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VDMGNVSYAATPSERESVCGHTALYRRRSAPGARTSFSCQDDLRVVPDDGVGLLRDTRILVVDDSTLYRD YLAAALAAHGAVAPGVAWDGPSLLASFDATMPRVILLNMATRDSATLLKQALALGPHTRVVVIGIAEDDE SAIVACAEAGVAGYHSRSESLDELLELIHKVAVGETLCSPKVSAILLRRLSTLAAQREPAPTELVLTRRE IEILRMLEAGRTNREIAEQLCIAVHTVKSHVHNLLAKLGVSTRAQAAALSRTMRYTADPQED
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. smegmatis MC2 155 | MSMEG_0473 | - | - | 100% (272) | transcriptional regulator, LuxR family protein |
| M. smegmatis MC2 155 | MSMEG_5987 | - | 2e-89 | 72.77% (224) | two-component regulator |
| M. smegmatis MC2 155 | MSMEG_3240 | - | 4e-21 | 34.45% (209) | DNA-binding response regulator, LuxR family protein |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb0867c | narL | 2e-18 | 31.43% (210) | nitrate/nitrite response transcriptional regulatory protein |
| M. gilvum PYR-GCK | Mflv_3579 | - | 1e-19 | 31.90% (210) | two component LuxR family transcriptional regulator |
| M. tuberculosis H37Rv | Rv0844c | narL | 1e-18 | 31.43% (210) | nitrate/nitrite response transcriptional regulatory protein |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | MAB_3714c | - | 2e-19 | 31.66% (199) | two-component LuxR family response regulator |
| M. marinum M | MMAR_3959 | - | 2e-19 | 30.00% (200) | two-component transcriptional regulatory protein |
| M. avium 104 | MAV_4114 | - | 2e-22 | 30.54% (203) | response regulator receiver domain-containing protein |
| M. thermoresistible (build 8) | TH_3563 | - | 3e-21 | 32.20% (205) | PUTATIVE DNA-binding response regulator, LuxR family protein |
| M. ulcerans Agy99 | MUL_0351 | narL | 4e-19 | 32.35% (204) | nitrate/nitrite response regulator protein NarL |
| M. vanbaalenii PYR-1 | Mvan_2836 | - | 2e-20 | 32.20% (205) | two component LuxR family transcriptional regulator |
CLUSTAL 2.0.9 multiple sequence alignment
MMAR_3959|M.marinum_M -------------------------------------------------M
MAV_4114|M.avium_104 -------------------------------------------------M
Mflv_3579|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_2836|M.vanbaalenii_PYR-1 --------------------------------------------------
TH_3563|M.thermoresistible__bu --------------------------------------------------
MAB_3714c|M.abscessus_ATCC_199 --------------------------------------------------
Mb0867c|M.bovis_AF2122/97 ------------------------------------------------MS
Rv0844c|M.tuberculosis_H37Rv ------------------------------------------------MS
MUL_0351|M.ulcerans_Agy99 ------------------------------------------------MD
MSMEG_0473|M.smegmatis_MC2_155 MDMGNVSYAATPSERESVCGHTALYRRRSAPGARTSFSCQDDLRVVPDDG
MMAR_3959|M.marinum_M SEHESP-TVMVVDDHPIWRDAVARDLS-DDGFAVVATADGVATAQRRAAI
MAV_4114|M.avium_104 TDDATPTTVMVVDDHPIWRDAVARDLA-ESGFAVVATADGVATAQRRAGV
Mflv_3579|M.gilvum_PYR-GCK MG-IDRTSVMVVDDHPIWRDAVARDLA-DDGFDVVATADGVASAKRRAAV
Mvan_2836|M.vanbaalenii_PYR-1 --------MMVVDDHPIWRDAVARDLA-DDGFDVVATADGVASAKRRAAV
TH_3563|M.thermoresistible__bu MGEPQQPTVMVVDDHPIWREAVARDLA-EAGLSVVATADGVAAARRRAAA
MAB_3714c|M.abscessus_ATCC_199 ----MMLRVFLVDDHGVFRSGVRAELAGESDIEIVGEAGSVVEAVAGIRS
Mb0867c|M.bovis_AF2122/97 NPQPEKVRVVVGDDHPLFREGVVRALSLSGSVNVVGEADDGAAALELIKA
Rv0844c|M.tuberculosis_H37Rv NPQPEKVRVVVGDDHPLFREGVVRALSLSGSVNVVGEADDGAAALELIKA
MUL_0351|M.ulcerans_Agy99 VTKTEKVRVVVGDDHPLFREGVVRALSLSGSVNVVGEADDGAAALELIET
MSMEG_0473|M.smegmatis_MC2_155 VGLLRDTRILVVDDSTLYRDYLAAALA-AHGAVAPGVAWDGPSLLASFDA
:.: ** ::*. : *: . . * .
