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AIETGSTSGPVTTGEGQRTLESFGYKQELSRQISTVDLIVYGLVFMVPIAPWTIFGTVYNSASGMVPLVY LIGLIAMVFTALAYAQMAKSFPLAGSVFAYVGRGIHPGLGFFAGWAMLLDYLLIPTLLYVFAAESMVGLF PGTPRWVWAVVFVAVNTVINLLGVSSLKIVNRLFLAVELVFVVLFIIIAVRAINGQSLPDVRWSTLPIWN SELVTAPLLAAALSIAVLSFLGFDGISTLAEESTGKKNPAGRAMIVSLFIVAFLFITQTWLASLLAGGRE AFSDDEAGNAFFTLVQAASSTGWMNAFFVVNVLAVGFANAMAAQAATSRLLFSMSRDRQLPAFLSKISSR KVPVAALLVVSALSLVLVLFFVGQIGLISSLVNFGALFGFCLLHASVIWFYLVRNKSTNYLLHGVVPTIG FLIIGYVLINADSLAKIGGISWLVIGAIVFGVNNVRGRGVPTLTEAA*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. smegmatis MC2 155 | MSMEG_2680 | - | - | 100% (468) | amino acid transporter |
| M. smegmatis MC2 155 | MSMEG_0446 | - | 1e-66 | 33.41% (443) | putrescine importer |
| M. smegmatis MC2 155 | MSMEG_1838 | - | 1e-25 | 23.25% (456) | cationic amino acid transporter |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb3281c | - | 8e-24 | 23.52% (455) | cationic amino acid transport integral membrane protein |
| M. gilvum PYR-GCK | Mflv_3442 | - | 1e-25 | 27.40% (427) | ethanolamine transproter |
| M. tuberculosis H37Rv | Rv3253c | - | 8e-24 | 23.52% (455) | cationic amino acid transport integral membrane protein |
| M. leprae Br4923 | MLBr_01974 | - | 5e-16 | 22.33% (421) | putative permease |
| M. abscessus ATCC 19977 | MAB_3599c | - | 2e-26 | 24.34% (456) | putative amino acid permease |
| M. marinum M | MMAR_0869 | - | 8e-58 | 32.10% (433) | amino acid permease |
| M. avium 104 | MAV_4216 | - | 1e-24 | 23.64% (478) | cationic amino acid transporter |
| M. thermoresistible (build 8) | TH_0471 | - | 9e-28 | 24.31% (473) | POSSIBLE CATIONIC AMINO ACID TRANSPORT INTEGRAL MEMBRANE |
| M. ulcerans Agy99 | MUL_2597 | - | 8e-25 | 24.46% (462) | cationic amino acid transport integral membrane protein |
| M. vanbaalenii PYR-1 | Mvan_3196 | - | 3e-28 | 27.87% (427) | ethanolamine transproter |
CLUSTAL 2.0.9 multiple sequence alignment
Mb3281c|M.bovis_AF2122/97 --------------------------------------------------
Rv3253c|M.tuberculosis_H37Rv --------------------------------------------------
MUL_2597|M.ulcerans_Agy99 --------------------------------------------------
MAV_4216|M.avium_104 --------------------------------------------------
TH_0471|M.thermoresistible__bu --------------------------------------------------
MAB_3599c|M.abscessus_ATCC_199 --------------------------------------------------
Mflv_3442|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_3196|M.vanbaalenii_PYR-1 --------------------------------------------------
MMAR_0869|M.marinum_M --------------------------------------------------
MSMEG_2680|M.smegmatis_MC2_155 --------------------------------------------------
MLBr_01974|M.leprae_Br4923 MFLSADVSCIEIVDINCSELRNDRRIPPQLALFCTNAANKAESAVTSHGQ
Mb3281c|M.bovis_AF2122/97 ---MAGR----RRMKSVEQS-IADTDEPTTRLRKDLT-------------
Rv3253c|M.tuberculosis_H37Rv ---MAGR----RRMKSVEQS-IADTDEPTTRLRKDLT-------------
MUL_2597|M.ulcerans_Agy99 ---MAGG----LRTKSVEQS-IADTDEPETRLRKDLT-------------
MAV_4216|M.avium_104 ---MASR----WRTKSVEQS-IADTDEPDTRLRKDLT-------------
TH_0471|M.thermoresistible__bu ---MTDR----LRVKSVEQS-IADTDEPDSRLRKDLS-------------
MAB_3599c|M.abscessus_ATCC_199 ---MPGSGL--WRTKSVEQS-IADTDEPETKLRRDLT-------------
Mflv_3442|M.gilvum_PYR-GCK -------------MRGVEEHRESESYLQKRQLKSGSAG------------
Mvan_3196|M.vanbaalenii_PYR-1 ---MSGEAHSTHTTRGVEAHRESDAYLQKRQLKKGSAG------------
MMAR_0869|M.marinum_M ---------------------MAVTTGARSELQKALG-------------
MSMEG_2680|M.smegmatis_MC2_155 --MAIETGSTSGPVTTGEGQRTLESFGYKQELSRQIS-------------
MLBr_01974|M.leprae_Br4923 LPIMANRRWAPHTRRQSGRATSTCSSLMRFSASESRAHSRFECYTLVRWS
:
Mb3281c|M.bovis_AF2122/97 -------------WWDLVVFGVSVVIGAGIFTVTASTAGDITGPAIWISF
Rv3253c|M.tuberculosis_H37Rv -------------WWDLVVFGVSVVIGAGIFTVTASTAGDITGPAIWISF
MUL_2597|M.ulcerans_Agy99 -------------WRDLVVFGVSVVIGAGIFTVTASTAGDITGPAIWISF
MAV_4216|M.avium_104 -------------WWDLVVFGVAVVIGAGIFTVTASTTGDITGPAIWVSF
TH_0471|M.thermoresistible__bu -------------WWDLTVFGVSVVIGAGIFTVTASTAGNITGPAISVSF
MAB_3599c|M.abscessus_ATCC_199 -------------WWDLTVFGVSVVIGAGIFTVTASTAANVTGPAISLSF
Mflv_3442|M.gilvum_PYR-GCK -------------WILLAGLGVSYVISGDYSGWNFGLGQGGFG-GLAIAA
Mvan_3196|M.vanbaalenii_PYR-1 -------------WILLAGLGISYVVSGDYSGWNFGLGQGGFG-GLAIAA
MMAR_0869|M.marinum_M -------------QRSAVLFGLAYMTPIIVLGIFGVIAERSKG-ASAGSY
MSMEG_2680|M.smegmatis_MC2_155 -------------TVDLIVYGLVFMVPIAPWTIFGTVYNSASG-MVPLVY
MLBr_01974|M.leprae_Br4923 IRGQGGRAISKLGFWSVVMLGINSIIGAGIFMTPGEVIK-IAGPFAPIAY
*: : *
Mb3281c|M.bovis_AF2122/97 LIAAATCALAALCYAEFASTLPVAGSAYTFSYATFGEFLAWVIGWNLVLE
Rv3253c|M.tuberculosis_H37Rv LIAAATCALAALCYAEFASTLPVAGSAYTFSYATFGEFLAWVIGWNLVLE
MUL_2597|M.ulcerans_Agy99 LIAAGTCALAALCYAEFASTLPVAGSAYTFSYATFGEFLAWVIGWNLVLE
