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MSITLPGLRAPSSGNGLASLRSPSVLRTEVLAGLVVALALIPEAIAFSVIAGVDPRVGLFSTVTMAITIA FTGGRPAMITAATAAVALVVAPVAREFGVGYLVATILLAGVIQMLLALFGVAKLMRFIPRSVMVGFVNAL AILVFVSQLQHLVDVPWLVYALTAVGIAVMFLLPKVTTAVPAPLVVVLVLTVAVVAFGWDVPDVGDQGAL PDSLPVPGLPHVPLTLHTLQVIAPYAFGAALVGLLESLMTAKLVDDITDTPSNKTREACGQGTANVVTAL FGGMGGCAVVGQTMMNVKVAGARTRLSTLLTGVFVLILVLALGDLVGRIPMAALVAVMIVVSFATFDWHS ITPRTLKVLPRSETLIMLITVACTVATGNLAIGVSVGVLAAMVAFARRVAHFTSVSAEPGPDDSRTYRVR GDLFFVSSNDLVHQFDYAGDPDEVVIDMSGVSLWDASSVATLDAIRLKYSSRGKTVAFTGLDGESLDRLN RMSGRLGV
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. smegmatis MC2 155 | MSMEG_1235 | - | - | 100% (498) | sulfate permease |
| M. smegmatis MC2 155 | MSMEG_1448 | - | 0.0 | 67.08% (480) | integral membrane transporter |
| M. smegmatis MC2 155 | MSMEG_6453 | - | 6e-59 | 31.80% (500) | sulfate permease |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb1734 | - | 3e-47 | 29.56% (450) | transmembrane protein |
| M. gilvum PYR-GCK | Mflv_1119 | - | 8e-52 | 30.85% (496) | sulphate transporter |
| M. tuberculosis H37Rv | Rv1707 | - | 3e-47 | 29.56% (450) | transmembrane protein |
| M. leprae Br4923 | MLBr_02279 | - | 9e-34 | 25.67% (483) | putative transmembrane transport protein |
| M. abscessus ATCC 19977 | MAB_4448 | - | 2e-42 | 28.25% (531) | putative sulfate transporter |
| M. marinum M | MMAR_4750 | - | 1e-177 | 65.84% (486) | integral membrane transporter |
| M. avium 104 | MAV_0121 | - | 3e-37 | 27.99% (418) | carbonate dehydratase |
| M. thermoresistible (build 8) | TH_2104 | - | 4e-53 | 29.70% (495) | sulfate permease |
| M. ulcerans Agy99 | MUL_0321 | - | 1e-174 | 65.02% (486) | integral membrane transporter |
| M. vanbaalenii PYR-1 | Mvan_1159 | - | 0.0 | 67.98% (481) | sulphate transporter |
CLUSTAL 2.0.9 multiple sequence alignment
Mb1734|M.bovis_AF2122/97 ---------------------------MLQRIARELLSGVAVAIVALPLA
Rv1707|M.tuberculosis_H37Rv ---------------------------MLQRIARELLSGVAVAIVALPLA
Mflv_1119|M.gilvum_PYR-GCK --------MITIGRLGRLLPQRSDYTDLRRSWRADLLAGVTVGVVALPLA
TH_2104|M.thermoresistible__bu ------VIATAKENLIRLLPSRRDYAELPRSWRRDILAGITVGVVALPLA
MMAR_4750|M.marinum_M ---------------------MLAALRSPTRLRTEVLAGLVVALALIPEA
MUL_0321|M.ulcerans_Agy99 MSSQQVSAVPTIRKAGDPSTAVLAALRSPTRLRTEVLAGLVVALALIPEA
Mvan_1159|M.vanbaalenii_PYR-1 MGTMVEAITP------QQEQSVLAALRSPRRLRTEVLGGLVVALALIPEA
MSMEG_1235|M.smegmatis_MC2_155 MSITLPGLRAP------SSGNGLASLRSPSVLRTEVLAGLVVALALIPEA
MLBr_02279|M.leprae_Br4923 ---------------------------MRSAIRYDLPASLVVFLVALPLS
MAV_0121|M.avium_104 -------------------MSTSRSERLREVLRYDLPASLVVFLVALPLS
MAB_4448|M.abscessus_ATCC_1997 ----------------MPSAPGLFESYDAIKARRDVIAGLTVAAISLPQA
:: ..:.* :* :
Mb1734|M.bovis_AF2122/97 IAFGITATGTSQGALIGLYGAIFAGFFAAVFGGTPGQVTGPTGPITVVAT
Rv1707|M.tuberculosis_H37Rv IAFGITATGTSQGALIGLYGAIFAGFFAAVFGGTPGQVTGPTGPITVVAT
Mflv_1119|M.gilvum_PYR-GCK LAFGISSG---VGAAAGLITAVVAGLVAAVFGGSSVQVSGPTGAMAVVLA
TH_2104|M.thermoresistible__bu LAFGISSG---VGAAAGLITAVVAGLVAAVFGGSHIQVSGPTGAMAVILA
MMAR_4750|M.marinum_M ISFSIIAG---VDPRVGLFASFTMAVTIAVVGGRPAMISAATGAIALVIA
MUL_0321|M.ulcerans_Agy99 ISFSIIAG---VDPRVGLFASFTMAVTIAVVGGRLAMISAATGAIALVIA
Mvan_1159|M.vanbaalenii_PYR-1 ISFSIIAG---VDPRVGLFASFTMAVTIAIVGGRPAMISAATGAVALVIA
MSMEG_1235|M.smegmatis_MC2_155 IAFSVIAG---VDPRVGLFSTVTMAITIAFTGGRPAMITAATAAVALVVA
MLBr_02279|M.leprae_Br4923 LGIAIASD---TPVLAGLIAAIVGGIVAGALGGSPLQVSGPAAGLTVVIA
MAV_0121|M.avium_104 LGIAIASD---APVLAGLIAAIVGGIVGGWLGGSPLQVSGPAAGLTVVVA
MAB_4448|M.abscessus_ATCC_1997 MAYALIAG---VDPKYGVYSAIVVTAIASIFGSSSHLINGPTSAISLLVF
:. .: : *: :. . *. :...:. ::::
Mb1734|M.bovis_AF2122/97 ATIAEHG-------LEGAFFAFILAGVFQILFGACRLGSLIRYVPHPVIS
Rv1707|M.tuberculosis_H37Rv ATIAEHG-------LEGAFFAFILAGVFQILFGACRLGSLIRYVPHPVIS
Mflv_1119|M.gilvum_PYR-GCK PIVAMHG-------LGSIALVTVLAGLLVLLAGVTGLGRAVTFIPWPVIE
TH_2104|M.thermoresistible__bu PIVAQHG-------LTSIALVTVLAGLIVLAAGITGLGRAVTFIPWPVIE
MMAR_4750|M.marinum_M PLAREHG-------ADYFIAAVILAGLVQITLSLLGVARLMRFIPRSVMV
MUL_0321|M.ulcerans_Agy99 PLAREQG-------ADYFIAAVILAGLVQITLSLLGVARLMRFIPRSVMV
Mvan_1159|M.vanbaalenii_PYR-1 PLAHSHG-------LDYLIAAVILAGVLQLLLGGLGVAKLMRFVPRSVMV
MSMEG_1235|M.smegmatis_MC2_155 PVAREFG-------VGYLVATILLAGVIQMLLALFGVAKLMRFIPRSVMV
MLBr_02279|M.leprae_Br4923 DLISDFG-------WGVTCFITVAAGVLQVLLGLSRVARAALAISPVVVH
MAV_0121|M.avium_104 DVVAEFG-------WGVTCFITVVAGVLQVLLGFSRIARAALAISPVVVH
MAB_4448|M.abscessus_ATCC_1997 SSLAFLDPENRTGLFEALFLLGVLVGTIQILIAVFKLGDLTRYISESVVI
. : .* . : . :. :. *:
Mb1734|M.bovis_AF2122/97 GFMGGIAILIIMTQLDQVRSS-------SLLVLVTVVLLLA-----SGRF
Rv1707|M.tuberculosis_H37Rv GFMGGIAILIIMTQLDQVRSS-------SLLVLVTVVLLLA-----SGRF
Mflv_1119|M.gilvum_PYR-GCK GFTLGIAAIIFLQQIPAAFAAGGPPGERTLPAAWHVVTHAD-----WSEA
TH_2104|M.thermoresistible__bu GFTLGIAAIIFLQQVPAAFATEAPAGQRTLVAAWHVVTHAD-----WTAA
MMAR_4750|M.marinum_M GFVNALAILIFLSQLPHLLGVP----------------------------
MUL_0321|M.ulcerans_Agy99 GFVNALAILIFLSQVPHLLGVP----------------------------
Mvan_1159|M.vanbaalenii_PYR-1 GFVNALAILIFMSQVPHLLGVP----------------------------
MSMEG_1235|M.smegmatis_MC2_155 GFVNALAILVFVSQLQHLVDVP----------------------------
MLBr_02279|M.leprae_Br4923 AMLAGVGITIALQQAHVLLGGKSKSTAWHNAIGLPSQILGA-----HRPG
MAV_0121|M.avium_104 AMLAGIGITIALQQVHVLLGGSSKSSAWSNVTGLPAQILGA-----HRPG
MAB_4448|M.abscessus_ATCC_1997 GFMASAALLLAIGQLANAIGVRDKGDGHMQVLQRAWLTLFHGDAVNYRAL
.: . . : : *
Mb1734|M.bovis_AF2122/97 IKAIPPSLLVLVLVSSVLPLAAPWLRDLRAGPVS------INRTVD----
Rv1707|M.tuberculosis_H37Rv IKAIPPSLLVLVLVSSVLPLAAPWLRDLRAGPVS------INRTVD----
Mflv_1119|M.gilvum_PYR-GCK VKSLGVIAFVVALMVALPRIHRAIPESLAAVVGATVAVGVLGISVA----
TH_2104|M.thermoresistible__bu VKTLSVVSLVALLMVVLPRLHRSIPESLTAVVAATVIVTVFGISVA----
MMAR_4750|M.marinum_M PVVYPFVIVGLLLMVFLPKLTTVVPAPLVAIVVLTAAAVAFSVEIP----
MUL_0321|M.ulcerans_Agy99 AVVYPFVIVGLLLMVFLPKLTTVVPAPLVAIVVLTAAAVAFSVEIL----
Mvan_1159|M.vanbaalenii_PYR-1 WLVYPMVAVGILVIVALPKLTAAIPGPLVAIVLLTAAAIGFGWSVP----
MSMEG_1235|M.smegmatis_MC2_155 WLVYALTAVGIAVMFLLPKVTTAVPAPLVVVLVLTVAVVAFGWDVP----
MLBr_02279|M.leprae_Br4923 VILGVLVITILIAWRWVPARVARIPGPLVAIVVTTLVSVVFPFHVS----
MAV_0121|M.avium_104 LVLGLLVIAILVAWRWVPARLAIVPGPLVAIVVVTIISMVLPFKVS----
MAB_4448|M.abscessus_ATCC_1997 FLSVTAVALAVLLRRLVQRYELPQIDMLLVLIVTAVIAYAYGWTVPDGTG
: * . :
Mb1734|M.bovis_AF2122/97 --YIG---EIPQAMPSFDFPQVANS--TMLQVLLSAVAIALLGSLDSLLT
Rv1707|M.tuberculosis_H37Rv --YIG---EIPQAMPSFDFPQVANS--TMLQVLLSAVAIALLGSLDSLLT
Mflv_1119|M.gilvum_PYR-GCK --TIG---ELPSHLPAPMLPQIVPG--ALRDLFGAALAIAALAAIESLLS
TH_2104|M.thermoresistible__bu --TIG---ELPSQLPTPVLPQADMG--AMQTLLGAALAIAALAAIESLLS
MMAR_4750|M.marinum_M --NVGDEGQLPSSLPTLLVPHVPFALETLSIIGPYALAMALVGLLESLLT
MUL_0321|M.ulcerans_Agy99 --NVGDEGQLPSSLPTLLVPHVPFALETLSIIGPYALAMALVGLLESLLT
Mvan_1159|M.vanbaalenii_PYR-1 --DVGDEGQLPSSLPSLLIPDVPLTFDTLRIIAPYALAMALVGLLESLMT
MSMEG_1235|M.smegmatis_MC2_155 --DVGDQGALPDSLPVPGLPHVPLTLHTLQVIAPYAFGAALVGLLESLMT
MLBr_02279|M.leprae_Br4923 --RIQ--VDNRSSLDVLQLPKLPDG--HWGAVVLGVITVALIASVESLLS
MAV_0121|M.avium_104 --RIE--LDG-SVLDAVRLPSLPHG--NWGAVAIAVITVTLITSVQSLLT
MAB_4448|M.abscessus_ATCC_1997 HTDVKISGKIPASLPEFHIPEVQVS--TLGELSHGALAIAFIGLIEALSI
: : .* : .. : : :::*
Mb1734|M.bovis_AF2122/97 SLVMDNIRGTR-HRSNKELIGQGIGNIAAGLFGGLAGAGATVRSVVNVRN
Rv1707|M.tuberculosis_H37Rv SLVMDNIRGTR-HRSNKELIGQGIGNIAAGLFGGLSGAGATVRSVVNVRN
Mflv_1119|M.gilvum_PYR-GCK ARVAATMAPTGPYDPDRELVGQGLASVASGAFGGMPATGAIARTAVNVRS
TH_2104|M.thermoresistible__bu ARVAATMSATGPYHPDRELVGQGMASVASGLFGGMPATGAIARTAVNVRS
MMAR_4750|M.marinum_M AKLVDDITDTH-SNKTREAWGQGVANVVTGFFGGMGGCAMIGQTMINVKV
MUL_0321|M.ulcerans_Agy99 AKLVDDITDTH-SNKTREAWGQGVANVVTGFFGGMGGCAMIGQTMINVKV
Mvan_1159|M.vanbaalenii_PYR-1 AKLVDDITDTH-SDKSREAVGQGVANVVTGFFGGMGGCAMIGQTMINVKV
MSMEG_1235|M.smegmatis_MC2_155 AKLVDDITDTP-SNKTREACGQGTANVVTALFGGMGGCAVVGQTMMNVKV
MLBr_02279|M.leprae_Br4923 AVSLDKMHNGPRTDLNRELIGQGAANIVSGAIGGLPITGVIVRSSTNVIA
MAV_0121|M.avium_104 AVSIDRMHTGPRTDFNRELIGQGAANIASGALGGLPIAGVIVRSSANVNA
MAB_4448|M.abscessus_ATCC_1997 AKAIAHHTGQQ-IDYNRQILAEGLANLAGGFFQSLPGSGSLSRSAINYQS
: :: .:* ..:. . : .: . :: *
Mb1734|M.bovis_AF2122/97 -GGQTALSAATHSVVLFVFVAGLGAVVQYIPLAVLSGILILVAVGMFDWH
Rv1707|M.tuberculosis_H37Rv -GGQTALSAATHSVVLFVFVAGLGAVVQYIPLAVLSGILILVAVGMFDWH
Mflv_1119|M.gilvum_PYR-GCK -GARTRLAAVVHSVVLLGVVYLATGPVAAIPLAALSGVLMVTSFRMISRS
TH_2104|M.thermoresistible__bu -GARTRLAAIVHSLVLLAVVYLATGPVSAIPLSALAGVLMVTSFRMVSLH
MMAR_4750|M.marinum_M SGARTRISTFLAGLFLLGLVVGLGDVVALIPMAALVAVMIMVSVGTMDWH
MUL_0321|M.ulcerans_Agy99 PGARTRISTFLAGLFLLGLVVGLGDVVALIPMAALVAVMIMVSVGTMDWH
Mvan_1159|M.vanbaalenii_PYR-1 SGARTRISTFLAGAFLLGLVVGLGDLVAQIPMAALVAVMIMVSVATLDWH
MSMEG_1235|M.smegmatis_MC2_155 AGARTRLSTLLTGVFVLILVLALGDLVGRIPMAALVAVMIVVSFATFDWH
MLBr_02279|M.leprae_Br4923 -GAKSRASSIMHGIWILLFTIPFAGLVDQIPSAALAGLLIVVGVQLLKPA
MAV_0121|M.avium_104 -GAKTRASTIMHGFWVLVFAVPFAGLVEKIPTAALAGLLIVIGIELLKPA
MAB_4448|M.abscessus_ATCC_1997 -GAATRFSGIVSAATVTIALLLFAPLLRYIPQAALAGLLLVTAVRLVDFH
*. : : . : : ** :.* .:::: .. ..
Mb1734|M.bovis_AF2122/97 AMR--KAHVSPRGDVIVMFTTMIITVVVD-LTIAVMVGIALSLLVHRLRS
Rv1707|M.tuberculosis_H37Rv AMR--KAHVSPRGDVIVMFTTMIITVVVD-LTIAVMVGIALSLLVHRLRS
Mflv_1119|M.gilvum_PYR-GCK TMR--KILTSTRSDATTFVLTAVVTVCFD-LIEAVQIGILVAAFFALRSV
TH_2104|M.thermoresistible__bu TAR--RILRSTRSDALTFVLTALVTITFD-LIEAVQIGVLVAAFFALRNV
MMAR_4750|M.marinum_M SIAPATLRRMPRSETLVMLATVVVTVATHNLAYGVVAGVLTAMVLFARRV
MUL_0321|M.ulcerans_Agy99 SIAPATLRRMPRSETLVMLATVVVTVATHNLAYGVVAGVLTAMVLFARRV
Mvan_1159|M.vanbaalenii_PYR-1 SINPKTLRRMPKSETLVMVSTVAVTVATHNLAYGVAVGTLAAMVLFARRV
MSMEG_1235|M.smegmatis_MC2_155 SITPRTLKVLPRSETLIMLITVACTVATGNLAIGVSVGVLAAMVAFARRV
MLBr_02279|M.leprae_Br4923 HIET-----ALRNGDLAVYLVTAVCVVFLNLLHGVMIGLAVAIALTGWRV
MAV_0121|M.avium_104 HIET-----ALRNGDLAIYLVTVTSVIFLNLLHGVLIGLLLAVVVTGWRV
MAB_4448|M.abscessus_ATCC_1997 RLVY--AIKASRYDAGLVIITALVGVAVN-LDTAVLVGVVLSILLFVPRA
: . . : * .* * :
Mb1734|M.bovis_AF2122/97 RQRKAKVTQDDTG-------------------TYRIDGPLSFLSVDGVFG
Rv1707|M.tuberculosis_H37Rv RQRKAKVTQDDTG-------------------TYRIDGPLSFLSVDGVFG
Mflv_1119|M.gilvum_PYR-GCK ARRSSVVREELPAPHRPGDEEI---------ALLRLDGAMFFGAAERISN
TH_2104|M.thermoresistible__bu ARRSGVTREELPGEPQPGDERI---------ALLRLEGSMFFGVAERMSS
MMAR_4750|M.marinum_M AHFMTVERIVESDTGSAAETV-----------VYRVSGELFFASSNDLVY
MUL_0321|M.ulcerans_Agy99 AHFMTVERIVESDTGSAAETV-----------VYRVSCELFFASSNDLVY
Mvan_1159|M.vanbaalenii_PYR-1 AHFT---EVVPVDSG-AADTR-----------VYVVTGELFFASSNDMVY
MSMEG_1235|M.smegmatis_MC2_155 AHFTS----VSAEPG-PDDSR-----------TYRVRGDLFFVSSNDLVH
MLBr_02279|M.leprae_Br4923 IRARVEAQPVGDEWH------------------VLVAGACTFLALPRLTR
MAV_0121|M.avium_104 VRARIEAEPVGDGWH------------------VVIEGACTFLALPRLTG
MAB_4448|M.abscessus_ATCC_1997 AKLKAAELVVTDEGVIRERTPQDRPTGAGAPVIYDLEGELFFGAAPELDR
: : * :
Mb1734|M.bovis_AF2122/97 SLR----DGRED----VSLDLQHVTYLDTSGAQALLYFIDHSEKDGVAVS
Rv1707|M.tuberculosis_H37Rv SLR----DGRED----VSLDLQHVTYLDTSGARALLYFIDHSEKDGVAVS
Mflv_1119|M.gilvum_PYR-GCK AIV----DGDHPRTSVVIIRMSQLGMLDATGANTLAQICTELEARGITVI
TH_2104|M.thermoresistible__bu TIS----EIEADDISVVIIRLSQLGTLDATGANSLAQIATELERRGITVI
MMAR_4750|M.marinum_M QFN----YVDDPDN--VVIDMSQSHIWDASTVAALDAIITKYHAKGRCVE
MUL_0321|M.ulcerans_Agy99 QFN----YVDDPDN--VVIDMSQSHIWDASTVAALDAIITKYHAKGRCVE
Mvan_1159|M.vanbaalenii_PYR-1 QFD----YAGDPDN--IVIDMSAAHIWDASTVATLDAVTTKYAAKGKTVT
MSMEG_1235|M.smegmatis_MC2_155 QFD----YAGDPDE--VVIDMSGVSLWDASSVATLDAIRLKYSSRGKTVA
MLBr_02279|M.leprae_Br4923 VLA----SVPPCTR--VTVNISVN-YLDHAAHQAIHDWQRQHHATGGTVH
MAV_0121|M.avium_104 VLA----SIPERTS--VTVHLLTN-YLDHAAHQAIGDWQRRHCATGGTVE
MAB_4448|M.abscessus_ATCC_1997 YLESLHTRIRDEHLKVVILRLKRVRHPDVVCIERLEHFIREQQQLGVTVL
: : : : * : . * *
Mb1734|M.bovis_AF2122/97 IKRIPPRLESQLTALADNEQRDKLRTVLESA-------------------
Rv1707|M.tuberculosis_H37Rv IKRIPPRLESQLTALADNEQRDKLRTVLESA-------------------
Mflv_1119|M.gilvum_PYR-GCK IKGVRPEHSALLANVGVFESLRHERHLVDTLDEAIEHARTHARRQPH---
TH_2104|M.thermoresistible__bu IKGVQPEHSKLLSNVGVFESLRHEKHLIDSLEDAIEHARSHVARQQTART
MMAR_4750|M.marinum_M IIGLNQDSAERHGRLSGQFGAEH---------------------------
MUL_0321|M.ulcerans_Agy99 IIGLNQDSAERHGRLSGQFGAEH---------------------------
Mvan_1159|M.vanbaalenii_PYR-1 IVGMNDSSAQRHAQLSGQLTGG----------------------------
MSMEG_1235|M.smegmatis_MC2_155 FTGLDGESLDRLNRMSGRLGV-----------------------------
MLBr_02279|M.leprae_Br4923 INGVVETGHFSRCAMGDLIGPEQQPEAAA---------------------
MAV_0121|M.avium_104 VRDTTEPAARRRNSHLSLVEQVSSPGGA----------------------
MAB_4448|M.abscessus_ATCC_1997 LAGVRPDSLALLENVGFTHWLPPEQVFPEEEKEFSATLRAVRYAQSRLEE
.
Mb1734|M.bovis_AF2122/97 ----------------
Rv1707|M.tuberculosis_H37Rv ----------------
Mflv_1119|M.gilvum_PYR-GCK ----------------
TH_2104|M.thermoresistible__bu TS--------------
MMAR_4750|M.marinum_M ----------------
MUL_0321|M.ulcerans_Agy99 ----------------
Mvan_1159|M.vanbaalenii_PYR-1 ----------------
MSMEG_1235|M.smegmatis_MC2_155 ----------------
MLBr_02279|M.leprae_Br4923 ----------------
MAV_0121|M.avium_104 ----------------
MAB_4448|M.abscessus_ATCC_1997 EPPNPAANPEKLYYLV