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IRPRRSLFRSAVVAMVPALLFGLMACGKDEQDGPAPVIADKGTPFGDLLVPRVNASVTDGAVGVTVESPV TVTAENGVLGGVSMTDESGSPVAGTLSPDGLTWSTTDPLDYNEQYTLVAQSLGLGGVTNRRIQFETHSPQ NLTMPYVLPNNGEVVGVGQPIAIRFDENISDRVAAQRAITVKTTPPVEGAFYWLNNREVRWRPAEYWKPG TTVDVQVNTYGVELGDGLYGQDNVETHFKIGDEVIAVADDNTKTLTVRRNGEVVKTMPISMGKNSTPTNN GVYIIGDRYEHLVMDSSTYGVPVNSPNGYRTEVDYATQMSYSGIYVHGAPWSVGSQGYSNVSHGCLNVST ANARWFYENTKRGDIVEVRNTVGSLLPGTDGLGDWNIPWEQWRAGNASI*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. smegmatis MC2 155 | MSMEG_4745 | - | - | 100% (400) | ErfK/YbiS/YcfS/YnhG family protein |
| M. smegmatis MC2 155 | MSMEG_1322 | - | 7e-81 | 42.18% (377) | ErfK/YbiS/YcfS/YnhG family protein |
| M. smegmatis MC2 155 | MSMEG_0233 | - | 5e-60 | 43.67% (245) | lipoprotein Lpps |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb2547c | lppS | 1e-171 | 71.02% (383) | lipoprotein LppS |
| M. gilvum PYR-GCK | Mflv_2542 | - | 0.0 | 75.90% (390) | ErfK/YbiS/YcfS/YnhG family protein |
| M. tuberculosis H37Rv | Rv2518c | lppS | 1e-171 | 71.02% (383) | lipoprotein LppS |
| M. leprae Br4923 | MLBr_00426 | lppS | 1e-164 | 65.33% (398) | putative secreted protein |
| M. abscessus ATCC 19977 | MAB_1530 | - | 1e-155 | 64.86% (387) | lipoprotein LppS |
| M. marinum M | MMAR_3872 | lppS | 1e-162 | 66.08% (395) | lipoprotein LppS |
| M. avium 104 | MAV_1661 | - | 1e-165 | 69.23% (377) | ErfK/YbiS/YcfS/YnhG family protein |
| M. thermoresistible (build 8) | TH_1098 | lppS | 1e-180 | 73.37% (398) | PROBABLE CONSERVED LIPOPROTEIN LPPS |
| M. ulcerans Agy99 | MUL_3804 | lppS | 1e-161 | 65.82% (395) | lipoprotein LppS |
| M. vanbaalenii PYR-1 | Mvan_4102 | - | 0.0 | 76.38% (398) | ErfK/YbiS/YcfS/YnhG family protein |
CLUSTAL 2.0.9 multiple sequence alignment
Mflv_2542|M.gilvum_PYR-GCK MGWVESAGRARWRT--SGAVAAALVGAMVFGLTGCG-GSTEAPTPQVISD
Mvan_4102|M.vanbaalenii_PYR-1 MWQVNTATRARRRR--SWLTVAVLVPAIALGLTACG-DNAEPPQAQVITD
MSMEG_4745|M.smegmatis_MC2_155 ------MIRPRRSL--FRSAVVAMVPALLFGLMACG-KDEQDGPAPVIAD
TH_1098|M.thermoresistible__bu ------MTRPRWRS--RWWLITGLLSVVVLALSACS-GGGASDQPKVITD
MLBr_00426|M.leprae_Br4923 ---MGTATRRVQPKAWRALLTLLVISVVMP-GVACN-RGGGNVPVNVIGD
MAV_1661|M.avium_104 ----------------------------MG-AVACG-GGHTAAPPKVIFD
Mb2547c|M.bovis_AF2122/97 MPKVGIAAQAGRTRVRRAWLTALMMTAVMIGAVACG-SGRGPAPIKVIAD
Rv2518c|M.tuberculosis_H37Rv MPKVGIAAQAGRTRVRRAWLTALMMTAVMIGAVACG-SGRGPAPIKVIAD
