For questions or suggestions e-mail us at: ioerger@cs.tamu.edu
MDTRTAPGRWPKRHALEFATGQARFVDDIRPQGLLHMAVVRSTRAHARIVSVDVSAAAARPGVVLVLDAH EAARHLETLPYQFGAPELLGARNVALQALPVDKVRYVGEPVAVLAAENPRAARAAAAAVAVEYDDLPEAP RPYEYLGTSVLSAEQREHVVTENHFSSGDPDGALARAEHLLDAEFTVGRSTTAPLETRGYVASWDASAQR LTVHASHQQPFQLRDELAEVLRLAPEAIRVVVPNVGGSFGLKMTGQVEEPLVCLLSMLCERPVKWIESRA ECFLGGGREQIHRVRAGFGGDGRVEVFTDHMVVPVGARSVSPGWRQAYVSAASLPGPYDIPHVDVTSRVV TTNLPPWHSCRGFGKEAPVFVMERVMDLIARRLRLDPAEVRRRNLLPTSAFPHRMPSGYQIDSGDYRAVL DRVIDISGYTGTHQQPSSATVRRGVGISFEITPEGGGHASGRLAPNVTPTVAAAESATVRLDRDGHVTVL SGVTNPGGGNDTALARLAAETLGTTTENVTVVQGDTSLCPPGTGNASSRGVAVGGAAVVLAARDMADKLR RTAAATLGCAPHEVTLADDAAHAASGASIPLRNLCARAAECGELSYTRSYRPTPPDDPAYRYSYPYFSSG AYVAEVDVDTATGVVKVHAITAVHDCGRVVEPVLVEGQLQGAIAMGIGLALYEDNRFEADGAPATRTFKE YMVPRANDLPDFVIRHHETPAPHTLLGAKGAGEAGVGGALAAVANAIDDALQGAQHGAGEPIATVTSVPL DPPTVLSLIPEPRGLG
Operon Prediction Model: Genebank
Paralogs
species | id | gene | e-value | identity (len) | annotation |
M. smegmatis MC2 155 | MSMEG_2949 | - | - | 100% (786) | carbon-monoxide dehydrogenase |
M. smegmatis MC2 155 | MSMEG_2462 | - | 2e-99 | 33.07% (768) | carbon-monoxide dehydrogenase |
M. smegmatis MC2 155 | MSMEG_0746 | - | 7e-91 | 31.58% (779) | carbon-monoxide dehydrogenase, large subunit |
Closest Orthologs (e-value cutoff: 1e-4)
species | id | gene | e-value | identity (len) | annotation |
M. bovis AF2122 / 97 | Mb0380c | - | 2e-90 | 30.87% (784) | carbon monoxyde dehydrogenase large subunit |
M. gilvum PYR-GCK | Mflv_1573 | - | 1e-86 | 29.29% (792) | carbon-monoxide dehydrogenase (acceptor) |
M. tuberculosis H37Rv | Rv0373c | - | 1e-90 | 30.87% (784) | carbon monoxyde dehydrogenase large subunit |
M. leprae Br4923 | - | - | - | - | - |
M. abscessus ATCC 19977 | MAB_2925c | - | 8e-58 | 29.54% (765) | xanthine dehydrogenase family protein |
M. marinum M | MMAR_0657 | coxL | 5e-94 | 31.79% (780) | carbon monoxyde dehydrogenase (large chain), CoxL |
M. avium 104 | - | - | - | - | - |
M. thermoresistible (build 8) | TH_0176 | - | 6e-92 | 31.80% (783) | PROBABLE CARBON MONOXYDE DEHYDROGENASE (LARGE CHAIN) |
