For questions or suggestions e-mail us at: ioerger@cs.tamu.edu
MSNNYDALVIGGGHNGLVSAAYLARAGARTLVLESRSSLGGAATTEAPWDDAPHLRVTRLSYVMSLMPPT IVRDLALERHGYKVHPMGPYYQAFPEGGSLTIYEDDPARTYEQLSRFSKKDADAWPKWNAWLEGIADVMG PLLTQVPPNIGSHRPADLLDLAKLAWGQRGITSRAVADITRLLTMSIADLLDDWFESPQIKGALAVNGVI GTWAGPYEPGTAYVMAHHSIGDVGDGQLGSWGFPEGGMGAVSAAIACSARSFGAEIRTNARVSRLLVRNG RVEGAVLDNGDEIHAPVVVTTLHPKTAFLDHIPRTELPQDFVGDIEHWKSRSGVVKINLALAELPNFTAD PSSGIAEHHTGSVEMAPTMEFIEAAFQDARNGKPALLPFSDGVIPTTLDTTLNPDGTHIMSLFTQWVPAE WAAEPHTEELDAYADRLIELYDQVAPGFKASITHRDIVGPYDMEHEYGLIGGNIFHGELSLEQLFHMRPA PGYADYRTPIAGLYNGSSATHAGGGVCGIPGWQAARAVLADKKRARRSEALRKRLPAALGGRS
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. smegmatis MC2 155 | MSMEG_0664 | - | - | 100% (553) | FAD dependent oxidoreductase |
| M. smegmatis MC2 155 | MSMEG_5667 | - | 1e-35 | 27.80% (554) | phytoene dehydrogenase |
| M. smegmatis MC2 155 | MSMEG_5400 | - | 2e-35 | 29.56% (548) | dehydrogenase |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb3859c | - | 6e-42 | 27.64% (550) | putative dehydrogenase |
| M. gilvum PYR-GCK | Mflv_1677 | - | 1e-44 | 28.76% (539) | FAD dependent oxidoreductase |
| M. tuberculosis H37Rv | Rv3829c | - | 6e-42 | 27.64% (550) | dehydrogenase |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | MAB_0948c | - | 9e-29 | 27.03% (555) | hypothetical protein MAB_0948c |
| M. marinum M | MMAR_5383 | - | 3e-48 | 29.12% (546) | dehydrogenase |
| M. avium 104 | MAV_0198 | - | 3e-45 | 28.26% (545) | FAD dependent oxidoreductase, putative |
| M. thermoresistible (build 8) | TH_0456 | - | 2e-23 | 27.29% (524) | PROBABLE OXIDOREDUCTASE |
| M. ulcerans Agy99 | MUL_2934 | - | 1e-44 | 29.37% (538) | dehydrogenase |
| M. vanbaalenii PYR-1 | Mvan_0988 | - | 2e-46 | 29.42% (537) | FAD dependent oxidoreductase |
CLUSTAL 2.0.9 multiple sequence alignment
Mb3859c|M.bovis_AF2122/97 -----MTGYDAIVIGAGHNGLTAAVLLQRAGLRTACLDAKRYAGGMASTV
Rv3829c|M.tuberculosis_H37Rv -----MTGYDAIVIGAGHNGLTAAVLLQRAGLRTACLDAKRYAGGMASTV
MMAR_5383|M.marinum_M -----MAEYDAIVIGAGHNGLTAAVLLQRAGLRTLCLDAKLYAGGMASTV
MAV_0198|M.avium_104 -----MNDYDAIVIGAGHNGLTAAVLLQKAGLRTLCLDAKLYAGGMASTV
Mflv_1677|M.gilvum_PYR-GCK -----MTDFDAIVVGAGHNGLTAAALLQQAGLRTVCLDFKLYAGGMASTV
