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MTNNVETPRDTQNESNRATPNLRRTVLASVIGTIAEYYDFFIYGTASALVFNKIFFPEVDPLVGTLAAFS TYAVGFFARPLGGIVWGHVGDRIGRKKALVFTLLLTGFGTFLVGVMPTYQQIGLWAAVVLLVVRLIQGFG VGGEQGGAVLLTAEASPPQRRGFFASFVQLGSPVAYLIPTALFAVLQARMDDETFLSWGWRIPFLLSAIV IVVGLYIRLRVPETEAFRAVKEQGGRRPAPLRTLLADHRREVIGGMAVKFVEAAMFPFYTIFLVTYARSQ NVDPAIVLDAVIIAIVAEVVMVPLWGRLTDRVGRKPVYLGAAVLNLVLLIPAFHAVQTGNFMVIAALLIA GLAVGHAGTYAPQASYFPELFPSSVRYSGVSVVWQFGAMIASGPFTVIAAALLIAGNSSYVWVAVYVAVL ILISIFALVRMPETAVRPRGGTEYADWSN
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. smegmatis MC2 155 | MSMEG_2911 | - | - | 100% (449) | integral membrane transport protein |
| M. smegmatis MC2 155 | MSMEG_2044 | - | e-100 | 43.87% (424) | integral membrane transport protein |
| M. smegmatis MC2 155 | MSMEG_4122 | - | 2e-94 | 41.33% (421) | major facilitator family protein transporter |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb1232 | - | 1e-71 | 37.00% (427) | integral membrane transport protein |
| M. gilvum PYR-GCK | Mflv_1471 | - | 5e-90 | 42.34% (418) | general substrate transporter |
| M. tuberculosis H37Rv | Rv1200 | - | 1e-71 | 37.00% (427) | integral membrane transport protein |
| M. leprae Br4923 | MLBr_01562 | - | 1e-06 | 23.16% (190) | putative transmembrane efflux protein |
| M. abscessus ATCC 19977 | MAB_2481 | - | 2e-89 | 41.35% (416) | putative integral membrane transporter |
| M. marinum M | MMAR_4238 | - | 1e-68 | 37.24% (435) | integral membrane transport protein |
| M. avium 104 | MAV_4627 | - | 6e-90 | 42.22% (424) | major facilitator superfamily protein |
| M. thermoresistible (build 8) | TH_4243 | - | 1e-90 | 42.56% (430) | PUTATIVE General substrate transporter |
| M. ulcerans Agy99 | MUL_0949 | - | 4e-68 | 37.01% (435) | integral membrane transport protein |
| M. vanbaalenii PYR-1 | Mvan_5300 | - | 1e-89 | 42.75% (414) | major facilitator superfamily transporter |
CLUSTAL 2.0.9 multiple sequence alignment
Mb1232|M.bovis_AF2122/97 ----------------------------------------------MKRV
Rv1200|M.tuberculosis_H37Rv ----------------------------------------------MKRV
MMAR_4238|M.marinum_M ----------------------------------------------MSRV
MUL_0949|M.ulcerans_Agy99 ----------------------------------------------MSRV
