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MTALLNTPVSGSSSPGASPELAPELVRETLARSILADGFDFVLDLEESRGSHLVDARTGERFLDMFTFFA SSALGMNHSALADDPEFRAELAQAALNKPSNSDIYSVPMARFVDTFRRVLGDPALPHLFFVDGGALAVEN ALKVAFDWKSRHNEAHGIDPELGTKVLHLRGAFHGRSGYTLSLTNTDPVKVARFPKFDWPRIDAPYVRPG LDDDAMAALEAESLRQARAAFEAHPHDIACFIAEPIQGEGGDRHFRPEFFAAMRELCDEFDALLIFDEVQ TGCGITGTAWAYQQLGVMPDVVSFGKKTQVCGVMAGRRVDEVADNVFAVSSRINSTWGGNLVDMVRSRRI LEVIERDGLLDNARDMGAYLLDELRVLATRFPGVVVDPRGRGLMCAFSMPTPEDRDALIRKLWDRHVIML PSGADSVRFRPALPVTRAEIDACLDAVRAVLSER
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. smegmatis MC2 155 | MSMEG_1764 | - | - | 100% (454) | L-lysine aminotransferase |
| M. smegmatis MC2 155 | MSMEG_3900 | ectB | 6e-24 | 27.51% (418) | diaminobutyrate--2-oxoglutarate aminotransferase |
| M. smegmatis MC2 155 | MSMEG_2487 | - | 6e-24 | 28.07% (424) | 4-aminobutyrate aminotransferase |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb3318c | lat | 0.0 | 79.25% (429) | L-lysine aminotransferase |
| M. gilvum PYR-GCK | Mflv_4796 | - | 0.0 | 81.21% (431) | L-lysine aminotransferase |
| M. tuberculosis H37Rv | Rv3290c | lat | 0.0 | 79.25% (429) | L-lysine aminotransferase |
| M. leprae Br4923 | MLBr_01409 | argD | 2e-23 | 27.00% (400) | acetylornithine aminotransferase |
| M. abscessus ATCC 19977 | MAB_3646c | - | 0.0 | 74.78% (448) | L-lysine aminotransferase |
| M. marinum M | MMAR_1243 | lat | 0.0 | 76.36% (440) | L-lysine-epsilon aminotransferase Lat |
| M. avium 104 | MAV_4262 | - | 0.0 | 77.16% (451) | L-lysine aminotransferase |
| M. thermoresistible (build 8) | TH_3246 | - | 3e-26 | 27.87% (427) | PUTATIVE diaminobutyrate--2-oxoglutarate aminotransferase |
| M. ulcerans Agy99 | MUL_2644 | lat | 0.0 | 76.36% (440) | L-lysine aminotransferase |
| M. vanbaalenii PYR-1 | Mvan_1652 | - | 0.0 | 78.75% (447) | L-lysine aminotransferase |
CLUSTAL 2.0.9 multiple sequence alignment
Mflv_4796|M.gilvum_PYR-GCK ---------MTAVLSRAD--RTAVIVPADVRTVLSRSILADGLDLVLDLE
Mvan_1652|M.vanbaalenii_PYR-1 ------MPLHASVRPEADA-ETDRLGPDDVHHVLARSILADGLDLVLDID
MSMEG_1764|M.smegmatis_MC2_155 ----MTALLNTPVSGSSSPGASPELAPELVRETLARSILADGFDFVLDLE