MAV_4216|M.avium_104 VIAAGTCALAALCYAEFASTLPVAGSAYTFSYATFGEFLAWIIGWNLLLE
TH_0471|M.thermoresistible__bu IIAAIACGLAALCYAEFASTVPVAGSAYTFSYATFGEFVAWIIGWDLILE
MAB_3599c|M.abscessus_ATCC_199 IMAAIGCGLAAMCYAEFASTIPVAGSAYTFSYATFGEFAAWILGWDLILE
Mflv_3442|M.gilvum_PYR-GCK VIIAAMYLAMVLGMAEMSSALPAAGGGYTFARRALGPWGGFATGTAILIE
Mvan_3196|M.vanbaalenii_PYR-1 VVIAAMYLAMVLGMAEMSSALPAAGGGYTFARRALGPWGGFATGTAILIE
MMAR_0869|M.marinum_M LLATVAMLFTAQSYGVMARHFPVAGSAYTYVRKALDARVGFMVGWAVLLD
MSMEG_2680|M.smegmatis_MC2_155 LIGLIAMVFTALAYAQMAKSFPLAGSVFAYVGRGIHPGLGFFAGWAMLLD
MLBr_01974|M.leprae_Br4923 TLAGIFAAVLAIVFATAAKYVKTNGSSYAYTTAAFGHRIGIYVGVTHAIT
: . . : . *. ::: : . * :
Mb3281c|M.bovis_AF2122/97 LAMGAAVVAKGWSSYLGTVFGFGNGTG--HLGSLQLDWGALVIVTLVATL
Rv3253c|M.tuberculosis_H37Rv LAMGAAVVAKGWSSYLGTVFGFGNGTG--HLGSLQLDWGALVIVTLVATL
MUL_2597|M.ulcerans_Agy99 LAIGAAVVAKGWSSYLGTVFGFSGGTA--DFGSIRLDWGALLSVSIVSLL
MAV_4216|M.avium_104 LAIGAAVVAKGWSSYLGTVFGFSGGTV--KFGAAQLDWGALVIVGGVATL
TH_0471|M.thermoresistible__bu FSVAAAVVAKGWSSYLGEVFEFAGATT--RLGPITLDWGALLIIGFVTVL
MAB_3599c|M.abscessus_ATCC_199 FSVGAATVAKGWSSYLSTVFGLSSGAV--HLGAVKIDWGALLIVSVLTVL
Mflv_3442|M.gilvum_PYR-GCK YAIAPAAIATFIGAYVESLN---------LFGITDGWWVYLAAYALFIGI
Mvan_3196|M.vanbaalenii_PYR-1 YSIAPAAIATFIGAYVESLG---------LFGITDGWWVYLAAYAIFIGI
MMAR_0869|M.marinum_M YLFLPLVIWLIGGSYLQDRFP-----------TVPFWTWIVGFAALTTVL
MSMEG_2680|M.smegmatis_MC2_155 YLLIPTLLYVFAAESMVGLFP-----------GTPRWVWAVVFVAVNTVI
MLBr_01974|M.leprae_Br4923 ASIAWGVLASSFVSTLLRVAFPEKIWADNDELISVKTLTFLVFIAVLLAI
. : : : :
Mb3281c|M.bovis_AF2122/97 IALGTKLSSRFSAVVTAIKVSVVVLVVVVGAFYIRAANYSPFIPEPEVQH
Rv3253c|M.tuberculosis_H37Rv IALGTKLSSRFSAVVTAIKVSVVVLVVVVGAFYIRAANYSPFIPEPEVQH
MUL_2597|M.ulcerans_Agy99 VAYGTKLSSRFSAVVTTIKVAVVILVVVVGAFYVKAANYSPFIPEPEAGP
MAV_4216|M.avium_104 IALGTKLSSRFSAVITGIKVSVVVFVVVVGVFYIKRANYSPFIPKPEAGG
TH_0471|M.thermoresistible__bu LATGTKLSANVSLAITVIKVGVVLLVVIVGAFFIKAANYTPFIPPAEAGG
MAB_3599c|M.abscessus_ATCC_199 LAVGTKLSSRVSLVITTIKVLVVLLVIIVGAFFIKTANYTPFIPPAEAGS
Mflv_3442|M.gilvum_PYR-GCK HLAGVGEALKVMFVITVIALIGIVVFAVAAIPQFDSANLTDIAVTDAAGA
Mvan_3196|M.vanbaalenii_PYR-1 HLSGVGEALKVMFVITAIALVGLVVFAVAAIPHFDSTNLTDIAVTDAAGA
MMAR_0869|M.marinum_M NLIGLKVADRANFILMTFQLLILAFFVALTIGYLVGDSRSLLSLTPFTGN
MSMEG_2680|M.smegmatis_MC2_155 NLLGVSSLKIVNRLFLAVELVFVVLFIIIAVRAINGQSLPDVRWSTLPIW
MLBr_01974|M.leprae_Br4923 NIFGNLVIRWANGISALGKIFALSVFIAGGLWTIITQHVNNYVTSRSAYQ
* : : .. .
