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M. thermoresistible (build 8) TH_1269 (-)

annotation: nicotine dehydrogenase
coordinates: 2421307 - 2423604
length: 766

aa seq not available

Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. thermoresistible (build 8)TH_1269--100% (766)nicotine dehydrogenase
M. thermoresistible (build 8)TH_0176-e-12436.79% (772) PROBABLE CARBON MONOXYDE DEHYDROGENASE (LARGE CHAIN)

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97Mb0380c-1e-12536.98% (776) carbon monoxyde dehydrogenase large subunit
M. gilvum PYR-GCKMflv_1573-0.081.83% (765) carbon-monoxide dehydrogenase (acceptor)
M. tuberculosis H37RvRv0373c-1e-12536.98% (776) carbon monoxyde dehydrogenase large subunit
M. leprae Br4923-----
M. abscessus ATCC 19977MAB_2925c-5e-5428.46% (780) xanthine dehydrogenase family protein
M. marinum MMMAR_0623coxL_30.079.82% (758) aerobic-type carbon monoxide dehydrogenase, CoxL_3
M. avium 104-----
M. smegmatis MC2 155MSMEG_5880-0.083.93% (759) nicotine dehydrogenase
M. ulcerans Agy99MUL_0588coxL_20.079.95% (758) aerobic-type carbon monoxide dehydrogenase, CoxL_2
M. vanbaalenii PYR-1Mvan_5183-0.080.52% (770) carbon-monoxide dehydrogenase (acceptor)

CLUSTAL 2.0.9 multiple sequence alignment


Mb0380c|M.bovis_AF2122/97           --------------------------------------------------
Rv0373c|M.tuberculosis_H37Rv        --------------------------------------------------
TH_1269|M.thermoresistible__bu      --------------------------------------------------
MSMEG_5880|M.smegmatis_MC2_155      --------------------------------------------------
Mflv_1573|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_5183|M.vanbaalenii_PYR-1       --------------------------------------------------
MMAR_0623|M.marinum_M               --------------------------------------------------
MUL_0588|M.ulcerans_Agy99           --------------------------------------------------
MAB_2925c|M.abscessus_ATCC_199      MKVNGKLIDASPRPGQCLRTFLREHGHVEVKKGCDAGDCGACTVLVDGAS
                                                                                      

Mb0380c|M.bovis_AF2122/97           --------------------------------------------------
Rv0373c|M.tuberculosis_H37Rv        --------------------------------------------------
TH_1269|M.thermoresistible__bu      --------------------------------------------------
MSMEG_5880|M.smegmatis_MC2_155      --------------------------------------------------
Mflv_1573|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_5183|M.vanbaalenii_PYR-1       --------------------------------------------------
MMAR_0623|M.marinum_M               --------------------------------------------------
MUL_0588|M.ulcerans_Agy99           --------------------------------------------------
MAB_2925c|M.abscessus_ATCC_199      QHSCIVPAHRVTDAEIHTVRSLAGEHDLHPMQRGFIDHAGFQCGFCTAGM
                                                                                      

Mb0380c|M.bovis_AF2122/97           -MTTIESRPPSPEDLADNAQQPCGHGR------------------MMRKE
Rv0373c|M.tuberculosis_H37Rv        -MTTIESRPPSPEDLADNAQQPCGHGR------------------MMRKE
TH_1269|M.thermoresistible__bu      ---------------------------------------------VPRVE
MSMEG_5880|M.smegmatis_MC2_155      -MTSA---------APETVTTRYAGRR------------------VERVE
Mflv_1573|M.gilvum_PYR-GCK          -MTDADVQ------AVDAVSPRYAGQR------------------VPRVE
Mvan_5183|M.vanbaalenii_PYR-1       -MTDT---------ATNAVTARYAGQR------------------VPRVE
MMAR_0623|M.marinum_M               -MTQD---------MQEAPAPRYAGTR------------------VQRVE
MUL_0588|M.ulcerans_Agy99           -MTQD---------MQEAPAPGYAGTR------------------VPRVE
MAB_2925c|M.abscessus_ATCC_199      VLTAATLTGDQTEDLGNALKGNLCRCTGYRPIRDAVCGVVPPRGSVSAPA
                                                                                 :    

