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VATILAYTSPALGHVYPLAALLTELACRGHEIHLRTMAREVEAMRAAGFRADAVAPEIEAIRGDDRSTSD ALEVLAMSLDVLCSRAASEVDDIRDAIARSRPDLVIVDANCWGAMAAAEAEGLPWAVFSPFTPYLRSRGV PPFGPGLRPWPGLPGRARDALMRRVTGRMFDDPVLRRMNPLRAEAGVPEVDSVDAMMRRAPLTLGVGGRP FEYPHPDWGDSVHQLGACVFEPGPVAEPPWLAEIDRPVVLVNTSSIAQADTILAHTALAAFADEPVHVVA TFPAGVPDGLPRPANATIGEYIPHGVVLDRTVCVVTHGGMGTTLKALDRGIPVCVVPFARDQAEVARRVQ MARCGTRLPAKHLSAARLRRKVRQAMAMSDGARRVAAGFAATGGVVRGADLIEQQVFSSEMRM
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. smegmatis MC2 155 | MSMEG_2342 | - | - | 100% (413) | putative glycosyltransferase |
| M. smegmatis MC2 155 | MSMEG_4670 | - | 3e-28 | 28.57% (434) | N-glycosylation |
| M. smegmatis MC2 155 | MSMEG_2699 | - | 3e-28 | 31.30% (409) | hypothetical protein MSMEG_2699 |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb2759c | - | 1e-28 | 30.37% (405) | alanine rich transferase |
| M. gilvum PYR-GCK | Mflv_0466 | - | 1e-123 | 54.43% (406) | glycosyl transferase family protein |
| M. tuberculosis H37Rv | Rv2739c | - | 1e-28 | 30.37% (405) | alanine rich transferase |
| M. leprae Br4923 | MLBr_00985 | - | 7e-27 | 30.79% (406) | putative glycosyltransferase |
| M. abscessus ATCC 19977 | MAB_3062c | - | 3e-32 | 31.16% (398) | hypothetical protein MAB_3062c |
| M. marinum M | MMAR_1974 | - | 2e-25 | 29.83% (409) | glycosyl transferase |
| M. avium 104 | MAV_3631 | - | 4e-30 | 33.01% (412) | hypothetical protein MAV_3631 |
| M. thermoresistible (build 8) | TH_4587 | - | 1e-22 | 25.72% (416) | PUTATIVE putative oleandomycin glycosyltransferase |
| M. ulcerans Agy99 | MUL_3383 | - | 3e-25 | 29.00% (400) | glycosyl transferase |
| M. vanbaalenii PYR-1 | Mvan_1905 | - | 1e-117 | 52.46% (406) | glycosyl transferase family protein |
CLUSTAL 2.0.9 multiple sequence alignment
Mflv_0466|M.gilvum_PYR-GCK ---MAVILAYTAPALGHLFPFCAVLQELARRGHDIHVRTLAAGLQICRDE
Mvan_1905|M.vanbaalenii_PYR-1 ---MATILAYTSPALGHLLPMGALLSELSRRGHTVHLRTLSSGLDHARGL
MSMEG_2342|M.smegmatis_MC2_155 ---MATILAYTSPALGHVYPLAALLTELACRGHEIHLRTMAREVEAMRAA
MMAR_1974|M.marinum_M ----MRVAVVAGPDPGHSFPAIALCRRFLAAGDIPTLLTGVEWLDTARAA
MUL_3383|M.ulcerans_Agy99 ----MRVAVVAGPDPGHSFPAIALCRRFLAAGDIPTLLTGVEWLDTARAA
MAV_3631|M.avium_104 ----MRVAVVAGPDPGHSFPAIALCRRFADAGDTPTLFTGAEWLDTARGA
Mb2759c|M.bovis_AF2122/97 ----MRVAVVAGPDPGHSFPAIALCQRFRAAADTPTLFTGVEWLEAARAA
Rv2739c|M.tuberculosis_H37Rv ----MRVAVVAGPDPGHSFPAIALCQRFRAAADTPTLFTGVEWLEAARAA
MLBr_00985|M.leprae_Br4923 MVHYMRVAVVAGPDPGHSFPAIALCQRFAEAGDTPTLFTGVECVDIARAA
MAB_3062c|M.abscessus_ATCC_199 ----MRVAVVAGPDPGHAFPALALCLKFAAAGDDPVLLTGTRWLDQARAA
TH_4587|M.thermoresistible__bu ---VAHIVFAVPVGVGHVNPTLGVAAELIARGHRVSYAATERHAARIADV
