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MSGEAHSTHTTRGVEAHRESDAYLQKRQLKKGSAGWILLAGLGISYVVSGDYSGWNFGLGQGGFGGLAIA AVVIAAMYLAMVLGMAEMSSALPAAGGGYTFARRALGPWGGFATGTAILIEYSIAPAAIATFIGAYVESL GLFGITDGWWVYLAAYAIFIGIHLSGVGEALKVMFVITAIALVGLVVFAVAAIPHFDSTNLTDIAVTDAA GASALLPFGLLGIWAAIPFAIWFFLAIEGVPLAAEETAEPERNVPKGIIAGMAVLLVTCVTVLVLTTGAG GAAAMSESGNPLVEALGDSGWAKVVNYIGLAGLIASFFSIIYAYSRQLFALSRAGYLPTVLSVTNSRKAP TLALIVPGVIGFLLSLIGQGALLLNMAVFGAALSYVLMMVSHIVLRRREPDMPRPYRTPGGVVTTGFALV IAVLAVIATFLVDSVAALCCLVVFAAFMAYFGIYSRHHLVANSPDEEFAALAAAEGELK
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. vanbaalenii PYR-1 | Mvan_3196 | - | - | 100% (479) | ethanolamine transproter |
| M. vanbaalenii PYR-1 | Mvan_1740 | - | 4e-31 | 25.16% (457) | amino acid permease-associated region |
| M. vanbaalenii PYR-1 | Mvan_0043 | - | 2e-22 | 26.10% (410) | amino acid permease-associated region |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb2347c | rocE | 2e-30 | 26.87% (428) | cationic amino acid transport integral membrane protein RocE |
| M. gilvum PYR-GCK | Mflv_3442 | - | 0.0 | 91.67% (468) | ethanolamine transproter |
| M. tuberculosis H37Rv | Rv2320c | rocE | 2e-30 | 26.87% (428) | cationic amino acid transport integral membrane protein RocE |
| M. leprae Br4923 | MLBr_01305 | ansP2 | 5e-15 | 20.18% (436) | putative L-asparagine permease |
| M. abscessus ATCC 19977 | MAB_2791c | - | 0.0 | 83.69% (466) | putative ethanolamine permease |
| M. marinum M | MMAR_0665 | - | 0.0 | 78.37% (467) | ethanolamine transporter |
| M. avium 104 | MAV_2087 | - | 7e-31 | 26.35% (425) | amino acid transporter |
| M. smegmatis MC2 155 | MSMEG_1552 | eat | 0.0 | 83.55% (468) | ethanolamine permease |
| M. thermoresistible (build 8) | TH_0471 | - | 7e-29 | 26.54% (471) | POSSIBLE CATIONIC AMINO ACID TRANSPORT INTEGRAL MEMBRANE |
| M. ulcerans Agy99 | MUL_1244 | rocE | 1e-32 | 27.85% (438) | cationic amino acid transport integral membrane protein RocE |
CLUSTAL 2.0.9 multiple sequence alignment
Mb2347c|M.bovis_AF2122/97 --MPTTSMSLRELMLRRRPVSGAPVASGASGNLKRSFGTFQLTMFGVGAT
Rv2320c|M.tuberculosis_H37Rv --MPTTSMSLRELMLRRRPVSGAPVASGASGNLKRSFGTFQLTMFGVGAT
MUL_1244|M.ulcerans_Agy99 --MPATSIRLREQMLRRRPAGGAPVAEGAAGSLKRSFGTFELTMFGVGST
MAV_2087|M.avium_104 ------------------------MAPGTADHLRRGIGTFQLTMFGVGST
