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VRMAQAPLSGKTMFISGASRGIGLAIAKRAAADGANIALIAKTAEPHPKLEGTIYTAAEEIEDAGGQALP IVGDVRDGDSVAAAVTKAVEQFGGIDICVNNASAINLGSIEEVPLKRFDLMNGIQIRGTYAVSQACIPHM KGRENPHILTLSPPVRLEPEWLKPTAYMMAKFGMTLCALGIAEEMREHGIASNTLWPRTLVATAAVQNLL GGDEAMARARKPQVYADAAYAVFTKPAREFTGNTLLCEDVLLDSGVTDLSVYDCVPGGELGVDLWVDTPN PPGYTGP*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. smegmatis MC2 155 | MSMEG_1894 | - | - | 100% (288) | short chain dehydrogenase |
| M. smegmatis MC2 155 | MSMEG_4882 | - | 4e-68 | 47.52% (282) | short chain dehydrogenase |
| M. smegmatis MC2 155 | MSMEG_4872 | - | 3e-34 | 40.09% (222) | short chain dehydrogenase |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb3251 | - | 1e-138 | 84.48% (277) | short chain dehydrogenase |
| M. gilvum PYR-GCK | Mflv_4691 | - | 1e-142 | 86.07% (280) | short chain dehydrogenase |
| M. tuberculosis H37Rv | Rv3224 | - | 1e-138 | 84.48% (277) | short chain dehydrogenase |
| M. leprae Br4923 | MLBr_01807 | fabG1 | 3e-08 | 23.27% (202) | 3-oxoacyl- |
| M. abscessus ATCC 19977 | MAB_3946c | - | 4e-87 | 57.35% (272) | putative short chain dehydrogenase/reductase |
| M. marinum M | MMAR_1333 | - | 1e-140 | 85.00% (280) | iron-regulated short-chain dehydrogenase/reductase |
| M. avium 104 | MAV_4172 | - | 1e-141 | 86.79% (280) | short chain dehydrogenase |
| M. thermoresistible (build 8) | TH_0664 | - | 1e-144 | 86.79% (280) | POSSIBLE IRON-REGULATED SHORT-CHAIN DEHYDROGENASE/REDUCTASE |
| M. ulcerans Agy99 | MUL_2546 | - | 1e-139 | 84.64% (280) | short chain dehydrogenase |
| M. vanbaalenii PYR-1 | Mvan_1776 | - | 1e-142 | 86.79% (280) | short chain dehydrogenase |
CLUSTAL 2.0.9 multiple sequence alignment
Mflv_4691|M.gilvum_PYR-GCK ------MSLAGKTMFISGASRGIGLAIAKRAAADGANIALVAKTAEPHPK
Mvan_1776|M.vanbaalenii_PYR-1 ------MSLAGKTMFISGASRGIGLAIAKRAAADGANIALVAKTAEPHPK
TH_0664|M.thermoresistible__bu ------MSLRGKTMFISGGSRGIGLAIAKRVAADGANVALVAKSAEPHPK
MSMEG_1894|M.smegmatis_MC2_155 MVRMAQAPLSGKTMFISGASRGIGLAIAKRAAADGANIALIAKTAEPHPK
Mb3251|M.bovis_AF2122/97 ------MSLNGKTMFISGASRGIGLAIAKRAARDGANIALIAKTAEPHPK
Rv3224|M.tuberculosis_H37Rv ------MSLNGKTMFISGASRGIGLAIAKRAARDGANIALIAKTAEPHPK
MMAR_1333|M.marinum_M ------MSLNGKTMFISGASRGIGLAIAKRAAQDGANIALIAKTAEPHPK
MUL_2546|M.ulcerans_Agy99 ------MSLNGKTMFISGASRGIGLAIAKRAAQDGANIALIAKTAEPHPK
