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VMLSSVRRACLAAVLAVLAVLGGVVVTALPDCVHEHCQTMAAAPQGVPQPSPTEPAKLTITPKNNAEDVE PLAPVAVTAVTGTVTSVRMLNDAGKEIAGALSPDGKVWKPATALGYGRTYTMNVVARGPGGMPTRASSTF TTVTPTYQANVYLNGTSGAPLKDGETYGVGMVIVARFDQAITDKASAERRMKVTTSPKAVGSWNWIDDQT AHWRPREYYAPGTKVTVDADIYGARLGEDLYGAQDEKVSFVIGDSHVSIADDNTKQVSVYENGKLVRTMP TSMGMGGTETVNGVTLSFWTPRGIYTVMDKANPVVMDSSTYGLPVGSRLGYRTTIPYATRISVDGIYLHQ LNDTIWAQGNTNVSHGCLNLSGENAQWFYNFSRPGDIVEIRNTGGEPLKPDNNGDWTIPWEQWRKGSALN
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. smegmatis MC2 155 | MSMEG_1322 | - | - | 100% (420) | ErfK/YbiS/YcfS/YnhG family protein |
| M. smegmatis MC2 155 | MSMEG_4745 | - | 8e-81 | 42.18% (377) | ErfK/YbiS/YcfS/YnhG family protein |
| M. smegmatis MC2 155 | MSMEG_0929 | - | 3e-53 | 34.03% (385) | ErfK/YbiS/YcfS/YnhG family protein |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb2547c | lppS | 5e-88 | 42.03% (414) | lipoprotein LppS |
| M. gilvum PYR-GCK | Mflv_2800 | - | 1e-133 | 53.90% (423) | ErfK/YbiS/YcfS/YnhG family protein |
| M. tuberculosis H37Rv | Rv2518c | lppS | 6e-88 | 42.03% (414) | lipoprotein LppS |
| M. leprae Br4923 | MLBr_00426 | lppS | 1e-78 | 40.77% (363) | putative secreted protein |
| M. abscessus ATCC 19977 | MAB_1530 | - | 4e-80 | 41.76% (364) | lipoprotein LppS |
| M. marinum M | MMAR_3872 | lppS | 1e-85 | 41.77% (419) | lipoprotein LppS |
| M. avium 104 | MAV_2751 | - | 1e-144 | 57.77% (412) | ErfK/YbiS/YcfS/YnhG family protein |
| M. thermoresistible (build 8) | TH_1098 | lppS | 3e-82 | 41.96% (398) | PROBABLE CONSERVED LIPOPROTEIN LPPS |
| M. ulcerans Agy99 | MUL_3804 | lppS | 1e-85 | 41.77% (419) | lipoprotein LppS |
| M. vanbaalenii PYR-1 | Mvan_5559 | - | 1e-135 | 55.83% (412) | ErfK/YbiS/YcfS/YnhG family protein |
CLUSTAL 2.0.9 multiple sequence alignment
MMAR_3872|M.marinum_M ---MAPLS-----------RR------RSWLAAILIPVAVLAVACGGSSA
MUL_3804|M.ulcerans_Agy99 --MMAPLS-----------RR------RSWLAAILIPVAVLAVACGGSSA
Mb2547c|M.bovis_AF2122/97 MPKVGIAA-----------QAGRTRVRRAWLTALMMTAVMIGAVACGSGR
Rv2518c|M.tuberculosis_H37Rv MPKVGIAA-----------QAGRTRVRRAWLTALMMTAVMIGAVACGSGR
MLBr_00426|M.leprae_Br4923 ---MGTAT-----------RRVQPKAWRALLTLLVISVVMPG-VACNRGG
