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TRKPVMADVARLAGVSHQTVSRVINGSPSIRPATRRRVEDAIAQLGYRPNTAARALVTNRSGIIGIIGTN TGLYGPSSVQRAVEEAAREAGYFSSAVPLASVTHQAIRGAVEHLSRLSVEAIVMVAAQQDALTLVQSEDF GVPVIVVEGDLSGAGLTVGVDQVGAARKATQHLIDLGHTAIAHVSGPPNFPEAAGRTKGYLDAMLAARLV PHPDWHGDWSAARGYEIGEKIAAQREITAVFVANDQMAIGLLHALHEAGVRVPDDVSVVGFDDIPEAAYL IPALTTIRQDFAAVGRRAISLVTAQLSGVETDTALLPADLVVRASTAPPPTTK*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. smegmatis MC2 155 | MSMEG_1708 | - | - | 100% (334) | ribose operon repressor, putative |
| M. smegmatis MC2 155 | MSMEG_2636 | - | 3e-36 | 34.21% (342) | regulatory protein, LacI |
| M. smegmatis MC2 155 | MSMEG_0592 | - | 5e-34 | 33.83% (334) | putative rhamnose catabolism operon transcriptional regulator |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb3606c | - | 1e-17 | 25.56% (356) | transcriptional regulatory protein LacI-family |
| M. gilvum PYR-GCK | Mflv_1457 | - | 4e-22 | 28.65% (363) | periplasmic binding protein/LacI transcriptional regulator |
| M. tuberculosis H37Rv | Rv3575c | - | 1e-17 | 25.56% (356) | transcriptional regulatory protein LacI-family |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | - | - | - | - | - |
| M. marinum M | MMAR_5070 | - | 6e-19 | 25.07% (355) | PurR family transcriptional regulator |
| M. avium 104 | MAV_5263 | - | 4e-21 | 31.45% (337) | transcriptional regulator, LacI family protein |
| M. thermoresistible (build 8) | - | - | - | - | - |
| M. ulcerans Agy99 | MUL_4146 | - | 4e-19 | 25.07% (355) | PurR family transcriptional regulator |
| M. vanbaalenii PYR-1 | Mvan_0385 | - | 3e-32 | 32.15% (339) | periplasmic binding protein/LacI transcriptional regulator |
CLUSTAL 2.0.9 multiple sequence alignment
MMAR_5070|M.marinum_M ---------MSPTPRRRATLASLAAELKVSRSTISNAFNRPDQ--LSAEL
MUL_4146|M.ulcerans_Agy99 ---------MSPTPRRRATLASLAAELKVSRSTISNAFNRPDQ--LSVEL
Mb3606c|M.bovis_AF2122/97 ---------MSPTPRRRATLASLAAELKVSRTTVSNAFNRPDQ--LSADL
Rv3575c|M.tuberculosis_H37Rv ---------MSPTPRRRATLASLAAELKVSRTTVSNAFNRPDQ--LSADL
Mflv_1457|M.gilvum_PYR-GCK -------MSRSPTPRRRATLASLAAELKVSRTTVSNAYNRPDQ--LSAEL
MSMEG_1708|M.smegmatis_MC2_155 -------------MTRKPVMADVARLAGVSHQTVSRVINGSPS--IRPAT
Mvan_0385|M.vanbaalenii_PYR-1 ---------MSTPRRRRPTMADVAERAGVSRTLVSFILDGKPG--ASDET
