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M. thermoresistible (build 8) TH_3840 (-)

annotation: branched-chain amino acid ABC transporter, permease protein
coordinates: 2121002 - 2122171
length: 390

aa seq not available

Operon Prediction Model: Genebank

Paralogs

species id gene e-value identity (len) annotation
M. thermoresistible (build 8) TH_3840 - - 100% (390) branched-chain amino acid ABC transporter, permease protein
M. thermoresistible (build 8) TH_2330 - 2e-21 25.50% (400) putative membrane protein
M. thermoresistible (build 8) TH_1081 - 2e-11 23.42% (333) ABC transporter branched chain amino acid transport permease

Closest Orthologs (e-value cutoff: 1e-4)

species id gene e-value identity (len) annotation
M. bovis AF2122 / 97 - - - - -
M. gilvum PYR-GCK Mflv_3572 - 1e-176 78.99% (376) inner-membrane translocator
M. tuberculosis H37Rv - - - - -
M. leprae Br4923 MLBr_00397 - 2e-05 20.32% (310) putative transporter protein
M. abscessus ATCC 19977 MAB_2624c - 1e-172 76.30% (384) high-affinity branched-chain amino acid ABC transporter (LivM)
M. marinum M - - - - -
M. avium 104 - - - - -
M. smegmatis MC2 155 MSMEG_3249 - 0.0 83.73% (381) branched-chain amino acid ABC transporter, permease protein
M. ulcerans Agy99 - - - - -
M. vanbaalenii PYR-1 Mvan_2843 - 1e-179 80.32% (376) inner-membrane translocator

CLUSTAL 2.0.9 multiple sequence alignment


Mflv_3572|M.gilvum_PYR-GCK          ------------------------MTRVMEWWD---GLTRAQKWVFGIVL
Mvan_2843|M.vanbaalenii_PYR-1       --------------MSTVEKAGAVWARVMDWWD---GLTRAQKWVFGIIL
TH_3840|M.thermoresistible__bu      -----------------VNRLLAPGDVVRRWWD---SRTRGHKWAVGLLG
MSMEG_3249|M.smegmatis_MC2_155      MSDQHTQQNPGENTSSLVRTLLAPGDIIREQWS---TLPRVAKWAVGVIG
MAB_2624c|M.abscessus_ATCC_199      ---------------MSAARALAPGDSIRRWWS---ELARPVQWVYGVVG
MLBr_00397|M.leprae_Br4923          --MDHTTKCDAEQYFQAIVTSMADGVIVVDIDGRIESINPAATRILGLRA
                                                               :    .             *:  

Mflv_3572|M.gilvum_PYR-GCK          FAGIALSPLFKPGFIDTPG--ISFGGTMAQFAMVAIIAIGLNVVVGQAGL
Mvan_2843|M.vanbaalenii_PYR-1       FAGIALSPLFTPGFIDTPG--ISFGGTMAQFAMVAIIAIGLNVVVGQAGL
TH_3840|M.thermoresistible__bu      FGVLALLPLYTPPFLDTPG--ISFGGTMAQFAMFALIAIGLNVVVGQAGL
MSMEG_3249|M.smegmatis_MC2_155      FGLLALLPLFTPGFLNTPG--ISFGGTMAQFAMVAIIAIGLNVVVGQAGL
MAB_2624c|M.abscessus_ATCC_199      FALLALLPVWKIPYLDTPN--TSFGGVMAQFAMVALIAIGLNVVVGQAGL
MLBr_00397|M.leprae_Br4923          HDVVDMKHGHPFCFYDTDNQRVDLEREVMRVVRREVTTVSKVVGIDQHSG
                                    .  : :       : :* .   .:   : :..   : ::.  * :.* . 

Mflv_3572|M.gilvum_PYR-GCK          LDLGYVGFYAVGAYTVALLTSPESPWNQMSPKGILTTPWAWLACVPLAMA
Mvan_2843|M.vanbaalenii_PYR-1       LDLGYVGFYAVGAYTVALLTSPESPWNKLGPTGFFSTPWAWLSCVPLAMA
TH_3840|M.thermoresistible__bu      LDLGYVGFYAVGAYTVALLTSPESPWNRMGWTVFFSSDWAWLSCVPLAMA
MSMEG_3249|M.smegmatis_MC2_155      LDLGYVGFYAVGAYTVALLTSPSSPWNIVGVDKFLSSDWAWLACVPLAMA
MAB_2624c|M.abscessus_ATCC_199      LDLGYVGFYAIGAYTVALLTSPDSPWNRMGTSAFFSSDWAWLSCLPIAVA
MLBr_00397|M.leprae_Br4923          QRLWLSVNVSLLAYKAPPHSALVVSFSDISAHHLSIERLTYEATHDCLTG
                                      *      :: **...  ::   .:. :.   :     :: :      .

Mflv_3572|M.gilvum_PYR-GCK          VT-----------------------------------------ALSGLIL
Mvan_2843|M.vanbaalenii_PYR-1       VT-----------------------------------------ALSGLIL
TH_3840|M.thermoresistible__bu      VT-----------------------------------------AFSGLII
MSMEG_3249|M.smegmatis_MC2_155      IT-----------------------------------------AIAGLIL
MAB_2624c|M.abscessus_ATCC_199      IT-----------------------------------------ACFGLIL
MLBr_00397|M.leprae_Br4923          LANRRFAEDQITKSLQHDERSRLAAVLLLDLDDFKVINDSLGHDVGDAVL
                                    ::                                            . ::

Mflv_3572|M.gilvum_PYR-GCK          GTPTLRLRGDYLA---IVTLGFGEIIRLLADNLADVTNGPRG--------
Mvan_2843|M.vanbaalenii_PYR-1       GTPTLRLRGDYLA---IVTLGFGEIIRLLADNLADITNGPRG--------
TH_3840|M.thermoresistible__bu      GTPTLRLRGDYLA---IVTLGFGEIIRLVADNLSGVTNGARG--------
MSMEG_3249|M.smegmatis_MC2_155      GTPTLRLRGDYLA---IVTLGFGEIIRLMADNLSDITNGARG--------
MAB_2624c|M.abscessus_ATCC_199      GTPTLRLRGDYLA---IVTLGFGEIIRLLADNL-DVTNGPRG--------
MLBr_00397|M.leprae_Br4923          QTVAQRLRSAVRPDDVVARLGGDEFIVLLRGPLSDMNANDVAKRLHTTLS
                                     * : ***.   .   :. ** .*:* *: . * .:. .  .        

Mflv_3572|M.gilvum_PYR-GCK          ----LNEVAFPH---FLESEQHPEG-------------------------
Mvan_2843|M.vanbaalenii_PYR-1       ----LNEVAFPH---FLESDQHPEG-------------------------
TH_3840|M.thermoresistible__bu      ----LHQVAYPR---VGESERLPDG-------------------------
MSMEG_3249|M.smegmatis_MC2_155      ----LNQVAYPR---LGESEKLPNG-------------------------
MAB_2624c|M.abscessus_ATCC_199      ----LHKVAYPH---VGEQHVHGGG-------------------------
MLBr_00397|M.leprae_Br4923          ESLVVDQLTVPIGASVGILEVRPDDRRRAADILRDADSAMYAAKNKKQCA
                                        :.::: *    .   .    .                         

Mflv_3572|M.gilvum_PYR-GCK          --------------VFSVSNSGGDANYGAWWFWLGLILIVGILLLVGN--
Mvan_2843|M.vanbaalenii_PYR-1       --------------VFSVSNSGGDANYGTWWFWLGLILIVGILLLVGN--
TH_3840|M.thermoresistible__bu      --------------VFSSGNSAGAANYGTWWFWLGLVLIAVILVLVGN--
MSMEG_3249|M.smegmatis_MC2_155      --------------VFSSGNSTGVANYGTWWFWLGLALIVGILLLVGN--
MAB_2624c|M.abscessus_ATCC_199      --------------VFSSANSGGHLNYGVWWYWLGLCLIAAVLVLMGN--
MLBr_00397|M.leprae_Br4923          VTPQQLVPFVALIALFVFFTAAAGAKFYAPSNLLVILQQTVVLAIVGYGM
                                                  :*   .: .  :: .    * :   . :* ::*   

Mflv_3572|M.gilvum_PYR-GCK          -----LERSRVGRAWIAVREDEDAAEVMGVNAFKFKLWAFTIGAAIGGLS
Mvan_2843|M.vanbaalenii_PYR-1       -----LERSRVGRAWIAVREDEDAAEVMGVNAFKFKLWAFTIGAAIGGLS
TH_3840|M.thermoresistible__bu      -----LERSRVGRAWIAIREDEDAAEVMGVNTFKFKVWAFVIGAAIGGLS
MSMEG_3249|M.smegmatis_MC2_155      -----LERSRVGRAWIAIREDEDAAEVMGVNAFKFKLWAFTIGAAIGGLS
MAB_2624c|M.abscessus_ATCC_199      -----LERSRVGRSWVAIREDEDAAEMMGVPTFRFKLWAFVIGASIGGLS
MLBr_00397|M.leprae_Br4923          TFVIMAGSVDLSVGSIVALTGVTAALVAAQNQFAAIVTALLVGLAAGMVN
                                              :. . :.   .  ** : .   *   : *: :* : * :.

Mflv_3572|M.gilvum_PYR-GCK          GALYAG--------------------------------------------
Mvan_2843|M.vanbaalenii_PYR-1       GALYAG--------------------------------------------
TH_3840|M.thermoresistible__bu      GALYAG--------------------------------------------
MSMEG_3249|M.smegmatis_MC2_155      GALYAG--------------------------------------------
MAB_2624c|M.abscessus_ATCC_199      GALYAG--------------------------------------------
MLBr_00397|M.leprae_Br4923          GIVFAYGKIPSFVSTLGMLQVCRGITLMISDSSAKPMPFHGILGAMGAMP
                                    * ::*                                             

Mflv_3572|M.gilvum_PYR-GCK          ----------------------------------QVQYVAPPTFNIINSM
Mvan_2843|M.vanbaalenii_PYR-1       ----------------------------------QVQYVAPPTFNIINSM
TH_3840|M.thermoresistible__bu      ----------------------------------QVQYVAPPTFNIINSM
MSMEG_3249|M.smegmatis_MC2_155      ----------------------------------QVQYVAPQTFNIINSM
MAB_2624c|M.abscessus_ATCC_199      ----------------------------------QVQYVASPTFNIINSM
MLBr_00397|M.leprae_Br4923          WILIVCLFVTILAGILFQFTMFGRWVKAIGGNERVATLAGVPTRGIKVAI
                                                                       .  ..  * .*  ::

Mflv_3572|M.gilvum_PYR-GCK          LFLCAVVLGGQGNKLGVILGA--------FIIVYLPNRLLGVHFLGIDMG
Mvan_2843|M.vanbaalenii_PYR-1       LFLCAVVLGGQGNKLGVILGA--------FIIVYLPNRLLGVHFLGIDMG
TH_3840|M.thermoresistible__bu      LFLCAVVLGGQGNKLGVVLGA--------FVIVYLPNRLLGVELLGVNLG
MSMEG_3249|M.smegmatis_MC2_155      LFLCAVVLGGQGNKLGVIFGA--------FVIVYLPNRLLGVEFLGINLG
MAB_2624c|M.abscessus_ATCC_199      LFLCAVVLGGQGNKLGVVVGA--------FIIVYLPNRLLGVQVQGIDLG
MLBr_00397|M.leprae_Br4923          FAICGLTAGLGGIVLASRLGAGTPTAATGFEIDVIAAVVIGGTPLTGGLG
                                    : :*.:. *  *  *.  .**        * *  :.  ::*      .:*

Mflv_3572|M.gilvum_PYR-GCK          NLKYLFFGLALVVLMI--FRPQGLFPARQHLLTYARAARKLLRAKPTDTE
Mvan_2843|M.vanbaalenii_PYR-1       NLKYLFFGLALVVLMI--FRPQGLFPARQHLLTYARAARKLLRAQPTDTE
TH_3840|M.thermoresistible__bu      DLKYLFFGLALVVMMI--FRPAGLFPARQQLLAYGRSAREMLRARPDDRE
MSMEG_3249|M.smegmatis_MC2_155      DLKYLFFGLALVVLMI--FRPQGLFPARQHLLTYGKAARDLLRATP-VKE
MAB_2624c|M.abscessus_ATCC_199      NLKYLFFGLALVVLML--FRPQGLFPAHQKLMAYWRKTSERLSAQKPDEV
MLBr_00397|M.leprae_Br4923          RLSGTLIGAIIISMLSNGMVFMGVGNAASQIIKGIMLAAAVFVFLQRRKI
                                     *.  ::*  :: ::   :   *:  * .:::     :   :        

Mflv_3572|M.gilvum_PYR-GCK          PAK-
Mvan_2843|M.vanbaalenii_PYR-1       PAK-
TH_3840|M.thermoresistible__bu      PVSS
MSMEG_3249|M.smegmatis_MC2_155      HTS-
MAB_2624c|M.abscessus_ATCC_199      EAGA
MLBr_00397|M.leprae_Br4923          GIIK

species	id	gene	e-value	identity (len)	annotation
M. thermoresistible (build 8)	TH_3840	-	-	100% (390)	branched-chain amino acid ABC transporter, permease protein
M. thermoresistible (build 8)	TH_2330	-	2e-21	25.50% (400)	putative membrane protein
M. thermoresistible (build 8)	TH_1081	-	2e-11	23.42% (333)	ABC transporter branched chain amino acid transport permease