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M. bovis AF2122 / 97 Mb2077c (ppm1)

annotation: polyprenol-monophosphomannose synthase Ppm1
coordinates: 2292044 - 2294668
length: 874

VKLGAWVAAQLPTTRTAVRTRLTRLVVSIVAGLLLYASFPPRNCWWAAVVALALLAWVLTHRATTPVGGL
GYGLLFGLVFYVSLLPWIGELVGPGPWLALATTCALFPGIFGLFAVVVRLLPGWPIWFAVGWAAQEWLKS
ILPFGGFPWGSVAFGQAEGPLLPLVQLGGVALLSTGVALVGCGLTAIALEIEKWWRTGGQGDAPPAVVLP
AACICLVLFAAIVVWPQVRHAGSGSGGEPTVTVAVVQGNVPRLGLDFNAQRRAVLDNHVEETLRLAADVH
AGLAQQPQFVIWPENSSDIDPFVNPDAGQRISAAAEAIGAPILIGTLMDVPGRPRENPEWTNTAIVWNPG
TGPADRHDKAIVQPFGEYLPMPWLFRHLSGYADRAGHFVPGNGTGVVRIAGVPVGVATCWEVIFDRAPRK
SILGGAQLLTVPSNNATFNKTMSEQQLAFAKVRAVEHDRYVVVAGTTGISAVIAPDGGELIRTDFFQPAY
LDSQVRLKTRLTPATRWGPILQWILVGAAAAVVLVAMRQNGWFPRPRRSEPKGENDDSDAPPGRSEASGP
PALSESDDELIQPEQGGRHSSGFGRHRATSRSYMTTGQPAPPAPGNRPSQRVLVIIPTFNERENLPVIHR
RLTQACPAVHVLVVDDSSPDGTGQLADELAQADPGRTHVMHRTAKNGLGAAYLAGFAWGLSREYSVLVEM
DADGSHAPEQLQRLLDAVDAGADLAIGSRYVAGGTVRNWPWRRLVLSKTANTYSRLALGIGIHDITAGYR
AYRREALEAIDLDGVDSKGYCFQIDLTWRTVSNGFVVTEVPITFTERELGVSKMSGSNIREALVKVARWG
IEGRLSRSDHARARPDIARPGAGGSRVSRADVTE
Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97Mb2077cppm1-100% (874)polyprenol-monophosphomannose synthase Ppm1
M. bovis AF2122 / 97Mb2285c-2e-2028.08% (527) hypothetical protein Mb2285c
M. bovis AF2122 / 97Mb0553-6e-1632.74% (223) dolichyl-phosphate sugar synthase

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. gilvum PYR-GCKMflv_3117-0.062.80% (535) apolipoprotein N-acyltransferase
M. tuberculosis H37RvRv2051cppm10.0100.00% (874) polyprenol-monophosphomannose synthase Ppm1
M. leprae Br4923MLBr_01441-0.073.78% (534) putative apolipoprotein N-acyltransferase
M. abscessus ATCC 19977MAB_2206-1e-18058.21% (548) polyprenol-phosphate-mannose synthase 2
M. marinum MMMAR_3029ppm1A0.074.21% (605) polyprenol-monophosphomannose synthase, Ppm1A
M. avium 104MAV_4605-2e-1834.10% (217) glycosyltransferase
M. smegmatis MC2 155MSMEG_3860-0.062.52% (539) polyprenol-monophosphomannose synthase Ppm1
M. thermoresistible (build 8)TH_0732-0.061.02% (549) Polyprenol-monophosphomannose synthase Ppm1
M. ulcerans Agy99MUL_5127ppm1A0.074.05% (605) N-term polyprenol-monophosphomannose synthase Ppm1A
M. vanbaalenii PYR-1Mvan_3419-0.063.18% (535) apolipoprotein N-acyltransferase

CLUSTAL 2.0.9 multiple sequence alignment


Mb2077c|M.bovis_AF2122/97           --------------------------------------------------
Rv2051c|M.tuberculosis_H37Rv        --------------------------------------------------
Mflv_3117|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_3419|M.vanbaalenii_PYR-1       --------------------------------------------------
TH_0732|M.thermoresistible__bu      ------MADRGRRDRRAPGRRSGPTSGPTSGPTSGPASGPTRSEPPTDPI
MSMEG_3860|M.smegmatis_MC2_155      ------MADDRARRFDRFRVRPEEITEVIPAVTD----------------
MAB_2206|M.abscessus_ATCC_1997      ------MADETVEES-VAETRGDEVADLG---------------------
MMAR_3029|M.marinum_M               MARDWLGRERLPVDAQEDNPEVVQPEPGVDQTGPLGDEREPDADTADPGD
MUL_5127|M.ulcerans_Agy99           --------------------------------------------------
MLBr_01441|M.leprae_Br4923          --------------------------------------------------
MAV_4605|M.avium_104                --------------------------------------------------
                                                                                      

Mb2077c|M.bovis_AF2122/97           ----------------------------MKLGAWVAAQLP----------
Rv2051c|M.tuberculosis_H37Rv        ----------------------------MKLGAWVAAQLP----------
Mflv_3117|M.gilvum_PYR-GCK          --------------------------MGETAADADAPERPTRAR------
Mvan_3419|M.vanbaalenii_PYR-1       -----------------------------------MADTPGRVT------
TH_0732|M.thermoresistible__bu      GFDPITDDPAEDPAEDPAEDPAGDDPVEDPATDEPATDEPSRADTAEPGD
MSMEG_3860|M.smegmatis_MC2_155      ------DDPLEDPLDDDVAP--GLDDAEPEPEPRDEHDEPSRPATG---S
MAB_2206|M.abscessus_ATCC_1997      ------GERTEDSIAD---------EPEAPAETGPSRGKLFAAAVG----
MMAR_3029|M.marinum_M               DAAIADDLAEEQDEAQDEAQDSETEAETTQVSAGPSAAVRLGTAARQGLV
MUL_5127|M.ulcerans_Agy99           -------------------------------------------------M
MLBr_01441|M.leprae_Br4923          ---MVDEIIEIDPVDDDPVNG------AFATLAVPSRVVKLRATVCHALA
MAV_4605|M.avium_104                --------------------------------------------------
                                                                                      

Mb2077c|M.bovis_AF2122/97           -----------TTRTAVRTRLTRLVVSIVAGLLLYASFPPRNCWWAAVVA
Rv2051c|M.tuberculosis_H37Rv        -----------TTRTAVRTRLTRLVVSIVAGLLLYASFPPRNCWWAAVVA
Mflv_3117|M.gilvum_PYR-GCK          -----------RFGQAVVDRLPRLTAAIVAGLALCVSFPPFGWWYIAILA
Mvan_3419|M.vanbaalenii_PYR-1       -----------RLVRAVADRWHVLSLTIAAGLLLCASFPPIGWWFTAILA
TH_0732|M.thermoresistible__bu      RPADRLIRFAHRAGRAVLDRLPQLGLTVLAGLLLCVSFPPMGWWYLAPVA
MSMEG_3860|M.smegmatis_MC2_155      RIGGWVARRGSRFGKGVLDRCAPLSAAIGGGLALWLSFPPIGWWFTAFPG
MAB_2206|M.abscessus_ATCC_1997      -------ARIVAFGRAWMRTATRQGAALIAGLALCASFPPWGFWWAAFPA
MMAR_3029|M.marinum_M               AFGAGAAARLPGLWAATRPRLVRLVVSLVAGFLMYASFPPTNWWWAAIVS
MUL_5127|M.ulcerans_Agy99           AFGAGAAARLPGLWAATRPRLVRLVVSLVAGFLMYASFPPTNWWWAAIVS
MLBr_01441|M.leprae_Br4923          QMGVATVARVPATWAMLVPRLPRLVVAVVAGLLFCASFPSLNWWWAAVVA
MAV_4605|M.avium_104                --------------------------------------------------
                                                                                      

