For questions or suggestions e-mail us at: ioerger@cs.tamu.edu
MRFTVNGADLDATPAAGQCLRTFLREHGHFEVKMGCDAGDCGACSVLVDGAAVHSCVFPAFRAAGRTVTT VAGLGTPDDLHPMQRRFAEAAAFQCGFCTAGLVVTASTFGDDELANLPQHLKGNLCRCTGYRAILDALEG KVNVEKPSGSDAGRSIGAPAALRVVTGTEPYTTDHAPAGLLHLAVLGSPLAHARITSIDTTAAATIPGVH LILTHHDSSAVAFSTARHEMRTDDPDDTYVLDRTVRFIGQRVAAVVADSVAVAEKACRAIQIEYEELPAV FDPEQARAARRGALARRQGRPGPHRRPGAQRGRRITWRHRRCRSRRCRRGGLRRSGGARTVADRPSAAGP PRNPWLHRVAGQPRATGDPHQLPDTVFGPRRTVPRLRAGPRPGARFHQAGRRRIRRQTGDAHRGPGDVGR AETGRPVRYEFTRVDEFVRATCRHPYRIDVTVAADGDGVLTALAVDALMDAGAYGNHTRGVLFHGCGESV SVYRCANKRIDAEAVYTNNVPSGAFRGYGVGQMVFAVESALDDLAQRLGIDAFEFRRRNVVVPGDPFVDA HAGENDLTFGSYGLDQCLDLAQDALRRGGRPAPDGAGWRVGEGMALAMIATLPPGGHFASADISVDDAGV YTLCVGTSEFGNGTTTVHAQLTATALGTTSDRIVIRQSDTDVVEHDTGAFGSAGTVIAGRAALGAAQQLR SRIIAAAAEVAGASPADCVLGPHGVRCGQQLVGFGQLPTPLTGQGSQDGTPRSVSFNAHAVRVAVNTDTG QVEILQSVQAADAGVVLNPEQCRGQVEGSVAQAIGSALYEDLQIGPDGRVLTQTLRDYHIPQFVDVPLTE VYFADTFDELGPLGAKSMAESPYNPMAPALANAIARACGARVTRLPMTAARVWRAINSAE
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. ulcerans Agy99 | MUL_0459 | - | - | 100% (900) | carbon monoxide dehydrogenase |
| M. ulcerans Agy99 | MUL_0588 | coxL_2 | 3e-35 | 31.16% (475) | aerobic-type carbon monoxide dehydrogenase, CoxL_2 |
| M. ulcerans Agy99 | MUL_0115 | coxL | 1e-34 | 26.78% (519) | carbon monoxyde dehydrogenase (large chain), CoxL |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb0380c | - | 2e-31 | 25.64% (511) | carbon monoxyde dehydrogenase large subunit |
| M. gilvum PYR-GCK | Mflv_0284 | - | 2e-33 | 28.63% (475) | aldehyde oxidase and xanthine dehydrogenase, molybdopterin |
| M. tuberculosis H37Rv | Rv0373c | - | 2e-31 | 25.64% (511) | carbon monoxyde dehydrogenase large subunit |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | MAB_2925c | - | 0.0 | 56.73% (929) | xanthine dehydrogenase family protein |
| M. marinum M | MMAR_4945 | - | 0.0 | 85.65% (913) | carbon monoxide dehydrogenase |
| M. avium 104 | - | - | - | - | - |
| M. smegmatis MC2 155 | MSMEG_1291 | - | 0.0 | 71.52% (474) | putative oxidoreductase |
| M. thermoresistible (build 8) | TH_0176 | - | 2e-34 | 27.13% (516) | PROBABLE CARBON MONOXYDE DEHYDROGENASE (LARGE CHAIN) |
| M. vanbaalenii PYR-1 | Mvan_5281 | - | 0.0 | 72.12% (477) | aldehyde oxidase and xanthine dehydrogenase, molybdopterin |
CLUSTAL 2.0.9 multiple sequence alignment
MUL_0459|M.ulcerans_Agy99 MRFTVNGADLDATPAAGQCLRTFLREHGHFEVKMGCDAGDCGACSVLVDG
MMAR_4945|M.marinum_M MRFTVNGADLDATPAAGQCLRTFLREHGHFEVKMGCDAGDCGACSVLVDG
MSMEG_1291|M.smegmatis_MC2_155 MSVRVNGKPVSGAPQPGQCLRTFLRDHGHFEVKKGCDAGDCGACSVLIDD