MMAR_3872|M.marinum_M ---MAPLSRR------RSWLAAILIPVAVL-AVACGGSSATPTATKVIEN
MUL_3804|M.ulcerans_Agy99 --MMAPLSRR------RSWLAAILIPVAVL-AVACGGSSATPTATKVIEN
MAB_1530|M.abscessus_ATCC_1997 ----MTQGRPRLHAGARRRWVATLALPVVAMAVLAGCAGATTQEPPKVID
.. . : :
Mflv_2542|M.gilvum_PYR-GCK KGTPFGDLLVPKLNASVQDGAVGVSAGSPVTVSAEDGVLGAVSMVNENGK
Mvan_4102|M.vanbaalenii_PYR-1 KGTPFGDLLVPKLTASVQDGAVGVSVDSPVTVSADYGVLGAVTMVNEDGE
MSMEG_4745|M.smegmatis_MC2_155 KGTPFGDLLVPRVNASVTDGAVGVTVESPVTVTAENGVLGGVSMTDESGS
TH_1098|M.thermoresistible__bu KGTPYGDLLVPRVTASVTDKAVGVPVDEPVTVSAENGVLGAVTMVNEQGR
MLBr_00426|M.leprae_Br4923 KGTPFADLLVPKLTASVTDGAVGVNVDMPVTVTVADGVLAAVTMINDNGR
MAV_1661|M.avium_104 KGTPFADLLVPKLTASVSDGAVGVTVDAPVTVSVADGVLASVTMVNENGR
Mb2547c|M.bovis_AF2122/97 KGTPFADLLVPKLTASVTDGAVGVTVDAPVSVTAADGVLAAVTMVNDNGR
Rv2518c|M.tuberculosis_H37Rv KGTPFADLLVPKLTASVTDGAVGVTVDAPVSVTAADGVLAAVTMVNDNGR
MMAR_3872|M.marinum_M KGTPFADLLVPKLTASVTDGAVGVTVDAPVTVSVSDGVLAAVTMVNESGK
MUL_3804|M.ulcerans_Agy99 KGTPFADLLVPKLTASVTDGAVGVTVDAPVTVSVSDGVLAAVTMVNESGK
MAB_1530|M.abscessus_ATCC_1997 KATPYADLLVPKLAMSVKDGAVGVAVDAPVTVTAGEGVLGSVTMVNSDGK
*.**:.*****:: ** * **** . **:*:. ***..*:* :..*
Mflv_2542|M.gilvum_PYR-GCK AVEGELTEDGLTWETAEPLGYNKRYTLTAQALGLGGVTSRQMTFETHSPE
Mvan_4102|M.vanbaalenii_PYR-1 PVAGQLSEDGLTWETAEPLGYNKSYTLTAQSLGLGGVTSSQMTFETHSPE
MSMEG_4745|M.smegmatis_MC2_155 PVAGTLSPDGLTWSTTDPLDYNEQYTLVAQSLGLGGVTNRRIQFETHSPQ
TH_1098|M.thermoresistible__bu TVEGEFSEDGVSWSTTEPLGYNRQYTITAQSLGLGGVTTREMTFETHSPA
MLBr_00426|M.leprae_Br4923 MINGQFSPDGLRWSTTEPLGFNRCYTLSAKALGLGGVVNRQMTFQTSSPA
MAV_1661|M.avium_104 SISGQLSPDGLRWSTTEQLGYNRRYTLTAKATGLGGAASKQMTFETSSPA
Mb2547c|M.bovis_AF2122/97 PVAGRLSPDGLRWSTTEQLGYNRRYTLNATALGLGGAATRQLTFQTSSPA
Rv2518c|M.tuberculosis_H37Rv PVAGRLSPDGLRWSTTEQLGYNRRYTLNATALGLGGAATRQLTFQTSSPA
MMAR_3872|M.marinum_M SISGKLSSDGLHWSTDEPLGYNRRYTLNAKALGLGGAATRQMTFQTSSPA
MUL_3804|M.ulcerans_Agy99 SISGKLSFDGLHWSTDEPLGYNRRYTLNAKALGLGGAATRQMTFQTSSPA
MAB_1530|M.abscessus_ATCC_1997 EIAGEIGPDGVTWTTTEPLGYDKQYTINADARGLGGVARANATFRTQSPD
: * : **: * * : *.::. **: * : ****.. . *.* **
Mflv_2542|M.gilvum_PYR-GCK NLTMPYVLPNDGEVVGVGQPVAIRFDENIPNRLAAQRAITVKTTPEVEGA
Mvan_4102|M.vanbaalenii_PYR-1 NLTMPYVLPNDGEVVGVGQPVAIQFDENIPNRLAAQRAITVKTTPPVEGA
MSMEG_4745|M.smegmatis_MC2_155 NLTMPYVLPNNGEVVGVGQPIAIRFDENISDRVAAQRAITVKTTPPVEGA
TH_1098|M.thermoresistible__bu NLTMPYVVPSPGEVVGVGQPVAVRFDENIPNRAAAERAIKVTTNPPVEGA
MLBr_00426|M.leprae_Br4923 HLTMPYVNPGNGEIVGIGEPVAIRFDENIANRLAAQKAITITANPPVEGA
MAV_1661|M.avium_104 HLTMPYVSPADGEVVGVGEPVAIRFDENIANRAAAQKAITITTNPPVEGA
Mb2547c|M.bovis_AF2122/97 HLTMPYVMPGDGEVVGVGEPVAIRFDENIADRGAAEKAIKITTNPPVEGA
Rv2518c|M.tuberculosis_H37Rv HLTMPYVMPGDGEVVGVGEPVAIRFDENIADRGAAEKAIKITTNPPVEGA
MMAR_3872|M.marinum_M HLTMPYVSPADGEVVGVGEPVAIRFDENIANRLAAEKAIKITTKPAVEGA
MUL_3804|M.ulcerans_Agy99 HLTMPYVSPADGEVVGVGEPVAIRFDENIANRLAAEKAIKITTKPAVEGA
MAB_1530|M.abscessus_ATCC_1997 NMTMPYVMPGDGEVVGVGQTVAIRFDENIPNRAAAEKAIKITTNPPVEGA
::***** * **:**:*:.:*::*****.:* **::**.:.:.* ****
Mflv_2542|M.gilvum_PYR-GCK FYWLNNREVRWRPAKYWKPGTTVEVEVNTYGVDLGDGLFGQDNVSTSFTI
Mvan_4102|M.vanbaalenii_PYR-1 FYWLNNREVRWRPAKYWKPGTTVEVAVNTYGVDLGDGLFGQDNVKTSFKI
MSMEG_4745|M.smegmatis_MC2_155 FYWLNNREVRWRPAEYWKPGTTVDVQVNTYGVELGDGLYGQDNVETHFKI
TH_1098|M.thermoresistible__bu FYWLNNREVRWRPASYWKPGTTVEVEVNTYGVDLGDGLFGQRNTKTHFTI
MLBr_00426|M.leprae_Br4923 FYWLNNREVRWRPEHFWKSGTAVDVAVNTYGVDLGEGMFGEDNVKTHFTI
MAV_1661|M.avium_104 FYWLNNREVRWRPEHFWKSGTVIDVAVNTYGVDLGDGMFGEDNVKTHFTI
Mb2547c|M.bovis_AF2122/97 FYWLNNREVRWRPEHFWKPGTAVDVAVNTYGVDLGEGMFGEDNVQTHFTI
Rv2518c|M.tuberculosis_H37Rv FYWLNNREVRWRPEHFWKPGTAVDVAVNTYGVDLGEGMFGEDNVQTHFTI
MMAR_3872|M.marinum_M FYWLNNREVRWRPEHFWKSGTSVDVAVNTYGVDLGEGMFGEDNVKTHFTI
MUL_3804|M.ulcerans_Agy99 FYWLNNREVRWRPEHFWKSGTSVDVAVNTYGVDLGEGMFGEDNVKTHFTI
MAB_1530|M.abscessus_ATCC_1997 FYWLNNREVRWRPESFWDSGTSVDVKVNTYGVNLGDGVFGQDNVASHFTI
************* :*..** ::* ******:**:*::*: *. : *.*
Mflv_2542|M.gilvum_PYR-GCK GDQMVTTVDDSTKTLTVRRNGEVVKTMPVSMGKNSTPTNNGVYIVGDRRS
Mvan_4102|M.vanbaalenii_PYR-1 GDEVITTVDDNTKTLTVRRNGEVIKSMPVSMGKNSTPTNNGVYIVGDRRS
MSMEG_4745|M.smegmatis_MC2_155 GDEVIAVADDNTKTLTVRRNGEVVKTMPISMGKNSTPTNNGVYIIGDRYE
TH_1098|M.thermoresistible__bu GDEVISTVDDNTKTLTVRRNGEVVKTMPVSMGKDSTPTNNGVYIVGDKRA
MLBr_00426|M.leprae_Br4923 GDEVFATADDATKMLTVRVNGEVVKIMPTSMGKDSTPTANGIYIVGARFK
MAV_1661|M.avium_104 GDEVISTADDTTKTVTVRVNGEVVKTMPTSMGKDSTPTANGIYIVGARFK
Mb2547c|M.bovis_AF2122/97 GDEVIATADDNTKILTVRVNGEVVKSMPTSMGKDSTPTANGIYIVGSRYK
Rv2518c|M.tuberculosis_H37Rv GDEVIATADDNTKILTVRVNGEVVKSMPTSMGKDSTPTANGIYIVGSRYK
MMAR_3872|M.marinum_M GDEVIATADDNTKMLTIRVNGEVVKTMPTSMGKDSTPTANGIYIVGARFK
MUL_3804|M.ulcerans_Agy99 GDEVIATADDNTKMLTILVNGEVVKTMPTSMGKDSTPTANGIYIVGARFK
MAB_1530|M.abscessus_ATCC_1997 GDAVISRVDDTNKILNIERNGEIIKTMPTSMGKDKAPTNNGTYIIGERFK
** :.: .** .* :.: ***::* ** ****:.:** ** **:* :
Mflv_2542|M.gilvum_PYR-GCK HMVMDSSTYGVPVNSANGYRTEVDWATQISYSGIYVHAAPWSVGSQGESN
Mvan_4102|M.vanbaalenii_PYR-1 HMVMDSSTYGVPANSPNGYRTEVDWATQISYSGIYVHAAPWSVGSQGYSN
MSMEG_4745|M.smegmatis_MC2_155 HLVMDSSTYGVPVNSPNGYRTEVDYATQMSYSGIYVHGAPWSVGSQGYSN
TH_1098|M.thermoresistible__bu HMVMDSSTYGVPVNSPNGYRTEVDWAVQMSYSGIYVHSAPWSVGSQGYSN
MLBr_00426|M.leprae_Br4923 HIIMDSSTYGVPVNSPNGYRADVDWATQLSYSGVFLHSAPWSVGAQGHTN
MAV_1661|M.avium_104 HIIMDSSTYGVPVNSPNGYRTEVDWATQMSYSGVFVHSAPWSVGAQGHTN
Mb2547c|M.bovis_AF2122/97 HIIMDSSTYGVPVNSPNGYRTDVDWATQISYSGVFVHSAPWSVGAQGHTN
Rv2518c|M.tuberculosis_H37Rv HIIMDSSTYGVPVNSPNGYRTDVDWATQISYSGVFVHSAPWSVGAQGHTN
MMAR_3872|M.marinum_M HIIMDSSTYGVPVNSPNGYRTDVNWATQLSYSGVYVHSAPWSVGAQGHTN
MUL_3804|M.ulcerans_Agy99 HIIMDSSTYGVPVNSPNGYRTDVNWATQLSYSGVYVHSAPWSVGAQGHTN
MAB_1530|M.abscessus_ATCC_1997 DLIMDSSTYGVAVNSPDGYRTKVQYATQMSYSGIYVHAAPWSVGAQGRTN
.::********..**.:***:.*::*.*:****:::*.******:** :*
Mflv_2542|M.gilvum_PYR-GCK VSHGCINVSTSNGKWFYDNSKRGDIVEIVNTVGSPLPGTDGLGDWNIPWE
Mvan_4102|M.vanbaalenii_PYR-1 VSHGCINVSTSNGQWFYDNSKRGDIVEIVNTVGSPLSGTDGLGDWNIPWD
MSMEG_4745|M.smegmatis_MC2_155 VSHGCLNVSTANARWFYENTKRGDIVEVRNTVGSLLPGTDGLGDWNIPWE
TH_1098|M.thermoresistible__bu VSHGCINVSPSNAKWFYENSKRGDIIEVVNTVGTVLPGTDGLGDWNIPWE
MLBr_00426|M.leprae_Br4923 TSHGCLNVSPSNAQWFYDHVKRGDIVEVVNTVGDTLPGAEGLGDWNIPWE
MAV_1661|M.avium_104 TSHGCLNVSPSNAEWFYDHSKSGDIVEVVHTVGPTLPGTEGLGDWNIPWS
Mb2547c|M.bovis_AF2122/97 TSHGCLNVSPSNAQWFYDHVKRGDIVEVVNTVGGTLPGIDGLGDWNIPWD
Rv2518c|M.tuberculosis_H37Rv TSHGCLNVSPSNAQWFYDHVKRGDIVEVVNTVGGTLPGIDGLGDWNIPWD
MMAR_3872|M.marinum_M TSHGCLNVSPSNAEWFYDHIKTGDIVEVVNTVGGTLPGTEGLGDWNIPWE
MUL_3804|M.ulcerans_Agy99 TSHGCLNVSPSNAEWFYDHIKTGDIVEVVNTVGGTLPGTEGLGDWNIPWE
MAB_1530|M.abscessus_ATCC_1997 TSHGCLNVSTANAKWFYENTKRGDVVIVSNTVGPVLPGTEGLGDWNIPWA
.****:***.:*..***:: * **:: : :*** *.* :*********
Mflv_2542|M.gilvum_PYR-GCK QWKAGNANL-
Mvan_4102|M.vanbaalenii_PYR-1 QWKAGNANL-
MSMEG_4745|M.smegmatis_MC2_155 QWRAGNASI-
TH_1098|M.thermoresistible__bu QWKAGNANV-
MLBr_00426|M.leprae_Br4923 QWKAGNANI-
MAV_1661|M.avium_104 QWKAGNANT-
Mb2547c|M.bovis_AF2122/97 QWRAGNAKA-
Rv2518c|M.tuberculosis_H37Rv QWRAGNAKA-
MMAR_3872|M.marinum_M QWRAGNANA-
MUL_3804|M.ulcerans_Agy99 QWRAGNANA-
MAB_1530|M.abscessus_ATCC_1997 QWKAGNARQQ
**:****