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MIAIGGVIGAGLFVGSGVVIRATGPAAFLTYALCGALIVLVMRMLGEMAAANPSTGAFADYAAKALGGWA GFSVGWLYWYFWVIVVGFEAVAGGKVLTYWIDAPLWLASLCLMMMMTATNLVSVSSFGEFEFWFAGVKVA TIVGFLVLGTAFAFGLLPGHGMDFSNLSAHGGFFPDGVGAVFAAIVVAIFSMTGTEVVTIAAAEAPDPQR AVQRAMSTVVARIVIFFVGSVFLLTVILPWNSLELGASPYVAALRHMGIGGADQIMNAVVLTAVLSCLNS GLYTASRMLFVLAARQEAPAQLVKVNRRGVPTFAIMGSSVVGFLCVIMAWVSPATVFVFLLNSSGAVILF VYLLIALSQIVLRRQTSGQNLGVRMWLFPGLSIVTVTGIVAVLARMAFDYAARSQLWLSLLSWAVVVGCY LVTTLVRRPLNRPW
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb0535 | gabP | - | 100% (434) | GABA permease GabP |
| M. bovis AF2122 / 97 | Mb2151 | ansP1 | 3e-70 | 35.19% (432) | L-asparagine permease ansP1 |
| M. bovis AF2122 / 97 | Mb1730c | cycA | 4e-68 | 36.66% (371) | D-serine/alanine/glycine transporter protein CycA |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. gilvum PYR-GCK | Mflv_1998 | - | 1e-167 | 68.57% (420) | amino acid permease-associated region |
| M. tuberculosis H37Rv | Rv0522 | gabP | 0.0 | 100.00% (434) | GABA permease GabP |
| M. leprae Br4923 | MLBr_01305 | ansP2 | 2e-71 | 36.36% (407) | putative L-asparagine permease |
| M. abscessus ATCC 19977 | MAB_4909 | - | 1e-164 | 65.67% (434) | GABA permease GabP |
| M. marinum M | MMAR_0862 | gabP | 0.0 | 79.67% (428) | GabA permease (gamma-aminobutyrate permease) GabP |
| M. avium 104 | MAV_4626 | - | 0.0 | 77.25% (422) | gaba permease |
| M. smegmatis MC2 155 | MSMEG_5473 | - | 1e-159 | 66.20% (432) | transporter |
| M. thermoresistible (build 8) | TH_0471 | - | 4e-16 | 21.22% (443) | POSSIBLE CATIONIC AMINO ACID TRANSPORT INTEGRAL MEMBRANE |
| M. ulcerans Agy99 | MUL_4508 | gabP_1 | 1e-115 | 49.06% (426) | GabA permease GabP_1 |
| M. vanbaalenii PYR-1 | Mvan_3196 | - | 6e-19 | 25.06% (395) | ethanolamine transproter |
CLUSTAL 2.0.9 multiple sequence alignment
Mflv_1998|M.gilvum_PYR-GCK --------------MSAAPT-----LKKALNQRQLTMIAIG----GVIGA
MSMEG_5473|M.smegmatis_MC2_155 --------------MGDTPA-----LKRALSQRQLRMIAIG----GVIGA
MAB_4909|M.abscessus_ATCC_1997 --------------MATTAAPSEGGLQHSLQKRHLTMIAIG----GVIGA
Mb0535|M.bovis_AF2122/97 ------------------------------------MIAIG----GVIGA
Rv0522|M.tuberculosis_H37Rv ------------------------------------MIAIG----GVIGA
