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M. tuberculosis H37Rv Rv0373c (-)

annotation: PROBABLE CARBON MONOXYDE DEHYDROGENASE (LARGE CHAIN)
coordinates: 449404 - 451803
length: 799

TTIESRPPSPEDLADNAQQPCGHGRMMRKEDPRFIRGRGTYVDDVALPGMLHLAILRSPYAHARIVRIDV
TAAQAHPKVKAVVTGADLAAKGLAWMPTLANDVQAVLATDKTRFQGQEVAFVVAEDRYSARDACELVDVD
YEPRDPVVDARTALDPSAPVIRTDLEGKSDNHIFDWETGDAAATEAVFAKADVVVQQEIVYPRVHPAPME
TCGAVADLDPVTGKLTLWTTSQAPHAHRTLYALVAGLPEHKIRVISPDIGGGFGNKVPIYPGYVCAIVAS
LLLDKPVKWMEDRSENLTSTGFARDYIMVGEIAANRDGKILAIRSNVLADHGAFNAQAAPAKYPAGFFGV
FTGSYDIEAAYCHMTAVYTNKAPGGVAYACSFRITEAVYFVERLVDCLAFELKMDPAELRLRNLLRPNQF
PYQSKTGWVYDSGDYETTMRKAMNMIGYEALRAEQKQRRARGELMGIGMSFFTEAVGAGPRKDMDILGLG
MADGCELRVHPTGKAVLRLSVQTQGQGHETTFAQIVAEELGIAPDDIEVVHGDTDQTPFGLGTYGSRSTP
VSGGAAALVARKVRDKAKIIASGMLEVSVADLQWEKGKFHVKGDPSAAVTIADIAMRAHGAGDLPEGIEG
GLDAEVCYNPSNLTYPYGAYFCVVDIDPGTAVVKVRRFLAVDDCGTRINPMIIEGQVHGGIVDGIGMALM
EMIAFDEDGNCLGGSLMDYLIPTALEVPHLETGHTVTPSPHHPIGAKGIGESATVGSPPAVVNAVVDALA
PFGVRHADMPLTPSRVWEAMQGRATPPI*
Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. tuberculosis H37RvRv0373c--100% (799)PROBABLE CARBON MONOXYDE DEHYDROGENASE (LARGE CHAIN)

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97Mb0380c-0.099.87% (799) carbon monoxyde dehydrogenase large subunit
M. gilvum PYR-GCKMflv_1573-1e-13037.34% (774) carbon-monoxide dehydrogenase (acceptor)
M. leprae Br4923-----
M. abscessus ATCC 19977MAB_2925c-4e-5728.84% (794) xanthine dehydrogenase family protein
M. marinum MMMAR_0657coxL0.092.24% (799) carbon monoxyde dehydrogenase (large chain), CoxL
M. avium 104-----
M. smegmatis MC2 155MSMEG_0746-0.089.99% (799) carbon-monoxide dehydrogenase, large subunit
M. thermoresistible (build 8)TH_0176-0.089.62% (800) PROBABLE CARBON MONOXYDE DEHYDROGENASE (LARGE CHAIN)
M. ulcerans Agy99MUL_0115coxL0.091.11% (799) carbon monoxyde dehydrogenase (large chain), CoxL
M. vanbaalenii PYR-1Mvan_5183-1e-12435.91% (788) carbon-monoxide dehydrogenase (acceptor)

CLUSTAL 2.0.9 multiple sequence alignment


Mflv_1573|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_5183|M.vanbaalenii_PYR-1       --------------------------------------------------
Rv0373c|M.tuberculosis_H37Rv        --------------------------------------------------
Mb0380c|M.bovis_AF2122/97           --------------------------------------------------
MMAR_0657|M.marinum_M               --------------------------------------------------
MUL_0115|M.ulcerans_Agy99           --------------------------------------------------
MSMEG_0746|M.smegmatis_MC2_155      --------------------------------------------------
TH_0176|M.thermoresistible__bu      --------------------------------------------------
MAB_2925c|M.abscessus_ATCC_199      MKVNGKLIDASPRPGQCLRTFLREHGHVEVKKGCDAGDCGACTVLVDGAS
                                                                                      

Mflv_1573|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_5183|M.vanbaalenii_PYR-1       --------------------------------------------------
Rv0373c|M.tuberculosis_H37Rv        --------------------------------------------------
Mb0380c|M.bovis_AF2122/97           --------------------------------------------------
MMAR_0657|M.marinum_M               --------------------------------------------------
MUL_0115|M.ulcerans_Agy99           --------------------------------------------------
MSMEG_0746|M.smegmatis_MC2_155      --------------------------------------------------
TH_0176|M.thermoresistible__bu      --------------------------------------------------
MAB_2925c|M.abscessus_ATCC_199      QHSCIVPAHRVTDAEIHTVRSLAGEHDLHPMQRGFIDHAGFQCGFCTAGM
                                                                                      

Mflv_1573|M.gilvum_PYR-GCK          ---MTDAD-------VQAVDAVSPRYAGQR---------------VPRVE
Mvan_5183|M.vanbaalenii_PYR-1       ---MTDT----------ATNAVTARYAGQR---------------VPRVE
Rv0373c|M.tuberculosis_H37Rv        ---MTTIESRPPS-PEDLADNAQQPCGHGR---------------MMRKE
Mb0380c|M.bovis_AF2122/97           ---MTTIESRPPS-PEDLADNAQQPCGHGR---------------MMRKE
MMAR_0657|M.marinum_M               ---MTTIESRP----EDLADNDQKPCGHGR---------------MLRKE
MUL_0115|M.ulcerans_Agy99           ---MTTIESRP----EDLADNDQKPCGHGR---------------MLRKE
MSMEG_0746|M.smegmatis_MC2_155      ---MTTLENPVER-PEDTAVNDAKPCGHGR---------------MLRKE
TH_0176|M.thermoresistible__bu      ---MTTLESNPAARPDDFENNDQKPCGHGR---------------MLRKE
MAB_2925c|M.abscessus_ATCC_199      VLTAATLTGDQTEDLGNALKGNLCRCTGYRPIRDAVCGVVPPRGSVSAPA
                                        :                        *               :    

Mflv_1573|M.gilvum_PYR-GCK          DSRLLTGQGRFVDDISRPGMLHACFVRSPFARATIRGIDTSAALALPGVH
Mvan_5183|M.vanbaalenii_PYR-1       DSRLLTGHGRFVDDISRPGMLHACFVRSPFAHATINGVDASAALALPGVH
Rv0373c|M.tuberculosis_H37Rv        DPRFIRGRGTYVDDVALPGMLHLAILRSPYAHARIVRIDVTAAQAHPKVK
Mb0380c|M.bovis_AF2122/97           DPRFIRGRGTYVDDVALPGMLHLAILRSPYAHARIVRIDVTAAQAHPKVK
MMAR_0657|M.marinum_M               DPRFIRGRGNYVDDVALPGMLHLAILRSPYAHARIVSIDVTAALAHPKVK
MUL_0115|M.ulcerans_Agy99           DPRFIRGRGNYVDDVALPGMLHLAIFRSPYAHARIVSIDVTAALAHPKVK
MSMEG_0746|M.smegmatis_MC2_155      DPRFIRGRGNYVDDVKLPGMLHLAILRSPYAHATINSIDVTAAQAHPKVK
TH_0176|M.thermoresistible__bu      DPRFIRGRGRYVDDVQLPGMLHLAILRSPYAHARIAGIDTSAAQAHPKVK
MAB_2925c|M.abscessus_ATCC_199      AARVVTGTEPYTMDELPAGVGHVAVLGSPHPSARITRIDTDRARLLPGVR
                                     .*.: *   :. *   .*: * ... **.. * *  :*.  *   * *:

Mflv_1573|M.gilvum_PYR-GCK          AVFTASDLNPDVREAWHAVAGKDVPDTPRPPLAEGEVKFVGDPVALVVAD
Mvan_5183|M.vanbaalenii_PYR-1       AVFTAADLNPDVKEAWHAVAGKDVPDTPRPPLAEGEVKFVGDPVALVVAD
Rv0373c|M.tuberculosis_H37Rv        AVVTGADLAAKG-LAWMPTLANDVQAV----LATDKTRFQGQEVAFVVAE
Mb0380c|M.bovis_AF2122/97           AVVTGADLAAKG-LAWMPTLANDVQAV----LATDKTRFQGQEVASVVAE
MMAR_0657|M.marinum_M               AVVTGADLAEKG-LAWMPTLSNDVQAV----LATDKVRFQGQEVAFVVAE
MUL_0115|M.ulcerans_Agy99           AVVTGADLAEKG-LAWMPTLSNDVQAV----LATDKVHFQGQEVVFVVAE
MSMEG_0746|M.smegmatis_MC2_155      AVVTGADLAAKG-LAWMPTLSNDVQAV----LATDKVRFQGQEVAFVVAE
TH_0176|M.thermoresistible__bu      AVVTGADLAEKG-LAWMPTLSNDVQAV----LATDKVRFQGQEVAFVVAE
MAB_2925c|M.abscessus_ATCC_199      AVLCYRDDPGVPFSTARHHERTDDPDD--TLVFDRVLRFAGQRVAAVVAD
                                    **.   *       :      .*        :     :* *: *. ***:

Mflv_1573|M.gilvum_PYR-GCK          SRYLAEDAVDLVEVDYEPLPAVADFRKAVGGASAGVP--------VVHEA
Mvan_5183|M.vanbaalenii_PYR-1       SRYLAEDAVDLVEVDYDPLPAVADFRKAVGGAEAGVP--------VVHAA
Rv0373c|M.tuberculosis_H37Rv        DRYSARDACELVDVDYEPRDPVVDARTALDPSAPVIR--------TDLEG
Mb0380c|M.bovis_AF2122/97           DRYSARDACELVDVDYEPRDPVVDARTALDPSAPVIR--------TDLEG
MMAR_0657|M.marinum_M               DRYSARDALELIDVEYDPLDPVVDVRKALDPSAPVIR--------TDLDG
MUL_0115|M.ulcerans_Agy99           DRYSARDALELIDVEYDPLDPVVDVRKALHPSAPVIR--------TDLDG
MSMEG_0746|M.smegmatis_MC2_155      DRYSARDALELIDVDYEPLDPVIDARHALDPGAPVIR--------TDLDG
TH_0176|M.thermoresistible__bu      DHYSARDALELIDVDYDPLDPVVDVRRALEPDAPVIR--------TDLDG
MAB_2925c|M.abscessus_ATCC_199      TPAIAHRALEHIDVEYEVLPAVFDPEMAQLPGAHLVHGDKGLGARIADPA
                                        *. * : ::*:*:   .* * . *       :             .

Mflv_1573|M.gilvum_PYR-GCK          YPDN--VAGGMGGMPPDEELFATAPHVVEQHIYQQMYVPVPMETRGMVVE
Mvan_5183|M.vanbaalenii_PYR-1       YPDN--VAGGMGGMPPDEEIFATAAHVVEEHIYQQMYVPVPMETRGMVVE
Rv0373c|M.tuberculosis_H37Rv        KSDNHIFDWETGDAAATEAVFAKADVVVQQEIVYPRVHPAPMETCGAVAD
Mb0380c|M.bovis_AF2122/97           KSDNHIFDWETGDAAATEAVFAKADVVVQQEIVYPRVHPAPMETCGAVAD
MMAR_0657|M.marinum_M               KQDNHIFDWETGDAAATDAVFAKADVVIKQEMVYPRVHPAPMETCGAVAD
MUL_0115|M.ulcerans_Agy99           KQDNHIFDWETGDAAATDAVFAKADVVIKQEMVYPRVHPAPMETCGAVAD
MSMEG_0746|M.smegmatis_MC2_155      KTDNHCFDWETGDAAATDAVFAKADVVVKQEMVYPRVHPAPMETCGAVAD
TH_0176|M.thermoresistible__bu      KTDNHCFDWETGDPAATEAAFAKADVVVEQEIVYPRVHPAPMETCGAVAD
MAB_2925c|M.abscessus_ATCC_199      RNLVAEVHGEVGDVAAALARARESGAVVTGSWQTARVQHVHLETHGSVG-
                                          .    *. ..       :  *:           . :** * *  