MUL_2934|M.ulcerans_Agy99 -----MTDYDAIVVGAGHNGLTAAAVLQRAGLRTLCMEANTYAGGMAATV
Mvan_0988|M.vanbaalenii_PYR-1 -----MSDYDAIIIGAGHNGLTAATVLQRAGLRTVLLEANTYAGGMAATV
MAB_0948c|M.abscessus_ATCC_199 MGLSESDRYDTVIVGGGHNALTAAAYLARAGQRVMLLERLDVFGGAAISA
TH_0456|M.thermoresistible__bu ---------------------------------VLVLERLDHVGGAAVSA
MSMEG_0664|M.smegmatis_MC2_155 ----MSNNYDALVIGGGHNGLVSAAYLARAGARTLVLESRSSLGGAATTE
. :: ** * :
Mb3859c|M.bovis_AF2122/97 ELFDGYRFDIAGSVQFPTSSAVSSELGLDSLPTVDLEVMSVALRGVGDD-
Rv3829c|M.tuberculosis_H37Rv ELFDGYRFEIAGSVQFPTSSAVSSELGLDSLPTVDLEVMSVALRGVGDD-
MMAR_5383|M.marinum_M ELFDGYRFEIAGSVQFPTAAAVISELGLDTLPTVDLEVMSVALRGVGDD-
MAV_0198|M.avium_104 ELFDGYRFEIAGSVQFPTSQAVVDELGLDTIPTIDLDVMSVAVRGVGDD-
Mflv_1677|M.gilvum_PYR-GCK ELFDGFRFEIAGSVQVPTSAVVSDALELGDLPTVDLDVMSVQLRGVGDD-
MUL_2934|M.ulcerans_Agy99 ELIDGFHFEIAGSVQFPTASQISKELGLDTLPTVAPEVMSTNIGESDEE-
Mvan_0988|M.vanbaalenii_PYR-1 ELIDGFRYEIAGSVQFPTPAVVAKELGLDQLPTVDTEVMSVNLGDDGDE-
MAB_0948c|M.abscessus_ATCC_199 PAFEGVEARLS------RYSYLVSLMPRQIIDDLGLDVRLARRKYASYT-
TH_0456|M.thermoresistible__bu HAFDGVDARLS------RYSYLVSLLPRRIVDDLGARVRLARRRYSSYT-
MSMEG_0664|M.smegmatis_MC2_155 APWDDAPHLRVTRLSYVMSLMPPTIVRDLALERHGYKVHPMGPYYQAFPE
:. : : *
Mb3859c|M.bovis_AF2122/97 --PVVQFTDPTKMLTHLHRVHGADAVTGMAGLLAWSQAPTRALGRFEAGT
Rv3829c|M.tuberculosis_H37Rv --PVVQFTDPTKMLTHLHRVHGADAVTGMAGLLAWSQAPTRALGRFEAGT
MMAR_5383|M.marinum_M --PLVQYTDPMKMFAHLNEVHGADAVTGMAGLLAWSQAPTRALGRFESDT
MAV_0198|M.avium_104 --PLVQYSDPVKLFTHLNEVHGADAVNGMAGLMAWAQAPTRALDRFEAGT
Mflv_1677|M.gilvum_PYR-GCK --PLVYYTDPMKLLTHLNDVHGAEAVNGMAGLMAWCQAPTRALGRFEAAQ
MUL_2934|M.ulcerans_Agy99 --AMIFYRDPLQLISHLGEKHGSAAVTGMAELIGWSQGPARALGRFEVRT
Mvan_0988|M.vanbaalenii_PYR-1 --PMIFYRDPMQFMTHLAEKHGADAVAGMAGLLGWSHGPAQALGRFDVCT
MAB_0948c|M.abscessus_ATCC_199 --PDPMNGGQRGFLAGPND-------------FAEFGALCDSVTRPMWDS
TH_0456|M.thermoresistible__bu --PDPETGGRTGLLIGPETTFAAVGAADDEARFADFHRRSRMLTERLWPT
MSMEG_0664|M.smegmatis_MC2_155 GGSLTIYEDDPARTYEQLSRFSKKDADAWPKWNAWLEGIADVMGPLLTQV
. . . :
Mb3859c|M.bovis_AF2122/97 LPKS-------FDEMYACATN-EFERSAIDDMLFGSVTDVLDRHFPDREK
Rv3829c|M.tuberculosis_H37Rv LPKS-------FDEMYACATN-EFERSAIDDMLFGSVTDVLDRHFPDREK
MMAR_5383|M.marinum_M LPKT-------FDQMYACATN-EFERSAIDDMLFGSVTDVLDRYFPDREK
MAV_0198|M.avium_104 PPKS-------LDEMYACATN-EFERSAIDDMLFGSVTDILDRYLPDREK
Mflv_1677|M.gilvum_PYR-GCK PPKT-------LDEMFACATN-EFERQAISDILFGSVTDVLDRYLPDREK
MUL_2934|M.ulcerans_Agy99 PPRT-------LDEMYACATN-QAERRAIHEMLFGSAMDVIDRFLPDKEK
Mvan_0988|M.vanbaalenii_PYR-1 PPKT-------IDEMYACAAD-EDQRRAIHDVLFGTAMDAIDRYLPDRHR
MAB_0948c|M.abscessus_ATCC_199 MLQP-------LRRRGAVR----------TGAWEQLIETPIGEVIRAATP
TH_0456|M.thermoresistible__bu MLQP-------LRRRGDLRRQITAGAPDLDAVWRAMVDEPIGAAITAAVR
MSMEG_0664|M.smegmatis_MC2_155 PPNIGSHRPADLLDLAKLAWGQRGITSRAVADITRLLTMSIADLLDDWFE
. : : :
Mb3859c|M.bovis_AF2122/97 HGALRGSMTVLAVNTLYRGPATPGSAAALAFGLG--VPEGDFVRWKKLRG
Rv3829c|M.tuberculosis_H37Rv HGALRGSMTVLAVNTLYRGPATPGSAAALAFGLG--VPEGDFVRWKKLRG
MMAR_5383|M.marinum_M HAALRGSMTVLAVNTIYRGPATPGSAAALAFGLG--IPDGDFVQMKKLSG
MAV_0198|M.avium_104 HGALRGSMTVLAVNTLYRGPATPGSAAALAFGLG--VPDGDTMQMKKLRG
Mflv_1677|M.gilvum_PYR-GCK HGALRGMLAFLAVNTTYRGPATPGSAAALAFGLA--VPDENATLIKKFRG
MUL_2934|M.ulcerans_Agy99 HAVMRGILAFLAVNSTYRGPFTPGSAACLAFALA--VPDDSTAMMTKLRG
Mvan_0988|M.vanbaalenii_PYR-1 HAVLRSMLAFLAVNSTYRGPYTPGSATCLAFALA--VPDDSTAMMTKLQG
MAB_0948c|M.abscessus_ATCC_199 DDVRRGVLLTDALIGTFASADDLSLQQNICFLYH--QMN----PWDVPIG
TH_0456|M.thermoresistible__bu SDLVRGVIATDALIGTFARLDDPSLIQNRCFLYH--LIGG---DWAVPVG
MSMEG_0664|M.smegmatis_MC2_155 SPQIKGALAVNGVIGTWAGPYEPGTAYVMAHHSIGDVGDGQLGSWGFPEG
:. : .: : . .. *
Mb3859c|M.bovis_AF2122/97 GIGALTTHLSQLLERTGGEVRLRSKVTEIVVDNSRSSARVRGVRTAAGDT
Rv3829c|M.tuberculosis_H37Rv GIGALTTHLSQLLERTGGEVRLRSKVTEIVVDNSRSSARVRGVRTAAGDT
MMAR_5383|M.marinum_M GIGALTAHLCRLFERDGGELRLRTKVSEILVDSAEAGARISGVRTEAGDI
MAV_0198|M.avium_104 GIGALTSHLCDVLERHGGELRLRTKVTEILVEHAGSGGRVTGVRTESGET
Mflv_1677|M.gilvum_PYR-GCK GMGAVTEHLLQMFTAAGGELRLRTKVDEILVD----GGRVTGVRLEDGAT
MUL_2934|M.ulcerans_Agy99 GIGALTDHLRERFASAGGEIRFRSKVVEIVVD----RGAVSGVRLPDGSV
Mvan_0988|M.vanbaalenii_PYR-1 GIGALCDHLLDQYLRCGGAIRYRAKVDGITVD----GGRVTGVRLRDGSR
MAB_0948c|M.abscessus_ATCC_199 GMGAVTGSLEASARRHGAELLSGAEVLSISPD-----AEVRYRSDGGEHT
TH_0456|M.thermoresistible__bu GMGAVSGALAAAAAGFGAEILTGAQVSAITPD-----GEVRYHRDGADRW
MSMEG_0664|M.smegmatis_MC2_155 GMGAVSAAIACSARSFGAEIRTNARVSRLLVR----NGRVEGAVLDNGDE
*:**: : *. : :.* : . :
Mb3859c|M.bovis_AF2122/97 LTSPIVVSAIAPDVTINELIDPAVLPSEIRDRYLRIDHRGSYLQMHFALA
Rv3829c|M.tuberculosis_H37Rv LTSPIVVSAIAPDVTINELIDPAVLPSEIRDRYLRIDHRGSYLQMHFALA
MMAR_5383|M.marinum_M VAAPIVVSAIAPDVTINDLIDPTVLPSDVRDRYAHIDHRGSYLQMHFALE
MAV_0198|M.avium_104 LSAPIVVSGIAPDVTLNELLDPAALPADLRARYARIDHRGSYLQMHFALQ
Mflv_1677|M.gilvum_PYR-GCK LSAPVVVSNLAPDLTVNQLVDGSAIPADIRERFARIDHRGSYVQMHFALD
MUL_2934|M.ulcerans_Agy99 IGTPVVVSNLAPDVTLAKLVGPEHVPADLLARLAGRDHRASFVQIHFALD
Mvan_0988|M.vanbaalenii_PYR-1 IDAPAVISTLAPDLTLNTMVGAEHLPADLTARLTGRDHRASFVQIHFALD
MAB_0948c|M.abscessus_ATCC_199 VAGDRVLSGVSP-----------TVLAGLLGETPPAGQPGAQVKVNLLLR
TH_0456|M.thermoresistible__bu AHGEVVLANVAP-----------AELARLTGSAPPEVTPGAQVKVNLMLR
MSMEG_0664|M.smegmatis_MC2_155 IHAPVVVTTLHPKTAFLDHIPRTELPQDFVGDIEHWKSRSGVVKINLALA
*:: : * . .. ::::: *
Mb3859c|M.bovis_AF2122/97 QPPAFAAPYQALNDPSMQASMGIFCTPEQVQQQWEDCRRGIVPADPTVVL
Rv3829c|M.tuberculosis_H37Rv QPPAFAAPYQALNDPSMQASMGIFCTPEQVQQQWEDCRRGIVPADPTVVL
MMAR_5383|M.marinum_M EAPAFAAPYEALNDPAMQASIGIFCTPEEVQQQWEDCRRGIVPADPTVVL
MAV_0198|M.avium_104 EAPVFAAPYQVLNEPAMQASIGLFCTPEEVQQQWEQARRGVVPADPTVVL
Mflv_1677|M.gilvum_PYR-GCK GPPTFAEPYEVLNDPEYQSAIGIFTTPEELQQQWEDSRRGVVPADPAIAL
MUL_2934|M.ulcerans_Agy99 ALPEFAPPYELLNEPGMQQSVGIFGTPEEQQQQWETCRRGIVPENPSMGM
Mvan_0988|M.vanbaalenii_PYR-1 GLPEFAPPYDFLNEPGMQGSIGMFNSPEEQQRQWEECRRGVIPDNPSMGM
MAB_0948c|M.abscessus_ATCC_199 RLPRLRD-ENVTPEQAFGGTFHVNETYTQLEYAYQQASHGRIPDPLPCEI
TH_0456|M.thermoresistible__bu RLPRLRD-ETVTAEQAFGGTFHVNEGFGRLQAAYDEAAAGQVPAPLPCEV
MSMEG_0664|M.smegmatis_MC2_155 ELPNFTADPSSGIAEHHTGSVEMAPTMEFIEAAFQDARNGKPALLPFSDG
* : :. : : :: . * .
Mb3859c|M.bovis_AF2122/97 QIPSLHDP-----SLAPAGKQAASAFAMWFPIEGGSKY------GGYGRA
Rv3829c|M.tuberculosis_H37Rv QIPSLHDP-----SLAPAGKQAASAFAMWFPIEGGSKY------GGYGRA
MMAR_5383|M.marinum_M QVPSVHDP-----DLAPPGKHAASAFAMWFPIEGEQDS------HEYGQA
MAV_0198|M.avium_104 QIPSQNDP-----GLAPEGKHAASAFALWFPIEGEVD---------YGQA
Mflv_1677|M.gilvum_PYR-GCK QIPSANDP-----TLAPPGKHAVSAFSLWFPLSEEIS--------GYGAL
MUL_2934|M.ulcerans_Agy99 QIPSVHDS-----GLAPPGKHAASAYAYAFPVEVDRD--------QHGHL
Mvan_0988|M.vanbaalenii_PYR-1 QIPSVHDP-----AMAPPGMHAASAFAYAFPVETPRD--------QHGRL
MAB_0948c|M.abscessus_ATCC_199 YCHSLADPSILSPELRASGAHTLTVFGLHTPHGLGAS-----AEQLQQAV
TH_0456|M.thermoresistible__bu YAHSLTDPSILGDGLRAAGAHTMTVFGLHTPHRLAAADPDRVRDRLTSAV
MSMEG_0664|M.smegmatis_MC2_155 VIPTTLDT-----TLNPDGTHIMSLFTQWVPAEWAAEP--------HTEE
: *. : . * : : : *
Mb3859c|M.bovis_AF2122/97 KVEMGQNVIDKITRLAPNFKGSILRYTTFTPKHMGVMFGAPGGDYCHALL
Rv3829c|M.tuberculosis_H37Rv KVEMGQNVIDKITRLAPNFKGSILRYTTFTPKHMGVMFGAPGGDYCHALL
MMAR_5383|M.marinum_M KTEMGQRVIDKVTRLAPNFERSIIRHTTFTPKHMGVMFGAPGGDYCHGLL
MAV_0198|M.avium_104 KIEMGQRVIDKITRLAPNFEDSIIRHTTFTPRHMGVMFGAPGGDYCHGLL
Mflv_1677|M.gilvum_PYR-GCK KTEMGRRVIDKITRLATDFEKLILRHTTFTPKHMGTMFNAPGGDYCHGLI
MUL_2934|M.ulcerans_Agy99 KRIMARRVIDKITRFAPNFKDIVIRYITFAPYHMQTMFGAPSGDFCHGLL
Mvan_0988|M.vanbaalenii_PYR-1 KNVMAEKVIDKICRYAPNFRDVQIRHITFAPYHMDTMFAAPAGDFCHGLL
MAB_0948c|M.abscessus_ATCC_199 LASLSSVLAEPITDVVATDTHGRPCIETKTTIDLESALGMTAGNIFHGGL
TH_0456|M.thermoresistible__bu LTSLNSVLAEPIQDVIAEDAAGRLCIETKTTADLEHSLHMTAGNIFHGAL
MSMEG_0664|M.smegmatis_MC2_155 LDAYADRLIELYDQVAPGFKASITHRDIVGPYDMEHEYGLIGGNIFHGEL
: : . . .: .*: *. :
Mb3859c|M.bovis_AF2122/97 HSDQIGPNRP--GPKGFIGQPIPIAGLYLGSAGCHGGPGITFIPGYNAAR
Rv3829c|M.tuberculosis_H37Rv HSDQIGPNRP--GPKGFIGQPIPIAGLYLGSAGCHGGPGITFIPGYNAAR
MMAR_5383|M.marinum_M HPDQIGQNRP--GPRGFIGQPIPIAGLYLGSAGCHGGPGITFIPGFNAGR
MAV_0198|M.avium_104 NANQVGPNRP--GPRGFLGQPIPIEGLYLGSAGCHGGPGITFIPGYNAAR
Mflv_1677|M.gilvum_PYR-GCK HPEQMGPNRP--GPKGYVDQPIPIAGLYLAGAGCHGGPGITFIPGYNAAQ
MUL_2934|M.ulcerans_Agy99 HPDLMGPNRP--GPGGFLDFPIPIDGLYLGGAGCHGGPGITFIPGYNAAY
Mvan_0988|M.vanbaalenii_PYR-1 HPDLMGPNRP--GPKGFLDMPVPIDGLYLGGAGCHGGPGITFIPGYNAAH
MAB_0948c|M.abscessus_ATCC_199 QWPFAEDDDPLETAAQRWGVATNHDRILLCGSGSRRGGGVSGLGGYHAAR
TH_0456|M.thermoresistible__bu RWPFAEDDDPLDTPAQRWGVATGHDRILLCGSGSRRGGGVSGIGGHNAAM
MSMEG_0664|M.smegmatis_MC2_155 SLEQLFHMRP---APGYADYRTPIAGLYNGSSATHAGGGVCGIPGWQAAR
* . . : .:. : * *: : * :*.
Mb3859c|M.bovis_AF2122/97 QALADRRAANCCVLSGR----------
Rv3829c|M.tuberculosis_H37Rv QALADRRAANCCVLSGR----------
MMAR_5383|M.marinum_M AALADR---------------------
MAV_0198|M.avium_104 QALTDRSG-------------------
Mflv_1677|M.gilvum_PYR-GCK QVLAEH---------------------
MUL_2934|M.ulcerans_Agy99 QVLEDVATRQTSG--------------
Mvan_0988|M.vanbaalenii_PYR-1 QVLADRVSAASARTR------------
MAB_0948c|M.abscessus_ATCC_199 AVLETH---------------------
TH_0456|M.thermoresistible__bu AVLQR----------------------
MSMEG_0664|M.smegmatis_MC2_155 AVLADKKRARRSEALRKRLPAALGGRS
.*