Mvan_5281|M.vanbaalenii_PYR-1 MRITVNGTDRTDDPRPGQCLRTFLRDLGHVEVKKGCDAGDCGACSVLVDG
MAB_2925c|M.abscessus_ATCC_199 --MKVNGKLIDASPRPGQCLRTFLREHGHVEVKKGCDAGDCGACTVLVDG
Mb0380c|M.bovis_AF2122/97 --------------------------------------------------
Rv0373c|M.tuberculosis_H37Rv --------------------------------------------------
TH_0176|M.thermoresistible__bu --------------------------------------------------
Mflv_0284|M.gilvum_PYR-GCK --------------------------------------------------
MUL_0459|M.ulcerans_Agy99 AAVHSCVFPAFRAAGRTVTTVAGLGTPDDLHPMQRRFAEAAAFQCGFCTA
MMAR_4945|M.marinum_M AAVHSCVFPAFRAAGRTVTTVAGLGTPDDLHPMQRRFAEAAAFQCGFCTA
MSMEG_1291|M.smegmatis_MC2_155 VAVHSCVYPAFRADGRDVKTVAGLGTSEDLHPMQRRFVEAAGFQCGFCTA
Mvan_5281|M.vanbaalenii_PYR-1 AAVHSCVYPAFRADGRTVTTVAGLGTPKDLHPMQRRFVEAAGFQCGFCTA
MAB_2925c|M.abscessus_ATCC_199 ASQHSCIVPAHRVTDAEIHTVRSLAGEHDLHPMQRGFIDHAGFQCGFCTA
Mb0380c|M.bovis_AF2122/97 --------------------------------------------------
Rv0373c|M.tuberculosis_H37Rv --------------------------------------------------
TH_0176|M.thermoresistible__bu --------------------------------------------------
Mflv_0284|M.gilvum_PYR-GCK --------------------------------------------------
MUL_0459|M.ulcerans_Agy99 GLVVTASTFGDDELANLPQHLKGNLCRCTGYRAILDALEGKVNVEKPSGS
MMAR_4945|M.marinum_M GLVVTASTFGDDELANLPQHLKGNLCRCTGYRAILDALEGKVNVEKPSGS
MSMEG_1291|M.smegmatis_MC2_155 GMITTASTFTEEQRANLAEHLKGNLCRCTGYRSITDALDGVSNVEKSGGT
Mvan_5281|M.vanbaalenii_PYR-1 GMVTTASALTADQLEHLPQHLKGNLCRCTGYRAITDAIAGVVNTEKSGGS
MAB_2925c|M.abscessus_ATCC_199 GMVLTAATLTGDQTEDLGNALKGNLCRCTGYRPIRDAVCGVVPPRG----
Mb0380c|M.bovis_AF2122/97 ------MTTIESRPPS-PEDLADNAQQPCGHGRMMRKED-----------
Rv0373c|M.tuberculosis_H37Rv ------MTTIESRPPS-PEDLADNAQQPCGHGRMMRKED-----------
TH_0176|M.thermoresistible__bu ------MTTLESNPAARPDDFENNDQKPCGHGRMLRKED-----------
Mflv_0284|M.gilvum_PYR-GCK ------MTMLEPRAIGAPTARRDGQAK-----------------------
: . .. :
MUL_0459|M.ulcerans_Agy99 DAGRSIGAPAALRVVTGTEPYTTDHAPAGLLHLAVLGSPLAHARITSIDT
MMAR_4945|M.marinum_M DAGRSIGAPAALRVVTGTEPYTTDHAPAGLLHLAVLGSPLAHARITSIDT
MSMEG_1291|M.smegmatis_MC2_155 TA--SVGAPAAVRVATGTEPYTMDHTPEGLLHLAVLGSPVAHARIVAIDT
Mvan_5281|M.vanbaalenii_PYR-1 DVGRSIGAPAGVRVVTGTEEYTMDDTPVGLLHMAVLASPVPHARIRSIDT
MAB_2925c|M.abscessus_ATCC_199 ----SVSAPAAARVVTGTEPYTMDELPAGVGHVAVLGSPHPSARITRIDT
Mb0380c|M.bovis_AF2122/97 -----------PRFIRGRGTYVDDVALPGMLHLAILRSPYAHARIVRIDV
Rv0373c|M.tuberculosis_H37Rv -----------PRFIRGRGTYVDDVALPGMLHLAILRSPYAHARIVRIDV
TH_0176|M.thermoresistible__bu -----------PRFIRGRGRYVDDVQLPGMLHLAILRSPYAHARIAGIDT
Mflv_0284|M.gilvum_PYR-GCK --------------VTGAAAYAYEQQVDSPAYLHPVQATIARGRVIAMDT
* *. : . :: : :. . .*: :*.
