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TDQRSVRPIVEVSGCVQRFGGLHALGPIDLTIRSGEFVSIVGPSGCGKSTLLELVAGLQVPADGRVSVAG EPLRGPRDRTAIAFQESATLPWRTVRDNVAFALEVRAVPKAERRRRADELIRTVGLAGFEDNYPSQLSGG MRQRVAIARCLSMDPDLILADEPFGALDEQTRLLMSFELMRVVEELSCGVLFITHSIQEAVLLSDRVLVM SARPGTILDEIHVDLPRPRDEHTLASPRMAALTERIWAQLKDEAGKAMEATLR*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. smegmatis MC2 155 | MSMEG_2502 | - | - | 100% (264) | transporter ATPase |
| M. smegmatis MC2 155 | MSMEG_2459 | - | 3e-67 | 52.34% (235) | transporter ATPase |
| M. smegmatis MC2 155 | MSMEG_1160 | - | 2e-56 | 44.49% (254) | ABC-type nitrate/sulfonate/bicarbonate transport system ATPase |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb2419c | cysA1 | 7e-43 | 42.65% (204) | sulfate-transport ATP-binding protein ABC transporter CysA1 |
| M. gilvum PYR-GCK | Mflv_0722 | - | 2e-46 | 43.78% (233) | ABC transporter related |
| M. tuberculosis H37Rv | Rv2397c | cysA1 | 7e-43 | 42.65% (204) | sulfate-transport ATP-binding protein ABC transporter CysA1 |
| M. leprae Br4923 | MLBr_01089 | - | 5e-35 | 39.38% (193) | putative ABC-transport protein, ATP-binding component |
| M. abscessus ATCC 19977 | MAB_2178 | - | 1e-45 | 40.08% (257) | ABC transporter ATP-binding protein |
| M. marinum M | MMAR_3715 | cysA1 | 1e-41 | 41.75% (206) | sulfate-transport ATP-binding protein ABC transporter CysA1 |
| M. avium 104 | MAV_3398 | - | 5e-45 | 43.18% (220) | ABC transporter ATP-binding protein |
| M. thermoresistible (build 8) | TH_2424 | - | 9e-43 | 42.93% (205) | PUTATIVE sulfate ABC transporter, ATPase subunit |
| M. ulcerans Agy99 | MUL_3658 | cysA1 | 1e-41 | 41.75% (206) | sulfate-transport ATP-binding protein ABC transporter CysA1 |
| M. vanbaalenii PYR-1 | Mvan_3141 | - | 7e-51 | 44.87% (234) | ABC transporter-related protein |
CLUSTAL 2.0.9 multiple sequence alignment
Mb2419c|M.bovis_AF2122/97 --------MT------YAIVVADATKRYGD----FVALDHVDFVVPTGSL
Rv2397c|M.tuberculosis_H37Rv --------MT------YAIVVADATKRYGD----FVALDHVDFVVPTGSL
MMAR_3715|M.marinum_M --MKKETSLTGPGTGGHAIVVRDAFKQYGD----FVALDHVDFVVPAGSL
MUL_3658|M.ulcerans_Agy99 --------MTGPGTGGHAIVVRDAFKQYGD----FVALDHVDFVVPAGSL
TH_2424|M.thermoresistible__bu --------MT------DAITVRGANKRYGD----FAALDNVDFAVPAGSL
MSMEG_2502|M.smegmatis_MC2_155 MTDQRSVRPIVE--------VSGCVQRFGG----LHALGPIDLTIRSGEF
Mvan_3141|M.vanbaalenii_PYR-1 MS-----------------------RTFGA----VDALAPCDLAVKRGEF
Mflv_0722|M.gilvum_PYR-GCK MSSQSDTEPVAPQRRSGAIQIRSVSHRYGQGRDEVTALGPVDLTVEPGSF
MAB_2178|M.abscessus_ATCC_1997 MPLVDEAETAVQERDTGSIRISGVTHSYGSGAGKTTALGPVDLTVEPGTF
MAV_3398|M.avium_104 MTAMRLELDRVR-------------LSYNG----PAVINELSLVVRPGEI
MLBr_01089|M.leprae_Br4923 ---------------MAEIVLEHVNKNYPNG---ATAVHDLSITVADGEF
: .: .:.: * :
Mb2419c|M.bovis_AF2122/97 TALLGPSGSGKSTLLRTIAGLDQPDTGTITINGRDVTRVPPQRRGIGFVF
Rv2397c|M.tuberculosis_H37Rv TALLGPSGSGKSTLLRTIAGLDQPDTGTITINGRDVTRVPPQRRGIGFVF
MMAR_3715|M.marinum_M TALLGPSGSGKSTLLRTIAGLDQPDSGNITINGRDVTRVPPQRRGIGFVF
MUL_3658|M.ulcerans_Agy99 TALLGPSGSGKSTLLRTIAGLDQPDSGNITINGRDVTRVPPQRRGIGFVF
TH_2424|M.thermoresistible__bu TALLGPSGSGKSTLLRAIAGLDRPDTGTITINGRDVTDVPPQRRGIGFVF
MSMEG_2502|M.smegmatis_MC2_155 VSIVGPSGCGKSTLLELVAGLQVPADGRVSVAGE---PLRGPRDRTAIAF
Mvan_3141|M.vanbaalenii_PYR-1 ISIIGPSGCGKSTLLRLASKLDEPTAGAVEFA----------TDSVGYVF
Mflv_0722|M.gilvum_PYR-GCK LVLVGASGCGKSTLLRLLAGFESPTDGSVDVEG----VPPTPGVTAGVVF
MAB_2178|M.abscessus_ATCC_1997 LVLVGASGCGKSTLLRLLAGFESPSEGAVRVAG----GVPTPGITSGVVF
MAV_3398|M.avium_104 LVLTGPSGCGKSTVLRALAGLLTPDGGRVLADGV---PVTGTSGDRAMVF
MLBr_01089|M.leprae_Br4923 LILIGPSGCGKTTTLNMIAGLEDISSGELRIDGDRVNEKAPKDRDIAMVF
: *.**.**:* *. : : * : . .*
Mb2419c|M.bovis_AF2122/97 QHYAAFKHLTVRDNVAFGLKIRKRPKAEIKAKVDNLLQVVGLSGFQSRYP
Rv2397c|M.tuberculosis_H37Rv QHYAAFKHLTVRDNVAFGLKIRKRPKAEIKAKVDNLLQVVGLSGFQSRYP
MMAR_3715|M.marinum_M QHYAAFKHLTVRDNVAYGLKIRKRPKAEIRDKVDNLLEVVGLSGFHGRYP
MUL_3658|M.ulcerans_Agy99 QHYAAFKHLTVRDNVAYGLKIRKRPKAEIRDKVDNLLEVVGLSGFHGRYP
TH_2424|M.thermoresistible__bu QHYAAFKHLTVRDNVAFGLKIRRRPKREIAEKVDNLLEVVGLAGFQNRYP
MSMEG_2502|M.smegmatis_MC2_155 QESATLPWRTVRDNVAFALEVRAVPKAERRRRADELIRTVGLAGFEDNYP
Mvan_3141|M.vanbaalenii_PYR-1 QDATLMPWRTVRRNVGLLAELQGRGRAEIRSEVESALATVGLTDFAEHLP
Mflv_0722|M.gilvum_PYR-GCK QQPRLFPWRTVGGNVELALKYAKVPRDKRSERRDELLERVGLGGTAGRRI
MAB_2178|M.abscessus_ATCC_1997 QQPRLFPWRTVGGNIELALKYAKVPRERWAQRRDQLLARVGLEGTAGRRI
MAV_3398|M.avium_104 QDNALLPWRTVRSNIELALRLRGQPRAGRRAAAERWISELGLAGFGDYLP
MLBr_01089|M.leprae_Br4923 QSYALYPHMTVRQNIAFPLMLAKVKKAEIAQKVSETAQILDLTDLLDRKP
* ** *: : . :.* .
Mb2419c|M.bovis_AF2122/97 NQLSGGQRQRMALARALAVDPEVLLLDEPFGALDAKVREELRAWLRRLHD
Rv2397c|M.tuberculosis_H37Rv NQLSGGQRQRMALARALAVDPEVLLLDEPFGALDAKVREELRAWLRRLHD
MMAR_3715|M.marinum_M NQLSGGQRQRMALARALAVDPEVLLLDEPFGALDAKVREDLRAWLRRLHD
MUL_3658|M.ulcerans_Agy99 DQLSGGQRQRMALARALAVDPEVLLLDEPFGALDAKVREDLRAWLRRLHD
TH_2424|M.thermoresistible__bu NQLSGGQRQRMALARALAVDPEVLLLDEPFGALDAKVREDLRTWLRRLHE
MSMEG_2502|M.smegmatis_MC2_155 SQLSGGMRQRVAIARCLSMDPDLILADEPFGALDEQTRLLMSFELMRVVE
Mvan_3141|M.vanbaalenii_PYR-1 RQLSGGMKMRASLARSLVLKPEVFLFDEPFGALDEITRGRLNLVLQDLFL
Mflv_0722|M.gilvum_PYR-GCK WEISGGQQQRVAIARALAAETPLFLLDEPFAALDALTRERLQEDVRQVSA
MAB_2178|M.abscessus_ATCC_1997 WEISGGQQQRVAIARALAAETPLFLLDEPFAALDALTRERLQEDVRQVSA
MAV_3398|M.avium_104 KSLSGGMRQRVQLARGLAGAPRAVMMDEPFGALDTRTRAAMQRLLIDTWR
MLBr_01089|M.leprae_Br4923 SQLSGGQRQRVAMGRAIVRHPKAFLMDEPLSNLDAKLRVRTRGEIARLQR
.:*** : * :.* : . .: ***:. ** * :
Mb2419c|M.bovis_AF2122/97 EVHVTTVLVTHDQAEALDVADRIAVLHKGRIEQVGSPTDVYDAPANAFVM
Rv2397c|M.tuberculosis_H37Rv EVHVTTVLVTHDQAEALDVADRIAVLHKGRIEQVGSPTDVYDAPANAFVM
MMAR_3715|M.marinum_M EVHVTTVLVTHDQAEALDVADRIAVLNSGRIEQVGSPTEVYDAPANAFVM
MUL_3658|M.ulcerans_Agy99 EVHVTTVLVTHDQAEALDVADRIAVLNSGRIEQVGSPTEVYDAPTNAFVM
TH_2424|M.thermoresistible__bu EVHVTTVLVTHDQSEALDVADRIAVLNNGRIEQVGSPAEVYDSPANEFVM
MSMEG_2502|M.smegmatis_MC2_155 ELSCGVLFITHSIQEAVLLSDRVLVMSA----------------------
Mvan_3141|M.vanbaalenii_PYR-1 QHSFAGLFVTHSVEEAVFLSNRVVVMSA----------------------
Mflv_0722|M.gilvum_PYR-GCK ESGRTTVFVTHSADEAAFLGSRIVVLTR----------------------
MAB_2178|M.abscessus_ATCC_1997 ESGRTTVFVTHSADEAAFLGSRIVVLTR----------------------
MAV_3398|M.avium_104 THPTTIVFVTHDVDEALALGDRIVVLG-----------------------
MLBr_01089|M.leprae_Br4923 RLGATTVYVTHDQTEAMTLGDRVVVMRSGVVQQIGTPDELYERPVNLFVA
: :**. ** :..*: *:
Mb2419c|M.bovis_AF2122/97 SFL------------------------------------GAVSTLNGSLV
Rv2397c|M.tuberculosis_H37Rv SFL------------------------------------GAVSTLNGSLV
MMAR_3715|M.marinum_M SFL------------------------------------GAVSALNGALV
MUL_3658|M.ulcerans_Agy99 SFL------------------------------------GAVSALNGALV
TH_2424|M.thermoresistible__bu SFL------------------------------------GAVSSLNGTLV
MSMEG_2502|M.smegmatis_MC2_155 --------------------------------------------------
Mvan_3141|M.vanbaalenii_PYR-1 --------------------------------------------------
Mflv_0722|M.gilvum_PYR-GCK --------------------------------------------------
MAB_2178|M.abscessus_ATCC_1997 --------------------------------------------------
MAV_3398|M.avium_104 --------------------------------------------------
MLBr_01089|M.leprae_Br4923 GFIGSPVMNFFPAKLTPNGLTLPLGELNLSRDVQAMIGQHPVPDRVIVGV
Mb2419c|M.bovis_AF2122/97 RPHDIRVGRTPNMAVAAADGTAGSTGVLRAVVDRVVVLGFEVRVELTSAA
Rv2397c|M.tuberculosis_H37Rv RPHDIRVGRTPNMAVAAADGTAGSTGVLRAVVDRVVVLGFEVRVELTSAA
MMAR_3715|M.marinum_M RPHDIRVGRTPEMAVAAADGTGESTGVTRAVVDRIVVLGFEVRVELTSAA
MUL_3658|M.ulcerans_Agy99 RPHDIRVGRTPEMAVAAADGTGESTGVTRAVVDRIVVLGFEVRVELTSAA
TH_2424|M.thermoresistible__bu RPHDIWVGRHPELPTS--DSTLQATGVVRARIDRVVMLGFEVRLELTSAT
MSMEG_2502|M.smegmatis_MC2_155 RPGTILDEIHVDLPRP-------------------------RDEHTLASP
Mvan_3141|M.vanbaalenii_PYR-1 RPGRIVDEFTVPFEFP-------------------------RALELRYQP
Mflv_0722|M.gilvum_PYR-GCK RPGQIALDIPVDLPRTG-----------------------VDPEELRRSP
MAB_2178|M.abscessus_ATCC_1997 RPGQVALDIPVDLPRTG-----------------------IDPDDLRRSP
MAV_3398|M.avium_104 RAG-EPPRASVEVPEP------------------------------RSDR
MLBr_01089|M.leprae_Br4923 RPEHLTDAKLIDAHQHGTVLTFKVKVDLVESLGADKYIYFTTTGCDVYSA
*.
Mb2419c|M.bovis_AF2122/97 TGGAFTAQITRGDAEALALREGDTVYVRATRVPPIAGGVSGVDDAGVERV
Rv2397c|M.tuberculosis_H37Rv TGGAFTAQITRGDAEALALREGDTVYVRATRVPPIAGGVSGVDDAGVERV
MMAR_3715|M.marinum_M TGGAFTAQITRGDAEALALQEGDTVYVRATRVPPIAGAAPAVPDDGAGST
MUL_3658|M.ulcerans_Agy99 TGGAFTAQITRGDAEALALQEGDTVYVRATRVPPIAGAAPAVPDDGAGST
TH_2424|M.thermoresistible__bu NNAPFTAQITRGDAEALGLRSGDTVYVRATRVPALP--TGDVDERVAAR-
MSMEG_2502|M.smegmatis_MC2_155 RMAALTERIWAQLKDEAGKAMEATLR------------------------
Mvan_3141|M.vanbaalenii_PYR-1 EFAELAGRVAKSLEEAS---------------------------------
Mflv_0722|M.gilvum_PYR-GCK EYGELRAEVGAAVRRAAA--------------------------------
MAB_2178|M.abscessus_ATCC_1997 EYAQLRTEVGRAVKAAAA--------------------------------
MAV_3398|M.avium_104 PHAELRAQIIDALNHAEAA-------------------------------
MLBr_01089|M.leprae_Br4923 QLDELASELEVRENQFVARVSAESKMAIGESIELAFGTAKIAVFDADSGV
: .:
Mb2419c|M.bovis_AF2122/97 KVTST------
Rv2397c|M.tuberculosis_H37Rv KVTST------
MMAR_3715|M.marinum_M PSAAQIGVGGQ
MUL_3658|M.ulcerans_Agy99 PRAAQIGVGGQ
TH_2424|M.thermoresistible__bu -----------
MSMEG_2502|M.smegmatis_MC2_155 -----------
Mvan_3141|M.vanbaalenii_PYR-1 -----------
Mflv_0722|M.gilvum_PYR-GCK -----------
MAB_2178|M.abscessus_ATCC_1997 -----------
MAV_3398|M.avium_104 -----------
MLBr_01089|M.leprae_Br4923 NLTVSAPTDA-