TH_0471|M.thermoresistible__bu ---------MTDRLRVKSVEQSIADTDEPDSRLRKDLSWWDLTVFGVSVV
Mvan_3196|M.vanbaalenii_PYR-1 ----MSGEAHSTHTTRGVEAHRESDAYLQKRQLKKGSAGWILLAGLGISY
Mflv_3442|M.gilvum_PYR-GCK --------------MRGVEEHRESESYLQKRQLKSGSAGWILLAGLGVSY
MAB_2791c|M.abscessus_ATCC_199 ---------MATTKHGLIEEHLESADYLRKRQLRSGSAGWLLLAGLGVSY
MSMEG_1552|M.smegmatis_MC2_155 ---------MAG-----VEEHLESADYLQKRQLKSGSAGWVLLAGLGVSY
MMAR_0665|M.marinum_M MAGDHEVAHLAGGHLAGTDSHLESPTYLQKRQLRTGSAGWLLLAGLGVSY
MLBr_01305|M.leprae_Br4923 -------MATLAESPEPKSGASRAGVLGEEAGYHKGLKPRQLQMIGIGGA
: . *
Mb2347c|M.bovis_AF2122/97 IGTGIFFVLAQAVP-EAGPGVIVSFIIAGIAAGLAAICYAELASAVPISG
Rv2320c|M.tuberculosis_H37Rv IGTGIFFVLAQAVP-EAGPGVIVSFIIAGIAAGLAAICYAELASAVPISG
MUL_1244|M.ulcerans_Agy99 VGTGIFFVLAEAVP-EAGPAVIVSFIIAGVAAGLAAICCAELASAVPVSG
MAV_2087|M.avium_104 IGTGIFFVMSQAVP-EAGPAVIVSFLLAGVAAGLAAVCYAELASAVPVSG
TH_0471|M.thermoresistible__bu IGAGIFTVTASTAGNITGPAISVSFIIAAIACGLAALCYAEFASTVPVAG
Mvan_3196|M.vanbaalenii_PYR-1 VVSGDYSGWNFGLGQGGFGGLAIAAVVIAAMYLAMVLGMAEMSSALPAAG
Mflv_3442|M.gilvum_PYR-GCK VISGDYSGWNFGLGQGGFGGLAIAAVIIAAMYLAMVLGMAEMSSALPAAG
MAB_2791c|M.abscessus_ATCC_199 VVSGDYSGWNFGLRQGGFGGLALATVVIAGMYLALVLGMAELSSALPTAG
MSMEG_1552|M.smegmatis_MC2_155 VISGDYSGWNFGLEQGGFGGLAIAAIIIAGMYLALVLGMAELSSALPAAG
MMAR_0665|M.marinum_M VISGDYSGWNFGLARGGFGGLAIAAVVIAAMYLALVLSMAELSSALPAAG
MLBr_01305|M.leprae_Br4923 IGTGLFLGAGGRLA-KAGPGLFLVYAVCGVFVFLILRALGELVLHRPSSG
: :* : .: : : . .*: * :*
Mb2347c|M.bovis_AF2122/97 SAYSYAYTTLGEAVAMVVAACLLLEYGVATAAVAVGWSGYVNKLLSNLFG
Rv2320c|M.tuberculosis_H37Rv SAYSYAYTTLGEAVAMVVAACLLLEYGVATAAVAVGWSGYVNKLLSNLFG
MUL_1244|M.ulcerans_Agy99 SSYSYAYATLGEAVAMGVASCLLLEYGVATAAVAVGLSGYVNKLLHNVFG
MAV_2087|M.avium_104 SSYSYAYTTLGEVVAMGVAACLLLEYGVATAAVSVNWSGYLNKLLSNVVG
TH_0471|M.thermoresistible__bu SAYTFSYATFGEFVAWIIGWDLILEFSVAAAVVAKGWSSYLG----EVFE
Mvan_3196|M.vanbaalenii_PYR-1 GGYTFARRALGPWGGFATGTAILIEYSIAPAAIATFIGAYVESLG--LFG
Mflv_3442|M.gilvum_PYR-GCK GGYTFARRALGPWGGFATGTAILIEYAIAPAAIATFIGAYVESLN--LFG
MAB_2791c|M.abscessus_ATCC_199 GGYTFARRALGPWGGFATGTAILIEYSIAPAAIATFIGAYVQSLG--LFG
MSMEG_1552|M.smegmatis_MC2_155 GGYTFARRALGPWGGFATGTAILIEYAIAPAAIATFIGAYVESLG--LFG
MMAR_0665|M.marinum_M GGYTFARRALGPWGGFATGTAVLIEYSIAPAAIATFIGAYVQSLG--LFG
MLBr_01305|M.leprae_Br4923 SFVSYAREFFGEKAAYVVGWLYFLDWAMTAIVDTTAIATYLHRWT--IFT
. ::: :* . . ::::.::. . : . *: :.