Mb0380c|M.bovis_AF2122/97           DPRFIRGRGTYVDDVALPGMLHLAILRSPYAHARIVRIDVTAAQAHPKVK
Rv0373c|M.tuberculosis_H37Rv        DPRFIRGRGTYVDDVALPGMLHLAILRSPYAHARIVRIDVTAAQAHPKVK
TH_1269|M.thermoresistible__bu      DTRLLTGRGTFVDDIIRPGMLHACFVRSPFARATINGIDASAALAMPGVR
MSMEG_5880|M.smegmatis_MC2_155      DTRLLTGRGTFVDDIVRPGMLHACFVRSPFAHAKINGIDATEALALPGVR
Mflv_1573|M.gilvum_PYR-GCK          DSRLLTGQGRFVDDISRPGMLHACFVRSPFARATIRGIDTSAALALPGVH
Mvan_5183|M.vanbaalenii_PYR-1       DSRLLTGHGRFVDDISRPGMLHACFVRSPFAHATINGVDASAALALPGVH
MMAR_0623|M.marinum_M               DGRLLTGHGSFVDDISRPGMLHACFVRSPFAHARINGIDTATALALPGVH
MUL_0588|M.ulcerans_Agy99           DGRLLTGHGSFVDDISRPGMLHACFVRSPFAHARINGIDTTAALALPGVH
MAB_2925c|M.abscessus_ATCC_199      AARVVTGTEPYTMDELPAGVGHVAVLGSPHPSARITRIDTDRARLLPGVR
                                      *.: *   :. *   .*: * ..: **.. * *  :*.  *   * *:

Mb0380c|M.bovis_AF2122/97           AVVTGADLAAKG-LAWMPTLANDVQAV----LATDKTRFQGQEVASVVAE
Rv0373c|M.tuberculosis_H37Rv        AVVTGADLAAKG-LAWMPTLANDVQAV----LATDKTRFQGQEVAFVVAE
TH_1269|M.thermoresistible__bu      AVFTAADINPEVKEAWHAVAGKDVPDTPRPPLAESEAKFVGDPVALVVAD
MSMEG_5880|M.smegmatis_MC2_155      AVFTAADINPEVKEAWHAVAGRDMPDTPRPPLAEGEVKFVGDPVAIVIAE
Mflv_1573|M.gilvum_PYR-GCK          AVFTASDLNPDVREAWHAVAGKDVPDTPRPPLAEGEVKFVGDPVALVVAD
Mvan_5183|M.vanbaalenii_PYR-1       AVFTAADLNPDVKEAWHAVAGKDVPDTPRPPLAEGEVKFVGDPVALVVAD
MMAR_0623|M.marinum_M               AVFTAADLNADVKEAWHAVAGRDVADTPRPPLAERDAKFVGDPVALVVAE
MUL_0588|M.ulcerans_Agy99           AVFTAADLNADVKEAWHAVAGRDVADTPRPPLAERDAKFVGDPVALVVAE
MAB_2925c|M.abscessus_ATCC_199      AVLCYRDDPGVPFSTARHHERTDDPDD--TLVFDRVLRFAGQRVAAVVAD
                                    **.   *       :       *        :     :* *: ** *:*:

Mb0380c|M.bovis_AF2122/97           DRYSARDACELVDVDYEPRDPVVDARTALDP--------SAPVIRTDLEG
Rv0373c|M.tuberculosis_H37Rv        DRYSARDACELVDVDYEPRDPVVDARTALDP--------SAPVIRTDLEG
TH_1269|M.thermoresistible__bu      SRYIAEDAIELVDVDYEPLPAVADFRQAVN---------SDVVVHEEYPD
MSMEG_5880|M.smegmatis_MC2_155      SRYVAEDAVDLVEVDYEPLPAVVDFRTALT---------SPVAVHDAYPD
Mflv_1573|M.gilvum_PYR-GCK          SRYLAEDAVDLVEVDYEPLPAVADFRKAVGG-----ASAGVPVVHEAYPD
Mvan_5183|M.vanbaalenii_PYR-1       SRYLAEDAVDLVEVDYDPLPAVADFRKAVGG-----AEAGVPVVHAAYPD
MMAR_0623|M.marinum_M               SRYVAEDAIELVDIDYEPLPAITDFTRAQS---------SDVLVHESYPD
MUL_0588|M.ulcerans_Agy99           SRYVAEDAIELVDIDYEPLPAITDFTRAQS---------SDVLVHESYPD
MAB_2925c|M.abscessus_ATCC_199      TPAIAHRALEHIDVEYEVLPAVFDPEMAQLPGAHLVHGDKGLGARIADPA
                                        *. * : ::::*:   .: *   *                :     

