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M. gilvum PYR-GCK Mflv_0414 (-)

annotation: TetR family transcriptional regulator
coordinates: 427962 - 428609
length: 215

AGGTKRLPRAVREQQMLDAAVEIFSVNGYHETSMDAIAAEAQISKPMLYLYYGSKEELFGACLHRELTRF
VDEVNSNIDFTAPPKELLRTAVLAFLNYIDANRASWMVLYTQATSSQAFAHTVREGRERIIEIVGRLLRS
GTRFPEPDTDFDMMAVALVGAGEAIASRVSTGDADVHEASELMINLFWRGLKGSPSAASDRDADATDATA
VITS*
Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. gilvum PYR-GCKMflv_0414--100% (215)TetR family transcriptional regulator
M. gilvum PYR-GCKMflv_4672-5e-1630.96% (197) TetR family transcriptional regulator
M. gilvum PYR-GCKMflv_1947-4e-1228.04% (189) TetR family transcriptional regulator

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97Mb0244-2e-8474.49% (196) TetR family transcriptional regulator
M. tuberculosis H37RvRv0238-2e-8474.49% (196) TetR family transcriptional regulator
M. leprae Br4923MLBr_02568-4e-7868.97% (203) putative TetR-family transcriptional regulator
M. abscessus ATCC 19977MAB_4449c-6e-7265.31% (196) TetR family transcriptional regulator
M. marinum MMMAR_0500-2e-8272.08% (197) TetR family transcriptional regulator
M. avium 104MAV_4919-7e-8470.89% (213) transcriptional regulator, TetR family protein
M. smegmatis MC2 155MSMEG_0363-9e-9485.43% (199) TetR-family protein regulatory protein
M. thermoresistible (build 8)TH_1911-1e-8373.30% (206) POSSIBLE TRANSCRIPTIONAL REGULATORY PROTEIN (PROBABLY
M. ulcerans Agy99MUL_1163-6e-8271.57% (197) TetR family transcriptional regulator
M. vanbaalenii PYR-1Mvan_0257-1e-10489.77% (215) TetR family transcriptional regulator

CLUSTAL 2.0.9 multiple sequence alignment


Mflv_0414|M.gilvum_PYR-GCK          --MAGGTKRLPRAVREQQMLDAAVEIFSVNGYHETSMDAIAAEAQISKPM
Mvan_0257|M.vanbaalenii_PYR-1       --MAGGTKRLPRAVREQQMLDAAVEIFSVNGYHETSMDAIAAEAQISKPM
MSMEG_0363|M.smegmatis_MC2_155      MGMAGGTKRLPRAVREQQMLDAAVQMFSVNGYHETSMDAIAAAAEISKPM
TH_1911|M.thermoresistible__bu      ------------------MLDAAVQMFSVNGYHETSMDAIAAQAEISKPM
MMAR_0500|M.marinum_M               --MAGGTKRLPRAIREQQMLDAAVQMFSANGYHETSMDTIAAAAQISKPM
MUL_1163|M.ulcerans_Agy99           --MAGGTKRLPRAIREQQMLDAAVQMFSANGYHETSMDTIAAAAQISKPM
Mb0244|M.bovis_AF2122/97            --MAGGTKRLPRAVREQQMLDAAVQMFSVNGYHETSMDAIAAEAQISKPM
Rv0238|M.tuberculosis_H37Rv         --MAGGTKRLPRAVREQQMLDAAVQMFSVNGYHETSMDAIAAEAQISKPM
MLBr_02568|M.leprae_Br4923          --MAGGAKRIPRAVREQQMLDAAVQMFSVNGYHKTSMDAIAAEAQISKPM
MAV_4919|M.avium_104                --MAGGTKRLPRAVREQQMLDAAVQMFSVNGYHETSMDAIAAQAQISKPM
MAB_4449c|M.abscessus_ATCC_199      --MAGGTKRLPRAVREQQMLDAAVQEFALNGFRDTSMDAIAAAAKISKPM
                                                      ******: *: **::.****:*** *:*****

Mflv_0414|M.gilvum_PYR-GCK          LYLYYGSKEELFGACLHRELTRFVDEVNSNIDFTAPPKELLRTAVLAFLN
Mvan_0257|M.vanbaalenii_PYR-1       LYLYYGSKEELFGACLNRELGRFVDEVNSNIDFSAAPKELLRTAVLAFLK
MSMEG_0363|M.smegmatis_MC2_155      LYLYYGSKEELFGACLDRELRRFVDTVRGQIDFSQSPKELLRTAVLAFLT
TH_1911|M.thermoresistible__bu      LYLYYGSKEELFGACLKRELSRFVETVRADIDFSQSPKDLLRNAVRSFLT
MMAR_0500|M.marinum_M               LYLYYGSKEDLFGACLNREMSRFIDAVRADIDLSQSPKDLLRNAIVSFLR
MUL_1163|M.ulcerans_Agy99           LYLYYGSKEDLFGACLNREMSRFIDAVRADIDLSQSPKDLLRNAIVSFLR
Mb0244|M.bovis_AF2122/97            LYLYYGSKEDLFGACLNREMSRFIDALRSSINFDQSPKDLLRNTIVSFLR
Rv0238|M.tuberculosis_H37Rv         LYLYYGSKEDLFGACLNREMSRFIDALRSSINFDQSPKDLLRNTIVSFLR
MLBr_02568|M.leprae_Br4923          LYLYYGSKEDLFGACLNREMSRFIAMVRADIDFTQSPKDLLRNTIVSFLR
MAV_4919|M.avium_104                LYLYYGSKEDLFGACLNRELGRFIDAVRADIDFQQSPNDMLRNTIASFMR
MAB_4449c|M.abscessus_ATCC_199      LYLYYGSKEDLFVACLRRELGRFVEAVRGDIDLTQSPRDVLSTTVVSFLN
                                    *********:** *** **: **:  :...*::  .*.::* .:: :*: 

Mflv_0414|M.gilvum_PYR-GCK          YIDANRASWMVLYTQATSSQAFAHTVREGRERIIEIVGRLLRSGTRFPEP
Mvan_0257|M.vanbaalenii_PYR-1       YIDANRASWMVLYTQATSSQAFAHTVREGRERIIELVGRLLRSGTKFPEP
MSMEG_0363|M.smegmatis_MC2_155      YIDRNRASWMVLYTQATSSQAFAHTVREGRERIIDLVARLLSTGTRNPQP
TH_1911|M.thermoresistible__bu      YIDTNRASWLVLYTQATSSQAFAHTVREGRERIIDLVARLLRSGTRHPEP
MMAR_0500|M.marinum_M               YIDQNQASWIVMYTQAVSSQAFAQTVREGREQIVELVAGMLRAGTRSPRS
MUL_1163|M.ulcerans_Agy99           YIDQNQASWIVMYTQAVSSQAFAQTVREGREQIVELVAGMLRAGTRSPRS
Mb0244|M.bovis_AF2122/97            YIDANRASWIVMYTQATSSQAFAHTVREGREQIVQLVAELVRAGTRGPLT
Rv0238|M.tuberculosis_H37Rv         YIDANRASWIVMYTQATSSQAFAHTVREGREQIVQLVAELVRAGTRGPLT
MLBr_02568|M.leprae_Br4923          YIDANRASWIVMYIQAMSLPAFAQTVREARDQITELVAGLMRVGTRSSRP
MAV_4919|M.avium_104                YIDANRASWIVMYTQATSSQAFAHMVREGREQIIELVAGLMRAGSRTPRT
MAB_4449c|M.abscessus_ATCC_199      YVDTHRASWIVIYGQATSTQLFAKQVREGRDRIIELVARLIKAASPEIDP
                                    *:* ::***:*:* ** *   **: ***.*::* ::*. ::  .:    .

Mflv_0414|M.gilvum_PYR-GCK          DTDFDMMAVALVGAGEAIASRVSTGDADVHEASELMINLFWRGLKGSPSA
Mvan_0257|M.vanbaalenii_PYR-1       DTDFELMAVALVGAGEAIASRVSTGDADVDEAAELMINLFWLGLKGAPSA
MSMEG_0363|M.smegmatis_MC2_155      DSDFEMMAVALVGAGEAIATRVSTGDADVDEAAELMINLFWRGLKGTPSD
TH_1911|M.thermoresistible__bu      DTDFDMMAVALVGAGEAVATRVSAGDAEVDEAAELLINLFWRGLKGTPAE
MMAR_0500|M.marinum_M               DAEIDMMAAALVGAGEAVANRLSAGDTDVDEAAEMMIDLFWRGLKGAPSD
MUL_1163|M.ulcerans_Agy99           DAEIDMMAAALVGAGEAVANRLSAGDTDVDEAAEMMIDLLWRGLKGAPSD
Mb0244|M.bovis_AF2122/97            DAEIEMMAVALVGAGEAVATRLGIGDTDVDEAAEMMINLFWLGLKGAPVD
Rv0238|M.tuberculosis_H37Rv         DAEIEMMAVALVGAGEAVATRLGIGDTDVDEAAEMMINLFWLGLKGAPVD
MLBr_02568|M.leprae_Br4923          DHEYEIMAGALVGAGEAMATRLTTGDIAVDEAAELMINLFWHGLKGAPAD
MAV_4919|M.avium_104                DREHEMMAVALVGAGEAVANRLSTGDIDVDEAAALMIDLFWYGLKGSPEE
MAB_4449c|M.abscessus_ATCC_199      ETDYDAMAVALVGGGEAVASRVATGDIKVESAKDTLLNLGWRGLRGRPRD
                                    : : : ** ****.***:*.*:  **  *..*   :::* * **:* *  

Mflv_0414|M.gilvum_PYR-GCK          ASDRDA----DATDATAVITS------
Mvan_0257|M.vanbaalenii_PYR-1       AD----------VDATAVISS------
MSMEG_0363|M.smegmatis_MC2_155      AG----------TPPVSAGSSG-----
TH_1911|M.thermoresistible__bu      SHEDTHRENGQDVDRDGVDQSTTV---
MMAR_0500|M.marinum_M               RE----------IGSNFAAG-------
MUL_1163|M.ulcerans_Agy99           RE----------IGSNFAAG-------
Mb0244|M.bovis_AF2122/97            R-----------LETGH----------
Rv0238|M.tuberculosis_H37Rv         R-----------LETGH----------
MLBr_02568|M.leprae_Br4923          RD----------FGPSIVAG-------
MAV_4919|M.avium_104                RE----------AAAAQPEADRSGAGG
MAB_4449c|M.abscessus_ATCC_199      EP----------VAKRA----------