Mb2347c|M.bovis_AF2122/97 FQMPHVLSAAPWDTHPG----WVNLPAVILIGLCALLLIRGASESARVNA
Rv2320c|M.tuberculosis_H37Rv FQMPHVLSAAPWDTHPG----WVNLPAVILIGLCALLLIRGASESARVNA
MUL_1244|M.ulcerans_Agy99 FQLPQALSEAPWDERPGEAAGYLNLPAIILIGLCALLLIRGVSESAKVNA
MAV_2087|M.avium_104 FQLPHALSAAPWDAQPG----YVNLPAVMLIGMCALLLIRGASESAKVNA
TH_0471|M.thermoresistible__bu FAG-ATTRLGPITLDWG---------ALLIIGFVTVLLATGTKLSANVSL
Mvan_3196|M.vanbaalenii_PYR-1 ITDGWWVYLAAYAIFIG-------------------IHLSGVGEALKVMF
Mflv_3442|M.gilvum_PYR-GCK ITDGWWVYLAAYALFIG-------------------IHLAGVGEALKVMF
MAB_2791c|M.abscessus_ATCC_199 ITNGWWVYLAAYAFFIG-------------------IHLSGVGEALKVMF
MSMEG_1552|M.smegmatis_MC2_155 ITAGWWIYLAAFAIFIG-------------------IHLAGVGEALKVMF
MMAR_0665|M.marinum_M IRNGWWVYLTIYALFIG-------------------IHLSGVGEALKVMF
MLBr_01305|M.leprae_Br4923 ALPQWTLALLALAVVLV-------------------MNLISVEWFGELEF
: .. .:
Mb2347c|M.bovis_AF2122/97 IMVLIKLGVLGMFMIIAFSAYSADHLKDFVP-------------------
Rv2320c|M.tuberculosis_H37Rv IMVLIKLGVLGMFMIIAFSAYSADHLKDFVP-------------------
MUL_1244|M.ulcerans_Agy99 IMVLIKLGVLGMFVILALTAYDTNHLKDFAP-------------------
MAV_2087|M.avium_104 IMVMVKLGVLVVFGILAFTAFDMHHLDDFAP-------------------
TH_0471|M.thermoresistible__bu AITVIKVGVVLLVVIVGAFFIKAANYTPFIPPAEAGGEAGRSLDQSLFSL
Mvan_3196|M.vanbaalenii_PYR-1 VITAIALVGLVVFAVAAIPHFDSTNLTDIAVTD----------------A
Mflv_3442|M.gilvum_PYR-GCK VITVIALIGIVVFAVAAIPQFDSANLTDIAVTD----------------A
MAB_2791c|M.abscessus_ATCC_199 VITAIALVGLLIFAIAAAGHFDLHNLTNIAADES---------------A
MSMEG_1552|M.smegmatis_MC2_155 VITAIAMVGLVIFALAAIGQFDASNLTNIAPDAG---------------A
MMAR_0665|M.marinum_M IITGVALVGLVVFAIAAVGHFRLANLVDITPSD----------------A
MLBr_01305|M.leprae_Br4923 WAALIKVCALMAFLVVGTIFLGGRYPVDGHNTGLS-------------LW
. : : : . : .
Mb2347c|M.bovis_AF2122/97 --------FGVAGIGSAAGTIFFSYIGLDAVSTAGDEVKDPQKTMPRALI
Rv2320c|M.tuberculosis_H37Rv --------FGVAGIGSAAGTIFFSYIGLDAVSTAGDEVKDPQKTMPRALI
MUL_1244|M.ulcerans_Agy99 --------FGVAGVGAAAGTIFFSFIGLDAVSTAGEEVRNPQQSVPRALI
MAV_2087|M.avium_104 --------FGVAGVGTAAGTIFFSYIGLDAVSTAGDEVTNPQKTMPRALI
TH_0471|M.thermoresistible__bu ITGAEGSSYGWYGLLAGASIVFFAFIGFDIIATTAEETKNPQRDVARGIM
Mvan_3196|M.vanbaalenii_PYR-1 AGASALLPFGLLGIWAAIPFAIWFFLAIEGVPLAAEETAEPERNVPKGII
Mflv_3442|M.gilvum_PYR-GCK AGASPLLPFGLLGIWAAIPFAIWFFLAIEGVPLAAEEAEEPERNMPKGII
MAB_2791c|M.abscessus_ATCC_199 AGSSSILPHGYLGIWAAIPFAIWFFLAVEGVPLAAEETAHPERNVPRGII
MSMEG_1552|M.smegmatis_MC2_155 AGASSFLPHGYLGIWAAIPFAIWFFLAIEGVPLAAEETVNPERNVPRGII