Mb0380c|M.bovis_AF2122/97           KSDNHIFDWETGDAAATEAVFAKADVVVQQEIVYPRVHPAPMETCGAVAD
Rv0373c|M.tuberculosis_H37Rv        KSDNHIFDWETGDAAATEAVFAKADVVVQQEIVYPRVHPAPMETCGAVAD
TH_1269|M.thermoresistible__bu      NVAG-----GMAGAPPDEETFANAAHVVSEHIYQHAHVPVPIECRGIVAE
MSMEG_5880|M.smegmatis_MC2_155      NNAG-----GMAGAPPDEETFDSAAHVVKEHVYQQVYVPVPIETRGLVVE
Mflv_1573|M.gilvum_PYR-GCK          NVAG-----GMGGMPPDEELFATAPHVVEQHIYQQMYVPVPMETRGMVVE
Mvan_5183|M.vanbaalenii_PYR-1       NVAG-----GMGGMPPDEEIFATAAHVVEEHIYQQMYVPVPMETRGMVVE
MMAR_0623|M.marinum_M               NVAG-----GLAGAPPDEQTFATSPCVVTENIYQQMYAPVPIETRGLVAE
MUL_0588|M.ulcerans_Agy99           NVAG-----GLAGAPPDEQTFATSPCVVTENIYQQMYAPVPIETRGLVAE
MAB_2925c|M.abscessus_ATCC_199      RNLVAEVHGEVGDVAAALARARESGAVVTGSWQTARVQHVHLETHGSVG-
                                    .          .. ..       :  **           . :*  * *  

Mb0380c|M.bovis_AF2122/97           LDPVTGKLTLWTTSQAPHAHRTLYALVAGLPEHKIRVISPDIGGGFGNKV
Rv0373c|M.tuberculosis_H37Rv        LDPVTGKLTLWTTSQAPHAHRTLYALVAGLPEHKIRVISPDIGGGFGNKV
TH_1269|M.thermoresistible__bu      WQSASDELTIWASTQTPHELRAFAARLLGIPASRVRVIVKDTGGGFGQKV
MSMEG_5880|M.smegmatis_MC2_155      WQASAGELTIWASTQTPHELRAFAARLLGIPAQHVRVIMRDTGGGFGQKV
Mflv_1573|M.gilvum_PYR-GCK          WTSSTDELTIWASTQTPHELRAFAARLLGIPAQGVRVIMRDTGGAFGQKV
Mvan_5183|M.vanbaalenii_PYR-1       WTSTTNELTVWASTQTPHELRAFAARLLGIPAQGVRVIMRDTGGAFGQKV
MMAR_0623|M.marinum_M               WAPASEELTLWASTQTPHELRAFCARLLGIAAQRVRVIMRDTGGGFGQKV
MUL_0588|M.ulcerans_Agy99           WARASEELTLWASTQTPHELRAFCARLLGIAAQRVRVIMRDTGGGFGQKV
MAB_2925c|M.abscessus_ATCC_199      WQDERGRYVLRTSSQVPFLVRDELCHVFGLAREQVRVFAPRVGGGFGAKQ
                                          . .: :::*.*.  *   . : *:.   :**:    **.** * 

Mb0380c|M.bovis_AF2122/97           PIYPGYVCAIVASL---LLD---------KPVKWMEDRSENLTSTGFARD
Rv0373c|M.tuberculosis_H37Rv        PIYPGYVCAIVASL---LLD---------KPVKWMEDRSENLTSTGFARD
TH_1269|M.thermoresistible__bu      VPMREDMCIMIAAR---KVP---------APLKWIEDRRENLMAASQARH
MSMEG_5880|M.smegmatis_MC2_155      VPMREDMCIMLAAR---KTA---------GALKWIEDRRENLMSAGQSRH
Mflv_1573|M.gilvum_PYR-GCK          VPMREDMCILLAAR---RVP---------AALKWIEDRRENLMSAGQSRH
Mvan_5183|M.vanbaalenii_PYR-1       VPMREDMCILLAAR---KMPTATSNAQSGVAVKWIEDRRENLMSAGQSRH
MMAR_0623|M.marinum_M               VPMREDMCIMLAAR---KVP---------GALKWIEDRRENLMSAGQARH
MUL_0588|M.ulcerans_Agy99           VPMREDMCIMLAAR---KVP---------GALKWIEDRRENLMSAGQARH
MAB_2925c|M.abscessus_ATCC_199      EMLTEDLVLLAVRVTGA-------------PVVYEFTRSDQFTIAPCRHP
                                          :  : .                  .: :   * :::  :   : 