MUL_0459|M.ulcerans_Agy99 TAAATIPGVHLILTHHDSSAVAFSTARHEMRTDDPDDTYVLDRTVRFIGQ
MMAR_4945|M.marinum_M TAAAAIPGVHLILTHHDSPAVAFSTARHEMRTDDPDDTYVLDRTVRFIGQ
MSMEG_1291|M.smegmatis_MC2_155 SAAEAVPGVRLVLTYLDAPRVAFSTARHEIREDDPDDTYVLDSTVRFVGQ
Mvan_5281|M.vanbaalenii_PYR-1 AAAESIPGVRLVLTHRDSPAVRFSTARHESRDDDPDDTVILDDTVRFVGQ
MAB_2925c|M.abscessus_ATCC_199 DRARLLPGVRAVLCYRDDPGVPFSTARHHERTDDPDDTLVFDRVLRFAGQ
Mb0380c|M.bovis_AF2122/97 TAAQAHPKVKAVVTGADLAAKGLAWMPTLAN---DVQAVLATDKTRFQGQ
Rv0373c|M.tuberculosis_H37Rv TAAQAHPKVKAVVTGADLAAKGLAWMPTLAN---DVQAVLATDKTRFQGQ
TH_0176|M.thermoresistible__bu SAAQAHPKVKAVVTGADLAEKGLAWMPTLSN---DVQAVLATDKVRFQGQ
Mflv_0284|M.gilvum_PYR-GCK NLARAVDGVLDILTVSDAPKLADASD--------GELAILQDATVHFRGQ
* * :: * . : : : :* **
MUL_0459|M.ulcerans_Agy99 RVAAVVADSVAVAEKACRAIQIEYEELPAVFDPEQARAARRGALARRQGR
MMAR_4945|M.marinum_M RVAAVVADSVAVAEKACRAIQIEYEELPAVFDPEQARAP--GAVLLHADK
MSMEG_1291|M.smegmatis_MC2_155 RVAAVVADSVAAAETACRAIAVEYEQLPAVFDPDEARSP--GAPLLHADK
Mvan_5281|M.vanbaalenii_PYR-1 RVAAVVADSVAVAEAACRAIVVDYEPRPAVFDPDTARRP--GAPLLHADK
MAB_2925c|M.abscessus_ATCC_199 RVAAVVADTPAIAHRALEHIDVEYEVLPAVFDPEMAQLP--GAHLVHGDK
Mb0380c|M.bovis_AF2122/97 EVASVVAEDRYSARDACELVDVDYEPRDPVVDARTALDP--SAPVIRTDL
Rv0373c|M.tuberculosis_H37Rv EVAFVVAEDRYSARDACELVDVDYEPRDPVVDARTALDP--SAPVIRTDL
TH_0176|M.thermoresistible__bu EVAFVVAEDHYSARDALELIDVDYDPLDPVVDVRRALEP--DAPVIRTDL
Mflv_0284|M.gilvum_PYR-GCK LIGGVVAETAEIAREAAALVHVEYQEKEHDAALRADHPGLYTPESVNPSY
:. ***: *. * : ::*: . . .