MMAR_0665|M.marinum_M VGASAFLPHGYLGVWSALPFAIWFFLAVEGVPLAAEETADPARNVPRGIT
MLBr_01305|M.leprae_Br4923 TSHGGLFPTGVAPLIVVSSGVMFAYAAVELVGTAAGETVEPKKIMPRAIN
* : :: : ..: : :. *. .* : :.:.:
Mb2347c|M.bovis_AF2122/97 AALVVVTGVYVLVALAALGTQPWQDFAEQ-ETAGLAIILDNVTHGEWAST
Rv2320c|M.tuberculosis_H37Rv AALVVVTGVYVLVALAALGTQPWQDFAEQ-ETAGLAIILDNVTHGEWAST
MUL_1244|M.ulcerans_Agy99 AALFVVTGVYVLVAFAALGTQPWQMFAGQ-EEAGLATILDNVTHSAWAST
MAV_2087|M.avium_104 AALLTVTGVYVFVALAALGTQPWQDFGGQ-QEAGLATILDHVTHGSWAST
TH_0471|M.thermoresistible__bu ATLGIVTVLYVAVSLVLTGMVHYTELRAAGENANLATAFA-ANGIDWAAK
Mvan_3196|M.vanbaalenii_PYR-1 AGMAVLLVTCVTVLVLTTGAGGAAAMSES------GNPLVEALGDSGWAK
Mflv_3442|M.gilvum_PYR-GCK AGMAVLLVTCVTVLVLTTGAGGAAAMSES------GNPLVEALGDSTWAT
MAB_2791c|M.abscessus_ATCC_199 AAIAVLLVTCATALVLTTGAGGAEQMSDS------GNPLVEALGHGTAAK
MSMEG_1552|M.smegmatis_MC2_155 AGMGVLLVTCVVVLFLVTGAGGAEQMSTS------GNPLVEALGDGTAAK
MMAR_0665|M.marinum_M AAFSVLVLTCAAVLLLATGAGGAAAMSSS------GNPLVAALGPTVAAT
MLBr_01305|M.leprae_Br4923 SVIARIAIFYVGSVILLALLLPYSAFKAS---ESPFVTFFSKVGFYGAGD
: : : . . : : .
Mb2347c|M.bovis_AF2122/97 ILAAGAVVSIFTVTLVTMYGQTRILFAMGRDGLLPARFAKVNPRTMTPVH
Rv2320c|M.tuberculosis_H37Rv ILAAGAVVSIFTVTLVTMYGQTRILFAMGRDGLLPARFAKVNPRTMTPVH
MUL_1244|M.ulcerans_Agy99 VLAMGAVISIFTVTLVTMYGQTRILFAMGRDGLLPARFAAVHPRFQTPVS
MAV_2087|M.avium_104 ILAAGAVISIFSVTLVTMYGITRILFAMGRDGLLPPRFARVNPRTMTPVN
TH_0471|M.thermoresistible__bu VISIGALAGLTTVVIVLVLGQTRVLFAMSRDGLLPRPLSKTGPR-GTPVR
Mvan_3196|M.vanbaalenii_PYR-1 VVNYIGLAGLIASFFSIIYAYSRQLFALSRAGYLPTVLSVTNSR-KAPTL
Mflv_3442|M.gilvum_PYR-GCK VVNYIGLAGLIASFFSIIYAYSRQLFALSRAGYLPKILSVTNRR-KAPTL
MAB_2791c|M.abscessus_ATCC_199 LVNYIGLAGLIASFFSIIYAYSRQLFALSRAGYLPTVLSVTNSR-KAPTL
MSMEG_1552|M.smegmatis_MC2_155 VVNYIGLAGLIASFFSIIYAYSRQLFALSRAGYLPRALSVTNKR-KAPTL
MMAR_0665|M.marinum_M VVNYIGLAGLVASFFSIIYAYSRQLFALSRAGYLPTALSITNSR-KAPTL
MLBr_01305|M.leprae_Br4923 LMNIVVLTAALSSLNAGLYATGRVMHSIAINGSGPKFTARMSKN-GVPYG
:: : . : : . * :.::. * * : . .*
Mb2347c|M.bovis_AF2122/97 NTVIVAIFASTLAAFIPLD------SLADMVSIGTLTAFSVVAVGVIVLR
Rv2320c|M.tuberculosis_H37Rv NTVIVAIFASTLAAFIPLD------SLADMVSIGTLTAFSVVAVGVIVLR
MUL_1244|M.ulcerans_Agy99 NTVVVAIAAAVLAALVPLN------RLADMVSIGTLTAFIVVSVGVIILR
MAV_2087|M.avium_104 NTVIVAVAAATLAAFIPLQ------NLADMVSIGTLTAFVVVSVGVIVLR
TH_0471|M.thermoresistible__bu ITVLVGALVAIAASVFPVG------NLEEMVNIGTLFAFALVSAGVIVLR
Mvan_3196|M.vanbaalenii_PYR-1 ALIVPGVIGFLLSLIGQGA------LLLNMAVFGAALSYVLMMVSHIVLR