Mb3318c|M.bovis_AF2122/97 ---------MAAVVKSVAL-AGRPTTPDRVHEVLGRSMLVDGLDIVLDLT
Rv3290c|M.tuberculosis_H37Rv ---------MAAVVKSVAL-AGRPTTPDRVHEVLGRSMLVDGLDIVLDLT
MMAR_1243|M.marinum_M ---------MTAAVRSTVP-ACQQIEADDVQEVLGRSMLVDGFDLVLDLS
MUL_2644|M.ulcerans_Agy99 ---------MTAAVRSTVP-ACQQIEADDIQEVLGRSMLVDGFDLVLDLS
MAV_4262|M.avium_104 ---------MTAALERLAR-ARSCTGPDRVHEVLSRSILTDGFDFVLDLD
MAB_3646c|M.abscessus_ATCC_199 MTALIFPGFQAGPTHGDQATRPDPVTPDRVHDVLRRSILADGMDLVLDLE
MLBr_01409|M.leprae_Br4923 --------------------MTPTQTNTATMQQRWETVMMNNYGTPPIVL
TH_3246|M.thermoresistible__bu ---------------MSLLATTSETELPEVFSTIESEVRSYCRGWPAVME
: . :
Mflv_4796|M.gilvum_PYR-GCK RSHGSYLVDARTGRGYLDMFTFFASSALGMNHPALADDPDFRAELAAAAV
Mvan_1652|M.vanbaalenii_PYR-1 RSHGSHLVDARTGRSYLDMFTFFASSALGMNHPGLAGDPEFRAELAAAAL
MSMEG_1764|M.smegmatis_MC2_155 ESRGSHLVDARTGERFLDMFTFFASSALGMNHSALADDPEFRAELAQAAL
Mb3318c|M.bovis_AF2122/97 RSGGSYLVDAITGRRYLDMFTFVASSALGMNPPALVDDREFHAELMQAAL
Rv3290c|M.tuberculosis_H37Rv RSGGSYLVDAITGRRYLDMFTFVASSALGMNPPALVDDREFHAELMQAAL
MMAR_1243|M.marinum_M QSAGSYLVDARTGRRYLDMFTFFASSALGMNHPGLAEDEQFRAELLEAAL
MUL_2644|M.ulcerans_Agy99 QSAGSYLVDARTGRRYLDMFTFFASSALGMNHPGLAEDEQFRAELLEAAL
MAV_4262|M.avium_104 RSRGSVLYDARDGRRYLDMFTFFASSALGMNHPALARDAEFRAELTAAAL
MAB_3646c|M.abscessus_ATCC_199 RSHGAHLVDARDGTDYLDMFTFFASSALGMNHPMLAEDDEFRAELATAAI
MLBr_01409|M.leprae_Br4923 ASGNGAVVTDVDSNTYLDLLGGIAVNVLGHRHPAVIEAVTHQITTLGHTS
TH_3246|M.thermoresistible__bu SARGSWITDVS-GQRYLDFFAGAGALNYGHNNPKLKEP----LLKYLMSD
: .. : . :**:: . * . . : :
Mflv_4796|M.gilvum_PYR-GCK NKPSNSDVYSVPMARFVDTFSRVLGDP---ALPHLFFVDGGALAVENALK
Mvan_1652|M.vanbaalenii_PYR-1 NKPSNSDVYSVPMARFVDTFARVLGDP---DLLHLFFVDGGALAVENALK
MSMEG_1764|M.smegmatis_MC2_155 NKPSNSDIYSVPMARFVDTFRRVLGDP---ALPHLFFVDGGALAVENALK
Mb3318c|M.bovis_AF2122/97 NKPSNSDVYSVAMARFVETFARVLGDP---ALPHLFFVEGGALAVENALK
Rv3290c|M.tuberculosis_H37Rv NKPSNSDVYSVAMARFVETFARVLGDP---ALPHLFFVEGGALAVENALK
MMAR_1243|M.marinum_M NKPSNADVYSVPMARFVQTFVRVLGDP---ALPHLFFVDGGALAVENALK
MUL_2644|M.ulcerans_Agy99 NKPSNADVYSVPMARFVQTFVRVLGDP---ALPHLFFVDGGALAVENALK