MUL_0459|M.ulcerans_Agy99 PGPHRRPGAQRGRRITWRHRRCRSRRCRRGGLRRSGGARTVADRPSAAGP
MMAR_4945|M.marinum_M GGQARIADPARN-VVAELHGGTGDVEAGVAAAEASGGAVVRGRWQTARVQ
MSMEG_1291|M.smegmatis_MC2_155 GPDARIADPSRN-IVAELHGGIGDVQQAVAAAHT----VVRGRYHTQRVQ
Mvan_5281|M.vanbaalenii_PYR-1 GPESRIADPSRN-LVAELHGEVGDVAEGVRAAEAGGGAVVRGSWRTQRVQ
MAB_2925c|M.abscessus_ATCC_199 GLGARIADPARN-LVAEVHGEVGDVAAALARARESG-AVVTGSWQTARVQ
Mb0380c|M.bovis_AF2122/97 EGKSD----------NHIFDWETGDAAATEAVFAKADVVVQQEIVYPRVH
Rv0373c|M.tuberculosis_H37Rv EGKSD----------NHIFDWETGDAAATEAVFAKADVVVQQEIVYPRVH
TH_0176|M.thermoresistible__bu DGKTD----------NHCFDWETGDPAATEAAFAKADVVVEQEIVYPRVH
Mflv_0284|M.gilvum_PYR-GCK PPDSD--------------------QGDVESAFPAAEFTVDQTYRTPTEH
.
MUL_0459|M.ulcerans_Agy99 PRNPWLHRVAGQPR---ATG--DPHQLPDTVFGPRRTVPRLRAGPR-PGA
MMAR_4945|M.marinum_M PAHLETHGCTGWRD---SRGRLVIRTSSQTPFLVRDELCHVFGLDRDQVH
MSMEG_1291|M.smegmatis_MC2_155 HVHLETHGCTGWVD---EDGRLTIRTSTQVPFLVRDELCRIFRLDRDVVR
Mvan_5281|M.vanbaalenii_PYR-1 HAHLETHGCTGWRD---DAGRLVIRTSSQVPFLVRDELCHIFGLDTDEVR
MAB_2925c|M.abscessus_ATCC_199 HVHLETHGSVGWQD---ERGRYVLRTSSQVPFLVRDELCHVFGLAREQVR
Mb0380c|M.bovis_AF2122/97 PAPMETCGAVADLDP--VTGKLTLWTTSQAPHAHRTLYALVAGLPEHKIR
Rv0373c|M.tuberculosis_H37Rv PAPMETCGAVADLDP--VTGKLTLWTTSQAPHAHRTLYALVAGLPEHKIR
TH_0176|M.thermoresistible__bu PAPMETCGAVADLDP--VTGKLTLWSTSQAPHAHRTLYALVAGLPEHKIR
Mflv_0284|M.gilvum_PYR-GCK NNPMEPHACVAQWTVRDGTPAVTMYDSTQGVHVVRKTLAPIFGLEPEQMR
.. .: . * :
MUL_0459|M.ulcerans_Agy99 RFHQAGRRRIRRQTGDAHRGP-GDVGRAETG-RPVRYEFTRVDEFVRATC
MMAR_4945|M.marinum_M VFTKRVGGGFGGKQEMLTEDL-VTLAVLRLG-RPVRYEFTRVDEFVRATC
MSMEG_1291|M.smegmatis_MC2_155 VFATRVGGGFGAKQEMLVEDL-VALAVLRLG-RPVRYEFSRSDEFTMAPC
Mvan_5281|M.vanbaalenii_PYR-1 VFTRRVGGGFGGKQEMLAEDL-VALAVLRLG-APVRYEFSRTDEFTVAPC
MAB_2925c|M.abscessus_ATCC_199 VFAPRVGGGFGAKQEMLTEDL-VLLAVRVTG-APVVYEFTRSDQFTIAPC
Mb0380c|M.bovis_AF2122/97 VISPDIGGGFGNKVPIYPGYVCAIVASLLLD-KPVKWMEDRSENLTSTGF
Rv0373c|M.tuberculosis_H37Rv VISPDIGGGFGNKVPIYPGYVCAIVASLLLD-KPVKWMEDRSENLTSTGF
TH_0176|M.thermoresistible__bu VIAPDIGGGFGNKVPIYPGYVCAIVGSLLLG-KPVKWVEDRSENLTSTGF
Mflv_0284|M.gilvum_PYR-GCK VVAPHVGGGFGSKGAPHAHDVLTVMAAQRAGGRPVKLALTRQQMFSLVGY
. : : :. . ** * : : .