Mb2077c|M.bovis_AF2122/97           LALLAWVLTHRATTPVGGLGYGLLFGLVFYVSLLPWIGELVGPGPWLALA
Rv2051c|M.tuberculosis_H37Rv        LALLAWVLTHRATTPVGGLGYGLLFGLVFYVSLLPWIGELVGPGPWLALA
Mflv_3117|M.gilvum_PYR-GCK          FAVLGWVLTRERTTVAGGAGYGLLFGLAFYVPLLPWISGLVGAVPWLALS
Mvan_3419|M.vanbaalenii_PYR-1       FAVFGWVLTRNSTTVAGGAGYGLLFGVAFYVPLLPWISGLVGAVPWLALS
TH_0732|M.thermoresistible__bu      LALLGGVLVHRATTLAGGFGYGVLFGLAFHIPLLPWISGLVGAVPWLALS
MSMEG_3860|M.smegmatis_MC2_155      LALLGWVLTRTATTKAGGFGYGVLFGLAFYVPLLPWISGLVGAVPWLALA
MAB_2206|M.abscessus_ATCC_1997      LSVLGLVLWSPRTTLRGGLGYGLLFGLAFFIPLLPWTGQLVGAVPWLALS
MMAR_3029|M.marinum_M               VALLTWVLMHPTTTPVGGLGYGFVFGLACFVPLLPWIGTLVGPVPWLVLA
MUL_5127|M.ulcerans_Agy99           VALLTWVLMHPASTPVGGLGYGFVFGLACFVPLLPWIGTLVGPVPWLVLA
MLBr_01441|M.leprae_Br4923          FALLAWVLTHPTTTPVGGLGYGFLFGLAFYLPLLSWISSLVGATPWWALA
MAV_4605|M.avium_104                --------------MPGADGR-----VTVVLPCLNEEESLPG--------
                                                    *. *      :.  :. *     * *        

Mb2077c|M.bovis_AF2122/97           TTCALFPGIFGLFAVVVRLLPGWPIWFAVGWAAQEWLKSILPFGGFPWGS
Rv2051c|M.tuberculosis_H37Rv        TTCALFPGIFGLFAVVVRLLPGWPIWFAVGWAAQEWLKSILPFGGFPWGS
Mflv_3117|M.gilvum_PYR-GCK          VVEALFCALFGMLAVVVRRLPGWPLWFAGLWSAQEWLKSTVPFGGFPWGV
Mvan_3419|M.vanbaalenii_PYR-1       FAEALFPALFGMAAVAIRRLPGWPLWFAGLWSAQEWLKSAVPFGGFPWGT
TH_0732|M.thermoresistible__bu      VVQAVFPGLFGLAAVAVRRLPGRPVWFALLWVAYEWIKSSVPFGGFPWGV
MSMEG_3860|M.smegmatis_MC2_155      FAESLFCGLFGLGAVVVVRLPGWPLWFATLWVAAEWAKSTFPFGGFPWGA
MAB_2206|M.abscessus_ATCC_1997      LLCALWVALFGLLAVAVRNLPGWPLWFAAAWSATEWGKASIPFGGFPWGR
MMAR_3029|M.marinum_M               TTSALFPGLFGLSAVVVRRLPGWPIWFAVLWGAQEWLKSIVPFGGFPWGS
MUL_5127|M.ulcerans_Agy99           TTSALFPGLFGLSAVVVRRLPGWPIWFAVLWGAQEWLKSIVPFGGFPWGS
MLBr_01441|M.leprae_Br4923          TAAAFLPGFFGLLAVVVGPLPGWPIWFAVVWAAQEWLKSVVPFGGFPWGS
MAV_4605|M.avium_104                --------------VLATIPPGYRALVVDNNSTDDTAGVARRHG------
                                                  *     **    ..    : :       .*      

Mb2077c|M.bovis_AF2122/97           VAFGQAEGPLLPLVQLGGVALLSTGVALVGCGLTAIALEIEKWWRT----
Rv2051c|M.tuberculosis_H37Rv        VAFGQAEGPLLPLVQLGGVALLSTGVALVGCGLTAIALEIEKWWRT----
Mflv_3117|M.gilvum_PYR-GCK          VGFSQSESPLLPLAYVGGAPLVSFALVLLAFSLGALVLGVADWWRR----
Mvan_3419|M.vanbaalenii_PYR-1       VAFSQTESPLLPLAYVGGAPLVSFAVVLLAFSLAALVFAVADWWRR----
TH_0732|M.thermoresistible__bu      VAYSQTNGPLLALAQIGGAPLVSFAVALTGFSLAALTAAIVRWWRS----
MSMEG_3860|M.smegmatis_MC2_155      SSYGQTNGPLLALARIGGAPLVSFAVALIGFSLTLLTAQIVWWWR-----
MAB_2206|M.abscessus_ATCC_1997      VAFGQGDSPMLGLARYGGAPLVSFAVALGAFAVTALGIEMYRWWRS----
MMAR_3029|M.marinum_M               VAFGQVDGPLLPLAQLGGVPLLSTGVVLVGSSFAAIALEIEKWWRTGSPA
MUL_5127|M.ulcerans_Agy99           VAFGQVDGPLLPLAQLGGVPLLSTGVALVGSSFAAIALEIEKWWRTGSPA
MLBr_01441|M.leprae_Br4923          VAFGQADGPLLPLAQLGGAPLLSMAIVLVGCSTTAIALEVVKWWRS----
MAV_4605|M.avium_104                -------AQVVTETRAG---------------------------------
                                           . ::  .  *                                 

