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SKRPASGGNPYLNLGVLAVVVAVMCLLPLMTSPYYVRVATGVALWAGIALSWNVICGYAGYISFGHVAFF GIGAYTTAILMQPQHDWDFWATLPVAAVVAGAVAALVGWPALRLKGAYFAIATWALAEAVRELTTVVKFT GGSGGLSTPIRADDNFFFYTMLGASAIAYAVCYLLLERSKFGFKVKAVRDNEIAARAQGINTNLVKIQAF VLSAVIPAVLGGINAYWITFINPQSVLNTLITDQLVVMVLVGGLGHAWGPALGATAMFLLQEQLRVSYGE TTAYIIIVGAIVMLIVLFLPDGLVSLGRRARRMRLIRQYLGRARDDLVKTEARG*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. smegmatis MC2 155 | MSMEG_1219 | - | - | 100% (335) | ABC-type transport system permease protein II |
| M. smegmatis MC2 155 | MSMEG_3249 | - | 6e-25 | 26.57% (335) | branched-chain amino acid ABC transporter, permease protein |
| M. smegmatis MC2 155 | MSMEG_6878 | - | 2e-24 | 28.33% (300) | inner-membrane translocator |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | - | - | - | - | - |
| M. gilvum PYR-GCK | Mflv_3572 | - | 2e-23 | 27.39% (303) | inner-membrane translocator |
| M. tuberculosis H37Rv | - | - | - | - | - |
| M. leprae Br4923 | MLBr_00397 | - | 7e-05 | 22.57% (257) | putative transporter protein |
| M. abscessus ATCC 19977 | MAB_2624c | - | 7e-26 | 28.10% (331) | high-affinity branched-chain amino acid ABC transporter (LivM) |
| M. marinum M | - | - | - | - | - |
| M. avium 104 | - | - | - | - | - |
| M. thermoresistible (build 8) | TH_3840 | - | 3e-28 | 28.65% (349) | PUTATIVE branched-chain amino acid ABC transporter, permease |
| M. ulcerans Agy99 | - | - | - | - | - |
| M. vanbaalenii PYR-1 | Mvan_2843 | - | 1e-23 | 28.38% (303) | inner-membrane translocator |
CLUSTAL 2.0.9 multiple sequence alignment
Mflv_3572|M.gilvum_PYR-GCK -------------------------MTRVMEWWDGLTRAQKWVFGIVLFA
Mvan_2843|M.vanbaalenii_PYR-1 ---------------MSTVEKAGAVWARVMDWWDGLTRAQKWVFGIILFA
TH_3840|M.thermoresistible__bu ------------------VNRLLAPGDVVRRWWDSRTRGHKWAVGLLGFG
MAB_2624c|M.abscessus_ATCC_199 ----------------MSAARALAPGDSIRRWWSELARPVQWVYGVVGFA
MSMEG_1219|M.smegmatis_MC2_155 ---------------------------MSKRPASGGNPYLNLGVLAVVVA
MLBr_00397|M.leprae_Br4923 MDHTTKCDAEQYFQAIVTSMADGVIVVDIDGRIESINPAATRILGLRAHD
.
Mflv_3572|M.gilvum_PYR-GCK GIALSPLFKPGFIDTPGISFGGTMAQFAMVAIIAIGLNVVVGQAG-----
Mvan_2843|M.vanbaalenii_PYR-1 GIALSPLFTPGFIDTPGISFGGTMAQFAMVAIIAIGLNVVVGQAG-----
TH_3840|M.thermoresistible__bu VLALLPLYTPPFLDTPGISFGGTMAQFAMFALIAIGLNVVVGQAG-----
MAB_2624c|M.abscessus_ATCC_199 LLALLPVWKIPYLDTPNTSFGGVMAQFAMVALIAIGLNVVVGQAG-----
MSMEG_1219|M.smegmatis_MC2_155 VMCLLPLMTSPYYVR-------VATGVALWAGIALSWNVICGYAG-----
MLBr_00397|M.leprae_Br4923 VVDMKHGHPFCFYDTDNQRVDLEREVMRVVRREVTTVSKVVGIDQHSGQR
: : : . : . . : *
Mflv_3572|M.gilvum_PYR-GCK ---LLDLGYVGFYAVGAYTVALLTSPESPWNQMSPKGILTTPWAWLACVP
Mvan_2843|M.vanbaalenii_PYR-1 ---LLDLGYVGFYAVGAYTVALLTSPESPWNKLGPTGFFSTPWAWLSCVP
TH_3840|M.thermoresistible__bu ---LLDLGYVGFYAVGAYTVALLTSPESPWNRMGWTVFFSSDWAWLSCVP
MAB_2624c|M.abscessus_ATCC_199 ---LLDLGYVGFYAIGAYTVALLTSPDSPWNRMGTSAFFSSDWAWLSCLP
MSMEG_1219|M.smegmatis_MC2_155 ---YISFGHVAFFGIGAYTTAILMQP-------------QHDWDFWATLP
MLBr_00397|M.leprae_Br4923 LWLSVNVSLLAYKAPPHSALVVSFSDISAHHLSIERLTYEATHDCLTGLA
:... :.: . : .: . : :.