M. ulcerans Agy99 | MUL_0115 | coxL | 1e-89 | 31.03% (780) | carbon monoxyde dehydrogenase (large chain), CoxL |
M. vanbaalenii PYR-1 | Mvan_5183 | - | 2e-85 | 29.73% (804) | carbon-monoxide dehydrogenase (acceptor) |
CLUSTAL 2.0.9 multiple sequence alignment Mb0380c|M.bovis_AF2122/97 -------------------------------------------------- Rv0373c|M.tuberculosis_H37Rv -------------------------------------------------- MMAR_0657|M.marinum_M -------------------------------------------------- MUL_0115|M.ulcerans_Agy99 -------------------------------------------------- TH_0176|M.thermoresistible__bu -------------------------------------------------- Mflv_1573|M.gilvum_PYR-GCK -------------------------------------------------- Mvan_5183|M.vanbaalenii_PYR-1 -------------------------------------------------- MSMEG_2949|M.smegmatis_MC2_155 -------------------------------------------------- MAB_2925c|M.abscessus_ATCC_199 MKVNGKLIDASPRPGQCLRTFLREHGHVEVKKGCDAGDCGACTVLVDGAS Mb0380c|M.bovis_AF2122/97 -------------------------------------------------- Rv0373c|M.tuberculosis_H37Rv -------------------------------------------------- MMAR_0657|M.marinum_M -------------------------------------------------- MUL_0115|M.ulcerans_Agy99 -------------------------------------------------- TH_0176|M.thermoresistible__bu -------------------------------------------------- Mflv_1573|M.gilvum_PYR-GCK -------------------------------------------------- Mvan_5183|M.vanbaalenii_PYR-1 -------------------------------------------------- MSMEG_2949|M.smegmatis_MC2_155 -------------------------------------------------- MAB_2925c|M.abscessus_ATCC_199 QHSCIVPAHRVTDAEIHTVRSLAGEHDLHPMQRGFIDHAGFQCGFCTAGM Mb0380c|M.bovis_AF2122/97 ------------------MTTIESRPPS-PEDLADNAQQPCGHGRMMRKE Rv0373c|M.tuberculosis_H37Rv ------------------MTTIESRPPS-PEDLADNAQQPCGHGRMMRKE MMAR_0657|M.marinum_M ------------------MTTIESRP----EDLADNDQKPCGHGRMLRKE MUL_0115|M.ulcerans_Agy99 ------------------MTTIESRP----EDLADNDQKPCGHGRMLRKE TH_0176|M.thermoresistible__bu ------------------MTTLESNPAARPDDFENNDQKPCGHGRMLRKE