MAV_4172|M.avium_104 ------MSLNGKTMFISGASRGIGLAIAKRAAQDGANIALIAKTAEPHPK
MAB_3946c|M.abscessus_ATCC_199 -----MGSLAGKTIIMSGGSRGIGLAIALRAARDGANVAIMAKTAEPHPK
MLBr_01807|M.leprae_Br4923 -------MTDAAAKVSAAPGRGKPAFVSRSILVTGGNRGIGLAVAR-RLV
. : . :. .** :: *.* .: *. :
Mflv_4691|M.gilvum_PYR-GCK LPGTVYTAAEEIEEAGGQALPIVGDVRDGDSVVAAVAQAVEKFGGIDICV
Mvan_1776|M.vanbaalenii_PYR-1 LPGTVYTAAKEIEEVGGQALPIVGDVRDGDSVAAAVAKTVEQFGGIDMCV
TH_0664|M.thermoresistible__bu LPGTIYTAAKEIEEAGGQALPIVGDIRDGDAVAAAVAKTVEQFGGIDICV
MSMEG_1894|M.smegmatis_MC2_155 LEGTIYTAAEEIEDAGGQALPIVGDVRDGDSVAAAVTKAVEQFGGIDICV
Mb3251|M.bovis_AF2122/97 LPGTVFTAAKELEEAGGQALPIVGDIRDPDAVASAVATTVEQFGGIDICV
Rv3224|M.tuberculosis_H37Rv LPGTVFTAAKELEEAGGQALPIVGDIRDPDAVASAVATTVEQFGGIDICV
MMAR_1333|M.marinum_M LPGTVYTAAKELEEAGGQALPIVGDVRDPDSVSAAVAKTVEQFGGIDICV
MUL_2546|M.ulcerans_Agy99 LPGTVYTAAKELEEAGGQALPIVGDVRDPDSVSAAVAKTVEQFGGIDICV
MAV_4172|M.avium_104 LPGTVYTAAKELEEAGGQALPIVGDVRDPESVEAAVAKTVEQFGGIDICV
MAB_3946c|M.abscessus_ATCC_199 LPGTIYTAAEEIEAAGGHALPLLGDVRDDEVVASAVAQTVEKFGGIDIVV
MLBr_01807|M.leprae_Br4923 ADGHRVAVTHRASVVPDWFFGVECDVTDNDAIGAAFKAVEEHQGPVEVLV
* :.:.. . . . : : *: * : : :*. . *: * ::: *
Mflv_4691|M.gilvum_PYR-GCK NNASAINLGSIEDVPLKRFDLMNGIQVRGTYAVSQACIPHMKGRDNPHIL
Mvan_1776|M.vanbaalenii_PYR-1 NNASAINLGSIEEVPLKRFDLMNGIQVRGTYAVSQACIPHMKGRDNPHIL
TH_0664|M.thermoresistible__bu NNASAINLGSIEEVPLKRFDLMNGIQVRGTYAVSQSCIPHMKGRDNPHIL
MSMEG_1894|M.smegmatis_MC2_155 NNASAINLGSIEEVPLKRFDLMNGIQIRGTYAVSQACIPHMKGRENPHIL
Mb3251|M.bovis_AF2122/97 NNASAINLGSITEVPMKRFDLMNGIQVRGTYAVSQACIPHMKGRENPHIL
Rv3224|M.tuberculosis_H37Rv NNASAINLGSITEVPMKRFDLMNGIQVRGTYAVSQACIPHMKGRENPHIL
MMAR_1333|M.marinum_M NNASAINLGSITEVPMKRFDLMNGIQVRGTYAVSQACIPHLKGRENPHIL
MUL_2546|M.ulcerans_Agy99 NNASAINLGSITEVPMKRFDLMNGIQVRGTYAVSQACIPHLKGRENPHIL
MAV_4172|M.avium_104 NNASAINLGPITEVPMKRFDLMNGIQVRGTYAVSQACIPHLKGRENPHIL
MAB_3946c|M.abscessus_ATCC_199 NNASALNLAPSESISMKAYDLMQDINARGSFSLSTSAIGALKEADNPHIL
MLBr_01807|M.leprae_Br4923 ANAGITSDMLIMRMSEEQFQKVIDVNLTGVFRVAKLASRNMIKQRFGRYI
**. . :. : :: : .:: * : :: . : : :
Mflv_4691|M.gilvum_PYR-GCK TLSPPILLESKWLR--PTPYMMAKFGMTLCALGIAEELRDARVASNTLWP
Mvan_1776|M.vanbaalenii_PYR-1 TLSPPILLESKWLR--PTPYMMAKFGMTLCALGIAEEMRDAGIASNTLWP
TH_0664|M.thermoresistible__bu TLSPPIRLEPKWLR--PTPYMMAKYGMTLCALGIAEELRDAGIASNTLWP
