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MTALHTFPPERTAVVTGAGSARGIGRATVQRLARAGWHVAALDVDEAAVVEFAREVDKDSRTTVFGYGVD VVDAESVDRAFTAIEAELPPVVGLAHAAGVASPVPFLELTLAEWNRVLDINSTGTFIVNQRAVRGMVQRG VGRVVNLSSASAQLGGGTYSKVPYSASKASVIGLSRAVAREVGKFGVTVNVVSPGPIDTDIMGGTLTEER KAEMVEGLLVDRVGRTEDIAATIEFLLSEDAGFITAAVYNVNGGLVVN
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. smegmatis MC2 155 | MSMEG_2548 | - | - | 100% (258) | 3-oxoacyl- |
| M. smegmatis MC2 155 | MSMEG_6538 | - | 5e-39 | 40.16% (254) | 3-oxoacyl-(acyl-carrier-protein) reductase, putative |
| M. smegmatis MC2 155 | MSMEG_0294 | fabG | 5e-37 | 38.74% (253) | 3-oxoacyl-(acyl-carrier-protein) reductase |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb1519 | fabG1 | 3e-37 | 38.71% (248) | 3-oxoacyl- |
| M. gilvum PYR-GCK | Mflv_2501 | - | 6e-40 | 40.16% (249) | short-chain dehydrogenase/reductase SDR |
| M. tuberculosis H37Rv | Rv1483 | fabG1 | 3e-37 | 38.71% (248) | 3-oxoacyl- |
| M. leprae Br4923 | MLBr_01807 | fabG1 | 2e-33 | 35.10% (245) | 3-oxoacyl- |
| M. abscessus ATCC 19977 | MAB_2723c | - | 3e-32 | 33.47% (245) | 3-oxoacyl- |
| M. marinum M | MMAR_4715 | - | 6e-37 | 38.87% (247) | 3-oxoacyl- |
| M. avium 104 | MAV_1395 | - | 7e-41 | 41.60% (250) | 2-hydroxycyclohexanecarboxyl-CoA dehydrogenase |
| M. thermoresistible (build 8) | TH_3102 | - | 7e-39 | 38.06% (247) | PUTATIVE short-chain dehydrogenase/reductase SDR |
| M. ulcerans Agy99 | MUL_1491 | fabG1 | 2e-36 | 38.78% (245) | 3-oxoacyl- |
| M. vanbaalenii PYR-1 | Mvan_4157 | - | 7e-40 | 40.56% (249) | short-chain dehydrogenase/reductase SDR |
CLUSTAL 2.0.9 multiple sequence alignment
Mflv_2501|M.gilvum_PYR-GCK ----------------------MKNAVVTGGAS--GIGAAVVERLRADGL
Mvan_4157|M.vanbaalenii_PYR-1 ----------------------MKNAVVTGGAS--GIGAAIAERLRADGM
TH_3102|M.thermoresistible__bu ----------------------LKNAVVTGGGS--GIGQAVAARLRADGY
MMAR_4715|M.marinum_M ----------------------MKTAVVTGGAS--GIGLAIARRLRADGI
MAV_1395|M.avium_104 ------------------------MAVVTGGGS--GIGRAIVERLAHDGH
MSMEG_2548|M.smegmatis_MC2_155 MTALHTFPP-------------ERTAVVTGAGSARGIGRATVQRLARAGW
Mb1519|M.bovis_AF2122/97 MTATATEG--------AKPPFVSRSVLVTGGNR--GIGLAIAQRLAADGH
Rv1483|M.tuberculosis_H37Rv MTATATEG--------AKPPFVSRSVLVTGGNR--GIGLAIAQRLAADGH