: . ** * .: .: .. :
Mflv_0466|M.gilvum_PYR-GCK GFTAAAVDPRIEAIQADDTLTG-TVRAAADTVEVLTARAPLEVADLLSAV
Mvan_1905|M.vanbaalenii_PYR-1 GVSVEPIDPRIEAIELDDWKASNPVGALKLSIGAFGRRASYEIADLGKAL
MSMEG_2342|M.smegmatis_MC2_155 GFRADAVAPEIEAIRGDDRSTSDALEVLAMSLDVLCSRAASEVDDIRDAI
MMAR_1974|M.marinum_M GVDAIELAGLVA--TDEDLDAGARIHRRAAQMALLN----------APAL
MUL_3383|M.ulcerans_Agy99 GVDAIELAGLVA--TDEDLDAGARIHRRAAQMALLN----------APAL
MAV_3631|M.avium_104 GVDAVELDGLAA--TDEDVDAGARIHRRAARMAVLN----------VPAL
Mb2759c|M.bovis_AF2122/97 GIDAVELDGLAA--TDRDLDAGARIHRRAAQMAVLN----------VPRL
Rv2739c|M.tuberculosis_H37Rv GIDAVELDGLAA--TDRDLDAGARIHRRAAQMAVLN----------VPRL
MLBr_00985|M.leprae_Br4923 GVETALLDGLVA--VDDDVDAGARIHRRAAQMAVLN----------VPVL
MAB_3062c|M.abscessus_ATCC_199 GVESVELLGLQPRVDDDDADSGAKIHQRAAHMALAN----------LDQL
TH_4587|M.thermoresistible__bu GARLVPYATTLSGPEPPPQFTARDFHRATEAALRET--------------
* :. .
Mflv_0466|M.gilvum_PYR-GCK ESVQPDVVIVDANCWGAMSVAETLGRPWVVLSPFTPYLRSPGAPPFGPGA
Mvan_1905|M.vanbaalenii_PYR-1 TTVQPDGVLVDVNCWGAHSAVEATGVPWASFAPYTPALTVAGVPPFGLGL
MSMEG_2342|M.smegmatis_MC2_155 ARSRPDLVIVDANCWGAMAAAEAEGLPWAVFSPFTPYLRSRGVPPFGPGL
MMAR_1974|M.marinum_M SDLAPDLVVSDVITACGGMAAERLGIPWIELNPHPLYRPSKGLPPIGSGL
MUL_3383|M.ulcerans_Agy99 SDLAPDLVVSDVITACGGMAAERLGIPWIELNPHPLYRPSKGLPPIGSGL
MAV_3631|M.avium_104 RDLAPDLVVSDVITAGGGMAAELLGIPWIELSPHPLYLPSKGLPPIGSGL
Mb2759c|M.bovis_AF2122/97 RALEPELVVSDVITACGGMAAELLGIPWVELNPHPLYLPSKGLPPIGSGL
Rv2739c|M.tuberculosis_H37Rv RALEPELVVSDVITACGGMAAELLGIPWVELNPHPLYLPSKGLPPIGSGL
MLBr_00985|M.leprae_Br4923 RDLAPDLIVSDVITAAGGMAAELLGIPWIELNPHPLYLPSKGLPPIGSGL
MAB_3062c|M.abscessus_ATCC_199 RALAPDLIVSDVITACGGMAGELLGVPWVELNPHPLYLPSKGLPPLGSGL
TH_4587|M.thermoresistible__bu GHVLPQVLDGFAGDRPDLVLHDATMAWWGRLAAAAWEVPVVAGWPNLVGN
*: : . : * : . . . * *
Mflv_0466|M.gilvum_PYR-GCK TPWPGPLGRIRDWGIGLVTTAVFDRPFARQIAPLRRALGLTPVRTAGDLL
Mvan_1905|M.vanbaalenii_PYR-1 KPMSGPVGRLRDSVVRAGVSWPLERPAVAAINTVRSRVGLTPVGSLDQFL
MSMEG_2342|M.smegmatis_MC2_155 RPWPGLPGRARDALMRRVTGRMFDDPVLRRMNPLRAEAGVPEVDSVDAMM
MMAR_1974|M.marinum_M APGTGIRGRLRDTTMRALTARSWR-AGLRQRAAVRAEIGLAEHD------
MUL_3383|M.ulcerans_Agy99 APGTGIRGRLRDTTMRALTARSWR-AGLRQRAAVRAEIGLAEHD------
MAV_3631|M.avium_104 ATGTGLRGRLRDATMRALTARSWR-AGLRQRAAARAEIGLPARD------
Mb2759c|M.bovis_AF2122/97 AAGTGIRGRLRDATMRALTGRSWR-AGLRQRAAVRVEIGLPARD------
Rv2739c|M.tuberculosis_H37Rv AAGTGIRGRLRDATMRALTGRSWR-AGLRQRAAVRVEIGLPARD------
MLBr_00985|M.leprae_Br4923 ASGVGIHGRMRDATMRALTARSWR-AGLRERAAVRVQIGLPACD------
MAB_3062c|M.abscessus_ATCC_199 APGVGLRGRLRDGLMRRLTQKSID-QGLRQRSQARVEIGLPARD------
TH_4587|M.thermoresistible__bu RHWSMNRYIKVNPLHPRLLWNLWR---AHRLARRHGLTGLSLVR-----A
: : *:.
