For questions or suggestions e-mail us at: ioerger@cs.tamu.edu
TALIFPGFQAGPTHGDQATRPDPVTPDRVHDVLRRSILADGMDLVLDLERSHGAHLVDARDGTDYLDMFT FFASSALGMNHPMLAEDDEFRAELATAAINKPSNSDIYTVEMARFVDTFARVLGDPALPHLFFVDGGALA VENALKVAFDWKSRWNEAHGIDASLGTKVLHLREAFHGRSGYTMSLTNTDPNKVARFPKFDWPRIDAPYL RPGADIEALEASALAQARRAFAENPHDIACFIAEPIQGEGGDHHFRPEFFHAMRALCHENDALFIFDEVQ TGCGLTGTAWAFQQLGVIPDVVAFGKKTQVCGVMAGGRVDEVDDNVFAVSSRINSTWGGNLVDMVRSRRI LEVVEAQRLFANAMRMGEYLLERLQTLAVRHDAVGDVRGRGLMCAFSLPTAEERDHLVQRLWADERVILL PSGENSVRFRPPLIVSAEEIDAAVAAVSRVLALR*
Operon Prediction Model: Genebank
Paralogs
species | id | gene | e-value | identity (len) | annotation |
M. abscessus ATCC 19977 | MAB_3646c | - | - | 100% (455) | L-lysine aminotransferase |
M. abscessus ATCC 19977 | MAB_4207 | - | 9e-32 | 31.65% (417) | 4-aminobutyrate aminotransferase |
M. abscessus ATCC 19977 | MAB_4417c | - | 4e-30 | 28.74% (421) | aminotransferase |
Closest Orthologs (e-value cutoff: 1e-4)
species | id | gene | e-value | identity (len) | annotation |
M. bovis AF2122 / 97 | Mb3318c | lat | 0.0 | 73.44% (433) | L-lysine aminotransferase |
M. gilvum PYR-GCK | Mflv_4796 | - | 0.0 | 75.46% (436) | L-lysine aminotransferase |
M. tuberculosis H37Rv | Rv3290c | lat | 0.0 | 73.44% (433) | L-lysine aminotransferase |
M. leprae Br4923 | MLBr_00485 | gabT | 1e-27 | 27.23% (459) | 4-aminobutyrate aminotransferase |
M. marinum M | MMAR_1243 | lat | 1e-179 | 73.26% (430) | L-lysine-epsilon aminotransferase Lat |
M. avium 104 | MAV_4262 | - | 0.0 | 75.64% (427) | L-lysine aminotransferase |
M. smegmatis MC2 155 | MSMEG_1764 | - | 0.0 | 74.78% (448) | L-lysine aminotransferase |
M. thermoresistible (build 8) | TH_3529 | - | 1e-26 | 29.17% (408) | PUTATIVE aminotransferase |
M. ulcerans Agy99 | MUL_2644 | lat | 1e-180 | 73.26% (430) | L-lysine aminotransferase |
M. vanbaalenii PYR-1 | Mvan_1652 | - | 0.0 | 74.42% (434) | L-lysine aminotransferase |
