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MRRARQVSALLFGLVIVLNAAVVGCRAAEAPVATDPVVVHTASGTVRGLVAEGHRLFAGIPYAAPPVGSL RFAAPEPAASWPGERDATRPGPRCVQDPDADLEHGDNSGEDCLTLNVWTPPVGKDLRPVMVWIHGGGFVN GSSDVYDASRLASRGDIVVVTVNYRLGTLGFLAHPALEAPGEVGNYGIADQQAALRWVRDNIAAFGGDPQ RVTLAGESAGGTSVCDHLVAPGSAGLFDAVVLMSAPCQVQADLPTAEQRSVAYAAEAGCPDPASAGDCLR ALPVDRLRKPVWYFNIGSDQMTTPVTGTAMLPRAPLRSLGEAPDVPVLIGTTRDEFTLFVALRYLRQDQR FTPEEYPELLRQTFGADADAVGAHYPLERYGGAAQAYSAAVTDSAFSCVAEQMADELPGTVYAYEFADRD APAPEVMRTLPFPVGASHSLELRYLFDVGGAPPLNPRQQALADQMIGYWSQFVRTGDPAAEDQPEWPAYS ASESSGRQWMSLRPDGSRMASDFGEEHQCPFWVGLKEK
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. smegmatis MC2 155 | MSMEG_1432 | - | - | 100% (528) | acetylcholinesterase |
| M. smegmatis MC2 155 | MSMEG_0470 | - | 7e-60 | 35.71% (504) | para-nitrobenzyl esterase |
| M. smegmatis MC2 155 | MSMEG_0611 | - | 9e-58 | 39.03% (474) | para-nitrobenzyl esterase |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb2071c | lipT | 2e-50 | 35.03% (491) | carboxylesterase LipT |
| M. gilvum PYR-GCK | Mflv_5051 | - | 0.0 | 62.62% (519) | carboxylesterase, type B |
| M. tuberculosis H37Rv | Rv2045c | lipT | 2e-50 | 35.03% (491) | carboxylesterase LipT |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | MAB_3803c | - | 1e-124 | 47.89% (522) | carboxylesterase |
| M. marinum M | MMAR_4363 | - | 5e-56 | 35.46% (502) | carboxylesterase |
| M. avium 104 | MAV_0492 | - | 2e-65 | 38.08% (478) | para-nitrobenzyl esterase |
| M. thermoresistible (build 8) | TH_3456 | - | 1e-179 | 60.94% (512) | PUTATIVE Carboxylesterase, type B |
| M. ulcerans Agy99 | MUL_2261 | lipT | 9e-51 | 34.43% (488) | carboxylesterase, LipT |
| M. vanbaalenii PYR-1 | Mvan_1303 | - | 0.0 | 61.33% (525) | carboxylesterase, type B |
CLUSTAL 2.0.9 multiple sequence alignment
Mflv_5051|M.gilvum_PYR-GCK --------MLVALVVAVACGSQAS------PQPAPDPAVVQTSTGPVRGT
Mvan_1303|M.vanbaalenii_PYR-1 MPIPRLGVLAVLMVLVAACGRGDAGDRGHEARSPVDPAVVQTAAGAVRGT
MSMEG_1432|M.smegmatis_MC2_155 MRRAR-QVSALLFGLVIVLNAAVVGCRAAEAPVATDPVVVHTASGTVRGL
TH_3456|M.thermoresistible__bu --------------------------------------VVQTDAGAVRGT
MAB_3803c|M.abscessus_ATCC_199 -------MTRLLVAVLVVLAAAVS----CSPTKAADPTVVTTRAGAVRGH
Mb2071c|M.bovis_AF2122/97 ----------------------MALESATVGSMHERTVRARTATGIVEGF
Rv2045c|M.tuberculosis_H37Rv ----------------------MALESATVGSMHERTVRARTATGIVEGF
MUL_2261|M.ulcerans_Agy99 --------------------------------MHERTVRARTATGVVEGF
MMAR_4363|M.marinum_M -------------------------MTSDIRRMASDGYVVETAYGPVRGA
MAV_0492|M.avium_104 -----------------------------------MSPTVRLAQGVVSGA
. * * *
Mflv_5051|M.gilvum_PYR-GCK VA--------DDHRLFAGIPYAAPPVGALRWQGPRPAPKWDGVRDATAYG
Mvan_1303|M.vanbaalenii_PYR-1 VE--------PDHRLFAGIPYAAPPIGPLRWRDPEPAPRWDGVRDATAFG
MSMEG_1432|M.smegmatis_MC2_155 VA--------EGHRLFAGIPYAAPPVGSLRFAAPEPAASWPGERDATRPG
TH_3456|M.thermoresistible__bu VT--------DRYRFFGGIPYAAAPVGDLRWRAPEPPRSWPQVRDATIPG
MAB_3803c|M.abscessus_ATCC_199 ID--------DQVRVFAAIPYAAPPVGPRRFAEPGPVTPWPDTRDATGPG
Mb2071c|M.bovis_AF2122/97 TR------DGVHR--WRSIPYARAPVGSLRFRAPQPAQPWPGVRHCHTFA
Rv2045c|M.tuberculosis_H37Rv TR------DGVHR--WRSIPYARAPVGSLRFRAPQPAQPWPGVRHCHTFA
MUL_2261|M.ulcerans_Agy99 TR------DGVHR--WRSIPYARAPIGLLRFRAPRPPQPWSGVRHCHGFT
MMAR_4363|M.marinum_M EDGIAAAGSGVRTKSWKGIRYGAPPVGELRFRAPQPPQPWTEIADATAFG
MAV_0492|M.avium_104 ED------GGVYR--FLGMPYAAPPVGDLRWAPPAPPASWAGVRDATRYG
: .: *. .*:* *: * * * ..