Mflv_1573|M.gilvum_PYR-GCK ------------------MTDADVQ-------AVDAVSPRYAGQRVPRVE Mvan_5183|M.vanbaalenii_PYR-1 ------------------MTDT----------ATNAVTARYAGQRVPRVE MSMEG_2949|M.smegmatis_MC2_155 ------------------------------------MDTRTAPGRWPKRH MAB_2925c|M.abscessus_ATCC_199 VLTAATLTGDQTEDLGNALKGNLCRCTGYRPIRDAVCGVVPPRGSVSAPA Mb0380c|M.bovis_AF2122/97 DPRFIRGRGTYVDDVALPGMLHLAILRSPYAHARIVRIDVTAAQAHPKVK Rv0373c|M.tuberculosis_H37Rv DPRFIRGRGTYVDDVALPGMLHLAILRSPYAHARIVRIDVTAAQAHPKVK MMAR_0657|M.marinum_M DPRFIRGRGNYVDDVALPGMLHLAILRSPYAHARIVSIDVTAALAHPKVK MUL_0115|M.ulcerans_Agy99 DPRFIRGRGNYVDDVALPGMLHLAIFRSPYAHARIVSIDVTAALAHPKVK TH_0176|M.thermoresistible__bu DPRFIRGRGRYVDDVQLPGMLHLAILRSPYAHARIAGIDTSAAQAHPKVK Mflv_1573|M.gilvum_PYR-GCK DSRLLTGQGRFVDDISRPGMLHACFVRSPFARATIRGIDTSAALALPGVH Mvan_5183|M.vanbaalenii_PYR-1 DSRLLTGHGRFVDDISRPGMLHACFVRSPFAHATINGVDASAALALPGVH MSMEG_2949|M.smegmatis_MC2_155 ALEFATGQARFVDDIRPQGLLHMAVVRSTRAHARIVSVDVSAAAARPGVV MAB_2925c|M.abscessus_ATCC_199 AARVVTGTEPYTMDELPAGVGHVAVLGSPHPSARITRIDTDRARLLPGVR .. * :. * *: * ... *. . * * :*. * * * Mb0380c|M.bovis_AF2122/97 AVVTGADLAAKG-LAWMPTLANDVQAV-------LATDKTRFQGQEVASV Rv0373c|M.tuberculosis_H37Rv AVVTGADLAAKG-LAWMPTLANDVQAV-------LATDKTRFQGQEVAFV MMAR_0657|M.marinum_M AVVTGADLAEKG-LAWMPTLSNDVQAV-------LATDKVRFQGQEVAFV MUL_0115|M.ulcerans_Agy99 AVVTGADLAEKG-LAWMPTLSNDVQAV-------LATDKVHFQGQEVVFV TH_0176|M.thermoresistible__bu AVVTGADLAEKG-LAWMPTLSNDVQAV-------LATDKVRFQGQEVAFV Mflv_1573|M.gilvum_PYR-GCK AVFTASDLNPDVREAWHAVAGKDVPDTP---RPPLAEGEVKFVGDPVALV Mvan_5183|M.vanbaalenii_PYR-1 AVFTAADLNPDVKEAWHAVAGKDVPDTP---RPPLAEGEVKFVGDPVALV MSMEG_2949|M.smegmatis_MC2_155 LVLDAHEAARHLETLPYQFGAPELLGARNVALQALPVDKVRYVGEPVAVL MAB_2925c|M.abscessus_ATCC_199 AVLCYRDDPGVPFSTARHHERTDDPDDT-----LVFDRVLRFAGQRVAAV *. : : : :: *: *. : Mb0380c|M.bovis_AF2122/97 VAEDRYSARDACELVDVDYEPRDPVVDARTALDP--------SAPVIRTD Rv0373c|M.tuberculosis_H37Rv VAEDRYSARDACELVDVDYEPRDPVVDARTALDP--------SAPVIRTD MMAR_0657|M.marinum_M VAEDRYSARDALELIDVEYDPLDPVVDVRKALDP--------SAPVIRTD