For questions or suggestions e-mail us at: ioerger@cs.tamu.edu
ELGRWRGTARLATALAHLALLGAAVVGVLSIDGGAESAPPGPGSSAATAAARPAGLAISPTPGAVNVEPV GSVEVSALGGHLGEVSLVNEDMEAVPGEMSADGTTWRPKVPLGYGRTYTLEAVGGGDAAPVRAATTFTTV VPRQQAAVSLTTTSGAMLRDGAVYGVGVVVVASFDRDVPDRAPAERALTVDTDPRVEGSWYWLDDHTAHW RPRQYHAPGTTVKVSADVYGIPLGDGVYGAEDQHVRFRIGDSHVSIADDDTKQIQVYENGRLVRTMPTSM GKGGTQTIGGTTLAFWTQRGVYTVMDKSDQVVMDSSTYGLPLDVGYRLTVNNAVRLSHNGIYLHQLDSTV WAQGNTNVSHGCLNLNADHARWFYEFSRPGDVVEVRNTGGDPLPLWQNGDWSVSWDRWLQGSALS*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. vanbaalenii PYR-1 | Mvan_5559 | - | - | 100% (416) | ErfK/YbiS/YcfS/YnhG family protein |
| M. vanbaalenii PYR-1 | Mvan_3723 | - | e-129 | 59.62% (369) | ErfK/YbiS/YcfS/YnhG family protein |
| M. vanbaalenii PYR-1 | Mvan_4102 | - | 1e-81 | 40.69% (403) | ErfK/YbiS/YcfS/YnhG family protein |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb2547c | lppS | 7e-77 | 38.11% (412) | lipoprotein LppS |
| M. gilvum PYR-GCK | Mflv_2800 | - | 1e-128 | 58.54% (369) | ErfK/YbiS/YcfS/YnhG family protein |
| M. tuberculosis H37Rv | Rv2518c | lppS | 7e-77 | 38.11% (412) | lipoprotein LppS |
| M. leprae Br4923 | MLBr_00426 | lppS | 3e-72 | 38.78% (361) | putative secreted protein |
| M. abscessus ATCC 19977 | MAB_1530 | - | 2e-76 | 39.70% (403) | lipoprotein LppS |
| M. marinum M | MMAR_3872 | lppS | 5e-77 | 39.65% (396) | lipoprotein LppS |
| M. avium 104 | MAV_2751 | - | 1e-130 | 55.29% (416) | ErfK/YbiS/YcfS/YnhG family protein |
| M. smegmatis MC2 155 | MSMEG_1322 | - | 1e-135 | 55.83% (412) | ErfK/YbiS/YcfS/YnhG family protein |
| M. thermoresistible (build 8) | TH_1098 | lppS | 2e-81 | 41.29% (419) | PROBABLE CONSERVED LIPOPROTEIN LPPS |
| M. ulcerans Agy99 | MUL_3804 | lppS | 6e-77 | 39.65% (396) | lipoprotein LppS |
CLUSTAL 2.0.9 multiple sequence alignment
MMAR_3872|M.marinum_M ---MAPLS-----------RR------RSWLAAILIPVAVLAVACGGSSA
MUL_3804|M.ulcerans_Agy99 --MMAPLS-----------RR------RSWLAAILIPVAVLAVACGGSSA
Mb2547c|M.bovis_AF2122/97 MPKVGIAA-----------QAGRTRVRRAWLTALMMTAVMIGAVACGSGR
Rv2518c|M.tuberculosis_H37Rv MPKVGIAA-----------QAGRTRVRRAWLTALMMTAVMIGAVACGSGR
MLBr_00426|M.leprae_Br4923 ---MGTAT-----------RRVQPKAWRALLTLLVISVVMPG-VACNRGG
TH_1098|M.thermoresistible__bu ---MTRPR-----------WRS-----RWWLITGLLSVVVLALSACSGGG
MAB_1530|M.abscessus_ATCC_1997 ---MTQGR-----------PRLHAGARRRWVATLALPVVAMAVLAGCAGA
MAV_2751|M.avium_104 ---MASKSSDRLVGRILGVRRPRRFLAAVFVVVAVAGAIQLAEAAPCPHG
MSMEG_1322|M.smegmatis_MC2_155 ---MMLSS----------VRR--ACLAAVLAVLAVLGGVVVTALPDCVHE
Mvan_5559|M.vanbaalenii_PYR-1 ---MELGR-----------WRGTARLATALAHLALLGAAVVGVLS--IDG
Mflv_2800|M.gilvum_PYR-GCK ---MLAGR------------RKVVALSVISAVAVLVTASQTSALKSRLTN
:
MMAR_3872|M.marinum_M TPTATKVIENKGTPFADLLVPKLTASVTDGAVGVTVDAPVTVSVSDGVLA
MUL_3804|M.ulcerans_Agy99 TPTATKVIENKGTPFADLLVPKLTASVTDGAVGVTVDAPVTVSVSDGVLA
Mb2547c|M.bovis_AF2122/97 GPAPIKVIADKGTPFADLLVPKLTASVTDGAVGVTVDAPVSVTAADGVLA
Rv2518c|M.tuberculosis_H37Rv GPAPIKVIADKGTPFADLLVPKLTASVTDGAVGVTVDAPVSVTAADGVLA
MLBr_00426|M.leprae_Br4923 GNVPVNVIGDKGTPFADLLVPKLTASVTDGAVGVNVDMPVTVTVADGVLA
TH_1098|M.thermoresistible__bu ASDQPKVITDKGTPYGDLLVPRVTASVTDKAVGVPVDEPVTVSAENGVLG
MAB_1530|M.abscessus_ATCC_1997 TTQEPPKVIDKATPYADLLVPKLAMSVKDGAVGVAVDAPVTVTAGEGVLG
MAV_2751|M.avium_104 GCP-------GGAAPKTTGPARVRITPGPGARNVDPIAPVLVKAETGTLA
MSMEG_1322|M.smegmatis_MC2_155 HCQTMAAAPQGVPQPSPTEPAKLTITPKNNAEDVEPLAPVAVTAVTGTVT
Mvan_5559|M.vanbaalenii_PYR-1 GAESAPPGPGSSAATAAARPAGLAISPTPGAVNVEPVGSVEVSALGGHLG
Mflv_2800|M.gilvum_PYR-GCK TVVAPGALEVEQTPQAAPEPPVIEILPRTGASDVVPVGAVKVTATVGTLT
. . : * .* .* *.. * :
MMAR_3872|M.marinum_M AVTMVNESGKSISGKLSSDGLHWSTDEPLGYNRRYTLNAKALGLGGAATR
MUL_3804|M.ulcerans_Agy99 AVTMVNESGKSISGKLSFDGLHWSTDEPLGYNRRYTLNAKALGLGGAATR
Mb2547c|M.bovis_AF2122/97 AVTMVNDNGRPVAGRLSPDGLRWSTTEQLGYNRRYTLNATALGLGGAATR
Rv2518c|M.tuberculosis_H37Rv AVTMVNDNGRPVAGRLSPDGLRWSTTEQLGYNRRYTLNATALGLGGAATR
MLBr_00426|M.leprae_Br4923 AVTMINDNGRMINGQFSPDGLRWSTTEPLGFNRCYTLSAKALGLGGVVNR
TH_1098|M.thermoresistible__bu AVTMVNEQGRTVEGEFSEDGVSWSTTEPLGYNRQYTITAQSLGLGGVTTR
MAB_1530|M.abscessus_ATCC_1997 SVTMVNSDGKEIAGEIGPDGVTWTTTEPLGYDKQYTINADARGLGGVARA
MAV_2751|M.avium_104 GVEMVNEGGTAVQGVMTPDNLVWKPTVALGYGRNYTLTITSRGTDGVETK
MSMEG_1322|M.smegmatis_MC2_155 SVRMLNDAGKEIAGALSPDGKVWKPATALGYGRTYTMNVVARGPGGMPTR
Mvan_5559|M.vanbaalenii_PYR-1 EVSLVNEDMEAVPGEMSADGTTWRPKVPLGYGRTYTLEAVGGG-DAAPVR
Mflv_2800|M.gilvum_PYR-GCK DVRMQNEQGRVVAGRLVEGGRAWEPAEPLGYGRSYSLSATGRGADASTVT
* : *. : * : .. * . **:.: *:: . * ..
MMAR_3872|M.marinum_M QMT-FQTSSPAHLTMPYVSPA------DGEVVGVGEPVAIRFDENIANRL
MUL_3804|M.ulcerans_Agy99 QMT-FQTSSPAHLTMPYVSPA------DGEVVGVGEPVAIRFDENIANRL
Mb2547c|M.bovis_AF2122/97 QLT-FQTSSPAHLTMPYVMPG------DGEVVGVGEPVAIRFDENIADRG
Rv2518c|M.tuberculosis_H37Rv QLT-FQTSSPAHLTMPYVMPG------DGEVVGVGEPVAIRFDENIADRG
MLBr_00426|M.leprae_Br4923 QMT-FQTSSPAHLTMPYVNPG------NGEIVGIGEPVAIRFDENIANRL
TH_1098|M.thermoresistible__bu EMT-FETHSPANLTMPYVVPS------PGEVVGVGQPVAVRFDENIPNRA
MAB_1530|M.abscessus_ATCC_1997 NAT-FRTQSPDNMTMPYVMPG------DGEVVGVGQTVAIRFDENIPNRA
MAV_2751|M.avium_104 QVSTFSTLRPSNQTKVSFTTTSESPLRDGASYGVGTVIVAHFDEQIADRA
MSMEG_1322|M.smegmatis_MC2_155 ASSTFTTVTPTYQANVYLNGTSGAPLKDGETYGVGMVIVARFDQAITDKA
Mvan_5559|M.vanbaalenii_PYR-1 AATTFTTVVPRQQAAVSLTTTSGAMLRDGAVYGVGVVVVASFDRDVPDRA
Mflv_2800|M.gilvum_PYR-GCK TVSEFSTVAPQSQVGVRLGMTNGASLSEGGVYGVGTVIVATFDADIPDRA
: * * * . . * *:* :. ** :.::
MMAR_3872|M.marinum_M AAEKAIKITTKPAVEGAFYWLNNREVRWRPEHFWKSGTSVDVAVNTYGVD
MUL_3804|M.ulcerans_Agy99 AAEKAIKITTKPAVEGAFYWLNNREVRWRPEHFWKSGTSVDVAVNTYGVD
Mb2547c|M.bovis_AF2122/97 AAEKAIKITTNPPVEGAFYWLNNREVRWRPEHFWKPGTAVDVAVNTYGVD
Rv2518c|M.tuberculosis_H37Rv AAEKAIKITTNPPVEGAFYWLNNREVRWRPEHFWKPGTAVDVAVNTYGVD
MLBr_00426|M.leprae_Br4923 AAQKAITITANPPVEGAFYWLNNREVRWRPEHFWKSGTAVDVAVNTYGVD
TH_1098|M.thermoresistible__bu AAERAIKVTTNPPVEGAFYWLNNREVRWRPASYWKPGTTVEVEVNTYGVD
MAB_1530|M.abscessus_ATCC_1997 AAEKAIKITTNPPVEGAFYWLNNREVRWRPESFWDSGTSVDVKVNTYGVN
MAV_2751|M.avium_104 AAERHLTVTTNPKVTGSWFWVDGQNAHWRPEHYYAPGTTVTAEAKIYGIA
MSMEG_1322|M.smegmatis_MC2_155 SAERRMKVTTSPKAVGSWNWIDDQTAHWRPREYYAPGTKVTVDADIYGAR
Mvan_5559|M.vanbaalenii_PYR-1 PAERALTVDTDPRVEGSWYWLDDHTAHWRPRQYHAPGTTVKVSADVYGIP
Mflv_2800|M.gilvum_PYR-GCK AAESRLQVITTPQLAGSWMWINDRKAHWRPREYFPSGTEVTVKADLYGTD
.*: : : : * *:: *::.: .:*** : .** * . .. **
MMAR_3872|M.marinum_M LGEGMFGEDNVKTHFTIGDEVIATADDNTKMLTIRVNGEVVKTMPTSMGK
MUL_3804|M.ulcerans_Agy99 LGEGMFGEDNVKTHFTIGDEVIATADDNTKMLTILVNGEVVKTMPTSMGK
Mb2547c|M.bovis_AF2122/97 LGEGMFGEDNVQTHFTIGDEVIATADDNTKILTVRVNGEVVKSMPTSMGK
Rv2518c|M.tuberculosis_H37Rv LGEGMFGEDNVQTHFTIGDEVIATADDNTKILTVRVNGEVVKSMPTSMGK
MLBr_00426|M.leprae_Br4923 LGEGMFGEDNVKTHFTIGDEVFATADDATKMLTVRVNGEVVKIMPTSMGK
TH_1098|M.thermoresistible__bu LGDGLFGQRNTKTHFTIGDEVISTVDDNTKTLTVRRNGEVVKTMPVSMGK
MAB_1530|M.abscessus_ATCC_1997 LGDGVFGQDNVASHFTIGDAVISRVDDTNKILNIERNGEIIKTMPTSMGK
MAV_2751|M.avium_104 LGDGLFGQDDSRVSFRIGDAHVSIADDATHQVSVFDNGVLVRTMPTSMGM
MSMEG_1322|M.smegmatis_MC2_155 LGEDLYGAQDEKVSFVIGDSHVSIADDNTKQVSVYENGKLVRTMPTSMGM
Mvan_5559|M.vanbaalenii_PYR-1 LGDGVYGAEDQHVRFRIGDSHVSIADDDTKQIQVYENGRLVRTMPTSMGK
Mflv_2800|M.gilvum_PYR-GCK LGSGLFGEQDKQVSFRIGPSRVAIADDTTKQVSVYENGKLIRTMPTSMGR
**..::* : * ** .: .** .: : : ** ::: **.***
MMAR_3872|M.marinum_M DSTPTANG----------IYIVGARFKHIIMDSSTYGVPVNSPNGYRTDV
MUL_3804|M.ulcerans_Agy99 DSTPTANG----------IYIVGARFKHIIMDSSTYGVPVNSPNGYRTDV
Mb2547c|M.bovis_AF2122/97 DSTPTANG----------IYIVGSRYKHIIMDSSTYGVPVNSPNGYRTDV
Rv2518c|M.tuberculosis_H37Rv DSTPTANG----------IYIVGSRYKHIIMDSSTYGVPVNSPNGYRTDV
MLBr_00426|M.leprae_Br4923 DSTPTANG----------IYIVGARFKHIIMDSSTYGVPVNSPNGYRADV
TH_1098|M.thermoresistible__bu DSTPTNNG----------VYIVGDKRAHMVMDSSTYGVPVNSPNGYRTEV
MAB_1530|M.abscessus_ATCC_1997 DKAPTNNG----------TYIIGERFKDLIMDSSTYGVAVNSPDGYRTKV
MAV_2751|M.avium_104 GGTENIGGRSISLWTPPGVYTVLDKGNPVVMDSSTFGLPKNSRLGYRETI
MSMEG_1322|M.smegmatis_MC2_155 GGTETVNGVTLSFWTPRGIYTVMDKANPVVMDSSTYGLPVGSRLGYRTTI
Mvan_5559|M.vanbaalenii_PYR-1 GGTQTIGGTTLAFWTQRGVYTVMDKSDQVVMDSSTYGLPLD--VGYRLTV
Mflv_2800|M.gilvum_PYR-GCK GGTQTVGGKTIAFWTQPGVYTVMEKQNPVLMDSSTYGLPVDSASGYKISV
. : . .* * : : ::*****:*:. . **: :
MMAR_3872|M.marinum_M NWATQLSYSGVYVHSAPWSVGAQGHTNTSHGCLNVSPSNAEWFYDHIKTG
MUL_3804|M.ulcerans_Agy99 NWATQLSYSGVYVHSAPWSVGAQGHTNTSHGCLNVSPSNAEWFYDHIKTG
Mb2547c|M.bovis_AF2122/97 DWATQISYSGVFVHSAPWSVGAQGHTNTSHGCLNVSPSNAQWFYDHVKRG
Rv2518c|M.tuberculosis_H37Rv DWATQISYSGVFVHSAPWSVGAQGHTNTSHGCLNVSPSNAQWFYDHVKRG
MLBr_00426|M.leprae_Br4923 DWATQLSYSGVFLHSAPWSVGAQGHTNTSHGCLNVSPSNAQWFYDHVKRG
TH_1098|M.thermoresistible__bu DWAVQMSYSGIYVHSAPWSVGSQGYSNVSHGCINVSPSNAKWFYENSKRG
MAB_1530|M.abscessus_ATCC_1997 QYATQMSYSGIYVHAAPWSVGAQGRTNTSHGCLNVSTANAKWFYENTKRG
MAV_2751|M.avium_104 NYATKISSDGIYLHELDATVWAQGHQDTSHGCLNLNADNAKWFYDFSVPG
MSMEG_1322|M.smegmatis_MC2_155 PYATRISVDGIYLHQLNDTIWAQGNTNVSHGCLNLSGENAQWFYNFSRPG
Mvan_5559|M.vanbaalenii_PYR-1 NNAVRLSHNGIYLHQLDSTVWAQGNTNVSHGCLNLNADHARWFYEFSRPG
Mflv_2800|M.gilvum_PYR-GCK PHAVRISPDGIYLHEREATVWAQGNTNVSAGCLNLSAEDAEWYYNFANPG
*.::* .*:::* :: :** :.* **:*:. .*.*:*: *
MMAR_3872|M.marinum_M DIVEVVNTVGGTLPGTEGLGDWNIPWEQWRAGNANA--
MUL_3804|M.ulcerans_Agy99 DIVEVVNTVGGTLPGTEGLGDWNIPWEQWRAGNANA--
Mb2547c|M.bovis_AF2122/97 DIVEVVNTVGGTLPGIDGLGDWNIPWDQWRAGNAKA--
Rv2518c|M.tuberculosis_H37Rv DIVEVVNTVGGTLPGIDGLGDWNIPWDQWRAGNAKA--
MLBr_00426|M.leprae_Br4923 DIVEVVNTVGDTLPGAEGLGDWNIPWEQWKAGNANI--
TH_1098|M.thermoresistible__bu DIIEVVNTVGTVLPGTDGLGDWNIPWEQWKAGNANV--
MAB_1530|M.abscessus_ATCC_1997 DVVIVSNTVGPVLPGTEGLGDWNIPWAQWKAGNARQQ-
MAV_2751|M.avium_104 DVVEVRNSGGPPLTLAQ-NGDWTLSWDQWRRGSALKPT
MSMEG_1322|M.smegmatis_MC2_155 DIVEIRNTGGEPLKPDN-NGDWTIPWEQWRKGSALN--
Mvan_5559|M.vanbaalenii_PYR-1 DVVEVRNTGGDPLPLWQ-NGDWSVSWDRWLQGSALS--
Mflv_2800|M.gilvum_PYR-GCK DVVEIRNTGGAPLEQWQ-NGDWSVPWDEWMGGSALRP-
*:: : *: * * : ***.:.* .* *.*