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MDRDGIRIEDVSVVFDVPAGKVTAVAGIDQHVPHASFVSIVGPSGCGKSTLLAVIAGLQKASTGQVRVAG KPVTGPDPSIGVVFQEDSTLPWRTVEENVAFAMEMIGVEKAERRQRARKAIELVGLDGFEKSYPSMLSGG MRQRVALARTLAVEPEVVLMDEPFAALDQQTRLFLGAEIRQIWARTHQTIVFVTHDISEAILLSQQVWVM SYRPGSIIDVVDIDLPAERDASMVSTPEFNELQNRIWTSLQAESMRGFKQQETATT
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. smegmatis MC2 155 | MSMEG_2459 | - | - | 100% (266) | transporter ATPase |
| M. smegmatis MC2 155 | MSMEG_2502 | - | 3e-67 | 52.34% (235) | transporter ATPase |
| M. smegmatis MC2 155 | MSMEG_2633 | - | 4e-60 | 48.77% (244) | ABC transporter ATP-binding protein |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb2419c | cysA1 | 4e-40 | 43.33% (210) | sulfate-transport ATP-binding protein ABC transporter CysA1 |
| M. gilvum PYR-GCK | Mflv_0722 | - | 4e-43 | 40.32% (248) | ABC transporter related |
| M. tuberculosis H37Rv | Rv2397c | cysA1 | 4e-40 | 43.33% (210) | sulfate-transport ATP-binding protein ABC transporter CysA1 |
| M. leprae Br4923 | MLBr_01089 | - | 2e-33 | 37.85% (214) | putative ABC-transport protein, ATP-binding component |
| M. abscessus ATCC 19977 | MAB_2178 | - | 7e-44 | 39.92% (253) | ABC transporter ATP-binding protein |
| M. marinum M | MMAR_3715 | cysA1 | 2e-39 | 44.10% (195) | sulfate-transport ATP-binding protein ABC transporter CysA1 |
| M. avium 104 | MAV_0140 | - | 1e-40 | 41.75% (206) | ABC nitrate/sulfonate/bicarbonate transporter, ATPase subunit |
| M. thermoresistible (build 8) | TH_2424 | - | 4e-40 | 44.10% (195) | PUTATIVE sulfate ABC transporter, ATPase subunit |
| M. ulcerans Agy99 | MUL_3658 | cysA1 | 2e-39 | 44.10% (195) | sulfate-transport ATP-binding protein ABC transporter CysA1 |
| M. vanbaalenii PYR-1 | Mvan_3141 | - | 2e-44 | 41.70% (235) | ABC transporter-related protein |
CLUSTAL 2.0.9 multiple sequence alignment
MSMEG_2459|M.smegmatis_MC2_155 -------------MDRDGIRIEDVSVVFDVPAGKVTAVAGIDQHVPHASF
Mvan_3141|M.vanbaalenii_PYR-1 -------------MSR--------------TFGAVDALAPCDLAVKRGEF
Mflv_0722|M.gilvum_PYR-GCK MSSQSDTEPVAPQRRSGAIQIRSVSHRYGQGRDEVTALGPVDLTVEPGSF
MAB_2178|M.abscessus_ATCC_1997 MPLVDEAETAVQERDTGSIRISGVTHSYGSGAGKTTALGPVDLTVEPGTF
Mb2419c|M.bovis_AF2122/97 ------------MT------YAIVVADATKRYGDFVALDHVDFVVPTGSL
Rv2397c|M.tuberculosis_H37Rv ------------MT------YAIVVADATKRYGDFVALDHVDFVVPTGSL
MMAR_3715|M.marinum_M ------MKKETSLTGPGTGGHAIVVRDAFKQYGDFVALDHVDFVVPAGSL
MUL_3658|M.ulcerans_Agy99 ------------MTGPGTGGHAIVVRDAFKQYGDFVALDHVDFVVPAGSL
TH_2424|M.thermoresistible__bu ------------MT------DAITVRGANKRYGDFAALDNVDFAVPAGSL
MAV_0140|M.avium_104 ------------------------------------MLRDVDVEIEPGAV
MLBr_01089|M.leprae_Br4923 ------------------MAEIVLEHVNKNYPNGATAVHDLSITVADGEF
: . : . .