MMAR_3959|M.marinum_M VKPDVVVMDMRLADGDGVQATTEVL-KVSPATRVLVLSAS-DEREDVLEA
MAV_4114|M.avium_104 VRPDVVVMDMQLPDGDGAQATAAVL-AVSPSSRVLVLSAS-DERDDVLQA
Mflv_3579|M.gilvum_PYR-GCK VRPDVVVMDMRLGDGDGAQATTEVL-AVSPSSRILVLSAS-DERDDVLEA
Mvan_2836|M.vanbaalenii_PYR-1 VQPAVVLMDMRLADGDGAQATAEVL-AVSPSSRVLVLSAS-DERDDVLEA
TH_3563|M.thermoresistible__bu VRPDVVLMDMRLPDGDGARATAEVR-AVSPDSRVLVLSAS-EERDDVLEA
MAB_3714c|M.abscessus_ATCC_199 SAPDVVLLDVHMPSGGGVAVINGTIGPVCP--VFLALSVS-DAAEDVIAV
Mb0867c|M.bovis_AF2122/97 HLPDVALLDYRMPGMDGAQVPAAVR-SYELPTRVLLISAH-DEPAIVYQA
Rv0844c|M.tuberculosis_H37Rv HLPDVALLDYRMPGMDGAQVAAAVR-SYELPTRVLLISAH-DEPAIVYQA
MUL_0351|M.ulcerans_Agy99 HLPDVALLDYRMPRMDGAQVAAAVR-SNGLPTRVLLISAH-DESAIVYQA
MSMEG_0473|M.smegmatis_MC2_155 TMPRVILLNMATRDSATLLKQALAL---GPHTRVVVIGIAEDDESAIVAC
* * ::: . .: :. : :
MMAR_3959|M.marinum_M VKAGATGYLVKSASKAELADAVRATAAGRAVFTPSLAGLVLGEY--RRIA
MAV_4114|M.avium_104 VKAGAAGYLVKSASKAELAQAVTDTAAGRAVFTPSLAGLVLGEY--RRIA
Mflv_3579|M.gilvum_PYR-GCK VKAGATGYLVKSASKQELGDAVRATAQGRAVFTPGLAGLVLGEF--RRIE
Mvan_2836|M.vanbaalenii_PYR-1 VKAGATGYLVKSASKQELGDAVRATAQGRAVFTPGLAGLVLGEF--RRIE
TH_3563|M.thermoresistible__bu VKAGATGYLVKSASKTELVDAVHATAQGRAVFTPGLAGLVLGEY--RRIS
MAB_3714c|M.abscessus_ATCC_199 IRAGARGYVTKTISGSELADAVRRVAGGDAVFSPRLAGFVLDSFTGRSNA
Mb0867c|M.bovis_AF2122/97 LQQGAAGFLLKDSTRTEIVKAVLDCAKGRDVVAPSLVGGLAGEI------
Rv0844c|M.tuberculosis_H37Rv LQQGAAGFLLKDSTRTEIVKAVLDCAKGRDVVAPSLVGGLAGEI------
MUL_0351|M.ulcerans_Agy99 LQQGAAGFLLKDSTRTEIVKAVLDCAKGRDVVAPSLVGGLAGEI------
MSMEG_0473|M.smegmatis_MC2_155 AEAGVAGYHSRSESLDELLELIHKVAVGETLCSPKVSAILLRRLS--TLA
. *. *: : : *: . : * * : :* : . :
MMAR_3959|M.marinum_M QTADSSQDRPSLTERETEILRYVAKGLSAKQIAEKLSLSHRTVENHVQAT
MAV_4114|M.avium_104 QSKDDGPTRPRLTDRETEVLRYVAKGLSAKQIAEKLSLSHRTVENHVQAT
Mflv_3579|M.gilvum_PYR-GCK QSSPAGADGPTLTERETEILRYVAKGLTAKQIASRLSLSHRTVENHVQAT
Mvan_2836|M.vanbaalenii_PYR-1 RDSPAG---PTLTERETEILRHVAKGLTAKQIASRLSLSHRTVENHVQAT
TH_3563|M.thermoresistible__bu RQPGAGPDAPRLTERETEILRYVAKGLTAKQIAAQLSLSHRTVENHVQAT
MAB_3714c|M.abscessus_ATCC_199 PEPALDPELDSLTPRELEVLRLLARGYTYREIAEDLVISVKTVETHASNV
Mb0867c|M.bovis_AF2122/97 -RQRAAPVAPVLSAREREVLNRIACGQSIPAIAAELYVAPSTVKTHVQRL
Rv0844c|M.tuberculosis_H37Rv -RQRAAPVAPVLSAREREVLNRIACGQSIPAIAAELYVAPSTVKTHVQRL
MUL_0351|M.ulcerans_Agy99 -RQRAAPMAPVLSAREREVLHRIAKGQSIPAIAGELYVAPSTVKTHVQRL
MSMEG_0473|M.smegmatis_MC2_155 AQREPAPTELVLTRREIEILRMLEAGRTNREIAEQLCIAVHTVKSHVHNL
*: ** *:*. : * : ** * :: **:.*.
MMAR_3959|M.marinum_M FRKLQVANRVELTRYAIEHGLDK-----
MAV_4114|M.avium_104 FRKLQVANRVELARYAIEHGLDEEP---
Mflv_3579|M.gilvum_PYR-GCK FRKLQVGNRVELARYAIEHGLDE-----
Mvan_2836|M.vanbaalenii_PYR-1 FRKLQIGNRVELARYAIEHGLDE-----
TH_3563|M.thermoresistible__bu FRKLQVANRVELARYAIEHGLDE-----
MAB_3714c|M.abscessus_ATCC_199 LRKTQQSNRNALTRWAHTRQLD------
Mb0867c|M.bovis_AF2122/97 YEKLGVSDRAAAVAEAMRQRLLD-----
Rv0844c|M.tuberculosis_H37Rv YEKLGVSDRAAAVAEAMRQRLLD-----
MUL_0351|M.ulcerans_Agy99 YEKLGVSDRAAAVAEAMRQGLLD-----
MSMEG_0473|M.smegmatis_MC2_155 LAKLGVSTRAQAAALSRTMRYTADPQED
* . * . :