Mb3281c|M.bovis_AF2122/97 HG-GGLDQSVFSLLTGAQGSHYGWYGVLAGASIVFFAFIGFDIVATMAEE
Rv3253c|M.tuberculosis_H37Rv HG-GGLDQSVFSLLTGAQGSHYGWYGVLAGASIVFFAFIGFDIVATMAEE
MUL_2597|M.ulcerans_Agy99 EG-RGADQSLLSLLTGAPGSHYGWYGVLAGASIVFFAFIGFDIVATMAEE
MAV_4216|M.avium_104 QA-KGIDQSVLSLLTGAHTSHYGWYGVLAGASIVFFAFIGFDIVATMAEE
TH_0471|M.thermoresistible__bu EAGRSLDQSLFSLITGAEGSSYGWYGLLAGASIVFFAFIGFDIIATTAEE
MAB_3599c|M.abscessus_ATCC_199 SSRQGLDQSLFSFVAGGSGSQYGWFGVLAGASIVFFAFIGFDVVATTAEE
Mflv_3442|M.gilvum_PYR-GCK SP----------LLP------FGLLGIWAAIPFAIWFFLAIEGVPLAAEE
Mvan_3196|M.vanbaalenii_PYR-1 SA----------LLP------FGLLGIWAAIPFAIWFFLAIEGVPLAAEE
MMAR_0869|M.marinum_M GG---------------------FTAITAGAAVAAYSFLGFDAVSTLTEE
MSMEG_2680|M.smegmatis_MC2_155 NS-----------------ELVTAPLLAAALSIAVLSFLGFDGISTLAEE
MLBr_01974|M.leprae_Br4923 PT-------TYSLLGVTEIGKSTAASMTLATIVALYAFTGFESIANAAEE
: . .. * .:: :. :**
Mb3281c|M.bovis_AF2122/97 TKRPQRDVPRGILASLGVVTLLYVAVSVVLSGMVPYTQLRTVPGRGPANL
Rv3253c|M.tuberculosis_H37Rv TKRPQRDVPRGILASLGVVTLLYVAVSVVLSGMVPYTQLRTVPGRGPANL
MUL_2597|M.ulcerans_Agy99 TKHPQRDVPRGILVSLGVVTLLYVAVSIVLSGMVSYTQLRTVSGGGHANL
MAV_4216|M.avium_104 TKHPQRDVPRGILASLGIVTLLYVAVAVVLSGMVSYTQLKTMPGRGQANL
TH_0471|M.thermoresistible__bu TKNPQRDVARGIMATLGIVTVLYVAVSLVLTGMVHYTELRAAG--ENANL
MAB_3599c|M.abscessus_ATCC_199 TRNPQKDVPRGIIASLVIVTVLYVAVTVVLSGMVKYSDLRVAD--SHPNL
Mflv_3442|M.gilvum_PYR-GCK AEEPERNMPKGIIAGMAVLLVTCVTVLVLTTGAGGAAAMSESG----NPL
Mvan_3196|M.vanbaalenii_PYR-1 TAEPERNVPKGIIAGMAVLLVTCVTVLVLTTGAGGAAAMSESG----NPL
MMAR_0869|M.marinum_M THDAERTIPRAIVLIALIGGAIFVTVAYVVSLVAPGSSFPDADS-LSEGV
MSMEG_2680|M.smegmatis_MC2_155 STGKKNPAGRAMIVSLFIVAFLFITQTWLASLLAGGREAFSDDEAGNAFF
MLBr_01974|M.leprae_Br4923 MNTPDRTLPKAIPLTILTVGVIYILALVVAMLLGSDKIVATNHT---VKL
.. :.: : : .
