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M. thermoresistible (build 8) TH_0664 ()

annotation: POSSIBLE IRON-REGULATED SHORT-CHAIN DEHYDROGENASE/REDUCTASE
coordinates: 1428512 - 1429357
length: 282

aa seq not available

Operon Prediction Model: Genebank

Paralogs

species id gene e-value identity (len) annotation
M. thermoresistible (build 8) TH_0664 - 100% (282) POSSIBLE IRON-REGULATED SHORT-CHAIN DEHYDROGENASE/REDUCTASE
M. thermoresistible (build 8) TH_0126 - 4e-70 49.64% (276) POSSIBLE IRON-REGULATED SHORT-CHAIN DEHYDROGENASE/REDUCTASE
M. thermoresistible (build 8) TH_2687 - 4e-50 42.42% (231) PUTATIVE short-chain dehydrogenase/reductase SDR

Closest Orthologs (e-value cutoff: 1e-4)

species id gene e-value identity (len) annotation
M. bovis AF2122 / 97 Mb3251 - 1e-141 87.10% (279) short chain dehydrogenase
M. gilvum PYR-GCK Mflv_4691 - 1e-148 89.32% (281) short chain dehydrogenase
M. tuberculosis H37Rv Rv3224 - 1e-141 87.10% (279) short chain dehydrogenase
M. leprae Br4923 MLBr_01807 fabG1 7e-09 24.62% (195) 3-oxoacyl-
M. abscessus ATCC 19977 MAB_3946c - 2e-87 58.97% (273) putative short chain dehydrogenase/reductase
M. marinum M MMAR_1333 - 1e-139 83.69% (282) iron-regulated short-chain dehydrogenase/reductase
M. avium 104 MAV_4172 - 1e-139 83.69% (282) short chain dehydrogenase
M. smegmatis MC2 155 MSMEG_1894 - 1e-144 86.79% (280) short chain dehydrogenase
M. ulcerans Agy99 MUL_2546 - 1e-139 83.33% (282) short chain dehydrogenase
M. vanbaalenii PYR-1 Mvan_1776 - 1e-149 90.39% (281) short chain dehydrogenase

CLUSTAL 2.0.9 multiple sequence alignment


Mb3251|M.bovis_AF2122/97            ------MSLNGKTMFISGASRGIGLAIAKRAARDGANIALIAKTAEPHPK
Rv3224|M.tuberculosis_H37Rv         ------MSLNGKTMFISGASRGIGLAIAKRAARDGANIALIAKTAEPHPK
MMAR_1333|M.marinum_M               ------MSLNGKTMFISGASRGIGLAIAKRAAQDGANIALIAKTAEPHPK
MUL_2546|M.ulcerans_Agy99           ------MSLNGKTMFISGASRGIGLAIAKRAAQDGANIALIAKTAEPHPK
MAV_4172|M.avium_104                ------MSLNGKTMFISGASRGIGLAIAKRAAQDGANIALIAKTAEPHPK
Mflv_4691|M.gilvum_PYR-GCK          ------MSLAGKTMFISGASRGIGLAIAKRAAADGANIALVAKTAEPHPK
Mvan_1776|M.vanbaalenii_PYR-1       ------MSLAGKTMFISGASRGIGLAIAKRAAADGANIALVAKTAEPHPK
TH_0664|M.thermoresistible__bu      ------MSLRGKTMFISGGSRGIGLAIAKRVAADGANVALVAKSAEPHPK
MSMEG_1894|M.smegmatis_MC2_155      MVRMAQAPLSGKTMFISGASRGIGLAIAKRAAADGANIALIAKTAEPHPK
MAB_3946c|M.abscessus_ATCC_199      -----MGSLAGKTIIMSGGSRGIGLAIALRAARDGANVAIMAKTAEPHPK
MLBr_01807|M.leprae_Br4923          -------MTDAAAKVSAAPGRGKPAFVSRSILVTGGNRGIGLAVAR-RLV
                                              . : . :. .**    ::      *.* .:    *. :  

