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MAAIRFEKAQLRYPHAPTPAVAELDLDIADGEFMVLVGPSGCGKSTTLRMLAGLEDLTSGSIYLDDRDIT TTPPQDRDIAMVFQNYALYPHMTVAGNMEFCLKNAGLSKDERRRRVAAAAETLGLTEYLNRKPKALSGGQ RQRVAMGRAIVRNPQVFCMDEPLSNLDAKMRVQTRTDIAKLQRELGVTTIYVTHDQTEAMTMGDRVGVMK DGVLQQVGAPMDLYDRPANAFVAGFIGSPAMKFFDAQLGDRTVGVAGHDMAVQCAADLRGPVLIGVRPEG WRLTAPDAGIAVKVGVVEVLGADSYLYGTAIHAGADVDVVVRVSTRDGIRADDTVHVTADPDAIHLFDNE TGVRLN
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. smegmatis MC2 155 | MSMEG_0508 | - | - | 100% (356) | glycerol-phosphate porter |
| M. smegmatis MC2 155 | MSMEG_5571 | - | 7e-98 | 54.12% (364) | ABC transporter ATP-binding protein |
| M. smegmatis MC2 155 | MSMEG_5058 | - | 6e-87 | 47.95% (390) | ABC transporter, ATP-binding protein SugC |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb2064c | - | 1e-106 | 57.71% (350) | sugar-transport ATP-binding protein ABC transporter |
| M. gilvum PYR-GCK | Mflv_3778 | - | 9e-91 | 50.56% (356) | ABC transporter related |
| M. tuberculosis H37Rv | Rv2038c | - | 1e-106 | 57.71% (350) | sugar-transport ATP-binding protein ABC transporter |
| M. leprae Br4923 | MLBr_01424 | - | 1e-100 | 54.86% (350) | putative binding-protein-dependent transport protein |
| M. abscessus ATCC 19977 | MAB_1375 | - | 9e-93 | 50.41% (367) | sugar ABC transporter, ATP-binding protein SugC |
| M. marinum M | MMAR_1901 | - | 1e-105 | 55.12% (361) | ABC-type sugar transport protein, ATPase component |
| M. avium 104 | MAV_2479 | - | 1e-103 | 56.57% (350) | glycerol-phosphate porter |
| M. thermoresistible (build 8) | TH_3215 | - | 1e-103 | 57.30% (363) | PUTATIVE ABC transporter ATP-binding protein |
| M. ulcerans Agy99 | MUL_2252 | - | 1e-102 | 57.10% (352) | sugar-transport ATP-binding protein ABC transporter |
| M. vanbaalenii PYR-1 | Mvan_2621 | - | 7e-92 | 50.98% (357) | ABC transporter-related protein |
CLUSTAL 2.0.9 multiple sequence alignment
Mb2064c|M.bovis_AF2122/97 --MASVSFEQATRRYPGTDRPALDRLDLIVGDGEFVVLVGPSGCGKTTSL
Rv2038c|M.tuberculosis_H37Rv --MASVSFEQATRRYPGTDRPALDRLDLIVGDGEFVVLVGPSGCGKTTSL
MUL_2252|M.ulcerans_Agy99 --MASVSFEGATRRYPGADRPAVDSLDLVVDDGEFVVLVGPSGCGKTTSL
MLBr_01424|M.leprae_Br4923 --MASVTFEQATRQFPDTDRPALDRLDLDVDDGEFVVVVGPSGCGKTTSL
MAV_2479|M.avium_104 MSMASVTFQQATRRYPGADRPALDNLNLVVGDGEFVVLVGPSGCGKTTSL
MMAR_1901|M.marinum_M --MAKVQYSGVTYRYPGSGAPAVNNLDLEIADGEFLVLVGPSGCGKSTIL
TH_3215|M.thermoresistible__bu --MATITYRNASCIYEGSDTFAVNSLNLEIEDGEFVVLVGPSGSGKSTAL
MSMEG_0508|M.smegmatis_MC2_155 --MAAIRFEKAQLRYPHAPTPAVAELDLDIADGEFMVLVGPSGCGKSTTL
MAB_1375|M.abscessus_ATCC_1997 --MAEIVLNQVSKTYTDG-SAAVRDVSLNIADGEFIILVGPSGCGKSTTL
Mflv_3778|M.gilvum_PYR-GCK --MATVRFSGVTKAYGST--SVVSDLDLELPDGSLSVLVGPSGCGKSTTL
Mvan_2621|M.vanbaalenii_PYR-1 --MATVRFSGVNKAYGTT--SVVSDLDLELPDGSFTVLVGPSGCGKSTSL
** : . : .: :.* : **.: ::*****.**:* *
Mb2064c|M.bovis_AF2122/97 RMVAGLETLDCGRIRIGERDVTEVDPKDRDVAMVFQNYALYPHMTVAQNM
Rv2038c|M.tuberculosis_H37Rv RMVAGLETLDCGRIRIGERDVTEVDPKDRDVAMVFQNYALYPHMTVAQNM
MUL_2252|M.ulcerans_Agy99 RMLAGLEKVDAGRIRIAERDVTNVDPKSRDVAMVFQNYALYPHMTVAQNM
MLBr_01424|M.leprae_Br4923 RMVAGLETLDSGCIRIGDRDVTHVDPKDRDVAMVFQNYALYPHMTVAQNL
MAV_2479|M.avium_104 RMVAGLETVDSGRILIGDRDVTNVDPKQRDVAMVFQNYALYPHMTVAQNM
MMAR_1901|M.marinum_M RVLAGLESVESGRITIGDTDVTDLPPRARDVAMVFQNYALYPNMTVAQNM
TH_3215|M.thermoresistible__bu RMLAGLEDIDDGDIEIGGRNMRGVPSKDRDIAMVFQNYALYPNKTVAENM
MSMEG_0508|M.smegmatis_MC2_155 RMLAGLEDLTSGSIYLDDRDITTTPPQDRDIAMVFQNYALYPHMTVAGNM
MAB_1375|M.abscessus_ATCC_1997 NMIAGLEDISSGELTIAGERVNEKAPKDRDIAMVFQSYALYPHMTVRQNI
Mflv_3778|M.gilvum_PYR-GCK RMLAGLETVTSGTITIGDRDVTHLQPRDRDIAMVFQNYALYPHLTVAENI
Mvan_2621|M.vanbaalenii_PYR-1 RMLAGLETVTSGSITIGARDVTHLQPRDRDIAMVFQNYALYPHLTVAENI
.::**** : * : : : .: **:*****.*****: ** *:
Mb2064c|M.bovis_AF2122/97 GFALKVAKIGKAEIRERVLAAAKLLDLQSYLDRKPKDLSGGQRQRVAMGR
Rv2038c|M.tuberculosis_H37Rv GFALKVAKIGKAEIRERVLAAAKLLDLQSYLDRKPKDLSGGQRQRVAMGR
MUL_2252|M.ulcerans_Agy99 GFALKVAKTPKAEIRDRVLQAAKLLDLEAYLDRKPKDLSGGQRQRVAMGR
MLBr_01424|M.leprae_Br4923 GFALKISKISKAEIHDRILVVAKLLDLQPYLDRKPKDLSGGQRQRVAMGR
MAV_2479|M.avium_104 GFAMKIAKTPKAQIRERVLDAAKLLDLQPYLDRKPKDLSGGQRQRVAMGR
MMAR_1901|M.marinum_M GFALRNAGMSRADTRQRVLEVASMLELTELLDRKPSKLSGGQRQRVAMGR
TH_3215|M.thermoresistible__bu GFALKLRGVAASERRRKVEEAAKLLDLTEFLDRKPAKLSGGQRQRVAMGR
MSMEG_0508|M.smegmatis_MC2_155 EFCLKNAGLSKDERRRRVAAAAETLGLTEYLNRKPKALSGGQRQRVAMGR
MAB_1375|M.abscessus_ATCC_1997 AFPLTLAKMSKDDINAKVAEAAKILDLTDYLDRKPANLSGGQRQRVAMGR
Mflv_3778|M.gilvum_PYR-GCK AFPLRANKTPRREALARAATVAESLGLSALLGRKPKDLSGGQQQRVAIGR
Mvan_2621|M.vanbaalenii_PYR-1 AFPLRATKTPRREALTRAATIAESLGLAKLLDRKPKDLSGGQQQRVAIGR
* : : : *. * * *.*** *****:****:**
Mb2064c|M.bovis_AF2122/97 AIVRRPQVFLMDEPLSNLDAKLRGQTRNQIAALQRQLGTTTVYVTHDQVE
Rv2038c|M.tuberculosis_H37Rv AIVRRPQVFLMDEPLSNLDAKLRGQTRNQIAALQRQLGTTTVYVTHDQVE
MUL_2252|M.ulcerans_Agy99 AIVRRPQVFLMDEPLSNLDTKLRVQTRNQIAGLQRQLGTTTVYVTHDQVE
MLBr_01424|M.leprae_Br4923 AIVRRPQVFLMDEPLSNLDAKLRAQTRNQIAELQCQLGTTTVYVTHDQVE
MAV_2479|M.avium_104 AIVRRPQVFLMDEPLSNLDAKLRVQTRNQIAALQRRLGTTTVYVTHDQVE
MMAR_1901|M.marinum_M AIVRRPRVFCMDEPLSNLDAKLRVSTRSHISGLQRQLGTTTVYVTHDQVE
TH_3215|M.thermoresistible__bu AIVREPQVFCMDEPLSNLDAKLRVQTRTQIAALQRRLGTTTVYVTHDQVE
MSMEG_0508|M.smegmatis_MC2_155 AIVRNPQVFCMDEPLSNLDAKMRVQTRTDIAKLQRELGVTTIYVTHDQTE
MAB_1375|M.abscessus_ATCC_1997 AIVRSPKAFLMDEPLSNLDAKLRVQMRTEIARLQKRLGTTTVYVTHDQTE
Mflv_3778|M.gilvum_PYR-GCK AIIREPSVFLFDEPLSNLDAKLRVETRTELAQIQRRLGITSVYVTHDQEE
Mvan_2621|M.vanbaalenii_PYR-1 AIIREPSVFLFDEPLSNLDAKLRVETRTELLQIQRRLGITSVYVTHDQEE
**:* * .* :********:*:* . *..: :* .** *::****** *
Mb2064c|M.bovis_AF2122/97 AMTMGDRVAVLSDGVLQQCASPRELYRNPGNVFVAGFIGSPAMNLFRLSI
Rv2038c|M.tuberculosis_H37Rv AMTMGDRVAVLSDGVLQQCASPRELYRNPGNVFVAGFIGSPAMNLFRLSI
MUL_2252|M.ulcerans_Agy99 AMTMGDRVAVLCDGVLQQCAAPRELYRRPDNVFVAGFIGSPAMNMFILPI
MLBr_01424|M.leprae_Br4923 AMTMGDRVAVLCYGVLQQFATPRELYHKPENVFVAGFIGSPGMNLVTLSI
MAV_2479|M.avium_104 AMTMGDRVAVLRDGVLQQFAPPRELYRNPSNVFVAGFIGSPAMNLFTLPV
MMAR_1901|M.marinum_M AMTMGHRVAVLKDGVLQQVDTPRELYDNPVNTFVATFIGAPAMNLIEAPV
TH_3215|M.thermoresistible__bu AMTMGDRVAVLKHGRLQQFASPGDLYHRPANAFVAGFIGSPAMNLFNAQL
MSMEG_0508|M.smegmatis_MC2_155 AMTMGDRVGVMKDGVLQQVGAPMDLYDRPANAFVAGFIGSPAMKFFDAQL
MAB_1375|M.abscessus_ATCC_1997 AMTLGDRVVVLRAGKVQQVGAPQELYDTPANLFVAGFIGSPSMNFFPATL
Mflv_3778|M.gilvum_PYR-GCK AMTLSDRMIVMRDGKIAQQGAPQDVYARPADTFVAAFVGSPKMNLLEGTL
Mvan_2621|M.vanbaalenii_PYR-1 AMTLSDRMVVMRDGRIAQQGTPQEVYARPADTFVAAFVGSPKMNLIDGAV
***:..*: *: * : * .* ::* * : *** *:*:* *::. :
Mb2064c|M.bovis_AF2122/97 ADSTVSLGDWQILLPRAVVGTAAE------VIIGVRPEHLELGG------
Rv2038c|M.tuberculosis_H37Rv ADSTVSLGDWQILLPRAVVGTAAE------VIIGVRPEHLELGG------
MUL_2252|M.ulcerans_Agy99 VDSSVLLGDWLIQLPREVTVPAPE------VVVGVRPEHFEVGN------
MLBr_01424|M.leprae_Br4923 VDSSVLLGDWPIRIPREIASAASE------VIIGVRPEHFELGS------