MAV_5263|M.avium_104 MTGPQGNGNSSSNKAARPTTADVARLAGVSTATVSYVLNNARGRRISPDT
:.. *.:* ** :* :
MMAR_5070|M.marinum_M RERVLATAKRMGYPGPDPVARSLRTRKAGAVGLVMAEPLTYFFSDPAARD
MUL_4146|M.ulcerans_Agy99 RERVLATAKRMGYPGPDPVARSLRTRKAGAVGLVMAEPLTYFFSDPAARD
Mb3606c|M.bovis_AF2122/97 RERVLATAKRLGYAGPDPVARSLRTRKAGAVGLVMAEPLTYFFSDPAARD
Rv3575c|M.tuberculosis_H37Rv RERVLATAKRLGYAGPDPVARSLRTRKAGAVGLVMAEPLTYFFSDPAARD
Mflv_1457|M.gilvum_PYR-GCK RERVLSTAKRLGYPGPDPVARSLRTRRAGAVGLVITEPLNYSFSDPAALD
MSMEG_1708|M.smegmatis_MC2_155 RRRVEDAIAQLGYR-PNTAARALVTNRSGIIGIIGTN--TGLYGPSSVQR
Mvan_0385|M.vanbaalenii_PYR-1 RRRVLAIADEIGYR-PDSAARLLAQGRSRTLGVMTDVR------QLFQAE
MAV_5263|M.avium_104 RDAVYRAAKLLGYR-PNLAARNLARGKSGVVLYVVPHVAVGEMPMQAGSR
* * :** *: .** * :: : :
MMAR_5070|M.marinum_M FVTGVAQSCEELGQGLLLVAVGASRSLEDGTAAVLNAGVDGFVVYSVRDD
MUL_4146|M.ulcerans_Agy99 FVTGVAQSCEELGQGLLLVAVGASRSLEDGTAAVLNAGVDGFVVYSVRDD
Mb3606c|M.bovis_AF2122/97 FVAGVAQSCEELGQGLQLVSVGSSRSLADGTAAVLGAGVDGFVVYSVGDD
Rv3575c|M.tuberculosis_H37Rv FVAGVAQSCEELGQGLQLVSVGSSRSLADGTAAVLGAGVDGFVVYSVGDD
Mflv_1457|M.gilvum_PYR-GCK FVAGLAESCEAVGQGLLLVAVGPNRSVAEGSAAVLAAGVDGFVVYSASDD
MSMEG_1708|M.smegmatis_MC2_155 AVEEAAREAGYFSSAVPLASVT-HQAIRGAVEHLSRLSVEAIVMVAAQQD
Mvan_0385|M.vanbaalenii_PYR-1 LVTHIYPAAERLGYEVLLSANLPDRTEATVVDSLLSHRCGALILLGPTGD
MAV_5263|M.avium_104 MTTALAREG---LLQVQVFETDDDQHVVDAIANLDPVAVTSLFPLSAAAR
. : : : : .:. .
MMAR_5070|M.marinum_M DPYLQVVLQRRLPVVVVDQPK---ELAGVSRVGIDDRAAMRKIADYVLGL
MUL_4146|M.ulcerans_Agy99 DPYLQVVLQRRLPVVVVDQPK---ELAGVSRVGIDDRAAMRKIADYVLSL
Mb3606c|M.bovis_AF2122/97 DPYLQVVLQRRLPVVVVDQPK---DLSGVSRVGIDDRAAMRELAGYVLGL
Rv3575c|M.tuberculosis_H37Rv DPYLQVVLQRRLPVVVVDQPK---DLSGVSRVGIDDRAAMRELAGYVLGL
Mflv_1457|M.gilvum_PYR-GCK DPYLPAVMERHLPVVVVDQPR---DVPGASQVRIDDRAAMRSLAEHVIDL
MSMEG_1708|M.smegmatis_MC2_155 ALTLVQSEDFGVPVIVVEGDL---SGAGLT-VGVDQVGAARKATQHLIDL
Mvan_0385|M.vanbaalenii_PYR-1 QSFLEKLAQRAPVVVACRRLTGLNQQTPLATVRTNDAKGIRQAVDYLVGL
MAV_5263|M.avium_104 R----AVTEAGIPHIEIGTLP---------ALNDPHLSVGEMRIAHLVER
: : : . . :::
MMAR_5070|M.marinum_M GHRQIGLLTMRLGRDRRQD----LVDAERLKSPTFDVQRERITGVWEAMT
MUL_4146|M.ulcerans_Agy99 GHRQIGLLTMRLGRDRRQD----LVDAERLKSPTFDVQRERITGVWEAMT
Mb3606c|M.bovis_AF2122/97 GHRELGLLTMRLGRDRRQD----LVDAERLRSPTFDVQRERIVGVWEAMT