Mb3281c|M.bovis_AF2122/97 ATAFQANGVYWASGIISVGALAGLTTVVMVLMLGQCRVLFAMARDGLVP-
Rv3253c|M.tuberculosis_H37Rv ATAFQANGVYWASGIISVGALAGLTTVVMVLMLGQCRVLFAMARDGLVP-
MUL_2597|M.ulcerans_Agy99 ATAFKANGVYWASGIISVGALAGLTTVVMVLMLGQCRVLFAMARDGLLP-
MAV_4216|M.avium_104 ATAFTANGIHWASKIISIGALAGLTTVVMVLMLGQCRVLFAMARDGLLP-
TH_0471|M.thermoresistible__bu ATAFAANGIDWAAKVISIGALAGLTTVVIVLVLGQTRVLFAMSRDGLLP-
MAB_3599c|M.abscessus_ATCC_199 STAFHLNGVDWAAKVIAVGALAGLTTVVMVLMLGQIRVIFAMCRDGLLP-
Mflv_3442|M.gilvum_PYR-GCK VEALGDS--TWATVVNYIG-LAGLIASFFSIIYAYSRQLFALSRAGYLP-
Mvan_3196|M.vanbaalenii_PYR-1 VEALGDS--GWAKVVNYIG-LAGLIASFFSIIYAYSRQLFALSRAGYLP-
MMAR_0869|M.marinum_M ARTIGGN---LFAAVFLAALIIGQFTSGLAAQAAVSRLLYAMGRDGVLPR
MSMEG_2680|M.smegmatis_MC2_155 TLVQAASSTGWMNAFFVVNVLAVGFANAMAAQAATSRLLFSMSRDRQLP-
MLBr_01974|M.leprae_Br4923 AAAVGNN---TFRTIIVVGALVSMFGINVAASFGAPRLWTALSDGRILP-
. . . : . . * :: :*
Mb3281c|M.bovis_AF2122/97 RQLAKTGSRGTPVRVTVLVAVLVATTASVFP--ITKLEEMVNVGTLFAFI
Rv3253c|M.tuberculosis_H37Rv RQLAKTGSRGTPVRVTVLVAVLVATTASVFP--ITKLEEMVNVGTLFAFI
MUL_2597|M.ulcerans_Agy99 RQLAKTGARGTPVRITVLVAVVVGATASVFP--ITKLEEMVNVGTLFAFV
MAV_4216|M.avium_104 RALAKTGSRGTPVRITVLVALVVAVTASVFP--ITKLEEMVNVGTLFAFV
TH_0471|M.thermoresistible__bu RPLSKTGPRGTPVRITVLVGALVAIAASVFP--VGNLEEMVNIGTLFAFA
MAB_3599c|M.abscessus_ATCC_199 RELARTGSHGTPIRITLIVGFLVAVAASLTP--IEGLEEIVNVGTLFAFV
Mflv_3442|M.gilvum_PYR-GCK KILSVTNRRKAPTLALLVPGVIGFCLSLIGQ--GALLLNMAVFGAAVSYV
Mvan_3196|M.vanbaalenii_PYR-1 TVLSVTNSRKAPTLALIVPGVIGFLLSLIGQ--GALLLNMAVFGAALSYV
MMAR_0869|M.marinum_M RVFGVVSAKFHTPMFNIMLTGAVGMAAILLS--VATSTSFINFGAFTAFT
MSMEG_2680|M.smegmatis_MC2_155 AFLSKISSRKVPVAALLVVSALSLVLVLFFVGQIGLISSLVNFGALFGFC
MLBr_01974|M.leprae_Br4923 TRLSSKNRFGVPIVAFGITAFLTLAFPLSLRFDSLNLTGLAVIARFIQFI
:. . . : : .. :
Mb3281c|M.bovis_AF2122/97 LVSAGVVVLRRTRPDLQRGFTAP---WVPLLPIAAVCACLWLMLNLTALT
Rv3253c|M.tuberculosis_H37Rv LVSAGVVVLRRTRPDLQRGFTAP---WVPLLPIAAVCACLWLMLNLTALT
MUL_2597|M.ulcerans_Agy99 LVSAGVIVLRKKRPDLERGFRAP---WVPVLPIASLCACLWLMLNLTALT
MAV_4216|M.avium_104 LVSAGVMVLRRTRPDLERGFKAP---WVPVLPIASIGACVWLMLNLTALT
TH_0471|M.thermoresistible__bu LVSAGVIVLRRTRPDLKRGFRVP---FVPWLPLAAIAACLWLMLNLTGLT
MAB_3599c|M.abscessus_ATCC_199 LVSAGVIVLRRSRPDLPRSFRTP---GVPWLPIVAIVACGWLMLNLAVRT
Mflv_3442|M.gilvum_PYR-GCK LMMVSHIVLRRRAPEMHRPYRTPGGVFTTGFALVIAVLAVIATFLVDYVA
Mvan_3196|M.vanbaalenii_PYR-1 LMMVSHIVLRRREPDMPRPYRTPGGVVTTGFALVIAVLAVIATFLVDSVA
MMAR_0869|M.marinum_M LVNVSVVVYFVR----ERGAGLPR-WRYLVLPVIGAAVDIYLLAHLASDA
MSMEG_2680|M.smegmatis_MC2_155 LLHASVIWFYLVRNKSTNYLLHG------VVPTIGFLIIGYVLINADSLA
MLBr_01974|M.leprae_Br4923 IVPIALFALARSRTTNSVYVKRN-VFTDKVLPITAVVVSAGLMVSFDYRS
:: . . .. :
Mb3281c|M.bovis_AF2122/97 WIRFGIWLVAGTAIYVGYGRRHSAQGLRQARESATRRC----------
Rv3253c|M.tuberculosis_H37Rv WIRFGIWLVAGTAIYVGYGRRHSAQGLRQARESATRRC----------
MUL_2597|M.ulcerans_Agy99 WIRFGVWLLVGTVIYVGYGRKHSMVGRRQLAEAAMDK-----------
MAV_4216|M.avium_104 WVRFGIWLVVGTAIYAGYGYWHSVQGRRDAGEPDRSDALAADPNSPVP
TH_0471|M.thermoresistible__bu WVRFLGWMALGLVLYFFYGRHHSMLGRGMTDISARRTG----------
MAB_3599c|M.abscessus_ATCC_199 WLFALSWMVIGVIVYFAYSRKHSVLGLRVDVEQ---------------
Mflv_3442|M.gilvum_PYR-GCK ALGCLLVFAAFMAYFGLYSRHHLVANSPDEEFAALASAEDELR-----
Mvan_3196|M.vanbaalenii_PYR-1 ALCCLVVFAAFMAYFGIYSRHHLVANSPDEEFAALAAAEGELK-----
MMAR_0869|M.marinum_M LIVGLSWAAIGFLYLLWLTRGLTRQPPDLAGAAERG------------
MSMEG_2680|M.smegmatis_MC2_155 KIGGISWLVIGAIVFGVNNVRGRGVPTLTEAA----------------
MLBr_01974|M.leprae_Br4923 IFLTRGGPNYFSISLIAITFIGIPAVAYLHYYRTSGIK----------
.