MUL_0115|M.ulcerans_Agy99 VAEDRYSARDALELIDVEYDPLDPVVDVRKALHP--------SAPVIRTD TH_0176|M.thermoresistible__bu VAEDHYSARDALELIDVDYDPLDPVVDVRRALEP--------DAPVIRTD Mflv_1573|M.gilvum_PYR-GCK VADSRYLAEDAVDLVEVDYEPLPAVADFRKAVGG--------ASAGVPVV Mvan_5183|M.vanbaalenii_PYR-1 VADSRYLAEDAVDLVEVDYDPLPAVADFRKAVGG--------AEAGVPVV MSMEG_2949|M.smegmatis_MC2_155 AAENPRAARAAAAAVAVEYDDLPEAPRPYEYLGT--------SVLSAEQR MAB_2925c|M.abscessus_ATCC_199 VADTPAIAHRALEHIDVEYEVLPAVFDPEMAQLPGAHLVHGDKGLGARIA .*: *. * : *:*: . Mb0380c|M.bovis_AF2122/97 LEGKSDNHIFDWETGDAAATEAVFAKADVVVQQEIVYPRVHPAPMETCGA Rv0373c|M.tuberculosis_H37Rv LEGKSDNHIFDWETGDAAATEAVFAKADVVVQQEIVYPRVHPAPMETCGA MMAR_0657|M.marinum_M LDGKQDNHIFDWETGDAAATDAVFAKADVVIKQEMVYPRVHPAPMETCGA MUL_0115|M.ulcerans_Agy99 LDGKQDNHIFDWETGDAAATDAVFAKADVVIKQEMVYPRVHPAPMETCGA TH_0176|M.thermoresistible__bu LDGKTDNHCFDWETGDPAATEAAFAKADVVVEQEIVYPRVHPAPMETCGA Mflv_1573|M.gilvum_PYR-GCK HEAYPDN--VAGGMGGMPPDEELFATAPHVVEQHIYQQMYVPVPMETRGM Mvan_5183|M.vanbaalenii_PYR-1 HAAYPDN--VAGGMGGMPPDEEIFATAAHVVEEHIYQQMYVPVPMETRGM MSMEG_2949|M.smegmatis_MC2_155 EHVVTENHFSSGDP------DGALARAEHLLDAEFTVGRSTTAPLETRGY MAB_2925c|M.abscessus_ATCC_199 DPARNLVAEVHGEVGDVAAALARARESGAVVTGSWQTARVQHVHLETHGS : :: . :** * Mb0380c|M.bovis_AF2122/97 VADLDPVTGKLTLWTTSQAPHAHRTLYALVAGLPEHKIRVISPDIGGGFG Rv0373c|M.tuberculosis_H37Rv VADLDPVTGKLTLWTTSQAPHAHRTLYALVAGLPEHKIRVISPDIGGGFG MMAR_0657|M.marinum_M VADLDPVTGKLTLWTTSQAPHAHRTLYALVAGLPEHKIRVISPDIGGGFG MUL_0115|M.ulcerans_Agy99 VADLDPVTGKLTLWTTSQAPHAHRTLYALVAGLPEHKIRVISPDIGGGFG TH_0176|M.thermoresistible__bu VADLDPVTGKLTLWSTSQAPHAHRTLYALVAGLPEHKIRVIAPDIGGGFG Mflv_1573|M.gilvum_PYR-GCK VVEWTSSTDELTIWASTQTPHELRAFAARLLGIPAQGVRVIMRDTGGAFG Mvan_5183|M.vanbaalenii_PYR-1 VVEWTSTTNELTVWASTQTPHELRAFAARLLGIPAQGVRVIMRDTGGAFG MSMEG_2949|M.smegmatis_MC2_155 VASWDASAQRLTVHASHQQPFQLRDELAEVLRLAPEAIRVVVPNVGGSFG MAB_2925c|M.abscessus_ATCC_199 VG-WQDERGRYVLRTSSQVPFLVRDELCHVFGLAREQVRVFAPRVGGGFG * . .: :: * *. * . : :. . :**. **.