For questions or suggestions e-mail us at: ioerger@cs.tamu.edu
TSSSSTADVVVVGGGTVGAWTAVLLAESGVEHVVLVEAATLGDGASSRAAGMVRAQGGTETAIRLGMRAQ EFYRESGDRFPLDCGFRAQGYLMPCFSEAEVQQAHARIALQKDLGLEVEWLSSSDIDARETGLTPGVTMG ASYAPGDGYIDAPRNVLAYSAALAVHRVDVREHCTFLGLRTESGRVVGVDTSAGPVDTGHVVLTGGPQLS EVGSRAGGRIPAGGTRHQVVVTEPLPVDVHALPMVFDLMSGIYWRPGESGGLLWGMSNPEELPGAAREFD WVYYDKMRHRIGELLPVVKGLGLRRAWAATIDYTPDHLPILGPLIGDDGPIDGTVVASPAGHGMMWGPAV AQVAADLTTTGTCAWLDLTDLGLDRFDAEGHSRVAPEPISLPFPEQVSRAPS*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. smegmatis MC2 155 | MSMEG_0665 | - | - | 100% (403) | sarcosine oxidase subunit beta, putative |
| M. smegmatis MC2 155 | MSMEG_6264 | - | 4e-33 | 29.32% (399) | putative oxidoreductase |
| M. smegmatis MC2 155 | MSMEG_0637 | - | 3e-07 | 23.69% (401) | iron-sulfur binding oxidoreductase |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | - | - | - | - | - |
| M. gilvum PYR-GCK | Mflv_1296 | - | 2e-35 | 30.58% (412) | FAD dependent oxidoreductase |
| M. tuberculosis H37Rv | - | - | - | - | - |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | MAB_2651c | - | 4e-12 | 24.06% (374) | oxidoreductase |
| M. marinum M | MMAR_4420 | gcvT_2 | 2e-06 | 22.79% (408) | aminomethyltransferase GcvT_2 |
| M. avium 104 | - | - | - | - | - |
| M. thermoresistible (build 8) | TH_1303 | - | 2e-05 | 31.30% (131) | iron-sulfur binding oxidoreductase |
| M. ulcerans Agy99 | - | - | - | - | - |
| M. vanbaalenii PYR-1 | Mvan_5513 | - | 3e-35 | 29.17% (408) | FAD dependent oxidoreductase |
CLUSTAL 2.0.9 multiple sequence alignment
Mflv_1296|M.gilvum_PYR-GCK ---------------------MTETADVVIVGGGLEGAAAAWALSRRGVT
Mvan_5513|M.vanbaalenii_PYR-1 ---------------------MTETADVVIVGGGLEGAAAAWALSRRGVT
MSMEG_0665|M.smegmatis_MC2_155 ------------------MTSSSSTADVVVVGGGTVGAWTAVLLAESGVE
MMAR_4420|M.marinum_M -----------------------MGPKIVIVGAGIVGASLADELTARGVI
MAB_2651c|M.abscessus_ATCC_199 MEYLFDTGWVDRPEVTAAALQGEIRCDVAVIGAGVGGMAAGLRLAERG-V
TH_1303|M.thermoresistible__bu MTSLWLADRTNQPPPPRTLDAGDRRADVVVVGAGITGLITAVLLARGG-K
.:.::*.* * . *: *
Mflv_1296|M.gilvum_PYR-GCK DVVVCERSTVG--SGMTGKSSGIVRCHYGVS-------------SLAAMA
Mvan_5513|M.vanbaalenii_PYR-1 DVVVAERNTVG--SGMTGKSSGIVRCHYGVS-------------SLAAMA
