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MFALATLMALVQQVSGTPYVSGGDSPSGTDCSGLASWVSNVATGRPAFGDRFHTGNQEQALLARGFKYGT QPGALVIGWNSGHTAVTLPDGTPVSSGEGGGVKIGGGGAYQPQFNHHMYLPAEEVQPDAGLPVGAPPPPE ASLPPLPPPPADPMAPAPPMAGPPPVDPFAPPPPPEPAVVPVVLDVPAPPAPEAPPALGV
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. smegmatis MC2 155 | MSMEG_3499 | - | - | 100% (200) | hypothetical protein MSMEG_3499 |
| M. smegmatis MC2 155 | MSMEG_2146 | - | 5e-15 | 33.33% (177) | gp15 protein |
| M. smegmatis MC2 155 | MSMEG_6285 | - | 2e-10 | 42.86% (84) | DNA polymerase III subunits gamma and tau |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb1145 | - | 1e-58 | 63.10% (168) | hypothetical protein Mb1145 |
| M. gilvum PYR-GCK | Mflv_3272 | - | 1e-72 | 65.52% (203) | hypothetical protein Mflv_3272 |
| M. tuberculosis H37Rv | Rv1115 | - | 1e-58 | 63.10% (168) | hypothetical protein Rv1115 |
| M. leprae Br4923 | MLBr_02395 | Ag36 | 2e-07 | 37.97% (79) | proline rich antigenic protein |
| M. abscessus ATCC 19977 | MAB_4681c | - | 5e-59 | 64.88% (168) | hypothetical protein MAB_4681c |
| M. marinum M | MMAR_4345 | - | 7e-61 | 69.23% (156) | hypothetical protein MMAR_4345 |
| M. avium 104 | MAV_1247 | - | 1e-43 | 59.73% (149) | hypothetical protein MAV_1247 |
| M. thermoresistible (build 8) | TH_1512 | - | 4e-36 | 88.31% (77) | POSSIBLE EXPORTED PROTEIN |
| M. ulcerans Agy99 | MUL_4514 | - | 5e-12 | 44.71% (85) | membrane protein |
| M. vanbaalenii PYR-1 | Mvan_2991 | - | 8e-73 | 70.10% (194) | hypothetical protein Mvan_2991 |
CLUSTAL 2.0.9 multiple sequence alignment
Mflv_3272|M.gilvum_PYR-GCK ----------------------------MFALATLLTLVNQVSGTPYVVG
Mvan_2991|M.vanbaalenii_PYR-1 ------------------------MSVRMFALATLLTLVNQVSGTPYVSG
Mb1145|M.bovis_AF2122/97 ---------MISTTRIDFLWILSVAFAPMIALATLLTLINQVVGTPYIPG
Rv1115|M.tuberculosis_H37Rv ---------MISTTRIDFLWILSVAFASMIALATLLTLINQVVGTPYIPG
MMAR_4345|M.marinum_M ---------MISATNFDFLWILSVASVLMIALATLLTLINQVSGTPYIVG
MSMEG_3499|M.smegmatis_MC2_155 ----------------------------MFALATLMALVQQVSGTPYVSG
TH_1512|M.thermoresistible__bu --------------------------------------------------
MAB_4681c|M.abscessus_ATCC_199 ----------------------------MSDLAALLAFIHQVSGTPYISG
MAV_1247|M.avium_104 --------------------------------------------------
MUL_4514|M.ulcerans_Agy99 MRIGGRWVAHPAVASVRQRALRAKTPVFGIAMITPLVFAGAVGATAPASY
MLBr_02395|M.leprae_Br4923 ---MTDQPPPSGSNPTPAPPPPGSSGGYEPSFAPSELGSAYPPPTAPPVG
Mflv_3272|M.gilvum_PYR-GCK GDS--------------------------------------PSGTDCSGL
Mvan_2991|M.vanbaalenii_PYR-1 GDS--------------------------------------PAGTDCSGL
Mb1145|M.bovis_AF2122/97 GDS--------------------------------------PAGTDCSEL
Rv1115|M.tuberculosis_H37Rv GDS--------------------------------------PAGTDCSEL
MMAR_4345|M.marinum_M GDS--------------------------------------PAGTDCSGL
MSMEG_3499|M.smegmatis_MC2_155 GDS--------------------------------------PSGTDCSGL
TH_1512|M.thermoresistible__bu --------------------------------------------------
MAB_4681c|M.abscessus_ATCC_199 GDT--------------------------------------ARGTDCSGL
MAV_1247|M.avium_104 --------------------------------------------------
MUL_4514|M.ulcerans_Agy99 GKTPAVRAAITPVAAVAPSPAIDLSGPSIVAVERPPTNFHIAAGTTAAPP
MLBr_02395|M.leprae_Br4923 GSYPPPP----------------------------------PPGGSYPPP
Mflv_3272|M.gilvum_PYR-GCK VSWVTNAATGR---------------------------------------
