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M. abscessus ATCC 19977 MAB_3646c (-)

annotation: L-lysine aminotransferase
coordinates: 3694910 - 3696277
length: 455

TALIFPGFQAGPTHGDQATRPDPVTPDRVHDVLRRSILADGMDLVLDLERSHGAHLVDARDGTDYLDMFT
FFASSALGMNHPMLAEDDEFRAELATAAINKPSNSDIYTVEMARFVDTFARVLGDPALPHLFFVDGGALA
VENALKVAFDWKSRWNEAHGIDASLGTKVLHLREAFHGRSGYTMSLTNTDPNKVARFPKFDWPRIDAPYL
RPGADIEALEASALAQARRAFAENPHDIACFIAEPIQGEGGDHHFRPEFFHAMRALCHENDALFIFDEVQ
TGCGLTGTAWAFQQLGVIPDVVAFGKKTQVCGVMAGGRVDEVDDNVFAVSSRINSTWGGNLVDMVRSRRI
LEVVEAQRLFANAMRMGEYLLERLQTLAVRHDAVGDVRGRGLMCAFSLPTAEERDHLVQRLWADERVILL
PSGENSVRFRPPLIVSAEEIDAAVAAVSRVLALR*
Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. abscessus ATCC 19977MAB_3646c--100% (455)L-lysine aminotransferase
M. abscessus ATCC 19977MAB_4207-9e-3231.65% (417) 4-aminobutyrate aminotransferase
M. abscessus ATCC 19977MAB_4417c-4e-3028.74% (421) aminotransferase

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97Mb3318clat0.073.44% (433) L-lysine aminotransferase
M. gilvum PYR-GCKMflv_4796-0.075.46% (436) L-lysine aminotransferase
M. tuberculosis H37RvRv3290clat0.073.44% (433) L-lysine aminotransferase
M. leprae Br4923MLBr_00485gabT1e-2727.23% (459) 4-aminobutyrate aminotransferase
M. marinum MMMAR_1243lat1e-17973.26% (430) L-lysine-epsilon aminotransferase Lat
M. avium 104MAV_4262-0.075.64% (427) L-lysine aminotransferase
M. smegmatis MC2 155MSMEG_1764-0.074.78% (448) L-lysine aminotransferase
M. thermoresistible (build 8)TH_3529-1e-2629.17% (408) PUTATIVE aminotransferase
M. ulcerans Agy99MUL_2644lat1e-18073.26% (430) L-lysine aminotransferase
M. vanbaalenii PYR-1Mvan_1652-0.074.42% (434) L-lysine aminotransferase

CLUSTAL 2.0.9 multiple sequence alignment


Mflv_4796|M.gilvum_PYR-GCK          ---------MTAVLSRAD--RTAVIVPADVRTVLSRSILADGLDLVLDLE
Mvan_1652|M.vanbaalenii_PYR-1       ------MPLHASVRPEADA-ETDRLGPDDVHHVLARSILADGLDLVLDID
MSMEG_1764|M.smegmatis_MC2_155      ----MTALLNTPVSGSSSPGASPELAPELVRETLARSILADGFDFVLDLE
Mb3318c|M.bovis_AF2122/97           ---------MAAVVKSVAL-AGRPTTPDRVHEVLGRSMLVDGLDIVLDLT
Rv3290c|M.tuberculosis_H37Rv        ---------MAAVVKSVAL-AGRPTTPDRVHEVLGRSMLVDGLDIVLDLT
MMAR_1243|M.marinum_M               ---------MTAAVRSTVP-ACQQIEADDVQEVLGRSMLVDGFDLVLDLS
MUL_2644|M.ulcerans_Agy99           ---------MTAAVRSTVP-ACQQIEADDIQEVLGRSMLVDGFDLVLDLS
MAV_4262|M.avium_104                ---------MTAALERLAR-ARSCTGPDRVHEVLSRSILTDGFDFVLDLD
MAB_3646c|M.abscessus_ATCC_199      MTALIFPGFQAGPTHGDQATRPDPVTPDRVHDVLRRSILADGMDLVLDLE
MLBr_00485|M.leprae_Br4923          -------MTSVEQSRQLVTEIPGPVSLELAKRLNAAVPRGVGVTLPVFVT
TH_3529|M.thermoresistible__bu      -------VSGSKGRHTLLDRWQGVMMNNYG-------------TPPLALV
                                                                                  : : 

Mflv_4796|M.gilvum_PYR-GCK          RSHGSYLVDARTGRGYLDMFTFFASSALGMNHPALADDPDFRAELAAAAV
Mvan_1652|M.vanbaalenii_PYR-1       RSHGSHLVDARTGRSYLDMFTFFASSALGMNHPGLAGDPEFRAELAAAAL
MSMEG_1764|M.smegmatis_MC2_155      ESRGSHLVDARTGERFLDMFTFFASSALGMNHSALADDPEFRAELAQAAL
Mb3318c|M.bovis_AF2122/97           RSGGSYLVDAITGRRYLDMFTFVASSALGMNPPALVDDREFHAELMQAAL
Rv3290c|M.tuberculosis_H37Rv        RSGGSYLVDAITGRRYLDMFTFVASSALGMNPPALVDDREFHAELMQAAL
MMAR_1243|M.marinum_M               QSAGSYLVDARTGRRYLDMFTFFASSALGMNHPGLAEDEQFRAELLEAAL
MUL_2644|M.ulcerans_Agy99           QSAGSYLVDARTGRRYLDMFTFFASSALGMNHPGLAEDEQFRAELLEAAL
MAV_4262|M.avium_104                RSRGSVLYDARDGRRYLDMFTFFASSALGMNHPALARDAEFRAELTAAAL
MAB_3646c|M.abscessus_ATCC_199      RSHGAHLVDARDGTDYLDMFTFFASSALGMNHPMLAEDDEFRAELATAAI
MLBr_00485|M.leprae_Br4923          RAAGGVIEDVD-GNRLIDLGSGIAVTTIGNSSPRVVDA----VRAQVADF
TH_3529|M.thermoresistible__bu      SGDGAVVTDAD-GKSYLDLLGGIAVNILGHRHPAVIEA----VTRQLNTL
                                     . *. : *.  *   :*:   .* . :*   . :       .      .

Mflv_4796|M.gilvum_PYR-GCK          NKPSNSDVYSVPMARFVDTFSRVLGDPALPHLFFVDGGALAVENALKVAF
Mvan_1652|M.vanbaalenii_PYR-1       NKPSNSDVYSVPMARFVDTFARVLGDPDLLHLFFVDGGALAVENALKVAF
MSMEG_1764|M.smegmatis_MC2_155      NKPSNSDIYSVPMARFVDTFRRVLGDPALPHLFFVDGGALAVENALKVAF
Mb3318c|M.bovis_AF2122/97           NKPSNSDVYSVAMARFVETFARVLGDPALPHLFFVEGGALAVENALKAAF
Rv3290c|M.tuberculosis_H37Rv        NKPSNSDVYSVAMARFVETFARVLGDPALPHLFFVEGGALAVENALKAAF
MMAR_1243|M.marinum_M               NKPSNADVYSVPMARFVQTFVRVLGDPALPHLFFVDGGALAVENALKVAF
MUL_2644|M.ulcerans_Agy99           NKPSNADVYSVPMARFVQTFVRVLGDPALPHLFFVDGGALAVENALKVAF
MAV_4262|M.avium_104                NKPSNSDVYSVPMARFVETFVRVLGDPALPHLFFVDGGALAVENALKVAF
MAB_3646c|M.abscessus_ATCC_199      NKPSNSDIYTVEMARFVDTFARVLGDPALPHLFFVDGGALAVENALKVAF
MLBr_00485|M.leprae_Br4923          THTCFIITPYEEYVAVTEQLNRITPGSGEKRSVLFNSGAEAVENSIKVAR
TH_3529|M.thermoresistible__bu      GHTSNLYATEPGVALAEALVGHLG---APARVFFCNSGAEANEVAFKISR
                                     :..         .     . ::       : .: :.** * * ::* : 

Mflv_4796|M.gilvum_PYR-GCK          DWKSRLNEAQGRSPDLGTKVLHLRGAFHGRSGYTMSLTNTDPNKVARFPK
Mvan_1652|M.vanbaalenii_PYR-1       DWKSRLNEARGLDPALGTKVLHLKGAFHGRSGYTLSLTNTDPNKVARFPK
MSMEG_1764|M.smegmatis_MC2_155      DWKSRHNEAHGIDPELGTKVLHLRGAFHGRSGYTLSLTNTDPVKVARFPK
Mb3318c|M.bovis_AF2122/97           DWKSRHNQAHGIDPALGTQVLHLRGAFHGRSGYTLSLTNTKPTITARFPK
Rv3290c|M.tuberculosis_H37Rv        DWKSRHNQAHGIDPALGTQVLHLRGAFHGRSGYTLSLTNTKPTITARFPK
MMAR_1243|M.marinum_M               DWKSRHNQALGIDAGLGTKVLHLRGAFHGRSGYTLSLTNTKPVNVARFPT
MUL_2644|M.ulcerans_Agy99           DWKSRHNQALGIDAGLGTKVLHLRGAFHGRSGYTLSLTNTKPVNVARFPT
MAV_4262|M.avium_104                DWKNRHNERRGVDPALGTRVLHLRGAFHGRSGYTLSLTNTKPVTVARFPR
MAB_3646c|M.abscessus_ATCC_199      DWKSRWNEAHGIDASLGTKVLHLREAFHGRSGYTMSLTNTDPNKVARFPK
MLBr_00485|M.leprae_Br4923          SYTRKP------------AVVAFDHAYHGRTNLTMALTAKSMPYKSGFGP
TH_3529|M.thermoresistible__bu      -LTGRT------------KVVAAEGGFHGRTMGALALTGQPSKREP-FEP
                                      . :              *:    .:***:  :::**       . *  

Mflv_4796|M.gilvum_PYR-GCK          FDWPRIDAPSVRSGAN--------IEALEAESLRQARAAFEAHPHDIACF
Mvan_1652|M.vanbaalenii_PYR-1       FDWPRIDAPVCSAGMD-----NEAVDALEAESLRQARAAFEANPHDIACF
MSMEG_1764|M.smegmatis_MC2_155      FDWPRIDAPYVRPGLD-----DDAMAALEAESLRQARAAFEAHPHDIACF
Mb3318c|M.bovis_AF2122/97           FDWPRIDAPYMRPGLD-----EPAMAALEAEALRQARAAFETRPHDIACF
Rv3290c|M.tuberculosis_H37Rv        FDWPRIDAPYMRPGLD-----EPAMAALEAEALRQARAAFETRPHDIACF
MMAR_1243|M.marinum_M               FDWPRIDAPYIRP--------DADMDAVEAESLAQARAAFEAHPHDIACF
MUL_2644|M.ulcerans_Agy99           FDWPRIDAPYIRP--------DADMDAVEAESLAQARAAFEAHPHDIACF
MAV_4262|M.avium_104                FDWPRIDAPHLRCG--------ADIDALEAESLRQARAAFAAHPHDIACF
MAB_3646c|M.abscessus_ATCC_199      FDWPRIDAPYLRPG--------ADIEALEASALAQARRAFAENPHDIACF
MLBr_00485|M.leprae_Br4923          FAPEIYRAPLSYPYRDGLLNKDLATDGKLAGARAINVIEKQVGADDLAAV
TH_3529|M.thermoresistible__bu      LPGDVIHVPYGDAG-----------------------ALERAVDDTTAAV
                                    :      .*                                   .  *..

Mflv_4796|M.gilvum_PYR-GCK          IAEPIQGEGGDRHLRPEFFAAMRELCDEFDALLIFDEVQTGCGITGTAWA
Mvan_1652|M.vanbaalenii_PYR-1       IAEPIQGEGGDRHFRPQFFAAMRQLCDEFDSLLIFDEVQTGCGITGTPWA
MSMEG_1764|M.smegmatis_MC2_155      IAEPIQGEGGDRHFRPEFFAAMRELCDEFDALLIFDEVQTGCGITGTAWA
Mb3318c|M.bovis_AF2122/97           VAEPIQGEGGDRHFRPEFFAAMRELCDEFDALLIFDEVQTGCGLTGTAWA
Rv3290c|M.tuberculosis_H37Rv        VAEPIQGEGGDRHFRPEFFAAMRELCDEFDALLIFDEVQTGCGLTGTAWA
MMAR_1243|M.marinum_M               IAEPIQGEGGDRHFRPEFFAAMRRLCDEHDALLIFDEVQTGCAMTGTPWA
MUL_2644|M.ulcerans_Agy99           IAEPIQGEGGDRHFRPEFFAAMRRLCDEHDALLIFDEVQTGCAMTGTPWA
MAV_4262|M.avium_104                IAEPIQGEGGDRHFRPEFFAAMRRLCDEHDALLIFDEVQTGCGLTGTAWA
MAB_3646c|M.abscessus_ATCC_199      IAEPIQGEGGDHHFRPEFFHAMRALCHENDALFIFDEVQTGCGLTGTAWA
MLBr_00485|M.leprae_Br4923          IIEPIQGEGGFIVPAEGFLATLLDWCRKNNVMFIADEVQTGFARTGAMFA
TH_3529|M.thermoresistible__bu      FLEPIMGEGGVVVPPAGYLAAAREVTARHGALLVLDEVQTGIGRTGTFFA
                                    . *** ****       :: :      . . ::: ****** . **: :*

Mflv_4796|M.gilvum_PYR-GCK          YQQLGVLPDVVAFGKKTQVCGVMAGTRVDEVPDNVFRTSSRINSTWGGNL
Mvan_1652|M.vanbaalenii_PYR-1       YQQLGVRPDVVAFGKKTQVCGVMAGGRVDEVPANVFHTSSRINSTWGGNL
MSMEG_1764|M.smegmatis_MC2_155      YQQLGVMPDVVSFGKKTQVCGVMAGRRVDEVADNVFAVSSRINSTWGGNL
Mb3318c|M.bovis_AF2122/97           YQQLDVAPDIVAFGKKTQVCGVMAGRRVDEVADNVFAVPSRLNSTWGGNL
Rv3290c|M.tuberculosis_H37Rv        YQQLDVAPDIVAFGKKTQVCGVMAGRRVDEVADNVFAVPSRLNSTWGGNL
MMAR_1243|M.marinum_M               YQQLGVKPDVVAFGKKTQVCGVMAGGRVDEIVDNVFAVSSRLNSTWGGNL
MUL_2644|M.ulcerans_Agy99           YQQLGVKPDVVAFGKKTQVCGVMAGGRVDEIVDNVFAVSSRLNSTWGGNL
MAV_4262|M.avium_104                YQQFGVQPDVVAFGKKTQVCGIMAGRRVDEVADNVFAVSSRLNSTWGGNL
MAB_3646c|M.abscessus_ATCC_199      FQQLGVIPDVVAFGKKTQVCGVMAGGRVDEVDDNVFAVSSRINSTWGGNL
MLBr_00485|M.leprae_Br4923          CEHDGIVPDLICTAKG-IADGLPLAAVTGRAEIMNAPHVSGLGGTFGGNP
TH_3529|M.thermoresistible__bu      HQHDGITPDVVTLAKG-LGGGLPIGACLAVGPAGDLLTPGMHGSTFGGNP
                                     :: .: **::  .*     *:  .              .  ..*:*** 

Mflv_4796|M.gilvum_PYR-GCK          VDMVRARRILEVIERDGLFDNAAQRGRHLRDGLAGLAVEFPGLVRDVRGR
Mvan_1652|M.vanbaalenii_PYR-1       ADMVRARRILEVIEVDGLFDRAAESGRYLRDGLDGLAADFPVLVRDVRGR
MSMEG_1764|M.smegmatis_MC2_155      VDMVRSRRILEVIERDGLLDNARDMGAYLLDELRVLATRFPGVVVDPRGR
Mb3318c|M.bovis_AF2122/97           TDMVRARRILEVIEAEGLFERAVQHGKYLRARLDELAADFPAVVLDPRGR
Rv3290c|M.tuberculosis_H37Rv        TDMVRARRILEVIEAEGLFERAVQHGKYLRARLDELAADFPAVVLDPRGR
MMAR_1243|M.marinum_M               TDMVRARRILEVIEAEGLVDNAAEQGRYLRAQFDELAKDLPAVVLHPRGR
MUL_2644|M.ulcerans_Agy99           TDMVRSRRILEVIEAEGLVDNAAEQGRYLRAQFDELAKDLPAVVLHPRGR
MAV_4262|M.avium_104                ADMVRARRILEVIEADELFEHAARQGAYLLRGLHDLAREFPGLVLDVRGR
MAB_3646c|M.abscessus_ATCC_199      VDMVRSRRILEVVEAQRLFANAMRMGEYLLERLQTLAVRHDAVG-DVRGR
MLBr_00485|M.leprae_Br4923          VACAAALATITTIENDGLIQRAQQIERLITDRLLRLQDAD-DRIGDVRGR
TH_3529|M.thermoresistible__bu      VCTAAAVAVLGALAEGDLINRADVLGKKLSHGIEELRHP---LVDHVRGR
                                    .  . :   : .:    *. .*      :   :  *         . ***

Mflv_4796|M.gilvum_PYR-GCK          GLMCAFSMPSARQ--------RDELLARLWECG-VIMLGCGTDSVRFRPA
Mvan_1652|M.vanbaalenii_PYR-1       GLMCAFSMPSAAQ--------RDALIAGLWDCG-VIMLGSGPDSVRFRPA
MSMEG_1764|M.smegmatis_MC2_155      GLMCAFSMPTPED--------RDALIRKLWDRH-VIMLPSGADSVRFRPA
Mb3318c|M.bovis_AF2122/97           GLMCAFSLPTTAD--------RDELIRQLWQRA-VIVLPAGADTVRFRPP
Rv3290c|M.tuberculosis_H37Rv        GLMCAFSLPTTAD--------RDELIRQLWQRA-VIVLPAGADTVRFRPP
MMAR_1243|M.marinum_M               GLMCAFDLPTTAD--------RDELIQRLWQRA-VIALPAGKVSVRFRPA
MUL_2644|M.ulcerans_Agy99           GLMCAFDLPTTAD--------RDELIQRLWQRA-VIALPAGKVSVRFRPA
MAV_4262|M.avium_104                GLMCAFSLPTTAD--------RDELIGRLWRGG-VIVLPTGDDGVRFRPA
MAB_3646c|M.abscessus_ATCC_199      GLMCAFSLPTAEE--------RDHLVQRLWADERVILLPSGENSVRFRPP
MLBr_00485|M.leprae_Br4923          GAMIAVELVKSGTAEPDPELTEKVATAAHATGVIILTCGMFGNIIRLLPP
TH_3529|M.thermoresistible__bu      GLLCGVVLNAP----------QAKAAEAAARDAGFLVNAAAPEVIRLAPP
                                    * : .. :  .          .            .:        :*: *.

Mflv_4796|M.gilvum_PYR-GCK          LTVNDDEIDAALTAVAAVLRTMAVPQAG
Mvan_1652|M.vanbaalenii_PYR-1       LTVSTAELDAALDAVRAVLRTM------
MSMEG_1764|M.smegmatis_MC2_155      LPVTRAEIDACLDAVRAVLSER------
Mb3318c|M.bovis_AF2122/97           LTVSTAEIDAAIAAVRSALPVVT-----
Rv3290c|M.tuberculosis_H37Rv        LTVSTAEIDAAIAAVRSALPVVT-----
MMAR_1243|M.marinum_M               LTVGRDEIDLAIAAVRSALSAMT-----
MUL_2644|M.ulcerans_Agy99           LTVGRDEIDLAIAAVRSALSAMT-----
MAV_4262|M.avium_104                LTVSRGEIDAAIGAVRDALPTLG-----
MAB_3646c|M.abscessus_ATCC_199      LIVSAEEIDAAVAAVSRVLALR------
MLBr_00485|M.leprae_Br4923          LTISDELLAEGLDILSRILGDF------
TH_3529|M.thermoresistible__bu      LIITETQIDEFLAALPGVLDTAKEAS--
                                    * :    :   :  :   *