Mb2077c|M.bovis_AF2122/97           -------GGQG---DAPPAVVLPAACICLVLFAAIVVWPQVRHAGSGSGG
Rv2051c|M.tuberculosis_H37Rv        -------GGQG---DAPPAVVLPAACICLVLFAAIVVWPQVRHAGSGSGG
Mflv_3117|M.gilvum_PYR-GCK          ------DAATR--AATPPAVVLPGLCIAVVVLASTLAWPHVRKAGLGAGD
Mvan_3419|M.vanbaalenii_PYR-1       ------DATAR--AAAPPAVVLPGLCITLVLLAATLAWPNVRKSGLGAGD
TH_0732|M.thermoresistible__bu      ------DSHR----AAPPAVVLPGLCIAAVLLATAVVWPQVRYSGAGADA
MSMEG_3860|M.smegmatis_MC2_155      ------HGHKP--GVPAPAVMLPGVAIAASLLVTALVWPQVRQSGTGAGD
MAB_2206|M.abscessus_ATCC_1997      ------PSVGPDGARPMPSVLLPGVCVCLVLFAMAISWQQVRHASHGATD
MMAR_3029|M.marinum_M               APQADPEAAQPVEPAKPPAVLLPGITVCLVLFAAVIVWPQVRHAGAGSGG
MUL_5127|M.ulcerans_Agy99           APQADPEAAQPVEPAKPPAVLLPGITVCLVLFAAVIVWPQVRHAGAGSGG
MLBr_01441|M.leprae_Br4923          -------SGQSNRSDPPPAVVLPGVCVCLVLLAVVVVWPQVRHAGAGSGG
MAV_4605|M.avium_104                ----------------------YGAAVHAGVLAATTPIVAVLDADGSMDG
                                                           .  :   ::.       *  :. .   

Mb2077c|M.bovis_AF2122/97           -EPTVTVAVVQGNVPRLGLDFNAQRRAVLDNHVEETLRLAADVHAGLAQQ
Rv2051c|M.tuberculosis_H37Rv        -EPTVTVAVVQGNVPRLGLDFNAQRRAVLDNHVEETLRLAADVHAGLAQQ
Mflv_3117|M.gilvum_PYR-GCK          -EPPVTVAAVQGNVPRLGLEFNAQRRAVLDNHVRETLRLADDVRAGRVPQ
Mvan_3419|M.vanbaalenii_PYR-1       -EPPVTVAAVQGNVPRLGLDFNAQRRAVLDNHVRETLRLAEDVRAGRAPQ
TH_0732|M.thermoresistible__bu      ADQPIRVAAVQGNVPRLGLDFNAQRRAVLDNHVRETMRLAEDVRAGRAEQ
MSMEG_3860|M.smegmatis_MC2_155      -DTAVTVAAVQGNVPRLGLEFNAQRRAVLDNHVKETLRLADDVKAGRAAQ
MAB_2206|M.abscessus_ATCC_1997      -GRTVTVAAVQGNVPRLGLDFNAQRRAVLDYHVKETVLLAQDVKAGKAPA
MMAR_3029|M.marinum_M               -EPTITVAVVQGNVPRLGLDFNAQRRAVLDNHVRETLELAEDVRAGLAPQ
MUL_5127|M.ulcerans_Agy99           -EPTITVAVVQGNVPRLGLDFNAQRRAVLDNHVRETLELAEDVRADLAPQ
MLBr_01441|M.leprae_Br4923          -EPVITVAAVQGNVPRLGLDFNAQRRAVLDNHVHETLRLAEDVRAGIVPQ
MAV_4605|M.avium_104                -----------ADLPRLVAALEAG----------------ADLVTGRRRP
                                               .::***   ::*                  *: :.    