Mflv_1471|M.gilvum_PYR-GCK ---------------------MSSTGSS----------------TGLKRV
Mvan_5300|M.vanbaalenii_PYR-1 ---------------------MSTQHDARPDG-------PPSITTGLKRV
TH_4243|M.thermoresistible__bu ---------------------VSAPASG------------------LKRV
MSMEG_2911|M.smegmatis_MC2_155 -----------------MTNNVETPRDTQNE--------SNRATPNLRRT
MAB_2481|M.abscessus_ATCC_1997 -----------------MTTTSAVPAVHAGGP-------ADGDAPAARTV
MAV_4627|M.avium_104 -----------------MAATLPAPAPAGLADGHPLDESAEQQRRRLRIV
MLBr_01562|M.leprae_Br4923 MVTLYDHERAVHNWTAARSDRPAPSRLTQQVEPASERTSKYPTLLPSGRF
Mb1232|M.bovis_AF2122/97 ALACLVGSAIEFYDFLIYGTAAALVFPTVFFPHLDP-TVAAVASMGTFAV
Rv1200|M.tuberculosis_H37Rv ALACLVGSAIEFYDFLIYGTAAALVFPTVFFPHLDP-TVAAVASMGTFAV
MMAR_4238|M.marinum_M ALACVVGSTVEYYDFCIYGTAAALVFPAVFYPGLSP-ALATIASMGTFAT
MUL_0949|M.ulcerans_Agy99 ALACVVGSTVEYYDFCIYGTAAALVFPAVFYPGLSP-ALATIASMGTFAT
Mflv_1471|M.gilvum_PYR-GCK VVASMAGTVVEWYEFFLYATAATLVFNKVFFAEGTSEAAGLIAALLTYAV
Mvan_5300|M.vanbaalenii_PYR-1 VVASMAGTVVEWYEFFLYATAATLVFNKVFFAEGTSEAAGLIAALLTYAV
TH_4243|M.thermoresistible__bu VAASMAGTVVEWYEFFLYGTAATLVFNKVFFAQGDNELDAILAAFVTYAV
MSMEG_2911|M.smegmatis_MC2_155 VLASVIGTIAEYYDFFIYGTASALVFNKIFFPEVDP-LVGTLAAFSTYAV
MAB_2481|M.abscessus_ATCC_1997 ALSCMVGTTIEWYDFYLYATAAALVLKPLFFPSVSP-TAGTLASFATYAA
MAV_4627|M.avium_104 VAASLLGTTVEWYDFFLYATAAGLVFNKVFFPNESS-LVGTLLAFATFAV
MLBr_01562|M.leprae_Br4923 PSGRFIAAVIVIGGMQLLATMDSTVA-IVALPKIQNELSLSDAGRSWGIT
. . .: : : .* * : . . .
Mb1232|M.bovis_AF2122/97 AFLSRPFGAAVFG-YFGDRLGRKKTLVATLLIMGLATVTVGLVPTTVAIG
Rv1200|M.tuberculosis_H37Rv AFLSRPFGAAVFG-YFGDRLGRKKTLVATLLIMGLATVTVGLVPTTVAIG
MMAR_4238|M.marinum_M AFLSRPLGAAVFG-HFGDRLGRKKTLVATLLIMALSTVTVGVVPSTATIG
MUL_0949|M.ulcerans_Agy99 AFLSRPLGAAVFG-HFGDRLGRKKTLVATLLIMALSTVTVGVVPSTATIG
Mflv_1471|M.gilvum_PYR-GCK GFVARPLGGVVFG-HFGDKYGRKKLLQFAILLVGVVTFLMGCLPTYNQIG
Mvan_5300|M.vanbaalenii_PYR-1 GFVARPLGGVVFG-HFGDKYGRKKLLQFAILLVGAVTFLMGCLPTYAQIG
TH_4243|M.thermoresistible__bu GFVARPLGGVVFG-HFGDKYGRKKLLQFSILLVGAATFLMGCLPTFGQIG
MSMEG_2911|M.smegmatis_MC2_155 GFFARPLGGIVWG-HVGDRIGRKKALVFTLLLTGFGTFLVGVMPTYQQIG
MAB_2481|M.abscessus_ATCC_1997 GFGARPVGAVIAG-HLGDRVGRKAVLVGALLLMGVATAVIGALPTYSEAG
MAV_4627|M.avium_104 GFVMRPIGGLVFG-HIGDRIGRKRSLALTMLIMGGATALIGVLPTAAQIG
MLBr_01562|M.leprae_Br4923 AYVLTFGGLMLLGGRLGDTIGRKRTFIVGVALFTISSVLCAVA-------
.: * : * .** *** : : : : .
