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MSGALGSTREITTRGIILGGLITLVFTAANVYLGLKVGLTFATSIPAAVISMGVLRLFANHSIVENNIVQ TIASAAGTLSAIIFVLPALIMIGWWSGFPYWTTVAVCGFGGLLGVMYSIPLRRALVTGSDLPYPEGVAGA EVLKIGASARGAEENRRGLSVIALGAVTAAGYSLLAALKVISNSLAVTFRLGSGATMAGASLSLALVGVG HLVGLGVGIAMIVGVLISYGVLLPMRTAGQLPQDGALADFVSRTFSSDVRFIGAGAIAVAAVWTFLKIAG PIMAGIAEAAVSARTRRRGEAVDLHERDIPIQVVGLVVLVSLIPIGLLLGDFTDHTPIAGRAGSIIAVSL LLIVTIGLVVASVCGYMAGLIGSSNSPISGVGILVVLLAALLIKWTYGPASDAQTPALVAYAVFTAAVIF GVATISNDNLQDLKTGQLVGATPWKQQVALVIGVTIGAAVMAPVLQLMQSAFGFQGAPGATGNALAAPQA ALISALAKGVFGGSLNWSLVGLGALIGIVVVVVDEVLTRTTATLRLPPLAVGMGMYLPISLTLVIPVGAV LGRIYDSWAQRSGDEDESKRRMGVMLATGLIVGESLFGVAFAGIVVATGTEDPLAILGDGFTHWAELLGL FVFAAMIALLYRYVRAAASYRPTTPGQEPEPLSGRAG
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. marinum M | MMAR_3714 | - | - | 100% (667) | hypothetical protein MMAR_3714 |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb2417 | - | 0.0 | 71.84% (515) | hypothetical protein Mb2417 |
| M. gilvum PYR-GCK | - | - | - | - | - |
| M. tuberculosis H37Rv | Rv2395 | - | 0.0 | 75.26% (667) | integral membrane protein |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | MAB_4577c | - | 1e-05 | 28.25% (177) | NAD(P) transhydrogenase, beta subunit PntB |
| M. avium 104 | MAV_4899 | - | 5e-06 | 25.67% (374) | transporter, major facilitator family protein |
| M. smegmatis MC2 155 | MSMEG_1311 | - | 0.0 | 65.94% (646) | oligopeptide transporter, OPT family protein |
| M. thermoresistible (build 8) | - | - | - | - | - |
| M. ulcerans Agy99 | MUL_3265 | narK3 | 3e-05 | 24.48% (384) | integral membrane nitrite extrusion protein NarK3 |
| M. vanbaalenii PYR-1 | - | - | - | - | - |
CLUSTAL 2.0.9 multiple sequence alignment
Mb2417|M.bovis_AF2122/97 --------------------------------------------------
Rv2395|M.tuberculosis_H37Rv ------MSGATVGAREITIRGVVLGALITLVFTAANVYLGLRVGLTFATS
MMAR_3714|M.marinum_M ------MSGALGSTREITTRGIILGGLITLVFTAANVYLGLKVGLTFATS
MSMEG_1311|M.smegmatis_MC2_155 MTSESTATPATPTLRELTVRGILLGGVITLVFTAANVYLGLKVGLTFATA
MAV_4899|M.avium_104 --------------------------------------------------
MUL_3265|M.ulcerans_Agy99 --------------------------------------------------
MAB_4577c|M.abscessus_ATCC_199 --------------------------------------------------
Mb2417|M.bovis_AF2122/97 --------------------------------------------------
Rv2395|M.tuberculosis_H37Rv IPAAVISMGVLRLFANHSVVENNIVQTIASAAGTLSSIIFVLPALLMIGW
MMAR_3714|M.marinum_M IPAAVISMGVLRLFANHSIVENNIVQTIASAAGTLSAIIFVLPALIMIGW
MSMEG_1311|M.smegmatis_MC2_155 IPAAVISMAILRNFRDHSIVENNIVQTVASAAGTLSAIIFVLPGLVMIGW
MAV_4899|M.avium_104 --------------------------------------------------
MUL_3265|M.ulcerans_Agy99 --------------------------------------------------
MAB_4577c|M.abscessus_ATCC_199 --------------------------------------------------
Mb2417|M.bovis_AF2122/97 --------------------------------------------------
Rv2395|M.tuberculosis_H37Rv WSGFPYWTTAAVCALGGILGVMYSIPLRRALVTGSDLPYPEGVAGAEVLK
MMAR_3714|M.marinum_M WSGFPYWTTVAVCGFGGLLGVMYSIPLRRALVTGSDLPYPEGVAGAEVLK
MSMEG_1311|M.smegmatis_MC2_155 WTGFPYWITVAVCAVGGILGVMYSIPLRRALVTGSDLPYPEGVAAAEVLK
MAV_4899|M.avium_104 --------------------------------------------------
MUL_3265|M.ulcerans_Agy99 --------------------------------------------------
MAB_4577c|M.abscessus_ATCC_199 ---------------------------------------------MSSES
Mb2417|M.bovis_AF2122/97 -------MEHNRRGIGVIALGAAAAAGYALLASLRVINNSLSATFRVGSG
Rv2395|M.tuberculosis_H37Rv IGDSAREMEHNRRGIGVIALGAAAAAGYALLASLRVINNSLSATFRVGSG
MMAR_3714|M.marinum_M IGASARGAEENRRGLSVIALGAVTAAGYSLLAALKVISNSLAVTFRLGSG
MSMEG_1311|M.smegmatis_MC2_155 VGERTEGAEDNRIGLRIITFGSIVSVAFALLANLKVLANSITAYFRVGAG
MAV_4899|M.avium_104 ----------MGRDHRITDWNPEDAAAWEAGNKRIARRNLLCTIAGDHVA
MUL_3265|M.ulcerans_Agy99 ----------MGRSRHIAHWDPEDVQAWEAGNKAIARRNLVFSIATMHVG
MAB_4577c|M.abscessus_ATCC_199 LNYIVDVLYIAAFALFIYGLSGLTGPKTAVRGNWIAAVGMGIAVLATLIK
: . . .
Mb2417|M.bovis_AF2122/97 ATMIGASLSLALIGVGHLVGVTVGVAMIVGLAIAFGVMLPIRTAGQLPPD
Rv2395|M.tuberculosis_H37Rv ATMIGASLSLALIGVGHLVGVTVGVAMIVGLAIAFGVMLPIRTAGQLPPD
MMAR_3714|M.marinum_M ATMAGASLSLALVGVGHLVGLGVGIAMIVGVLISYGVLLPMRTAGQLPQD
MSMEG_1311|M.smegmatis_MC2_155 GSMFGASLSFALIGVGHLVGMTVGIAMLVGLVISFGIILPFRTIGDFAGS
MAV_4899|M.avium_104 FSIWTLWPVMALFMPAAVYGFSAGDKLLLGAVATL-----VGGCARIPYT
MUL_3265|M.ulcerans_Agy99 FSIWTLWSVMVLFMPQSVYGISAANKLLLGATATL-----VGGCVRIPYV
MAB_4577c|M.abscessus_ATCC_199 VSESATTLDWILIGAGLGIGVVLGIPPALKTKMTA-----MPQLVALFNG
: *. *. . : : . :
Mb2417|M.bovis_AF2122/97 GDYAVAVARIFSTDVRFIGAGAIAVAAAWTFLKILGPILRGIADAAVSAR
Rv2395|M.tuberculosis_H37Rv GDYAVAVARIFSTDVRFIGAGAIAVAAAWTFLKILGPILRGIADAAVSAR
MMAR_3714|M.marinum_M GALADFVSRTFSSDVRFIGAGAIAVAAVWTFLKIAGPIMAGIAEAAVSAR
MSMEG_1311|M.smegmatis_MC2_155 ESVADVISSAFANEVRFVGAGAIAVGAVWTLLKILRPIVKGITEALVSAR
MAV_4899|M.avium_104 LGIAAFGGRKWTT----FSAVVLLIPTVGTIVLLANPGLPLWLFVLCAAL
MUL_3265|M.ulcerans_Agy99 MATARFGGRNWAT----FSSLVLLVPTVGAIVLLANPGLPLWPYLVCAAL
MAB_4577c|M.abscessus_ATCC_199 VGGGTVALIAWSEFIETKGFSEFKPDQSPTVALVVGSLFAAIIGSVSFWG
. :: . : :. : . .
