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SAARALAPGDSIRRWWSELARPVQWVYGVVGFALLALLPVWKIPYLDTPNTSFGGVMAQFAMVALIAIGL NVVVGQAGLLDLGYVGFYAIGAYTVALLTSPDSPWNRMGTSAFFSSDWAWLSCLPIAVAITACFGLILGT PTLRLRGDYLAIVTLGFGEIIRLLADNLDVTNGPRGLHKVAYPHVGEQHVHGGGVFSSANSGGHLNYGVW WYWLGLCLIAAVLVLMGNLERSRVGRSWVAIREDEDAAEMMGVPTFRFKLWAFVIGASIGGLSGALYAGQ VQYVASPTFNIINSMLFLCAVVLGGQGNKLGVVVGAFIIVYLPNRLLGVQVQGIDLGNLKYLFFGLALVV LMLFRPQGLFPAHQKLMAYWRKTSERLSAQKPDEVEAGA*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. abscessus ATCC 19977 | MAB_2624c | - | - | 100% (390) | high-affinity branched-chain amino acid ABC transporter (LivM) |
| M. abscessus ATCC 19977 | MAB_2625c | - | 2e-09 | 25.15% (326) | branched chain amino acid ABC transporter |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | - | - | - | - | - |
| M. gilvum PYR-GCK | Mflv_3572 | - | 1e-163 | 73.67% (376) | inner-membrane translocator |
| M. tuberculosis H37Rv | - | - | - | - | - |
| M. leprae Br4923 | MLBr_00397 | - | 6e-06 | 29.14% (151) | putative transporter protein |
| M. marinum M | - | - | - | - | - |
| M. avium 104 | - | - | - | - | - |
| M. smegmatis MC2 155 | MSMEG_3249 | - | 1e-163 | 74.93% (375) | branched-chain amino acid ABC transporter, permease protein |
| M. thermoresistible (build 8) | TH_3840 | - | 1e-172 | 76.30% (384) | PUTATIVE branched-chain amino acid ABC transporter, permease |
| M. ulcerans Agy99 | - | - | - | - | - |
| M. vanbaalenii PYR-1 | Mvan_2843 | - | 1e-164 | 74.86% (370) | inner-membrane translocator |
CLUSTAL 2.0.9 multiple sequence alignment
MSMEG_3249|M.smegmatis_MC2_155 MSDQHTQQNPGENTSSLVRTLLAPGDIIREQWS---TLPRVAKWAVGVIG
TH_3840|M.thermoresistible__bu -----------------VNRLLAPGDVVRRWWD---SRTRGHKWAVGLLG
Mflv_3572|M.gilvum_PYR-GCK ------------------------MTRVMEWWD---GLTRAQKWVFGIVL
Mvan_2843|M.vanbaalenii_PYR-1 --------------MSTVEKAGAVWARVMDWWD---GLTRAQKWVFGIIL
MAB_2624c|M.abscessus_ATCC_199 ---------------MSAARALAPGDSIRRWWS---ELARPVQWVYGVVG
MLBr_00397|M.leprae_Br4923 --MDHTTKCDAEQYFQAIVTSMADGVIVVDIDGRIESINPAATRILGLRA
: . *:
MSMEG_3249|M.smegmatis_MC2_155 FGLLALLPLFTPGFLNTPG--ISFGGTMAQFAMVAIIAIGLNVVVGQAGL
TH_3840|M.thermoresistible__bu FGVLALLPLYTPPFLDTPG--ISFGGTMAQFAMFALIAIGLNVVVGQAGL
Mflv_3572|M.gilvum_PYR-GCK FAGIALSPLFKPGFIDTPG--ISFGGTMAQFAMVAIIAIGLNVVVGQAGL
Mvan_2843|M.vanbaalenii_PYR-1 FAGIALSPLFTPGFIDTPG--ISFGGTMAQFAMVAIIAIGLNVVVGQAGL
MAB_2624c|M.abscessus_ATCC_199 FALLALLPVWKIPYLDTPN--TSFGGVMAQFAMVALIAIGLNVVVGQAGL
MLBr_00397|M.leprae_Br4923 HDVVDMKHGHPFCFYDTDNQRVDLEREVMRVVRREVTTVSKVVGIDQHSG
. : : : :* . .: : :.. : ::. * :.* .
MSMEG_3249|M.smegmatis_MC2_155 LDLGYVGFYAVGAYTVALLTSPSSPWNIVGVDKFLSSDWAWLACVPLAMA
TH_3840|M.thermoresistible__bu LDLGYVGFYAVGAYTVALLTSPESPWNRMGWTVFFSSDWAWLSCVPLAMA
Mflv_3572|M.gilvum_PYR-GCK LDLGYVGFYAVGAYTVALLTSPESPWNQMSPKGILTTPWAWLACVPLAMA
Mvan_2843|M.vanbaalenii_PYR-1 LDLGYVGFYAVGAYTVALLTSPESPWNKLGPTGFFSTPWAWLSCVPLAMA
MAB_2624c|M.abscessus_ATCC_199 LDLGYVGFYAIGAYTVALLTSPDSPWNRMGTSAFFSSDWAWLSCLPIAVA
MLBr_00397|M.leprae_Br4923 QRLWLSVNVSLLAYKAPPHSALVVSFSDISAHHLSIERLTYEATHDCLTG
* :: **... :: .:. :. : :: : .
MSMEG_3249|M.smegmatis_MC2_155 IT-----------------------------------------AIAGLIL
TH_3840|M.thermoresistible__bu VT-----------------------------------------AFSGLII
Mflv_3572|M.gilvum_PYR-GCK VT-----------------------------------------ALSGLIL
Mvan_2843|M.vanbaalenii_PYR-1 VT-----------------------------------------ALSGLIL
MAB_2624c|M.abscessus_ATCC_199 IT-----------------------------------------ACFGLIL
MLBr_00397|M.leprae_Br4923 LANRRFAEDQITKSLQHDERSRLAAVLLLDLDDFKVINDSLGHDVGDAVL
:: . ::
MSMEG_3249|M.smegmatis_MC2_155 GTPTLRLRGDYLA---IVTLGFGEIIRLMADNLSDITNGARG--------
TH_3840|M.thermoresistible__bu GTPTLRLRGDYLA---IVTLGFGEIIRLVADNLSGVTNGARG--------
Mflv_3572|M.gilvum_PYR-GCK GTPTLRLRGDYLA---IVTLGFGEIIRLLADNLADVTNGPRG--------
Mvan_2843|M.vanbaalenii_PYR-1 GTPTLRLRGDYLA---IVTLGFGEIIRLLADNLADITNGPRG--------
MAB_2624c|M.abscessus_ATCC_199 GTPTLRLRGDYLA---IVTLGFGEIIRLLADNL-DVTNGPRG--------
MLBr_00397|M.leprae_Br4923 QTVAQRLRSAVRPDDVVARLGGDEFIVLLRGPLSDMNANDVAKRLHTTLS
* : ***. . :. ** .*:* *: . * .:. . .
MSMEG_3249|M.smegmatis_MC2_155 ----LNQVAYPR---LGESEKLPNG-------------------------
TH_3840|M.thermoresistible__bu ----LHQVAYPR---VGESERLPDG-------------------------
Mflv_3572|M.gilvum_PYR-GCK ----LNEVAFPH---FLESEQHPEG-------------------------
Mvan_2843|M.vanbaalenii_PYR-1 ----LNEVAFPH---FLESDQHPEG-------------------------
MAB_2624c|M.abscessus_ATCC_199 ----LHKVAYPH---VGEQHVHGGG-------------------------
MLBr_00397|M.leprae_Br4923 ESLVVDQLTVPIGASVGILEVRPDDRRRAADILRDADSAMYAAKNKKQCA
:.::: * . . .
MSMEG_3249|M.smegmatis_MC2_155 --------------VFSSGNSTGVANYGTWWFWLGLALIVGILLLVGN--
TH_3840|M.thermoresistible__bu --------------VFSSGNSAGAANYGTWWFWLGLVLIAVILVLVGN--
Mflv_3572|M.gilvum_PYR-GCK --------------VFSVSNSGGDANYGAWWFWLGLILIVGILLLVGN--
Mvan_2843|M.vanbaalenii_PYR-1 --------------VFSVSNSGGDANYGTWWFWLGLILIVGILLLVGN--
MAB_2624c|M.abscessus_ATCC_199 --------------VFSSANSGGHLNYGVWWYWLGLCLIAAVLVLMGN--
MLBr_00397|M.leprae_Br4923 VTPQQLVPFVALIALFVFFTAAAGAKFYAPSNLLVILQQTVVLAIVGYGM
:* .: . :: . * : . :* ::*
MSMEG_3249|M.smegmatis_MC2_155 -----LERSRVGRAWIAIREDEDAAEVMGVNAFKFKLWAFTIGAAIGGLS
TH_3840|M.thermoresistible__bu -----LERSRVGRAWIAIREDEDAAEVMGVNTFKFKVWAFVIGAAIGGLS
Mflv_3572|M.gilvum_PYR-GCK -----LERSRVGRAWIAVREDEDAAEVMGVNAFKFKLWAFTIGAAIGGLS
Mvan_2843|M.vanbaalenii_PYR-1 -----LERSRVGRAWIAVREDEDAAEVMGVNAFKFKLWAFTIGAAIGGLS
MAB_2624c|M.abscessus_ATCC_199 -----LERSRVGRSWVAIREDEDAAEMMGVPTFRFKLWAFVIGASIGGLS
MLBr_00397|M.leprae_Br4923 TFVIMAGSVDLSVGSIVALTGVTAALVAAQNQFAAIVTALLVGLAAGMVN
:. . :. . ** : . * : *: :* : * :.
MSMEG_3249|M.smegmatis_MC2_155 GALYAG--------------------------------------------
TH_3840|M.thermoresistible__bu GALYAG--------------------------------------------
Mflv_3572|M.gilvum_PYR-GCK GALYAG--------------------------------------------
Mvan_2843|M.vanbaalenii_PYR-1 GALYAG--------------------------------------------
MAB_2624c|M.abscessus_ATCC_199 GALYAG--------------------------------------------
MLBr_00397|M.leprae_Br4923 GIVFAYGKIPSFVSTLGMLQVCRGITLMISDSSAKPMPFHGILGAMGAMP
* ::*
MSMEG_3249|M.smegmatis_MC2_155 ----------------------------------QVQYVAPQTFNIINSM
TH_3840|M.thermoresistible__bu ----------------------------------QVQYVAPPTFNIINSM
Mflv_3572|M.gilvum_PYR-GCK ----------------------------------QVQYVAPPTFNIINSM
Mvan_2843|M.vanbaalenii_PYR-1 ----------------------------------QVQYVAPPTFNIINSM
MAB_2624c|M.abscessus_ATCC_199 ----------------------------------QVQYVASPTFNIINSM
MLBr_00397|M.leprae_Br4923 WILIVCLFVTILAGILFQFTMFGRWVKAIGGNERVATLAGVPTRGIKVAI
. .. * .* ::
MSMEG_3249|M.smegmatis_MC2_155 LFLCAVVLGGQGNKLGVIFGA--------FVIVYLPNRLLGVEFLGINLG
TH_3840|M.thermoresistible__bu LFLCAVVLGGQGNKLGVVLGA--------FVIVYLPNRLLGVELLGVNLG
Mflv_3572|M.gilvum_PYR-GCK LFLCAVVLGGQGNKLGVILGA--------FIIVYLPNRLLGVHFLGIDMG
Mvan_2843|M.vanbaalenii_PYR-1 LFLCAVVLGGQGNKLGVILGA--------FIIVYLPNRLLGVHFLGIDMG
MAB_2624c|M.abscessus_ATCC_199 LFLCAVVLGGQGNKLGVVVGA--------FIIVYLPNRLLGVQVQGIDLG
MLBr_00397|M.leprae_Br4923 FAICGLTAGLGGIVLASRLGAGTPTAATGFEIDVIAAVVIGGTPLTGGLG
: :*.:. * * *. .** * * :. ::* .:*
MSMEG_3249|M.smegmatis_MC2_155 DLKYLFFGLALVVLMI--FRPQGLFPARQHLLTYGKAARDLLRATP-VKE
TH_3840|M.thermoresistible__bu DLKYLFFGLALVVMMI--FRPAGLFPARQQLLAYGRSAREMLRARPDDRE
Mflv_3572|M.gilvum_PYR-GCK NLKYLFFGLALVVLMI--FRPQGLFPARQHLLTYARAARKLLRAKPTDTE
Mvan_2843|M.vanbaalenii_PYR-1 NLKYLFFGLALVVLMI--FRPQGLFPARQHLLTYARAARKLLRAQPTDTE
MAB_2624c|M.abscessus_ATCC_199 NLKYLFFGLALVVLML--FRPQGLFPAHQKLMAYWRKTSERLSAQKPDEV
MLBr_00397|M.leprae_Br4923 RLSGTLIGAIIISMLSNGMVFMGVGNAASQIIKGIMLAAAVFVFLQRRKI
*. ::* :: :: : *: * .::: : :
MSMEG_3249|M.smegmatis_MC2_155 HTS-
TH_3840|M.thermoresistible__bu PVSS
Mflv_3572|M.gilvum_PYR-GCK PAK-
Mvan_2843|M.vanbaalenii_PYR-1 PAK-
MAB_2624c|M.abscessus_ATCC_199 EAGA
MLBr_00397|M.leprae_Br4923 GIIK