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VSTIELSGITKTYGGSAVVDGLDLTLRDGTLTVLVGPSGCGKSTTLRIVAGLETADKGAVRIAGRDVTSA TPRERDVAMVFQNYALYPHLTVAGNVGFPLRNSGVAKTEVEQRVAQAAERVGITALLDRKPRQLSGGQQQ RVAIARALVRTPSAFLFDEPLSNLDAKLRVELRSEIRRLQTETGITSLYVTHDQEEAMTIADQLVVLDAG SIAQVGTPEELYRRPANTFVAGFIGSPSMNLVPGRLRAGRFEADGLTLVVAGDDRDDVTLGVRPEDLLVA PDPSGPGRVELVELLGPRYVLIIRAGAHRLTAVAEAATVSEWAGVPAAGDPVSVQARPGRTHLFDSTGAR I
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. smegmatis MC2 155 | MSMEG_0556 | - | - | 100% (351) | ABC transporter, nucleotide binding/ATPase protein |
| M. smegmatis MC2 155 | MSMEG_3108 | - | e-102 | 55.15% (359) | ABC transporter, ATPase subunit |
| M. smegmatis MC2 155 | MSMEG_0518 | - | 8e-86 | 46.57% (350) | sn-glycerol-3-phosphate ABC transporter ATPase |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb2856c | ugpC | 7e-81 | 52.98% (302) | sn-glycerol-3-phosphate transport ATP-binding protein ABC |
| M. gilvum PYR-GCK | Mflv_3778 | - | 1e-104 | 55.81% (353) | ABC transporter related |
| M. tuberculosis H37Rv | Rv2832c | ugpC | 7e-81 | 52.98% (302) | sn-glycerol-3-phosphate transport ATP-binding protein ABC |
| M. leprae Br4923 | MLBr_01424 | - | 3e-80 | 48.37% (337) | putative binding-protein-dependent transport protein |
| M. abscessus ATCC 19977 | MAB_1375 | - | 4e-81 | 46.83% (378) | sugar ABC transporter, ATP-binding protein SugC |
| M. marinum M | MMAR_1901 | - | 7e-82 | 47.91% (359) | ABC-type sugar transport protein, ATPase component |
| M. avium 104 | MAV_1377 | sugC | 2e-79 | 47.46% (354) | ABC transporter, ATP-binding protein SugC |
| M. thermoresistible (build 8) | TH_4034 | - | 5e-79 | 47.59% (353) | PUTATIVE ABC transporter, ATP-binding protein SugC |
| M. ulcerans Agy99 | MUL_2252 | - | 6e-80 | 46.37% (358) | sugar-transport ATP-binding protein ABC transporter |
| M. vanbaalenii PYR-1 | Mvan_2621 | - | 1e-105 | 56.70% (358) | ABC transporter-related protein |
CLUSTAL 2.0.9 multiple sequence alignment
MAV_1377|M.avium_104 MAEIVLDHVSKSYPDGAT----AVRDLNLTIADGEFLILVGPSGCGKTTT
TH_4034|M.thermoresistible__bu MAEIVLDKVTKSYPDGAGGVRHAVKDLSLTIADGEFIILVGPSGCGKSTT
MAB_1375|M.abscessus_ATCC_1997 MAEIVLNQVSKTYTDGSA----AVRDVSLNIADGEFIILVGPSGCGKSTT
Mb2856c|M.bovis_AF2122/97 MANVQYSAVTQRYPGADAP---TVDNLDLDIADGEFLVLVGPSGCGKSTT
Rv2832c|M.tuberculosis_H37Rv MANVQYSAVTQRYPGADAP---TVDNLDLDIADGEFLVLVGPSGCGKSTT
