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SVRVNGKPVSGAPQPGQCLRTFLRDHGHFEVKKGCDAGDCGACSVLIDDVAVHSCVYPAFRADGRDVKTV AGLGTSEDLHPMQRRFVEAAGFQCGFCTAGMITTASTFTEEQRANLAEHLKGNLCRCTGYRSITDALDGV SNVEKSGGTTASVGAPAAVRVATGTEPYTMDHTPEGLLHLAVLGSPVAHARIVAIDTSAAEAVPGVRLVL TYLDAPRVAFSTARHEIREDDPDDTYVLDSTVRFVGQRVAAVVADSVAAAETACRAIAVEYEQLPAVFDP DEARSPGAPLLHADKGPDARIADPSRNIVAELHGGIGDVQQAVAAAHTVVRGRYHTQRVQHVHLETHGCT GWVDEDGRLTIRTSTQVPFLVRDELCRIFRLDRDVVRVFATRVGGGFGAKQEMLVEDLVALAVLRLGRPV RYEFSRSDEFTMAPCRHPFRVDVTVAADEDGTLTALAVDVLTDAGAYGNHSPGVMFHGCAESVAVYRCAN KRIDAQSVYTNNLPSGAFRGYGLGQVIFAIESALDELAQRLGIDPFELRRRNVVRPGDRLIDAHEPEDLL FGSYGLDQCLDLTQNALAAGNGAVAPQGWQVGEGMAVAMIATLPPRGHFADATVTLKDDGRYELSVGTAE FGNGTTTVHAQLVATLMNTTVDRVSIRQSDTDAGGYDTGAFGSAGIVVAGRAVHQACVALRATIERAAAE LTGVDAVSCVVGPHGVQCRDRFVPFTELALPLTATGHHDGTPRSVAFNVQGFRVAVNPETGEVRILQSVQ AADAGVVLNPEQCRGQVEGGVAQAIGSALYEEMRVGADGRVLTQTLRNYHIPQLADIPQTKVYFADTYDE LGPLGAKSMSESPYNPVAPALANAIARAVGVRPRELPMTPARIWRALQQGRA*
Operon Prediction Model: Genebank
Paralogs
species | id | gene | e-value | identity (len) | annotation |
M. smegmatis MC2 155 | MSMEG_1291 | - | - | 100% (893) | putative oxidoreductase |
M. smegmatis MC2 155 | MSMEG_2462 | - | 1e-70 | 30.38% (780) | carbon-monoxide dehydrogenase |
M. smegmatis MC2 155 | MSMEG_2949 | - | 4e-66 | 30.09% (771) | carbon-monoxide dehydrogenase |
Closest Orthologs (e-value cutoff: 1e-4)
species | id | gene | e-value | identity (len) | annotation |
M. bovis AF2122 / 97 | Mb0380c | - | 7e-65 | 29.08% (784) | carbon monoxyde dehydrogenase large subunit |
M. gilvum PYR-GCK | Mflv_1573 | - | 2e-63 | 29.73% (767) | carbon-monoxide dehydrogenase (acceptor) |
M. tuberculosis H37Rv | Rv0373c | - | 2e-64 | 29.08% (784) | carbon monoxyde dehydrogenase large subunit |
M. leprae Br4923 | - | - | - | - | - |
M. abscessus ATCC 19977 | MAB_2925c | - | 0.0 | 66.44% (900) | xanthine dehydrogenase family protein |
M. marinum M | MMAR_4945 | - | 0.0 | 72.91% (897) | carbon monoxide dehydrogenase |
M. avium 104 | - | - | - | - | - |
M. thermoresistible (build 8) | TH_1269 | - | 7e-65 | 29.61% (770) | nicotine dehydrogenase |
M. ulcerans Agy99 | MUL_0459 | - | 0.0 | 71.52% (474) | carbon monoxide dehydrogenase |
M. vanbaalenii PYR-1 | Mvan_5281 | - | 0.0 | 74.19% (899) | aldehyde oxidase and xanthine dehydrogenase, molybdopterin |
CLUSTAL 2.0.9 multiple sequence alignment MSMEG_1291|M.smegmatis_MC2_155 MSVRVNGKPVSGAPQPGQCLRTFLRDHGHFEVKKGCDAGDCGACSVLIDD Mvan_5281|M.vanbaalenii_PYR-1 MRITVNGTDRTDDPRPGQCLRTFLRDLGHVEVKKGCDAGDCGACSVLVDG MMAR_4945|M.marinum_M MRFTVNGADLDATPAAGQCLRTFLREHGHFEVKMGCDAGDCGACSVLVDG MUL_0459|M.ulcerans_Agy99 MRFTVNGADLDATPAAGQCLRTFLREHGHFEVKMGCDAGDCGACSVLVDG MAB_2925c|M.abscessus_ATCC_199 --MKVNGKLIDASPRPGQCLRTFLREHGHVEVKKGCDAGDCGACTVLVDG Mb0380c|M.bovis_AF2122/97 -------------------------------------------------- Rv0373c|M.tuberculosis_H37Rv -------------------------------------------------- Mflv_1573|M.gilvum_PYR-GCK -------------------------------------------------- TH_1269|M.thermoresistible__bu -------------------------------------------------- MSMEG_1291|M.smegmatis_MC2_155 VAVHSCVYPAFRADGRDVKTVAGLGTSEDLHPMQRRFVEAAGFQCGFCTA Mvan_5281|M.vanbaalenii_PYR-1 AAVHSCVYPAFRADGRTVTTVAGLGTPKDLHPMQRRFVEAAGFQCGFCTA MMAR_4945|M.marinum_M AAVHSCVFPAFRAAGRTVTTVAGLGTPDDLHPMQRRFAEAAAFQCGFCTA MUL_0459|M.ulcerans_Agy99 AAVHSCVFPAFRAAGRTVTTVAGLGTPDDLHPMQRRFAEAAAFQCGFCTA MAB_2925c|M.abscessus_ATCC_199 ASQHSCIVPAHRVTDAEIHTVRSLAGEHDLHPMQRGFIDHAGFQCGFCTA Mb0380c|M.bovis_AF2122/97 -------------------------------------------------- Rv0373c|M.tuberculosis_H37Rv -------------------------------------------------- Mflv_1573|M.gilvum_PYR-GCK -------------------------------------------------- TH_1269|M.thermoresistible__bu -------------------------------------------------- MSMEG_1291|M.smegmatis_MC2_155 GMITTASTFTEEQRANLAEHLKGNLCRCTGYRSITDALDGVSNVEKSGGT Mvan_5281|M.vanbaalenii_PYR-1 GMVTTASALTADQLEHLPQHLKGNLCRCTGYRAITDAIAGVVNTEKSGGS MMAR_4945|M.marinum_M GLVVTASTFGDDELANLPQHLKGNLCRCTGYRAILDALEGKVNVEKPSGS MUL_0459|M.ulcerans_Agy99 GLVVTASTFGDDELANLPQHLKGNLCRCTGYRAILDALEGKVNVEKPSGS MAB_2925c|M.abscessus_ATCC_199 GMVLTAATLTGDQTEDLGNALKGNLCRCTGYRPIRDAVCGVVPPRG---- Mb0380c|M.bovis_AF2122/97 -------MTTIESRPPSPEDLADNAQQPCGHGRMMRKED----------- Rv0373c|M.tuberculosis_H37Rv -------MTTIESRPPSPEDLADNAQQPCGHGRMMRKED----------- Mflv_1573|M.gilvum_PYR-GCK -------------MTDADVQAVDAVSPRYAGQRVPRVED----------- TH_1269|M.thermoresistible__bu ---------------------------------VPRVED----------- : MSMEG_1291|M.smegmatis_MC2_155 TA--SVGAPAAVRVATGTEPYTMDHTPEGLLHLAVLGSPVAHARIVAIDT Mvan_5281|M.vanbaalenii_PYR-1 DVGRSIGAPAGVRVVTGTEEYTMDDTPVGLLHMAVLASPVPHARIRSIDT MMAR_4945|M.marinum_M DAGRSIGAPAALRVVTGTEPYTTDHAPAGLLHLAVLGSPLAHARITSIDT MUL_0459|M.ulcerans_Agy99 DAGRSIGAPAALRVVTGTEPYTTDHAPAGLLHLAVLGSPLAHARITSIDT MAB_2925c|M.abscessus_ATCC_199 ----SVSAPAAARVVTGTEPYTMDELPAGVGHVAVLGSPHPSARITRIDT Mb0380c|M.bovis_AF2122/97 -----------PRFIRGRGTYVDDVALPGMLHLAILRSPYAHARIVRIDV Rv0373c|M.tuberculosis_H37Rv -----------PRFIRGRGTYVDDVALPGMLHLAILRSPYAHARIVRIDV Mflv_1573|M.gilvum_PYR-GCK -----------SRLLTGQGRFVDDISRPGMLHACFVRSPFARATIRGIDT TH_1269|M.thermoresistible__bu -----------TRLLTGRGTFVDDIIRPGMLHACFVRSPFARATINGIDA *. * :. * *: * ..: ** . * * **. MSMEG_1291|M.smegmatis_MC2_155 SAAEAVPGVRLVLTYLDAPRVAFSTARHEIREDDPDD--TYVLDSTVRFV Mvan_5281|M.vanbaalenii_PYR-1 AAAESIPGVRLVLTHRDSPAVRFSTARHESRDDDPDD--TVILDDTVRFV MMAR_4945|M.marinum_M TAAAAIPGVHLILTHHDSPAVAFSTARHEMRTDDPDD--TYVLDRTVRFI MUL_0459|M.ulcerans_Agy99 TAAATIPGVHLILTHHDSSAVAFSTARHEMRTDDPDD--TYVLDRTVRFI MAB_2925c|M.abscessus_ATCC_199 DRARLLPGVRAVLCYRDDPGVPFSTARHHERTDDPDD--TLVFDRVLRFA Mb0380c|M.bovis_AF2122/97 TAAQAHPKVKAVVTGADLAAKG-LAWMPTLANDVQAV----LATDKTRFQ Rv0373c|M.tuberculosis_H37Rv TAAQAHPKVKAVVTGADLAAKG-LAWMPTLANDVQAV----LATDKTRFQ Mflv_1573|M.gilvum_PYR-GCK SAALALPGVHAVFTASDLNPDVREAWHAVAGKDVPDTPRPPLAEGEVKFV TH_1269|M.thermoresistible__bu SAALAMPGVRAVFTAADINPEVKEAWHAVAGKDVPDTPRPPLAESEAKFV * * *: :. * : * : :* MSMEG_1291|M.smegmatis_MC2_155 GQRVAAVVADSVAAAETACRAIAVEYEQLPAVFDPDEARSP--GAPLLHA Mvan_5281|M.vanbaalenii_PYR-1 GQRVAAVVADSVAVAEAACRAIVVDYEPRPAVFDPDTARRP--GAPLLHA MMAR_4945|M.marinum_M GQRVAAVVADSVAVAEKACRAIQIEYEELPAVFDPEQARAP--GAVLLHA MUL_0459|M.ulcerans_Agy99 GQRVAAVVADSVAVAEKACRAIQIEYEELPAVFDPEQARAARRGALARRQ MAB_2925c|M.abscessus_ATCC_199 GQRVAAVVADTPAIAHRALEHIDVEYEVLPAVFDPEMAQLP--GAHLVHG Mb0380c|M.bovis_AF2122/97 GQEVASVVAEDRYSARDACELVDVDYEPRDPVVDARTALDPSAPVIRTDL Rv0373c|M.tuberculosis_H37Rv GQEVAFVVAEDRYSARDACELVDVDYEPRDPVVDARTALDPSAPVIRTDL Mflv_1573|M.gilvum_PYR-GCK GDPVALVVADSRYLAEDAVDLVEVDYEPLPAVADFRKAVGGASAGVPVVH TH_1269|M.thermoresistible__bu GDPVALVVADSRYIAEDAIELVDVDYEPLPAVADFRQAVN----SDVVVH *: ** ***: *. * : ::** .* * * MSMEG_1291|M.smegmatis_MC2_155 DKGPDARIADPSRN-IVAELHGGIGDVQQAVAAAHT----VVRGRYHTQR Mvan_5281|M.vanbaalenii_PYR-1 DKGPESRIADPSRN-LVAELHGEVGDVAEGVRAAEAGGGAVVRGSWRTQR MMAR_4945|M.marinum_M DKGGQARIADPARN-VVAELHGGTGDVEAGVAAAEASGGAVVRGRWQTAR MUL_0459|M.ulcerans_Agy99 GRPGPHRRPGAQRGRRITWRHRRCRSRRCRRGGLRRSGGARTVADRPSAA MAB_2925c|M.abscessus_ATCC_199 DKGLGARIADPARN-LVAEVHGEVGDVAAALARARESG-AVVTGSWQTAR Mb0380c|M.bovis_AF2122/97 EGKSDNHI-----------FDWETGDAAATEAVFAKADVVVQQEIVYPRV Rv0373c|M.tuberculosis_H37Rv EGKSDNHI-----------FDWETGDAAATEAVFAKADVVVQQEIVYPRV Mflv_1573|M.gilvum_PYR-GCK EAYPDN-------------VAGGMGGMPPDEELFATAPHVVEQHIYQQMY TH_1269|M.thermoresistible__bu EEYPDN-------------VAGGMAGAPPDEETFANAAHVVSEHIYQHAH . MSMEG_1291|M.smegmatis_MC2_155 VQHVHLETHGCTGWVDEDGRLTIRTSTQVPFLVRDELCRIFRLDRDVVRV Mvan_5281|M.vanbaalenii_PYR-1 VQHAHLETHGCTGWRDDAGRLVIRTSSQVPFLVRDELCHIFGLDTDEVRV MMAR_4945|M.marinum_M VQPAHLETHGCTGWRDSRGRLVIRTSSQTPFLVRDELCHVFGLDRDQVHV MUL_0459|M.ulcerans_Agy99 GPPRNPWLHRVAGQPRATG--DPHQLPDTVFGPRRTVPRLRAGPR-PGAR MAB_2925c|M.abscessus_ATCC_199 VQHVHLETHGSVGWQDERGRYVLRTSSQVPFLVRDELCHVFGLAREQVRV Mb0380c|M.bovis_AF2122/97 HPAPMETCGAVADLDPVTGKLTLWTTSQAPHAHRTLYALVAGLPEHKIRV Rv0373c|M.tuberculosis_H37Rv HPAPMETCGAVADLDPVTGKLTLWTTSQAPHAHRTLYALVAGLPEHKIRV Mflv_1573|M.gilvum_PYR-GCK VPVPMETRGMVVEWTSSTDELTIWASTQTPHELRAFAARLLGIPAQGVRV TH_1269|M.thermoresistible__bu VPVPIECRGIVAEWQSASDELTIWASTQTPHELRAFAARLLGIPASRVRV . . .:. . * : MSMEG_1291|M.smegmatis_MC2_155 FATRVGGGFGAKQEMLVEDL-VALAVLRLGRPVRYEFSRSDEFTMAPCRH Mvan_5281|M.vanbaalenii_PYR-1 FTRRVGGGFGGKQEMLAEDL-VALAVLRLGAPVRYEFSRTDEFTVAPCRH MMAR_4945|M.marinum_M FTKRVGGGFGGKQEMLTEDL-VTLAVLRLGRPVRYEFTRVDEFVRATCRH MUL_0459|M.ulcerans_Agy99 FHQAGRRRIRRQTGDAHRGP-GDVGRAETGRPVRYEFTRVDEFVRATCRH MAB_2925c|M.abscessus_ATCC_199 FAPRVGGGFGAKQEMLTEDL-VLLAVRVTGAPVVYEFTRSDQFTIAPCRH Mb0380c|M.bovis_AF2122/97 ISPDIGGGFGNKVPIYPGYVCAIVASLLLDKPVKWMEDRSENLTSTGFAR Rv0373c|M.tuberculosis_H37Rv ISPDIGGGFGNKVPIYPGYVCAIVASLLLDKPVKWMEDRSENLTSTGFAR Mflv_1573|M.gilvum_PYR-GCK IMRDTGGAFGQKVVPMREDMCILLAARRVPAALKWIEDRRENLMSAGQSR TH_1269|M.thermoresistible__bu IVKDTGGGFGQKVVPMREDMCIMIAARKVPAPLKWIEDRRENLMAASQAR : : : :. .: : * ::: : : MSMEG_1291|M.smegmatis_MC2_155 PFRVDVTVAADEDGTLTALAVDVLTDAGAYGNHSPGVMFHG--CAESVAV Mvan_5281|M.vanbaalenii_PYR-1 PFRVEVTVAAGRDGRLTALAVDALVDAGAYGNHSPGVMFHG--CGESVAV MMAR_4945|M.marinum_M PYRIDVTVAADGDGVLTALAVDALMDAGAYGNHTRGVLFHG--CGESVSV MUL_0459|M.ulcerans_Agy99 PYRIDVTVAADGDGVLTALAVDALMDAGAYGNHTRGVLFHG--CGESVSV MAB_2925c|M.abscessus_ATCC_199 PMRVNVTAAADGDGVLTALAVDVLSDAGAYGNHSVGVMFHG--CNESMAQ Mb0380c|M.bovis_AF2122/97 DYIMVGEIAANRDGKILAIRSNVLADHGAFNAQAAPAKYPAGFFGVFTGS Rv0373c|M.tuberculosis_H37Rv DYIMVGEIAANRDGKILAIRSNVLADHGAFNAQAAPAKYPAGFFGVFTGS Mflv_1573|M.gilvum_PYR-GCK HVDGKVRMAFDDDGKILAADIDFIQDVGSY-PTPYPVLTTAAIGMFFPGP TH_1269|M.thermoresistible__bu HVDGDVRMAFDADGTILAADIDFIQDIGSY-PTPYPVLTTAAIGMFFPGP * . ** : * : : * *:: . . . . MSMEG_1291|M.smegmatis_MC2_155 YRCANKRIDAQSVYTNNLPSG-AFRG-YGLGQVIFAIESALDELAQRLGI Mvan_5281|M.vanbaalenii_PYR-1 YRSPNKRVDAEAVYTNNLPSG-AFRG-YGLGQISFAVESAIDELAARLGI MMAR_4945|M.marinum_M YRCANKRIDAEAVYTNNVPSG-AFRG-YGVGQMVFAVESALDDLAQRLGI MUL_0459|M.ulcerans_Agy99 YRCANKRIDAEAVYTNNVPSG-AFRG-YGVGQMVFAVESALDDLAQRLGI MAB_2925c|M.abscessus_ATCC_199 YRCANKRVDAQAVYTNNIPSG-AFRG-YGLGQVLFGIESALDELARNLGI Mb0380c|M.bovis_AF2122/97 YDIEAAYCHMTAVYTNKAPGGVAYACSFRITEAVYFVERLVDCLAFELKM Rv0373c|M.tuberculosis_H37Rv YDIEAAYCHMTAVYTNKAPGGVAYACSFRITEAVYFVERLVDCLAFELKM Mflv_1573|M.gilvum_PYR-GCK YRVPKASFNYKTVFSN-TPGLHAYRGPWQYETLT--REMLLDCAARKIGM TH_1269|M.thermoresistible__bu YRVPKASFNYKTVFSN-TAGLAAYRGPWQYETLS--REILLDIAARKMGM * . :*::* .. *: : * :* * .: : MSMEG_1291|M.smegmatis_MC2_155 DPFELRRRNVVRPG-DRLIDAHEPED-LLFGSYGLDQCLDLTQNALAAGN Mvan_5281|M.vanbaalenii_PYR-1 DPFEFRRRNVVVPG-DTFVDSHVLEDDLTFGSYGLDQCLDLAEAALRAGN MMAR_4945|M.marinum_M DAFEFRRRNVVVPG-DPFVDAHAGENDLTFGSYGLDQCLDLAQDALRRGG MUL_0459|M.ulcerans_Agy99 DAFEFRRRNVVVPG-DPFVDAHAGENDLTFGSYGLDQCLDLAQDALRRGG MAB_2925c|M.abscessus_ATCC_199 DPFEFRRRNVIVPG-DSFVSWEVEEDDLAFGSYGLDQCLDLAQDALARGA Mb0380c|M.bovis_AF2122/97 DPAELRLRNLLRPNQFPYQSKTGWVYDSGDYETTMRKAMNMIGYEALRAE Rv0373c|M.tuberculosis_H37Rv DPAELRLRNLLRPNQFPYQSKTGWVYDSGDYETTMRKAMNMIGYEALRAE Mflv_1573|M.gilvum_PYR-GCK DPVELRRINILRGDEMPFFNPNGMPYDNCAPADTFEQAVKILDHEGFRKE TH_1269|M.thermoresistible__bu DPVDLRRKNLLRRDEMPYFNPNGMPYDHVAPIETFEQAVKMADHEGFRKE *. ::* *:: . . : :.:.: MSMEG_1291|M.smegmatis_MC2_155 G------AVAPQGWQVGEGMAVAMIATLPPR---------GHFADATVTL Mvan_5281|M.vanbaalenii_PYR-1 G------ATAPAGWAVGEGMAVAMIATIPPR---------GHFTEVSVSV MMAR_4945|M.marinum_M RP-----APDGAGWRVGEGMALAMIATLPPG---------GHFGSADISV MUL_0459|M.ulcerans_Agy99 RP-----APDGAGWRVGEGMALAMIATLPPG---------GHFASADISV MAB_2925c|M.abscessus_ATCC_199 ADPARNGSDLPAGWKVGEGMAIAMIATVPPR---------GHVADARAEL Mb0380c|M.bovis_AF2122/97 QK-----QRRARGELMGIGMSFFTEAVGAGPRKDMDILGLGMADGCELRV Rv0373c|M.tuberculosis_H37Rv QK-----QRRARGELMGIGMSFFTEAVGAGPRKDMDILGLGMADGCELRV Mflv_1573|M.gilvum_PYR-GCK QA-----EALAEGRYIGLGFSAYIEPTGAAT-------GNLATEGATVRM TH_1269|M.thermoresistible__bu QE-----EALAQGRYIGLGFSTYIEPTGAAT-------GHLAGEGATIRM * :* *:: .. . : MSMEG_1291|M.smegmatis_MC2_155 KDDGRYELSVGTAEFGNGTTTVHAQLVATLMNTTVDRVSIRQSDTDAGGY Mvan_5281|M.vanbaalenii_PYR-1 DADGVYTLDVGTAEFGNGTTTVHVQLAAAELNTVPERIVVRQSDTATTGY MMAR_4945|M.marinum_M DDAGVYTLCVGTSEFGNGTTTVHAQLTATALGTTSDRIVIRQSDTDVVEH MUL_0459|M.ulcerans_Agy99 DDAGVYTLCVGTSEFGNGTTTVHAQLTATALGTTSDRIVIRQSDTDVVEH MAB_2925c|M.abscessus_ATCC_199 DARGRYRISVGSAEFGNGTTTVHAQLAAGVLGCAPDQVYIHQADTDAVSH Mb0380c|M.bovis_AF2122/97 HPTGKAVLRLSVQTQGQGHETTFAQIVAEELGIAPDDIEVVHGDTDQTPF Rv0373c|M.tuberculosis_H37Rv HPTGKAVLRLSVQTQGQGHETTFAQIVAEELGIAPDDIEVVHGDTDQTPF Mflv_1573|M.gilvum_PYR-GCK ESTGKINVYVNGGSAGNSIETTVVQLTADALGANIDDVATIQGDTAVTPY TH_1269|M.thermoresistible__bu ESTGKINVYVNGGSSGNSIETTVVQLTADALGADIDDVATIQGDTAVTPY . * : :. *:. *. .*:.* :. : : :.** . MSMEG_1291|M.smegmatis_MC2_155 DTGAFGSAGIVVAGRAVHQACVALRATIERAAAELTGVDAVSCVVGPHGV Mvan_5281|M.vanbaalenii_PYR-1 DTGAFGSAGTVVAGLAILAASRELRTALVTAAAELTGAAPSSCVLGRNGV MMAR_4945|M.marinum_M DTGAFGSAGTVIAGRAALAAAQQLRSRIIAAAAEVAGASPADCVLGPHGV MUL_0459|M.ulcerans_Agy99 DTGAFGSAGTVIAGRAALGAAQQLRSRIIAAAAEVAGASPADCVLGPHGV MAB_2925c|M.abscessus_ATCC_199 DTGAFGSAGTTVAGLAVYRAAELLRDQIIRFAATKLAVPQSRCVLEPDGV Mb0380c|M.bovis_AF2122/97 GLGTYGSRSTPVSGGAAALVARKVRDKAKIIASGMLEVSVADLQWEKGKF Rv0373c|M.tuberculosis_H37Rv GLGTYGSRSTPVSGGAAALVARKVRDKAKIIASGMLEVSVADLQWEKGKF Mflv_1573|M.gilvum_PYR-GCK GAGTQGSRSAPMTAGAVNEAGAILRTQIIAIAAQILGVEAAEIELANSRA TH_1269|M.thermoresistible__bu GAGTQGSRSAPMTAGAVHEAGSILRKQIVTIAAHMLDTDESQIELAGSRA . *: ** . ::. * . :* *: . MSMEG_1291|M.smegmatis_MC2_155 QCR---DRFVPFTELAL------PLTATGHHDGTPRSVAFN--------- Mvan_5281|M.vanbaalenii_PYR-1 QCD---ARLVDFGSLPT------PMNRTARHDGTPRSVAFN--------- MMAR_4945|M.marinum_M QCG---QQLVGFGQLPT------PLTGQGSQDGTPRSVSFN--------- MUL_0459|M.ulcerans_Agy99 RCG---QQLVGFGQLPT------PLTGQGSQDGTPRSVSFN--------- MAB_2925c|M.abscessus_ATCC_199 RAG---ADLLGLTEIAASAPE--PLSAVGHHEGTPRSVAFN--------- Mb0380c|M.bovis_AF2122/97 HVKGDPSAAVTIADIAMRAHG-AGDLPEGIEGGLDAEVCYN-PSNLTYPY Rv0373c|M.tuberculosis_H37Rv HVKGDPSAAVTIADIAMRAHG-AGDLPEGIEGGLDAEVCYN-PSNLTYPY Mflv_1573|M.gilvum_PYR-GCK SVRSDPEKSVSFADIAYRSYYDPGQLG-GVSPTLEATARFNSQAMIHWAN TH_1269|M.thermoresistible__bu VVRDDPDKSVSFADLAYRAYYEPQMLPPGTSATLEATARFTSQAPIHWAN : : .:. . . :. MSMEG_1291|M.smegmatis_MC2_155 -VQGFRVAVNPETGEVRILQSVQAADAGVVLNPEQCRGQVEGGVAQAIGS Mvan_5281|M.vanbaalenii_PYR-1 -VHAFRVAVDTETGEVRILQSIQAADAGVVINPQQCRGQVEGGVAQAIGS MMAR_4945|M.marinum_M -VHAFRVAVNTDTGQVEILQSVQAADAGVVLNPEQCRGQVEGSVAQAIGS MUL_0459|M.ulcerans_Agy99 -AHAVRVAVNTDTGQVEILQSVQAADAGVVLNPEQCRGQVEGSVAQAIGS MAB_2925c|M.abscessus_ATCC_199 -VQAFRVAVRPQTGTVRILQSVQTADAGVVVNPQQCRGQVEGGVAQAIGS Mb0380c|M.bovis_AF2122/97 GAYFCVVDIDPGTAVVKVRRFLAVDDCGTRINPMIIEGQVHGGIVDGIGM Rv0373c|M.tuberculosis_H37Rv GAYFCVVDIDPGTAVVKVRRFLAVDDCGTRINPMIIEGQVHGGIVDGIGM Mflv_1573|M.gilvum_PYR-GCK ATHVCTCEVDVETGHVTLTRYIVSEDVGPMINPNIVEGQVAGGTVQGIGG TH_1269|M.thermoresistible__bu ATHACTCEVDTVTGHVTLTNYVVSEDVGPMINPNVVEGQIAGGTVQGIGG . : *. * : . : * * :** .**: *. .:.** MSMEG_1291|M.smegmatis_MC2_155 ALYEEMRVGADGRVLTQTLRNYHIPQLADIPQTKVYFADTYDELGPLGAK Mvan_5281|M.vanbaalenii_PYR-1 ALFEEILIGPDGAVMTKALRDYHIPQVADVPATEVYFADTHDDLGPLGAK MMAR_4945|M.marinum_M ALYEDLQIGPDGRVLTQTLRDYHIPQFVDVPLTEVYFADTFDELGPLGAK MUL_0459|M.ulcerans_Agy99 ALYEDLQIGPDGRVLTQTLRDYHIPQFVDVPLTEVYFADTFDELGPLGAK MAB_2925c|M.abscessus_ATCC_199 ALYEEILVH-DGFVSTTALRNYHIPRLVDVPDTEVYFADTYDTFGPLGAK Mb0380c|M.bovis_AF2122/97 ALMEMIAFDEDGNCLGGSLMDYLIPTALEVPHLETGHTVTPSPHHPIGAK Rv0373c|M.tuberculosis_H37Rv ALMEMIAFDEDGNCLGGSLMDYLIPTALEVPHLETGHTVTPSPHHPIGAK Mflv_1573|M.gilvum_PYR-GCK ALLEKLAYDDDGNPVASTFVDYLLPTATEVPPIEFGHVEIPGPGVG-GYK TH_1269|M.thermoresistible__bu ALLEHQAYDADGNPLSSTFVDYLLPTATEVPLIEYGHIEVPGPGVG-GYK ** * ** :: :* :* ::* : . . * * MSMEG_1291|M.smegmatis_MC2_155 SMSESPYNPVAPALANAIARAVG---VRPRELPMTPARIWRALQQGRA-- Mvan_5281|M.vanbaalenii_PYR-1 SMSESPYNPVAPALANAIARACG---ARVCQLPMTPARVWRAVRASR--- MMAR_4945|M.marinum_M SMAESPYNPVAPALANAIARACG---ARVTRLPMTAARVWRAINSAE--- MUL_0459|M.ulcerans_Agy99 SMAESPYNPMAPALANAIARACG---ARVTRLPMTAARVWRAINSAE--- MAB_2925c|M.abscessus_ATCC_199 SMSESPYNPVAPALANAIRDAVG---VRVYRLPMNAARVWRVINDSGGGE Mb0380c|M.bovis_AF2122/97 GIGESATVGSPPAVVNAVVDALAPFGVRHADMPLTPSRVWEAMQGRATPP Rv0373c|M.tuberculosis_H37Rv GIGESATVGSPPAVVNAVVDALAPFGVRHADMPLTPSRVWEAMQGRATPP Mflv_1573|M.gilvum_PYR-GCK GAGEGGAIGSPPAVINAVNDALAPLGVTLTQLPATPATIVELIDAASRKD TH_1269|M.thermoresistible__bu GAGEGGAIGSTPAVINAINDALAALGVTVTRLPATPATIVELIEQATSKD . .*. .**: **: * . . :* ..: : . : MSMEG_1291|M.smegmatis_MC2_155 ---- Mvan_5281|M.vanbaalenii_PYR-1 ---- MMAR_4945|M.marinum_M ---- MUL_0459|M.ulcerans_Agy99 ---- MAB_2925c|M.abscessus_ATCC_199 SS-- Mb0380c|M.bovis_AF2122/97 I--- Rv0373c|M.tuberculosis_H37Rv I--- Mflv_1573|M.gilvum_PYR-GCK H--- TH_1269|M.thermoresistible__bu QKWN