CLUSTAL 2.0.9 multiple sequence alignment Mflv_4796|M.gilvum_PYR-GCK ---------MTAVLSRAD--RTAVIVPADVRTVLSRSILADGLDLVLDLE Mvan_1652|M.vanbaalenii_PYR-1 ------MPLHASVRPEADA-ETDRLGPDDVHHVLARSILADGLDLVLDID MSMEG_1764|M.smegmatis_MC2_155 ----MTALLNTPVSGSSSPGASPELAPELVRETLARSILADGFDFVLDLE Mb3318c|M.bovis_AF2122/97 ---------MAAVVKSVAL-AGRPTTPDRVHEVLGRSMLVDGLDIVLDLT Rv3290c|M.tuberculosis_H37Rv ---------MAAVVKSVAL-AGRPTTPDRVHEVLGRSMLVDGLDIVLDLT MMAR_1243|M.marinum_M ---------MTAAVRSTVP-ACQQIEADDVQEVLGRSMLVDGFDLVLDLS MUL_2644|M.ulcerans_Agy99 ---------MTAAVRSTVP-ACQQIEADDIQEVLGRSMLVDGFDLVLDLS MAV_4262|M.avium_104 ---------MTAALERLAR-ARSCTGPDRVHEVLSRSILTDGFDFVLDLD MAB_3646c|M.abscessus_ATCC_199 MTALIFPGFQAGPTHGDQATRPDPVTPDRVHDVLRRSILADGMDLVLDLE MLBr_00485|M.leprae_Br4923 -------MTSVEQSRQLVTEIPGPVSLELAKRLNAAVPRGVGVTLPVFVT TH_3529|M.thermoresistible__bu -------VSGSKGRHTLLDRWQGVMMNNYG-------------TPPLALV : : Mflv_4796|M.gilvum_PYR-GCK RSHGSYLVDARTGRGYLDMFTFFASSALGMNHPALADDPDFRAELAAAAV Mvan_1652|M.vanbaalenii_PYR-1 RSHGSHLVDARTGRSYLDMFTFFASSALGMNHPGLAGDPEFRAELAAAAL MSMEG_1764|M.smegmatis_MC2_155 ESRGSHLVDARTGERFLDMFTFFASSALGMNHSALADDPEFRAELAQAAL Mb3318c|M.bovis_AF2122/97 RSGGSYLVDAITGRRYLDMFTFVASSALGMNPPALVDDREFHAELMQAAL Rv3290c|M.tuberculosis_H37Rv RSGGSYLVDAITGRRYLDMFTFVASSALGMNPPALVDDREFHAELMQAAL MMAR_1243|M.marinum_M QSAGSYLVDARTGRRYLDMFTFFASSALGMNHPGLAEDEQFRAELLEAAL MUL_2644|M.ulcerans_Agy99 QSAGSYLVDARTGRRYLDMFTFFASSALGMNHPGLAEDEQFRAELLEAAL MAV_4262|M.avium_104 RSRGSVLYDARDGRRYLDMFTFFASSALGMNHPALARDAEFRAELTAAAL MAB_3646c|M.abscessus_ATCC_199 RSHGAHLVDARDGTDYLDMFTFFASSALGMNHPMLAEDDEFRAELATAAI MLBr_00485|M.leprae_Br4923 RAAGGVIEDVD-GNRLIDLGSGIAVTTIGNSSPRVVDA----VRAQVADF TH_3529|M.thermoresistible__bu SGDGAVVTDAD-GKSYLDLLGGIAVNILGHRHPAVIEA----VTRQLNTL . *. : *. * :*: .* . :* . : . . Mflv_4796|M.gilvum_PYR-GCK NKPSNSDVYSVPMARFVDTFSRVLGDPALPHLFFVDGGALAVENALKVAF Mvan_1652|M.vanbaalenii_PYR-1 NKPSNSDVYSVPMARFVDTFARVLGDPDLLHLFFVDGGALAVENALKVAF MSMEG_1764|M.smegmatis_MC2_155 NKPSNSDIYSVPMARFVDTFRRVLGDPALPHLFFVDGGALAVENALKVAF Mb3318c|M.bovis_AF2122/97 NKPSNSDVYSVAMARFVETFARVLGDPALPHLFFVEGGALAVENALKAAF Rv3290c|M.tuberculosis_H37Rv NKPSNSDVYSVAMARFVETFARVLGDPALPHLFFVEGGALAVENALKAAF MMAR_1243|M.marinum_M NKPSNADVYSVPMARFVQTFVRVLGDPALPHLFFVDGGALAVENALKVAF MUL_2644|M.ulcerans_Agy99 NKPSNADVYSVPMARFVQTFVRVLGDPALPHLFFVDGGALAVENALKVAF MAV_4262|M.avium_104 NKPSNSDVYSVPMARFVETFVRVLGDPALPHLFFVDGGALAVENALKVAF MAB_3646c|M.abscessus_ATCC_199 NKPSNSDIYTVEMARFVDTFARVLGDPALPHLFFVDGGALAVENALKVAF MLBr_00485|M.leprae_Br4923 THTCFIITPYEEYVAVTEQLNRITPGSGEKRSVLFNSGAEAVENSIKVAR TH_3529|M.thermoresistible__bu GHTSNLYATEPGVALAEALVGHLG---APARVFFCNSGAEANEVAFKISR :.. . . :: : .: :.** * * ::* : Mflv_4796|M.gilvum_PYR-GCK DWKSRLNEAQGRSPDLGTKVLHLRGAFHGRSGYTMSLTNTDPNKVARFPK Mvan_1652|M.vanbaalenii_PYR-1 DWKSRLNEARGLDPALGTKVLHLKGAFHGRSGYTLSLTNTDPNKVARFPK MSMEG_1764|M.smegmatis_MC2_155 DWKSRHNEAHGIDPELGTKVLHLRGAFHGRSGYTLSLTNTDPVKVARFPK Mb3318c|M.bovis_AF2122/97 DWKSRHNQAHGIDPALGTQVLHLRGAFHGRSGYTLSLTNTKPTITARFPK Rv3290c|M.tuberculosis_H37Rv DWKSRHNQAHGIDPALGTQVLHLRGAFHGRSGYTLSLTNTKPTITARFPK MMAR_1243|M.marinum_M DWKSRHNQALGIDAGLGTKVLHLRGAFHGRSGYTLSLTNTKPVNVARFPT MUL_2644|M.ulcerans_Agy99 DWKSRHNQALGIDAGLGTKVLHLRGAFHGRSGYTLSLTNTKPVNVARFPT MAV_4262|M.avium_104 DWKNRHNERRGVDPALGTRVLHLRGAFHGRSGYTLSLTNTKPVTVARFPR MAB_3646c|M.abscessus_ATCC_199 DWKSRWNEAHGIDASLGTKVLHLREAFHGRSGYTMSLTNTDPNKVARFPK MLBr_00485|M.leprae_Br4923 SYTRKP------------AVVAFDHAYHGRTNLTMALTAKSMPYKSGFGP TH_3529|M.thermoresistible__bu -LTGRT------------KVVAAEGGFHGRTMGALALTGQPSKREP-FEP . : *: .:***: :::** . * Mflv_4796|M.gilvum_PYR-GCK FDWPRIDAPSVRSGAN--------IEALEAESLRQARAAFEAHPHDIACF Mvan_1652|M.vanbaalenii_PYR-1 FDWPRIDAPVCSAGMD-----NEAVDALEAESLRQARAAFEANPHDIACF MSMEG_1764|M.smegmatis_MC2_155 FDWPRIDAPYVRPGLD-----DDAMAALEAESLRQARAAFEAHPHDIACF Mb3318c|M.bovis_AF2122/97 FDWPRIDAPYMRPGLD-----EPAMAALEAEALRQARAAFETRPHDIACF Rv3290c|M.tuberculosis_H37Rv FDWPRIDAPYMRPGLD-----EPAMAALEAEALRQARAAFETRPHDIACF MMAR_1243|M.marinum_M FDWPRIDAPYIRP--------DADMDAVEAESLAQARAAFEAHPHDIACF MUL_2644|M.ulcerans_Agy99 FDWPRIDAPYIRP--------DADMDAVEAESLAQARAAFEAHPHDIACF MAV_4262|M.avium_104 FDWPRIDAPHLRCG--------ADIDALEAESLRQARAAFAAHPHDIACF MAB_3646c|M.abscessus_ATCC_199 FDWPRIDAPYLRPG--------ADIEALEASALAQARRAFAENPHDIACF MLBr_00485|M.leprae_Br4923 FAPEIYRAPLSYPYRDGLLNKDLATDGKLAGARAINVIEKQVGADDLAAV TH_3529|M.thermoresistible__bu LPGDVIHVPYGDAG-----------------------ALERAVDDTTAAV : .