MMAR_0862|M.marinum_M ------------------------------------MIAIG----GVIGA
MAV_4626|M.avium_104 --------------MAGTSQ-----LRQGLSQRQLSMIALG----GVIGA
MUL_4508|M.ulcerans_Agy99 --------------MAGADTEHEIALGKGLRQRHLSLIALG----GVIGA
MLBr_01305|M.leprae_Br4923 MATLAESPEPKSGASRAGVLGEEAGYHKGLKPRQLQMIGIG----GAIGT
TH_0471|M.thermoresistible__bu --MTDRLRVKSVEQSIADTDEPDSRLRKDLSWWDLTVFGVS----VVIGA
Mvan_3196|M.vanbaalenii_PYR-1 -MSGEAHSTHTTRGVEAHRESDAYLQKRQLKKGSAGWILLAGLGISYVVS
: :. : :
Mflv_1998|M.gilvum_PYR-GCK GLFVGSGVVIA-DTGPGAFLTYGMAGVLIIMVMRMLAEMAVANPSTGSFA
MSMEG_5473|M.smegmatis_MC2_155 GLFVGSGVVIG-DTGPGTFITYGLAGVLIIMVMRMLAEMAVANPSTGSFA
MAB_4909|M.abscessus_ATCC_1997 GLFVGSGATIQ-AAGPAAFLTYAITGVLIVLVMRMLGEMAVANPSTGSFA
Mb0535|M.bovis_AF2122/97 GLFVGSGVVIR-ATGPAAFLTYALCGALIVLVMRMLGEMAAANPSTGAFA
Rv0522|M.tuberculosis_H37Rv GLFVGSGVVIR-ATGPAAFLTYALCGALIVLVMRMLGEMAAANPSTGAFA
MMAR_0862|M.marinum_M GLFVGSGVVIR-ATGPAAFLTYALCGLLILLVMRMLAEMAAANPSTGSFA
MAV_4626|M.avium_104 GLFVGSGVVIK-DTGPAAFLTYALCGLLIVLVMRMLGEMAAANPSTGSFA
MUL_4508|M.ulcerans_Agy99 GLFVGSGVVIA-GTGPAAVISFLIAGLITMLIMRMLAEMAASQPVVGSFY
MLBr_01305|M.leprae_Br4923 GLFLGAGGRLA-KAGPGLFLVYAVCGVFVFLILRALGELVLHRPSSGSFV
TH_0471|M.thermoresistible__bu GIFTVTASTAGNITGPAISVSFIIAAIACGLAALCYAEFASTVPVAGSAY
Mvan_3196|M.vanbaalenii_PYR-1 GDYSGWNFGLGQGGFGGLAIAAVVIAAMYLAMVLGMAEMSSALPAAGGGY
* : . : : . .*: * *.
Mflv_1998|M.gilvum_PYR-GCK DYSRNALGHWAGFSVGWLYWYFWVIVVGFEAIAGAKIVQYWM--------
MSMEG_5473|M.smegmatis_MC2_155 DYSRNALGNWAGFSVGWLYWYFWVIVVGFEAIAGAKIIQFWI--------
MAB_4909|M.abscessus_ATCC_1997 DYSRRALGDWAGFSVGWLYWYFWVIVVGFEAVAGGKLIQDWLP-------
Mb0535|M.bovis_AF2122/97 DYAAKALGGWAGFSVGWLYWYFWVIVVGFEAVAGGKVLTYWI--------
Rv0522|M.tuberculosis_H37Rv DYAAKALGGWAGFSVGWLYWYFWVIVVGFEAVAGGKVLTYWI--------
MMAR_0862|M.marinum_M DFAADALGGWAGFSVGWLYWYFWVIVVGFEAVAGAKVLMYWI--------
MAV_4626|M.avium_104 DYAAAALGRWAGFSVAWLYWYFWVIVVGFEAVAGGKVLNYWF--------
MUL_4508|M.ulcerans_Agy99 VYARQALGPRGGFVTGWMYWYFFVVVVAVETVAGGRILQLWVP-------
MLBr_01305|M.leprae_Br4923 SYAREFFGEKAAYVVGWLYFLDWAMTAIVDTTAIATYLHRWTIFT-----
TH_0471|M.thermoresistible__bu TFSYATFGEFVAWIIGWDLILEFSVAAAVVAKGWSSYLGEVFEFAGATTR
Mvan_3196|M.vanbaalenii_PYR-1 TFARRALGPWGGFATGTAILIEYSIAPAAIATFIGAYVESLGLFG-----
:: :* .: . : :. : . :
Mflv_1998|M.gilvum_PYR-GCK --DVPLWLSALIFMVLMTATNLFSVASYGEFEFWFAGIKVAAIIAFIAVG
MSMEG_5473|M.smegmatis_MC2_155 --DVPLWLTALILLIAMTATNLFSVSSFGEFEYWFAGVKVAAILAFIGLG
MAB_4909|M.abscessus_ATCC_1997 --HAPLWLIALLLMLAMTATNLFSVRSYGEFEYWFASVKVAAIVAFLVAG
Mb0535|M.bovis_AF2122/97 --DAPLWLASLCLMMMMTATNLVSVSSFGEFEFWFAGVKVATIVGFLVLG
Rv0522|M.tuberculosis_H37Rv --DAPLWLASLCLMMMMTATNLVSVSSFGEFEFWFAGVKVATIVGFLVLG
MMAR_0862|M.marinum_M --HAPLWLLSLCLMIMMTATNLFSVSSFGEFEFWFAGIKVAVIVVFLALG
MAV_4626|M.avium_104 --HAPLWVLSLGLMLLMTATNLFSVSSFGEFEFWFAGIKVATIVIFLVVG
MUL_4508|M.ulcerans_Agy99 --QIPLWVLSLGLLLALTATNLVSARSFGEFEYWFSSIKVIAVVVFLGLG
MLBr_01305|M.leprae_Br4923 --ALPQWTLALLALAVVLVMNLISVEWFGELEFWAALIKVCALMAFLVVG
TH_0471|M.thermoresistible__bu LGPITLDWGALLIIGFVTVLLATGTKLSANVSLAITVIKVGVVLLVVIVG
Mvan_3196|M.vanbaalenii_PYR-1 --ITDGWWVYLAAYAIFIGIHLSGVGEALKVMFVITAIALVGLVVFAVAA
* . .. :. : : : :: . .
Mflv_1998|M.gilvum_PYR-GCK AAFVLGLWP---------------GKGADFSNLTSHGGFMPLGFGAITVG
MSMEG_5473|M.smegmatis_MC2_155 AFYVLGVWP---------------DKDLDFSNLTAHGGFFPLGATAVTVG
MAB_4909|M.abscessus_ATCC_1997 TCYVLGLWP---------------GKKLDFSNLTVHEGFMPHGPGAIFSS
Mb0535|M.bovis_AF2122/97 TAFAFGLLP---------------GHGMDFSNLSAHGGFFPDGVGAVFAA
Rv0522|M.tuberculosis_H37Rv TAFAFGLLP---------------GHGMDFSNLSAHGGFFPDGVGAVFAA
MMAR_0862|M.marinum_M AAFAFGLLP---------------GHHMDFGNLTSHGGLFPMGVEPVFAT
MAV_4626|M.avium_104 AAYVIGLVP---------------GHHDGLTNLVSHGGFFPRGVGAVFAA
MUL_4508|M.ulcerans_Agy99 LLWTMGLWP---------------SATPGLGKLVDFGGFAPLGWGAVLAA
MLBr_01305|M.leprae_Br4923 TIFLGGRYPV-------------DGHNTGLSLWTSHGGLFPTGVAPLIVV
TH_0471|M.thermoresistible__bu AFFIKAANYTPFIPPAEAGGEAGRSLDQSLFSLITGAEGSSYGWYGLLAG
Mvan_3196|M.vanbaalenii_PYR-1 IPHFDSTNLT----------------DIAVTDAAGASALLPFGLLGIWAA
. . . * :
Mflv_1998|M.gilvum_PYR-GCK IVTVIFSMVGAEIATIAAAESQDPERAVAKAANSVILRILIFYVGAVLLL
MSMEG_5473|M.smegmatis_MC2_155 VVTVIFSMVGAEIATIAAAESSDPERAVAKAANSVILRIALFFVGSAFLL
MAB_4909|M.abscessus_ATCC_1997 IVIVIFSMVGAEIATIAAAESKDPAKAISQATNSVIYRVAIFFVGSIFLI
Mb0535|M.bovis_AF2122/97 IVVAIFSMTGTEVVTIAAAEAPDPQRAVQRAMSTVVARIVIFFVGSVFLL
Rv0522|M.tuberculosis_H37Rv IVVAIFSMTGTEVVTIAAAEAPDPQRAVQRAMSTVVARIVIFFVGSVFLL
MMAR_0862|M.marinum_M VVIAIFSMTGTEIITIAAAETPDPEYAVQRAMSTVVARIAVFFVGSVFLL
MAV_4626|M.avium_104 IVVVIFSMVGAEIVTVAAAESRDPRRAVQKATRSVVTRIGIFFVGSVFLL
MUL_4508|M.ulcerans_Agy99 VVPCVAFYTGAEIVTVAAAESAEPEGSVSRAMKSIVARIIAFYVGSILVV
MLBr_01305|M.leprae_Br4923 SSGVMFAYAAVELVGTAAGETVEPKKIMPRAINSVIARIAIFYVGSVILL
TH_0471|M.thermoresistible__bu ASIVFFAFIGFDIIATTAEETKNPQRDVARGIMATLGIVTVLYVAVSLVL
Mvan_3196|M.vanbaalenii_PYR-1 IPFAIWFFLAIEGVPLAAEETAEPERNVPKGIIAGMAVLLVTCVTVLVLT
. . : :* *: :* : :. : : : * .:
Mflv_1998|M.gilvum_PYR-GCK VLIVPWNDESVS--ASPFVAAFNAMGIPYADHVMNAVVLTAVLSCLNSGM
MSMEG_5473|M.smegmatis_MC2_155 VTILPWNSDQTV--ASPFVAAFTEMGIPYADHIMNAVVLTAVLSCLNSGM
MAB_4909|M.abscessus_ATCC_1997 AVIVPWNSPELG--TSPYVTAFKTMGIPAADHIMRVVVLTAVLSCLNSAM
Mb0535|M.bovis_AF2122/97 TVILPWNSLELG--ASPYVAALRHMGIGGADQIMNAVVLTAVLSCLNSGL
Rv0522|M.tuberculosis_H37Rv TVILPWNSLELG--ASPYVAALRHMGIGGADQIMNAVVLTAVLSCLNSGL
MMAR_0862|M.marinum_M VVILPWDSIDPG--ASPYVAAFQRMGIPGADQIMNAVVVTAVLSCLNSGL
MAV_4626|M.avium_104 VAILPWDSVELG--ASPYVAALKHLGLAGADQVMNAVVLTAVLSCLNSGL
MUL_4508|M.ulcerans_Agy99 VAVVPWNTKSVG--VSPYASALAVIGIPGVTTVMNAIVLTAVLSCLNSAL
MLBr_01305|M.leprae_Br4923 ALLLPYSAFKAS--ESPFVTFFSKVGFYGAGDLMNIVVLTAALSSLNAGL
TH_0471|M.thermoresistible__bu TGMVHYTELRAAGENANLATAFAANGIDWAAKVISIGALAGLTTVVIVLV
Mvan_3196|M.vanbaalenii_PYR-1 TGAGGAAAMSES--GNPLVEALGDS---GWAKVVNYIGLAGLIASFFSII
. . : :: ::. : . :
Mflv_1998|M.gilvum_PYR-GCK YTASRMLFVLAARREAPAALVKVTNRGVPANAILASSVVGFLCVIAAAVS
MSMEG_5473|M.smegmatis_MC2_155 YTASRMLFVLAARREAPPQLVAVTRRGVPATAILTSSVIGLICVIAAAFF
MAB_4909|M.abscessus_ATCC_1997 YTASRMLFVLAGRGEAPRSWLKVNARGVPVQAILASSFIGFVCVILAYFF
Mb0535|M.bovis_AF2122/97 YTASRMLFVLAARQEAPAQLVKVNRRGVPTFAIMGSSVVGFLCVIMAWVS
Rv0522|M.tuberculosis_H37Rv YTASRMLFVLAARQEAPAQLVKVNRRGVPTFAIMGSSVVGFLCVIMAWVS
MMAR_0862|M.marinum_M YTASRMMFVLAGRREAPASLVKVSRRGVPYVAILASSAVGFLCVIMAWVA
MAV_4626|M.avium_104 YTASRMLFVLAERGEAPARLVRLSGRGVPHIAILCSSAVGFLCVVMARVA
MUL_4508|M.ulcerans_Agy99 YTTSRMAFALTIHGDGPRFFTKLSRSGVPRRAIILGTTVGYASVVATYVW
MLBr_01305|M.leprae_Br4923 YATGRVMHSIAINGSGPKFTARMSKNGVPYGGILLAAVICLCGVALNAFN
TH_0471|M.thermoresistible__bu LGQTRVLFAMSRDGLLPRPLSKTGPRGTP---VRITVLVGALVAIAASVF
Mvan_3196|M.vanbaalenii_PYR-1 YAYSRQLFALSRAGYLPTVLSVTNSRKAPTLALIVPGVIGFLLSLIGQG-
* . :: * .* : :
Mflv_1998|M.gilvum_PYR-GCK PDTIFAFLLNSSGAIILFVYLLIAISQIVLRYRTPDSK---LRVKMWLFP
MSMEG_5473|M.smegmatis_MC2_155 PDTIFQFLLNSSGAVILFVYLLIAISQIVLRRRTDDSM---LKVKMWLFP
MAB_4909|M.abscessus_ATCC_1997 EHTVFLFLLNSSGAVILFVYLMIAISQYVLRRRTPEEK---LLVKMWGYP
Mb0535|M.bovis_AF2122/97 PATVFVFLLNSSGAVILFVYLLIALSQIVLRRQTSGQN---LGVRMWLFP
Rv0522|M.tuberculosis_H37Rv PATVFVFLLNSSGAVILFVYLLIALSQIVLRRQTSGQN---LGVRMWLFP
MMAR_0862|M.marinum_M PTTVFIFLLNSSGAVLLFVYLLIAFSQIVLRGRTPPEK---LRVRMWFFP
MAV_4626|M.avium_104 PNTVFLFLLNSSGAIILFVYWLIALSQIVLRRRTPAER---LSVKMWFFP
MUL_4508|M.ulcerans_Agy99 GDVVFEFLVNSYGAVALFVYLIIAISQVILRRRAEREDPGGLRLKMWLFP
MLBr_01305|M.leprae_Br4923 PGQAFEIVLSVAALGIIAGWGTIVLCQLRLHKMAKAGIMRRPRFRMPLAP
TH_0471|M.thermoresistible__bu PVGNLEEMVNIG---TLFAFALVSAGVIVLRRTRPDLK------RGFRVP
Mvan_3196|M.vanbaalenii_PYR-1 -----ALLLNMAVFGAALSYVLMMVSHIVLRRREPDMP------RPYRTP
::. : : *: : *
Mflv_1998|M.gilvum_PYR-GCK VLSGLTALGILAILVQMFIDT-ALRSQLVLSLLSWAVVIALFAANKWFVK
MSMEG_5473|M.smegmatis_MC2_155 VLSILTAAAIFAILVQMFVQGGDNRSALVLSLASWAVVIVLFWLNRMFVS
MAB_4909|M.abscessus_ATCC_1997 ALTILTAIGIVAILVAMGFQD-ATRTQLWTSLLSWGVILLLFAILRLTRR
Mb0535|M.bovis_AF2122/97 GLSIVTVTGIVAVLARMAFDY-AARSQLWLSLLSWAVVVGCYLVTTLVRR
Rv0522|M.tuberculosis_H37Rv GLSIVTVTGIVAVLARMAFDY-AARSQLWLSLLSWAVVVGCYLVTTLVRR
MMAR_0862|M.marinum_M WLPILTVVGIVVVLVRMAFDD-AAHSQFWLSMLSWVAVLGIYGITRLINR
MAV_4626|M.avium_104 VLSVLTLAGITAVLVQMAFDA-TARSQLWLSLLSWAVVVALYFVARSRGR
MUL_4508|M.ulcerans_Agy99 WLSYATIALMASVILAMAALS-ATRSRFLMSGVTLVLILATYEVRRRRRV
MLBr_01305|M.leprae_Br4923 YSGYLTLAFLFAVLVVMAFDKPIGTWTVASLIVIVPALIAGWYSIRKRVM
TH_0471|M.thermoresistible__bu FVPWLPLAAIAACLWLMLNLT-GLTWVRFLGWMALGLVLYFFYGRHHSML
Mvan_3196|M.vanbaalenii_PYR-1 GGVVTTGFALVIAVLAVIATFLVDSVAALCCLVVFAAFMAYFGIYSRHHL
. : : : .: :
Mflv_1998|M.gilvum_PYR-GCK KRPAEGDSGAPTGPPHRVLVLANRTVDSDELLAELSRIGADQTAEYLVVV
MSMEG_5473|M.smegmatis_MC2_155 RRPQTPDVAPTSEHPHRVLVLANQTVESDELLDELRRIGADRDTTYYVVV
MAB_4909|M.abscessus_ATCC_1997 RTPEPGERTTR---------------------------------------
Mb0535|M.bovis_AF2122/97 -PLNRPW-------------------------------------------
Rv0522|M.tuberculosis_H37Rv -PLNRPW-------------------------------------------
MMAR_0862|M.marinum_M NSRMRTRGQTSDV-------------------------------------
MAV_4626|M.avium_104 -VAAR---------------------------------------------
MUL_4508|M.ulcerans_Agy99 AVARNATVAARAFQPG-------------------------------VPM
MLBr_01305|M.leprae_Br4923 TIARERMGYTGPFP---------------------------------AIA
TH_0471|M.thermoresistible__bu GRGMTDISARRTG-------------------------------------
Mvan_3196|M.vanbaalenii_PYR-1 VANSPDEEFAALAAAEGELK------------------------------
Mflv_1998|M.gilvum_PYR-GCK PASAVDTGAAATHGPRDVTEATQEAATARLESTLAALRGKNLTVQGELGD
MSMEG_5473|M.smegmatis_MC2_155 PASPIDTGVANTHGPLDISEATQQAAQERLDSTLATLRSGDFEATGTLGE
MAB_4909|M.abscessus_ATCC_1997 --------------------------------------------------
Mb0535|M.bovis_AF2122/97 --------------------------------------------------
Rv0522|M.tuberculosis_H37Rv --------------------------------------------------
MMAR_0862|M.marinum_M --------------------------------------------------
MAV_4626|M.avium_104 --------------------------------------------------
MUL_4508|M.ulcerans_Agy99 PACAQRCG------------------------------------------
MLBr_01305|M.leprae_Br4923 NPPVQPSERSHSQNP-----------------------------------
TH_0471|M.thermoresistible__bu --------------------------------------------------
Mvan_3196|M.vanbaalenii_PYR-1 --------------------------------------------------
Mflv_1998|M.gilvum_PYR-GCK YRPLRALDHAVAEFGPDQIVIATLPPEFSMWHRFDVVDRARAQFTVPVTH
MSMEG_5473|M.smegmatis_MC2_155 YRPLRALAKAVETFRPDQIVISTLPPEESVWQRFDVVDRARAEHHLPVTH
MAB_4909|M.abscessus_ATCC_1997 --------------------------------------------------
Mb0535|M.bovis_AF2122/97 --------------------------------------------------
Rv0522|M.tuberculosis_H37Rv --------------------------------------------------
MMAR_0862|M.marinum_M --------------------------------------------------
MAV_4626|M.avium_104 --------------------------------------------------
MUL_4508|M.ulcerans_Agy99 --------------------------------------------------
MLBr_01305|M.leprae_Br4923 --------------------------------------------------
TH_0471|M.thermoresistible__bu --------------------------------------------------
Mvan_3196|M.vanbaalenii_PYR-1 --------------------------------------------------
Mflv_1998|M.gilvum_PYR-GCK VVATSAVGNQVPR
MSMEG_5473|M.smegmatis_MC2_155 VVSRVRATEPAP-
MAB_4909|M.abscessus_ATCC_1997 -------------
Mb0535|M.bovis_AF2122/97 -------------
Rv0522|M.tuberculosis_H37Rv -------------
MMAR_0862|M.marinum_M -------------
MAV_4626|M.avium_104 -------------
MUL_4508|M.ulcerans_Agy99 -------------
MLBr_01305|M.leprae_Br4923 -------------
TH_0471|M.thermoresistible__bu -------------
Mvan_3196|M.vanbaalenii_PYR-1 -------------