Mflv_1573|M.gilvum_PYR-GCK          WTSSTDELTIWASTQTPHELRAFAARLLGIPAQGVRVIMRDTGGAFGQKV
Mvan_5183|M.vanbaalenii_PYR-1       WTSTTNELTVWASTQTPHELRAFAARLLGIPAQGVRVIMRDTGGAFGQKV
Rv0373c|M.tuberculosis_H37Rv        LDPVTGKLTLWTTSQAPHAHRTLYALVAGLPEHKIRVISPDIGGGFGNKV
Mb0380c|M.bovis_AF2122/97           LDPVTGKLTLWTTSQAPHAHRTLYALVAGLPEHKIRVISPDIGGGFGNKV
MMAR_0657|M.marinum_M               LDPVTGKLTLWTTSQAPHAHRTLYALVAGLPEHKIRVISPDIGGGFGNKV
MUL_0115|M.ulcerans_Agy99           LDPVTGKLTLWTTSQAPHAHRTLYALVAGLPEHKIRVISPDIGGGFGNKV
MSMEG_0746|M.smegmatis_MC2_155      LDPVTRKLTLWSTTQAPHAHRTLYALVAGLPEHKIRVISPDIGGGFGNKV
TH_0176|M.thermoresistible__bu      LDPVTGKLTLWSTSQAPHAHRTLYALVAGLPEHKIRVIAPDIGGGFGNKV
MAB_2925c|M.abscessus_ATCC_199      WQDERGRYVLRTSSQVPFLVRDELCHVFGLAREQVRVFAPRVGGGFGAKQ
                                          . .: :::*.*.  *   . : *:. . :**:    **.** * 

Mflv_1573|M.gilvum_PYR-GCK          VPMREDMCILLAARRVP---------AALKWIEDRRENLMSAGQSRHVDG
Mvan_5183|M.vanbaalenii_PYR-1       VPMREDMCILLAARKMPTATSNAQSGVAVKWIEDRRENLMSAGQSRHVDG
Rv0373c|M.tuberculosis_H37Rv        PIYPGYVCAIVASLLLD---------KPVKWMEDRSENLTSTGFARDYIM
Mb0380c|M.bovis_AF2122/97           PIYPGYVCAIVASLLLD---------KPVKWMEDRSENLTSTGFARDYIM
MMAR_0657|M.marinum_M               PIYPGYVCAIVGSLVLG---------KPVKWMEDRSENLTSTSFARDYIM
MUL_0115|M.ulcerans_Agy99           PIYPGYVCAIVGSSVLG---------KPVKWMEDRSENLTSTSFARDYIM
MSMEG_0746|M.smegmatis_MC2_155      PIYPGYVCAIVGSLLLG---------KPVKWMEDRSENLTSTGFARDYIM
TH_0176|M.thermoresistible__bu      PIYPGYVCAIVGSLLLG---------KPVKWVEDRSENLTSTGFARDYIM
MAB_2925c|M.abscessus_ATCC_199      EMLTEDLVLLAVRVTGA----------PVVYEFTRSDQFTIAPCRHPMRV
                                          :  :                 .: :   * :::  :   :    