* . *.. Mflv_4796|M.gilvum_PYR-GCK IAEPIQGEGGDRHLRPEFFAAMRELCDEFDALLIFDEVQTGCGITGTAWA Mvan_1652|M.vanbaalenii_PYR-1 IAEPIQGEGGDRHFRPQFFAAMRQLCDEFDSLLIFDEVQTGCGITGTPWA MSMEG_1764|M.smegmatis_MC2_155 IAEPIQGEGGDRHFRPEFFAAMRELCDEFDALLIFDEVQTGCGITGTAWA Mb3318c|M.bovis_AF2122/97 VAEPIQGEGGDRHFRPEFFAAMRELCDEFDALLIFDEVQTGCGLTGTAWA Rv3290c|M.tuberculosis_H37Rv VAEPIQGEGGDRHFRPEFFAAMRELCDEFDALLIFDEVQTGCGLTGTAWA MMAR_1243|M.marinum_M IAEPIQGEGGDRHFRPEFFAAMRRLCDEHDALLIFDEVQTGCAMTGTPWA MUL_2644|M.ulcerans_Agy99 IAEPIQGEGGDRHFRPEFFAAMRRLCDEHDALLIFDEVQTGCAMTGTPWA MAV_4262|M.avium_104 IAEPIQGEGGDRHFRPEFFAAMRRLCDEHDALLIFDEVQTGCGLTGTAWA MAB_3646c|M.abscessus_ATCC_199 IAEPIQGEGGDHHFRPEFFHAMRALCHENDALFIFDEVQTGCGLTGTAWA MLBr_00485|M.leprae_Br4923 IIEPIQGEGGFIVPAEGFLATLLDWCRKNNVMFIADEVQTGFARTGAMFA TH_3529|M.thermoresistible__bu FLEPIMGEGGVVVPPAGYLAAAREVTARHGALLVLDEVQTGIGRTGTFFA . *** **** :: : . . ::: ****** . **: :* Mflv_4796|M.gilvum_PYR-GCK YQQLGVLPDVVAFGKKTQVCGVMAGTRVDEVPDNVFRTSSRINSTWGGNL Mvan_1652|M.vanbaalenii_PYR-1 YQQLGVRPDVVAFGKKTQVCGVMAGGRVDEVPANVFHTSSRINSTWGGNL MSMEG_1764|M.smegmatis_MC2_155 YQQLGVMPDVVSFGKKTQVCGVMAGRRVDEVADNVFAVSSRINSTWGGNL Mb3318c|M.bovis_AF2122/97 YQQLDVAPDIVAFGKKTQVCGVMAGRRVDEVADNVFAVPSRLNSTWGGNL Rv3290c|M.tuberculosis_H37Rv YQQLDVAPDIVAFGKKTQVCGVMAGRRVDEVADNVFAVPSRLNSTWGGNL MMAR_1243|M.marinum_M YQQLGVKPDVVAFGKKTQVCGVMAGGRVDEIVDNVFAVSSRLNSTWGGNL MUL_2644|M.ulcerans_Agy99 YQQLGVKPDVVAFGKKTQVCGVMAGGRVDEIVDNVFAVSSRLNSTWGGNL MAV_4262|M.avium_104 YQQFGVQPDVVAFGKKTQVCGIMAGRRVDEVADNVFAVSSRLNSTWGGNL MAB_3646c|M.abscessus_ATCC_199 FQQLGVIPDVVAFGKKTQVCGVMAGGRVDEVDDNVFAVSSRINSTWGGNL MLBr_00485|M.leprae_Br4923 CEHDGIVPDLICTAKG-IADGLPLAAVTGRAEIMNAPHVSGLGGTFGGNP TH_3529|M.thermoresistible__bu HQHDGITPDVVTLAKG-LGGGLPIGACLAVGPAGDLLTPGMHGSTFGGNP :: .: **:: .* *: . . ..*:*** Mflv_4796|M.gilvum_PYR-GCK VDMVRARRILEVIERDGLFDNAAQRGRHLRDGLAGLAVEFPGLVRDVRGR Mvan_1652|M.vanbaalenii_PYR-1 ADMVRARRILEVIEVDGLFDRAAESGRYLRDGLDGLAADFPVLVRDVRGR MSMEG_1764|M.smegmatis_MC2_155 VDMVRSRRILEVIERDGLLDNARDMGAYLLDELRVLATRFPGVVVDPRGR Mb3318c|M.bovis_AF2122/97 TDMVRARRILEVIEAEGLFERAVQHGKYLRARLDELAADFPAVVLDPRGR Rv3290c|M.tuberculosis_H37Rv TDMVRARRILEVIEAEGLFERAVQHGKYLRARLDELAADFPAVVLDPRGR MMAR_1243|M.marinum_M TDMVRARRILEVIEAEGLVDNAAEQGRYLRAQFDELAKDLPAVVLHPRGR MUL_2644|M.ulcerans_Agy99 TDMVRSRRILEVIEAEGLVDNAAEQGRYLRAQFDELAKDLPAVVLHPRGR MAV_4262|M.avium_104 ADMVRARRILEVIEADELFEHAARQGAYLLRGLHDLAREFPGLVLDVRGR MAB_3646c|M.abscessus_ATCC_199 VDMVRSRRILEVVEAQRLFANAMRMGEYLLERLQTLAVRHDAVG-DVRGR MLBr_00485|M.leprae_Br4923 VACAAALATITTIENDGLIQRAQQIERLITDRLLRLQDAD-DRIGDVRGR TH_3529|M.thermoresistible__bu VCTAAAVAVLGALAEGDLINRADVLGKKLSHGIEELRHP---LVDHVRGR . . : : .: *. .* : : * . *** Mflv_4796|M.gilvum_PYR-GCK GLMCAFSMPSARQ--------RDELLARLWECG-VIMLGCGTDSVRFRPA Mvan_1652|M.vanbaalenii_PYR-1 GLMCAFSMPSAAQ--------RDALIAGLWDCG-VIMLGSGPDSVRFRPA MSMEG_1764|M.smegmatis_MC2_155 GLMCAFSMPTPED--------RDALIRKLWDRH-VIMLPSGADSVRFRPA Mb3318c|M.bovis_AF2122/97 GLMCAFSLPTTAD--------RDELIRQLWQRA-VIVLPAGADTVRFRPP Rv3290c|M.tuberculosis_H37Rv GLMCAFSLPTTAD--------RDELIRQLWQRA-VIVLPAGADTVRFRPP MMAR_1243|M.marinum_M GLMCAFDLPTTAD--------RDELIQRLWQRA-VIALPAGKVSVRFRPA MUL_2644|M.ulcerans_Agy99 GLMCAFDLPTTAD--------RDELIQRLWQRA-VIALPAGKVSVRFRPA MAV_4262|M.avium_104 GLMCAFSLPTTAD--------RDELIGRLWRGG-VIVLPTGDDGVRFRPA MAB_3646c|M.abscessus_ATCC_199 GLMCAFSLPTAEE--------RDHLVQRLWADERVILLPSGENSVRFRPP MLBr_00485|M.leprae_Br4923 GAMIAVELVKSGTAEPDPELTEKVATAAHATGVIILTCGMFGNIIRLLPP TH_3529|M.thermoresistible__bu GLLCGVVLNAP----------QAKAAEAAARDAGFLVNAAAPEVIRLAPP * : .. : . . .: :*: *. Mflv_4796|M.gilvum_PYR-GCK LTVNDDEIDAALTAVAAVLRTMAVPQAG Mvan_1652|M.vanbaalenii_PYR-1 LTVSTAELDAALDAVRAVLRTM------ MSMEG_1764|M.smegmatis_MC2_155 LPVTRAEIDACLDAVRAVLSER------ Mb3318c|M.bovis_AF2122/97 LTVSTAEIDAAIAAVRSALPVVT----- Rv3290c|M.tuberculosis_H37Rv LTVSTAEIDAAIAAVRSALPVVT----- MMAR_1243|M.marinum_M LTVGRDEIDLAIAAVRSALSAMT----- MUL_2644|M.ulcerans_Agy99 LTVGRDEIDLAIAAVRSALSAMT----- MAV_4262|M.avium_104 LTVSRGEIDAAIGAVRDALPTLG----- MAB_3646c|M.abscessus_ATCC_199 LIVSAEEIDAAVAAVSRVLALR------ MLBr_00485|M.leprae_Br4923 LTISDELLAEGLDILSRILGDF------ TH_3529|M.thermoresistible__bu LIITETQIDEFLAALPGVLDTAKEAS-- * : : : : *