Rv3575c|M.tuberculosis_H37Rv GHRELGLLTMRLGRDRRQD----LVDAERLRSPTFDVQRERIVGVWEAMT
Mflv_1457|M.gilvum_PYR-GCK GHREIGLLTMRLGRDWPHGPGPALADPERVRAPNFHVQCERIHGVYDAMT
MSMEG_1708|M.smegmatis_MC2_155 GHTAIAHVSG---------------------PPNFPEAAGRTKGYLDAML
Mvan_0385|M.vanbaalenii_PYR-1 GHRRIHHVDG----------------------GRDPGSADRSRAYKAAMR
MAV_5263|M.avium_104 GHRRIAFAYTG-------------------IARWRPLGDYWFEGVSRAAR
** : . *
MMAR_5070|M.marinum_M AAGVDPESLTVVESYEHLPTSGGDAAKVALEANPRITALMCTADILALSA
MUL_4146|M.ulcerans_Agy99 AAGVDPESLTVVESYEHLPTSGGDAAKVALEANPRITALMCTADILALSA
Mb3606c|M.bovis_AF2122/97 AAGVDPDSLTVVESYEHLPTSGGTAAKVALQANPRLTALMCTADILALSA
Rv3575c|M.tuberculosis_H37Rv AAGVDPDSLTVVESYEHLPTSGGTAAKVALQANPRLTALMCTADILALSA
Mflv_1457|M.gilvum_PYR-GCK AAGLDPASLTLVESYEHLPTSGGAGADIALEANPRITALMCTADVLALSA
MSMEG_1708|M.smegmatis_MC2_155 AARLVP----HPDWHGDWSAARGYEIGEKIAAQREITAVFVANDQMAIGL
Mvan_0385|M.vanbaalenii_PYR-1 AHGLAEEIEVIPGAHN--EDAGAAAARAMLAAPTLPTAVLAGNDRCALGI
MAV_5263|M.avium_104 LRGLPP-----VRADEVILDTAASVVSAWVRDG--VTAVCAQSDEIACLV
: : . : **: * *
MMAR_5070|M.marinum_M MDYLRGHGIYVPGQMTVTGFDGVPEAI--SRGLTTVSQPSLQKGRRAGEL
MUL_4146|M.ulcerans_Agy99 MDYLRGHGIYVPGQMTVTGFDGVPEAI--SRGLTTVSQPSLQKGRRAGEL
Mb3606c|M.bovis_AF2122/97 MDYLRAHGIYVPGQMTVTGFDGVPEAL--SRGLTTVAQPSLHKGHRAGEL
Rv3575c|M.tuberculosis_H37Rv MDYLRAHGIYVPGQMTVTGFDGVPEAL--SRGLTTVAQPSLHKGHRAGEL
Mflv_1457|M.gilvum_PYR-GCK MDHLRAKGIYVPGQMTVTGFDGVPEAR--QRGLTTVAQPGVEKGRRAGEL
MSMEG_1708|M.smegmatis_MC2_155 LHALHEAGVRVPDDVSVVGFDDIPEAAYLIPALTTIRQDFAAVGRRAISL
Mvan_0385|M.vanbaalenii_PYR-1 LDVFTRAGVDVPAQVSLMGYDDTRLSENPRIDLSTIHQDAAEIARHAVQL
MAV_5263|M.avium_104 LYGIHQAGLRCPGDLAVMGVDASPMGMVSTPPLTTVQFDPCAVADAALAA
: : *: * :::: * * . *:*: . *
MMAR_5070|M.marinum_M LQNPPRSG--LPVVELLDTELIRGRTAGPPA---------------
MUL_4146|M.ulcerans_Agy99 LQNPPRSG--LPVVELLDTELIRGRTAGPPA---------------
Mb3606c|M.bovis_AF2122/97 LLKPPRSG--LPVIEVLDTELVRGRTAGPPA---------------
Rv3575c|M.tuberculosis_H37Rv LLKPPRSG--LPVIEVLDTELVRGRTAGPPA---------------
Mflv_1457|M.gilvum_PYR-GCK LHNPPRSG--LPVVEVLDTEVIRGRTSGPPA---------------
MSMEG_1708|M.smegmatis_MC2_155 VTAQLSGV--ETDTALLPADLVVRASTAPPPTTK------------
Mvan_0385|M.vanbaalenii_PYR-1 AVQMLVEGPPHAMDVVLEPTLVVRGTTAPPRGGPAARSGIADTIEG
MAV_5263|M.avium_104 VFERLGHAAPPSPELTDIARLVVRSST-------------------
. . :: ::