Mb1232|M.bovis_AF2122/97 AAAPLILTTMRLLQGFAVGGEW-AGSALLSAEYAPASKR----GWYGMFT
Rv1200|M.tuberculosis_H37Rv AAAPLILTTMRLLQGFAVGGEW-AGSALLSAEYAPASKR----GWYGMFT
MMAR_4238|M.marinum_M VSAPLILVALRLLQGFAVGGEW-AGSALLSIESAPAHKR----GYYGMFT
MUL_0949|M.ulcerans_Agy99 VSAPLILVALRLLQGFAVGGEW-AGSALLSIESAPAHKR----GYYGMFT
Mflv_1471|M.gilvum_PYR-GCK VWAPILLVVLRFVQGFAVGGEW-GGAVLLVAEHSPAKER----GFWASWP
Mvan_5300|M.vanbaalenii_PYR-1 VWAPILLVVLRFMQGFAVGGEW-GGAVLLVAEHSPNKER----GFWASWP
TH_4243|M.thermoresistible__bu YWAPTLLVLLRFVQGFAVGGEW-GGAVLLVAEHSPNDRR----AFWSSWP
MSMEG_2911|M.smegmatis_MC2_155 LWAAVVLLVVRLIQGFGVGGEQ-GGAVLLTAEASPPQRR----GFFASFV
MAB_2481|M.abscessus_ATCC_1997 VLAPAALATLRVLQGLAAGAEW-GGAALLAVEHAPVGRR----GLFGSFT
MAV_4627|M.avium_104 AWAPVLLLVLRVLQGFALGGEW-GGAVLLAVEHSPGDRR----GRYGAVP
MLBr_01562|M.leprae_Br4923 -WDEVTLVIARLLQGIGSAIASPTGLALVATTFSKGSARNTATAVFAAMT
* *.:**:. . * .*: : * . :.
Mb1232|M.bovis_AF2122/97 VVGGGIALVLTSLTFLG-------VNYTIGESSPTFMQWGWRIPFLVSAA
Rv1200|M.tuberculosis_H37Rv VVGGGIALVLTSLTFLG-------VNYTIGESSPTFMQWGWRIPFLVSAA
MMAR_4238|M.marinum_M VLGGGVALVVSGLTFLG-------VNYTIGESSSAFLQWGWRVPFLLSAL
MUL_0949|M.ulcerans_Agy99 VLGGGVALVVSGLTFLG-------VNYTIGESSSALLQWGWRVPFLLSAL
Mflv_1471|M.gilvum_PYR-GCK QAAVPVGNMLATVVLLV-------LTGVLP--EAAFMSWGWRIAFWLSAV
Mvan_5300|M.vanbaalenii_PYR-1 QAAVPVGNMLATVVLLV-------LTGTLS--NDAFLSWGWRVAFWLSAV
TH_4243|M.thermoresistible__bu QAAVPVGNMLATVVLLV-------LTTTLP--ESAFLSWGWRVAFWLSAV
MSMEG_2911|M.smegmatis_MC2_155 QLGSPVAYLIPTALFAV-------LQARMD--DETFLSWGWRIPFLLSAI
MAB_2481|M.abscessus_ATCC_1997 QLGSPAGMLLATGVFGL-------TRALTG--PEAFLAFGWRIPFLSSIV
MAV_4627|M.avium_104 QVGLALGLALGTGIFAF-------LQIVLG--PARFLSYGWRIGFLLSVL
MLBr_01562|M.leprae_Br4923 AIGSVMGLVVGGALTEVSWRLAFLVNVPIGLVMIYLARTALHETHKERMK
. . : : . : .
Mb1232|M.bovis_AF2122/97 LIAVALYVRFNIDETPVFAR--ERADEKTRLGPAETPIAQVLRRQR----
Rv1200|M.tuberculosis_H37Rv LIAVALYVRFNIDETPVFAR--ERADEKTRLGPAETPIAQVLRRQR----
MMAR_4238|M.marinum_M LIAFALYVRLEINETPVFARAMAQADDQESTAAARAPLAAVLCRQR----
MUL_0949|M.ulcerans_Agy99 LIAFALYVRLEINETPVFARAMAQADDQESTAAARAPLAAVLCRQR----
Mflv_1471|M.gilvum_PYR-GCK VVLIGYYIRTKVTDAPIFVAAQEEVE---RTKAVSYGVVEVLKRYP----
Mvan_5300|M.vanbaalenii_PYR-1 VVLVGYYIRTKVTDAPIFVAAQEEVE---RVKSVSYGVVEVLKRYP----
TH_4243|M.thermoresistible__bu VVLIGYYIRTKVSDAPIFLAVQQEVE---QARSTSYGVVEVLRRYP----
MSMEG_2911|M.smegmatis_MC2_155 VIVVGLYIRLRVPETEAFRAVKEQGG---RRPAP---LRTLLADHR----
MAB_2481|M.abscessus_ATCC_1997 LVVVGLAIRLRLRDSVVFRKVLERGE---AARLP---VVEVLRTQS----
MAV_4627|M.avium_104 LVAIGIVVRLRVEETPAFRELQDLQA---ASTVP---IRDILRERRS---
MLBr_01562|M.leprae_Br4923 LDAAGAILATLACTAAVFAFSMGPEKGWISLTTIGSGLVALVAAIAFAVV
: . : : * : ::
Mb1232|M.bovis_AF2122/97 ----------------REIVLAAGSAVCCFGFVYLASTYLASYAQTRLGY
Rv1200|M.tuberculosis_H37Rv ----------------REIVLAAGSAVCCFGFVYLASTYLASYAQTRLGY
MMAR_4238|M.marinum_M ----------------REIVLAAGAMLAAFGCLYLASTFLPSYAQLHLGY
MUL_0949|M.ulcerans_Agy99 ----------------REIVLAAGAMLAAFGCLYLASTFLPSYAQLHLGY
Mflv_1471|M.gilvum_PYR-GCK ----------------RGVFTAMGLRFAENIMYYLVVTFSIVYLKNHVGA
Mvan_5300|M.vanbaalenii_PYR-1 ----------------RGVFTAMGLRFAENIMYYLVVTFSIVYLKTHVGA
TH_4243|M.thermoresistible__bu ----------------RGVLTAMGLRFAENIMYYLVVTFSITYLKVHVGA
MSMEG_2911|M.smegmatis_MC2_155 ----------------REVIGGMAVKFVEAAMFPFYTIFLVTYARSQN-V
MAB_2481|M.abscessus_ATCC_1997 ----------------RNVLLTTGLRLSQIALFVLLTTFSLTYLQGSFGG
MAV_4627|M.avium_104 ---------------RRNTVLGLLSRWAEGSAFNTWGVFAISYATGALGL
MLBr_01562|M.leprae_Br4923 ERTAENPVVPFDLFRDRNRLVTFIAIFLAGGVIFSLTVSIGLYIQDILGY
* . *