** Mb0380c|M.bovis_AF2122/97 NKVPIYPGYVCAIVASLLLD---------KPVKWMEDRSENLTSTGFARD Rv0373c|M.tuberculosis_H37Rv NKVPIYPGYVCAIVASLLLD---------KPVKWMEDRSENLTSTGFARD MMAR_0657|M.marinum_M NKVPIYPGYVCAIVGSLVLG---------KPVKWMEDRSENLTSTSFARD MUL_0115|M.ulcerans_Agy99 NKVPIYPGYVCAIVGSSVLG---------KPVKWMEDRSENLTSTSFARD TH_0176|M.thermoresistible__bu NKVPIYPGYVCAIVGSLLLG---------KPVKWVEDRSENLTSTGFARD Mflv_1573|M.gilvum_PYR-GCK QKVVPMREDMCILLAARRVP---------AALKWIEDRRENLMSAGQSRH Mvan_5183|M.vanbaalenii_PYR-1 QKVVPMREDMCILLAARKMPTATSNAQSGVAVKWIEDRRENLMSAGQSRH MSMEG_2949|M.smegmatis_MC2_155 LKMTGQVEEPLVCLLSMLCER---------PVKWIESRAECFLGGG--RE MAB_2925c|M.abscessus_ATCC_199 AKQEMLTEDLVLLAVRVTGA----------PVVYEFTRSDQFTIAPCRHP * .: : * : : : Mb0380c|M.bovis_AF2122/97 YIMVGEIAANRDGKILAIRSNVLADHGAFNAQAAPAKYPAGFFGVFTGSY Rv0373c|M.tuberculosis_H37Rv YIMVGEIAANRDGKILAIRSNVLADHGAFNAQAAPAKYPAGFFGVFTGSY MMAR_0657|M.marinum_M YIMVGEIAATNEGKILALRSHVLADHGAFNGQAAPTKYPAGFYGVFTGSY MUL_0115|M.ulcerans_Agy99 YIMVGEIAATNEGKILALRSHVLADHGAFNGQAAPTKYPAGFYGVFTGSY TH_0176|M.thermoresistible__bu YIMVGEIAATRDGRILAIRSHVLADHGAFNGTAAPVKYPAGFFGVFTGSY Mflv_1573|M.gilvum_PYR-GCK VDGKVRMAFDDDGKILAADIDFIQDVGSYP-TPYPVLTTAAIGMFFPGPY Mvan_5183|M.vanbaalenii_PYR-1 VDGKVRMAFDSDGKILAADIDFVQDVGSYP-TPYPVLTTAAIGMFFPGPY MSMEG_2949|M.smegmatis_MC2_155 QIHRVRAGFGGDGRVEVFTDHMVVPVGARS-VSPGWRQAYVSAASLPGPY MAB_2925c|M.abscessus_ATCC_199 MRVNVTAAADGDGVLTALAVDVLSDAGAYGNHSVGVMFHG--CNESMAQY . :* : . ..: *: . . * Mb0380c|M.bovis_AF2122/97 DIEAAYCHMTAVYTNKAPGGVAYACSFRITEAVYFVERLVDCLAFELKMD Rv0373c|M.tuberculosis_H37Rv DIEAAYCHMTAVYTNKAPGGVAYACSFRITEAVYFVERLVDCLAFELKMD MMAR_0657|M.marinum_M DLEAAYCHMTAVYTNKAPGGVAYACSFRITEAVYFVERLVDCLAFELKMD MUL_0115|M.ulcerans_Agy99 DLEAAYCHMTAVYTNKAPGGVAYACSFRITEAVYFVERLVDCLAFELKMG TH_0176|M.thermoresistible__bu DLEAAYCHMTAVYTNKAPGGVAYACSFRITEAVYLVERLVDCLAHELEMD Mflv_1573|M.gilvum_PYR-GCK RVPKASFNYKTVFSNTPG---LHAYRGPWQYETLTREMLLDCAARKIGMD Mvan_5183|M.vanbaalenii_PYR-1 RVPKASFNYKTVFSNTPG---LHAYRGPWQYETLTREMLLDSAARKIGMD MSMEG_2949|M.smegmatis_MC2_155 DIPHVDVTSRVVTTNLPP--WHSCRGFGKEAPVFVMERVMDLIARRLRLD MAB_2925c|M.abscessus_ATCC_199 RCANKRVDAQAVYTNNIP--SGAFRGYGLGQVLFGIESALDELARNLGID .