MUL_1491|M.ulcerans_Agy99 MTDTATEQNTESAADGGKPAFVSRSVLVTGGNR--GIGLAIAQRLATDGH
MLBr_01807|M.leprae_Br4923 MTDAAAKVS--AAPGRGKPAFVSRSILVTGGNR--GIGLAVARRLVADGH
MAB_2723c|M.abscessus_ATCC_199 MTNA---------------EFVPRSVLVTGGNR--GIGLAVAQRLAADGH
:***. *** * . ** *
Mflv_2501|M.gilvum_PYR-GCK QVATIDLNPGDAK--------------FSYAADVTDRSAVDAALDEIRAE
Mvan_4157|M.vanbaalenii_PYR-1 RVATIDLNPGDEK--------------FSYAADVTDRAAVDAVLSEIHTE
TH_3102|M.thermoresistible__bu HVATIDLKPGDDE--------------FSHAADVTDRAQVDAAFDAIRTQ
MMAR_4715|M.marinum_M DVATLDLKTPDGE--------------LAFSADVTNRSQVDAALTAIRQR
MAV_1395|M.avium_104 RVAVLDVNEEAAEKVAARVAADG-AHAIAVPTDVAESASVAAAFESVRRA
MSMEG_2548|M.smegmatis_MC2_155 HVAALDVDEAAVVEFAREVDKDSRTTVFGYGVDVVDAESVDRAFTAIEAE
Mb1519|M.bovis_AF2122/97 KVAVTHRGSGAPKG------------LFGVECDVTDSDAVDRAFTAVEEH
Rv1483|M.tuberculosis_H37Rv KVAVTHRGSGAPKG------------LFGVECDVTDSDAVDRAFTAVEEH
MUL_1491|M.ulcerans_Agy99 RVAVTHRGSGAPEG------------LFGVECDVTDNDAVDRAFKEVEEH
MLBr_01807|M.leprae_Br4923 RVAVTHRASVVPDW------------FFGVECDVTDNDAIGAAFKAVEEH
MAB_2723c|M.abscessus_ATCC_199 KVAVTHRGSGAPEG------------LLGVQCDITDNDQIDAAFKEVEEK
**. . :. *:.: : .: :.
Mflv_2501|M.gilvum_PYR-GCK LGPVTVLVNAAGLDRFKKFLDLSFEEWQKVVDVNLNGVFHCTQAVLPDMI
Mvan_4157|M.vanbaalenii_PYR-1 LGPVTVLVNAAGLDRFKKFLDLTFDEWQKVVDVNLNGVFHCTQAVLPDMI
TH_3102|M.thermoresistible__bu LGPVTILVNAAGLDLFRRFTDISFEDWERVINVNLHGVFHCIQAVLPDMI
MMAR_4715|M.marinum_M LGPVTILVNAAGLDGFKRFSNITFEDWQRVIDVNLNGVFHTIQAVLPDMV
MAV_1395|M.avium_104 LGSVQVLVTSAAITGFKPFAEITIEDWNRHLAVNLTGTFLCLQAALPDMV
MSMEG_2548|M.smegmatis_MC2_155 LPPVVGLAHAAGVASPVPFLELTLAEWNRVLDINSTGTFIVNQRAVRGMV
Mb1519|M.bovis_AF2122/97 QGPVEVLVSNAGLSADAFLMRMTEEKFEKVINANLTGAFRVAQRASRSMQ
Rv1483|M.tuberculosis_H37Rv QGPVEVLVSNAGLSADAFLMRMTEEKFEKVINANLTGAFRVAQRASRSMQ
MUL_1491|M.ulcerans_Agy99 QGPVEVLVSNAGLSADAFLIRMTEERFEKVIDANLTGAFRVAQRASRSMQ
MLBr_01807|M.leprae_Br4923 QGPVEVLVANAGITSDMLIMRMSEEQFQKVIDVNLTGVFRVAKLASRNMI
MAB_2723c|M.abscessus_ATCC_199 QGPVEVLVANAGITADMLIMRMSEEQFLKVIDANLIGTFRLAKRASRNMI
.* *. *.: : :: : : : * *.* : . .*
Mflv_2501|M.gilvum_PYR-GCK EAGWGRIVNISSSSTHSG--QPYMSPYVAAKSAVNGLTKSLALEYGPAGI
Mvan_4157|M.vanbaalenii_PYR-1 EAGWGRIVNISSSSTHSG--QPYMSPYVAAKSAVNGLTKSLALEYGPDGI