Mb3251|M.bovis_AF2122/97            LPGTVFTAAKELEEAGGQALPIVGDIRDPDAVASAVATTVEQFGGIDICV
Rv3224|M.tuberculosis_H37Rv         LPGTVFTAAKELEEAGGQALPIVGDIRDPDAVASAVATTVEQFGGIDICV
MMAR_1333|M.marinum_M               LPGTVYTAAKELEEAGGQALPIVGDVRDPDSVSAAVAKTVEQFGGIDICV
MUL_2546|M.ulcerans_Agy99           LPGTVYTAAKELEEAGGQALPIVGDVRDPDSVSAAVAKTVEQFGGIDICV
MAV_4172|M.avium_104                LPGTVYTAAKELEEAGGQALPIVGDVRDPESVEAAVAKTVEQFGGIDICV
Mflv_4691|M.gilvum_PYR-GCK          LPGTVYTAAEEIEEAGGQALPIVGDVRDGDSVVAAVAQAVEKFGGIDICV
Mvan_1776|M.vanbaalenii_PYR-1       LPGTVYTAAKEIEEVGGQALPIVGDVRDGDSVAAAVAKTVEQFGGIDMCV
TH_0664|M.thermoresistible__bu      LPGTIYTAAKEIEEAGGQALPIVGDIRDGDAVAAAVAKTVEQFGGIDICV
MSMEG_1894|M.smegmatis_MC2_155      LEGTIYTAAEEIEDAGGQALPIVGDVRDGDSVAAAVTKAVEQFGGIDICV
MAB_3946c|M.abscessus_ATCC_199      LPGTIYTAAEEIEAAGGHALPLLGDVRDDEVVASAVAQTVEKFGGIDIVV
MLBr_01807|M.leprae_Br4923          ADGHRVAVTHRASVVPDWFFGVECDVTDNDAIGAAFKAVEEHQGPVEVLV
                                      *   :.:.. . . .  : :  *: * : : :*.  . *: * ::: *

Mb3251|M.bovis_AF2122/97            NNASAINLGSITEVPMKRFDLMNGIQVRGTYAVSQACIPHMKGRENPHIL
Rv3224|M.tuberculosis_H37Rv         NNASAINLGSITEVPMKRFDLMNGIQVRGTYAVSQACIPHMKGRENPHIL
MMAR_1333|M.marinum_M               NNASAINLGSITEVPMKRFDLMNGIQVRGTYAVSQACIPHLKGRENPHIL
MUL_2546|M.ulcerans_Agy99           NNASAINLGSITEVPMKRFDLMNGIQVRGTYAVSQACIPHLKGRENPHIL
MAV_4172|M.avium_104                NNASAINLGPITEVPMKRFDLMNGIQVRGTYAVSQACIPHLKGRENPHIL
Mflv_4691|M.gilvum_PYR-GCK          NNASAINLGSIEDVPLKRFDLMNGIQVRGTYAVSQACIPHMKGRDNPHIL
Mvan_1776|M.vanbaalenii_PYR-1       NNASAINLGSIEEVPLKRFDLMNGIQVRGTYAVSQACIPHMKGRDNPHIL
TH_0664|M.thermoresistible__bu      NNASAINLGSIEEVPLKRFDLMNGIQVRGTYAVSQSCIPHMKGRDNPHIL
MSMEG_1894|M.smegmatis_MC2_155      NNASAINLGSIEEVPLKRFDLMNGIQIRGTYAVSQACIPHMKGRENPHIL
MAB_3946c|M.abscessus_ATCC_199      NNASALNLAPSESISMKAYDLMQDINARGSFSLSTSAIGALKEADNPHIL
MLBr_01807|M.leprae_Br4923          ANAGITSDMLIMRMSEEQFQKVIDVNLTGVFRVAKLASRNMIKQRFGRYI
                                     **.  .      :. : :: : .::  * : ::  .   :      : :

Mb3251|M.bovis_AF2122/97            TLSPPILLEKKWLR--PTAYMMAKYGMTLCALGIAEEMRADGIASNTLWP
Rv3224|M.tuberculosis_H37Rv         TLSPPILLEKKWLR--PTAYMMAKYGMTLCALGIAEEMRADGIASNTLWP
MMAR_1333|M.marinum_M               TLSPPVQLDKKWLK--PTAYMMAKFGMTLCALGIAEEMRDEGIASNTLWP
MUL_2546|M.ulcerans_Agy99           TLSPPVQLDKKWLK--PTAYMMAKFGMTLCALGIAEEMRDEGIASNTLWP
MAV_4172|M.avium_104                TLSPPVLLGKEWLK--PTAYMMAKFGMTLCALGIAEEMREAGIASNTLWP
Mflv_4691|M.gilvum_PYR-GCK          TLSPPILLESKWLR--PTPYMMAKFGMTLCALGIAEELRDARVASNTLWP
Mvan_1776|M.vanbaalenii_PYR-1       TLSPPILLESKWLR--PTPYMMAKFGMTLCALGIAEEMRDAGIASNTLWP
TH_0664|M.thermoresistible__bu      TLSPPIRLEPKWLR--PTPYMMAKYGMTLCALGIAEELRDAGIASNTLWP
MSMEG_1894|M.smegmatis_MC2_155      TLSPPVRLEPEWLK--PTAYMMAKFGMTLCALGIAEEMREHGIASNTLWP
MAB_3946c|M.abscessus_ATCC_199      TLSPPITLEPKWFERTTTAYTISKFSMSLVAIGLAAELRQYGIASNALWP
MLBr_01807|M.leprae_Br4923          FMGSVVGLSGVPGQ---ANYAASKSGLIGMARSLARELGSRSITANVVAP
                                     :.. : *     .   : *  :* .:   * .:* *:    :::*.: *