Mb2077c|M.bovis_AF2122/97           PQFVIWPENSSDIDPFVNPDAGQRISAAAEAIGAPILIGTLMDVPGRPR-
Rv2051c|M.tuberculosis_H37Rv        PQFVIWPENSSDIDPFVNPDAGQRISAAAEAIGAPILIGTLMDVPGRPR-
Mflv_3117|M.gilvum_PYR-GCK          PMLVVWPENSSDIDPIANPDAAQEISRAAAAIDAPVLVGGVVAAPGYSR-
Mvan_3419|M.vanbaalenii_PYR-1       PMLVVWPENSSDIDPLANADASREISTAADAINAPILVGGVVAAPGYSR-
TH_0732|M.thermoresistible__bu      PLFVVWPENSSDIDPLANPDAHQQISAAAAAIRAPILVGGVVRAPGYRP-
MSMEG_3860|M.smegmatis_MC2_155      PMFVIWPENSSDIDPLLNADASAQITTAAEAIDAPILVGGVVRADGYTP-
MAB_2206|M.abscessus_ATCC_1997      PQFVVWPENSSDIDPIRNADAAEAINEAAQAIGVPILVGGVLRHPDSTP-
MMAR_3029|M.marinum_M               PQFVIWPEDSSDIDPLINPDAAQQISKAAVAIGAPILVGTVLDAPGSSQK
MUL_5127|M.ulcerans_Agy99           PQFVIWPEDSSDIDPLINPDAAQQISKAAVAIGAPILVGTVLDAPGSSQK
MLBr_01441|M.leprae_Br4923          PQFVIWPENASDIDPLVNGDAGQEITVAAATIDAPILVGTVLDVQGPVP-
MAV_4605|M.avium_104                VRGLRWPWVAR--------------------------VG-----------
                                       : **  :                           :*           

Mb2077c|M.bovis_AF2122/97           --ENPEWTNTAIVWNPGTGPADRHDKAIVQPFGEYLPMPWLFRHLSGYAD
Rv2051c|M.tuberculosis_H37Rv        --ENPEWTNTAIVWNPGTGPADRHDKAIVQPFGEYLPMPWLFRHLSGYAD
Mflv_3117|M.gilvum_PYR-GCK          --DNPVSNNTVIVWNPETGPSDRHDKRIVQPFGEYLPWRSFFSKLSSYAD
Mvan_3419|M.vanbaalenii_PYR-1       --TNPVSNNTVIVWNPETGPGDRHDKRIVQPFGEYLPWRDFFSKLSPYAD
TH_0732|M.thermoresistible__bu      --DNPVATNSVLVWDPETGPTDRHDKQIVQPFGEYLPWRDFFRRLSPYAD
MSMEG_3860|M.smegmatis_MC2_155      --DNPVANNTVIVWEPTDGPGERHDKQIVQPFGEYLPWRGFFKHLSSYAD
MAB_2206|M.abscessus_ATCC_1997      --EQPKSINSIIVWDPNTGPGERHDKQIVQPFGEYLPWRSFFAHFSEYAD
MMAR_3029|M.marinum_M               NLENAEYTNTVLVWNPTTGPGDRHDKEIVQPFGEYLPMPWLFRHLSGYAD
MUL_5127|M.ulcerans_Agy99           NLENAEYTNTVLVWNPTTGPGDRHDKEIVQPFGEYLPMPWLFRHLSGYAD
MLBr_01441|M.leprae_Br4923          --QAPEYTNTVIVWNPGTGPADRHDKEIVQPFGEYLPMPWLFKRLSKYAD
MAV_4605|M.avium_104                --------TVVMSWRLRTRHG--------LPVHDIAPMR-----------
                                            .  : *                *. :  *             

Mb2077c|M.bovis_AF2122/97           RAGHFVPGNG--TGVVRIAGVPVGVATCWEVIFDRAPRKSILGGAQLLTV
Rv2051c|M.tuberculosis_H37Rv        RAGHFVPGNG--TGVVRIAGVPVGVATCWEVIFDRAPRKSILGGAQLLTV
Mflv_3117|M.gilvum_PYR-GCK          RAGYFVPGDG--DGVVEAAGIPVGITTCWEVIFDRAARESVRNGAQLLAV
Mvan_3419|M.vanbaalenii_PYR-1       RAGYFVPGDG--DGVVQAAGVPVGITTCWEVIFDRAARQSVLSGAQFLAV
TH_0732|M.thermoresistible__bu      RAGYFIPVDG--DGVVTAAGVPVGVTTCWEVIFDRAARESVRNGAEVLAV
MSMEG_3860|M.smegmatis_MC2_155      RAGYFVPGTG--TGVVHAAGVPIGITTCWEVIFDRAARESVLNGAQVLAV
MAB_2206|M.abscessus_ATCC_1997      RAGYFVPGDG--NGVVTAGGVNIGVATCWEVLFDRALRQSTLNGAEILAV
MMAR_3029|M.marinum_M               RAGHFVPRPG--SDVVNIAGVPVGVSTCWEVIFDRAPRKAVRNGAQLLAV
MUL_5127|M.ulcerans_Agy99           RAGHFVPRPG--SDVVNIAGVPVGVSTCWEVIFDRAPRRAVRNGAQLLAV
MLBr_01441|M.leprae_Br4923          RVSHIVPRQSQSSGVVRIAGVPIGVTTCWEVIFDRAARKAVLNGAQLLAA
MAV_4605|M.avium_104                ----------------------------------VARRDALLG----LGV
                                                                       * * :  .    * .

Mb2077c|M.bovis_AF2122/97           PSNNATFNKTMSEQQLAFAKVRAVEHDRYVVVAGTTGISAVIAPDGGELI
Rv2051c|M.tuberculosis_H37Rv        PSNNATFNKTMSEQQLAFAKVRAVEHDRYVVVAGTTGISAVIAPDGGELI
Mflv_3117|M.gilvum_PYR-GCK          PSNNATFDQAMSEQQLAFGRLRAVEHDRYVVVAGTTGISAVIAPDGHEIV
Mvan_3419|M.vanbaalenii_PYR-1       PSNNATFDQAMSEQQLAFGRLRAVEHDRFVVVSGTTGISAVIAPDGREIA
TH_0732|M.thermoresistible__bu      PTNNATFDEAMSEQHLAFARLRAVEHNRYAVVAGTTGISAVITPDGREVA
MSMEG_3860|M.smegmatis_MC2_155      PSNNATFDEAMSAQQLAFGKLRAVEHDRYVVVAGTTGISAVIAPDGHEIS
MAB_2206|M.abscessus_ATCC_1997      PSNNALFGSAMSEQQLAISKVRAVEHDREVVVVGTTGISAFVSPDGVDAG
MMAR_3029|M.marinum_M               PSNNATFNKTMSEQQLAFAKVRAVEHDRYVVVAGTTGISAVIAPDGRELV
MUL_5127|M.ulcerans_Agy99           PSNNATFNKTMSEQQLAFAKVRAVEHDRYVVVAGTTGISAVIAPDGRELV
MLBr_01441|M.leprae_Br4923          PTNNATFNKTMSEQQLAFAKVRAVEHDRYVVVTGTTGISSVIAPDGSELV
MAV_4605|M.avium_104                ADRRSGYPLELLVRAAAAG-WRVVELD--VRYGPRTGGKSKVSG------
                                    . ..: :   :  :  * .  *.** :  .     ** .: ::       

Mb2077c|M.bovis_AF2122/97           RTDFFQPAYLDSQVRLKTRLTPATRWGPILQWILVGAAAAV----VLVAM
Rv2051c|M.tuberculosis_H37Rv        RTDFFQPAYLDSQVRLKTRLTPATRWGPILQWILVGAAAAV----VLVAM
Mflv_3117|M.gilvum_PYR-GCK          RTGWFEPAYLDQQVRLKTSLTPATRFGPYVEGVLIALGVSG----VVGAI
Mvan_3419|M.vanbaalenii_PYR-1       RTGWFEPAYLDQQIRLKTRLTPATRFGPYIEAVLVAIGVSG----VLGAM
TH_0732|M.thermoresistible__bu      RTRFFEPAYLDVQVRLKTQLSPATRYGPVIHGALIAAALAGLGAALAGTV
MSMEG_3860|M.smegmatis_MC2_155      RTEWFQPAYLDNQIRLKTDLTPATKWGPIVQAVLVIAGVAV----LLIAI
MAB_2206|M.abscessus_ATCC_1997      RTTFFEPAYIDMQVRLHNDLTPATQWGPWVEWALALIAGLAVLASAGLAI
MMAR_3029|M.marinum_M               RTDFFEPAYLDIQVRLKTRLTPATRWAPILQWLMVGAAGVL----ILVAM
MUL_5127|M.ulcerans_Agy99           RTDFFEPAYLDIQVRLKTRLTPATRWAPILQWLMVGAAGVL----ILVAM
MLBr_01441|M.leprae_Br4923          RTDFFVPAYLDMQVRLKAKLTPATCWGLTLQWILVGTAGAI----VLAAM
MAV_4605|M.avium_104                --------------SLRGSITAILDFWKVIS-------------------
                                                   *:  ::.   :   :                    

Mb2077c|M.bovis_AF2122/97           RQNGWFPRPRRSEPKGEN----------------------DDSDAPPGRS
Rv2051c|M.tuberculosis_H37Rv        RQNGWFPRPRRSEPKGEN----------------------DDSDAPPGRS
Mflv_3117|M.gilvum_PYR-GCK          LHNGSFLPGRLRRRR-----------------------------------
Mvan_3419|M.vanbaalenii_PYR-1       LHNGSFVPARFRGRR-----------------------------------
TH_0732|M.thermoresistible__bu      LQNGRLVPHALRGRRRAKESHDDGPATRPRHHGQSTSESAHSGDHPDLQR
MSMEG_3860|M.smegmatis_MC2_155      LHNGRFAPRMLRRRS-----------------------------------
MAB_2206|M.abscessus_ATCC_1997      LHNGGLKRPEPEVEP-----------------------------------
MMAR_3029|M.marinum_M               RHNGWFPRPTRRRSGPAG--------------------EADQSDAPQDEA
MUL_5127|M.ulcerans_Agy99           RHNGWFPRPTRRRSGPAG--------------------EADQSDAPQDEA
MLBr_01441|M.leprae_Br4923          RHNNGSRSRIVLGLGSSASL-------------KTRVRQANVREALTLRL
MAV_4605|M.avium_104                --------------------------------------------------
                                                                                      

Mb2077c|M.bovis_AF2122/97           EASGPPALSESDDELIQPEQGGRHSSGFGRHRATSRSYMTTGQPAPPAPG
Rv2051c|M.tuberculosis_H37Rv        EASGPPALSESDDELIQPEQGGRHSSGFGRHRATSRSYMTTGQPAPPAPG
Mflv_3117|M.gilvum_PYR-GCK          ---PTSDDGEGAT-------------------------------------
Mvan_3419|M.vanbaalenii_PYR-1       ---PTTDDDEGAT-------------------------------------
TH_0732|M.thermoresistible__bu      TGQSAADRGSGASGLPRGARADRRRRQPRRHR------------------
MSMEG_3860|M.smegmatis_MC2_155      ---ATTVKR-----------------------------------------
MAB_2206|M.abscessus_ATCC_1997      ---ASPTKET----------------------------------------
MMAR_3029|M.marinum_M               DDSGAASRNESEDDLQTAT--GTPPEAGGHHST-----------------
MUL_5127|M.ulcerans_Agy99           DDSGATSRNESEDDLQTAT--GTPPEAGGHHST-----------------
MLBr_01441|M.leprae_Br4923          GDRPLIHLSRLVTTLRSIYKGGQKPRYFGRHKGAK---------------
MAV_4605|M.avium_104                --------------------------------------------------
                                                                                      

Mb2077c|M.bovis_AF2122/97           NRPSQRVLVIIPTFNERENLPVIHRRLTQACPAVHVLVVDDSSPDGTGQL
Rv2051c|M.tuberculosis_H37Rv        NRPSQRVLVIIPTFNERENLPVIHRRLTQACPAVHVLVVDDSSPDGTGQL
Mflv_3117|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_3419|M.vanbaalenii_PYR-1       --------------------------------------------------
TH_0732|M.thermoresistible__bu      --------------------------------------------------
MSMEG_3860|M.smegmatis_MC2_155      --------------------------------------------------
MAB_2206|M.abscessus_ATCC_1997      --------------------------------------------------
MMAR_3029|M.marinum_M               --------------------------------------------------
MUL_5127|M.ulcerans_Agy99           --------------------------------------------------
MLBr_01441|M.leprae_Br4923          --------------------------------------------------
MAV_4605|M.avium_104                --------------------------------------------------
                                                                                      