MAV_2479|M.avium_104 VDSAVSLGDWPIALPREIAAAASE------VVVGVRPEHFELGG------
MMAR_1901|M.marinum_M ADGVARLSGLVIPVPR---GAADR------VLIGVRPESWDVVGGDA---
TH_3215|M.thermoresistible__bu VPEGVQIGDTVLELERAQLTALHEAKLD-TVTVGLRPEHLELSD------
MSMEG_0508|M.smegmatis_MC2_155 GDRTVGVAGHDMAVQCAADLRGPV-------LIGVRPEGWRLTAP-----
MAB_1375|M.abscessus_ATCC_1997 TDVGVQLPFGEVTLDAGLYAGITARKPSGDVIVGIRPEQFEDAALVDTYK
Mflv_3778|M.gilvum_PYR-GCK TGGTFTLANG-FALPIDEGATDGP------LTLGVRPDDLLPTVG-----
Mvan_2621|M.vanbaalenii_PYR-1 SGTTFTVGDG-FALTVDQTAAGGP------VTLGVRPDDLLPTVS-----
: . : :*:**:
Mb2064c|M.bovis_AF2122/97 ----AGIEMDVDMVEELGADAYLYGRIVSGG-------------CEMDQS
Rv2038c|M.tuberculosis_H37Rv ----AGIEMDVDMVEELGADAYLYGRIVSGG-------------CEMDQS
MUL_2252|M.ulcerans_Agy99 ----LGVEMEIDVVEELGADAYLYGRISNGG-------------TMIDQS
MLBr_01424|M.leprae_Br4923 ----LGVEVEIDMVEELGADAYLYGRIAGAS-------------KVTDQL
MAV_2479|M.avium_104 ----LGVEMEVDVVEELGADAYLYGRITGSG-------------KVIDAP
MMAR_1901|M.marinum_M ---AAALGVRVEQVEELGFESFIYATPVAQDGW-----------SSRTRR
TH_3215|M.thermoresistible__bu ---AGGVEVVVDLVEDLGSEAYLYTHTGSG------------------VD
MSMEG_0508|M.smegmatis_MC2_155 ---DAGIAVKVGVVEVLGADSYLYGTAIHAG---------------ADVD
MAB_1375|M.abscessus_ATCC_1997 RITGLTLTVNADVVESLGSDKYVHFTTEGGAAHSDELTELAQESEVAENE
Mflv_3778|M.gilvum_PYR-GCK ---AADAPARVALIEHLGPRAIVTVDARGTE-----------------LT
Mvan_2621|M.vanbaalenii_PYR-1 ---DGDGAARVILIEHLGPRAIVTIDARGTE-----------------LT
:* ** :
Mb2064c|M.bovis_AF2122/97 IVARVDGRGPPERGSRVRLCP-TPGHLHFFA-VDGRRIPG-----
Rv2038c|M.tuberculosis_H37Rv IVARVDGRGPPERGSRVRLCP-TPGHLHFFA-VDGRRIPG-----
MUL_2252|M.ulcerans_Agy99 VVARADGSNPPERGSRVRLYP-QPAQLHFFT-VDGRRIA------
MLBr_01424|M.leprae_Br4923 VVARVDGRNPPAKGSRVRLYT-EPGNVHFFG-VDGHRIS------
MAV_2479|M.avium_104 IVARVDGRNPPEKGSRVRLHP-APGHLHFFG-RNGQRIGVRGSW-
MMAR_1901|M.marinum_M IVIRSDRHTTVGAGDSLSIAP-NPQEVCFFDSRTESRIR------
TH_3215|M.thermoresistible__bu LVARCLDRVPAKLADTVRLRKRTDGVVHLFHPDTGERVGE-----
MSMEG_0508|M.smegmatis_MC2_155 VVVRVSTRDGIRADDTVHVTA-DPDAIHLFDNETGVRLN------
MAB_1375|M.abscessus_ATCC_1997 FVARLSAASKVAEGQPIELII-DTGKLVIFDAESGENLSLAATAE
Mflv_3778|M.gilvum_PYR-GCK SVVDTARLSGITEGTGVELAV-RQGATHLFDTTTGRRIAGETR--
Mvan_2621|M.vanbaalenii_PYR-1 SVVETSRLSGITEGTPVDLAV-RPGATHFFDPATGSRLSG-----
* : : :* .: