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MRITVNGTDRTDDPRPGQCLRTFLRDLGHVEVKKGCDAGDCGACSVLVDGAAVHSCVYPAFRADGRTVTT VAGLGTPKDLHPMQRRFVEAAGFQCGFCTAGMVTTASALTADQLEHLPQHLKGNLCRCTGYRAITDAIAG VVNTEKSGGSDVGRSIGAPAGVRVVTGTEEYTMDDTPVGLLHMAVLASPVPHARIRSIDTAAAESIPGVR LVLTHRDSPAVRFSTARHESRDDDPDDTVILDDTVRFVGQRVAAVVADSVAVAEAACRAIVVDYEPRPAV FDPDTARRPGAPLLHADKGPESRIADPSRNLVAELHGEVGDVAEGVRAAEAGGGAVVRGSWRTQRVQHAH LETHGCTGWRDDAGRLVIRTSSQVPFLVRDELCHIFGLDTDEVRVFTRRVGGGFGGKQEMLAEDLVALAV LRLGAPVRYEFSRTDEFTVAPCRHPFRVEVTVAAGRDGRLTALAVDALVDAGAYGNHSPGVMFHGCGESV AVYRSPNKRVDAEAVYTNNLPSGAFRGYGLGQISFAVESAIDELAARLGIDPFEFRRRNVVVPGDTFVDS HVLEDDLTFGSYGLDQCLDLAEAALRAGNGATAPAGWAVGEGMAVAMIATIPPRGHFTEVSVSVDADGVY TLDVGTAEFGNGTTTVHVQLAAAELNTVPERIVVRQSDTATTGYDTGAFGSAGTVVAGLAILAASRELRT ALVTAAAELTGAAPSSCVLGRNGVQCDARLVDFGSLPTPMNRTARHDGTPRSVAFNVHAFRVAVDTETGE VRILQSIQAADAGVVINPQQCRGQVEGGVAQAIGSALFEEILIGPDGAVMTKALRDYHIPQVADVPATEV YFADTHDDLGPLGAKSMSESPYNPVAPALANAIARACGARVCQLPMTPARVWRAVRASR
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. vanbaalenii PYR-1 | Mvan_5281 | - | - | 100% (899) | aldehyde oxidase and xanthine dehydrogenase, molybdopterin binding |
| M. vanbaalenii PYR-1 | Mvan_5183 | - | 2e-57 | 28.46% (780) | carbon-monoxide dehydrogenase (acceptor) |
| M. vanbaalenii PYR-1 | Mvan_2075 | - | 4e-46 | 28.06% (759) | aldehyde oxidase and xanthine dehydrogenase, molybdopterin |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb0380c | - | 9e-68 | 30.09% (771) | carbon monoxyde dehydrogenase large subunit |
| M. gilvum PYR-GCK | Mflv_1573 | - | 3e-59 | 29.05% (778) | carbon-monoxide dehydrogenase (acceptor) |
| M. tuberculosis H37Rv | Rv0373c | - | 2e-67 | 30.09% (771) | carbon monoxyde dehydrogenase large subunit |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | MAB_2925c | - | 0.0 | 65.38% (904) | xanthine dehydrogenase family protein |
| M. marinum M | MMAR_4945 | - | 0.0 | 75.33% (900) | carbon monoxide dehydrogenase |
| M. avium 104 | - | - | - | - | - |
| M. smegmatis MC2 155 | MSMEG_1291 | - | 0.0 | 74.19% (899) | putative oxidoreductase |
| M. thermoresistible (build 8) | TH_0176 | - | 6e-66 | 30.54% (776) | PROBABLE CARBON MONOXYDE DEHYDROGENASE (LARGE CHAIN) |
| M. ulcerans Agy99 | MUL_0459 | - | 0.0 | 72.12% (477) | carbon monoxide dehydrogenase |
CLUSTAL 2.0.9 multiple sequence alignment
Mvan_5281|M.vanbaalenii_PYR-1 MRITVNGTDRTDDPRPGQCLRTFLRDLGHVEVKKGCDAGDCGACSVLVDG
MSMEG_1291|M.smegmatis_MC2_155 MSVRVNGKPVSGAPQPGQCLRTFLRDHGHFEVKKGCDAGDCGACSVLIDD
MMAR_4945|M.marinum_M MRFTVNGADLDATPAAGQCLRTFLREHGHFEVKMGCDAGDCGACSVLVDG
MUL_0459|M.ulcerans_Agy99 MRFTVNGADLDATPAAGQCLRTFLREHGHFEVKMGCDAGDCGACSVLVDG
MAB_2925c|M.abscessus_ATCC_199 --MKVNGKLIDASPRPGQCLRTFLREHGHVEVKKGCDAGDCGACTVLVDG
Mb0380c|M.bovis_AF2122/97 --------------------------------------------------
Rv0373c|M.tuberculosis_H37Rv --------------------------------------------------
TH_0176|M.thermoresistible__bu --------------------------------------------------
Mflv_1573|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_5281|M.vanbaalenii_PYR-1 AAVHSCVYPAFRADGRTVTTVAGLGTPKDLHPMQRRFVEAAGFQCGFCTA
MSMEG_1291|M.smegmatis_MC2_155 VAVHSCVYPAFRADGRDVKTVAGLGTSEDLHPMQRRFVEAAGFQCGFCTA
MMAR_4945|M.marinum_M AAVHSCVFPAFRAAGRTVTTVAGLGTPDDLHPMQRRFAEAAAFQCGFCTA
MUL_0459|M.ulcerans_Agy99 AAVHSCVFPAFRAAGRTVTTVAGLGTPDDLHPMQRRFAEAAAFQCGFCTA
MAB_2925c|M.abscessus_ATCC_199 ASQHSCIVPAHRVTDAEIHTVRSLAGEHDLHPMQRGFIDHAGFQCGFCTA
Mb0380c|M.bovis_AF2122/97 --------------------------------------------------
Rv0373c|M.tuberculosis_H37Rv --------------------------------------------------
TH_0176|M.thermoresistible__bu --------------------------------------------------
Mflv_1573|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_5281|M.vanbaalenii_PYR-1 GMVTTASALTADQLEHLPQHLKGNLCRCTGYRAITDAIAGVVNTEKSGGS
MSMEG_1291|M.smegmatis_MC2_155 GMITTASTFTEEQRANLAEHLKGNLCRCTGYRSITDALDGVSNVEKSGGT
MMAR_4945|M.marinum_M GLVVTASTFGDDELANLPQHLKGNLCRCTGYRAILDALEGKVNVEKPSGS
MUL_0459|M.ulcerans_Agy99 GLVVTASTFGDDELANLPQHLKGNLCRCTGYRAILDALEGKVNVEKPSGS
MAB_2925c|M.abscessus_ATCC_199 GMVLTAATLTGDQTEDLGNALKGNLCRCTGYRPIRDAVCGVVPPRG----
Mb0380c|M.bovis_AF2122/97 -----MTTIESRPPS-PEDLADNAQQPCGHGRMMRKEDP-----------
Rv0373c|M.tuberculosis_H37Rv -----MTTIESRPPS-PEDLADNAQQPCGHGRMMRKEDP-----------
TH_0176|M.thermoresistible__bu -----MTTLESNPAARPDDFENNDQKPCGHGRMLRKEDP-----------
Mflv_1573|M.gilvum_PYR-GCK -----MTDAD-------VQAVDAVSPRYAGQRVPRVEDS-----------
: : . *
Mvan_5281|M.vanbaalenii_PYR-1 DVGRSIGAPAGVRVVTGTEEYTMDDTPVGLLHMAVLASPVPHARIRSIDT
MSMEG_1291|M.smegmatis_MC2_155 TA--SVGAPAAVRVATGTEPYTMDHTPEGLLHLAVLGSPVAHARIVAIDT
MMAR_4945|M.marinum_M DAGRSIGAPAALRVVTGTEPYTTDHAPAGLLHLAVLGSPLAHARITSIDT
MUL_0459|M.ulcerans_Agy99 DAGRSIGAPAALRVVTGTEPYTTDHAPAGLLHLAVLGSPLAHARITSIDT
MAB_2925c|M.abscessus_ATCC_199 ----SVSAPAAARVVTGTEPYTMDELPAGVGHVAVLGSPHPSARITRIDT
Mb0380c|M.bovis_AF2122/97 ------------RFIRGRGTYVDDVALPGMLHLAILRSPYAHARIVRIDV
Rv0373c|M.tuberculosis_H37Rv ------------RFIRGRGTYVDDVALPGMLHLAILRSPYAHARIVRIDV
TH_0176|M.thermoresistible__bu ------------RFIRGRGRYVDDVQLPGMLHLAILRSPYAHARIAGIDT
Mflv_1573|M.gilvum_PYR-GCK ------------RLLTGQGRFVDDISRPGMLHACFVRSPFARATIRGIDT
*. * :. * *: * ..: ** . * * **.