Mb0380c|M.bovis_AF2122/97           YIMVGEIAANRDGKILAIRSNVLADHGAFNAQAAPAKYPAGFFGVFTGSY
Rv0373c|M.tuberculosis_H37Rv        YIMVGEIAANRDGKILAIRSNVLADHGAFNAQAAPAKYPAGFFGVFTGSY
TH_1269|M.thermoresistible__bu      VDGDVRMAFDADGTILAADIDFIQDIGSY-PTPYPVLTTAAIGMFFPGPY
MSMEG_5880|M.smegmatis_MC2_155      VDGDVRMAFDPDGNILAADIDFVQDIGAY-PTPYPVLTTAAIGMFFPGPY
Mflv_1573|M.gilvum_PYR-GCK          VDGKVRMAFDDDGKILAADIDFIQDVGSY-PTPYPVLTTAAIGMFFPGPY
Mvan_5183|M.vanbaalenii_PYR-1       VDGKVRMAFDSDGKILAADIDFVQDVGSY-PTPYPVLTTAAIGMFFPGPY
MMAR_0623|M.marinum_M               VDGTARMAFDTDGNIQAADIDFIMDIGAY-PTPYPVLTTAAIGMFFPGPY
MUL_0588|M.ulcerans_Agy99           VDGTARMAFDSDGNIQAADVDFIMDIGAY-PTPYPVLTTAAIGMFFPGPY
MAB_2925c|M.abscessus_ATCC_199      MRVNVTAAADGDGVLTALAVDVLSDAGAYGNHSVGVMFHGCN--ESMAQY
                                           * : ** : *   :.: * *::   .  .   .       . *

Mb0380c|M.bovis_AF2122/97           DIEAAYCHMTAVYTNKAPGGVAYACSFRITEAVYFVERLVDCLAFELKMD
Rv0373c|M.tuberculosis_H37Rv        DIEAAYCHMTAVYTNKAPGGVAYACSFRITEAVYFVERLVDCLAFELKMD
TH_1269|M.thermoresistible__bu      RVPKASFNYKTVFSN-TAGLAAYRGPWQYETLSR--EILLDIAARKMGMD
MSMEG_5880|M.smegmatis_MC2_155      RVPKASFNYKTVFSN-TAGLHAYRGPWQYETLSR--EILLDIAARKIGID
Mflv_1573|M.gilvum_PYR-GCK          RVPKASFNYKTVFSN-TPGLHAYRGPWQYETLTR--EMLLDCAARKIGMD
Mvan_5183|M.vanbaalenii_PYR-1       RVPKASFNYKTVFSN-TPGLHAYRGPWQYETLTR--EMLLDSAARKIGMD
MMAR_0623|M.marinum_M               RIPKASFSYKTVFSN-TSGLAAYRGPWQYETLAR--EILLDIAARKMGID
MUL_0588|M.ulcerans_Agy99           RIPKASFSYKTVFSN-TSGLAAYRGPWQYETLAR--EILLDIAARKMGID
MAB_2925c|M.abscessus_ATCC_199      RCANKRVDAQAVYTN-NIPSGAFRG-YGLGQVLFGIESALDELARNLGID
                                              :*::*      *:   :         *  :*  * :: :*

