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EVVGIDKEYPAATGPIQILRGLSLRADRGEFVSIVGPSGCGKSTLFNIITGLVPPTAGSVLVNGEDVTGS TSRHIGYVLQKDLLFPWRTVLENVVLGLEVRGVRKKDARTRARSLFATYKLEGYEDKYPSDLSGGMKQRA ALMRTMVTDPDIILMDEAYKALDYPLKIALESELLETARTTGKTVVAVTHDIEEAVTMSDRVYVLKARPG EVVSEFPIDLGTTSTDINERRLAPRFNEFYEKIWRGIGQKPGAA*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. smegmatis MC2 155 | MSMEG_0488 | - | - | 100% (255) | ABC transporter ATP-binding protein |
| M. smegmatis MC2 155 | MSMEG_2459 | - | 2e-49 | 41.94% (248) | transporter ATPase |
| M. smegmatis MC2 155 | MSMEG_2502 | - | 9e-49 | 43.80% (242) | transporter ATPase |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb2419c | cysA1 | 8e-32 | 39.11% (179) | sulfate-transport ATP-binding protein ABC transporter CysA1 |
| M. gilvum PYR-GCK | Mflv_0722 | - | 1e-35 | 32.79% (244) | ABC transporter related |
| M. tuberculosis H37Rv | Rv2397c | cysA1 | 9e-32 | 39.11% (179) | sulfate-transport ATP-binding protein ABC transporter CysA1 |
| M. leprae Br4923 | MLBr_01424 | - | 2e-31 | 37.31% (201) | putative binding-protein-dependent transport protein |
| M. abscessus ATCC 19977 | MAB_2178 | - | 3e-37 | 33.73% (249) | ABC transporter ATP-binding protein |
| M. marinum M | MMAR_3011 | - | 4e-34 | 40.20% (204) | sugar-transport ATP-binding protein ABC transporter |
| M. avium 104 | MAV_3398 | - | 2e-36 | 40.58% (207) | ABC transporter ATP-binding protein |
| M. thermoresistible (build 8) | TH_4520 | - | 1e-35 | 35.81% (229) | PUTATIVE osmoprotectant (glycine |
| M. ulcerans Agy99 | MUL_2252 | - | 4e-34 | 40.20% (204) | sugar-transport ATP-binding protein ABC transporter |
| M. vanbaalenii PYR-1 | Mvan_0123 | - | 1e-37 | 33.06% (248) | ABC transporter-related protein |
CLUSTAL 2.0.9 multiple sequence alignment
Mflv_0722|M.gilvum_PYR-GCK MSSQSDTEPVAPQRRSGAIQIRSVSHRYGQGRDEVTALGPVDLTVEPGSF
Mvan_0123|M.vanbaalenii_PYR-1 MPSTND----------GAIRIDSVSHHYGSGGAEVTALGPVDLTVDPGSF
MAB_2178|M.abscessus_ATCC_1997 MPLVDEAETAVQERDTGSIRISGVTHSYGSGAGKTTALGPVDLTVEPGTF
MAV_3398|M.avium_104 MT-------------AMRLELDRVRLSYN-GPAVINELS---LVVRPGEI
TH_4520|M.thermoresistible__bu ---VSEPTSDLQSGGGARILLDGVTKRYD--PKSPPAVDNITMEIPAGEI
Mb2419c|M.bovis_AF2122/97 --------------MTYAIVVADATKRYG----DFVALDHVDFVVPTGSL
Rv2397c|M.tuberculosis_H37Rv --------------MTYAIVVADATKRYG----DFVALDHVDFVVPTGSL
MSMEG_0488|M.smegmatis_MC2_155 ------------------MEVVGIDKEYPAATGPIQILRGLSLRADRGEF
MMAR_3011|M.marinum_M ---------------MASVSFEGATRRYP--GADRPAVDSLDLEVDDGEF
MUL_2252|M.ulcerans_Agy99 ---------------MASVSFEGATRRYP--GADRPAVDSLDLVVDDGEF
MLBr_01424|M.leprae_Br4923 ---------------MASVTFEQATRQFP--DTDRPALDRLDLDVDDGEF
: . : : : * :
Mflv_0722|M.gilvum_PYR-GCK LVLVGASGCGKSTLLRLLAGFESPTDGSVDVEGVPPTPGVTAG------V
Mvan_0123|M.vanbaalenii_PYR-1 LVLVGASGCGKSTLLRLLAGFEEPSQGSVQVAGARPTPGVTAG------V
MAB_2178|M.abscessus_ATCC_1997 LVLVGASGCGKSTLLRLLAGFESPSEGAVRVAGGVPTPGITSG------V
MAV_3398|M.avium_104 LVLTGPSGCGKSTVLRALAGLLTPDGGRVLADG-VPVTGTSGDR----AM
TH_4520|M.thermoresistible__bu VMLVGPSGCGKTTTMKMINRLIEPTSGRIFIGDDDVTERDADELRRHIGY
Mb2419c|M.bovis_AF2122/97 TALLGPSGSGKSTLLRTIAGLDQPDTGTITINGRDVTRVPPQRRG--IGF
Rv2397c|M.tuberculosis_H37Rv TALLGPSGSGKSTLLRTIAGLDQPDTGTITINGRDVTRVPPQRRG--IGF
MSMEG_0488|M.smegmatis_MC2_155 VSIVGPSGCGKSTLFNIITGLVPPTAGSVLVNGEDVTGSTSRHIG----Y
MMAR_3011|M.marinum_M VVLVGPSGCGKTTSLRMLAGLERVDAGRIRIAERDVTNVDPKSRD--VAM
MUL_2252|M.ulcerans_Agy99 VVLVGPSGCGKTTSLRMLAGLEKVDAGRIRIAERDVTNVDPKSRD--VAM
MLBr_01424|M.leprae_Br4923 VVVVGPSGCGKTTSLRMVAGLETLDSGCIRIGDRDVTHVDPKDRD--VAM
: *.**.**:* :. : : * : . .
Mflv_0722|M.gilvum_PYR-GCK VFQQPRLFPWRTVGGNVELALKYAKVPRDKRSERRDELLERVGLGG--TA
Mvan_0123|M.vanbaalenii_PYR-1 VFQQPRLFPWRTVGGNVDMALRYAKVPRDKRIERREELLGRVGLEG--TA
MAB_2178|M.abscessus_ATCC_1997 VFQQPRLFPWRTVGGNIELALKYAKVPRERWAQRRDQLLARVGLEG--TA
MAV_3398|M.avium_104 VFQDNALLPWRTVRSNIELALRLRGQPRAGRRAAAERWISELGLAG--FG
TH_4520|M.thermoresistible__bu VIQGAGLFPHYTVAENIAIVPRLLKWDRKRIAARVDELLDLVSLDPDEYR
Mb2419c|M.bovis_AF2122/97 VFQHYAAFKHLTVRDNVAFGLKIRKRPKAEIKAKVDNLLQVVGLSG--FQ
Rv2397c|M.tuberculosis_H37Rv VFQHYAAFKHLTVRDNVAFGLKIRKRPKAEIKAKVDNLLQVVGLSG--FQ
MSMEG_0488|M.smegmatis_MC2_155 VLQKDLLFPWRTVLENVVLGLEVRGVRKKDARTRARSLFATYKLEG--YE
MMAR_3011|M.marinum_M VFQNYALYPHMTVAQNMGFALKVAKTPKAEIRDRVLQAAKLLDLEA--YL
MUL_2252|M.ulcerans_Agy99 VFQNYALYPHMTVAQNMGFALKVAKTPKAEIRDRVLQAAKLLDLEA--YL
MLBr_01424|M.leprae_Br4923 VFQNYALYPHMTVAQNLGFALKISKISKAEIHDRILVVAKLLDLQP--YL