Mvan_5281|M.vanbaalenii_PYR-1 AAAESIPGVRLVLTHRDSPAVRFSTARHESRDDDPDD--TVILDDTVRFV
MSMEG_1291|M.smegmatis_MC2_155 SAAEAVPGVRLVLTYLDAPRVAFSTARHEIREDDPDD--TYVLDSTVRFV
MMAR_4945|M.marinum_M TAAAAIPGVHLILTHHDSPAVAFSTARHEMRTDDPDD--TYVLDRTVRFI
MUL_0459|M.ulcerans_Agy99 TAAATIPGVHLILTHHDSSAVAFSTARHEMRTDDPDD--TYVLDRTVRFI
MAB_2925c|M.abscessus_ATCC_199 DRARLLPGVRAVLCYRDDPGVPFSTARHHERTDDPDD--TLVFDRVLRFA
Mb0380c|M.bovis_AF2122/97 TAAQAHPKVKAVVTGADLAAKG-LAWMPTLANDVQAV----LATDKTRFQ
Rv0373c|M.tuberculosis_H37Rv TAAQAHPKVKAVVTGADLAAKG-LAWMPTLANDVQAV----LATDKTRFQ
TH_0176|M.thermoresistible__bu SAAQAHPKVKAVVTGADLAEKG-LAWMPTLSNDVQAV----LATDKVRFQ
Mflv_1573|M.gilvum_PYR-GCK SAALALPGVHAVFTASDLNPDVREAWHAVAGKDVPDTPRPPLAEGEVKFV
* * *: :. * : * : :*
Mvan_5281|M.vanbaalenii_PYR-1 GQRVAAVVADSVAVAEAACRAIVVDYEPRPAVFDPDTARRP--GAPLLHA
MSMEG_1291|M.smegmatis_MC2_155 GQRVAAVVADSVAAAETACRAIAVEYEQLPAVFDPDEARSP--GAPLLHA
MMAR_4945|M.marinum_M GQRVAAVVADSVAVAEKACRAIQIEYEELPAVFDPEQARAP--GAVLLHA
MUL_0459|M.ulcerans_Agy99 GQRVAAVVADSVAVAEKACRAIQIEYEELPAVFDPEQARAARRGALARRQ
MAB_2925c|M.abscessus_ATCC_199 GQRVAAVVADTPAIAHRALEHIDVEYEVLPAVFDPEMAQLP--GAHLVHG
Mb0380c|M.bovis_AF2122/97 GQEVASVVAEDRYSARDACELVDVDYEPRDPVVDARTALDP--------S
Rv0373c|M.tuberculosis_H37Rv GQEVAFVVAEDRYSARDACELVDVDYEPRDPVVDARTALDP--------S
TH_0176|M.thermoresistible__bu GQEVAFVVAEDHYSARDALELIDVDYDPLDPVVDVRRALEP--------D
Mflv_1573|M.gilvum_PYR-GCK GDPVALVVADSRYLAEDAVDLVEVDYEPLPAVADFRKAVGG--------A
*: ** ***: *. * : ::*: .* * *
Mvan_5281|M.vanbaalenii_PYR-1 DKGPESRIADPSRN-LVAELHGEVGDVAEGVRAAEAGGGAVVRGSWRTQR
MSMEG_1291|M.smegmatis_MC2_155 DKGPDARIADPSRN-IVAELHGGIGDVQQAVAAAHT----VVRGRYHTQR
MMAR_4945|M.marinum_M DKGGQARIADPARN-VVAELHGGTGDVEAGVAAAEASGGAVVRGRWQTAR
MUL_0459|M.ulcerans_Agy99 GRPGPHRRPGAQRGRRITWRHRRCRSRRCRRGGLRRSGGARTVADRPSAA
MAB_2925c|M.abscessus_ATCC_199 DKGLGARIADPARN-LVAEVHGEVGDVAAALARARESG-AVVTGSWQTAR
Mb0380c|M.bovis_AF2122/97 APVIRTDLEGKSDNHIFDWETGDAAATEAVFAKADV----VVQQEIVYPR
Rv0373c|M.tuberculosis_H37Rv APVIRTDLEGKSDNHIFDWETGDAAATEAVFAKADV----VVQQEIVYPR
TH_0176|M.thermoresistible__bu APVIRTDLDGKTDNHCFDWETGDPAATEAAFAKADV----VVEQEIVYPR
Mflv_1573|M.gilvum_PYR-GCK SAGVPVVHEAYPDN--VAGGMGGMPPDEELFATAPH----VVEQHIYQQM
. . .
Mvan_5281|M.vanbaalenii_PYR-1 VQHAHLETHG-CTGWRDDAGRLVIRTSSQVPFLVRDELCHIFGLDTDEVR
MSMEG_1291|M.smegmatis_MC2_155 VQHVHLETHG-CTGWVDEDGRLTIRTSTQVPFLVRDELCRIFRLDRDVVR
MMAR_4945|M.marinum_M VQPAHLETHG-CTGWRDSRGRLVIRTSSQTPFLVRDELCHVFGLDRDQVH
MUL_0459|M.ulcerans_Agy99 GPPRNPWLHR-VAGQPRATG--DPHQLPDTVFGPRRTVPRLRAGPR-PGA
MAB_2925c|M.abscessus_ATCC_199 VQHVHLETHG-SVGWQDERGRYVLRTSSQVPFLVRDELCHVFGLAREQVR
Mb0380c|M.bovis_AF2122/97 VHPAPMETCGAVADLDPVTGKLTLWTTSQAPHAHRTLYALVAGLPEHKIR
Rv0373c|M.tuberculosis_H37Rv VHPAPMETCGAVADLDPVTGKLTLWTTSQAPHAHRTLYALVAGLPEHKIR
TH_0176|M.thermoresistible__bu VHPAPMETCGAVADLDPVTGKLTLWSTSQAPHAHRTLYALVAGLPEHKIR
Mflv_1573|M.gilvum_PYR-GCK YVPVPMETRGMVVEWTSSTDELTIWASTQTPHELRAFAARLLGIPAQGVR
. . .:. . * :
Mvan_5281|M.vanbaalenii_PYR-1 VFTRRVGGGFGGKQEMLAEDL-VALAVLRLGAPVRYEFSRTDEFTVAPCR
MSMEG_1291|M.smegmatis_MC2_155 VFATRVGGGFGAKQEMLVEDL-VALAVLRLGRPVRYEFSRSDEFTMAPCR
MMAR_4945|M.marinum_M VFTKRVGGGFGGKQEMLTEDL-VTLAVLRLGRPVRYEFTRVDEFVRATCR
MUL_0459|M.ulcerans_Agy99 RFHQAGRRRIRRQTGDAHRGP-GDVGRAETGRPVRYEFTRVDEFVRATCR
MAB_2925c|M.abscessus_ATCC_199 VFAPRVGGGFGAKQEMLTEDL-VLLAVRVTGAPVVYEFTRSDQFTIAPCR
Mb0380c|M.bovis_AF2122/97 VISPDIGGGFGNKVPIYPGYVCAIVASLLLDKPVKWMEDRSENLTSTGFA
Rv0373c|M.tuberculosis_H37Rv VISPDIGGGFGNKVPIYPGYVCAIVASLLLDKPVKWMEDRSENLTSTGFA
TH_0176|M.thermoresistible__bu VIAPDIGGGFGNKVPIYPGYVCAIVGSLLLGKPVKWVEDRSENLTSTGFA
Mflv_1573|M.gilvum_PYR-GCK VIMRDTGGAFGQKVVPMREDMCILLAARRVPAALKWIEDRRENLMSAGQS
: : : :. .: : * ::: :
Mvan_5281|M.vanbaalenii_PYR-1 HPFRVEVTVAAGRDGRLTALAVDALVDAGAYGNHSPGVMFHG--CGESVA
MSMEG_1291|M.smegmatis_MC2_155 HPFRVDVTVAADEDGTLTALAVDVLTDAGAYGNHSPGVMFHG--CAESVA
MMAR_4945|M.marinum_M HPYRIDVTVAADGDGVLTALAVDALMDAGAYGNHTRGVLFHG--CGESVS
MUL_0459|M.ulcerans_Agy99 HPYRIDVTVAADGDGVLTALAVDALMDAGAYGNHTRGVLFHG--CGESVS
MAB_2925c|M.abscessus_ATCC_199 HPMRVNVTAAADGDGVLTALAVDVLSDAGAYGNHSVGVMFHG--CNESMA
Mb0380c|M.bovis_AF2122/97 RDYIMVGEIAANRDGKILAIRSNVLADHGAFNAQAAPAKYPAGFFGVFTG
Rv0373c|M.tuberculosis_H37Rv RDYIMVGEIAANRDGKILAIRSNVLADHGAFNAQAAPAKYPAGFFGVFTG
TH_0176|M.thermoresistible__bu RDYIMVGEIAATRDGRILAIRSHVLADHGAFNGTAAPVKYPAGFFGVFTG
Mflv_1573|M.gilvum_PYR-GCK RHVDGKVRMAFDDDGKILAADIDFIQDVGSY-PTPYPVLTTAAIGMFFPG
: * ** : * . : * *:: . . . .
Mvan_5281|M.vanbaalenii_PYR-1 VYRSPNKRVDAEAVYTNNLPSG-AFRG-YGLGQISFAVESAIDELAARLG
MSMEG_1291|M.smegmatis_MC2_155 VYRCANKRIDAQSVYTNNLPSG-AFRG-YGLGQVIFAIESALDELAQRLG
MMAR_4945|M.marinum_M VYRCANKRIDAEAVYTNNVPSG-AFRG-YGVGQMVFAVESALDDLAQRLG
MUL_0459|M.ulcerans_Agy99 VYRCANKRIDAEAVYTNNVPSG-AFRG-YGVGQMVFAVESALDDLAQRLG
MAB_2925c|M.abscessus_ATCC_199 QYRCANKRVDAQAVYTNNIPSG-AFRG-YGLGQVLFGIESALDELARNLG
Mb0380c|M.bovis_AF2122/97 SYDIEAAYCHMTAVYTNKAPGGVAYACSFRITEAVYFVERLVDCLAFELK
Rv0373c|M.tuberculosis_H37Rv SYDIEAAYCHMTAVYTNKAPGGVAYACSFRITEAVYFVERLVDCLAFELK
TH_0176|M.thermoresistible__bu SYDLEAAYCHMTAVYTNKAPGGVAYACSFRITEAVYLVERLVDCLAHELE
Mflv_1573|M.gilvum_PYR-GCK PYRVPKASFNYKTVFSN-TPGLHAYRGPWQYETLTR--EMLLDCAARKIG
* . :*::* *. *: : * :* * .:
Mvan_5281|M.vanbaalenii_PYR-1 IDPFEFRRRNVVVPGDTFVDSHVLEDDLTFGSYGLDQCLDLAEAALRAGN
MSMEG_1291|M.smegmatis_MC2_155 IDPFELRRRNVVRPGDRLIDAHEPED-LLFGSYGLDQCLDLTQNALAAGN
MMAR_4945|M.marinum_M IDAFEFRRRNVVVPGDPFVDAHAGENDLTFGSYGLDQCLDLAQDALRRGG
MUL_0459|M.ulcerans_Agy99 IDAFEFRRRNVVVPGDPFVDAHAGENDLTFGSYGLDQCLDLAQDALRRGG
MAB_2925c|M.abscessus_ATCC_199 IDPFEFRRRNVIVPGDSFVSWEVEEDDLAFGSYGLDQCLDLAQDALARGA
Mb0380c|M.bovis_AF2122/97 MDPAELRLRNLLRPNQ---FPYQSKTGWVYDSGDYETTMRKAMNMIGYEA
Rv0373c|M.tuberculosis_H37Rv MDPAELRLRNLLRPNQ---FPYQSKTGWVYDSGDYETTMRKAMNMIGYEA
TH_0176|M.thermoresistible__bu MDPAELRLRNLLKPDQ---FPYTSKTGWVYDSGDYETTMRKAMAMVGYDE
Mflv_1573|M.gilvum_PYR-GCK MDPVELRRINILRGDE---MPFFNPNGMPYDNCAPADTFEQAVKILDHEG
:*. *:* *:: .: :.. : : :
Mvan_5281|M.vanbaalenii_PYR-1 G------ATAPAGWAVGEGMAVAMIATIPPR-------------GHFTEV
MSMEG_1291|M.smegmatis_MC2_155 G------AVAPQGWQVGEGMAVAMIATLPPR-------------GHFADA
MMAR_4945|M.marinum_M RP-----APDGAGWRVGEGMALAMIATLPPG-------------GHFGSA
MUL_0459|M.ulcerans_Agy99 RP-----APDGAGWRVGEGMALAMIATLPPG-------------GHFASA
MAB_2925c|M.abscessus_ATCC_199 ADPARNGSDLPAGWKVGEGMAIAMIATVPPR-------------GHVADA
Mb0380c|M.bovis_AF2122/97 LR-----AEQKQRRARGELMGIGMSFFTEAVGAGPRKDMDILGLGMADGC
Rv0373c|M.tuberculosis_H37Rv LR-----AEQKQRRARGELMGIGMSFFTEAVGAGPRKDMDILGLGMADGC
TH_0176|M.thermoresistible__bu LR-----AEQAERRRRGELMGIGMSFFTEAVGAGPRKDMDILGLGMADGC
Mflv_1573|M.gilvum_PYR-GCK FR-----KEQAEALAEGRYIGLGFSAYIEPTGAAT-------GNLATEGA
*. :.:.: .
Mvan_5281|M.vanbaalenii_PYR-1 SVSVDADGVYTLDVGTAEFGNGTTTVHVQLAAAELNTVPERIVVRQSDTA
MSMEG_1291|M.smegmatis_MC2_155 TVTLKDDGRYELSVGTAEFGNGTTTVHAQLVATLMNTTVDRVSIRQSDTD
MMAR_4945|M.marinum_M DISVDDAGVYTLCVGTSEFGNGTTTVHAQLTATALGTTSDRIVIRQSDTD
MUL_0459|M.ulcerans_Agy99 DISVDDAGVYTLCVGTSEFGNGTTTVHAQLTATALGTTSDRIVIRQSDTD
MAB_2925c|M.abscessus_ATCC_199 RAELDARGRYRISVGSAEFGNGTTTVHAQLAAGVLGCAPDQVYIHQADTD
Mb0380c|M.bovis_AF2122/97 ELRVHPTGKAVLRLSVQTQGQGHETTFAQIVAEELGIAPDDIEVVHGDTD
Rv0373c|M.tuberculosis_H37Rv ELRVHPTGKAVLRLSVQTQGQGHETTFAQIVAEELGIAPDDIEVVHGDTD
TH_0176|M.thermoresistible__bu ELRVHPTGKAVVRLSVQTQGQGHETTFAQIVAEELGIPPDDIEVVHGDTD
Mflv_1573|M.gilvum_PYR-GCK TVRMESTGKINVYVNGGSAGNSIETTVVQLTADALGANIDDVATIQGDTA
:. * : :. *:. *. .*:.* :. : : :.**
Mvan_5281|M.vanbaalenii_PYR-1 TTGYDTGAFGSAGTVVAGLAILAASRELRTALVTAAAELTGAAPSSCVLG
MSMEG_1291|M.smegmatis_MC2_155 AGGYDTGAFGSAGIVVAGRAVHQACVALRATIERAAAELTGVDAVSCVVG
MMAR_4945|M.marinum_M VVEHDTGAFGSAGTVIAGRAALAAAQQLRSRIIAAAAEVAGASPADCVLG
MUL_0459|M.ulcerans_Agy99 VVEHDTGAFGSAGTVIAGRAALGAAQQLRSRIIAAAAEVAGASPADCVLG
MAB_2925c|M.abscessus_ATCC_199 AVSHDTGAFGSAGTTVAGLAVYRAAELLRDQIIRFAATKLAVPQSRCVLE
Mb0380c|M.bovis_AF2122/97 QTPFGLGTYGSRSTPVSGGAAALVARKVRDKAKIIASGMLEVSVADLQWE
Rv0373c|M.tuberculosis_H37Rv QTPFGLGTYGSRSTPVSGGAAALVARKVRDKAKIIASGMLEVSVADLQWE
TH_0176|M.thermoresistible__bu QTPFGLGTYGSRSTPVSGAAAALVARKVRDKAKIIASGMLEASIADLEWE
Mflv_1573|M.gilvum_PYR-GCK VTPYGAGTQGSRSAPMTAGAVNEAGAILRTQIIAIAAQILGVEAAEIELA
.. *: ** . ::. * . :* *: .
Mvan_5281|M.vanbaalenii_PYR-1 RNGVQCD---ARLVDFGSLPT-----PMNRTARHDGTPRSVAFN------
MSMEG_1291|M.smegmatis_MC2_155 PHGVQCR---DRFVPFTELAL-----PLTATGHHDGTPRSVAFN------
MMAR_4945|M.marinum_M PHGVQCG---QQLVGFGQLPT-----PLTGQGSQDGTPRSVSFN------
MUL_0459|M.ulcerans_Agy99 PHGVRCG---QQLVGFGQLPT-----PLTGQGSQDGTPRSVSFN------
MAB_2925c|M.abscessus_ATCC_199 PDGVRAG---ADLLGLTEIAASAP-EPLSAVGHHEGTPRSVAFN------
Mb0380c|M.bovis_AF2122/97 KGKFHVKGDPSAAVTIADIAMRAHGAGDLPEGIEGGLDAEVCYN-PSNLT
Rv0373c|M.tuberculosis_H37Rv KGKFHVKGDPSAAVTIADIAMRAHGAGDLPEGIEGGLDAEVCYN-PSNLT
TH_0176|M.thermoresistible__bu KGSFRVKGDPSASVTIQDIAMRAHGAGDLPDGIEGGLDAQICYN-PSNLT
Mflv_1573|M.gilvum_PYR-GCK NSRASVRSDPEKSVSFADIAYRSYYDPGQLGGVSPTLEATARFNSQAMIH
: : .:. . :*
Mvan_5281|M.vanbaalenii_PYR-1 ----VHAFRVAVDTETGEVRILQSIQAADAGVVINPQQCRGQVEGGVAQA
MSMEG_1291|M.smegmatis_MC2_155 ----VQGFRVAVNPETGEVRILQSVQAADAGVVLNPEQCRGQVEGGVAQA
MMAR_4945|M.marinum_M ----VHAFRVAVNTDTGQVEILQSVQAADAGVVLNPEQCRGQVEGSVAQA
MUL_0459|M.ulcerans_Agy99 ----AHAVRVAVNTDTGQVEILQSVQAADAGVVLNPEQCRGQVEGSVAQA
MAB_2925c|M.abscessus_ATCC_199 ----VQAFRVAVRPQTGTVRILQSVQTADAGVVVNPQQCRGQVEGGVAQA
Mb0380c|M.bovis_AF2122/97 YPYGAYFCVVDIDPGTAVVKVRRFLAVDDCGTRINPMIIEGQVHGGIVDG
Rv0373c|M.tuberculosis_H37Rv YPYGAYFCVVDIDPGTAVVKVRRFLAVDDCGTRINPMIIEGQVHGGIVDG
TH_0176|M.thermoresistible__bu YPYGAYFCVVDVDPGTAVVKVRRFLAVDDCGTRINPMIIEGQVHGGIVDG
Mflv_1573|M.gilvum_PYR-GCK WANATHVCTCEVDVETGHVTLTRYIVSEDVGPMINPNIVEGQVAGGTVQG
. : *. * : : : * * :** .*** *. .:.
Mvan_5281|M.vanbaalenii_PYR-1 IGSALFEEILIGPDGAVMTKALRDYHIPQVADVPATEVYFADTHDDLGPL
MSMEG_1291|M.smegmatis_MC2_155 IGSALYEEMRVGADGRVLTQTLRNYHIPQLADIPQTKVYFADTYDELGPL
MMAR_4945|M.marinum_M IGSALYEDLQIGPDGRVLTQTLRDYHIPQFVDVPLTEVYFADTFDELGPL
MUL_0459|M.ulcerans_Agy99 IGSALYEDLQIGPDGRVLTQTLRDYHIPQFVDVPLTEVYFADTFDELGPL
MAB_2925c|M.abscessus_ATCC_199 IGSALYEEILVH-DGFVSTTALRNYHIPRLVDVPDTEVYFADTYDTFGPL
Mb0380c|M.bovis_AF2122/97 IGMALMEMIAFDEDGNCLGGSLMDYLIPTALEVPHLETGHTVTPSPHHPI
Rv0373c|M.tuberculosis_H37Rv IGMALMEMIAFDEDGNCLGGSLMDYLIPTALEVPHLETGHTVTPSPHHPI
TH_0176|M.thermoresistible__bu IGMALMQMIGFDEDGNCLGGSLMDYLIPTAMEVPTLETGFTVTPSPHHPI
Mflv_1573|M.gilvum_PYR-GCK IGGALLEKLAYDDDGNPVASTFVDYLLPTATEVPPIEFGHVEIPGPGVG-
** ** : : ** :: :* :* ::* : .. .
Mvan_5281|M.vanbaalenii_PYR-1 GAKSMSESPYNPVAPALANAIARACG---ARVCQLPMTPARVWRAVRASR
MSMEG_1291|M.smegmatis_MC2_155 GAKSMSESPYNPVAPALANAIARAVG---VRPRELPMTPARIWRALQQGR
MMAR_4945|M.marinum_M GAKSMAESPYNPVAPALANAIARACG---ARVTRLPMTAARVWRAINSAE
MUL_0459|M.ulcerans_Agy99 GAKSMAESPYNPMAPALANAIARACG---ARVTRLPMTAARVWRAINSAE
MAB_2925c|M.abscessus_ATCC_199 GAKSMSESPYNPVAPALANAIRDAVG---VRVYRLPMNAARVWRVINDSG
Mb0380c|M.bovis_AF2122/97 GAKGIGESATVGSPPAVVNAVVDALAPFGVRHADMPLTPSRVWEAMQGRA
Rv0373c|M.tuberculosis_H37Rv GAKGIGESATVGSPPAVVNAVVDALAPFGVRHADMPLTPSRVWEAMQGRA
TH_0176|M.thermoresistible__bu GAKGIGESATVGSPPAVVNAVVDALAPFGVRHVDMPLTPSRVWEAMQGRA
Mflv_1573|M.gilvum_PYR-GCK GYKGAGEGGAIGSPPAVINAVNDALAPLGVTLTQLPATPATIVELIDAAS
* *. .*. .**: **: * . . :* ..: : . :
Mvan_5281|M.vanbaalenii_PYR-1 -----
MSMEG_1291|M.smegmatis_MC2_155 A----
MMAR_4945|M.marinum_M -----
MUL_0459|M.ulcerans_Agy99 -----
MAB_2925c|M.abscessus_ATCC_199 GGESS
Mb0380c|M.bovis_AF2122/97 TPPI-
Rv0373c|M.tuberculosis_H37Rv TPPI-
TH_0176|M.thermoresistible__bu QPSI-
Mflv_1573|M.gilvum_PYR-GCK RKDH-