MAV_4262|M.avium_104 NKPSNSDVYSVPMARFVETFVRVLGDP---ALPHLFFVDGGALAVENALK
MAB_3646c|M.abscessus_ATCC_199 NKPSNSDIYTVEMARFVDTFARVLGDP---ALPHLFFVDGGALAVENALK
MLBr_01409|M.leprae_Br4923 N-----LYATEPSITLAEELVALLGAD---TQTRVFFCNSGTEANELAFK
TH_3246|M.thermoresistible__bu NIVHSLDMATAAKQEFLETFSELILKPRGLDYKVQFPGPTGANAVESALK
* : : : : :: * *: * * *:*
Mflv_4796|M.gilvum_PYR-GCK VAFDWKSRLNEAQGRSPDLGTKVLHLRGAFHGRSGYTMSLTNTDPNKVAR
Mvan_1652|M.vanbaalenii_PYR-1 VAFDWKSRLNEARGLDPALGTKVLHLKGAFHGRSGYTLSLTNTDPNKVAR
MSMEG_1764|M.smegmatis_MC2_155 VAFDWKSRHNEAHGIDPELGTKVLHLRGAFHGRSGYTLSLTNTDPVKVAR
Mb3318c|M.bovis_AF2122/97 AAFDWKSRHNQAHGIDPALGTQVLHLRGAFHGRSGYTLSLTNTKPTITAR
Rv3290c|M.tuberculosis_H37Rv AAFDWKSRHNQAHGIDPALGTQVLHLRGAFHGRSGYTLSLTNTKPTITAR
MMAR_1243|M.marinum_M VAFDWKSRHNQALGIDAGLGTKVLHLRGAFHGRSGYTLSLTNTKPVNVAR
MUL_2644|M.ulcerans_Agy99 VAFDWKSRHNQALGIDAGLGTKVLHLRGAFHGRSGYTLSLTNTKPVNVAR
MAV_4262|M.avium_104 VAFDWKNRHNERRGVDPALGTRVLHLRGAFHGRSGYTLSLTNTKPVTVAR
MAB_3646c|M.abscessus_ATCC_199 VAFDWKSRWNEAHGIDASLGTKVLHLREAFHGRSGYTMSLTNTDPNKVAR
MLBr_01409|M.leprae_Br4923 LSRLTG-------------RTKLVAAQAAFHGRTMGSLALTG-QPAKQAA
TH_3246|M.thermoresistible__bu LARKVTGR------------ESIVSFTNAFHGMTLGALSVTGNSMKRAGA
: :: **** : ::::*. . .
Mflv_4796|M.gilvum_PYR-GCK -FPKFDWPRIDAPSVRSGAN---IEALEAESLRQARAAFEAHPHDIACFI
Mvan_1652|M.vanbaalenii_PYR-1 -FPKFDWPRIDAPVCSAGMDNEAVDALEAESLRQARAAFEANPHDIACFI
MSMEG_1764|M.smegmatis_MC2_155 -FPKFDWPRIDAPYVRPGLDDDAMAALEAESLRQARAAFEAHPHDIACFI
Mb3318c|M.bovis_AF2122/97 -FPKFDWPRIDAPYMRPGLDEPAMAALEAEALRQARAAFETRPHDIACFV
Rv3290c|M.tuberculosis_H37Rv -FPKFDWPRIDAPYMRPGLDEPAMAALEAEALRQARAAFETRPHDIACFV
MMAR_1243|M.marinum_M -FPTFDWPRIDAPYIRP---DADMDAVEAESLAQARAAFEAHPHDIACFI
MUL_2644|M.ulcerans_Agy99 -FPTFDWPRIDAPYIRP---DADMDAVEAESLAQARAAFEAHPHDIACFI
MAV_4262|M.avium_104 -FPRFDWPRIDAPHLRCG---ADIDALEAESLRQARAAFAAHPHDIACFI
MAB_3646c|M.abscessus_ATCC_199 -FPKFDWPRIDAPYLRPG---ADIEALEASALAQARRAFAENPHDIACFI
MLBr_01409|M.leprae_Br4923 -FEPLPGHVTHVP------------------YGQVDALAAAVDNDTAAVF
TH_3246|M.thermoresistible__bu GVPLVHSTPMPYDNYFGG------VTEDFQWFEKVLDDEGSGLNRPAAVI
. . :. : *...
Mflv_4796|M.gilvum_PYR-GCK AEPIQGEGGDRHLRPEFFAAMRELCDEFDALLIFDEVQTGCGITGTAWAY
Mvan_1652|M.vanbaalenii_PYR-1 AEPIQGEGGDRHFRPQFFAAMRQLCDEFDSLLIFDEVQTGCGITGTPWAY
MSMEG_1764|M.smegmatis_MC2_155 AEPIQGEGGDRHFRPEFFAAMRELCDEFDALLIFDEVQTGCGITGTAWAY
Mb3318c|M.bovis_AF2122/97 AEPIQGEGGDRHFRPEFFAAMRELCDEFDALLIFDEVQTGCGLTGTAWAY
Rv3290c|M.tuberculosis_H37Rv AEPIQGEGGDRHFRPEFFAAMRELCDEFDALLIFDEVQTGCGLTGTAWAY
MMAR_1243|M.marinum_M AEPIQGEGGDRHFRPEFFAAMRRLCDEHDALLIFDEVQTGCAMTGTPWAY
MUL_2644|M.ulcerans_Agy99 AEPIQGEGGDRHFRPEFFAAMRRLCDEHDALLIFDEVQTGCAMTGTPWAY
MAV_4262|M.avium_104 AEPIQGEGGDRHFRPEFFAAMRRLCDEHDALLIFDEVQTGCGLTGTAWAY
MAB_3646c|M.abscessus_ATCC_199 AEPIQGEGGDHHFRPEFFHAMRALCHENDALFIFDEVQTGCGLTGTAWAF
MLBr_01409|M.leprae_Br4923 LEPIMGESGVIVPPEGYLAAARDITTRHGALLVIDEVQTGIGRTGAFFAH
TH_3246|M.thermoresistible__bu VETVQGEGGLNVARAEWLRALAELCHTRDILLIVDDVQMGCGRTGAFFSF
*.: **.* :: * : . *::.*:** * . **: ::.
Mflv_4796|M.gilvum_PYR-GCK QQLGVLPDVVAFGKKTQVCGVMAGTRVDEVPDNVFRTSSRINSTWGGNLV
Mvan_1652|M.vanbaalenii_PYR-1 QQLGVRPDVVAFGKKTQVCGVMAGGRVDEVPANVFHTSSRINSTWGGNLA
MSMEG_1764|M.smegmatis_MC2_155 QQLGVMPDVVSFGKKTQVCGVMAGRRVDEVADNVFAVSSRINSTWGGNLV
Mb3318c|M.bovis_AF2122/97 QQLDVAPDIVAFGKKTQVCGVMAGRRVDEVADNVFAVPSRLNSTWGGNLT
Rv3290c|M.tuberculosis_H37Rv QQLDVAPDIVAFGKKTQVCGVMAGRRVDEVADNVFAVPSRLNSTWGGNLT
MMAR_1243|M.marinum_M QQLGVKPDVVAFGKKTQVCGVMAGGRVDEIVDNVFAVSSRLNSTWGGNLT
MUL_2644|M.ulcerans_Agy99 QQLGVKPDVVAFGKKTQVCGVMAGGRVDEIVDNVFAVSSRLNSTWGGNLT
MAV_4262|M.avium_104 QQFGVQPDVVAFGKKTQVCGIMAGRRVDEVADNVFAVSSRLNSTWGGNLA
MAB_3646c|M.abscessus_ATCC_199 QQLGVIPDVVAFGKKTQVCGVMAGGRVDEVDDNVFAVSSRINSTWGGNLV
MLBr_01409|M.leprae_Br4923 QHDSITPDVVTLAKG-LGGGLPIGAFLATGPAAELLTLGLHGSTFGGNPV
TH_3246|M.thermoresistible__bu EEAGITPDIVTLSKSISGYGLPMALTLFRRELDVWAPGEHNGTFRGHNPA
:. .: **:*::.* *: . : .: * * .