MSMEG_2459|M.smegmatis_MC2_155 VSIVGPSGCGKSTLLAVIAGLQKASTGQVRVAGK---PVTGPDPSIGVVF
Mvan_3141|M.vanbaalenii_PYR-1 ISIIGPSGCGKSTLLRLASKLDEPTAGAVEFA----------TDSVGYVF
Mflv_0722|M.gilvum_PYR-GCK LVLVGASGCGKSTLLRLLAGFESPTDGSVDVEG----VPPTPGVTAGVVF
MAB_2178|M.abscessus_ATCC_1997 LVLVGASGCGKSTLLRLLAGFESPSEGAVRVAG----GVPTPGITSGVVF
Mb2419c|M.bovis_AF2122/97 TALLGPSGSGKSTLLRTIAGLDQPDTGTITINGRDVTRVPPQRRGIGFVF
Rv2397c|M.tuberculosis_H37Rv TALLGPSGSGKSTLLRTIAGLDQPDTGTITINGRDVTRVPPQRRGIGFVF
MMAR_3715|M.marinum_M TALLGPSGSGKSTLLRTIAGLDQPDSGNITINGRDVTRVPPQRRGIGFVF
MUL_3658|M.ulcerans_Agy99 TALLGPSGSGKSTLLRTIAGLDQPDSGNITINGRDVTRVPPQRRGIGFVF
TH_2424|M.thermoresistible__bu TALLGPSGSGKSTLLRAIAGLDRPDTGTITINGRDVTDVPPQRRGIGFVF
MAV_0140|M.avium_104 VALLGASGSGKSTLLRLVAGLDRPSGGRIEIDGKAVRGIDPR---CAVVF
MLBr_01089|M.leprae_Br4923 LILIGPSGCGKTTTLNMIAGLEDISSGELRIDGDRVNEKAPKDRDIAMVF
::*.**.**:* * : :: * : . . **
MSMEG_2459|M.smegmatis_MC2_155 QEDSTLPWRTVEENVAFAMEMIGVEKAERRQRARKAIELVGLDGFEKSYP
Mvan_3141|M.vanbaalenii_PYR-1 QDATLMPWRTVRRNVGLLAELQGRGRAEIRSEVESALATVGLTDFAEHLP
Mflv_0722|M.gilvum_PYR-GCK QQPRLFPWRTVGGNVELALKYAKVPRDKRSERRDELLERVGLGGTAGRRI
MAB_2178|M.abscessus_ATCC_1997 QQPRLFPWRTVGGNIELALKYAKVPRERWAQRRDQLLARVGLEGTAGRRI
Mb2419c|M.bovis_AF2122/97 QHYAAFKHLTVRDNVAFGLKIRKRPKAEIKAKVDNLLQVVGLSGFQSRYP
Rv2397c|M.tuberculosis_H37Rv QHYAAFKHLTVRDNVAFGLKIRKRPKAEIKAKVDNLLQVVGLSGFQSRYP
MMAR_3715|M.marinum_M QHYAAFKHLTVRDNVAYGLKIRKRPKAEIRDKVDNLLEVVGLSGFHGRYP
MUL_3658|M.ulcerans_Agy99 QHYAAFKHLTVRDNVAYGLKIRKRPKAEIRDKVDNLLEVVGLSGFHGRYP
TH_2424|M.thermoresistible__bu QHYAAFKHLTVRDNVAFGLKIRRRPKREIAEKVDNLLEVVGLAGFQNRYP
MAV_0140|M.avium_104 QEPRLLPWRSLAANVAFGLP-RGTERPERTAAVQRWLDVVGLREFAGHYP
MLBr_01089|M.leprae_Br4923 QSYALYPHMTVRQNIAFPLMLAKVKKAEIAQKVSETAQILDLTDLLDRKP
* :: *: : . :.*
MSMEG_2459|M.smegmatis_MC2_155 SMLSGGMRQRVALARTLAVEPEVVLMDEPFAALDQQTRLFLGAEIRQIWA
Mvan_3141|M.vanbaalenii_PYR-1 RQLSGGMKMRASLARSLVLKPEVFLFDEPFGALDEITRGRLNLVLQDLFL
Mflv_0722|M.gilvum_PYR-GCK WEISGGQQQRVAIARALAAETPLFLLDEPFAALDALTRERLQEDVRQVSA
MAB_2178|M.abscessus_ATCC_1997 WEISGGQQQRVAIARALAAETPLFLLDEPFAALDALTRERLQEDVRQVSA
Mb2419c|M.bovis_AF2122/97 NQLSGGQRQRMALARALAVDPEVLLLDEPFGALDAKVREELRAWLRRLHD
