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MLAEDMTSASGVAAETVVAVRNVSCTLGGRTVLDDVSLDVRRGQVVVLIGPSGAGKTTLLRSLNHLEEVD TGTILIGGVPIGHRSLTDKRKVGTAELARRRREIGFVFQHFNLFPHMTAAENVWNAPVRVLGTPKGKAEQ DALALLERVGLGDKADSRPSQLSGGQQQRVAIARALAMRPKVMLFDEPTSALDVEMVGEVLAVMRELAAE HMTMVVVTHEMRFAREVADRIVVMDAGRIIEDAPPDELFENPRHERTKAFLSTIR
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. smegmatis MC2 155 | MSMEG_1614 | - | - | 100% (265) | glutamine transport ATP-binding protein GlnQ |
| M. smegmatis MC2 155 | MSMEG_3237 | - | 3e-77 | 55.38% (260) | ATP-binding protein |
| M. smegmatis MC2 155 | MSMEG_6593 | - | 9e-74 | 55.56% (252) | ATP-binding protein |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb2419c | cysA1 | 8e-41 | 39.52% (248) | sulfate-transport ATP-binding protein ABC transporter CysA1 |
| M. gilvum PYR-GCK | Mflv_3581 | - | 6e-76 | 57.31% (253) | ABC transporter related |
| M. tuberculosis H37Rv | Rv2397c | cysA1 | 8e-41 | 39.52% (248) | sulfate-transport ATP-binding protein ABC transporter CysA1 |
| M. leprae Br4923 | MLBr_01089 | - | 1e-36 | 38.16% (228) | putative ABC-transport protein, ATP-binding component |
| M. abscessus ATCC 19977 | MAB_4237c | - | 3e-71 | 54.40% (250) | amino acid ABC transporter ATP-binding protein |
| M. marinum M | MMAR_0060 | - | 1e-61 | 51.42% (247) | glutamine ABC transporter, ATP-binding protein |
| M. avium 104 | MAV_0058 | - | 2e-61 | 50.20% (251) | ABC transporter, ATP-binding protein |
| M. thermoresistible (build 8) | TH_1784 | - | 5e-72 | 56.30% (254) | ABC transporter, ATP-binding protein GluA |
| M. ulcerans Agy99 | MUL_3658 | cysA1 | 1e-40 | 39.52% (248) | sulfate-transport ATP-binding protein ABC transporter CysA1 |
| M. vanbaalenii PYR-1 | Mvan_2834 | - | 4e-76 | 55.81% (258) | ABC transporter-related protein |
CLUSTAL 2.0.9 multiple sequence alignment
Mb2419c|M.bovis_AF2122/97 ----------MT------YAIVVADATKRYG-DFVALDHVDFVVPTGSLT
Rv2397c|M.tuberculosis_H37Rv ----------MT------YAIVVADATKRYG-DFVALDHVDFVVPTGSLT
MUL_3658|M.ulcerans_Agy99 ----------MTGPGTGGHAIVVRDAFKQYG-DFVALDHVDFVVPAGSLT
MMAR_0060|M.marinum_M --------MTRQDAGRQPVCLAARSIHQTLG-GSVVLRGVDLEVPAGTTA
MAV_0058|M.avium_104 --------MS-NPASRASVSLACKDIHQTLN-GNAVLRGVDLDTPAGSTV
TH_1784|M.thermoresistible__bu MDSAGADVAVADPAAEAVPMISMRGVNKYFG-SLHVLRDINLDVARGQVV
MSMEG_1614|M.smegmatis_MC2_155 ---MLAEDMTSASGVAAETVVAVRNVSCTLG-GRTVLDDVSLDVRRGQVV
Mflv_3581|M.gilvum_PYR-GCK ---------MTTSENSAHPMVKAELVCKDFG-ALKVLKGITLEVQKGQVL
Mvan_2834|M.vanbaalenii_PYR-1 ---------MTADAVSAKPMVKAELVCKDFG-ALKVLKGITLEVQKGQVL
MAB_4237c|M.abscessus_ATCC_199 -----------------MSTIEVRGVRKSYG-QVTALRDVNLTVHQGEVT
MLBr_01089|M.leprae_Br4923 -----------------MAEIVLEHVNKNYPNGATAVHDLSITVADGEFL
: .: : : . *
Mb2419c|M.bovis_AF2122/97 ALLGPSGSGKSTLLRTIAGLDQPDTGTITINGRDVTRVP-----------
Rv2397c|M.tuberculosis_H37Rv ALLGPSGSGKSTLLRTIAGLDQPDTGTITINGRDVTRVP-----------
MUL_3658|M.ulcerans_Agy99 ALLGPSGSGKSTLLRTIAGLDQPDSGNITINGRDVTRVP-----------
MMAR_0060|M.marinum_M AVIGPSGSGKSTLLRTLNRLHEPDSGDILLDGRSVLRD------------
MAV_0058|M.avium_104 AVIGPSGSGKSTLLRTLNRLYEPDRGDILLDGRSVLHD------------
TH_1784|M.thermoresistible__bu VVLGPSGSGKSTLCRTLNRLEPIDSGAISIDGVALPAEGR----------
MSMEG_1614|M.smegmatis_MC2_155 VLIGPSGAGKTTLLRSLNHLEEVDTGTILIGGVPIGHRSLTDKRKVGTA-
Mflv_3581|M.gilvum_PYR-GCK VLVGPSGSGKSTLLRCINHLETVSAGRLYVDGTLVGYHERGGKLYEMKPR
Mvan_2834|M.vanbaalenii_PYR-1 VLVGPSGSGKSTFLRCINHLETVSAGRLYVDGALVGYNERGGKLHEMKPR
MAB_4237c|M.abscessus_ATCC_199 VIIGPSGSGKSTLLRALNHLEKVDAGTIRIDGELIGYRQRGSVLYELPER
MLBr_01089|M.leprae_Br4923 ILIGPSGCGKTTTLNMIAGLEDISSGELRIDGDRVNEKAP----------
::****.**:* . : * . * : :.* :
Mb2419c|M.bovis_AF2122/97 ---PQRRGIGFVFQHYAAFKHLTVRDNVAFG-LKIRKRPKAEIKAKVDNL
Rv2397c|M.tuberculosis_H37Rv ---PQRRGIGFVFQHYAAFKHLTVRDNVAFG-LKIRKRPKAEIKAKVDNL
MUL_3658|M.ulcerans_Agy99 ---PQRRGIGFVFQHYAAFKHLTVRDNVAYG-LKIRKRPKAEIRDKVDNL
MMAR_0060|M.marinum_M NPNDLRQRIGMVFQHFNLFPHRNVVDNVTLAPRKLRGLSNEEARMLALDQ
MAV_0058|M.avium_104 DPDQLRQRIGMVFQHFNLFPHRTVLDNVALAPRKLRRLPAEAARELALTQ
TH_1784|M.thermoresistible__bu ELARLRADVGMVFQQFNLFAHKTIVDNVALGPMKVRKTPREQARAEAMAL
MSMEG_1614|M.smegmatis_MC2_155 ELARRRREIGFVFQHFNLFPHMTAAENVWNAPVRVLGTPKGKAEQDALAL
Mflv_3581|M.gilvum_PYR-GCK DVARQRRDVGMVFQHFNLFPHRTALGNVVEAPIQVKGVKKDEAVTRGREL
Mvan_2834|M.vanbaalenii_PYR-1 DVAKQRRDVGMVFQHFNLFPHRTALGNVVEAPIQVKGVRKAQAIEKGKEL
MAB_4237c|M.abscessus_ATCC_199 AILRQRSQVGFVFQNFNLFPHLTVLENVIEAPLAARRAPRAELEAEATRL
MLBr_01089|M.leprae_Br4923 ----KDRDIAMVFQSYALYPHMTVRQNIAFP-LMLAKVKKAEIAQKVSET
:.:*** : : * . *:
Mb2419c|M.bovis_AF2122/97 LQVVGLSGFQSRYPNQLSGGQRQRMALARALAVDPEVLLLDEPFGALDAK
Rv2397c|M.tuberculosis_H37Rv LQVVGLSGFQSRYPNQLSGGQRQRMALARALAVDPEVLLLDEPFGALDAK
MUL_3658|M.ulcerans_Agy99 LEVVGLSGFHGRYPDQLSGGQRQRMALARALAVDPEVLLLDEPFGALDAK
MMAR_0060|M.marinum_M LDRVGLKHKANARPDMLSGGQQQRVAIARALAMAPQVMFFDEATSALDPE
MAV_0058|M.avium_104 LDRVGLKHKAGARPATLSGGQQQRVAIARALAMSPQVMFFDEATSALDPE
TH_1784|M.thermoresistible__bu LERVGVADQADKYPAQLSGGQQQRVAIARSLAMNPKVMLFDEPTSALDPE
MSMEG_1614|M.smegmatis_MC2_155 LERVGLGDKADSRPSQLSGGQQQRVAIARALAMRPKVMLFDEPTSALDVE
Mflv_3581|M.gilvum_PYR-GCK LAQVGLADKADAYPAQLSGGQQQRVAIARALAMDPKLMLFDEPTSALDPE
Mvan_2834|M.vanbaalenii_PYR-1 LAQVGLADKAGAYPAQLSGGQQQRVAIARALAMDPKLMLFDEPTSALDPE
MAB_4237c|M.abscessus_ATCC_199 LERVGVADKAAQYPRRLSGGQQQRVAIARALALRPKVILFDEPTSALDPE
MLBr_01089|M.leprae_Br4923 AQILDLTDLLDRKPSQLSGGQRQRVAMGRAIVRHPKAFLMDEPLSNLDAK
:.: * *****:**:*:.*::. *: :::**. . ** :
Mb2419c|M.bovis_AF2122/97 VREELRAWLRRLHDEVHVTTVLVTHDQAEALDVADRIAVLHKGRIEQVGS
Rv2397c|M.tuberculosis_H37Rv VREELRAWLRRLHDEVHVTTVLVTHDQAEALDVADRIAVLHKGRIEQVGS
MUL_3658|M.ulcerans_Agy99 VREDLRAWLRRLHDEVHVTTVLVTHDQAEALDVADRIAVLNSGRIEQVGS
MMAR_0060|M.marinum_M MVKGILALIADLGADG-MTMVVVTHEMGFARSTSDAVVFMDHGTVVEAGP
MAV_0058|M.avium_104 MVKGILQLIADLGAEG-MTMVVVTHEMGFARSASDAVIFMDHGKVVESGP
TH_1784|M.thermoresistible__bu MINEVLAVMSALAADG-MTMLVVTHEMGFARRASDRVVFMSDGAIVEDAE
MSMEG_1614|M.smegmatis_MC2_155 MVGEVLAVMRELAAEH-MTMVVVTHEMRFAREVADRIVVMDAGRIIEDAP
Mflv_3581|M.gilvum_PYR-GCK LVGEVLAVMKKLAAQG-MTMVVVTHEMGFAREVADELVFMDEGVVVERGN
Mvan_2834|M.vanbaalenii_PYR-1 LVGEVLGVMKKLAAQG-MTMVVVTHEMGFAREVADELVFMDAGVVVERGA
MAB_4237c|M.abscessus_ATCC_199 LVTEVLDVIAQLARDG-ATLVIVTHEIGLAREIADTVVFMDRGAIVEQGP
MLBr_01089|M.leprae_Br4923 LRVRTRGEIARLQRRLGATTVYVTHDQTEAMTLGDRVVVMRSGVVQQIGT
: : * * : ***: * .* : .: * : : .
Mb2419c|M.bovis_AF2122/97 PTDVYDAPANAFVMSFLGAVSTLNGSLVRPHD------------------
Rv2397c|M.tuberculosis_H37Rv PTDVYDAPANAFVMSFLGAVSTLNGSLVRPHD------------------
MUL_3658|M.ulcerans_Agy99 PTEVYDAPTNAFVMSFLGAVSALNGALVRPHD------------------
MMAR_0060|M.marinum_M PEQLFEAARTERLQRFLAQVL-----------------------------
MAV_0058|M.avium_104 PEQIFEAAETERLQRFLSQVL-----------------------------
TH_1784|M.thermoresistible__bu PARFFEDPQTDRARDFLGKILHH---------------------------
MSMEG_1614|M.smegmatis_MC2_155 PDELFENPRHERTKAFLSTIR-----------------------------
Mflv_3581|M.gilvum_PYR-GCK PREVMSNPQHERTKAFLSKVM-----------------------------
Mvan_2834|M.vanbaalenii_PYR-1 PREVMANPQHERTKAFLSKVM-----------------------------
MAB_4237c|M.abscessus_ATCC_199 PKEVLDSPSHPRTASFLSKVLS----------------------------
MLBr_01089|M.leprae_Br4923 PDELYERPVNLFVAGFIGSPVMNFFPAKLTPNGLTLPLGELNLSRDVQAM
* . . *:.
Mb2419c|M.bovis_AF2122/97 IRVGRTPNMAVAAADGTAGSTGVLRAVVDRVVVLGFEVRVELTSAATGGA
Rv2397c|M.tuberculosis_H37Rv IRVGRTPNMAVAAADGTAGSTGVLRAVVDRVVVLGFEVRVELTSAATGGA
MUL_3658|M.ulcerans_Agy99 IRVGRTPEMAVAAADGTGESTGVTRAVVDRIVVLGFEVRVELTSAATGGA
MMAR_0060|M.marinum_M --------------------------------------------------
MAV_0058|M.avium_104 --------------------------------------------------
TH_1784|M.thermoresistible__bu --------------------------------------------------
MSMEG_1614|M.smegmatis_MC2_155 --------------------------------------------------
Mflv_3581|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_2834|M.vanbaalenii_PYR-1 --------------------------------------------------
MAB_4237c|M.abscessus_ATCC_199 --------------------------------------------------
MLBr_01089|M.leprae_Br4923 IGQHPVPDRVIVGVRPEHLTDAKLIDAHQHGTVLTFKVKVDLVESLGADK
Mb2419c|M.bovis_AF2122/97 FTAQITRGDAEALALREGDTVYVRATRVPPIAGGVSGVDDAGVERVKVTS
Rv2397c|M.tuberculosis_H37Rv FTAQITRGDAEALALREGDTVYVRATRVPPIAGGVSGVDDAGVERVKVTS
MUL_3658|M.ulcerans_Agy99 FTAQITRGDAEALALQEGDTVYVRATRVPPIAGAAPAVPDDGAGSTPRAA
MMAR_0060|M.marinum_M --------------------------------------------------
MAV_0058|M.avium_104 --------------------------------------------------
TH_1784|M.thermoresistible__bu --------------------------------------------------
MSMEG_1614|M.smegmatis_MC2_155 --------------------------------------------------
Mflv_3581|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_2834|M.vanbaalenii_PYR-1 --------------------------------------------------
MAB_4237c|M.abscessus_ATCC_199 --------------------------------------------------
MLBr_01089|M.leprae_Br4923 YIYFTTTGCDVYSAQLDELASELEVRENQFVARVSAESKMAIGESIELAF
Mb2419c|M.bovis_AF2122/97 T-----------------------
Rv2397c|M.tuberculosis_H37Rv T-----------------------
MUL_3658|M.ulcerans_Agy99 QIGVGGQ-----------------
MMAR_0060|M.marinum_M ------------------------
MAV_0058|M.avium_104 ------------------------
TH_1784|M.thermoresistible__bu ------------------------
MSMEG_1614|M.smegmatis_MC2_155 ------------------------
Mflv_3581|M.gilvum_PYR-GCK ------------------------
Mvan_2834|M.vanbaalenii_PYR-1 ------------------------
MAB_4237c|M.abscessus_ATCC_199 ------------------------
MLBr_01089|M.leprae_Br4923 GTAKIAVFDADSGVNLTVSAPTDA