Mflv_3442|M.gilvum_PYR-GCK ALLVPGVIGFCLSLIGQGA------LLLNMAVFGAAVSYVLMMVSHIVLR
MAB_2791c|M.abscessus_ATCC_199 ALIVPGVVGFALSLTGHGD------LLLNMAVFGAALSYVLMMVSHITLR
MSMEG_1552|M.smegmatis_MC2_155 ALVIPGIIGFLLSLTGQGD------LLLNMAVFGAALSYVLMMVSHITLR
MMAR_0665|M.marinum_M ALIVPGVIGFALSVTGEGD------LLLNMAVFGATLSYVLMMISHIVLR
MLBr_01305|M.leprae_Br4923 GILLAAVICLCGVALNAFNPGQAFEIVLSVAALGIIAGWGTIVLCQLRLH
:: . : .:. :* .: : : *:
Mb2347c|M.bovis_AF2122/97 VREPD--LPRG-FKVPGYPVTPVLSVLACGYILAS---LHWYTWLAFSGW
Rv2320c|M.tuberculosis_H37Rv VREPD--LPRG-FKVPGYPVTPVLSVLACGYILAS---LHWYTWLAFSGW
MUL_1244|M.ulcerans_Agy99 VREPA--LPRG-FWVPGYPVTPILSILACGYLLYS---LHWYTWIAFGGW
MAV_2087|M.avium_104 VREPD--LPRG-FRVPGYPVTPVLSIMACGYILAS---LHWYTWIAFSGW
TH_0471|M.thermoresistible__bu RTRPD--LKRG-FRVPFVPWLPLAAIAACLWLMLN---LTGLTWVRFLGW
Mvan_3196|M.vanbaalenii_PYR-1 RREPD--MPRP-YRTPGGVVTTGFALVIAVLAVIATFLVDSVAALCCLVV
Mflv_3442|M.gilvum_PYR-GCK RRAPE--MHRP-YRTPGGVFTTGFALVIAVLAVIATFLVDYVAALGCLLV
MAB_2791c|M.abscessus_ATCC_199 VREPN--MPRP-YRTPGGIVTTSFALIVAVLAVAATFLVNPVAAGLCLAV
MSMEG_1552|M.smegmatis_MC2_155 VREPN--MPRP-YRTPGGAVTTGFALVVACFAVIATFLVNPIAAGLCLLV
MMAR_0665|M.marinum_M RRAAD--MARP-YRTPGGIATSGFALLVAATALIATFLVDTVAALCCLGV
MLBr_01305|M.leprae_Br4923 KMAKAGIMRRPRFRMPLAPYSGYLTLAFLFAVLVVMAFDKPIGTWTVASL
: * : * :: :
Mb2347c|M.bovis_AF2122/97 VAVAVIFYLMWG----------RHHSALNEEVP-----------------
Rv2320c|M.tuberculosis_H37Rv VAVAVIFYLMWG----------RHHSALNEEVP-----------------
MUL_1244|M.ulcerans_Agy99 VGIALIFYLFWG----------RHHSRLNAPALHDNPTGEER--------
MAV_2087|M.avium_104 VLLALIFYFVWG----------RHHSALNDAAVD--PSGQER--------
TH_0471|M.thermoresistible__bu MALGLVLYFFYG----------RHHSMLGRGMTDISARRTG---------
Mvan_3196|M.vanbaalenii_PYR-1 FAAFMAYFGIYS----------RHHLVANSPDEEFAALAAAEGELK----
Mflv_3442|M.gilvum_PYR-GCK FAAFMAYFGLYS----------RHHLVANSPDEEFAALASAEDELR----
MAB_2791c|M.abscessus_ATCC_199 FAAFMAYFALYS----------RHRLVANSPDEEFAILAEAESELT----
MSMEG_1552|M.smegmatis_MC2_155 FAGFMLYFAVYS----------RHRLVANSPDEEFAMLAEAENELK----
MMAR_0665|M.marinum_M FCAFILYFALYS----------RHQLVANSPDEELAGSQDFESELQ----
MLBr_01305|M.leprae_Br4923 IVIVPALIAGWYSIRKRVMTIARERMGYTGPFPAIANPPVQPSERSHSQN
. : *.:
Mb2347c|M.bovis_AF2122/97 -
Rv2320c|M.tuberculosis_H37Rv -
MUL_1244|M.ulcerans_Agy99 -
MAV_2087|M.avium_104 -
TH_0471|M.thermoresistible__bu -
Mvan_3196|M.vanbaalenii_PYR-1 -
Mflv_3442|M.gilvum_PYR-GCK -
MAB_2791c|M.abscessus_ATCC_199 -
MSMEG_1552|M.smegmatis_MC2_155 -
MMAR_0665|M.marinum_M -
MLBr_01305|M.leprae_Br4923 P