TH_3102|M.thermoresistible__bu EAGWGRIVNISSSSTHSG--APYMAPYVAAKSGVNGLTKTLALEYGPAGI
MMAR_4715|M.marinum_M AAGWGRIVNISSSSTHSG--TPYMTHYVAAKSAVNGLTKALALEYGPSGI
MAV_1395|M.avium_104 EAGWGRVVTISSTAAQTG--SPRQGHYSASKGGVIALTRTIALEYAAHGI
MSMEG_2548|M.smegmatis_MC2_155 QRGVGRVVNLSSASAQLGGGTYSKVPYSASKASVIGLSRAVAREVGKFGV
Mb1519|M.bovis_AF2122/97 RNKFGRMIFIGSVSGSWG--IGNQANYAASKAGVIGMARSIARELSKANV
Rv1483|M.tuberculosis_H37Rv RNKFGRMIFIGSVSGSWG--IGNQANYAASKAGVIGMARSIARELSKANV
MUL_1491|M.ulcerans_Agy99 RKKFGRLIFIGSVSGSWG--IGNQANYAASKAGVIGMARSIARELSKVNV
MLBr_01807|M.leprae_Br4923 KQRFGRYIFMGSVVGLSG--VPGQANYAASKSGLIGMARSLARELGSRSI
MAB_2723c|M.abscessus_ATCC_199 KKRFGRLIFMGSVAGQIG--LPGQANYSASKAGLVGMARALTRELGSRSI
** : :.* * * *:*..: .:::::: * . .:
Mflv_2501|M.gilvum_PYR-GCK TVNAVPPGFIDTPMLRKAEQRGFLGDTEQQIQQTPVRRMGRPEDIAAACA
Mvan_4157|M.vanbaalenii_PYR-1 TVNAVPPGFIDTPMLRKAEQRGFLGDTQKQIEQTPVRRMGRPEDIAAACS
TH_3102|M.thermoresistible__bu TVNAVPPGFIDTPMLRAAAAKGYLGDIDKTIEATPVRRMGKPEDIAAACA
MMAR_4715|M.marinum_M TVNAVPPGFIDTPMLRNAAAQGHLGDIEQNIARTPVRRIGKPEDIAAACA
MAV_1395|M.avium_104 TANTVPPFSVDTPMLRAAQEAGNLPPVKYLAKASPVGRLGTGEDIAAACA
MSMEG_2548|M.smegmatis_MC2_155 TVNVVSPGPIDTDIMGGTLTE---ERKAEMVEGLLVDRVGRTEDIAATIE
Mb1519|M.bovis_AF2122/97 TANVVAPGYIDTDMTRALDER----IQQGALQFIPAKRVGTPAEVAGVVS
Rv1483|M.tuberculosis_H37Rv TANVVAPGYIDTDMTRALDER----IQQGALQFIPAKRVGTPAEVAGVVS
MUL_1491|M.ulcerans_Agy99 TANVVAPGYIDTDMTRALDER----IQEGALQFIPAKRVGTAAEVAGVVS
MLBr_01807|M.leprae_Br4923 TANVVAPGFIDTEMTRAMDSK----YQEAALQAIPLGRIGAVEEIAGAVS
MAB_2723c|M.abscessus_ATCC_199 TANVVAPGFIDTDMTRELGEK----HVETALTAIPMGRIGEPSEVAGVVS
*.*.*.* :** : *:* ::*..
Mflv_2501|M.gilvum_PYR-GCK FFISEEAGYITGQILGVNGGRNT--
Mvan_4157|M.vanbaalenii_PYR-1 FLISEEAGYITGQILGVNGGRNT--
TH_3102|M.thermoresistible__bu FLISEEAGYITGQILGVNGGRNT--
MMAR_4715|M.marinum_M FLVSEEAGYITGQILGVNGGRNT--
MAV_1395|M.avium_104 FLCSDEAGYITGQIIGVNGGEVI--
MSMEG_2548|M.smegmatis_MC2_155 FLLSEDAGFITAAVYNVNGGLVVN-
Mb1519|M.bovis_AF2122/97 FLASEDASYISGAVIPVDGGMGMGH
Rv1483|M.tuberculosis_H37Rv FLASEDASYISGAVIPVDGGMGMGH
MUL_1491|M.ulcerans_Agy99 FLASEDASYISGAVIPVDGGMGMGH
MLBr_01807|M.leprae_Br4923 FLASEDAGYISGAVIPVDGGLGMGH
MAB_2723c|M.abscessus_ATCC_199 WLASPDAAYVSGAVIPVDGGLGMGH
:: * :*.:::. : *:**