Mb3251|M.bovis_AF2122/97            RTMVATAAVQNLLGGDEAMARSRKPEVYADAAYVIVNKPATEYTGKTLLC
Rv3224|M.tuberculosis_H37Rv         RTMVATAAVQNLLGGDEAMARSRKPEVYADAAYVIVNKPATEYTGKTLLC
MMAR_1333|M.marinum_M               RTLVATAAVQNLLGGDEAMGRARKPDVYADAAYVILNKNSREYTGNSALC
MUL_2546|M.ulcerans_Agy99           RTLVATAAVQNLLGGEEAMGRARKPDVYADAAYVILNKNSREYTGNSALC
MAV_4172|M.avium_104                RTLVATAAVQNLLGGDEAMGRARKPEVYSDAAYVILNKPAREFTGNMLLC
Mflv_4691|M.gilvum_PYR-GCK          RTMVATAAVQNLLGGDESMARSRKPEVYSDAAYAILTKPS-SFTGNTLLC
Mvan_1776|M.vanbaalenii_PYR-1       RTMVATAAVQNLLGGDESMARSRKPEVYSDAAYAVLTKPS-SFTGHTLLC
TH_0664|M.thermoresistible__bu      RTTVATAAVQNLLGGDEAMARSRKPEVYADAAYVVLNKPS-SYTGNTLLC
MSMEG_1894|M.smegmatis_MC2_155      RTLVATAAVQNLLGGDEAMARARKPQVYADAAYAVFTKPAREFTGNTLLC
MAB_3946c|M.abscessus_ATCC_199      RTTIDTAAIRNILG-AELVARCRSAQIMADAAYEILTKPSREVSGNCFID
MLBr_01807|M.leprae_Br4923          -GFIDTEMTR------------AMDSKYQEAALQAIPLGRIGAVEEIAGA
                                       : *   :               .   :**   .         .    

Mb3251|M.bovis_AF2122/97            EDVLVESGVTDLSVYDCVPGATLGVDLWVEDANPPGYLPA
Rv3224|M.tuberculosis_H37Rv         EDVLVESGVTDLSVYDCVPGATLGVDLWVEDANPPGYLPA
MMAR_1333|M.marinum_M               EDVLLESGVSDLSIYNCVPGAKLGVDLWVEEVNPPGYTQP
MUL_2546|M.ulcerans_Agy99           EDVLLESGVSDLSIYNCVPGAKLGVDLWVEEVNPPGYTQP
MAV_4172|M.avium_104                EDVLVESGVTDLSVYNCVPGSQLGVDFWVDGVNPPGYTGP
Mflv_4691|M.gilvum_PYR-GCK          EDVLLEAGVTDLSVYDCVPGSELGVDFWVDSANPPGYTGP
Mvan_1776|M.vanbaalenii_PYR-1       EDVLLESGVTDLSVYDCVPGSDLGVDFWVEGANPPGYTGP
TH_0664|M.thermoresistible__bu      EDVLLESGVTDLSVYDCVPGSELGVDLWVDSPNPPGYTGP
MSMEG_1894|M.smegmatis_MC2_155      EDVLLDSGVTDLSVYDCVPGGELGVDLWVDTPNPPGYTGP
MAB_3946c|M.abscessus_ATCC_199      DEVLREAGVTDFSQYRECAEEDLELDFWMERA--------
MLBr_01807|M.leprae_Br4923          VSFLASEDAGYISGAVIPVDGGLGMGH-------------
                                     ..* . ..  :*         * :.

species	id	gene	e-value	identity (len)	annotation
M. thermoresistible (build 8)	TH_0664		-	100% (282)	POSSIBLE IRON-REGULATED SHORT-CHAIN DEHYDROGENASE/REDUCTASE
M. thermoresistible (build 8)	TH_0126	-	4e-70	49.64% (276)	POSSIBLE IRON-REGULATED SHORT-CHAIN DEHYDROGENASE/REDUCTASE
M. thermoresistible (build 8)	TH_2687	-	4e-50	42.42% (231)	PUTATIVE short-chain dehydrogenase/reductase SDR