-----LPVIEVLDTELVRGRTAGPPA-----
Rv3575c|M.tuberculosis_H37Rv SG-----LPVIEVLDTELVRGRTAGPPA-----
Mflv_1457|M.gilvum_PYR-GCK SG-----LPVVEVLDTEVIRGRTSGPPA-----
Mvan_2545|M.vanbaalenii_PYR-1 DGDASGPPASVTTLPTRLVVRGSTAPPR-----
MSMEG_2989|M.smegmatis_MC2_155 GA-----APAQRRTKPVLVVRESTCDAHGSALT
.. . . :: :: .