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VLAGRRKVVALSVISAVAVLVTASQTSALKSRLTNTVVAPGALEVEQTPQAAPEPPVIEILPRTGASDVV PVGAVKVTATVGTLTDVRMQNEQGRVVAGRLVEGGRAWEPAEPLGYGRSYSLSATGRGADASTVTTVSEF STVAPQSQVGVRLGMTNGASLSEGGVYGVGTVIVATFDADIPDRAAAESRLQVITTPQLAGSWMWINDRK AHWRPREYFPSGTEVTVKADLYGTDLGSGLFGEQDKQVSFRIGPSRVAIADDTTKQVSVYENGKLIRTMP TSMGRGGTQTVGGKTIAFWTQPGVYTVMEKQNPVLMDSSTYGLPVDSASGYKISVPHAVRISPDGIYLHE REATVWAQGNTNVSAGCLNLSAEDAEWYYNFANPGDVVEIRNTGGAPLEQWQNGDWSVPWDEWMGGSALR P
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. gilvum PYR-GCK | Mflv_2800 | - | - | 100% (421) | ErfK/YbiS/YcfS/YnhG family protein |
| M. gilvum PYR-GCK | Mflv_2542 | - | 4e-77 | 39.90% (381) | ErfK/YbiS/YcfS/YnhG family protein |
| M. gilvum PYR-GCK | Mflv_0904 | - | 2e-72 | 36.67% (409) | ErfK/YbiS/YcfS/YnhG family protein |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb2547c | lppS | 2e-75 | 37.95% (419) | lipoprotein LppS |
| M. tuberculosis H37Rv | Rv2518c | lppS | 2e-75 | 37.95% (419) | lipoprotein LppS |
| M. leprae Br4923 | MLBr_00426 | lppS | 1e-69 | 37.10% (372) | putative secreted protein |
| M. abscessus ATCC 19977 | MAB_1530 | - | 4e-72 | 36.54% (416) | lipoprotein LppS |
| M. marinum M | MMAR_3872 | lppS | 1e-75 | 37.35% (415) | lipoprotein LppS |
| M. avium 104 | MAV_2751 | - | 1e-119 | 54.01% (374) | ErfK/YbiS/YcfS/YnhG family protein |
| M. smegmatis MC2 155 | MSMEG_1322 | - | 1e-133 | 53.90% (423) | ErfK/YbiS/YcfS/YnhG family protein |
| M. thermoresistible (build 8) | TH_1098 | lppS | 8e-74 | 40.71% (366) | PROBABLE CONSERVED LIPOPROTEIN LPPS |
| M. ulcerans Agy99 | MUL_3804 | lppS | 1e-75 | 37.35% (415) | lipoprotein LppS |
| M. vanbaalenii PYR-1 | Mvan_3723 | - | 0.0 | 92.64% (421) | ErfK/YbiS/YcfS/YnhG family protein |
CLUSTAL 2.0.9 multiple sequence alignment
MMAR_3872|M.marinum_M ---MAPL----------SRR------RSWLAAILIPVAVLAVACGGSSAT
MUL_3804|M.ulcerans_Agy99 --MMAPL----------SRR------RSWLAAILIPVAVLAVACGGSSAT
Mb2547c|M.bovis_AF2122/97 MPKVGIA----------AQAGRTRVRRAWLTALMMTAVMIGAVACGSGRG
Rv2518c|M.tuberculosis_H37Rv MPKVGIA----------AQAGRTRVRRAWLTALMMTAVMIGAVACGSGRG
MLBr_00426|M.leprae_Br4923 ---MGTA----------TRRVQPKAWRALLTLLVISVVMPG-VACNRGGG
TH_1098|M.thermoresistible__bu ---MTRP----------RWRS-----RWWLITGLLSVVVLALSACSGGGA
MAB_1530|M.abscessus_ATCC_1997 ---MTQG----------RPRLHAGARRRWVATLALPVVAMAVLAGCAGAT
Mflv_2800|M.gilvum_PYR-GCK ---MLAG-----------RRKVVALSVISAVAVLVTASQTSALKSRLTNT
Mvan_3723|M.vanbaalenii_PYR-1 ---MLTG-----------RRQVAALSVFSAVAVLVTASQTSALKSRLSNT
MAV_2751|M.avium_104 --MASKSSDRLVGRILGVRRPRRFLAAVFVVVAVAGAIQLAEAAPCPHGG
MSMEG_1322|M.smegmatis_MC2_155 --MMLSS----------VRR--ACLAAVLAVLAVLGGVVVTALPDCVHEH
MMAR_3872|M.marinum_M PTATKVIENKGTPFADLLVPKLTASVTDGAVGVTVDAPVTVSVSDGVLAA
MUL_3804|M.ulcerans_Agy99 PTATKVIENKGTPFADLLVPKLTASVTDGAVGVTVDAPVTVSVSDGVLAA
Mb2547c|M.bovis_AF2122/97 PAPIKVIADKGTPFADLLVPKLTASVTDGAVGVTVDAPVSVTAADGVLAA
Rv2518c|M.tuberculosis_H37Rv PAPIKVIADKGTPFADLLVPKLTASVTDGAVGVTVDAPVSVTAADGVLAA
MLBr_00426|M.leprae_Br4923 NVPVNVIGDKGTPFADLLVPKLTASVTDGAVGVNVDMPVTVTVADGVLAA
TH_1098|M.thermoresistible__bu SDQPKVITDKGTPYGDLLVPRVTASVTDKAVGVPVDEPVTVSAENGVLGA
MAB_1530|M.abscessus_ATCC_1997 TQEPPKVIDKATPYADLLVPKLAMSVKDGAVGVAVDAPVTVTAGEGVLGS
Mflv_2800|M.gilvum_PYR-GCK VVAPGALEVEQTPQAAPEPPVIEILPRTGASDVVPVGAVKVTATVGTLTD
Mvan_3723|M.vanbaalenii_PYR-1 VTAPGAVEVEQTPQAAPKPPVIEILPRTGASDVVPVGAVKVTATVGTLTD
MAV_2751|M.avium_104 CP-------GGAAPKTTGPARVRITPGPGARNVDPIAPVLVKAETGTLAG
MSMEG_1322|M.smegmatis_MC2_155 CQTMAAAPQGVPQPSPTEPAKLTITPKNNAEDVEPLAPVAVTAVTGTVTS
. . : * .* .* *.. *.:
MMAR_3872|M.marinum_M VTMVNESGKSISGKLSSDGLHWSTDEPLGYNRRYTLNAKALGLGGAATRQ
MUL_3804|M.ulcerans_Agy99 VTMVNESGKSISGKLSFDGLHWSTDEPLGYNRRYTLNAKALGLGGAATRQ
Mb2547c|M.bovis_AF2122/97 VTMVNDNGRPVAGRLSPDGLRWSTTEQLGYNRRYTLNATALGLGGAATRQ
Rv2518c|M.tuberculosis_H37Rv VTMVNDNGRPVAGRLSPDGLRWSTTEQLGYNRRYTLNATALGLGGAATRQ
MLBr_00426|M.leprae_Br4923 VTMINDNGRMINGQFSPDGLRWSTTEPLGFNRCYTLSAKALGLGGVVNRQ
TH_1098|M.thermoresistible__bu VTMVNEQGRTVEGEFSEDGVSWSTTEPLGYNRQYTITAQSLGLGGVTTRE
MAB_1530|M.abscessus_ATCC_1997 VTMVNSDGKEIAGEIGPDGVTWTTTEPLGYDKQYTINADARGLGGVARAN
Mflv_2800|M.gilvum_PYR-GCK VRMQNEQGRVVAGRLVEGGRAWEPAEPLGYGRSYSLSATGRGADASTVTT
Mvan_3723|M.vanbaalenii_PYR-1 VRMQNEQGRVVAGRMVGGGRAWEPAEPLGYGRSYKLSATGRGADARTVTS
MAV_2751|M.avium_104 VEMVNEGGTAVQGVMTPDNLVWKPTVALGYGRNYTLTITSRGTDGVETKQ
MSMEG_1322|M.smegmatis_MC2_155 VRMLNDAGKEIAGALSPDGKVWKPATALGYGRTYTMNVVARGPGGMPTRA
* * *. * : * : .. * . **:.: *.:. . * ..
MMAR_3872|M.marinum_M M-TFQTSSPAHLTMPYVSPA------DGEVVGVGEPVAIRFDENIANRLA
MUL_3804|M.ulcerans_Agy99 M-TFQTSSPAHLTMPYVSPA------DGEVVGVGEPVAIRFDENIANRLA
Mb2547c|M.bovis_AF2122/97 L-TFQTSSPAHLTMPYVMPG------DGEVVGVGEPVAIRFDENIADRGA
Rv2518c|M.tuberculosis_H37Rv L-TFQTSSPAHLTMPYVMPG------DGEVVGVGEPVAIRFDENIADRGA
MLBr_00426|M.leprae_Br4923 M-TFQTSSPAHLTMPYVNPG------NGEIVGIGEPVAIRFDENIANRLA
TH_1098|M.thermoresistible__bu M-TFETHSPANLTMPYVVPS------PGEVVGVGQPVAVRFDENIPNRAA
MAB_1530|M.abscessus_ATCC_1997 A-TFRTQSPDNMTMPYVMPG------DGEVVGVGQTVAIRFDENIPNRAA
Mflv_2800|M.gilvum_PYR-GCK VSEFSTVAPQSQVGVRLGMTNGASLSEGGVYGVGTVIVATFDADIPDRAA
Mvan_3723|M.vanbaalenii_PYR-1 VSEFSTVAPQSQVGVRLGMTNGASLSEGAVYGVGTVIVATFEADIPDRAA
MAV_2751|M.avium_104 VSTFSTLRPSNQTKVSFTTTSESPLRDGASYGVGTVIVAHFDEQIADRAA
MSMEG_1322|M.smegmatis_MC2_155 SSTFTTVTPTYQANVYLNGTSGAPLKDGETYGVGMVIVARFDQAITDKAS
* * * . . * *:* :. *: *.:: :
MMAR_3872|M.marinum_M AEKAIKITTKPAVEGAFYWLNNREVRWRPEHFWKSGTSVDVAVNTYGVDL
MUL_3804|M.ulcerans_Agy99 AEKAIKITTKPAVEGAFYWLNNREVRWRPEHFWKSGTSVDVAVNTYGVDL
Mb2547c|M.bovis_AF2122/97 AEKAIKITTNPPVEGAFYWLNNREVRWRPEHFWKPGTAVDVAVNTYGVDL
Rv2518c|M.tuberculosis_H37Rv AEKAIKITTNPPVEGAFYWLNNREVRWRPEHFWKPGTAVDVAVNTYGVDL
MLBr_00426|M.leprae_Br4923 AQKAITITANPPVEGAFYWLNNREVRWRPEHFWKSGTAVDVAVNTYGVDL
TH_1098|M.thermoresistible__bu AERAIKVTTNPPVEGAFYWLNNREVRWRPASYWKPGTTVEVEVNTYGVDL
MAB_1530|M.abscessus_ATCC_1997 AEKAIKITTNPPVEGAFYWLNNREVRWRPESFWDSGTSVDVKVNTYGVNL
Mflv_2800|M.gilvum_PYR-GCK AESRLQVITTPQLAGSWMWINDRKAHWRPREYFPSGTEVTVKADLYGTDL
Mvan_3723|M.vanbaalenii_PYR-1 AESRLQVKTSPHVAGSWMWVNDRKAHWRPREYFRSGTEVTVKADLYGTDL
MAV_2751|M.avium_104 AERHLTVTTNPKVTGSWFWVDGQNAHWRPEHYYAPGTTVTAEAKIYGIAL
MSMEG_1322|M.smegmatis_MC2_155 AERRMKVTTSPKAVGSWNWIDDQTAHWRPREYYAPGTKVTVDADIYGARL
*: : : :.* *:: *::.: .:*** :: .** * . .. ** *
MMAR_3872|M.marinum_M GEGMFGEDNVKTHFTIGDEVIATADDNTKMLTIRVNGEVVKTMPTSMGKD
MUL_3804|M.ulcerans_Agy99 GEGMFGEDNVKTHFTIGDEVIATADDNTKMLTILVNGEVVKTMPTSMGKD
Mb2547c|M.bovis_AF2122/97 GEGMFGEDNVQTHFTIGDEVIATADDNTKILTVRVNGEVVKSMPTSMGKD
Rv2518c|M.tuberculosis_H37Rv GEGMFGEDNVQTHFTIGDEVIATADDNTKILTVRVNGEVVKSMPTSMGKD
MLBr_00426|M.leprae_Br4923 GEGMFGEDNVKTHFTIGDEVFATADDATKMLTVRVNGEVVKIMPTSMGKD
TH_1098|M.thermoresistible__bu GDGLFGQRNTKTHFTIGDEVISTVDDNTKTLTVRRNGEVVKTMPVSMGKD
MAB_1530|M.abscessus_ATCC_1997 GDGVFGQDNVASHFTIGDAVISRVDDTNKILNIERNGEIIKTMPTSMGKD
Mflv_2800|M.gilvum_PYR-GCK GSGLFGEQDKQVSFRIGPSRVAIADDTTKQVSVYENGKLIRTMPTSMGRG
Mvan_3723|M.vanbaalenii_PYR-1 GGGLFGEQDKQVSFRIGPSRVAVADDTTKQVSVYENGRLVRTMPTSMGRG
MAV_2751|M.avium_104 GDGLFGQDDSRVSFRIGDAHVSIADDATHQVSVFDNGVLVRTMPTSMGMG
MSMEG_1322|M.smegmatis_MC2_155 GEDLYGAQDEKVSFVIGDSHVSIADDNTKQVSVYENGKLVRTMPTSMGMG
* .::* : * ** .: .** .: :.: ** ::: **.*** .
MMAR_3872|M.marinum_M STPTANG----------IYIVGARFKHIIMDSSTYGVPVNSPNGYRTDVN
MUL_3804|M.ulcerans_Agy99 STPTANG----------IYIVGARFKHIIMDSSTYGVPVNSPNGYRTDVN
Mb2547c|M.bovis_AF2122/97 STPTANG----------IYIVGSRYKHIIMDSSTYGVPVNSPNGYRTDVD
Rv2518c|M.tuberculosis_H37Rv STPTANG----------IYIVGSRYKHIIMDSSTYGVPVNSPNGYRTDVD
MLBr_00426|M.leprae_Br4923 STPTANG----------IYIVGARFKHIIMDSSTYGVPVNSPNGYRADVD
TH_1098|M.thermoresistible__bu STPTNNG----------VYIVGDKRAHMVMDSSTYGVPVNSPNGYRTEVD
MAB_1530|M.abscessus_ATCC_1997 KAPTNNG----------TYIIGERFKDLIMDSSTYGVAVNSPDGYRTKVQ
Mflv_2800|M.gilvum_PYR-GCK GTQTVGGKTIAFWTQPGVYTVMEKQNPVLMDSSTYGLPVDSASGYKISVP
Mvan_3723|M.vanbaalenii_PYR-1 GTQTVGGKTIAFWTQPGVYTVMEKQNPVLMDSSTYGLPVDSASGYKISVP
MAV_2751|M.avium_104 GTENIGGRSISLWTPPGVYTVLDKGNPVVMDSSTFGLPKNSRLGYRETIN
MSMEG_1322|M.smegmatis_MC2_155 GTETVNGVTLSFWTPRGIYTVMDKANPVVMDSSTYGLPVGSRLGYRTTIP
: . .* * : : ::*****:*:. .* **: :
MMAR_3872|M.marinum_M WATQLSYSGVYVHSAPWSVGAQGHTNTSHGCLNVSPSNAEWFYDHIKTGD
MUL_3804|M.ulcerans_Agy99 WATQLSYSGVYVHSAPWSVGAQGHTNTSHGCLNVSPSNAEWFYDHIKTGD
Mb2547c|M.bovis_AF2122/97 WATQISYSGVFVHSAPWSVGAQGHTNTSHGCLNVSPSNAQWFYDHVKRGD
Rv2518c|M.tuberculosis_H37Rv WATQISYSGVFVHSAPWSVGAQGHTNTSHGCLNVSPSNAQWFYDHVKRGD
MLBr_00426|M.leprae_Br4923 WATQLSYSGVFLHSAPWSVGAQGHTNTSHGCLNVSPSNAQWFYDHVKRGD
TH_1098|M.thermoresistible__bu WAVQMSYSGIYVHSAPWSVGSQGYSNVSHGCINVSPSNAKWFYENSKRGD
MAB_1530|M.abscessus_ATCC_1997 YATQMSYSGIYVHAAPWSVGAQGRTNTSHGCLNVSTANAKWFYENTKRGD
Mflv_2800|M.gilvum_PYR-GCK HAVRISPDGIYLHEREATVWAQGNTNVSAGCLNLSAEDAEWYYNFANPGD
Mvan_3723|M.vanbaalenii_PYR-1 HAVRISPDGIYLHEREATVSAQGNTNVSAGCLNLSAENAEWYYEFANPGD
MAV_2751|M.avium_104 YATKISSDGIYLHELDATVWAQGHQDTSHGCLNLNADNAKWFYDFSVPGD
MSMEG_1322|M.smegmatis_MC2_155 YATRISVDGIYLHQLNDTIWAQGNTNVSHGCLNLSGENAQWFYNFSRPGD
*.::* .*:::* :: :** :.* **:*:. :*:*:*: **
MMAR_3872|M.marinum_M IVEVVNTVGGTLPGTEGLGDWNIPWEQWRAGNANA--
MUL_3804|M.ulcerans_Agy99 IVEVVNTVGGTLPGTEGLGDWNIPWEQWRAGNANA--
Mb2547c|M.bovis_AF2122/97 IVEVVNTVGGTLPGIDGLGDWNIPWDQWRAGNAKA--
Rv2518c|M.tuberculosis_H37Rv IVEVVNTVGGTLPGIDGLGDWNIPWDQWRAGNAKA--
MLBr_00426|M.leprae_Br4923 IVEVVNTVGDTLPGAEGLGDWNIPWEQWKAGNANI--
TH_1098|M.thermoresistible__bu IIEVVNTVGTVLPGTDGLGDWNIPWEQWKAGNANV--
MAB_1530|M.abscessus_ATCC_1997 VVIVSNTVGPVLPGTEGLGDWNIPWAQWKAGNARQQ-
Mflv_2800|M.gilvum_PYR-GCK VVEIRNTGGAPLE-QWQNGDWSVPWDEWMGGSALRP-
Mvan_3723|M.vanbaalenii_PYR-1 VVEVRNTGGAPLE-QWQNGDWSVPWDEWVNGSALRP-
MAV_2751|M.avium_104 VVEVRNSGGPPLT-LAQNGDWTLSWDQWRRGSALKPT
MSMEG_1322|M.smegmatis_MC2_155 IVEIRNTGGEPLK-PDNNGDWTIPWEQWRKGSALN--
:: : *: * * ***.:.* :* *.*