Mvan_2991|M.vanbaalenii_PYR-1 VSWVTNAATGR---------------------------------------
Mb1145|M.bovis_AF2122/97 ASWVSNAATAR---------------------------------------
Rv1115|M.tuberculosis_H37Rv ASWVSNAATAR---------------------------------------
MMAR_4345|M.marinum_M ASWVSNAATDR---------------------------------------
MSMEG_3499|M.smegmatis_MC2_155 ASWVSNVATGR---------------------------------------
TH_1512|M.thermoresistible__bu ---VANVATGR---------------------------------------
MAB_4681c|M.abscessus_ATCC_199 ASWVANVATDR---------------------------------------
MAV_1247|M.avium_104 --------------------------------------------------
MUL_4514|M.ulcerans_Agy99 PARVVNAPGALGIPIMALTAYRNAEQKMATAAPACGISWNLLAGIGRIES
MLBr_02395|M.leprae_Br4923 PPPGGSYPPPP---------------------------------------
Mflv_3272|M.gilvum_PYR-GCK ----------------PVYG------------------------------
Mvan_2991|M.vanbaalenii_PYR-1 ----------------PVYG------------------------------
Mb1145|M.bovis_AF2122/97 ----------------PVFG------------------------------
Rv1115|M.tuberculosis_H37Rv ----------------PVFG------------------------------
MMAR_4345|M.marinum_M ----------------PIFG------------------------------
MSMEG_3499|M.smegmatis_MC2_155 ----------------PAFG------------------------------
TH_1512|M.thermoresistible__bu ----------------PAFG------------------------------
MAB_4681c|M.abscessus_ATCC_199 ----------------PAFG------------------------------
MAV_1247|M.avium_104 -----------------MFG------------------------------
MUL_4514|M.ulcerans_Agy99 MHANGGAVDERGTAVNPIYGPALDGTLPGNEVIIQSKVGNRVTYARAMGP
MLBr_02395|M.leprae_Br4923 ----------------PSTG------------------------------
*
Mflv_3272|M.gilvum_PYR-GCK ------------------------DRFHTGNIESALLARG----------
Mvan_2991|M.vanbaalenii_PYR-1 ------------------------DRFHTGNIESALLARG----------
Mb1145|M.bovis_AF2122/97 ------------------------DRFNTGNEEAALAARG----------
Rv1115|M.tuberculosis_H37Rv ------------------------DRFNTGNEEAALAARG----------
MMAR_4345|M.marinum_M ------------------------DRFNTGNEEAALAARG----------
MSMEG_3499|M.smegmatis_MC2_155 ------------------------DRFHTGNQEQALLARG----------
TH_1512|M.thermoresistible__bu ------------------------DRFHTGNQEAALLARG----------
MAB_4681c|M.abscessus_ATCC_199 ------------------------SRFNTGNQERALLARG----------
MAV_1247|M.avium_104 ------------------------DRFNTGNEEAALLARG----------
MUL_4514|M.ulcerans_Agy99 MQFLPGTWARYASDGDSDGVPDPQNIFDSTLAAARYLCSGGLNLRDPGQV
MLBr_02395|M.leprae_Br4923 ----------------------AYAPPPPGPAIRSLPKEAYTFWVTR---
. .
Mflv_3272|M.gilvum_PYR-GCK ------FQYGTQPGALVVGWNSGHTAVTLPDGTPVSSGE-----------
Mvan_2991|M.vanbaalenii_PYR-1 ------FQYGTQPGALVVGWNRGHTAVTLPDGTPVSSGE-----------
Mb1145|M.bovis_AF2122/97 ------FQQGTAPNALVIGWNGHHTAVTLPDGTPVSSGE-----------
Rv1115|M.tuberculosis_H37Rv ------FQQGTAPNALVIGWNGHHTAVTLPDGTPVSSGE-----------
MMAR_4345|M.marinum_M ------FQHGTAPNALVIGWNGRHTAVTLPDGTSVSSGE-----------
MSMEG_3499|M.smegmatis_MC2_155 ------FKYGTQPGALVIGWNSGHTAVTLPDGTPVSSGE-----------
TH_1512|M.thermoresistible__bu ------FKYGTAPGALVIGWNSTHTAVTLPDGTPVSAGE-----------
MAB_4681c|M.abscessus_ATCC_199 ------FKYGTAPGALVIGWNGGHTAVTLPDGTAVSSGE-----------
MAV_1247|M.avium_104 ------FQYGTAPNALVIGWNGGHTAVTLPDGTAVSSGE-----------
MUL_4514|M.ulcerans_Agy99 MAAILRYNNSMPYAQNVLGWAAAYATGVLPVDLPPITGPPPPIGDAHLEH
MLBr_02395|M.leprae_Br4923 ---VLAYVIDNIPATVLLGIGMLIQTLTKQEACVTDITQYN-------VN
: . ::* : .