Mflv_1573|M.gilvum_PYR-GCK          KVRMAFDDDGKILAADIDFIQDVGSYP-TPYPVLTTAAIGMFFPGPYRVP
Mvan_5183|M.vanbaalenii_PYR-1       KVRMAFDSDGKILAADIDFVQDVGSYP-TPYPVLTTAAIGMFFPGPYRVP
Rv0373c|M.tuberculosis_H37Rv        VGEIAANRDGKILAIRSNVLADHGAFNAQAAPAKYPAGFFGVFTGSYDIE
Mb0380c|M.bovis_AF2122/97           VGEIAANRDGKILAIRSNVLADHGAFNAQAAPAKYPAGFFGVFTGSYDIE
MMAR_0657|M.marinum_M               VGEIAATNEGKILALRSHVLADHGAFNGQAAPTKYPAGFYGVFTGSYDLE
MUL_0115|M.ulcerans_Agy99           VGEIAATNEGKILALRSHVLADHGAFNGQAAPTKYPAGFYGVFTGSYDLE
MSMEG_0746|M.smegmatis_MC2_155      VGEIAATRDGKILAIRSNVLADHGAFNGTAAPVKYPAGFFGVFTGSYDIE
TH_0176|M.thermoresistible__bu      VGEIAATRDGRILAIRSHVLADHGAFNGTAAPVKYPAGFFGVFTGSYDLE
MAB_2925c|M.abscessus_ATCC_199      NVTAAADGDGVLTALAVDVLSDAGAYGNHSVGVMFHG--CNESMAQYRCA
                                        *   :* : *   ..: * *::   .  .   .       . *   

Mflv_1573|M.gilvum_PYR-GCK          KASFNYKTVFSN-TPGLHAYRGPWQYETLTR--EMLLDCAARKIGMDPVE
Mvan_5183|M.vanbaalenii_PYR-1       KASFNYKTVFSN-TPGLHAYRGPWQYETLTR--EMLLDSAARKIGMDPVE
Rv0373c|M.tuberculosis_H37Rv        AAYCHMTAVYTNKAPGGVAYACSFRITEAVYFVERLVDCLAFELKMDPAE
Mb0380c|M.bovis_AF2122/97           AAYCHMTAVYTNKAPGGVAYACSFRITEAVYFVERLVDCLAFELKMDPAE
MMAR_0657|M.marinum_M               AAYCHMTAVYTNKAPGGVAYACSFRITEAVYFVERLVDCLAFELKMDPAE
MUL_0115|M.ulcerans_Agy99           AAYCHMTAVYTNKAPGGVAYACSFRITEAVYFVERLVDCLAFELKMGPAE
MSMEG_0746|M.smegmatis_MC2_155      AAYCHMTAVYTNKAPGGVAYACSFRITEAVYFVERLVDCLAYELKMDPAQ
TH_0176|M.thermoresistible__bu      AAYCHMTAVYTNKAPGGVAYACSFRITEAVYLVERLVDCLAHELEMDPAE
MAB_2925c|M.abscessus_ATCC_199      NKRVDAQAVYTNNIPSGAFRG--YGLGQVLFGIESALDELARNLGIDPFE
                                        .  :*::*  *.       :         *  :*  * :: :.* :

Mflv_1573|M.gilvum_PYR-GCK          LRRINILRGDE---MPFFNPNGMPYDNCAPADTFEQAVKILDHEGFR-KE
Mvan_5183|M.vanbaalenii_PYR-1       LRRINILRGDE---MPFFNPNGMPYDNCAPADTFEQAVKILDHEGFR-KE
Rv0373c|M.tuberculosis_H37Rv        LRLRNLLRPNQ---FPYQSKTGWVYDSGDYETTMRKAMNMIGYEALR-AE
Mb0380c|M.bovis_AF2122/97           LRLRNLLRPNQ---FPYQSKTGWVYDSGDYETTMRKAMNMIGYEALR-AE
MMAR_0657|M.marinum_M               VRLRNLLKPEQ---FPYTTKTGWVYDSGDYESTMRQAMDMIGYDALR-AE
MUL_0115|M.ulcerans_Agy99           LRLRNLLKPEQ---FPYTTKTGWVYDSGDYESTMRQAMDMIGGDALR-AE
MSMEG_0746|M.smegmatis_MC2_155      LRLQNLLKAEQ---FPYTSKTGWVYDSGDYEKTMRLAMEMVDYEGLR-AE
TH_0176|M.thermoresistible__bu      LRLRNLLKPDQ---FPYTSKTGWVYDSGDYETTMRKAMAMVGYDELR-AE
MAB_2925c|M.abscessus_ATCC_199      FRRRNVIVPGDSFVSWEVEEDDLAFGSYGLDQCLDLAQDALARGAADPAR
                                    .*  *::   :          .  :..      :  *   :        .