Rv2397c|M.tuberculosis_H37Rv NQLSGGQRQRMALARALAVDPEVLLLDEPFGALDAKVREELRAWLRRLHD
MMAR_3715|M.marinum_M NQLSGGQRQRMALARALAVDPEVLLLDEPFGALDAKVREDLRAWLRRLHD
MUL_3658|M.ulcerans_Agy99 DQLSGGQRQRMALARALAVDPEVLLLDEPFGALDAKVREDLRAWLRRLHD
TH_2424|M.thermoresistible__bu NQLSGGQRQRMALARALAVDPEVLLLDEPFGALDAKVREDLRTWLRRLHE
MAV_0140|M.avium_104 RQVSGGMAQRAGLARALARQPSVLLLDEPLAALDALTRLRMQDLLDAVQQ
MLBr_01089|M.leprae_Br4923 SQLSGGQRQRVAMGRAIVRHPKAFLMDEPLSNLDAKLRVRTRGEIARLQR
:*** * .:.*::. .. .*:***:. ** * : :
MSMEG_2459|M.smegmatis_MC2_155 RTHQTIVFVTHDISEAILLSQQVWVMSYRPGSIIDVVD------------
Mvan_3141|M.vanbaalenii_PYR-1 QHSFAGLFVTHSVEEAVFLSNRVVVMSARPGRIVDEFT------------
Mflv_0722|M.gilvum_PYR-GCK ESGRTTVFVTHSADEAAFLGSRIVVLTRRPGQIALDIP------------
MAB_2178|M.abscessus_ATCC_1997 ESGRTTVFVTHSADEAAFLGSRIVVLTRRPGQVALDIP------------
Mb2419c|M.bovis_AF2122/97 EVHVTTVLVTHDQAEALDVADRIAVLHKGRIEQVGSPTDVYDAPANAFVM
Rv2397c|M.tuberculosis_H37Rv EVHVTTVLVTHDQAEALDVADRIAVLHKGRIEQVGSPTDVYDAPANAFVM
MMAR_3715|M.marinum_M EVHVTTVLVTHDQAEALDVADRIAVLNSGRIEQVGSPTEVYDAPANAFVM
MUL_3658|M.ulcerans_Agy99 EVHVTTVLVTHDQAEALDVADRIAVLNSGRIEQVGSPTEVYDAPTNAFVM
TH_2424|M.thermoresistible__bu EVHVTTVLVTHDQSEALDVADRIAVLNNGRIEQVGSPAEVYDSPANEFVM
MAV_0140|M.avium_104 RAGTTTILVTHDVEEAVLLADRVLILRG---EEGGAAT------------
MLBr_01089|M.leprae_Br4923 RLGATTVYVTHDQTEAMTLGDRVVVMRSGVVQQIGTPDELYERPVNLFVA
. : : ***. ** :..:: ::
MSMEG_2459|M.smegmatis_MC2_155 --------------------------IDLPAE--RDASMVSTPEFNELQN
Mvan_3141|M.vanbaalenii_PYR-1 --------------------------VPFEFP--RALELRYQPEFAELAG
Mflv_0722|M.gilvum_PYR-GCK --------------------------VDLPRTGVDPEELRRSPEYGELRA
MAB_2178|M.abscessus_ATCC_1997 --------------------------VDLPRTGIDPDDLRRSPEYAQLRT
Mb2419c|M.bovis_AF2122/97 SFL------------------GAVSTLNGSLVRPHDIRVGRTPNMAVAAA
Rv2397c|M.tuberculosis_H37Rv SFL------------------GAVSTLNGSLVRPHDIRVGRTPNMAVAAA
MMAR_3715|M.marinum_M SFL------------------GAVSALNGALVRPHDIRVGRTPEMAVAAA
MUL_3658|M.ulcerans_Agy99 SFL------------------GAVSALNGALVRPHDIRVGRTPEMAVAAA
TH_2424|M.thermoresistible__bu SFL------------------GAVSSLNGTLVRPHDIWVGRHPELPTS--
MAV_0140|M.avium_104 ----------------------VAATHDVAIPKPRDR---GDPRIAALR-