Mb0380c|M.bovis_AF2122/97           PAELRLRNLLRPNQ---FPYQSKTGWVYDSGDYETTMRKAMNMIGYEALR
Rv0373c|M.tuberculosis_H37Rv        PAELRLRNLLRPNQ---FPYQSKTGWVYDSGDYETTMRKAMNMIGYEALR
TH_1269|M.thermoresistible__bu      PVDLRRKNLLRRDE---MPYFNPNGMPYDHVAPIETFEQAVKMADHEGFR
MSMEG_5880|M.smegmatis_MC2_155      PVELRRRNLLRRDE---MPYFNPNGMPYDHVAPAETFEQAVKILDHEGFR
Mflv_1573|M.gilvum_PYR-GCK          PVELRRINILRGDE---MPFFNPNGMPYDNCAPADTFEQAVKILDHEGFR
Mvan_5183|M.vanbaalenii_PYR-1       PVELRRINILRGDE---MPFFNPNGMPYDNCAPADTFEQAVKILDHEGFR
MMAR_0623|M.marinum_M               PIELRRRNLLRREE---MPYVNPNGMPYDHVAPIETLEQAVKILDYEGFR
MUL_0588|M.ulcerans_Agy99           PIELRRRNLLRREE---MPYVNPNGMPYDHVAPIETFEQAVKILDYEGFR
MAB_2925c|M.abscessus_ATCC_199      PFEFRRRNVIVPGDSFVSWEVEEDDLAFGSYGLDQCLDLAQDALARGAAD
                                    * ::*  *::   :       .  .  :.       :  * .     .  

Mb0380c|M.bovis_AF2122/97           AEQKQR-RARGELMGIGMSFFTEAVGAGPRKDMDILGLGMADGCELRVHP
Rv0373c|M.tuberculosis_H37Rv        AEQKQR-RARGELMGIGMSFFTEAVGAGPRKDMDILGLGMADGCELRVHP
TH_1269|M.thermoresistible__bu      KEQEEA-LAQGRYIGLGFSTYIEPTGAAT-------GHLAGEGATIRMES
MSMEG_5880|M.smegmatis_MC2_155      KQQAEA-LAQGRYIGLGFSAYIEPTGAAT-------GHLASEGATIRMES
Mflv_1573|M.gilvum_PYR-GCK          KEQAEA-LAEGRYIGLGFSAYIEPTGAAT-------GNLATEGATVRMES
Mvan_5183|M.vanbaalenii_PYR-1       KEQADA-LAEGRYIGLGFSAYIEPTGAAT-------GNLATEGATIRMES
MMAR_0623|M.marinum_M               REQREA-LAHGRYLGLGLSAYIEPTGAAT-------GHLATEGATIRMEP
MUL_0588|M.ulcerans_Agy99           REQREA-LAHGRYLGLGLSAYIEPTGAAT-------GHLATEGATIRMEP
MAB_2925c|M.abscessus_ATCC_199      PARNGSDLPAGWKVGEGMAIAMIATVPPR---------GHVADARAELDA
                                      :     . *  :* *::    .. .               ..  .:..

Mb0380c|M.bovis_AF2122/97           TGKAVLRLSVQTQGQGHETTFAQIVAEELGIAPDDIEVVHGDTDQTPFGL
Rv0373c|M.tuberculosis_H37Rv        TGKAVLRLSVQTQGQGHETTFAQIVAEELGIAPDDIEVVHGDTDQTPFGL
TH_1269|M.thermoresistible__bu      TGKINVYVNGGSSGNSIETTVVQLTADALGADIDDVATIQGDTAVTPYGA
MSMEG_5880|M.smegmatis_MC2_155      TGKINVYVNGGSTGNSLETTVIQLTADALGADIDDVATIQGDTAVTPYGA
Mflv_1573|M.gilvum_PYR-GCK          TGKINVYVNGGSAGNSIETTVVQLTADALGANIDDVATIQGDTAVTPYGA
Mvan_5183|M.vanbaalenii_PYR-1       TGKINVYVNGGSAGNSIETTVVQLTADALGANIEDVATIQGDTAVTPYGA
MMAR_0623|M.marinum_M               TGKVNVYVNGGSSGNSLETTVIQLTADALGADIDDVATIQGDTAITPYGA
MUL_0588|M.ulcerans_Agy99           TGKVNVYVNGGSSGNSLETTVIQLTADALGADIDDVATIQGDTAITPYGA
MAB_2925c|M.abscessus_ATCC_199      RGRYRISVGSAEFGNGTTTVHAQLAAGVLGCAPDQVYIHQADTDAVSHDT
                                     *:  : :.    *:.  *.  *:.*  **   :::   :.**  .... 

Mb0380c|M.bovis_AF2122/97           GTYGSRSTPVSGGAAALVARKVRDKAKIIASGMLEVSVADLQWEKGKFHV
Rv0373c|M.tuberculosis_H37Rv        GTYGSRSTPVSGGAAALVARKVRDKAKIIASGMLEVSVADLQWEKGKFHV
TH_1269|M.thermoresistible__bu      GTQGSRSAPMTAGAVHEAGSILRKQIVTIAAHMLDTDESQIELAGSRAVV
MSMEG_5880|M.smegmatis_MC2_155      GTQGSRSAPMTAGAVNEAGTMLRNQIVAMAAAWLGVEEPEIELGGSKATV
Mflv_1573|M.gilvum_PYR-GCK          GTQGSRSAPMTAGAVNEAGAILRTQIIAIAAQILGVEAAEIELANSRASV
Mvan_5183|M.vanbaalenii_PYR-1       GTQGSRSAPMTAGAVNEAGAILRRQIIAIGAQILGVEESEIELANSRAGV
MMAR_0623|M.marinum_M               GTQGSRSGPMTAGAVNEAGKILREKIVALAAHHLEVAESEVELVHSKAAV
MUL_0588|M.ulcerans_Agy99           GTQCSRSGPMTAGAVNEAGKTLREKIVALAAHHLEVAESEVELAHSKAAV
MAB_2925c|M.abscessus_ATCC_199      GAFGSAGTTVAGLAVYRAAELLRDQIIRFAATKLAVPQSRCVLEPDGVRA
                                    *:  * . .::. *.  ..  :* :   :.:  * .  .      .   .

Mb0380c|M.bovis_AF2122/97           KGDPSAAVTIADIAMRAHG-AGDLPEGIEGGLDAEVCYNP---SNLTYPY
Rv0373c|M.tuberculosis_H37Rv        KGDPSAAVTIADIAMRAHG-AGDLPEGIEGGLDAEVCYNP---SNLTYPY
TH_1269|M.thermoresistible__bu      RDDPDKSVSFADLAYRAYYEPQMLPPGTSATLEATARFTS--QAPIHWAN
MSMEG_5880|M.smegmatis_MC2_155      RSDPDKSVTFGQLAYRAYYEPQQLPPGLSASLEATARYTAPPTAPIHWAN
Mflv_1573|M.gilvum_PYR-GCK          RSDPEKSVSFADIAYRSYYDPGQLG-GVSPTLEATARFNS--QAMIHWAN
Mvan_5183|M.vanbaalenii_PYR-1       RNDPERSVSFADIAYRSYYDPAQLG-GVSPTLEATARFNS--QAMIHWAN
MMAR_0623|M.marinum_M               RGDPARQVTFGELAYTAYYSPQQLPSALSTELEGTARFKS--PNPIHWAN
MUL_0588|M.ulcerans_Agy99           RGDPARQVTFGELAYTAYYSPQQLPSAMSPELEGTARFKS--PNPIHWAN
MAB_2925c|M.abscessus_ATCC_199      GADLLG--------------LTEIAASAPEPLSAVGHHEG---TPRSVAF
                                      *                    :  .    *..   .          . 

Mb0380c|M.bovis_AF2122/97           GAYFCVVDIDPGTAVVKVRRFLAVDDCGTRINPMIIEGQVHGGIVDGIGM
Rv0373c|M.tuberculosis_H37Rv        GAYFCVVDIDPGTAVVKVRRFLAVDDCGTRINPMIIEGQVHGGIVDGIGM
TH_1269|M.thermoresistible__bu      ATHACTCEVDTVTGHVTLTNYVVSEDVGPMINPNVVEGQIAGGTVQGIGG
MSMEG_5880|M.smegmatis_MC2_155      ATHACTCEVDIETGQVTLTRYIVSEDVGPMINPNVVEGQIAGGTVQGIGG
Mflv_1573|M.gilvum_PYR-GCK          ATHVCTCEVDVETGHVTLTRYIVSEDVGPMINPNIVEGQVAGGTVQGIGG
Mvan_5183|M.vanbaalenii_PYR-1       ATHVCTCEVDVETGQVTLTRYIVSEDVGPMINPNIVEGQVAGGTVQGIGG
MMAR_0623|M.marinum_M               ATHACTCEVDTQTGKVTLLRYVVSEDVGPMINPAVVEGQIAGGTVQGIGG
MUL_0588|M.ulcerans_Agy99           ATHACTCEVDTQTGKVTLLRYVVSEDVGPMINPAVVEGQIAGGTVQGIGG
MAB_2925c|M.abscessus_ATCC_199      NVQAFRVAVRPQTGTVRILQSVQTADAGVVVNPQQCRGQVEGGVAQAIGS
                                     .      :   *. * : . :   * *  :**   .**: ** .:.** 

Mb0380c|M.bovis_AF2122/97           ALMEMIAFDEDGNCLGGSLMDYLIPTALEVPHLETGHTVTPSPHHPIGAK
Rv0373c|M.tuberculosis_H37Rv        ALMEMIAFDEDGNCLGGSLMDYLIPTALEVPHLETGHTVTPSPHHPIGAK
TH_1269|M.thermoresistible__bu      ALLEHQAYDADGNPLSSTFVDYLLPTATEVPLIEYGHIEVPGPG-VGGYK
MSMEG_5880|M.smegmatis_MC2_155      ALLEQLAYDDAGNPLSSTFVDYLLPTATEVPAIEYGHVEIPGPG-VGGYK
Mflv_1573|M.gilvum_PYR-GCK          ALLEKLAYDDDGNPVASTFVDYLLPTATEVPPIEFGHVEIPGPG-VGGYK
Mvan_5183|M.vanbaalenii_PYR-1       ALLEKLAYDDAGNPVASTFVDYLLPTATEVPPIEFGHVEIPGPG-VGGYK
MMAR_0623|M.marinum_M               ALMENLAYDDDGNPLATTFVDYLLPTATEVPPIEYGHVEIPGPG-PGGYK
MUL_0588|M.ulcerans_Agy99           ALMENLAYDDDGNPLATTFVDYLLPTATEVPPIEYGHVEIPGPG-PGGYK
MAB_2925c|M.abscessus_ATCC_199      ALYEEILVHD-GFVSTTALRNYHIPRLVDVPDTEVYFADTYDTFGPLGAK
                                    ** *    .  *     :: :* :*   :**  *  .    ..    * *

Mb0380c|M.bovis_AF2122/97           GIGESATVGSPPAVVNAVVDALAPFGVRHADMPLTPSRVWEAMQGRATPP
Rv0373c|M.tuberculosis_H37Rv        GIGESATVGSPPAVVNAVVDALAPFGVRHADMPLTPSRVWEAMQGRATPP
TH_1269|M.thermoresistible__bu      GAGEGGAIGSTPAVINAINDALAALGVTVTRLPATPATIVELIEQATSKD
MSMEG_5880|M.smegmatis_MC2_155      GAGEGGAIGSTPAVINAVNDALAPLGVTITTLPASPAAISAAIEAAIETR
Mflv_1573|M.gilvum_PYR-GCK          GAGEGGAIGSPPAVINAVNDALAPLGVTLTQLPATPATIVELIDAASRKD
Mvan_5183|M.vanbaalenii_PYR-1       GAGEGGAIGSPPAVINAINDALAPLGVTLTQLPATPATIVELIERAG-KD
MMAR_0623|M.marinum_M               GAGEGGAIGSAPAVINAINDALAPLGVTVTRLPASPASVASLLAGASR--
MUL_0588|M.ulcerans_Agy99           GAGEGGAIGSAPAVINAINDALAPLGVTVTRLPASPASVASLLAGASR--
MAB_2925c|M.abscessus_ATCC_199      SMSESPYNPVAPALANAIRDAVG---VRVYRLPMNAARVWRVINDSGGGE
                                    . .*.     .**: **: **:.   *    :* ..: :   :       

Mb0380c|M.bovis_AF2122/97           I---
Rv0373c|M.tuberculosis_H37Rv        I---
TH_1269|M.thermoresistible__bu      QKWN
MSMEG_5880|M.smegmatis_MC2_155      GKDH
Mflv_1573|M.gilvum_PYR-GCK          H---
Mvan_5183|M.vanbaalenii_PYR-1       H---
MMAR_0623|M.marinum_M               ----
MUL_0588|M.ulcerans_Agy99           ----
MAB_2925c|M.abscessus_ATCC_199      SS--