MSMEG_1894|M.smegmatis_MC2_155 TLSPPVRLEPEWLK--PTAYMMAKFGMTLCALGIAEEMREHGIASNTLWP
Mb3251|M.bovis_AF2122/97 TLSPPILLEKKWLR--PTAYMMAKYGMTLCALGIAEEMRADGIASNTLWP
Rv3224|M.tuberculosis_H37Rv TLSPPILLEKKWLR--PTAYMMAKYGMTLCALGIAEEMRADGIASNTLWP
MMAR_1333|M.marinum_M TLSPPVQLDKKWLK--PTAYMMAKFGMTLCALGIAEEMRDEGIASNTLWP
MUL_2546|M.ulcerans_Agy99 TLSPPVQLDKKWLK--PTAYMMAKFGMTLCALGIAEEMRDEGIASNTLWP
MAV_4172|M.avium_104 TLSPPVLLGKEWLK--PTAYMMAKFGMTLCALGIAEEMREAGIASNTLWP
MAB_3946c|M.abscessus_ATCC_199 TLSPPITLEPKWFERTTTAYTISKFSMSLVAIGLAAELRQYGIASNALWP
MLBr_01807|M.leprae_Br4923 FMGSVVGLSGVPGQ---ANYAASKSGLIGMARSLARELGSRSITANVVAP
:.. : * . : * :* .: * .:* *: :::*.: *
Mflv_4691|M.gilvum_PYR-GCK RTMVATAAVQNLLGGDESMARSRKPEVYSDAAYAILTKPS-SFTGNTLLC
Mvan_1776|M.vanbaalenii_PYR-1 RTMVATAAVQNLLGGDESMARSRKPEVYSDAAYAVLTKPS-SFTGHTLLC
TH_0664|M.thermoresistible__bu RTTVATAAVQNLLGGDEAMARSRKPEVYADAAYVVLNKPS-SYTGNTLLC
MSMEG_1894|M.smegmatis_MC2_155 RTLVATAAVQNLLGGDEAMARARKPQVYADAAYAVFTKPAREFTGNTLLC
Mb3251|M.bovis_AF2122/97 RTMVATAAVQNLLGGDEAMARSRKPEVYADAAYVIVNKPATEYTGKTLLC
Rv3224|M.tuberculosis_H37Rv RTMVATAAVQNLLGGDEAMARSRKPEVYADAAYVIVNKPATEYTGKTLLC
MMAR_1333|M.marinum_M RTLVATAAVQNLLGGDEAMGRARKPDVYADAAYVILNKNSREYTGNSALC
MUL_2546|M.ulcerans_Agy99 RTLVATAAVQNLLGGEEAMGRARKPDVYADAAYVILNKNSREYTGNSALC
MAV_4172|M.avium_104 RTLVATAAVQNLLGGDEAMGRARKPEVYSDAAYVILNKPAREFTGNMLLC
MAB_3946c|M.abscessus_ATCC_199 RTTIDTAAIRNILG-AELVARCRSAQIMADAAYEILTKPSREVSGNCFID
MLBr_01807|M.leprae_Br4923 -GFIDTEMTR------------AMDSKYQEAALQAIPLGRIGAVEEIAGA
: * : . :** . .
Mflv_4691|M.gilvum_PYR-GCK EDVLLEAGVTDLSVYDCVPGSELGVDFWVDSANPPGYTGP
Mvan_1776|M.vanbaalenii_PYR-1 EDVLLESGVTDLSVYDCVPGSDLGVDFWVEGANPPGYTGP
TH_0664|M.thermoresistible__bu EDVLLESGVTDLSVYDCVPGSELGVDLWVDSPNPPGYTGP
MSMEG_1894|M.smegmatis_MC2_155 EDVLLDSGVTDLSVYDCVPGGELGVDLWVDTPNPPGYTGP
Mb3251|M.bovis_AF2122/97 EDVLVESGVTDLSVYDCVPGATLGVDLWVEDANPPGYLPA
Rv3224|M.tuberculosis_H37Rv EDVLVESGVTDLSVYDCVPGATLGVDLWVEDANPPGYLPA
MMAR_1333|M.marinum_M EDVLLESGVSDLSIYNCVPGAKLGVDLWVEEVNPPGYTQP
MUL_2546|M.ulcerans_Agy99 EDVLLESGVSDLSIYNCVPGAKLGVDLWVEEVNPPGYTQP
MAV_4172|M.avium_104 EDVLVESGVTDLSVYNCVPGSQLGVDFWVDGVNPPGYTGP
MAB_3946c|M.abscessus_ATCC_199 DEVLREAGVTDFSQYRECAEEDLELDFWMERA--------
MLBr_01807|M.leprae_Br4923 VSFLASEDAGYISGAVIPVDGGLGMGH-------------
..* . .. :* * :.