MMAR_1901|M.marinum_M MAKVQYSGVTYRYPGSGAP---AVNNLDLEIADGEFLVLVGPSGCGKSTI
MLBr_01424|M.leprae_Br4923 MASVTFEQATRQFPDTDRP---ALDRLDLDVDDGEFVVVVGPSGCGKTTS
MUL_2252|M.ulcerans_Agy99 MASVSFEGATRRYPGADRP---AVDSLDLVVDDGEFVVLVGPSGCGKTTS
Mflv_3778|M.gilvum_PYR-GCK MATVRFSGVTKAYGSTSV-----VSDLDLELPDGSLSVLVGPSGCGKSTT
Mvan_2621|M.vanbaalenii_PYR-1 MATVRFSGVNKAYGTTSV-----VSDLDLELPDGSFTVLVGPSGCGKSTS
MSMEG_0556|M.smegmatis_MC2_155 MSTIELSGITKTYGGSAV-----VDGLDLTLRDGTLTVLVGPSGCGKSTT
*: : . . : : :.* : ** : ::********:*
MAV_1377|M.avium_104 LNMIAGLEDISSGELRIGGERVNEKAPKDRDIAMVFQSYALYPHMTVRQN
TH_4034|M.thermoresistible__bu LNMIAGLEDITSGEIRIDGERVNEVAPKDRDIAMVFQSYALYPHMTVRQN
MAB_1375|M.abscessus_ATCC_1997 LNMIAGLEDISSGELTIAGERVNEKAPKDRDIAMVFQSYALYPHMTVRQN
Mb2856c|M.bovis_AF2122/97 LRVLAGLEPIESGRISIGDVDVTHLPPRARDVAMVFQNYALYPNMTVAAN
Rv2832c|M.tuberculosis_H37Rv LRVLAGLEPIESGRISIGDVDVTHLPPRARDVAMVFQNYALYPNMTVAAN
MMAR_1901|M.marinum_M LRVLAGLESVESGRITIGDTDVTDLPPRARDVAMVFQNYALYPNMTVAQN
MLBr_01424|M.leprae_Br4923 LRMVAGLETLDSGCIRIGDRDVTHVDPKDRDVAMVFQNYALYPHMTVAQN
MUL_2252|M.ulcerans_Agy99 LRMLAGLEKVDAGRIRIAERDVTNVDPKSRDVAMVFQNYALYPHMTVAQN
Mflv_3778|M.gilvum_PYR-GCK LRMLAGLETVTSGTITIGDRDVTHLQPRDRDIAMVFQNYALYPHLTVAEN
Mvan_2621|M.vanbaalenii_PYR-1 LRMLAGLETVTSGSITIGARDVTHLQPRDRDIAMVFQNYALYPHLTVAEN
MSMEG_0556|M.smegmatis_MC2_155 LRIVAGLETADKGAVRIAGRDVTSATPRERDVAMVFQNYALYPHLTVAGN
*.::**** * : * *. *: **:*****.*****::** *
MAV_1377|M.avium_104 IAFPLTLAKMKKPEIAQKVAETAKILDLTDFLDRKPSQLSGGQRQRVAMG
TH_4034|M.thermoresistible__bu IAFPLTLAKMKKADIARKVEETAKILDLTELLDRKPAQLSGGQRQRVAMG
MAB_1375|M.abscessus_ATCC_1997 IAFPLTLAKMSKDDINAKVAEAAKILDLTDYLDRKPANLSGGQRQRVAMG
Mb2856c|M.bovis_AF2122/97 MGFALRNAGMSRADTRRRVLEVADMLELTDLLDRKPAKLSGGQRQRVAMG
Rv2832c|M.tuberculosis_H37Rv MGFALRNAGMSRADTRRRVLEVADMLELTDLLDRKPAKLSGGQRQRVAMG
MMAR_1901|M.marinum_M MGFALRNAGMSRADTRQRVLEVASMLELTELLDRKPSKLSGGQRQRVAMG
MLBr_01424|M.leprae_Br4923 LGFALKISKISKAEIHDRILVVAKLLDLQPYLDRKPKDLSGGQRQRVAMG
MUL_2252|M.ulcerans_Agy99 MGFALKVAKTPKAEIRDRVLQAAKLLDLEAYLDRKPKDLSGGQRQRVAMG
Mflv_3778|M.gilvum_PYR-GCK IAFPLRANKTPRREALARAATVAESLGLSALLGRKPKDLSGGQQQRVAIG
Mvan_2621|M.vanbaalenii_PYR-1 IAFPLRATKTPRREALTRAATIAESLGLAKLLDRKPKDLSGGQQQRVAIG
MSMEG_0556|M.smegmatis_MC2_155 VGFPLRNSGVAKTEVEQRVAQAAERVGITALLDRKPRQLSGGQQQRVAIA
:.*.* : : : *. : : *.*** .*****:****:.
MAV_1377|M.avium_104 RAIVRHPKAFLMDEPLSNLDAKLRVQMRGEIARLQKRLGTTTVYVTHDQT
TH_4034|M.thermoresistible__bu RAIVRQPKAFLMDEPLSNLDAKLRVQMRSEIARLQSRLRTTTVYVTHDQT
MAB_1375|M.abscessus_ATCC_1997 RAIVRSPKAFLMDEPLSNLDAKLRVQMRTEIARLQKRLGTTTVYVTHDQT
Mb2856c|M.bovis_AF2122/97 RAIVRRPRVFCMDEPLSNLDAKLRVSTRSQISGLQRRLGTTTVYVTHDQV
Rv2832c|M.tuberculosis_H37Rv RAIVRRPRVFCMDEPLSNLDAKLRVSTRSQISGLQRRLGTTTVYVTHDQV
MMAR_1901|M.marinum_M RAIVRRPRVFCMDEPLSNLDAKLRVSTRSHISGLQRQLGTTTVYVTHDQV
MLBr_01424|M.leprae_Br4923 RAIVRRPQVFLMDEPLSNLDAKLRAQTRNQIAELQCQLGTTTVYVTHDQV
MUL_2252|M.ulcerans_Agy99 RAIVRRPQVFLMDEPLSNLDTKLRVQTRNQIAGLQRQLGTTTVYVTHDQV
Mflv_3778|M.gilvum_PYR-GCK RAIIREPSVFLFDEPLSNLDAKLRVETRTELAQIQRRLGITSVYVTHDQE
Mvan_2621|M.vanbaalenii_PYR-1 RAIIREPSVFLFDEPLSNLDAKLRVETRTELLQIQRRLGITSVYVTHDQE
MSMEG_0556|M.smegmatis_MC2_155 RALVRTPSAFLFDEPLSNLDAKLRVELRSEIRRLQTETGITSLYVTHDQE
**::* * .* :********:***.. * .: :* . *::******
MAV_1377|M.avium_104 EAMTLGDRVVVMHSGVAQQIGTPDELYENPANLFVAGFIGSPAMNFFPAT
TH_4034|M.thermoresistible__bu EAMTLGDRVVVMLDGVAQQIGTPDELYTQPANLFVAGFIGSPGMNFFPAS
MAB_1375|M.abscessus_ATCC_1997 EAMTLGDRVVVLRAGKVQQVGAPQELYDTPANLFVAGFIGSPSMNFFPAT
Mb2856c|M.bovis_AF2122/97 EAMTMGDRVAVLKDGVLQQVDTPRALYDDPVNTFVATFIGAPAMNLIDAA
Rv2832c|M.tuberculosis_H37Rv EAMTMGDRVAVLKDGVLQQVDTPRALYDDPVNTFVATFIGAPAMNLIDAA
MMAR_1901|M.marinum_M EAMTMGHRVAVLKDGVLQQVDTPRELYDNPVNTFVATFIGAPAMNLIEAP
MLBr_01424|M.leprae_Br4923 EAMTMGDRVAVLCYGVLQQFATPRELYHKPENVFVAGFIGSPGMNLVTLS
MUL_2252|M.ulcerans_Agy99 EAMTMGDRVAVLCDGVLQQCAAPRELYRRPDNVFVAGFIGSPAMNMFILP
Mflv_3778|M.gilvum_PYR-GCK EAMTLSDRMIVMRDGKIAQQGAPQDVYARPADTFVAAFVGSPKMNLLEGT
Mvan_2621|M.vanbaalenii_PYR-1 EAMTLSDRMVVMRDGRIAQQGTPQEVYARPADTFVAAFVGSPKMNLIDGA
MSMEG_0556|M.smegmatis_MC2_155 EAMTIADQLVVLDAGSIAQVGTPEELYRRPANTFVAGFIGSPSMNLVPGR
****:..:: *: * * :* :* * : *** *:*:* **:.
MAV_1377|M.avium_104 LTPIGLKVPFGEVMLTPEVQQVIAEHPEPDNVIVGARPEHLSDAALIDGY
TH_4034|M.thermoresistible__bu LTDAGVRLPFGEALLPPDVLDTVRRHEKTDNIIAGLRPEHLEDVSLLDTY
MAB_1375|M.abscessus_ATCC_1997 LTDVGVQLPFGEVTLDAGLYAGITARKPSGDVIVGIRPEQFEDAALVDTY
Mb2856c|M.bovis_AF2122/97 VAHGVVRAPDLAIPVP---------DPAAERVLVGVRPESWDVASIGT--
Rv2832c|M.tuberculosis_H37Rv VAHGVVRAPDLAIPVP---------DPAAERVLVGVRPESWDVASIGT--
MMAR_1901|M.marinum_M VADGVARLSGLVIPVP---------RGAADRVLIGVRPESWDVVGGDA--
MLBr_01424|M.leprae_Br4923 IVDSSVLLGDWPIRIPREI------ASAASEVIIGVRPEHFELGSLG---
MUL_2252|M.ulcerans_Agy99 IVDSSVLLGDWLIQLPREV------TVPAPEVVVGVRPEHFEVGNLG---
Mflv_3778|M.gilvum_PYR-GCK LTGGTFTLANGFALPIDE-------GATDGPLTLGVRPDDLLPTVGAADA
Mvan_2621|M.vanbaalenii_PYR-1 VSGTTFTVGDGFALTVDQ-------TAAGGPVTLGVRPDDLLPTVSDGDG
MSMEG_0556|M.smegmatis_MC2_155 LRAGRF-EADGLTLVVAG-------DDRD-DVTLGVRPEDLLVAP-DPSG
: : * **:
MAV_1377|M.avium_104 QRIRALTFEVKVDMVESLGADKYVYFSTAAWAAHSTQLDELAAEADAHEN
TH_4034|M.thermoresistible__bu ARLGAVTFDVNVELVESLGAEKYVHFRAEGAGAHAAQLAQLAAESGAGEN
MAB_1375|M.abscessus_ATCC_1997 KRITGLTLTVNADVVESLGSDKYVHFTTEGGAAHSDELTELAQESEVAEN
Mb2856c|M.bovis_AF2122/97 ----PGSLTVHVELVEELGFESFVYATPVDQRGWSSR-----------AP
Rv2832c|M.tuberculosis_H37Rv ----PGSLTVHVELVEELGFESFVYATPVDQRGWSSR-----------AP
MMAR_1901|M.marinum_M ----AAALGVRVEQVEELGFESFIYATPVAQDGWSSR-----------TR
MLBr_01424|M.leprae_Br4923 -------VEVEIDMVEELGADAYLYGRIAG--ASKVT-----------DQ
MUL_2252|M.ulcerans_Agy99 -------VEMEIDVVEELGADAYLYGRISN--GGTMI-----------DQ
Mflv_3778|M.gilvum_PYR-GCK P--------ARVALIEHLGPRAIVTVDARGTELTSVV-----------DT
Mvan_2621|M.vanbaalenii_PYR-1 A--------ARVILIEHLGPRAIVTIDARGTELTSVV-----------ET
MSMEG_0556|M.smegmatis_MC2_155 P--------GRVELVELLGPRYVLIIRAGAHRLTAVA-----------EA
. :* ** :
MAV_1377|M.avium_104 QFVARVPAESKAAIGQTVELALDTTKLMVFDADSGVNLTVAPSDSP
TH_4034|M.thermoresistible__bu EFIARVSTESKAKKGQSLQLAFNPAKLLVFDADTGANLTLPPSDA-
MAB_1375|M.abscessus_ATCC_1997 EFVARLSAASKVAEGQPIELIIDTGKLVIFDAESGENLSLAATAE-
Mb2856c|M.bovis_AF2122/97 RIVFRTDRRTAVRVGESLAIVPHSQEVRLFNSRTETRLR-------
Rv2832c|M.tuberculosis_H37Rv RIVFRTDRRTAVRVGESLAIVPHSQEVRLFNSRTETRLR-------
MMAR_1901|M.marinum_M RIVIRSDRHTTVGAGDSLSIAPNPQEVCFFDSRTESRIR-------
MLBr_01424|M.leprae_Br4923 LVVARVDGRNPPAKGSRVRLYTEPGNVHFFG-VDGHRIS-------
MUL_2252|M.ulcerans_Agy99 SVVARADGSNPPERGSRVRLYPQPAQLHFFT-VDGRRIA-------
Mflv_3778|M.gilvum_PYR-GCK ARLSGIT------EGTGVELAVRQGATHLFDTTTGRRIAGETR---
Mvan_2621|M.vanbaalenii_PYR-1 SRLSGIT------EGTPVDLAVRPGATHFFDPATGSRLSG------
MSMEG_0556|M.smegmatis_MC2_155 ATVSEWAG--VPAAGDPVSVQARPGRTHLFD-STGARI--------
: * : : .* .: