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MLESQVDQIAVVIPAHNERAHLPMSLRAMVTAAMCVPVPVQIVVVLDACTDGSEALAGDFGSDVHFVSVD AGNVGAARAAGFAYARSLRPDTVRTWYATSDADTAVPADWLVEMTTTAVEVDADMVLGGVHVPGGQDFSE SNDHVHGANMGFRADAYWSVGGFRGLKTGEDAELADRFESHGLHVHRDGDLSVETSARRSGRAPDGFADY LRELARTPVPAELGAPA
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. smegmatis MC2 155 | MSMEG_1097 | - | - | 100% (227) | glycosyl transferase, group 2 family protein |
| M. smegmatis MC2 155 | MSMEG_3859 | - | 6e-06 | 31.58% (133) | glycosyl transferase, group 2 family protein |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb2077c | ppm1 | 8e-07 | 30.83% (133) | polyprenol-monophosphomannose synthase Ppm1 |
| M. gilvum PYR-GCK | Mflv_0022 | - | 3e-70 | 57.69% (234) | glycosyl transferase family protein |
| M. tuberculosis H37Rv | Rv2051c | ppm1 | 8e-07 | 30.83% (133) | polyprenol-monophosphomannose synthase Ppm1 |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | MAB_2207 | - | 9e-07 | 30.77% (130) | polyprenol phosphate mannosyl transferase 1 |
| M. marinum M | MMAR_3028 | ppm1B | 2e-06 | 30.60% (134) | polyprenol-monophosphomannose synthase, Ppm1B |
| M. avium 104 | - | - | - | - | - |
| M. thermoresistible (build 8) | - | - | - | - | - |
| M. ulcerans Agy99 | MUL_2269 | ppm1B | 1e-06 | 30.60% (134) | C-term polyprenol-monophosphomannose synthase Ppm1B |
| M. vanbaalenii PYR-1 | Mvan_3418 | - | 4e-07 | 31.11% (135) | dolichyl-phosphate beta-D-mannosyltransferase |
CLUSTAL 2.0.9 multiple sequence alignment
MAB_2207|M.abscessus_ATCC_1997 --------------------------------------------------
Mvan_3418|M.vanbaalenii_PYR-1 --------------------------------------------------
Mb2077c|M.bovis_AF2122/97 MKLGAWVAAQLPTTRTAVRTRLTRLVVSIVAGLLLYASFPPRNCWWAAVV
Rv2051c|M.tuberculosis_H37Rv MKLGAWVAAQLPTTRTAVRTRLTRLVVSIVAGLLLYASFPPRNCWWAAVV
MMAR_3028|M.marinum_M --------------------------------------------------
MUL_2269|M.ulcerans_Agy99 --------------------------------------------------
MSMEG_1097|M.smegmatis_MC2_155 --------------------------------------------------
Mflv_0022|M.gilvum_PYR-GCK --------------------------------------------------
MAB_2207|M.abscessus_ATCC_1997 --------------------------------------------------
Mvan_3418|M.vanbaalenii_PYR-1 --------------------------------------------------
Mb2077c|M.bovis_AF2122/97 ALALLAWVLTHRATTPVGGLGYGLLFGLVFYVSLLPWIGELVGPGPWLAL
Rv2051c|M.tuberculosis_H37Rv ALALLAWVLTHRATTPVGGLGYGLLFGLVFYVSLLPWIGELVGPGPWLAL
MMAR_3028|M.marinum_M --------------------------------------------------
MUL_2269|M.ulcerans_Agy99 --------------------------------------------------
MSMEG_1097|M.smegmatis_MC2_155 --------------------------------------------------
Mflv_0022|M.gilvum_PYR-GCK --------------------------------------------------
MAB_2207|M.abscessus_ATCC_1997 --------------------------------------------------
Mvan_3418|M.vanbaalenii_PYR-1 --------------------------------------------------
Mb2077c|M.bovis_AF2122/97 ATTCALFPGIFGLFAVVVRLLPGWPIWFAVGWAAQEWLKSILPFGGFPWG
Rv2051c|M.tuberculosis_H37Rv ATTCALFPGIFGLFAVVVRLLPGWPIWFAVGWAAQEWLKSILPFGGFPWG
MMAR_3028|M.marinum_M --------------------------------------------------
MUL_2269|M.ulcerans_Agy99 --------------------------------------------------
MSMEG_1097|M.smegmatis_MC2_155 --------------------------------------------------
Mflv_0022|M.gilvum_PYR-GCK --------------------------------------------------
MAB_2207|M.abscessus_ATCC_1997 --------------------------------------------------
Mvan_3418|M.vanbaalenii_PYR-1 --------------------------------------------------
Mb2077c|M.bovis_AF2122/97 SVAFGQAEGPLLPLVQLGGVALLSTGVALVGCGLTAIALEIEKWWRTGGQ
Rv2051c|M.tuberculosis_H37Rv SVAFGQAEGPLLPLVQLGGVALLSTGVALVGCGLTAIALEIEKWWRTGGQ
MMAR_3028|M.marinum_M --------------------------------------------------
MUL_2269|M.ulcerans_Agy99 --------------------------------------------------
MSMEG_1097|M.smegmatis_MC2_155 --------------------------------------------------
Mflv_0022|M.gilvum_PYR-GCK --------------------------------------------------
MAB_2207|M.abscessus_ATCC_1997 --------------------------------------------------
Mvan_3418|M.vanbaalenii_PYR-1 --------------------------------------------------
Mb2077c|M.bovis_AF2122/97 GDAPPAVVLPAACICLVLFAAIVVWPQVRHAGSGSGGEPTVTVAVVQGNV
Rv2051c|M.tuberculosis_H37Rv GDAPPAVVLPAACICLVLFAAIVVWPQVRHAGSGSGGEPTVTVAVVQGNV
MMAR_3028|M.marinum_M --------------------------------------------------
MUL_2269|M.ulcerans_Agy99 --------------------------------------------------
MSMEG_1097|M.smegmatis_MC2_155 --------------------------------------------------
Mflv_0022|M.gilvum_PYR-GCK --------------------------------------------------
MAB_2207|M.abscessus_ATCC_1997 --------------------------------------------------
Mvan_3418|M.vanbaalenii_PYR-1 --------------------------------------------------
Mb2077c|M.bovis_AF2122/97 PRLGLDFNAQRRAVLDNHVEETLRLAADVHAGLAQQPQFVIWPENSSDID
Rv2051c|M.tuberculosis_H37Rv PRLGLDFNAQRRAVLDNHVEETLRLAADVHAGLAQQPQFVIWPENSSDID
MMAR_3028|M.marinum_M --------------------------------------------------
MUL_2269|M.ulcerans_Agy99 --------------------------------------------------
MSMEG_1097|M.smegmatis_MC2_155 --------------------------------------------------
Mflv_0022|M.gilvum_PYR-GCK --------------------------------------------------
MAB_2207|M.abscessus_ATCC_1997 --------------------------------------------------
Mvan_3418|M.vanbaalenii_PYR-1 --------------------------------------------------
Mb2077c|M.bovis_AF2122/97 PFVNPDAGQRISAAAEAIGAPILIGTLMDVPGRPRENPEWTNTAIVWNPG
Rv2051c|M.tuberculosis_H37Rv PFVNPDAGQRISAAAEAIGAPILIGTLMDVPGRPRENPEWTNTAIVWNPG
MMAR_3028|M.marinum_M --------------------------------------------------
MUL_2269|M.ulcerans_Agy99 --------------------------------------------------
MSMEG_1097|M.smegmatis_MC2_155 --------------------------------------------------
Mflv_0022|M.gilvum_PYR-GCK --------------------------------------------------
MAB_2207|M.abscessus_ATCC_1997 --------------------------------------------------
Mvan_3418|M.vanbaalenii_PYR-1 --------------------------------------------------
Mb2077c|M.bovis_AF2122/97 TGPADRHDKAIVQPFGEYLPMPWLFRHLSGYADRAGHFVPGNGTGVVRIA
Rv2051c|M.tuberculosis_H37Rv TGPADRHDKAIVQPFGEYLPMPWLFRHLSGYADRAGHFVPGNGTGVVRIA
MMAR_3028|M.marinum_M --------------------------------------------------
MUL_2269|M.ulcerans_Agy99 --------------------------------------------------
MSMEG_1097|M.smegmatis_MC2_155 --------------------------------------------------
Mflv_0022|M.gilvum_PYR-GCK --------------------------------------------------
MAB_2207|M.abscessus_ATCC_1997 --------------------------------------------------
Mvan_3418|M.vanbaalenii_PYR-1 --------------------------------------------------
Mb2077c|M.bovis_AF2122/97 GVPVGVATCWEVIFDRAPRKSILGGAQLLTVPSNNATFNKTMSEQQLAFA
Rv2051c|M.tuberculosis_H37Rv GVPVGVATCWEVIFDRAPRKSILGGAQLLTVPSNNATFNKTMSEQQLAFA
MMAR_3028|M.marinum_M --------------------------------------------------
MUL_2269|M.ulcerans_Agy99 --------------------------------------------------
MSMEG_1097|M.smegmatis_MC2_155 --------------------------------------------------
Mflv_0022|M.gilvum_PYR-GCK --------------------------------------------------
MAB_2207|M.abscessus_ATCC_1997 --------------------------------------------------
Mvan_3418|M.vanbaalenii_PYR-1 --------------------------------------------------
Mb2077c|M.bovis_AF2122/97 KVRAVEHDRYVVVAGTTGISAVIAPDGGELIRTDFFQPAYLDSQVRLKTR
Rv2051c|M.tuberculosis_H37Rv KVRAVEHDRYVVVAGTTGISAVIAPDGGELIRTDFFQPAYLDSQVRLKTR
MMAR_3028|M.marinum_M --------------------------------------------------
MUL_2269|M.ulcerans_Agy99 --------------------------------------------------
MSMEG_1097|M.smegmatis_MC2_155 --------------------------------------------------
Mflv_0022|M.gilvum_PYR-GCK --------------------------------------------------
MAB_2207|M.abscessus_ATCC_1997 --------------------------------------------------
Mvan_3418|M.vanbaalenii_PYR-1 --------------------------------------------------
Mb2077c|M.bovis_AF2122/97 LTPATRWGPILQWILVGAAAAVVLVAMRQNGWFPRPRRSEPKGENDDSDA
Rv2051c|M.tuberculosis_H37Rv LTPATRWGPILQWILVGAAAAVVLVAMRQNGWFPRPRRSEPKGENDDSDA
MMAR_3028|M.marinum_M --------------------------------------------------
MUL_2269|M.ulcerans_Agy99 --------------------------------------------------
MSMEG_1097|M.smegmatis_MC2_155 --------------------------------------------------
Mflv_0022|M.gilvum_PYR-GCK --------------------------------------------------
MAB_2207|M.abscessus_ATCC_1997 -------------------------------------------MDP---V
Mvan_3418|M.vanbaalenii_PYR-1 -------------------------------------------MSVPGGM
Mb2077c|M.bovis_AF2122/97 PPGRSEASGPPALSESDDELIQPEQGGRHSSGFGRHRATSRSYMTT--GQ
Rv2051c|M.tuberculosis_H37Rv PPGRSEASGPPALSESDDELIQPEQGGRHSSGFGRHRATSRSYMTT--GQ
MMAR_3028|M.marinum_M -------------------------------------------MTT--GQ
MUL_2269|M.ulcerans_Agy99 -------------------------------------------MTT--GQ
MSMEG_1097|M.smegmatis_MC2_155 --------------------------------------------------
Mflv_0022|M.gilvum_PYR-GCK --------------------------------------------------
MAB_2207|M.abscessus_ATCC_1997 TE------RPSARTLVIIPTYNERENLPLILGRLHKAQPDVHVLIVDDGS
Mvan_3418|M.vanbaalenii_PYR-1 TDGPGPGTRPSDRTLVIIPTYNERQNLPLIVGRVHQARPDVDILIVDDDS
Mb2077c|M.bovis_AF2122/97 PAPPAPGNRPSQRVLVIIPTFNERENLPVIHRRLTQACPAVHVLVVDDSS
Rv2051c|M.tuberculosis_H37Rv PAPPAPGNRPSQRVLVIIPTFNERENLPVIHRRLTQACPAVHVLVVDDSS
MMAR_3028|M.marinum_M PAPQSPGPRPSERTLVIIPTYNERENLPLIHRRVVDACPHVHVLIVDDNS
MUL_2269|M.ulcerans_Agy99 PAPQSPGPRPSERTLVIIPTYNERENLPLIHRRVVDACPHVHVLIVDDNS
MSMEG_1097|M.smegmatis_MC2_155 -----MLESQVDQIAVVIPAHNERAHLPMSLRAMVTAAMCVPVPVQIVVV
Mflv_0022|M.gilvum_PYR-GCK ----------MSRAVVVVPAHNEKDHLPDCLRALTTAALCVPIPVGIVVV
: *::*:.**: :** : * * : :
MAB_2207|M.abscessus_ATCC_1997 PDGTGELADEAALADPDRVHVMHRKEKGGLGAAYIAGFGWGLAR------
Mvan_3418|M.vanbaalenii_PYR-1 PDGTGQLADELSVADPDRIHVMHRTAKEGLGAAYLAGFAWGLGR------
Mb2077c|M.bovis_AF2122/97 PDGTGQLADELAQADPGRTHVMHRTAKNGLGAAYLAGFAWGLSR------
Rv2051c|M.tuberculosis_H37Rv PDGTGQLADELAQADPGRTHVMHRTAKNGLGAAYLAGFAWGLSR------
MMAR_3028|M.marinum_M PDGTGRLADELVAADPDRIHVLHRTAKNGLGAAYLEGFAWGLSR------
MUL_2269|M.ulcerans_Agy99 PDGTGRLADELVAADPDRIHVLHRTAKNGLGAAYLEGFAWGLSR------
MSMEG_1097|M.smegmatis_MC2_155 LDACTDGSEALAGDFGSDVHFVSVDAGN-VGAARAAGFAYARSLRPDT--
Mflv_0022|M.gilvum_PYR-GCK LDSCDDGSDALAGQFGADVHFVSVDAGN-VGATRAAGFEYARTLSGDDEI
*. :: *.: :**: ** :.
MAB_2207|M.abscessus_ATCC_1997 QYSVLVEMDADGSHAPEQLSRLLD-AVDAGADLAIGSRYVPGGTVVNWPW
Mvan_3418|M.vanbaalenii_PYR-1 QYTVLVEMDADGSHPPEQLARLLD-AVDAGADVVIGSRYVSGGEVVNWPR
Mb2077c|M.bovis_AF2122/97 EYSVLVEMDADGSHAPEQLQRLLD-AVDAGADLAIGSRYVAGGTVRNWPW
Rv2051c|M.tuberculosis_H37Rv EYSVLVEMDADGSHAPEQLQRLLD-AVDAGADLAIGSRYVAGGTVRNWPW
MMAR_3028|M.marinum_M GYSVLVEMDADGSHAPEQLHRLLD-AVDAGADLSIGSRYVPGGTVRNWPW
MUL_2269|M.ulcerans_Agy99 GYSVLVEMDADGSHAPEQLHRLLD-AVDAGADLSIGSRYVPGGTVRNWPW
MSMEG_1097|M.smegmatis_MC2_155 VRTWYATSDADTAVPADWLVEMTTTAVEVDADMVLGGVHVPGGQDFS---
Mflv_0022|M.gilvum_PYR-GCK GRTWYATTDADSTVDADWLVRMLG----AGADMVLGVVRVSNWRHFSPAV
: . *** : .: * .: ..**: :* *.. .
MAB_2207|M.abscessus_ATCC_1997 RRLVLSRSANVYARLVLGVKPHDITAGYRAYRREVLEKLDLGAVESHGYC
Mvan_3418|M.vanbaalenii_PYR-1 RRLVLSRTANGYSRILLGVDIHDITAGYRAYRREVLEKIDLAAVDTKGYG
Mb2077c|M.bovis_AF2122/97 RRLVLSKTANTYSRLALGIGIHDITAGYRAYRREALEAIDLDGVDSKGYC
Rv2051c|M.tuberculosis_H37Rv RRLVLSKTANTYSRLALGIGIHDITAGYRAYRREALEAIDLDGVDSKGYC
MMAR_3028|M.marinum_M RRLALSKTANTYSRLALGIGVHDITAGYRAYRREVLEKIDLASVDSKGYC
MUL_2269|M.ulcerans_Agy99 QRLALSKTANTYSRLALGIGVHDITAGYRAYRREVLEKIDLASVDSKGYC
MSMEG_1097|M.smegmatis_MC2_155 ---------------ESNDHVHGANMGFRADA-----YWSVGGFRGLKTG
Mflv_0022|M.gilvum_PYR-GCK ARRYLRGYR---SRGTGHRHIHGANMGFRAES-----YWRVGGFRALKSS
*. . *:** : ..
MAB_2207|M.abscessus_ATCC_1997 FQIDLTLRTIAHGFEVAEVPITFTERAIGESKMSGSIINEALVKVTKWGV
Mvan_3418|M.vanbaalenii_PYR-1 FQVDLTWRSINAGFTVIEVPITFTEREHGVSKMDGSTIREAIIKVAQWGL
Mb2077c|M.bovis_AF2122/97 FQIDLTWRTVSNGFVVTEVPITFTERELGVSKMSGSNIREALVKVARWGI
Rv2051c|M.tuberculosis_H37Rv FQIDLTWRTVSNGFVVTEVPITFTERELGVSKMSGSNIREALVKVARWGI
MMAR_3028|M.marinum_M FQIEMTWRSVNSGFVVVEVPITFTEREIGVSKMSGSNIREALFKVTRWGV
MUL_2269|M.ulcerans_Agy99 FQIEMTWRSVNSGFVVVEVPITFTEREIGVSKMSGSNIREALFKVTRWGV
MSMEG_1097|M.smegmatis_MC2_155 EDAELADRFESHGLHVHRDGDLSVETSARRSGRAPDGFADYLRELARTPV
Mflv_0022|M.gilvum_PYR-GCK EDVDLVRRFEDAGMFIHRDRRLSVATSDRREGRAPGGFAQHLRNLSRSDD
: ::. * *: : . . . . : : : ::::
MAB_2207|M.abscessus_ATCC_1997 QSRLDRAR-------------GVNR--------
Mvan_3418|M.vanbaalenii_PYR-1 RARLDRAR-------------GTTR--------
Mb2077c|M.bovis_AF2122/97 EGRLSRSDHARARPDIARPGAGGSRVSRADVTE
Rv2051c|M.tuberculosis_H37Rv EGRLSRSDHARARPDIARPGAGGSRVSRADVTE
MMAR_3028|M.marinum_M KGRFAGSE------------GGGDRAHTHDHS-
MUL_2269|M.ulcerans_Agy99 KGRFAGSE------------GGGDRAHTHDHS-
MSMEG_1097|M.smegmatis_MC2_155 PAELGAPA-------------------------
Mflv_0022|M.gilvum_PYR-GCK PGKADVA--------------------------
.. .