Mflv_1573|M.gilvum_PYR-GCK          QAEALAEGRYIGLGFSAYIEPTGAAT-------GNLATEGATVRMESTGK
Mvan_5183|M.vanbaalenii_PYR-1       QADALAEGRYIGLGFSAYIEPTGAAT-------GNLATEGATIRMESTGK
Rv0373c|M.tuberculosis_H37Rv        QKQRRARGELMGIGMSFFTEAVGAGPRKDMDILGLGMADGCELRVHPTGK
Mb0380c|M.bovis_AF2122/97           QKQRRARGELMGIGMSFFTEAVGAGPRKDMDILGLGMADGCELRVHPTGK
MMAR_0657|M.marinum_M               QKEKRDRGELMGIGISFFTEAVGAGPRKDMDILGLGMADGCELRVHPTGK
MUL_0115|M.ulcerans_Agy99           QKEKRDRGELMGIGISFFTEAVGAGPRKDMDILGLGMADGCELRVHPTGK
MSMEG_0746|M.smegmatis_MC2_155      QAEKRKRGELMGIGMSFFTEAVGAGPRKDMDILGLGMADGCELRVHPTGK
TH_0176|M.thermoresistible__bu      QAERRRRGELMGIGMSFFTEAVGAGPRKDMDILGLGMADGCELRVHPTGK
MAB_2925c|M.abscessus_ATCC_199      NGSDLPAGWKVGEGMAIAMIATVPPR---------GHVADARAELDARGR
                                    : .    *  :* *::    .. .             . ..  .:.. *:

Mflv_1573|M.gilvum_PYR-GCK          INVYVNGGSAGNSIETTVVQLTADALGANIDDVATIQGDTAVTPYGAGTQ
Mvan_5183|M.vanbaalenii_PYR-1       INVYVNGGSAGNSIETTVVQLTADALGANIEDVATIQGDTAVTPYGAGTQ
Rv0373c|M.tuberculosis_H37Rv        AVLRLSVQTQGQGHETTFAQIVAEELGIAPDDIEVVHGDTDQTPFGLGTY
Mb0380c|M.bovis_AF2122/97           AVLRLSVQTQGQGHETTFAQIVAEELGIAPDDIEVVHGDTDQTPFGLGTY
MMAR_0657|M.marinum_M               AVVRLSVQTQGQGHETTFAQIVAEELGIPPDDIDVVHGDTDQTPFGLGTY
MUL_0115|M.ulcerans_Agy99           AVVRLSVQTQGQGHETTFAQIVAEELGIPTDDIDVAHGDTDQTPFGLGTY
MSMEG_0746|M.smegmatis_MC2_155      AVVRLSVQSQGQGHETTFAQIVAEELGIPPEDIDVVHGDTDQTPFGLGTY
TH_0176|M.thermoresistible__bu      AVVRLSVQTQGQGHETTFAQIVAEELGIPPDDIEVVHGDTDQTPFGLGTY
MAB_2925c|M.abscessus_ATCC_199      YRISVGSAEFGNGTTTVHAQLAAGVLGCAPDQVYIHQADTDAVSHDTGAF
                                      : :.    *:.  *. .*:.*  **   :::   :.**  .... *: 

Mflv_1573|M.gilvum_PYR-GCK          GSRSAPMTAGAVNEAGAILRTQIIAIAAQILGVEAAEIELANSRASVRSD
Mvan_5183|M.vanbaalenii_PYR-1       GSRSAPMTAGAVNEAGAILRRQIIAIGAQILGVEESEIELANSRAGVRND
Rv0373c|M.tuberculosis_H37Rv        GSRSTPVSGGAAALVARKVRDKAKIIASGMLEVSVADLQWEKGKFHVKGD
Mb0380c|M.bovis_AF2122/97           GSRSTPVSGGAAALVARKVRDKAKIIASGMLEVSVADLQWEKGKFHVKGD
MMAR_0657|M.marinum_M               GSRSTPVSGAAAALVARKVRDKAKIIASGMLEVSVADLEWEKGSFHVKGD
MUL_0115|M.ulcerans_Agy99           GSRSTPVSGAAAALVARKVRDKAKIIASGMLEVSVADLEWEKGSFHVKGD
MSMEG_0746|M.smegmatis_MC2_155      GSRSTPVSGAAAALVARKVRDKAKIIAAGMLEASIADLEWDKGSFHIKGD
TH_0176|M.thermoresistible__bu      GSRSTPVSGAAAALVARKVRDKAKIIASGMLEASIADLEWEKGSFRVKGD
MAB_2925c|M.abscessus_ATCC_199      GSAGTTVAGLAVYRAAELLRDQIIRFAATKLAVPQSRCVLEPDGVRAGAD
                                    ** .:.::. *.  ..  :* :   :.:  * .  :      .      *

Mflv_1573|M.gilvum_PYR-GCK          PEKSVSFADIAYRSYYDPGQLGGVSPTLEATARFNSQAMIHWANATHVCT
Mvan_5183|M.vanbaalenii_PYR-1       PERSVSFADIAYRSYYDPAQLGGVSPTLEATARFNSQAMIHWANATHVCT
Rv0373c|M.tuberculosis_H37Rv        PSAAVTIADIAMRAHGAGDLPEGIEGGLDAEVCYN-PSNLTYPYGAYFCV
Mb0380c|M.bovis_AF2122/97           PSAAVTIADIAMRAHGAGDLPEGIEGGLDAEVCYN-PSNLTYPYGAYFCV
MMAR_0657|M.marinum_M               PSASVTIADIAMRAHGAGDLPEGIEGGLDAEVCYN-PSNLTYPYGAYFCV
MUL_0115|M.ulcerans_Agy99           PSASVTIADIAMRAHGAGDLPEGIEGGLDAEVCYN-PSNLTYPYGAYFCV
MSMEG_0746|M.smegmatis_MC2_155      PSASVTIADIAMRAHGAGDLPEGLEGGLDAQICYN-PSNLTYPYGAYFCV
TH_0176|M.thermoresistible__bu      PSASVTIQDIAMRAHGAGDLPDGIEGGLDAQICYN-PSNLTYPYGAYFCV
MAB_2925c|M.abscessus_ATCC_199      LLGLTEIAASAPEPLSAVGHHEGTPRSVAFN--------------VQAFR
                                        . :   * ..        *    :                 .    

Mflv_1573|M.gilvum_PYR-GCK          CEVDVETGHVTLTRYIVSEDVGPMINPNIVEGQVAGGTVQGIGGALLEKL
Mvan_5183|M.vanbaalenii_PYR-1       CEVDVETGQVTLTRYIVSEDVGPMINPNIVEGQVAGGTVQGIGGALLEKL
Rv0373c|M.tuberculosis_H37Rv        VDIDPGTAVVKVRRFLAVDDCGTRINPMIIEGQVHGGIVDGIGMALMEMI
Mb0380c|M.bovis_AF2122/97           VDIDPGTAVVKVRRFLAVDDCGTRINPMIIEGQVHGGIVDGIGMALMEMI
MMAR_0657|M.marinum_M               VDVDPGTGVVKVRRFLAVDDCGTRINPMIIEGQVHGGIVDGIGMALMEMI
MUL_0115|M.ulcerans_Agy99           VDVDPGTGVVKVRRFLAVDDAGTRINPMIIEGQVHGGIVDGIGMALMEMI
MSMEG_0746|M.smegmatis_MC2_155      VDIDPGTAVVKVRRFVAVDDCGTRINPMIIEGQIHGGLVDGIGMALMEMI
TH_0176|M.thermoresistible__bu      VDVDPGTAVVKVRRFLAVDDCGTRINPMIIEGQVHGGIVDGIGMALMQMI
MAB_2925c|M.abscessus_ATCC_199      VAVRPQTGTVRILQSVQTADAGVVVNPQQCRGQVEGGVAQAIGSALYEEI
                                      :   *. * : : :   * *  :**   .**: ** .:.** ** : :