Mb2077c|M.bovis_AF2122/97           ADELAQADPGRTHVMHRTAKNGLGAAYLAGFAWGLSREYSVLVEMDADGS
Rv2051c|M.tuberculosis_H37Rv        ADELAQADPGRTHVMHRTAKNGLGAAYLAGFAWGLSREYSVLVEMDADGS
Mflv_3117|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_3419|M.vanbaalenii_PYR-1       --------------------------------------------------
TH_0732|M.thermoresistible__bu      --------------------------------------------------
MSMEG_3860|M.smegmatis_MC2_155      --------------------------------------------------
MAB_2206|M.abscessus_ATCC_1997      --------------------------------------------------
MMAR_3029|M.marinum_M               --------------------------------------------------
MUL_5127|M.ulcerans_Agy99           --------------------------------------------------
MLBr_01441|M.leprae_Br4923          --------------------------------------------------
MAV_4605|M.avium_104                --------------------------------------------------
                                                                                      

Mb2077c|M.bovis_AF2122/97           HAPEQLQRLLDAVDAGADLAIGSRYVAGGTVRNWPWRRLVLSKTANTYSR
Rv2051c|M.tuberculosis_H37Rv        HAPEQLQRLLDAVDAGADLAIGSRYVAGGTVRNWPWRRLVLSKTANTYSR
Mflv_3117|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_3419|M.vanbaalenii_PYR-1       --------------------------------------------------
TH_0732|M.thermoresistible__bu      --------------------------------------------------
MSMEG_3860|M.smegmatis_MC2_155      --------------------------------------------------
MAB_2206|M.abscessus_ATCC_1997      --------------------------------------------------
MMAR_3029|M.marinum_M               --------------------------------------------------
MUL_5127|M.ulcerans_Agy99           --------------------------------------------------
MLBr_01441|M.leprae_Br4923          --------------------------------------------------
MAV_4605|M.avium_104                --------------------------------------------------
                                                                                      

Mb2077c|M.bovis_AF2122/97           LALGIGIHDITAGYRAYRREALEAIDLDGVDSKGYCFQIDLTWRTVSNGF
Rv2051c|M.tuberculosis_H37Rv        LALGIGIHDITAGYRAYRREALEAIDLDGVDSKGYCFQIDLTWRTVSNGF
Mflv_3117|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_3419|M.vanbaalenii_PYR-1       --------------------------------------------------
TH_0732|M.thermoresistible__bu      --------------------------------------------------
MSMEG_3860|M.smegmatis_MC2_155      --------------------------------------------------
MAB_2206|M.abscessus_ATCC_1997      --------------------------------------------------
MMAR_3029|M.marinum_M               --------------------------------------------------
MUL_5127|M.ulcerans_Agy99           --------------------------------------------------
MLBr_01441|M.leprae_Br4923          --------------------------------------------------
MAV_4605|M.avium_104                --------------------------------------------------
                                                                                      

Mb2077c|M.bovis_AF2122/97           VVTEVPITFTERELGVSKMSGSNIREALVKVARWGIEGRLSRSDHARARP
Rv2051c|M.tuberculosis_H37Rv        VVTEVPITFTERELGVSKMSGSNIREALVKVARWGIEGRLSRSDHARARP
Mflv_3117|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_3419|M.vanbaalenii_PYR-1       --------------------------------------------------
TH_0732|M.thermoresistible__bu      --------------------------------------------------
MSMEG_3860|M.smegmatis_MC2_155      --------------------------------------------------
MAB_2206|M.abscessus_ATCC_1997      --------------------------------------------------
MMAR_3029|M.marinum_M               --------------------------------------------------
MUL_5127|M.ulcerans_Agy99           --------------------------------------------------
MLBr_01441|M.leprae_Br4923          --------------------------------------------------
MAV_4605|M.avium_104                --------------------------------------------------
                                                                                      

Mb2077c|M.bovis_AF2122/97           DIARPGAGGSRVSRADVTE
Rv2051c|M.tuberculosis_H37Rv        DIARPGAGGSRVSRADVTE
Mflv_3117|M.gilvum_PYR-GCK          -------------------
Mvan_3419|M.vanbaalenii_PYR-1       -------------------
TH_0732|M.thermoresistible__bu      -------------------
MSMEG_3860|M.smegmatis_MC2_155      -------------------
MAB_2206|M.abscessus_ATCC_1997      -------------------
MMAR_3029|M.marinum_M               -------------------
MUL_5127|M.ulcerans_Agy99           -------------------
MLBr_01441|M.leprae_Br4923          -------------------
MAV_4605|M.avium_104                -------------------