Mflv_0466|M.gilvum_PYR-GCK LRAPAVLVATGKPLEYPHTDWGETVTMIGPAVFE-PRAAQRPSWLDHIDD
Mvan_1905|M.vanbaalenii_PYR-1 RRAPLLFLATGTPFQY-AADWGENVHMIGPCAPE-KAHGDAPDWLTAIDR
MSMEG_2342|M.smegmatis_MC2_155 RRAPLTLGVGGRPFEYPHPDWGDSVHQLGACVFE-PGPVAEPPWLAEIDR
MMAR_1974|M.marinum_M PGPLRRLIATLPALEVPRPDWPAEAIVVGPLHFE-PTDQLLK--VPAGSG
MUL_3383|M.ulcerans_Agy99 PGPLRRLIATLPALEVPRPDWPAEAIVVGPLHFE-PTDQLLK--VPAGSG
MAV_3631|M.avium_104 PGPLRRLIATLPALEVPRPDWPDEAVLVGPLHFE-PTDRVLD--IPAGSG
Mb2759c|M.bovis_AF2122/97 PGPLRRLIATLPALEVPRPDWPAEAVVVGPLHFE-PTDRVLA--IPAGTG
Rv2739c|M.tuberculosis_H37Rv PGPLRRLIATLPALEVPRPDWPAEAVVVGPLHFE-PTDRVLA--IPAGTG
MLBr_00985|M.leprae_Br4923 SGPLRRLIATLPALEVSRPDWPAEAVVVGPLHFE-PTDRVLQ--IPSGSG
MAB_3062c|M.abscessus_ATCC_199 PGPMRRLIATLPALEVPRPDWPAEAVVVGPLHWE-PTDVVLQ--PPSGSG
TH_4587|M.thermoresistible__bu TAADAQLVYLPREFQYAGDTFGAHYAFVGPCLVDRPSDGEWRPPPGRDGR
. : :: : :*. :
Mflv_0466|M.gilvum_PYR-GCK PIVLVTTSSVGQSDAALVETAVEALRD-----EPVHLVVTAPTGDVD---
Mvan_1905|M.vanbaalenii_PYR-1 PIVLVTTSSERQGDAGLVSAAVDALTD-----EPVHVVATLPAGVDQ---
MSMEG_2342|M.smegmatis_MC2_155 PVVLVNTSSIAQADTILAHTALAAFAD-----EPVHVVATFPAGVPDG--
MMAR_1974|M.marinum_M PVLVIAPSTALSGTAGLAEVALESLIPGDTLPSGSRLVVSRLGGDDL---
MUL_3383|M.ulcerans_Agy99 PVLVIAPSTALSGTAGLAEVALESLIPGGTLSSGSRLVVSRLGGDDL---
MAV_3631|M.avium_104 PVVVVAPSTAQTGARGLAEVALSCLTPGETLPAGARLVVSRLAGPEL---
Mb2759c|M.bovis_AF2122/97 PVVVVAPSTALTGTAGLTEVALQSLTPGETVPSGSRLVVSRLSGADL---
Rv2739c|M.tuberculosis_H37Rv PVVVVAPSTALTGTAGLTEVALQSLTPGETVPSGSRLVVSRLSGADL---
MLBr_00985|M.leprae_Br4923 PVIVVAPSTALTGISGMAQTALDALVPGDTLPSGSRVVVSRLNGPDL---
MAB_3062c|M.abscessus_ATCC_199 PVVVIAPSTAFTGAEGMTELAVQALES-----AGARVVISALEPPSS---
TH_4587|M.thermoresistible__bu RVVLIALGTAYHDRADFFRTCLAAFAD-----SGWHVVLAVGDRVDPAGL
:::: .: : .: .: ::* :
Mflv_0466|M.gilvum_PYR-GCK VMTRPGVTQVRFAPHSMLLEHAVCVITHGGMGVTQKALARGVPVCVVPFG
Mvan_1905|M.vanbaalenii_PYR-1 VPGSAHATILRFVDHDLVLGRAVCAVTHGGMGATQRALARGVPVCVVPYG
MSMEG_2342|M.smegmatis_MC2_155 LPRPANATIGEYIPHGVVLDRTVCVVTHGGMGTTLKALDRGIPVCVVPFA
MMAR_1974|M.marinum_M --VTPSWAAVGLGSQAELLTHADVVICGGGHGMVSKTLLAGVPLVVVPGG