Mflv_1573|M.gilvum_PYR-GCK          AYDDDGNPVASTFVDYLLPTATEVPPIEFGHVEIPGPGVG-GYKGAGEGG
Mvan_5183|M.vanbaalenii_PYR-1       AYDDAGNPVASTFVDYLLPTATEVPPIEFGHVEIPGPGVG-GYKGAGEGG
Rv0373c|M.tuberculosis_H37Rv        AFDEDGNCLGGSLMDYLIPTALEVPHLETGHTVTPSPHHPIGAKGIGESA
Mb0380c|M.bovis_AF2122/97           AFDEDGNCLGGSLMDYLIPTALEVPHLETGHTVTPSPHHPIGAKGIGESA
MMAR_0657|M.marinum_M               AFDEDGNCLGGSLMDYLIPTALEVPHLETGHTVTPSPHHPIGAKGIGESA
MUL_0115|M.ulcerans_Agy99           AFDEDGNCLGGSLMDYLIPTALEVPHLETGHTVTPSPHHPIGAKGIGESA
MSMEG_0746|M.smegmatis_MC2_155      AFDEDGNCLGGSLMDYLIPTAMEVPHFETGHTVTPSPHHPIGAKGIGESA
TH_0176|M.thermoresistible__bu      GFDEDGNCLGGSLMDYLIPTAMEVPTLETGFTVTPSPHHPIGAKGIGESA
MAB_2925c|M.abscessus_ATCC_199      LVHD-GFVSTTALRNYHIPRLVDVPDTEVYFADTYDTFGPLGAKSMSESP
                                      .: *     :: :* :*   :**  *  ..   ..    * *. .*. 

Mflv_1573|M.gilvum_PYR-GCK          AIGSPPAVINAVNDALAPLGVTLTQLPATPATIVELIDAASRKDH-
Mvan_5183|M.vanbaalenii_PYR-1       AIGSPPAVINAINDALAPLGVTLTQLPATPATIVELIERAG-KDH-
Rv0373c|M.tuberculosis_H37Rv        TVGSPPAVVNAVVDALAPFGVRHADMPLTPSRVWEAMQGRATPPI-
Mb0380c|M.bovis_AF2122/97           TVGSPPAVVNAVVDALAPFGVRHADMPLTPSRVWEAMQGRATPPI-
MMAR_0657|M.marinum_M               TVGSPPAVVNAVVDALAPYGVRHADMPLTPSRVWEAMQGRATPPI-
MUL_0115|M.ulcerans_Agy99           TVGSPPAVVNAVVDALAPYGVRHADMPLTPSRVWEAMQGRATPPI-
MSMEG_0746|M.smegmatis_MC2_155      TVGSPPAVVNAVVDALAPYGVRHADMPLTPSRVWEAMQGRATPPI-
TH_0176|M.thermoresistible__bu      TVGSPPAVVNAVVDALAPFGVRHVDMPLTPSRVWEAMQGRAQPSI-
MAB_2925c|M.abscessus_ATCC_199      YNPVAPALANAIRDAVG---VRVYRLPMNAARVWRVINDSGGGESS
                                        .**: **: **:.   *    :* ..: : . ::  .