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MTAPKQGTNRERVYAELRRQIVTLALAPGASLSENELAAQLSVSRTPVRESLILLADEGLVQIFPKLGSF VARIDPERVADAQFIREAIELANIPQAVERADRAAIAELRALIAAQRETTDVNTFFELDEQFHRCLLATG GHANAWRTVVAAKAHLDRARRLGMLSESSIQSLTDEHAAIVDAVDGGDGDKATAALRDHLRKVFTDIEKI RSRSPELFADGATARPTRRVVAVWQ
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. smegmatis MC2 155 | MSMEG_2910 | - | - | 100% (235) | transcriptional regulator, GntR family protein |
| M. smegmatis MC2 155 | MSMEG_0535 | - | 1e-18 | 28.64% (206) | GntR-family protein transcriptional regulator |
| M. smegmatis MC2 155 | MSMEG_6639 | - | 1e-16 | 30.93% (194) | transcriptional regulator, GntR family protein, putative |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb0170c | - | 4e-08 | 29.92% (127) | GntR family transcriptional regulator |
| M. gilvum PYR-GCK | Mflv_0958 | - | 6e-16 | 31.22% (205) | GntR family transcriptional regulator |
| M. tuberculosis H37Rv | Rv0165c | - | 5e-08 | 29.92% (127) | GntR family transcriptional regulator |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | MAB_0068 | - | 8e-17 | 29.72% (212) | GntR family transcriptional regulator |
| M. marinum M | MMAR_0408 | - | 6e-12 | 29.50% (200) | GntR family transcriptional regulator |
| M. avium 104 | MAV_0339 | - | 1e-18 | 32.99% (194) | transcriptional regulator, GntR family protein |
| M. thermoresistible (build 8) | TH_3038 | - | 8e-15 | 28.43% (204) | PUTATIVE putative transcriptional regulator, GntR family |
| M. ulcerans Agy99 | MUL_1058 | - | 2e-12 | 29.50% (200) | GntR family transcriptional regulator |
| M. vanbaalenii PYR-1 | Mvan_0931 | - | 4e-13 | 24.89% (229) | GntR family transcriptional regulator |
CLUSTAL 2.0.9 multiple sequence alignment
Mb0170c|M.bovis_AF2122/97 MIKHDVVWVTLWPERPNNKPPPSPRQVPGNPGPTLKVLASHVNAPLSAKP
Rv0165c|M.tuberculosis_H37Rv MIKHDVVWVTLWPERPNNKPPPSPRQVPGNPGPTLKVLASHVNAPLSAKP
MMAR_0408|M.marinum_M -----------------------------------------MNIPLSARR
MUL_1058|M.ulcerans_Agy99 -----------------------------------------MNILLSARR
MAV_0339|M.avium_104 ---------------------------------------------MAAID
MSMEG_2910|M.smegmatis_MC2_155 ---------------------------------------------MTAPK
MAB_0068|M.abscessus_ATCC_1997 --------------------------------------------MIRTVA
Mflv_0958|M.gilvum_PYR-GCK -------------------------------------------MADAQLQ
TH_3038|M.thermoresistible__bu ---------------------------------------------MSRTV
Mvan_0931|M.vanbaalenii_PYR-1 ----------------------------------------MPHRRHSVLL
Mb0170c|M.bovis_AF2122/97 RSQLPLRRAQLSDEVAGHLRAAIMSGALRSGTFIRLDETAAELGVSVTPV
Rv0165c|M.tuberculosis_H37Rv RSQLPLRRAQLSDEVAGHLRAAIMSGALRSGTFIRLDETAAELGVSVTPV
MMAR_0408|M.marinum_M KSRRPLRRAQLSDEVAGHLRAAIMSGTLRPGTFIRLDETAAELGVSITPV
MUL_1058|M.ulcerans_Agy99 ESRRPLRRAQLSDEVAGHLRAAIMSGTLRPGTFIRLDETAAELGVSITPV
MAV_0339|M.avium_104 ISG------TVRERAARELRDRILTGALPAGSRIDLDAITAEFATSRTPV
MSMEG_2910|M.smegmatis_MC2_155 QGTN-------RERVYAELRRQIVTLALAPGASLSENELAAQLSVSRTPV
MAB_0068|M.abscessus_ATCC_1997 ISAS--------EEAYRSVKESILNGDIPGGELLSEGEISARMGCSRTPV
Mflv_0958|M.gilvum_PYR-GCK LAALPAAEGRRAEQVMAAVRAALDAGVMRPGVKYSVYQLADALQVSRTPV
TH_3038|M.thermoresistible__bu ESNG-----DASERAYQAVLQMILDGEAPAGSWLREQTLAEQIGVSRTPV
Mvan_0931|M.vanbaalenii_PYR-1 GSLTVERPGGSQQVILDELRRAILDGAVPPGTPIPLAEVAEHFGVSRIPV
. : : : * : : * **
Mb0170c|M.bovis_AF2122/97 REALLKLRGEGMVGLEPHRGHVVLPLTRQDIDDIFWLQATIAQELATSAT
Rv0165c|M.tuberculosis_H37Rv REALLKLRGEGMVGLEPHRGHVVLPLTRQDIDDIFWLQATIAQELATSAT
MMAR_0408|M.marinum_M REALLKLRGEGMVQLEPHRGHVVLPLTRQDIDDIFWLQATIARELAVTAT
MUL_1058|M.ulcerans_Agy99 REALLKLRGEGMVQLEPHRGHVVLPLTRQDIDDIFWLQATIARELAVTAT
MAV_0339|M.avium_104 REALLELSFEGLVQVAPRSGVTVIGISPEDVLDSFTILGVLTGQAAAWAA
MSMEG_2910|M.smegmatis_MC2_155 RESLILLADEGLVQIFPKLGSFVARIDPERVADAQFIREAIELANIPQAV
MAB_0068|M.abscessus_ATCC_1997 REAFLRLETEGWLRLYPKRGALVVPITPEERRHVVDARRVIEGAAAARIA
Mflv_0958|M.gilvum_PYR-GCK RDALLRLEEIGLIRFEARQGFRILLPDPREIADIVAIRFALEPPAAGRAA
TH_3038|M.thermoresistible__bu RQALNRLAAEGAIELVPNRGAQVVSFSDEDVEALFDLRARFEPLAVRLAV
Mvan_0931|M.vanbaalenii_PYR-1 RESLKTLIGEGLVAHRANSGYMVAQLTAAELGELYVARESLEAASLAAAV
*::: * * : .. * : : .