Mb1232|M.bovis_AF2122/97 SRGSILFDSVLGGLLCIVFTALSSALCDQLGRRRVLLAGWAVALPWSLLV
Rv1200|M.tuberculosis_H37Rv SRGSILFDSVLGGLLCIVFTALSSALCDQLGRRRVLLAGWAVALPWSLLV
MMAR_4238|M.marinum_M SRNLVLLIGVLGGLVCIGFVALSAILCDRFGRRRVMLVGWAVGLFWSPLV
MUL_0949|M.ulcerans_Agy99 SRNLVLLIGVLGGLVCIGFVALSAILCDRFGRRRVMLVGWAVGLFWSPLV
Mflv_1471|M.gilvum_PYR-GCK DTSDILWWLLAAHAVHFLVVPQVGRLSDRFGRRPVYIVGAILAATWGFFA
Mvan_5300|M.vanbaalenii_PYR-1 DTSDILWWLLAAHAVHFLVVPQVGRLADRFGRRPVYIAGAMLAATWGFFA
TH_4243|M.thermoresistible__bu DTSDILWYLMAAHAVHFVAIPTVGRLADEFGRRPVYLVGTLAAGAWGFIA
MSMEG_2911|M.smegmatis_MC2_155 DPAIVLDAVIIAIVAEVVMVPLWGRLTDRVGRKPVYLGAAVLNLVLLIPA
MAB_2481|M.abscessus_ATCC_1997 DSQIGLTAVLISSALGILSTPVWSALSDRVGRRPLYLFGSAAGPLALGLF
MAV_4627|M.avium_104 NRVSVLIAVTIAALLMAVLLPVSGVLTDRFGARRVYLAGIACYGLAAFPA
MLBr_01562|M.leprae_Br4923 SALRAGIGFIPFVIAMGIGLGVSSQLVSRFSPRVLTIGGGWLLMVAMLYG
. . * .... : : : .
Mb1232|M.bovis_AF2122/97 MPLIDSGS---PSLFAVAVVG-MYAIGGFGFGPTASFIPELFATSYRYTG
Rv1200|M.tuberculosis_H37Rv MPLIDSGS---PSLFAVAVVG-MYAIGGFGFGPTASFIPELFATSYRYTG
MMAR_4238|M.marinum_M MPLIGSGD---TVGFTVALLG-LYAVAASGFGPAASLIPELFATRYRYTG
MUL_0949|M.ulcerans_Agy99 MPLIGSGD---TVGFTVALLG-LYAVAASGFGPAASLIPELFATRYRYTG
Mflv_1471|M.gilvum_PYR-GCK FPMMNTGS---YLLIMGAVILGLMI-HALMYAPQPAIMAEMFPTRMRYSG
Mvan_5300|M.vanbaalenii_PYR-1 FPMMNSGD---YLLILGAVILGLMI-HALMYAPQPAIMAEMFPTRMRYSG
TH_4243|M.thermoresistible__bu FPMMNSAN---YVIITGAVVLGLIA-HAFMYAPQPALMAEMFPTRMRYSG
MSMEG_2911|M.smegmatis_MC2_155 FHAVQTGN---FMVIAALLIAGLAVGHAGTYAPQASYFPELFPSSVRYSG
MAB_2481|M.abscessus_ATCC_1997 FLAAGSGS---KVLVVLSIVFGINVVHDAMYGPQAAWFAELFDTRVRYSG
MAV_4627|M.avium_104 FALFGTKK---LLWFGLAMVIVFGVVHALFYGAQGTLYSALYPTNTRYTG
MLBr_01562|M.leprae_Br4923 WAFMNRGVPYFPNLLAPIVVGGIGIGMAVVPLTLSAIAGVGFDRIGPVSA
. :: : . : : :.