MSMEG_0665|M.smegmatis_MC2_155 HVVLVEAATLG--DGASSRAAGMVRAQGGTE-------------TAIRLG
MMAR_4420|M.marinum_M DVTVVDRGPLFTTGGSTSHAPGLVFATNPSK-------------TMSAFA
MAB_2651c|M.abscessus_ATCC_199 DVVVLEAGICG--WGASSRNGGYLTDALSGDPRMLSALHRRRLPGVMRFG
TH_1303|M.thermoresistible__bu DVLVVEAAYVG--AGATGNTTAKISVLQGSRMSKILAKHGPR--RARQYV
.* : : * :.. . :
Mflv_1296|M.gilvum_PYR-GCK ADGLEVFEQAQDIFGTDIGFRQTGYVVG--VGEQNVDALRKSLAAQRSVG
Mvan_5513|M.vanbaalenii_PYR-1 ADGLEVFENGEDIFGTDIGFRQTGYVVG--VGEQNVESLRKSLAAQRAVG
MSMEG_0665|M.smegmatis_MC2_155 MRAQEFYRESGDRFPLDCGFRAQGYLMPC-FSEAEVQQAHARIALQKDLG
MMAR_4420|M.marinum_M RYTVDKFSGLHHRDG--AVFNRVGGLEVA-TTAERWADLHRKAGWAQAWG
MAB_2651c|M.abscessus_ATCC_199 QSALRFAEDLIERHQIECDYNRVGWVSMASTTRHRAKNAERAAEVLRSLG
TH_1303|M.thermoresistible__bu EGNLEGLEWLVRHCAAHGLSVQREDAYTFAQSLQGVPAARTEYLAAKIAG
. : *
Mflv_1296|M.gilvum_PYR-GCK VETEEIDESEVARLWPFADLTPFAAFGWEARGGYGDAYQTAQAFSTSARA
Mvan_5513|M.vanbaalenii_PYR-1 VDTEEIDKDEVAKLWPFADLTPFAAFGWEARGGYGDAYQTAQAFSTAARA
MSMEG_0665|M.smegmatis_MC2_155 LEVEWLSSSDIDARETGLTPGVTMGASYAPGDGYIDAPRNVLAYSAALAV
MMAR_4420|M.marinum_M VPGRLVGPDQCVELHPLLDRAGILGGFHTPSDGLASAVRAVEAQARRAIA
MAB_2651c|M.abscessus_ATCC_199 ADAEYVDGREFG------LPHAFLGGVYEPHGGLCNAGKYALGLRKVLLA
TH_1303|M.thermoresistible__bu LDVEWVDDAEGG------VPFPFHGAVRLADQAQFDPMPLLDSLVVELEE
. :. : . . . .. .
Mflv_1296|M.gilvum_PYR-GCK AGVRVRQGTAVAGLLADADRVTGVRLADGSEISAGTTVVATGVWTRPFLS
Mvan_5513|M.vanbaalenii_PYR-1 AGARVRQGTAVTDLLVDGDRVTGVRTADGSEIFAGTVVVATGVWTRPFLA
MSMEG_0665|M.smegmatis_MC2_155 HRVDVREHCTFLGLRTESGRVVGVDTSAG-PVDTGHVVLTGGPQLSEVGS
MMAR_4420|M.marinum_M RGAVFLAETEVQRVADHNGLVTGVHTSRG-VIEADIVVCAAGFWGAQLAK
MAB_2651c|M.abscessus_ATCC_199 SGARVYEQTPVQDLES-SGSAVVITVPGGKVRADRVLLATNGYSADLPFA
TH_1303|M.thermoresistible__bu RGGRLVQGLRVHKVSGRGDGLTLHARSGAGDEFDLRADRCVLATGIPILD
. . : . . . .
Mflv_1296|M.gilvum_PYR-GCK AHGIDMPIRVVREQIVMIDPGIDEA------AVGRLPVFSDLVSLQYVRP
Mvan_5513|M.vanbaalenii_PYR-1 RYGIDVPIRVIREQIVLIDPGV---------EVGKVPVFSDLVSLQYVRP
MSMEG_0665|M.smegmatis_MC2_155 RAGGRIPAGGTRHQVVVTEPLP--V------DVHALPMVFDLMSGIYWRP
MMAR_4420|M.marinum_M QVGLVLPLVPMAHQYAKTGQVAPLVGRNTEDAPASLPILRHQDGDLYFRE
MAB_2651c|M.abscessus_ATCC_199 PPRLAAPLWVSLLETEPIDPERLDSTG---WTNGAGFVSNNNIVSNFRKT
TH_1303|M.thermoresistible__bu RGGFFARLEPNRSYCLAYEVPG--------EITRGMYISTDSPTRSLRYA
: .