Mflv_3572|M.gilvum_PYR-GCK ------------------------------LAMAVTALSGLILGTPTLRL
Mvan_2843|M.vanbaalenii_PYR-1 ------------------------------LAMAVTALSGLILGTPTLRL
TH_3840|M.thermoresistible__bu ------------------------------LAMAVTAFSGLIIGTPTLRL
MAB_2624c|M.abscessus_ATCC_199 ------------------------------IAVAITACFGLILGTPTLRL
MSMEG_1219|M.smegmatis_MC2_155 ------------------------------VAAVVAGAVAALVGWPALRL
MLBr_00397|M.leprae_Br4923 NRRFAEDQITKSLQHDERSRLAAVLLLDLDDFKVINDSLGHDVGDAVLQT
.: . :* ..*:
Mflv_3572|M.gilvum_PYR-GCK RGDYLAIVTLGFGEIIRLLADNLADVTNGPR-------------------
Mvan_2843|M.vanbaalenii_PYR-1 RGDYLAIVTLGFGEIIRLLADNLADITNGPR-------------------
TH_3840|M.thermoresistible__bu RGDYLAIVTLGFGEIIRLVADNLSGVTNGAR-------------------
MAB_2624c|M.abscessus_ATCC_199 RGDYLAIVTLGFGEIIRLLADNL-DVTNGPR-------------------
MSMEG_1219|M.smegmatis_MC2_155 KGAYFAIATWALAEAVR----ELTTVVKFTG-------------------
MLBr_00397|M.leprae_Br4923 VAQRLRSAVRPDDVVARLGGDEFIVLLRGPLSDMNANDVAKRLHTTLSES
. : .. * :: : . .
Mflv_3572|M.gilvum_PYR-GCK ----------GLNEVAFPHFLESEQHPEGVFSVSN---------------
Mvan_2843|M.vanbaalenii_PYR-1 ----------GLNEVAFPHFLESDQHPEGVFSVSN---------------
TH_3840|M.thermoresistible__bu ----------GLHQVAYPRVGESERLPDGVFSSGN---------------
MAB_2624c|M.abscessus_ATCC_199 ----------GLHKVAYPHVGEQHVHGGGVFSSAN---------------
MSMEG_1219|M.smegmatis_MC2_155 ----------GSGGLSTPIRADDN----FFFYTML---------------
MLBr_00397|M.leprae_Br4923 LVVDQLTVPIGASVGILEVRPDDRRRAADILRDADSAMYAAKNKKQCAVT
* :. .:
Mflv_3572|M.gilvum_PYR-GCK -------------------SGGDANYGAWWFWLGLILIVGILLLVGNLER
Mvan_2843|M.vanbaalenii_PYR-1 -------------------SGGDANYGTWWFWLGLILIVGILLLVGNLER
TH_3840|M.thermoresistible__bu -------------------SAGAANYGTWWFWLGLVLIAVILVLVGNLER
MAB_2624c|M.abscessus_ATCC_199 -------------------SGGHLNYGVWWYWLGLCLIAAVLVLMGNLER
MSMEG_1219|M.smegmatis_MC2_155 -------------------GASAIAYAVCYLLL---------------ER
MLBr_00397|M.leprae_Br4923 PQQLVPFVALIALFVFFTAAAGAKFYAPSNLLVILQQTVVLAIVGYGMTF
... *. :
Mflv_3572|M.gilvum_PYR-GCK SRVG------RAWIAVREDEDAAEVMGVNAFKFKLWAFTIGAAIGGLSGA
Mvan_2843|M.vanbaalenii_PYR-1 SRVG------RAWIAVREDEDAAEVMGVNAFKFKLWAFTIGAAIGGLSGA
TH_3840|M.thermoresistible__bu SRVG------RAWIAIREDEDAAEVMGVNTFKFKVWAFVIGAAIGGLSGA
MAB_2624c|M.abscessus_ATCC_199 SRVG------RSWVAIREDEDAAEMMGVPTFRFKLWAFVIGASIGGLSGA
MSMEG_1219|M.smegmatis_MC2_155 SKFG------FKVKAVRDNEIAARAQGINTNLVKIQAFVLSAVIPAVLGG
MLBr_00397|M.leprae_Br4923 VIMAGSVDLSVGSIVALTGVTAALVAAQNQFAAIVTALLVGLAAGMVNGI
.. . . ** . : *: :. : *
Mflv_3572|M.gilvum_PYR-GCK LYAG-----------------------------------------QVQYV
Mvan_2843|M.vanbaalenii_PYR-1 LYAG-----------------------------------------QVQYV
TH_3840|M.thermoresistible__bu LYAG-----------------------------------------QVQYV
MAB_2624c|M.abscessus_ATCC_199 LYAG-----------------------------------------QVQYV
MSMEG_1219|M.smegmatis_MC2_155 INAY-----------------------------------------WITFI
MLBr_00397|M.leprae_Br4923 VFAYGKIPSFVSTLGMLQVCRGITLMISDSSAKPMPFHGILGAMGAMPWI
: * : ::
Mflv_3572|M.gilvum_PYR-GCK AP-PTFNIINSMLFLCAVVLGGQGNKLG----------------------
Mvan_2843|M.vanbaalenii_PYR-1 AP-PTFNIINSMLFLCAVVLGGQGNKLG----------------------
TH_3840|M.thermoresistible__bu AP-PTFNIINSMLFLCAVVLGGQGNKLG----------------------
MAB_2624c|M.abscessus_ATCC_199 AS-PTFNIINSMLFLCAVVLGGQGNKLG----------------------
MSMEG_1219|M.smegmatis_MC2_155 NPQSVLNTLITDQLVVMVLVGGLGHAWG----------------------
MLBr_00397|M.leprae_Br4923 LIVCLFVTILAGILFQFTMFGRWVKAIGGNERVATLAGVPTRGIKVAIFA
: : : :. .:.* : *
Mflv_3572|M.gilvum_PYR-GCK -----VILGAFIIVYLPNRLLGVHFLGIDMGNLKYLFFG-----------
Mvan_2843|M.vanbaalenii_PYR-1 -----VILGAFIIVYLPNRLLGVHFLGIDMGNLKYLFFG-----------
TH_3840|M.thermoresistible__bu -----VVLGAFVIVYLPNRLLGVELLGVNLGDLKYLFFG-----------
MAB_2624c|M.abscessus_ATCC_199 -----VVVGAFIIVYLPNRLLGVQVQGIDLGNLKYLFFG-----------
MSMEG_1219|M.smegmatis_MC2_155 -----PALGATAMFLLQEQLR----VSYGETTAYIIIVG-----------
MLBr_00397|M.leprae_Br4923 ICGLTAGLGGIVLASRLGAGTPTAATGFEIDVIAAVVIGGTPLTGGLGRL
:*. : . :..*
Mflv_3572|M.gilvum_PYR-GCK ---LALVVLMIFRPQGLFPARQHLLTYARAARKLLRAK-PTDTEPAK---
Mvan_2843|M.vanbaalenii_PYR-1 ---LALVVLMIFRPQGLFPARQHLLTYARAARKLLRAQ-PTDTEPAK---
TH_3840|M.thermoresistible__bu ---LALVVMMIFRPAGLFPARQQLLAYGRSAREMLRAR-PDDREPVSS--
MAB_2624c|M.abscessus_ATCC_199 ---LALVVLMLFRPQGLFPAHQKLMAYWRKTSERLSAQKPDEVEAGA---
MSMEG_1219|M.smegmatis_MC2_155 ---AIVMLIVLFLPDGLVSLGRRARRMRLIRQYLGRARDDLVKTEARG--
MLBr_00397|M.leprae_Br4923 SGTLIGAIIISMLSNGMVFMGVGNAASQIIKGIMLAAAVFVFLQRRKIGI
::: : . *:. *
Mflv_3572|M.gilvum_PYR-GCK --
Mvan_2843|M.vanbaalenii_PYR-1 --
TH_3840|M.thermoresistible__bu --
MAB_2624c|M.abscessus_ATCC_199 --
MSMEG_1219|M.smegmatis_MC2_155 --
MLBr_00397|M.leprae_Br4923 IK