Mflv_4796|M.gilvum_PYR-GCK DMVRARRILEVIERDGLFDNAAQRGRHLRDGLAGLAVEFPGLVRDVRGRG
Mvan_1652|M.vanbaalenii_PYR-1 DMVRARRILEVIEVDGLFDRAAESGRYLRDGLDGLAADFPVLVRDVRGRG
MSMEG_1764|M.smegmatis_MC2_155 DMVRSRRILEVIERDGLLDNARDMGAYLLDELRVLATRFPGVVVDPRGRG
Mb3318c|M.bovis_AF2122/97 DMVRARRILEVIEAEGLFERAVQHGKYLRARLDELAADFPAVVLDPRGRG
Rv3290c|M.tuberculosis_H37Rv DMVRARRILEVIEAEGLFERAVQHGKYLRARLDELAADFPAVVLDPRGRG
MMAR_1243|M.marinum_M DMVRARRILEVIEAEGLVDNAAEQGRYLRAQFDELAKDLPAVVLHPRGRG
MUL_2644|M.ulcerans_Agy99 DMVRSRRILEVIEAEGLVDNAAEQGRYLRAQFDELAKDLPAVVLHPRGRG
MAV_4262|M.avium_104 DMVRARRILEVIEADELFEHAARQGAYLLRGLHDLAREFPGLVLDVRGRG
MAB_3646c|M.abscessus_ATCC_199 DMVRSRRILEVVEAQRLFANAMRMGEYLLERLQTLAVRHDAVG-DVRGRG
MLBr_01409|M.leprae_Br4923 CTAAALAVLRVLATQGLVRRAEVLGDSMRIGIESLS---HPLIDQVRGRG
TH_3246|M.thermoresistible__bu FVTATAALKTYWQDDSFTAQTVRKGEFLRNELESIAARHEGVS--ARGRG
. : : : : .: * : : :: : ****
Mflv_4796|M.gilvum_PYR-GCK LMCAFSMPSARQRDELLARLWECG-VIMLGCGT--DSVRFRPALTVNDDE
Mvan_1652|M.vanbaalenii_PYR-1 LMCAFSMPSAAQRDALIAGLWDCG-VIMLGSGP--DSVRFRPALTVSTAE
MSMEG_1764|M.smegmatis_MC2_155 LMCAFSMPTPEDRDALIRKLWDRH-VIMLPSGA--DSVRFRPALPVTRAE
Mb3318c|M.bovis_AF2122/97 LMCAFSLPTTADRDELIRQLWQRA-VIVLPAGA--DTVRFRPPLTVSTAE
Rv3290c|M.tuberculosis_H37Rv LMCAFSLPTTADRDELIRQLWQRA-VIVLPAGA--DTVRFRPPLTVSTAE
MMAR_1243|M.marinum_M LMCAFDLPTTADRDELIQRLWQRA-VIALPAGK--VSVRFRPALTVGRDE
MUL_2644|M.ulcerans_Agy99 LMCAFDLPTTADRDELIQRLWQRA-VIALPAGK--VSVRFRPALTVGRDE
MAV_4262|M.avium_104 LMCAFSLPTTADRDELIGRLWRGG-VIVLPTGD--DGVRFRPALTVSRGE
MAB_3646c|M.abscessus_ATCC_199 LMCAFSLPTAEERDHLVQRLWADERVILLPSGE--NSVRFRPPLIVSAEE
MLBr_01409|M.leprae_Br4923 LLLGIVLTAPRAKD--IEKAARDAGFLVNATAP--EVIRLAPPLIITESQ
TH_3246|M.thermoresistible__bu MAQGLKFEQEDLAGAVCRAAFDRG-LLMETSGPSDEVVKLLPPLTMSQEE
: .: : . .: . ::: *.* : :
Mflv_4796|M.gilvum_PYR-GCK IDAALTAVAAVLRTMAVPQAG--
Mvan_1652|M.vanbaalenii_PYR-1 LDAALDAVRAVLRTM--------
MSMEG_1764|M.smegmatis_MC2_155 IDACLDAVRAVLSER--------
Mb3318c|M.bovis_AF2122/97 IDAAIAAVRSALPVVT-------
Rv3290c|M.tuberculosis_H37Rv IDAAIAAVRSALPVVT-------
MMAR_1243|M.marinum_M IDLAIAAVRSALSAMT-------
MUL_2644|M.ulcerans_Agy99 IDLAIAAVRSALSAMT-------
MAV_4262|M.avium_104 IDAAIGAVRDALPTLG-------
MAB_3646c|M.abscessus_ATCC_199 IDAAVAAVSRVLALR--------
MLBr_01409|M.leprae_Br4923 IDSFITALPGILDASIAELGKKA
TH_3246|M.thermoresistible__bu LEAGLGILADAVAATVD------
:: : : :