Mflv_1296|M.gilvum_PYR-GCK ELG--GEILFGNSDLPGYDAIAPADPD----AYLNRATDDFVDLTVDKVG
Mvan_5513|M.vanbaalenii_PYR-1 EVG--GEILFGNSDLPGYDAIDPADPD----DYLNRATDGFVDLTVDKVG
MSMEG_0665|M.smegmatis_MC2_155 GES--GGLLWGMS--------NPEELP----GAAREFDWVYYDKMRHRIG
MMAR_4420|M.marinum_M HVDRLGIGSYGHQPMPVDMSTLLADTAGEPMPSMLPFTEEDFEPAWRECV
MAB_2651c|M.abscessus_ATCC_199 PHN---TIVFGTRN-----VQAPQGPLG-----ARTTDPAVAKDLLRGFR
TH_1303|M.thermoresistible__bu PTGAGDLLIVGGAGHPVGHEKNPASSVA----ELDEWARRHFPGAQQRYF
. *
Mflv_1296|M.gilvum_PYR-GCK TRFPGFPDASITGSYAGCYDVTPDWNPVIS-----RGPLDGLVIAAGFSG
Mvan_5513|M.vanbaalenii_PYR-1 TRFPGFPDAAISGSYAGCYDVTPDWNPIIS-----VAPLDGLVIAAGFSG
MSMEG_0665|M.smegmatis_MC2_155 ELLPVVKGLGLRRAWAATIDYTPDHLPILGPLIGDDGPIDGTVVAS-PAG
MMAR_4420|M.marinum_M RLLPALGDTKVDEGFNGIFSFTPDGYSLLG----EHRELGGFWVAEAVWV
MAB_2651c|M.abscessus_ATCC_199 EAFPSLRDVATQKTWGGWIGMSPTLLPVAG------QSSSRVLYTNGCNG
TH_1303|M.thermoresistible__bu WSAQDYSPIDDLPYVGPILPGNESIFVAIG--FDKWGMTNGAAAALALSS
. . . :
Mflv_1296|M.gilvum_PYR-GCK HGFKIAPAVGRLVADLVVDGHGSDPRIPASDFRFSRFAEN----------
Mvan_5513|M.vanbaalenii_PYR-1 HGFKIAPAVGRLVADIVVDGHSSDSRIPASDFRFSRFAED----------
MSMEG_0665|M.smegmatis_MC2_155 HGMMWGPAVAQVAADLTTTG--TCAWLDLTDLGLDRFDAEG------HSR
MMAR_4420|M.marinum_M T---HSAGVAKAVAEWIVDGTPSIDVHECDLYRFEDFARSPRFIDETCAQ
MAB_2651c|M.abscessus_ATCC_199 YGMTQAPYLATLLADR-LAGDEMHEDLRAVWYDHNVFPPNP-------QF
TH_1303|M.thermoresistible__bu RILGGRTDWAEAFASWSPHEVSGIPKAMMLNLQVGMYLARG-------WL
. . *. :
Mflv_1296|M.gilvum_PYR-GCK ---DPLKTPYPYVGAGQMR-------------------------------
Mvan_5513|M.vanbaalenii_PYR-1 ---DPLKTPYPYVGAGQMR-------------------------------
MSMEG_0665|M.smegmatis_MC2_155 VAPEPISLPFPEQVSRAPS-------------------------------
MMAR_4420|M.marinum_M AFVEVYDIVHPHQYRSALRGLRTSPFHHRQRELGAYFYEGGGWERPAWFQ
MAB_2651c|M.abscessus_ATCC_199 SALGARALWTLDRITDQVDRLRS---------------------------
TH_1303|M.thermoresistible__bu TPVTRTGDRSPDDGCGVVSGPPWHLQARSRVDG---------------VE
Mflv_1296|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_5513|M.vanbaalenii_PYR-1 --------------------------------------------------
MSMEG_0665|M.smegmatis_MC2_155 --------------------------------------------------
MMAR_4420|M.marinum_M ANAELVRELAGRNVAFPERDDWAARYWSPIAIAEAQWTRERVALYDMTPL
MAB_2651c|M.abscessus_ATCC_199 --------------------------------------------------
TH_1303|M.thermoresistible__bu HRVSPVCPHLGGIVNWNDADQAWECPLHGSRFAPDGALLEGPATRGLTAS
Mflv_1296|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_5513|M.vanbaalenii_PYR-1 --------------------------------------------------
MSMEG_0665|M.smegmatis_MC2_155 --------------------------------------------------
MMAR_4420|M.marinum_M TRYEVSGAGAVDLLQRLTTNDIDKGVGSVTYTLMLDETGGIRSDLTVARL
MAB_2651c|M.abscessus_ATCC_199 --------------------------------------------------
TH_1303|M.thermoresistible__bu --------------------------------------------------
Mflv_1296|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_5513|M.vanbaalenii_PYR-1 --------------------------------------------------
MSMEG_0665|M.smegmatis_MC2_155 --------------------------------------------------
MMAR_4420|M.marinum_M GTARFQVGANGPQDFDWLSRHLPQDGSVTLRDITGATCCIGVWGPAARDL
MAB_2651c|M.abscessus_ATCC_199 --------------------------------------------------
TH_1303|M.thermoresistible__bu --------------------------------------------------
Mflv_1296|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_5513|M.vanbaalenii_PYR-1 --------------------------------------------------
MSMEG_0665|M.smegmatis_MC2_155 --------------------------------------------------
MMAR_4420|M.marinum_M VQPLCRDDLSHQAFPYFRLLQTYLEAIPVTMLRVSYVGELGWEIYTEASY
MAB_2651c|M.abscessus_ATCC_199 --------------------------------------------------
TH_1303|M.thermoresistible__bu --------------------------------------------------
Mflv_1296|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_5513|M.vanbaalenii_PYR-1 --------------------------------------------------
MSMEG_0665|M.smegmatis_MC2_155 --------------------------------------------------
MMAR_4420|M.marinum_M GGALWDLLWAAGAGHQAIAAGRIAFNSLRMEKGYRAWGTDMTAEHRPDEA
MAB_2651c|M.abscessus_ATCC_199 --------------------------------------------------
TH_1303|M.thermoresistible__bu --------------------------------------------------
Mflv_1296|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_5513|M.vanbaalenii_PYR-1 --------------------------------------------------
MSMEG_0665|M.smegmatis_MC2_155 --------------------------------------------------
MMAR_4420|M.marinum_M GLGFAVRMSKDFIGKAALVDAAARKVLQCLVFDDPAAAALGKEPVLAGDV
MAB_2651c|M.abscessus_ATCC_199 --------------------------------------------------
TH_1303|M.thermoresistible__bu --------------------------------------------------
Mflv_1296|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_5513|M.vanbaalenii_PYR-1 --------------------------------------------------
MSMEG_0665|M.smegmatis_MC2_155 --------------------------------------------------
MMAR_4420|M.marinum_M CIGFVTSAGYSPTIGRTIAYAWLPAESSIGDTVTVDHRGRRYPASVHQQP
MAB_2651c|M.abscessus_ATCC_199 --------------------------------------------------
TH_1303|M.thermoresistible__bu --------------------------------------------------
Mflv_1296|M.gilvum_PYR-GCK -----------
Mvan_5513|M.vanbaalenii_PYR-1 -----------
MSMEG_0665|M.smegmatis_MC2_155 -----------
MMAR_4420|M.marinum_M VVDPESTRIRR
MAB_2651c|M.abscessus_ATCC_199 -----------
TH_1303|M.thermoresistible__bu -----------