*:* ** *: : . : *
Mflv_0722|M.gilvum_PYR-GCK GRRIWEISGGQQQRVAIARALAAETPLFLLDEPFAALDALTRERLQEDVR
Mvan_0123|M.vanbaalenii_PYR-1 DRRIWEISGGQQQRVAIARALAAETPLFLLDEPFAALDALTRERLQEDVR
MAB_2178|M.abscessus_ATCC_1997 GRRIWEISGGQQQRVAIARALAAETPLFLLDEPFAALDALTRERLQEDVR
MAV_3398|M.avium_104 DYLPKSLSGGMRQRVQLARGLAGAPRAVMMDEPFGALDTRTRAAMQRLLI
TH_4520|M.thermoresistible__bu DRYPRELSGGQQQRVGVARALAADPPVLLMDEPFGAVDPITRQRLQDELL
Mb2419c|M.bovis_AF2122/97 SRYPNQLSGGQRQRMALARALAVDPEVLLLDEPFGALDAKVREELRAWLR
Rv2397c|M.tuberculosis_H37Rv SRYPNQLSGGQRQRMALARALAVDPEVLLLDEPFGALDAKVREELRAWLR
MSMEG_0488|M.smegmatis_MC2_155 DKYPSDLSGGMKQRAALMRTMVTDPDIILMDEAYKALDYPLKIALESELL
MMAR_3011|M.marinum_M DRKPKDLSGGQRQRVAMGRAIVRRPQVFLMDEPLSNLDAKLRVQTRNQIA
MUL_2252|M.ulcerans_Agy99 DRKPKDLSGGQRQRVAMGRAIVRRPQVFLMDEPLSNLDTKLRVQTRNQIA
MLBr_01424|M.leprae_Br4923 DRKPKDLSGGQRQRVAMGRAIVRRPQVFLMDEPLSNLDAKLRAQTRNQIA
. .:*** :** : * :. . .::**. :* : . :
Mflv_0722|M.gilvum_PYR-GCK QVSAESGRTTVFVTHSADEAAFLGSRIVVLTRRPGQIALDIPVDLPRTGV
Mvan_0123|M.vanbaalenii_PYR-1 QVSAESGRTTVFVTHSADEAAFLGSRIVVLTRRPGQVALDIPVDLPRTGV
MAB_2178|M.abscessus_ATCC_1997 QVSAESGRTTVFVTHSADEAAFLGSRIVVLTRRPGQVALDIPVDLPRTGI
MAV_3398|M.avium_104 DTWRTHPTTIVFVTHDVDEALALGDRIVVLG-RAG--------EPPRASV
TH_4520|M.thermoresistible__bu RLQDELRKTIVFVTHDFDEAVKLGDRIAILQQGSKVVQYDTPEEILTNPA
Mb2419c|M.bovis_AF2122/97 RLHDEVHVTTVLVTHDQAEALDVADRIAVLH-KGRIEQVGSPTDVYDAPA
Rv2397c|M.tuberculosis_H37Rv RLHDEVHVTTVLVTHDQAEALDVADRIAVLH-KGRIEQVGSPTDVYDAPA
MSMEG_0488|M.smegmatis_MC2_155 ETARTTGKTVVAVTHDIEEAVTMSDRVYVLKARPGEVVSEFPIDLGTTST
MMAR_3011|M.marinum_M GLQRQLGTTTVYVTHDQVEAMTMGDRVAVLC-DGVLQQCAAPRELYRRPD
MUL_2252|M.ulcerans_Agy99 GLQRQLGTTTVYVTHDQVEAMTMGDRVAVLC-DGVLQQCAAPRELYRRPD
MLBr_01424|M.leprae_Br4923 ELQCQLGTTTVYVTHDQVEAMTMGDRVAVLC-YGVLQQFATPRELYHKPE
* * ***. ** :..*: :* :
Mflv_0722|M.gilvum_PYR-GCK D-----------------PEELRRSPEYGELRAEVG----AAVRRAAA--
Mvan_0123|M.vanbaalenii_PYR-1 D-----------------PDELRRSPEYGQLRAEVG----RAVKAAAA--
MAB_2178|M.abscessus_ATCC_1997 D-----------------PDDLRRSPEYAQLRTEVG----RAVKAAAA--
MAV_3398|M.avium_104 E-----------------VPEPRSDRPHAELRAQII----DALNHAEAA-
TH_4520|M.thermoresistible__bu DDFVKGFVGHGAALKQLTLTRVRDVDLHDAVTARAGGDPDEAIHAARAAD
Mb2419c|M.bovis_AF2122/97 NAFVMSFLG---------AVSTLNGSLVRPHDIRVGRTPNMAVAAADGTA
Rv2397c|M.tuberculosis_H37Rv NAFVMSFLG---------AVSTLNGSLVRPHDIRVGRTPNMAVAAADGTA
MSMEG_0488|M.smegmatis_MC2_155 D-----------------INERRLAPRFNEFYEKIWRGIGQKPGAA----
MMAR_3011|M.marinum_M NVFVAGFIGSPAMN-MFILPIVDSSVLLGDWLIQLPREVTVPAPEVVVGV
MUL_2252|M.ulcerans_Agy99 NVFVAGFIGSPAMN-MFILPIVDSSVLLGDWLIQLPREVTVPAPEVVVGV
MLBr_01424|M.leprae_Br4923 NVFVAGFIGSPGMN-LVTLSIVDSSVLLGDWPIRIPREIASAASEVIIGV
: . .
Mflv_0722|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_0123|M.vanbaalenii_PYR-1 --------------------------------------------------
MAB_2178|M.abscessus_ATCC_1997 --------------------------------------------------
MAV_3398|M.avium_104 --------------------------------------------------
TH_4520|M.thermoresistible__bu REHVIVLDAQNRPMRWMSLAELARPGALIRVSRDENLECVTLASTLTDAL
Mb2419c|M.bovis_AF2122/97 GSTGVLRAVVDRVVVLGFEVRVELTSAATGGAFTAQITRGDAEALALREG
Rv2397c|M.tuberculosis_H37Rv GSTGVLRAVVDRVVVLGFEVRVELTSAATGGAFTAQITRGDAEALALREG
MSMEG_0488|M.smegmatis_MC2_155 --------------------------------------------------
MMAR_3011|M.marinum_M RPEHFEVGNLGVEMEIDVVEELGADAYLYGRIINGGAMIDQSVVARADGS
MUL_2252|M.ulcerans_Agy99 RPEHFEVGNLGVEMEIDVVEELGADAYLYGRISNGGTMIDQSVVARADGS
MLBr_01424|M.leprae_Br4923 RPEHFELGSLGVEVEIDMVEELGADAYLYGRIAGASKVTDQLVVARVDGR
Mflv_0722|M.gilvum_PYR-GCK ------------------------------------------------
Mvan_0123|M.vanbaalenii_PYR-1 ------------------------------------------------
MAB_2178|M.abscessus_ATCC_1997 ------------------------------------------------
MAV_3398|M.avium_104 ------------------------------------------------
TH_4520|M.thermoresistible__bu DDMLTSSHGVVVVTGRRNTYQGVIRLETIMDAIADARGTAGSQGAGAP
Mb2419c|M.bovis_AF2122/97 DTVYVRATRVPPIAGGVSGVDDAGVERVKVTST---------------
Rv2397c|M.tuberculosis_H37Rv DTVYVRATRVPPIAGGVSGVDDAGVERVKVTST---------------
MSMEG_0488|M.smegmatis_MC2_155 ------------------------------------------------
MMAR_3011|M.marinum_M NPPERGSRVRLYPQPAQLHFFTVDGRRIA-------------------
MUL_2252|M.ulcerans_Agy99 NPPERGSRVRLYPQPAQLHFFTVDGRRIA-------------------
MLBr_01424|M.leprae_Br4923 NPPAKGSRVRLYTEPGNVHFFGVDGHRIS-------------------