Mb0170c|M.bovis_AF2122/97 AH-ITDVEIDELDRINNALAGAIGSG--DAKTIASIEFAFHRVFNKASRR
Rv0165c|M.tuberculosis_H37Rv AH-ITDVEIDELDRINNALAGAIGSG--DAKTIASIEFAFHRVFNKASRR
MMAR_0408|M.marinum_M ER-ISEIDIGELEHINDALTAAVGAG--DTEAIAALEFAFHRVLNQSSGR
MUL_1058|M.ulcerans_Agy99 ER-ISEVVIGELEHINDALTAAVGAG--DTEAIAALEFAFHRVLNQSSGR
MAV_0339|M.avium_104 ER-IGPEELATLRELAAEVVAKSGD-----DSIGEANWHFHQMIHRAAHS
MSMEG_2910|M.smegmatis_MC2_155 ER-ADRAAIAELRAL---IAAQRETT--DVNTFFELDEQFHRCLLATGGH
MAB_0068|M.abscessus_ATCC_1997 ERGAPQSLLSDLSALIEVQLGRAAQG--DAAGFAAADVDFHRAIVAKLGN
Mflv_0958|M.gilvum_PYR-GCK AV-CGPPLADRLAERMELLRRAAARG--DEPGFAAHDLLLHDHILEAAGN
TH_3038|M.thermoresistible__bu PQ-LTEERIAELADLATRMEALLDRRPLDTHQMSRLNNAFHGIFLAEAGN
Mvan_0931|M.vanbaalenii_PYR-1 GN-ASEADFATAIDMNALLEHAIRED--DAVAYHRQSRRFHAALTGPSRM
. :* :
Mb0170c|M.bovis_AF2122/97 IKLAWFLLNAARYMP---AQVFAADPRWGADAVNSHRQLIAALRRRDTAA
Rv0165c|M.tuberculosis_H37Rv IKLAWFLLNAARYMG---AGVRGRP----AMGRGRGEQSSAADRR---AA
MMAR_0408|M.marinum_M IKLAWFLLNAARYMP---AQLYASDPQWGAAAVDNHRQLIAALRRRDTAA
MUL_1058|M.ulcerans_Agy99 IKLAWFLLNAARYMP---AQLYASDPQWGAAAVDNHRQLIAALRRRDTAA
MAV_0339|M.avium_104 PRLANQIKHAARVVP---TNFLTLFPEHEKHSLDEHAQLLDALGDKDVER
MSMEG_2910|M.smegmatis_MC2_155 ANAWRTVVAAKAHLDRA-RRLGMLSESSIQSLTDEHAAIVDAVDGGDGDK
MAB_0068|M.abscessus_ATCC_1997 PLLENFYDSLRERQRRMAAAAIGVDPVRVARSVAGHRALVDALAAGDAAR
Mflv_0958|M.gilvum_PYR-GCK NRARRIVRSLRESTR-LLGGITADRSRTMSDIDAEHQPVVDAVIANDPAA
TH_3038|M.thermoresistible__bu RHLTAAMQAVVRPALVT-LTFQKYSERALRLSMHHHAELVEAARARDPEW
Mvan_0931|M.vanbaalenii_PYR-1 YRLLRMLETAWNLTEP-VQPMVHVTPDDRIRLHADHGEMLQAFLTRDVER
*
Mb0170c|M.bovis_AF2122/97 VIEHTVWQFTDGARRLTEALAETEVFG------------------
Rv0165c|M.tuberculosis_H37Rv PPRHSRR---NRAHRLAVHRWGTQADGGPG---------------
MMAR_0408|M.marinum_M VIEHSVWQFTDAAHRLTQMLETNGIFN------------------
MUL_1058|M.ulcerans_Agy99 VIEHSVWQFTDAAHRLTQMLETNGIFN------------------
MAV_0339|M.avium_104 ARAIAERHVLDAGRSLAEWLEQRRDGER-----------------
MSMEG_2910|M.smegmatis_MC2_155 ATAALRDHLRKVFTDIEKIRSRSPELFADGATARPTRRVVAVWQ-
MAB_0068|M.abscessus_ATCC_1997 FSTELVEHMKVVTEVD-----------------------------
Mflv_0958|M.gilvum_PYR-GCK AAAAMRTHLTSTGRLLVAQAVRDQDSPLDAAAVWAEAVGANTELP
TH_3038|M.thermoresistible__bu AEAVMRAHILAARHAGE----------------------------
Mvan_0931|M.vanbaalenii_PYR-1 LLGAAERHARRLNSVIATLSFETGLLAAEKDISSPQ---------