* :* * :* * .: :. Mb0380c|M.bovis_AF2122/97 PAELRLRNLLRPNQFPYQSKTGWVYDSGDYETTMRKAMNMIGYEALRAEQ Rv0373c|M.tuberculosis_H37Rv PAELRLRNLLRPNQFPYQSKTGWVYDSGDYETTMRKAMNMIGYEALRAEQ MMAR_0657|M.marinum_M PAEVRLRNLLKPEQFPYTTKTGWVYDSGDYESTMRQAMDMIGYDALRAEQ MUL_0115|M.ulcerans_Agy99 PAELRLRNLLKPEQFPYTTKTGWVYDSGDYESTMRQAMDMIGGDALRAEQ TH_0176|M.thermoresistible__bu PAELRLRNLLKPDQFPYTSKTGWVYDSGDYETTMRKAMAMVGYDELRAEQ Mflv_1573|M.gilvum_PYR-GCK PVELRRINILRGDEMPFFNPNGMPYDNCAPADTFEQAVKILDHEGFRKEQ Mvan_5183|M.vanbaalenii_PYR-1 PVELRRINILRGDEMPFFNPNGMPYDNCAPADTFEQAVKILDHEGFRKEQ MSMEG_2949|M.smegmatis_MC2_155 PAEVRRRNLLPTSAFPHRMPSGYQIDSGDYRAVLDRVIDISGYTGTHQQP MAB_2925c|M.abscessus_ATCC_199 PFEFRRRNVIVPGDS--FVSWEVEEDDLAFGSYGLDQCLDLAQDALARGA * *.* *:: *. Mb0380c|M.bovis_AF2122/97 KQRRARGELMGIGMSFFTEAVGAGPRKDMD--ILGLGMADGCELRVHPTG Rv0373c|M.tuberculosis_H37Rv KQRRARGELMGIGMSFFTEAVGAGPRKDMD--ILGLGMADGCELRVHPTG MMAR_0657|M.marinum_M KEKRDRGELMGIGISFFTEAVGAGPRKDMD--ILGLGMADGCELRVHPTG MUL_0115|M.ulcerans_Agy99 KEKRDRGELMGIGISFFTEAVGAGPRKDMD--ILGLGMADGCELRVHPTG TH_0176|M.thermoresistible__bu AERRRRGELMGIGMSFFTEAVGAGPRKDMD--ILGLGMADGCELRVHPTG Mflv_1573|M.gilvum_PYR-GCK AEALAEGRYIGLGFSAYIEPTGAATGN---------LATEGATVRMESTG Mvan_5183|M.vanbaalenii_PYR-1 ADALAEGRYIGLGFSAYIEPTGAATGN---------LATEGATIRMESTG MSMEG_2949|M.smegmatis_MC2_155 SSATVR-RGVGISFEITPEGGGHASGRLAPNVTPTVAAAESATVRLDRDG MAB_2925c|M.abscessus_ATCC_199 ADPARNGSDLPAGWKVGEGMAIAMIATVPP-----RGHVADARAELDARG . . : . . . .. .:. * Mb0380c|M.bovis_AF2122/97 KAVLRLSVQTQGQGHETTFAQIVAEELGIAPDDIEVVHGDTDQTPFGLGT Rv0373c|M.tuberculosis_H37Rv KAVLRLSVQTQGQGHETTFAQIVAEELGIAPDDIEVVHGDTDQTPFGLGT MMAR_0657|M.marinum_M KAVVRLSVQTQGQGHETTFAQIVAEELGIPPDDIDVVHGDTDQTPFGLGT MUL_0115|M.ulcerans_Agy99 KAVVRLSVQTQGQGHETTFAQIVAEELGIPTDDIDVAHGDTDQTPFGLGT TH_0176|M.thermoresistible__bu KAVVRLSVQTQGQGHETTFAQIVAEELGIPPDDIEVVHGDTDQTPFGLGT Mflv_1573|M.gilvum_PYR-GCK KINVYVNGGSAGNSIETTVVQLTADALGANIDDVATIQGDTAVTPYGAGT Mvan_5183|M.vanbaalenii_PYR-1 KINVYVNGGSAGNSIETTVVQLTADALGANIEDVATIQGDTAVTPYGAGT MSMEG_2949|M.smegmatis_MC2_155 HVTVLSGVTNPGGGNDTALARLAAETLGTTTENVTVVQGDTSLCPPGTGN MAB_2925c|M.abscessus_ATCC_199 RYRISVGSAEFGNGTTTVHAQLAAGVLGCAPDQVYIHQADTDAVSHDTGA : : . * . *. .::.