Mflv_5051|M.gilvum_PYR-GCK PRCMQDL---DGDLELGRQTDEDCLNLNVWTPPVAGDRPEPKPVMVWIHG
Mvan_1303|M.vanbaalenii_PYR-1 SRCLQDL---AGDLELGRQTDEDCLNLNVWTPAAEPGRP--RAVMVWIHG
MSMEG_1432|M.smegmatis_MC2_155 PRCVQDP---DADLEHGDNSGEDCLTLNVWTPPVGKDLR---PVMVWIHG
TH_3456|M.thermoresistible__bu PRCIQNP---AGDPEGGRNSDEDCLTLNVWTPPPDGVLR---PVLVWIHG
MAB_3803c|M.abscessus_ATCC_199 VECPQP------GQESNLPQTEDCLLLTVTMPRHTQGKV---PVLVWIHG
Mb2071c|M.bovis_AF2122/97 NCAPQQRRYTVMGIGRYQTRSEDCLTLNVVTPE-EPAT-QPLPVMVFIHG
Rv2045c|M.tuberculosis_H37Rv NCAPQQRRYTVMGIGRYQTRSEDCLTLNVVTPE-EPAT-QPLPVMVFIHG
MUL_2261|M.ulcerans_Agy99 HCSPQQRRYTMLGLGKYQPMSEDCLTLNVVAPE-APTH-RPLPVMVFIHG
MMAR_4363|M.marinum_M PVCPQP-VLANMPIDLGAPQDEDCLRLNIWAPA-NTAPGAAKPVMVWLHG
MAV_0492|M.avium_104 NAAIQT---VDTGFDPGAPQSEDCLYLNVWTST-LDVG-ARRPVMVWIHG
. * **** *.: . .*:*::**
Mflv_5051|M.gilvum_PYR-GCK GSFVAGSSG--VYDSRRLVARGDIIVVTVNYRLGALGFLAHPALGPP--G
Mvan_1303|M.vanbaalenii_PYR-1 GSFVAGSGG--IYDARRLAARGDIVVVTLNYRLGAPGFLAHPSLGPP--G
MSMEG_1432|M.smegmatis_MC2_155 GGFVNGSSD--VYDASRLASRGDIVVVTVNYRLGTLGFLAHPALEAP--G
TH_3456|M.thermoresistible__bu GGFVNGGGA--MFNSEWFVERGDIVVVTINYRLGTLGFLAHPELGPP--G
MAB_3803c|M.abscessus_ATCC_199 GAFIAGNGV--DYNARKLAAQGGIAVVTFNYRLGTLGFLAAPGLS----G
Mb2071c|M.bovis_AF2122/97 GGYILGSSATPIYDGAALARRG-CVYVSVNYRLGALGCLDLSSLSTPQIT
Rv2045c|M.tuberculosis_H37Rv GGYILGSSATPIYDGAALARRG-CVYVSVNYRLGALGCLDLSSLSTPQIT
MUL_2261|M.ulcerans_Agy99 GGYILGSSATPIYDGAALARRG-CVYVSVNYRLGALGCLDLSSLSTPDIA
MMAR_4363|M.marinum_M GAYMLGSASQALYDGRRLASSGEVIVVTVNYRLGALGFLDLSSLSHAGRS
MAV_0492|M.avium_104 GGFLNGASSMDLWQGQHLARRG-VTVVSLNYRLGAFGFLAHPQAG-----
*.:: * . ::. :. * *:.*****: * * .
Mflv_5051|M.gilvum_PYR-GCK AVGNYGLADQQAALRWVRDNIANFGGDPARVTVAGESAGAMSVCDHLVAP
Mvan_1303|M.vanbaalenii_PYR-1 EVGNYGLADQQAALRWVRDNIAAFGGDPGKVTVAGESAGAMSVCDHLVAP
MSMEG_1432|M.smegmatis_MC2_155 EVGNYGIADQQAALRWVRDNIAAFGGDPQRVTLAGESAGGTSVCDHLVAP
TH_3456|M.thermoresistible__bu AVGNYGFLDQQAALRWVRANIAGFGGDPDRVTIAGESAGGMAVCDHLAAP
MAB_3803c|M.abscessus_ATCC_199 GIGNYGLLDQEAALRWVRDNIAEFGGDPARVTIAGQSAGGVSVCDLMVSP
Mb2071c|M.bovis_AF2122/97 LDSNVYLRDLVLALRWVHDNIAEFGGDPGNVTIFGESAGAHITATLLAVP
Rv2045c|M.tuberculosis_H37Rv LDSNVYLRDLVLALRWVHDNIAEFGGDPGNVTIFGESAGAHITATLLAVP
MUL_2261|M.ulcerans_Agy99 IDGNLYLRDLVMALQWIQDNIAEFGGDPDNVTIFGESAGAHITATLLAVP
MMAR_4363|M.marinum_M FDSNVGLRDVLAALHWVRENIAAFGGDPANITLFGESAGAGLVTTLLVTP
MAV_0492|M.avium_104 --GNFGLLDWVAALSWVAENIATFGGDPANVTIFGQSAGGAATRALLHTP
.* : * ** *: *** ***** .:*: *:***. . : *
Mflv_5051|M.gilvum_PYR-GCK GSDGLFDAAIVMSG-----LCQSQADLPTAEKRSLDYAAQAGCGG-PVPA
Mvan_1303|M.vanbaalenii_PYR-1 ASQGLFDAAIIMSG-----PCQAQAPLPVAEQRSIEYAAALGCADKATAA
MSMEG_1432|M.smegmatis_MC2_155 GSAGLFDAVVLMSA-----PCQVQADLPTAEQRSVAYAAEAGCPDPASAG
TH_3456|M.thermoresistible__bu GSAGLFHAAIIMSA-----PCQGQVDVDTAEQVSLRYAAEVGCGDPGAAA
MAB_3803c|M.abscessus_ATCC_199 QASGLFRSAIMESA-----PCQAQAPVSSAVRDSTAYAAEVGCPAGPDMA
Mb2071c|M.bovis_AF2122/97 AAKGLFARAISESP-----AAGMVRSREVAAEFAARFANLIGARTQDAAN
Rv2045c|M.tuberculosis_H37Rv AAKGLFARAISESP-----AAGMVRSREVAAEFAARFANLIGARTQDAAN
MUL_2261|M.ulcerans_Agy99 AAKGLFARAISESP-----AAGMVRPREIAAEFATRFARLLGARKHDAAS
MMAR_4363|M.marinum_M AARGLFSRAIAQSS-----PATSVYDRERAQRVAVHLLDKLGVAASDVD-
MAV_0492|M.avium_104 SARGLFHRAVIQSAGYEDYAVVGSPSYQRVTDASERLFEQLGSADIDELR
: *** .: * . : *
Mflv_5051|M.gilvum_PYR-GCK ECLRGLDANALRTPV------WYYDIGDDRLSGPVTGSAVLPTAPPVAFG
Mvan_1303|M.vanbaalenii_PYR-1 ECLRALPGNKLRTPV------WFYEIGDDRLSGPATGSAELPADPVTAFG
MSMEG_1432|M.smegmatis_MC2_155 DCLRALPVDRLRKPV------WYFNIGSDQMTTPVTGTAMLPRAPLRSLG
TH_3456|M.thermoresistible__bu ACLRGLPPEAVAAPV------SYFEFGTEKLSGPVTGTEALPVDPVDAIA
MAB_3803c|M.abscessus_ATCC_199 RCLRALSVDALRDSP------QFTGIG--LPVSPVIGTPELPAAPLDAFT