Mflv_3272|M.gilvum_PYR-GCK ----GGGVRVGGGGAYQDQFTNHMFLP--APAAVPPPPDPFL--------
Mvan_2991|M.vanbaalenii_PYR-1 ----GGGVKIGGGGAYQEQFTNHMFLP--APAEAVPAPDPVL--------
Mb1145|M.bovis_AF2122/97 ----GGGVRVGGGGAYQPKFTHHMYLP--MDVDAGEDQPPAP--------
Rv1115|M.tuberculosis_H37Rv ----GGGVRVGGGGAYQPKFTHHMYLP--MDVDAGEDQPPAP--------
MMAR_4345|M.marinum_M ----GGGVRVGGGGAYQAQFTHHMYLP--MDEDMVDVDLPAP--------
MSMEG_3499|M.smegmatis_MC2_155 ----GGGVKIGGGGAYQPQFNHHMYLP--AEEVQPDAGLPV---------
TH_1512|M.thermoresistible__bu ----GGGVKIGGGGAFXXPFG-----------------------------
MAB_4681c|M.abscessus_ATCC_199 ----GGGVRIGGGGAYQPQFKRHMYLP--MDSDDAAGSAPL---------
MAV_1247|M.avium_104 ----HGGVHVGGAGAYQAGFTHHMFLP--MPPEDGGAPPPAM--------
MUL_4514|M.ulcerans_Agy99 PEGLGPNLPLNANGLEPADPLSHMPLIDFAPPQMPAPPPPMFPWMQPTPQ
MLBr_02395|M.leprae_Br4923 QYCATQPTGIGMLAFWFAWLMATAYLVWNYGYRQGATGSSIG--------
:. .
Mflv_3272|M.gilvum_PYR-GCK -------------------------------SPPINQLPPPP--------
Mvan_2991|M.vanbaalenii_PYR-1 -------------------------------APPMSPFPPPPGAVPPPP-
Mb1145|M.bovis_AF2122/97 -------------------------------DEPVTAVDDVEPEMPAPC-
Rv1115|M.tuberculosis_H37Rv -------------------------------DEPVTAVDDVEPEMPAPC-
MMAR_4345|M.marinum_M -------------------------------EDPPAVEDVVNPDELPP--
MSMEG_3499|M.smegmatis_MC2_155 -------------------------------GAPPPPEASLPPLPPPPA-
TH_1512|M.thermoresistible__bu --------------------------------------------------
MAB_4681c|M.abscessus_ATCC_199 -------------------------------DVPADAEG-----------
MAV_1247|M.avium_104 -------------------------------FGPPPPPDAPPP-------
MUL_4514|M.ulcerans_Agy99 PLAPQPGCTLICVTNPPEAVPPPAPMPFGLMPPPPAPAAPPPPDPLAPLG
MLBr_02395|M.leprae_Br4923 --------------------------------KTVMKFKVISEATGQPIG
Mflv_3272|M.gilvum_PYR-GCK -------PPGAAPVVMMG--------HETALPPGAPLPPPPPGAPVPPPP
Mvan_2991|M.vanbaalenii_PYR-1 ------PPPPAGPVVLMG--------QQAPVPP-------PPGAPVPPPP
Mb1145|M.bovis_AF2122/97 ------PTQRPPVTPRHNLCNKLRTMPGALSAALAAAAPVWPAPISGCRG
Rv1115|M.tuberculosis_H37Rv ------PTQRPPVTPRHNLCNKLRTMPGALSAALAAAAPVWPAPISGCRG
MMAR_4345|M.marinum_M ----------PPEDP----------------------GPVDDLEISNT--
MSMEG_3499|M.smegmatis_MC2_155 ------DPMAPAPPM------------AGPPPVDPFAPPPPPEPAVVPVV
TH_1512|M.thermoresistible__bu --------------------------------------------------
MAB_4681c|M.abscessus_ATCC_199 -------------------------------------PEVIPASVLVPQP
MAV_1247|M.avium_104 ------PPDAPAPPP--------------------DAPPAPPEAPAVLID
MUL_4514|M.ulcerans_Agy99 VPPVGGPPAAPAPAPAGPPVPGGPAPAGPAPAPAGPAPAPGAPAPAGPAP
MLBr_02395|M.leprae_Br4923 -------FGMSVVRQLAH-------FVDAVICCIGFLFPLWDSKRQTLAD
Mflv_3272|M.gilvum_PYR-GCK PGMPVPPPPPGAPA----
Mvan_2991|M.vanbaalenii_PYR-1 -GAPVPPAP---------
Mb1145|M.bovis_AF2122/97 FSTSLLAKRNHPVIVGK-
Rv1115|M.tuberculosis_H37Rv FSTSLLAKRNHPVIVGK-
MMAR_4345|M.marinum_M ------------------
MSMEG_3499|M.smegmatis_MC2_155 LDVPAPPAPEAPPALGV-
TH_1512|M.thermoresistible__bu ------------------
MAB_4681c|M.abscessus_ATCC_199 ESVPADEAPAQVAPVEI-
MAV_1247|M.avium_104 APAPVPPPPPGP------
MUL_4514|M.ulcerans_Agy99 TPTPSGPAPGEPVLTPVH
MLBr_02395|M.leprae_Br4923 KIMTTVCLPI--------