TH_1098|M.thermoresistible__bu ---MTRPR-----------WRS-----RWWLITGLLSVVVLALSACSGGG
MAB_1530|M.abscessus_ATCC_1997 ---MTQGR-----------PRLHAGARRRWVATLALPVVAMAVLAGCAGA
MSMEG_1322|M.smegmatis_MC2_155 ---MMLSS----------VRR--ACLAAVLAVLAVLGGVVVTALPDCVHE
MAV_2751|M.avium_104 ---MASKSSDRLVGRILGVRRPRRFLAAVFVVVAVAGAIQLAEAAPCPHG
Mvan_5559|M.vanbaalenii_PYR-1 ---MELGR-----------WRGTARLATALAHLALLGAAVVGVLS--IDG
Mflv_2800|M.gilvum_PYR-GCK ---MLAGR------------RKVVALSVISAVAVLVTASQTSALKSRLTN
:
MMAR_3872|M.marinum_M TPTATKVIENKGTPFADLLVPKLTASVTDGAVGVTVDAPVTVSVSDGVLA
MUL_3804|M.ulcerans_Agy99 TPTATKVIENKGTPFADLLVPKLTASVTDGAVGVTVDAPVTVSVSDGVLA
Mb2547c|M.bovis_AF2122/97 GPAPIKVIADKGTPFADLLVPKLTASVTDGAVGVTVDAPVSVTAADGVLA
Rv2518c|M.tuberculosis_H37Rv GPAPIKVIADKGTPFADLLVPKLTASVTDGAVGVTVDAPVSVTAADGVLA
MLBr_00426|M.leprae_Br4923 GNVPVNVIGDKGTPFADLLVPKLTASVTDGAVGVNVDMPVTVTVADGVLA
TH_1098|M.thermoresistible__bu ASDQPKVITDKGTPYGDLLVPRVTASVTDKAVGVPVDEPVTVSAENGVLG
MAB_1530|M.abscessus_ATCC_1997 TTQEPPKVIDKATPYADLLVPKLAMSVKDGAVGVAVDAPVTVTAGEGVLG
MSMEG_1322|M.smegmatis_MC2_155 HCQTMAAAPQGVPQPSPTEPAKLTITPKNNAEDVEPLAPVAVTAVTGTVT
MAV_2751|M.avium_104 GCP-------GGAAPKTTGPARVRITPGPGARNVDPIAPVLVKAETGTLA
Mvan_5559|M.vanbaalenii_PYR-1 GAESAPPGPGSSAATAAARPAGLAISPTPGAVNVEPVGSVEVSALGGHLG
Mflv_2800|M.gilvum_PYR-GCK TVVAPGALEVEQTPQAAPEPPVIEILPRTGASDVVPVGAVKVTATVGTLT
. . : * .* .* *.. * :
MMAR_3872|M.marinum_M AVTMVNESGKSISGKLSSDGLHWSTDEPLGYNRRYTLNAKALGLGGAATR
MUL_3804|M.ulcerans_Agy99 AVTMVNESGKSISGKLSFDGLHWSTDEPLGYNRRYTLNAKALGLGGAATR
Mb2547c|M.bovis_AF2122/97 AVTMVNDNGRPVAGRLSPDGLRWSTTEQLGYNRRYTLNATALGLGGAATR
Rv2518c|M.tuberculosis_H37Rv AVTMVNDNGRPVAGRLSPDGLRWSTTEQLGYNRRYTLNATALGLGGAATR
MLBr_00426|M.leprae_Br4923 AVTMINDNGRMINGQFSPDGLRWSTTEPLGFNRCYTLSAKALGLGGVVNR
TH_1098|M.thermoresistible__bu AVTMVNEQGRTVEGEFSEDGVSWSTTEPLGYNRQYTITAQSLGLGGVTTR
MAB_1530|M.abscessus_ATCC_1997 SVTMVNSDGKEIAGEIGPDGVTWTTTEPLGYDKQYTINADARGLGGVARA
MSMEG_1322|M.smegmatis_MC2_155 SVRMLNDAGKEIAGALSPDGKVWKPATALGYGRTYTMNVVARGPGGMPTR
MAV_2751|M.avium_104 GVEMVNEGGTAVQGVMTPDNLVWKPTVALGYGRNYTLTITSRGTDGVETK
Mvan_5559|M.vanbaalenii_PYR-1 EVSLVNEDMEAVPGEMSADGTTWRPKVPLGYGRTYTLEAVGGG-DAAPVR
Mflv_2800|M.gilvum_PYR-GCK DVRMQNEQGRVVAGRLVEGGRAWEPAEPLGYGRSYSLSATGRGADASTVT
* : *. : * : .. * . **:.: *:: . * ..
MMAR_3872|M.marinum_M QMT-FQTSSPAHLTMPYVSPA------DGEVVGVGEPVAIRFDENIANRL
MUL_3804|M.ulcerans_Agy99 QMT-FQTSSPAHLTMPYVSPA------DGEVVGVGEPVAIRFDENIANRL
Mb2547c|M.bovis_AF2122/97 QLT-FQTSSPAHLTMPYVMPG------DGEVVGVGEPVAIRFDENIADRG
Rv2518c|M.tuberculosis_H37Rv QLT-FQTSSPAHLTMPYVMPG------DGEVVGVGEPVAIRFDENIADRG
MLBr_00426|M.leprae_Br4923 QMT-FQTSSPAHLTMPYVNPG------NGEIVGIGEPVAIRFDENIANRL
TH_1098|M.thermoresistible__bu EMT-FETHSPANLTMPYVVPS------PGEVVGVGQPVAVRFDENIPNRA
MAB_1530|M.abscessus_ATCC_1997 NAT-FRTQSPDNMTMPYVMPG------DGEVVGVGQTVAIRFDENIPNRA
MSMEG_1322|M.smegmatis_MC2_155 ASSTFTTVTPTYQANVYLNGTSGAPLKDGETYGVGMVIVARFDQAITDKA
MAV_2751|M.avium_104 QVSTFSTLRPSNQTKVSFTTTSESPLRDGASYGVGTVIVAHFDEQIADRA
Mvan_5559|M.vanbaalenii_PYR-1 AATTFTTVVPRQQAAVSLTTTSGAMLRDGAVYGVGVVVVASFDRDVPDRA
Mflv_2800|M.gilvum_PYR-GCK TVSEFSTVAPQSQVGVRLGMTNGASLSEGGVYGVGTVIVATFDADIPDRA
: * * * . . * *:* :. ** :.::
MMAR_3872|M.marinum_M AAEKAIKITTKPAVEGAFYWLNNREVRWRPEHFWKSGTSVDVAVNTYGVD
MUL_3804|M.ulcerans_Agy99 AAEKAIKITTKPAVEGAFYWLNNREVRWRPEHFWKSGTSVDVAVNTYGVD
Mb2547c|M.bovis_AF2122/97 AAEKAIKITTNPPVEGAFYWLNNREVRWRPEHFWKPGTAVDVAVNTYGVD
Rv2518c|M.tuberculosis_H37Rv AAEKAIKITTNPPVEGAFYWLNNREVRWRPEHFWKPGTAVDVAVNTYGVD
MLBr_00426|M.leprae_Br4923 AAQKAITITANPPVEGAFYWLNNREVRWRPEHFWKSGTAVDVAVNTYGVD
TH_1098|M.thermoresistible__bu AAERAIKVTTNPPVEGAFYWLNNREVRWRPASYWKPGTTVEVEVNTYGVD
MAB_1530|M.abscessus_ATCC_1997 AAEKAIKITTNPPVEGAFYWLNNREVRWRPESFWDSGTSVDVKVNTYGVN
MSMEG_1322|M.smegmatis_MC2_155 SAERRMKVTTSPKAVGSWNWIDDQTAHWRPREYYAPGTKVTVDADIYGAR
MAV_2751|M.avium_104 AAERHLTVTTNPKVTGSWFWVDGQNAHWRPEHYYAPGTTVTAEAKIYGIA
Mvan_5559|M.vanbaalenii_PYR-1 PAERALTVDTDPRVEGSWYWLDDHTAHWRPRQYHAPGTTVKVSADVYGIP
Mflv_2800|M.gilvum_PYR-GCK AAESRLQVITTPQLAGSWMWINDRKAHWRPREYFPSGTEVTVKADLYGTD