* ** ::: :.** . . * Mb0380c|M.bovis_AF2122/97 YGSRSTPVSGGAAALVARKVRDKAKIIASGMLEVSVADLQWEKGKFHVKG Rv0373c|M.tuberculosis_H37Rv YGSRSTPVSGGAAALVARKVRDKAKIIASGMLEVSVADLQWEKGKFHVKG MMAR_0657|M.marinum_M YGSRSTPVSGAAAALVARKVRDKAKIIASGMLEVSVADLEWEKGSFHVKG MUL_0115|M.ulcerans_Agy99 YGSRSTPVSGAAAALVARKVRDKAKIIASGMLEVSVADLEWEKGSFHVKG TH_0176|M.thermoresistible__bu YGSRSTPVSGAAAALVARKVRDKAKIIASGMLEASIADLEWEKGSFRVKG Mflv_1573|M.gilvum_PYR-GCK QGSRSAPMTAGAVNEAGAILRTQIIAIAAQILGVEAAEIELANSRASVRS Mvan_5183|M.vanbaalenii_PYR-1 QGSRSAPMTAGAVNEAGAILRRQIIAIGAQILGVEESEIELANSRAGVRN MSMEG_2949|M.smegmatis_MC2_155 ASSRGVAVGGAAVVLAARDMADKLRRTAAATLGCAPHEVTLADDAAHAAS MAB_2925c|M.abscessus_ATCC_199 FGSAGTTVAGLAVYRAAELLRDQIIRFAATKLAVPQSRCVLEPDGVRAGA .* ...: . *. .. : : .: * . . Mb0380c|M.bovis_AF2122/97 DPSAAVTIADIAMRAHGAGDLPEGIEGGLDAEVCYN-PSNLTYPYGAYFC Rv0373c|M.tuberculosis_H37Rv DPSAAVTIADIAMRAHGAGDLPEGIEGGLDAEVCYN-PSNLTYPYGAYFC MMAR_0657|M.marinum_M DPSASVTIADIAMRAHGAGDLPEGIEGGLDAEVCYN-PSNLTYPYGAYFC MUL_0115|M.ulcerans_Agy99 DPSASVTIADIAMRAHGAGDLPEGIEGGLDAEVCYN-PSNLTYPYGAYFC TH_0176|M.thermoresistible__bu DPSASVTIQDIAMRAHGAGDLPDGIEGGLDAQICYN-PSNLTYPYGAYFC Mflv_1573|M.gilvum_PYR-GCK DPEKSVSFADIAYRSYYDPGQLGGVSPTLEATARFNSQAMIHWANATHVC Mvan_5183|M.vanbaalenii_PYR-1 DPERSVSFADIAYRSYYDPAQLGGVSPTLEATARFNSQAMIHWANATHVC MSMEG_2949|M.smegmatis_MC2_155 GASIPLRNLCARAAECGELSYTRSYRPTPPDDPAYR-YSYPYFSSGAYVA MAB_2925c|M.abscessus_ATCC_199 DLLGLTEIAASAPEPLSAVGHHEGTP----RSVAFN----------VQAF . . :. . Mb0380c|M.bovis_AF2122/97 VVDIDPGTAVVKVRRFLAVDDCGTRINPMIIEGQVHGGIVDGIGMALMEM Rv0373c|M.tuberculosis_H37Rv VVDIDPGTAVVKVRRFLAVDDCGTRINPMIIEGQVHGGIVDGIGMALMEM MMAR_0657|M.marinum_M VVDVDPGTGVVKVRRFLAVDDCGTRINPMIIEGQVHGGIVDGIGMALMEM MUL_0115|M.ulcerans_Agy99 VVDVDPGTGVVKVRRFLAVDDAGTRINPMIIEGQVHGGIVDGIGMALMEM TH_0176|M.thermoresistible__bu VVDVDPGTAVVKVRRFLAVDDCGTRINPMIIEGQVHGGIVDGIGMALMQM Mflv_1573|M.gilvum_PYR-GCK TCEVDVETGHVTLTRYIVSEDVGPMINPNIVEGQVAGGTVQGIGGALLEK Mvan_5183|M.vanbaalenii_PYR-1 TCEVDVETGQVTLTRYIVSEDVGPMINPNIVEGQVAGGTVQGIGGALLEK MSMEG_2949|M.smegmatis_MC2_155 EVDVDTATGVVKVHAITAVHDCGRVVEPVLVEGQLQGAIAMGIGLALYED MAB_2925c|M.abscessus_ATCC_199 RVAVRPQTGTVRILQSVQTADAGVVVNPQQCRGQVEGGVAQAIGSALYEE : *. * : * * ::* .