MLBr_01089|M.leprae_Br4923 GFIGSPVMNFFPAKLTPNGLTLPLGELNLSRDVQAMIGQHPVPDRVIVGV
*
MSMEG_2459|M.smegmatis_MC2_155 RIWTSLQAESMR--------GFKQQETATT--------------------
Mvan_3141|M.vanbaalenii_PYR-1 RVAKSLEEAS----------------------------------------
Mflv_0722|M.gilvum_PYR-GCK EVGAAVRRAAA---------------------------------------
MAB_2178|M.abscessus_ATCC_1997 EVGRAVKAAAA---------------------------------------
Mb2419c|M.bovis_AF2122/97 DGTAGSTGVLRAVVDRVVVLGFEVRVELTSAATGGAFTAQITRGDAEALA
Rv2397c|M.tuberculosis_H37Rv DGTAGSTGVLRAVVDRVVVLGFEVRVELTSAATGGAFTAQITRGDAEALA
MMAR_3715|M.marinum_M DGTGESTGVTRAVVDRIVVLGFEVRVELTSAATGGAFTAQITRGDAEALA
MUL_3658|M.ulcerans_Agy99 DGTGESTGVTRAVVDRIVVLGFEVRVELTSAATGGAFTAQITRGDAEALA
TH_2424|M.thermoresistible__bu DSTLQATGVVRARIDRVVMLGFEVRLELTSATNNAPFTAQITRGDAEALG
MAV_0140|M.avium_104 EQLLEEVGVPRR--------GYAIEQEAKTS-------------------
MLBr_01089|M.leprae_Br4923 RPEHLTDAKLIDAHQHGTVLTFKVKVDLVESLGADKYIYFTTTGCDVYSA
MSMEG_2459|M.smegmatis_MC2_155 --------------------------------------------------
Mvan_3141|M.vanbaalenii_PYR-1 --------------------------------------------------
Mflv_0722|M.gilvum_PYR-GCK --------------------------------------------------
MAB_2178|M.abscessus_ATCC_1997 --------------------------------------------------
Mb2419c|M.bovis_AF2122/97 LREGDTVYVRATRVPPIAGGVSGVDDAGVERVKVTST-------------
Rv2397c|M.tuberculosis_H37Rv LREGDTVYVRATRVPPIAGGVSGVDDAGVERVKVTST-------------
MMAR_3715|M.marinum_M LQEGDTVYVRATRVPPIAGAAPAVPDDGAGSTPSAAQIGVGGQ-------
MUL_3658|M.ulcerans_Agy99 LQEGDTVYVRATRVPPIAGAAPAVPDDGAGSTPRAAQIGVGGQ-------
TH_2424|M.thermoresistible__bu LRSGDTVYVRATRVPALP--TGDVDERVAAR-------------------
MAV_0140|M.avium_104 --------------------------------------------------
MLBr_01089|M.leprae_Br4923 QLDELASELEVRENQFVARVSAESKMAIGESIELAFGTAKIAVFDADSGV
MSMEG_2459|M.smegmatis_MC2_155 ----------
Mvan_3141|M.vanbaalenii_PYR-1 ----------
Mflv_0722|M.gilvum_PYR-GCK ----------
MAB_2178|M.abscessus_ATCC_1997 ----------
Mb2419c|M.bovis_AF2122/97 ----------
Rv2397c|M.tuberculosis_H37Rv ----------
MMAR_3715|M.marinum_M ----------
MUL_3658|M.ulcerans_Agy99 ----------
TH_2424|M.thermoresistible__bu ----------
MAV_0140|M.avium_104 ----------
MLBr_01089|M.leprae_Br4923 NLTVSAPTDA