MUL_0459|M.ulcerans_Agy99 RHPYRIDVTVAADGDGVLTALAVDALMDAGAYGNHTRGVLFHG--CGESV
MMAR_4945|M.marinum_M RHPYRIDVTVAADGDGVLTALAVDALMDAGAYGNHTRGVLFHG--CGESV
MSMEG_1291|M.smegmatis_MC2_155 RHPFRVDVTVAADEDGTLTALAVDVLTDAGAYGNHSPGVMFHG--CAESV
Mvan_5281|M.vanbaalenii_PYR-1 RHPFRVEVTVAAGRDGRLTALAVDALVDAGAYGNHSPGVMFHG--CGESV
MAB_2925c|M.abscessus_ATCC_199 RHPMRVNVTAAADGDGVLTALAVDVLSDAGAYGNHSVGVMFHG--CNESM
Mb0380c|M.bovis_AF2122/97 ARDYIMVGEIAANRDGKILAIRSNVLADHGAFNAQAAPAKYPAGFFGVFT
Rv0373c|M.tuberculosis_H37Rv ARDYIMVGEIAANRDGKILAIRSNVLADHGAFNAQAAPAKYPAGFFGVFT
TH_0176|M.thermoresistible__bu ARDYIMVGEIAATRDGRILAIRSHVLADHGAFNGTAAPVKYPAGFFGVFT
Mflv_0284|M.gilvum_PYR-GCK RTPTIQRVRLGADRDGRLTALVHDAIGQTATVKEFAEQTAVTS------R
.* ** : *: ..: : .: : . .
MUL_0459|M.ulcerans_Agy99 SVYRCANKRIDAEAVYTNNVPSGAFRG--YGVGQMVFAVESALDDLAQRL
MMAR_4945|M.marinum_M SVYRCANKRIDAEAVYTNNVPSGAFRG--YGVGQMVFAVESALDDLAQRL
MSMEG_1291|M.smegmatis_MC2_155 AVYRCANKRIDAQSVYTNNLPSGAFRG--YGLGQVIFAIESALDELAQRL
Mvan_5281|M.vanbaalenii_PYR-1 AVYRSPNKRVDAEAVYTNNLPSGAFRG--YGLGQISFAVESAIDELAARL
MAB_2925c|M.abscessus_ATCC_199 AQYRCANKRVDAQAVYTNNIPSGAFRG--YGLGQVLFGIESALDELARNL
Mb0380c|M.bovis_AF2122/97 GSYDIEAAYCHMTAVYTNKAPGGVAYACSFRITEAVYFVERLVDCLAFEL
Rv0373c|M.tuberculosis_H37Rv GSYDIEAAYCHMTAVYTNKAPGGVAYACSFRITEAVYFVERLVDCLAFEL
TH_0176|M.thermoresistible__bu GSYDLEAAYCHMTAVYTNKAPGGVAYACSFRITEAVYLVERLVDCLAHEL
Mflv_0284|M.gilvum_PYR-GCK KMYAAANRRTSHRLAALDVPVPFWMRAP--GECPGTYAAEVAMDELAVAA
* . : . : * :* **
MUL_0459|M.ulcerans_Agy99 GIDAFEFRRRNVVVPGDPFVDAHA--GENDLTFGSYGLDQCLDLAQDALR
MMAR_4945|M.marinum_M GIDAFEFRRRNVVVPGDPFVDAHA--GENDLTFGSYGLDQCLDLAQDALR
MSMEG_1291|M.smegmatis_MC2_155 GIDPFELRRRNVVRPGDRLIDAHE--PED-LLFGSYGLDQCLDLTQNALA