Mb2071c|M.bovis_AF2122/97 ALMQASPAQLVEAQHHLIR-QGMRKRLGAFPIGPVFGDDYLPMDPVEAMR
Rv2045c|M.tuberculosis_H37Rv ALMQASPAQLVEAQHHLIR-QGMRKRLGAFPIGPVFGDDYLPMDPVEAMR
MUL_2261|M.ulcerans_Agy99 ALMRATAAQLVQTQHRLID-QGMQKRLGAFPIGPTFGDDCLPLDPVEAMR
MMAR_4363|M.marinum_M KLTQLPTAAIVAASTEVFN-EVPVRNPGTLAFVPIVDGDVLTDYPVKVAQ
MAV_0492|M.avium_104 RLPAEQVRQASFDQCGVNPPPGQVHTPANLVWYPTVDGRVMEED-----F
* . :
Mflv_5051|M.gilvum_PYR-GCK DGKAAR-VPVLMGTTRDEWTLFVA-----LQHLRDGKDYAPQEYPRLLAD
Mvan_1303|M.vanbaalenii_PYR-1 AGRAAR-VPVLIGTTRDEWTLFVA-----LQHLRDGRDYTPEEYPRLLAD
MSMEG_1432|M.smegmatis_MC2_155 --EAPD-VPVLIGTTRDEFTLFVA-----LRYLRQDQRFTPEEYPELLRQ
TH_3456|M.thermoresistible__bu EGRVAR-VPVLIGTNRDEFTLFAG-----LRYLREGERFAAEDHPRLLAE
MAB_3803c|M.abscessus_ATCC_199 SGLAASPVPVLIGSNANEATVFEA-----KQYQHRPVPRTAEEYQSVLES
Mb2071c|M.bovis_AF2122/97 SGRVHA-VPLIVGTNAEEGRLFTR----FLG-MLPTNEPMVEELLSGMKP
Rv2045c|M.tuberculosis_H37Rv SGRVHA-VPLIVGTNAEEGRLFTR----FLG-MLPTNEPMVEELLSGMKP
MUL_2261|M.ulcerans_Agy99 AGQSHK-VPLIVGTNADEGRLFTR----FLK-MLPTNKAMIDELLADTEP
MMAR_4363|M.marinum_M EGRSHP-VPLLIGTNKHEAALFRL----MRSPLMPITPRAITSMFTQIAA
MAV_0492|M.avium_104 SGWPAD-VPVMIGCTEHEGRFFVQPTMLYAHPELDPAQVYTQDTLEHMAR
**:::* . .* .* .
Mflv_5051|M.gilvum_PYR-GCK TFGADAPAVEAHYPLTAFSSVAL-AYAATVTDGVFACAGRRWAGDLAETA
Mvan_1303|M.vanbaalenii_PYR-1 TFGADARAVAGRYPLSAFPDVAL-AYAATVTDGILACPAERWARQLSRDA
MSMEG_1432|M.smegmatis_MC2_155 TFGADADAVGAHYPLERYGGAAQ-AYSAAVTDSAFSCVAEQMADELPG--
TH_3456|M.thermoresistible__bu IFGDDAAAVAARYPLEDYPSPAL-AYSAAVTDSLFACLSERLADQLARHQ
MAB_3803c|M.abscessus_ATCC_199 KYGTRATELGRRYPLADFDGNVLGALAAIDTDNSYACPTFAMAEALARRA
Mb2071c|M.bovis_AF2122/97 -------ADRERITAAYPNYPAPSACIQLGGDFAFSSAAWQIAEAHGANA
Rv2045c|M.tuberculosis_H37Rv -------ADRERITAAYPNYPAPSACIQLGGDFAFSSAAWQIAEAHGANA
MUL_2261|M.ulcerans_Agy99 -------ATRERITAAYPNYPESAACIQLGGDFAFNAAAWQIAEAQGVHA
MMAR_4363|M.marinum_M EQPDLQLPTEEEIGLAYSRLRRRARPLSIATDVGFRMPSVWLAEGHSRVA
MAV_0492|M.avium_104 ALGGERAGDILAHYAASGLSAYEALAELITIGVWHEPALASVERFAALGR
.
Mflv_5051|M.gilvum_PYR-GCK PVYFYEFNDRDAPAPDPLRTVPFPVGASHSLELRYLFDTGGA--------
Mvan_1303|M.vanbaalenii_PYR-1 SVYFYEFNDRNAPAPDPLRTLPFPVGASHSLELRYLFDVGGA--------
MSMEG_1432|M.smegmatis_MC2_155 TVYAYEFADRDAPAPEVMRTLPFPVGASHSLELRYLFDVGGA--------
TH_3456|M.thermoresistible__bu PVYSYEFADRDAPAPEPLRTLPFPVGAGHSLELRYLFDVGGA--------
MAB_3803c|M.abscessus_ATCC_199 PVYAYEFADPVAPVEQQYRDAPLPLGASHGSELGYLFDLS----------
Mb2071c|M.bovis_AF2122/97 PTYLYRYDYAPRTLRWSG------FGATHATELFAVFDIYRTRFGALLTA
Rv2045c|M.tuberculosis_H37Rv PTYLYRYDYAPRTLRWSG------FGATHATELFAVFDIYRTRFGALLTA
MUL_2261|M.ulcerans_Agy99 PTYLYRYDYAPRTLRWSG------FGATHATELFAVFDIYRTRFGALLTA
MMAR_4363|M.marinum_M PVYLYRFDYSTPLLKLLL------VRAAHATELPYVWGNLGGPQDPTLRL
MAV_0492|M.avium_104 RAYHYRFARVSPGARTSG------LLAKHSAEIPYLFGGLTP-------A
.* *.: . * *. *: ::.
Mflv_5051|M.gilvum_PYR-GCK PPPSPAQVRLGEQMIDYWASFVKTGD-------PGFPGIDSG--------
Mvan_1303|M.vanbaalenii_PYR-1 PPPDPAQVRLGEQMVDHWAAFVRAGD-------PGWPGVDAG--------
MSMEG_1432|M.smegmatis_MC2_155 PPLNPRQQALADQMIGYWSQFVRTGDPAAEDQ-PEWPAYSASESS-----
TH_3456|M.thermoresistible__bu PALTAAQRALSEQMIDYWSAFVATGVPATDGH-PDWPAHRAAADSGAGPD
MAB_3803c|M.abscessus_ATCC_199 RTMNPESAALSTQMTRYWAQFVKTGNPNVEGQ-PEWPAYISGG-------
Mb2071c|M.bovis_AF2122/97 AADRRAALRVSNEVQRRWRCFSQIGVPG-----DDWPAYTQDD-------
Rv2045c|M.tuberculosis_H37Rv AADRRAALRVSNEVQRRWRCFSQIGVPG-----DDWPAYTQDD-------
MUL_2261|M.ulcerans_Agy99 AADRRHALRVSDEVIRRWRSFSQTGTPG-----EDWPAYTHTR-------
MMAR_4363|M.marinum_M GG-AKTAKAVSKRMRTRWINFATQDNPAGPAGEPDWPAYQDGD-------
MAV_0492|M.avium_104 GSYDEVDAAVSDAVQHAWVEFARTGVPRTPDG-TDFPSYDTTS-------
:. : * * . :*.
Mflv_5051|M.gilvum_PYR-GCK ------------------VMSLQPDGSRMIEDFDRVHQCVFWDGLG----
Mvan_1303|M.vanbaalenii_PYR-1 ------------------VMSLQPDGSRMVETFGEVHQCSFWAGLQ----
MSMEG_1432|M.smegmatis_MC2_155 ---------------GRQWMSLRPDGSRMASDFGEEHQCPFWVGLKEK--
TH_3456|M.thermoresistible__bu ESPTDRDPGDGGPGAGPARMSLRPGGSTVVDDFATEHRCVFWAELAG---
MAB_3803c|M.abscessus_ATCC_199 -----------------AFQRLAPPAPRSEGGFASRHQCGYWR-------
Mb2071c|M.bovis_AF2122/97 ------------------RAVLVFDRRCRIEFDPHQHRRIAWDGFSLAN-
Rv2045c|M.tuberculosis_H37Rv ------------------RAVLVFDRRCRIEFDPHQHRRIAWDGFSLAN-
MUL_2261|M.ulcerans_Agy99 ------------------RAVMVIDRKSRVEIDPHRHRRLAWDGFSLAR-
MMAR_4363|M.marinum_M ------------------RACLVIDKSDRVARDIDAPIRAAWGREVVGFR
MAV_0492|M.avium_104 ------------------RQVVVFDDTTEVRPLDANPVTDMIHTLRAAPT
:
Mflv_5051|M.gilvum_PYR-GCK --
Mvan_1303|M.vanbaalenii_PYR-1 --
MSMEG_1432|M.smegmatis_MC2_155 --
TH_3456|M.thermoresistible__bu --
MAB_3803c|M.abscessus_ATCC_199 --
Mb2071c|M.bovis_AF2122/97 --
Rv2045c|M.tuberculosis_H37Rv --
MUL_2261|M.ulcerans_Agy99 --
MMAR_4363|M.marinum_M --
MAV_0492|M.avium_104 RR