Mb2417|M.bovis_AF2122/97 TRRRGQAVGQTERDIPIHIVAMVVLLSLIPIGWLLADFTDGTPLDDRRPG
Rv2395|M.tuberculosis_H37Rv TRRRGQAVGQTERDIPIHIVAMVVLLSLIPIGWLLADFTDGTPLDDRRPG
MMAR_3714|M.marinum_M TRRRGEAVDLHERDIPIQVVGLVVLVSLIPIGLLLGDFTDHTPIAGRAGS
MSMEG_1311|M.smegmatis_MC2_155 ERREGQLVDITQRDIPFPIVVATIVVMLLPIAVLLWEFSRGTVLQGSSAG
MAV_4899|M.avium_104 TGLGG----------------GNYAASLANVNAFYPQRLKGAAMA-VNAG
MUL_3265|M.ulcerans_Agy99 SGVGG----------------GNYSASLANVEAFYPQRLKGVALG-LTGG
MAB_4577c|M.abscessus_ATCC_199 S-----------------------LVAFAKLQESIPKNVEKRLVASAKLF
: : . :
Mb2417|M.bovis_AF2122/97 AIAAGVLLVLVIGLMVAA--VCGYMAGLIGSSNSPISGVGILVVVLAGLL
Rv2395|M.tuberculosis_H37Rv AIAAGVLLVLVIGLMVAA--VCGYMAGLIGSSNSPISGVGILVVVLAGLL
MMAR_3714|M.marinum_M IIAVSLLLIVTIGLVVAS--VCGYMAGLIGSSNSPISGVGILVVLLAALL
MSMEG_1311|M.smegmatis_MC2_155 IIVASVVFVFVIGLVIAA--VCGYMAGLIGSSNSPISGVGILTVLIAALL
MAV_4899|M.avium_104 VANLGVAVIQLVGLLVLA--TAGHQA--------PYWVCAVYLVFLAAVA
MUL_3265|M.ulcerans_Agy99 IGNLGVTAIQAVGLLVLA--TAGHEA--------PYWVCAVYLVLIAIAG
MAB_4577c|M.abscessus_ATCC_199 QASNIVLLLAAVGTAVYIGLHPG----------LPVWWIVAVLVFAGVMG
: : :* : * * *. .
Mb2417|M.bovis_AF2122/97 IKTAYGPATGSQIPALVAYTVFTAALVFGVATISNDNLQDLKTGQLVGAT
Rv2395|M.tuberculosis_H37Rv IKTAYGPATGSQIPALVAYTVFTAALVFGVATISNDNLQDLKTGQLVGAT
MMAR_3714|M.marinum_M IKWTYGPASDAQTPALVAYAVFTAAVIFGVATISNDNLQDLKTGQLVGAT
MSMEG_1311|M.smegmatis_MC2_155 IKIVFGPTNDDQATALVAFTLFAAAITFGVATISNDNLQDLKTGQLVGAT
MAV_4899|M.avium_104 IAAAMFMDDINHGTQLS----TMRSILFERDTHVISLLYIATFGSWIGFS
MUL_3265|M.ulcerans_Agy99 LGAALFMENLTHVIEVG----HVRSVLAVPDTWSVSFLYMCASGSFIGFA
MAB_4577c|M.abscessus_ATCC_199 LFVVFPIGG-ADMPVVISLLNAMTGLSAAAAGLALNNTAMIVAGMIVGAS
: . . : .: . * :* :
Mb2417|M.bovis_AF2122/97 -PWKQQVALIIGVLVGSVVMAPILQLMQAGFGFQGAPGATANALAAPQAA
Rv2395|M.tuberculosis_H37Rv -PWKQQVALIIGVLVGSVVMAPILQLMQAGFGFQGAPGATANALAAPQAA
MMAR_3714|M.marinum_M -PWKQQVALVIGVTIGAAVMAPVLQLMQSAFGFQGAPGATGNALAAPQAA
MSMEG_1311|M.smegmatis_MC2_155 -PWKQQVALVIGVLFGSAIIPPVLELMQTAFGFLGAPGASENALAAPQAA
MAV_4899|M.avium_104 -FAFGQVMQVN--FLENGESAKHAALHAAQLAFIGPLLGSVARIYGGRLA
MUL_3265|M.ulcerans_Agy99 -FVFGQVLQFN--LLAGGQSTAQASLHAAEIAFVGPLLGSLARIVGGKLG
MAB_4577c|M.abscessus_ATCC_199 GSILTNLMAVAMNRSIPAIVFGSFGGSDAGAAGGAAEQGTVKATSASDAA
:: . : . .. .: . .
Mb2417|M.bovis_AF2122/97 LMSALAKGVFGGSLNWSLVGVGALTGVIAVALDETLAKTTTNLRLPPLAV
Rv2395|M.tuberculosis_H37Rv LMSALAKGVFGGSLNWSLVGVGALTGVIAVALDETLAKTTTNLRLPPLAV
MMAR_3714|M.marinum_M LISALAKGVFGGSLNWSLVGLGALIGIVVVVVDEVLTRTTATLRLPPLAV
MSMEG_1311|M.smegmatis_MC2_155 LISSLAKGVFGGSLDWSLIGLGAAIGVVVVIIDEILHRTSR-FALPPLAV
MAV_4899|M.avium_104 DRVGGSRVTLG---VLAAMTLAAGLLVIVSTVDDQHAGA----HSVSMIG
MUL_3265|M.ulcerans_Agy99 DRFGGGRVTLG---VFVAMILSAALLVAVNTHADLNHGAGGRMTAATLIG
MAB_4577c|M.abscessus_ATCC_199 IQMAYANQVIVVP-GYGLAVAQAQHTVKEMADLLESKGVEVKYAIHPVAG
. .. .: * : . .:
Mb2417|M.bovis_AF2122/97 GMGMYLPAALTLMIPIGAFLGRIYDSWARWSG--DDDERKKRLGVMLATG
Rv2395|M.tuberculosis_H37Rv GMGMYLSAALTLMIPIGAFLGRIYDSWARWSG--DDDERKKRLGVMLATG
MMAR_3714|M.marinum_M GMGMYLPISLTLVIPVGAVLGRIYDSWAQRSG--DEDESKRRMGVMLATG
MSMEG_1311|M.smegmatis_MC2_155 GMGMYLPMSLILVIAIGAVIGYVYNRWAIRTG--GDVQRKKRLGVLLATG
MAV_4899|M.avium_104 YVVGFMVLFILSGMGNGSVFKLIPSVYEARSRGRDTSEDERRQWARAMAG
MUL_3265|M.ulcerans_Agy99 YVSGFIALFIFCGMGKGTVFELIPSIFAERSQHLDISDMQRRQWARIVSG
MAB_4577c|M.abscessus_ATCC_199 RMPGHMNVLLAEADVEYDAMKEMDDINGEFNR----TDVTIVIGANDVTN
: .: : : : . . : . :.
Mb2417|M.bovis_AF2122/97 LIVGESLYGVLFAVIVATTGKEEPLAMVGDGFRF-ASQPLGAIVFAGLLA
Rv2395|M.tuberculosis_H37Rv LIVGESLYGVLFAVIVATTGKEEPLAMVGDGFRF-ASQPLGAIVFAGLLA
MMAR_3714|M.marinum_M LIVGESLFGVAFAGIVVATGTEDPLAILGDGFTH-WAELLGLFVFAAMIA
MSMEG_1311|M.smegmatis_MC2_155 LIVGESLYGVVFAGIVAGTGNEDPLAIFTGNDGN-FAQIFGIVAFAAVIL
MAV_4899|M.avium_104 SLIGICSAVGAFGGVAINLALRQSYLSTGTETSA-YWTFMASYVVAAIMT
MUL_3265|M.ulcerans_Agy99 ALIGFAGSVGALGGVGINLALRQSYVHSGTETPA-FWAFLVCYLCAAALT
MAB_4577c|M.abscessus_ATCC_199 PAARNDPSSPIHGMPILNVDESRSVIVLKRSMSSGYAGIENPLFFQPQTS
. .
Mb2417|M.bovis_AF2122/97 WLYQRTRVTASYRLAAPAGSSKPLPDLPG
Rv2395|M.tuberculosis_H37Rv WLYQRTRVTASYRLAAPAGSSKPLPDLPG
MMAR_3714|M.marinum_M LLYRYVRAAASYRPTTPGQEPEPLSGRAG
MSMEG_1311|M.smegmatis_MC2_155 WLYKRTQTLSSREVGAKSGQ---------
MAV_4899|M.avium_104 WLVYVR--RPVT-APGVSLPETQAARL--
MUL_3265|M.ulcerans_Agy99 WARYVRPRSPVASAPRKPNEDPQLSGAAA
MAB_4577c|M.abscessus_ATCC_199 MLFGDAKKSVSAVIEELKAL---------