Mvan_5281|M.vanbaalenii_PYR-1 GIDPFEFRRRNVVVPGDTFVDSHV--LEDDLTFGSYGLDQCLDLAEAALR
MAB_2925c|M.abscessus_ATCC_199 GIDPFEFRRRNVIVPGDSFVSWEV--EEDDLAFGSYGLDQCLDLAQDALA
Mb0380c|M.bovis_AF2122/97 KMDPAELRLRNLLRPNQFPYQSKTGWVYDSGDYETTMRKAMNMIGYEALR
Rv0373c|M.tuberculosis_H37Rv KMDPAELRLRNLLRPNQFPYQSKTGWVYDSGDYETTMRKAMNMIGYEALR
TH_0176|M.thermoresistible__bu EMDPAELRLRNLLKPDQFPYTSKTGWVYDSGDYETTMRKAMAMVGYDELR
Mflv_0284|M.gilvum_PYR-GCK GIDPIQLRIRNDPPTDP----------ETGKPWSGRHLVECLEVGAERFD
:*. ::* ** .. : : :
MUL_0459|M.ulcerans_Agy99 RGGRP-----APDGAGWRVGEGMALAMIATLPPG-------GHFASADIS
MMAR_4945|M.marinum_M RGGRP-----APDGAGWRVGEGMALAMIATLPPG-------GHFGSADIS
MSMEG_1291|M.smegmatis_MC2_155 AGNG------AVAPQGWQVGEGMAVAMIATLPPR-------GHFADATVT
Mvan_5281|M.vanbaalenii_PYR-1 AGNG------ATAPAGWAVGEGMAVAMIATIPPR-------GHFTEVSVS
MAB_2925c|M.abscessus_ATCC_199 RGAADPARNGSDLPAGWKVGEGMAIAMIATVPPR-------GHVADARAE
Mb0380c|M.bovis_AF2122/97 AEQKQR----RARGELMGIGMSFFTEAVGAGPRKDMDILGLGMADGCELR
Rv0373c|M.tuberculosis_H37Rv AEQKQR----RARGELMGIGMSFFTEAVGAGPRKDMDILGLGMADGCELR
TH_0176|M.thermoresistible__bu AEQAER----RRRGELMGIGMSFFTEAVGAGPRKDMDILGLGMADGCELR
Mflv_0284|M.gilvum_PYR-GCK WSSRDPEP-GTRVLGDWLVGTGVASATYPGMAMPG---------NAARIT
:* .. .
MUL_0459|M.ulcerans_Agy99 VDDAGVYTLCVGTSEFGNGTTTVHAQLTATALGTTSDRIVIRQSDTDVVE
MMAR_4945|M.marinum_M VDDAGVYTLCVGTSEFGNGTTTVHAQLTATALGTTSDRIVIRQSDTDVVE
MSMEG_1291|M.smegmatis_MC2_155 LKDDGRYELSVGTAEFGNGTTTVHAQLVATLMNTTVDRVSIRQSDTDAGG
Mvan_5281|M.vanbaalenii_PYR-1 VDADGVYTLDVGTAEFGNGTTTVHVQLAAAELNTVPERIVVRQSDTATTG
MAB_2925c|M.abscessus_ATCC_199 LDARGRYRISVGSAEFGNGTTTVHAQLAAGVLGCAPDQVYIHQADTDAVS
Mb0380c|M.bovis_AF2122/97 VHPTGKAVLRLSVQTQGQGHETTFAQIVAEELGIAPDDIEVVHGDTDQTP
Rv0373c|M.tuberculosis_H37Rv VHPTGKAVLRLSVQTQGQGHETTFAQIVAEELGIAPDDIEVVHGDTDQTP
TH_0176|M.thermoresistible__bu VHPTGKAVVRLSVQTQGQGHETTFAQIVAEELGIPPDDIEVVHGDTDQTP
Mflv_0284|M.gilvum_PYR-GCK YSAEGHYDVHIGAADIGTGTWTTLSQIAADALDCDLAAITLQIGDTDLPA
* : :. * * *. *:.* :. : : .**
MUL_0459|M.ulcerans_Agy99 HDTGAFGSAGTVIAGRAALGAAQQLRSRIIAAAAEVAGASPADCVLGPHG
MMAR_4945|M.marinum_M HDTGAFGSAGTVIAGRAALAAAQQLRSRIIAAAAEVAGASPADCVLGPHG
MSMEG_1291|M.smegmatis_MC2_155 YDTGAFGSAGIVVAGRAVHQACVALRATIERAAAELTGVDAVSCVVGPHG
Mvan_5281|M.vanbaalenii_PYR-1 YDTGAFGSAGTVVAGLAILAASRELRTALVTAAAELTGAAPSSCVLGRNG
MAB_2925c|M.abscessus_ATCC_199 HDTGAFGSAGTTVAGLAVYRAAELLRDQIIRFAATKLAVPQSRCVLEPDG
Mb0380c|M.bovis_AF2122/97 FGLGTYGSRSTPVSGGAAALVARKVRDKAKIIASGMLEVSVADLQWEKGK
Rv0373c|M.tuberculosis_H37Rv FGLGTYGSRSTPVSGGAAALVARKVRDKAKIIASGMLEVSVADLQWEKGK
TH_0176|M.thermoresistible__bu FGLGTYGSRSTPVSGAAAALVARKVRDKAKIIASGMLEASIADLEWEKGS
Mflv_0284|M.gilvum_PYR-GCK ASVAGGSSGMTSWGTTIVLAAQQFRRDHGNPPVIGATTVT----------
. . .* . . * . .
MUL_0459|M.ulcerans_Agy99 VRCG-------------QQLVGFGQLPT----PLTGQGSQDGTPRSVSFN
MMAR_4945|M.marinum_M VQCG-------------QQLVGFGQLPT----PLTGQGSQDGTPRSVSFN
MSMEG_1291|M.smegmatis_MC2_155 VQCR-------------DRFVPFTELAL----PLTATGHHDGTPRSVAFN
Mvan_5281|M.vanbaalenii_PYR-1 VQCD-------------ARLVDFGSLPT----PMNRTARHDGTPRSVAFN
MAB_2925c|M.abscessus_ATCC_199 VRAG-------------ADLLGLTEIAASAPEPLSAVGHHEGTPRSVAFN
Mb0380c|M.bovis_AF2122/97 FHVKGDPSAAVTIADIAMRAHGAGDLPEGIEGGLDAEVCYNPSNLTYPYG
Rv0373c|M.tuberculosis_H37Rv FHVKGDPSAAVTIADIAMRAHGAGDLPEGIEGGLDAEVCYNPSNLTYPYG
TH_0176|M.thermoresistible__bu FRVKGDPSASVTIQDIAMRAHGAGDLPDGIEGGLDAQICYNPSNLTYPYG
Mflv_0284|M.gilvum_PYR-GCK ----------------------------------EAPDPENDEVTVQSFG
: .:.
MUL_0459|M.ulcerans_Agy99 AHAVRVAVNTDTGQVEILQSVQAADAGVVLNPEQCRGQVEGSVAQAIGSA
MMAR_4945|M.marinum_M VHAFRVAVNTDTGQVEILQSVQAADAGVVLNPEQCRGQVEGSVAQAIGSA
MSMEG_1291|M.smegmatis_MC2_155 VQGFRVAVNPETGEVRILQSVQAADAGVVLNPEQCRGQVEGGVAQAIGSA
Mvan_5281|M.vanbaalenii_PYR-1 VHAFRVAVDTETGEVRILQSIQAADAGVVINPQQCRGQVEGGVAQAIGSA
MAB_2925c|M.abscessus_ATCC_199 VQAFRVAVRPQTGTVRILQSVQTADAGVVVNPQQCRGQVEGGVAQAIGSA
Mb0380c|M.bovis_AF2122/97 AYFCVVDIDPGTAVVKVRRFLAVDDCGTRINPMIIEGQVHGGIVDGIGMA
Rv0373c|M.tuberculosis_H37Rv AYFCVVDIDPGTAVVKVRRFLAVDDCGTRINPMIIEGQVHGGIVDGIGMA
TH_0176|M.thermoresistible__bu AYFCVVDVDPGTAVVKVRRFLAVDDCGTRINPMIIEGQVHGGIVDGIGMA
Mflv_0284|M.gilvum_PYR-GCK AHFVEAHVNRHTGEIRVPRMLGVFSIGRAINPRTLRSQLIGGMTMGLSMA
. . : *. :.: : : . . * :** ..*: *.:. .:. *
MUL_0459|M.ulcerans_Agy99 LYEDLQIGP-DGRVLTQTLRDYHIPQFVDVPLTEVYFADTFDELG-PLGA
MMAR_4945|M.marinum_M LYEDLQIGP-DGRVLTQTLRDYHIPQFVDVPLTEVYFADTFDELG-PLGA
MSMEG_1291|M.smegmatis_MC2_155 LYEEMRVGA-DGRVLTQTLRNYHIPQLADIPQTKVYFADTYDELG-PLGA
Mvan_5281|M.vanbaalenii_PYR-1 LFEEILIGP-DGAVMTKALRDYHIPQVADVPATEVYFADTHDDLG-PLGA
MAB_2925c|M.abscessus_ATCC_199 LYEEILVH--DGFVSTTALRNYHIPRLVDVPDTEVYFADTYDTFG-PLGA
Mb0380c|M.bovis_AF2122/97 LMEMIAFDE-DGNCLGGSLMDYLIPTALEVPHLETGHTVTPSPHH-PIGA
Rv0373c|M.tuberculosis_H37Rv LMEMIAFDE-DGNCLGGSLMDYLIPTALEVPHLETGHTVTPSPHH-PIGA
TH_0176|M.thermoresistible__bu LMQMIGFDE-DGNCLGGSLMDYLIPTAMEVPTLETGFTVTPSPHH-PIGA
Mflv_0284|M.gilvum_PYR-GCK LHEESVRDPRFGHVVTQDFATYHISSHADVVDIDAIWLDEVDEHLNPMGS
* : * : * *. :: .. . *:*:
MUL_0459|M.ulcerans_Agy99 KSMAESPYNPMAPALANAIARACG---ARVTRLPMTAARVWRAINSAE--
MMAR_4945|M.marinum_M KSMAESPYNPVAPALANAIARACG---ARVTRLPMTAARVWRAINSAE--
MSMEG_1291|M.smegmatis_MC2_155 KSMSESPYNPVAPALANAIARAVG---VRPRELPMTPARIWRALQQGRA-
Mvan_5281|M.vanbaalenii_PYR-1 KSMSESPYNPVAPALANAIARACG---ARVCQLPMTPARVWRAVRASR--
MAB_2925c|M.abscessus_ATCC_199 KSMSESPYNPVAPALANAIRDAVG---VRVYRLPMNAARVWRVINDSGGG
Mb0380c|M.bovis_AF2122/97 KGIGESATVGSPPAVVNAVVDALAPFGVRHADMPLTPSRVWEAMQGRATP
Rv0373c|M.tuberculosis_H37Rv KGIGESATVGSPPAVVNAVVDALAPFGVRHADMPLTPSRVWEAMQGRATP
TH_0176|M.thermoresistible__bu KGIGESATVGSPPAVVNAVVDALAPFGVRHVDMPLTPSRVWEAMQGRAQP
Mflv_0284|M.gilvum_PYR-GCK RGAGEIGIVGSAAAVVNAVYHATG---IRVRDLPVTLDKVLAGLP-----
:. .* ..*:.**: * . * :*:. :: :
MUL_0459|M.ulcerans_Agy99 ---
MMAR_4945|M.marinum_M ---
MSMEG_1291|M.smegmatis_MC2_155 ---
Mvan_5281|M.vanbaalenii_PYR-1 ---
MAB_2925c|M.abscessus_ATCC_199 ESS
Mb0380c|M.bovis_AF2122/97 PI-
Rv0373c|M.tuberculosis_H37Rv PI-
TH_0176|M.thermoresistible__bu SI-
Mflv_0284|M.gilvum_PYR-GCK ---