.*: : : : * *:: *::.: .:*** : .** * . .. **
MMAR_3872|M.marinum_M LGEGMFGEDNVKTHFTIGDEVIATADDNTKMLTIRVNGEVVKTMPTSMGK
MUL_3804|M.ulcerans_Agy99 LGEGMFGEDNVKTHFTIGDEVIATADDNTKMLTILVNGEVVKTMPTSMGK
Mb2547c|M.bovis_AF2122/97 LGEGMFGEDNVQTHFTIGDEVIATADDNTKILTVRVNGEVVKSMPTSMGK
Rv2518c|M.tuberculosis_H37Rv LGEGMFGEDNVQTHFTIGDEVIATADDNTKILTVRVNGEVVKSMPTSMGK
MLBr_00426|M.leprae_Br4923 LGEGMFGEDNVKTHFTIGDEVFATADDATKMLTVRVNGEVVKIMPTSMGK
TH_1098|M.thermoresistible__bu LGDGLFGQRNTKTHFTIGDEVISTVDDNTKTLTVRRNGEVVKTMPVSMGK
MAB_1530|M.abscessus_ATCC_1997 LGDGVFGQDNVASHFTIGDAVISRVDDTNKILNIERNGEIIKTMPTSMGK
MSMEG_1322|M.smegmatis_MC2_155 LGEDLYGAQDEKVSFVIGDSHVSIADDNTKQVSVYENGKLVRTMPTSMGM
MAV_2751|M.avium_104 LGDGLFGQDDSRVSFRIGDAHVSIADDATHQVSVFDNGVLVRTMPTSMGM
Mvan_5559|M.vanbaalenii_PYR-1 LGDGVYGAEDQHVRFRIGDSHVSIADDDTKQIQVYENGRLVRTMPTSMGK
Mflv_2800|M.gilvum_PYR-GCK LGSGLFGEQDKQVSFRIGPSRVAIADDTTKQVSVYENGKLIRTMPTSMGR
**..::* : * ** .: .** .: : : ** ::: **.***
MMAR_3872|M.marinum_M DSTPTANG----------IYIVGARFKHIIMDSSTYGVPVNSPNGYRTDV
MUL_3804|M.ulcerans_Agy99 DSTPTANG----------IYIVGARFKHIIMDSSTYGVPVNSPNGYRTDV
Mb2547c|M.bovis_AF2122/97 DSTPTANG----------IYIVGSRYKHIIMDSSTYGVPVNSPNGYRTDV
Rv2518c|M.tuberculosis_H37Rv DSTPTANG----------IYIVGSRYKHIIMDSSTYGVPVNSPNGYRTDV
MLBr_00426|M.leprae_Br4923 DSTPTANG----------IYIVGARFKHIIMDSSTYGVPVNSPNGYRADV
TH_1098|M.thermoresistible__bu DSTPTNNG----------VYIVGDKRAHMVMDSSTYGVPVNSPNGYRTEV
MAB_1530|M.abscessus_ATCC_1997 DKAPTNNG----------TYIIGERFKDLIMDSSTYGVAVNSPDGYRTKV
MSMEG_1322|M.smegmatis_MC2_155 GGTETVNGVTLSFWTPRGIYTVMDKANPVVMDSSTYGLPVGSRLGYRTTI
MAV_2751|M.avium_104 GGTENIGGRSISLWTPPGVYTVLDKGNPVVMDSSTFGLPKNSRLGYRETI
Mvan_5559|M.vanbaalenii_PYR-1 GGTQTIGGTTLAFWTQRGVYTVMDKSDQVVMDSSTYGLPLD--VGYRLTV
Mflv_2800|M.gilvum_PYR-GCK GGTQTVGGKTIAFWTQPGVYTVMEKQNPVLMDSSTYGLPVDSASGYKISV
. : . .* * : : ::*****:*:. . **: :
MMAR_3872|M.marinum_M NWATQLSYSGVYVHSAPWSVGAQGHTNTSHGCLNVSPSNAEWFYDHIKTG
MUL_3804|M.ulcerans_Agy99 NWATQLSYSGVYVHSAPWSVGAQGHTNTSHGCLNVSPSNAEWFYDHIKTG
Mb2547c|M.bovis_AF2122/97 DWATQISYSGVFVHSAPWSVGAQGHTNTSHGCLNVSPSNAQWFYDHVKRG
Rv2518c|M.tuberculosis_H37Rv DWATQISYSGVFVHSAPWSVGAQGHTNTSHGCLNVSPSNAQWFYDHVKRG
MLBr_00426|M.leprae_Br4923 DWATQLSYSGVFLHSAPWSVGAQGHTNTSHGCLNVSPSNAQWFYDHVKRG
TH_1098|M.thermoresistible__bu DWAVQMSYSGIYVHSAPWSVGSQGYSNVSHGCINVSPSNAKWFYENSKRG
MAB_1530|M.abscessus_ATCC_1997 QYATQMSYSGIYVHAAPWSVGAQGRTNTSHGCLNVSTANAKWFYENTKRG
MSMEG_1322|M.smegmatis_MC2_155 PYATRISVDGIYLHQLNDTIWAQGNTNVSHGCLNLSGENAQWFYNFSRPG
MAV_2751|M.avium_104 NYATKISSDGIYLHELDATVWAQGHQDTSHGCLNLNADNAKWFYDFSVPG
Mvan_5559|M.vanbaalenii_PYR-1 NNAVRLSHNGIYLHQLDSTVWAQGNTNVSHGCLNLNADHARWFYEFSRPG
Mflv_2800|M.gilvum_PYR-GCK PHAVRISPDGIYLHEREATVWAQGNTNVSAGCLNLSAEDAEWYYNFANPG
*.::* .*:::* :: :** :.* **:*:. .*.*:*: *
MMAR_3872|M.marinum_M DIVEVVNTVGGTLPGTEGLGDWNIPWEQWRAGNANA--
MUL_3804|M.ulcerans_Agy99 DIVEVVNTVGGTLPGTEGLGDWNIPWEQWRAGNANA--
Mb2547c|M.bovis_AF2122/97 DIVEVVNTVGGTLPGIDGLGDWNIPWDQWRAGNAKA--
Rv2518c|M.tuberculosis_H37Rv DIVEVVNTVGGTLPGIDGLGDWNIPWDQWRAGNAKA--
MLBr_00426|M.leprae_Br4923 DIVEVVNTVGDTLPGAEGLGDWNIPWEQWKAGNANI--
TH_1098|M.thermoresistible__bu DIIEVVNTVGTVLPGTDGLGDWNIPWEQWKAGNANV--
MAB_1530|M.abscessus_ATCC_1997 DVVIVSNTVGPVLPGTEGLGDWNIPWAQWKAGNARQQ-
MSMEG_1322|M.smegmatis_MC2_155 DIVEIRNTGGEPLKPDN-NGDWTIPWEQWRKGSALN--
MAV_2751|M.avium_104 DVVEVRNSGGPPLTLAQ-NGDWTLSWDQWRRGSALKPT
Mvan_5559|M.vanbaalenii_PYR-1 DVVEVRNTGGDPLPLWQ-NGDWSVSWDRWLQGSALS--
Mflv_2800|M.gilvum_PYR-GCK DVVEIRNTGGAPLEQWQ-NGDWSVPWDEWMGGSALRP-
*:: : *: * * : ***.:.* .* *.*