**: *. . .** ** : Mb0380c|M.bovis_AF2122/97 IAFDEDGNCLGGSLMDYLIPTALEVPHLETGHTVTPSPHHPIGAKGIGES Rv0373c|M.tuberculosis_H37Rv IAFDEDGNCLGGSLMDYLIPTALEVPHLETGHTVTPSPHHPIGAKGIGES MMAR_0657|M.marinum_M IAFDEDGNCLGGSLMDYLIPTALEVPHLETGHTVTPSPHHPIGAKGIGES MUL_0115|M.ulcerans_Agy99 IAFDEDGNCLGGSLMDYLIPTALEVPHLETGHTVTPSPHHPIGAKGIGES TH_0176|M.thermoresistible__bu IGFDEDGNCLGGSLMDYLIPTAMEVPTLETGFTVTPSPHHPIGAKGIGES Mflv_1573|M.gilvum_PYR-GCK LAYDDDGNPVASTFVDYLLPTATEVPPIEFGHVEIPGPG-VGGYKGAGEG Mvan_5183|M.vanbaalenii_PYR-1 LAYDDAGNPVASTFVDYLLPTATEVPPIEFGHVEIPGPG-VGGYKGAGEG MSMEG_2949|M.smegmatis_MC2_155 NRFEADGAPATRTFKEYMVPRANDLPDFVIRHHETPAPHTLLGAKGAGEA MAB_2925c|M.abscessus_ATCC_199 ILVH-DGFVSTTALRNYHIPRLVDVPDTEVYFADTYDTFGPLGAKSMSES . * :: :* :* ::* . . * *. .*. Mb0380c|M.bovis_AF2122/97 ATVGSPPAVVNAVVDALAPFG-------VRHADMPLTPSRVWEAMQGRAT Rv0373c|M.tuberculosis_H37Rv ATVGSPPAVVNAVVDALAPFG-------VRHADMPLTPSRVWEAMQGRAT MMAR_0657|M.marinum_M ATVGSPPAVVNAVVDALAPYG-------VRHADMPLTPSRVWEAMQGRAT MUL_0115|M.ulcerans_Agy99 ATVGSPPAVVNAVVDALAPYG-------VRHADMPLTPSRVWEAMQGRAT TH_0176|M.thermoresistible__bu ATVGSPPAVVNAVVDALAPFG-------VRHVDMPLTPSRVWEAMQGRAQ Mflv_1573|M.gilvum_PYR-GCK GAIGSPPAVINAVNDALAPLG-------VTLTQLPATPATIVELIDAASR Mvan_5183|M.vanbaalenii_PYR-1 GAIGSPPAVINAINDALAPLG-------VTLTQLPATPATIVELIERAG- MSMEG_2949|M.smegmatis_MC2_155 GVGGALAAVANAIDDALQGAQHGAGEPIATVTSVPLDPPTVLSLIPEPRG MAB_2925c|M.abscessus_ATCC_199 PYNPVAPALANAIRDAVG----------VRVYRLPMNAARVWRVINDSGG .*: **: **: . :* .. : : Mb0380c|M.bovis_AF2122/97 PPI- Rv0373c|M.tuberculosis_H37Rv PPI- MMAR_0657|M.marinum_M PPI- MUL_0115|M.ulcerans_Agy99 PPI- TH_0176|M.thermoresistible__bu PSI- Mflv_1573|M.gilvum_PYR-GCK KDH- Mvan_5183|M.vanbaalenii_PYR-1 KDH- MSMEG_2949|M.smegmatis_MC2_155 LG-- MAB_2925c|M.abscessus_ATCC_199 GESS