MUL_3383|M.ulcerans_Agy99 --VTPSWAAVGLGSQAELLTHADVVICGGGHGMVSKTLLAGVPLVVVPGG
MAV_3631|M.avium_104 --AAPPWAVVGLGSQAELLRHADVVVCGGGHGMVAKTLLAGVPLVAVPGG
Mb2759c|M.bovis_AF2122/97 --TVPPWAVAGLGSQAELLTRADLVICGGGHGMVAKTLLAGVPMVVVPGG
Rv2739c|M.tuberculosis_H37Rv --TVPPWAVAGLGSQAELLTRADLVICGGGHGMVAKTLLAGVPMVVVPGG
MLBr_00985|M.leprae_Br4923 --TVPSWAVAGLVHQTKLLAHADVVICGGGHGMVAKTLLAGVPLVVVPGG
MAB_3062c|M.abscessus_ATCC_199 --GLPSWAIAGLARQDLLLSGADLAVCGGGHGFLSKALLAGVPTVVVPGG
TH_4587|M.thermoresistible__bu GPVPPHVEVHASVPQLQVLRHASVFVSHAGMGSVMEALAHRVPIVAVPQM
. : :* : : .* * .:* :* .**
Mflv_0466|M.gilvum_PYR-GCK RDQFEVARRVELAGCGTRLPAGKLSVGRLRTAVKTAAT---MTGGAARVA
Mvan_1905|M.vanbaalenii_PYR-1 RDQFEVARRAEVARCGTRLPAKRLSAPRLRNKIREAMG---LTSGARAVA
MSMEG_2342|M.smegmatis_MC2_155 RDQAEVARRVQMARCGTRLPAKHLSAARLRRKVRQAMA---MSDGARRVA
MMAR_1974|M.marinum_M GDQWEIANRVVRQ--GSARLIRPLGAEALAAAVNEVLS---SPGYREAAQ
MUL_3383|M.ulcerans_Agy99 GDQWEIANRVVRQ--GSARLIRPLGADALAAAVNEVLS---SPGYREAAQ
MAV_3631|M.avium_104 GDQWEIANRVVRQ--GSARLIRPLSADALVAAVNEVLS---SPGYRAAAQ
Mb2759c|M.bovis_AF2122/97 GDQWEIANRVVRQ--GSAVLIRPLTADALVAAVNEVLS---SPRFREAAR
Rv2739c|M.tuberculosis_H37Rv GDQWEIANRVVRQ--GSAVLIRPLTADALVAAVNEVLS---SPRFREAAR
MLBr_00985|M.leprae_Br4923 GDQWEMANRVVRQ--GSAQLIRPLTAAALLAAVNKVLS---SPDYREAAQ
MAB_3062c|M.abscessus_ATCC_199 GDQWELANRVVRQ--GSAELVRPLSRDSLASAIGRVLG---EPRYREAAR
TH_4587|M.thermoresistible__bu TEQQANADRIAELNLGVRLGRDEITADRLRSAVERVAGSATIAAAVRTMH
:* * * * : * : . .
Mflv_0466|M.gilvum_PYR-GCK AGFAATGGVARGADVVESRLVARCALPEEQ
Mvan_1905|M.vanbaalenii_PYR-1 DGFAATGGVARGADLFEHLVGGN-------
MSMEG_2342|M.smegmatis_MC2_155 AGFAATGGVVRGADLIEQQVFSSEMRM---
MMAR_1974|M.marinum_M RAAASIADVADPVQVCHEALALAG------
MUL_3383|M.ulcerans_Agy99 RAAASIADVADPVQVCHEALALAG------
MAV_3631|M.avium_104 RAAAGIADVADPVRVCREALAG--------
Mb2759c|M.bovis_AF2122/97 RAAASVAGAADPVRVCHDALALAG------
Rv2739c|M.tuberculosis_H37Rv RAAASVAGAADPVRVCHDALALAG------
MLBr_00985|M.leprae_Br4923 RAAISIAGVADPVQVCHEALGLAG------
MAB_3062c|M.abscessus_ATCC_199 RAAAGAIAVEDPVRVCQDVLAALR------
TH_4587|M.thermoresistible__bu DAITAAGGAAAAADIVEDVLTRSR------
. . . . : . :