Mb1232|M.bovis_AF2122/97 SALAANLAG------------------VAGG-ALPPVIAGALVAT--YGS
Rv1200|M.tuberculosis_H37Rv SALAANLAG------------------VAGG-ALPPVIAGALVAT--YGS
MMAR_4238|M.marinum_M TALALNVAG------------------IVGG-AAPPLIAGTLLAS--YGS
MUL_0949|M.ulcerans_Agy99 TALALNVAG------------------IVGG-AAPPLIAGTLLAS--YGS
Mflv_1471|M.gilvum_PYR-GCK VSLGYQVTS------------------IVAG-SLAPAIATWLLDK-FGTW
Mvan_5300|M.vanbaalenii_PYR-1 VSLGYQVTS------------------IVAG-SLAPAIATWLLDR-FGTW
TH_4243|M.thermoresistible__bu VSVGYQVTA------------------IVAG-SMAPIIAVRLLDV-YSSA
MSMEG_2911|M.smegmatis_MC2_155 VSVVWQFGA------------------MIASGPFTVIAAALLIAG-NSSY
MAB_2481|M.abscessus_ATCC_1997 ASLGYQIGA------------------VLSG-GFAPLIAAALLAANHGDP
MAV_4627|M.avium_104 LSFVYQFSG------------------VYAS-GVTPMILTALIAALGGAP
MLBr_01562|M.leprae_Br4923 IALMLQSLGGPLVLAVIQAVITSRTLYLGGTTGPVKFMNDAQLRALDHGY
:. : . : . :
Mb1232|M.bovis_AF2122/97 WAIGVMLAILALISLVCTYRLPETAGSALVSR------------------
Rv1200|M.tuberculosis_H37Rv WAIGVMLAILALISLVCTYRLPETAGSALVSR------------------
MMAR_4238|M.marinum_M SAVGLMMTALVAASLLCTYLLPETAGAPLTAA------------------
MUL_0949|M.ulcerans_Agy99 SAVGLMMTALVAASLLCTYLLPETAGAPLTAA------------------
Mflv_1471|M.gilvum_PYR-GCK VPIALYLAGAAVITLVAAWFTRETKGIDLHALDVADREQLEKAGIV----
Mvan_5300|M.vanbaalenii_PYR-1 VPIAVYLAGAAVITLVAAWFTRETNGIDLHSLDVADREQLAKAGIV----
TH_4243|M.thermoresistible__bu VPIALYLAGAAVVTLIALAFTRETNGIDLAGVDRADAEESARXXPTTTDR
MSMEG_2911|M.smegmatis_MC2_155 VWVAVYVAVLILISIFALVRMPETAVRPRGGTEYADWSN-----------
MAB_2481|M.abscessus_ATCC_1997 RLIVCYYLALSVLTFGAACVARETYRDQIGDSL-----------------
MAV_4627|M.avium_104 WLACGYLVATAVISVLATALIRDRDLYL----------------------
MLBr_01562|M.leprae_Br4923 TYGLLWVAGAVVIVGVAALFIGYTPEQVAYAQEVKEAVDAGEL-------
.
Mb1232|M.bovis_AF2122/97 --------------------------------------------------
Rv1200|M.tuberculosis_H37Rv --------------------------------------------------
MMAR_4238|M.marinum_M --------------------------------------------------
MUL_0949|M.ulcerans_Agy99 --------------------------------------------------
Mflv_1471|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_5300|M.vanbaalenii_PYR-1 --------------------------------------------------
TH_4243|M.thermoresistible__bu PAQCPGVPVCRRLRSSGPRARRRTERCWRTPGIQPAVRPTRSPTPGPSAA
MSMEG_2911|M.smegmatis_MC2_155 --------------------------------------------------
MAB_2481|M.abscessus_ATCC_1997 --------------------------------------------------
MAV_4627|M.avium_104 --------------------------------------------------
MLBr_01562|M.leprae_Br4923 --------------------------------------------------
Mb1232|M.bovis_AF2122/97 ----------------------
Rv1200|M.tuberculosis_H37Rv ----------------------
MMAR_4238|M.marinum_M ----------------------
MUL_0949|M.ulcerans_Agy99 ----------------------
Mflv_1471|M.gilvum_PYR-GCK ----------------------
Mvan_5300|M.vanbaalenii_PYR-1 ----------------------
TH_4243|M.thermoresistible__bu RTRRAAPVTRSAGSAATIRRSR
MSMEG_2911|M.smegmatis_MC2_155 ----------------------
MAB_2481|M.abscessus_ATCC_1997 ----------------------
MAV_4627|M.avium_104 ----------------------
MLBr_01562|M.leprae_Br4923 ----------------------