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SDESSATALLSPALSRAGLGWGFLGVAAFSFTVIFTRVALGGLSPLFIGAGRAVVAAALAAAALTFTRAA LPRGRQWLRLGVVAAGVVAGFPLLTSYALTTVPATHGAVVIALLPAATAVAAVLRCREHPPLAFWAAAGA GALAAVVFAMLHGGGVGQLHWADLLLFGAVIAAAIGYAEGGLLARELGSWQTVSWALVVAAPVMVALTAA AVVDRPPQAGAGEWAAFGYLAAVSMFLGFFAWYRGLAIGPMAQVSQVQLVQPVLTICWAALLLHESLTWT TACGGAAVVASAGFAVRMRRSPRANSHAGT*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. smegmatis MC2 155 | MSMEG_0425 | - | - | 100% (311) | putative membrane protein DcsA |
| M. smegmatis MC2 155 | MSMEG_3314 | - | 9e-07 | 30.84% (214) | transport protein |
| M. smegmatis MC2 155 | MSMEG_1571 | - | 9e-06 | 29.05% (241) | integral membrane protein |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb3478 | - | 7e-05 | 26.32% (285) | integral membrane protein |
| M. gilvum PYR-GCK | Mflv_1402 | - | 3e-05 | 26.02% (246) | putative integral membrane protein |
| M. tuberculosis H37Rv | Rv3448 | - | 7e-05 | 26.32% (285) | integral membrane protein |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | MAB_0811 | - | 3e-53 | 42.21% (289) | membrane protein (resistance to D-cycloserine) |
| M. marinum M | MMAR_4903 | - | 4e-09 | 27.48% (302) | hypothetical protein MMAR_4903 |
| M. avium 104 | MAV_4712 | - | 2e-05 | 29.19% (185) | transporter, major facilitator family protein |
| M. thermoresistible (build 8) | TH_4594 | - | 2e-07 | 26.76% (284) | PUTATIVE putative conserved hypothetical protein |
| M. ulcerans Agy99 | MUL_0503 | - | 6e-09 | 27.48% (302) | hypothetical protein MUL_0503 |
| M. vanbaalenii PYR-1 | - | - | - | - | - |
CLUSTAL 2.0.9 multiple sequence alignment
MMAR_4903|M.marinum_M -------------MPALAMGVTVTLWAFAFVGVRSAGRVFSPGVLALSRL
MUL_0503|M.ulcerans_Agy99 MASSTTSSQRTVNMPALAMGVTVTLWAFAFVGVRSAGRVFSPGVLALSRL
MSMEG_0425|M.smegmatis_MC2_155 ------MSDESSATALLSPALSRAGLGWGFLGVAAFSFTVIFTRVALGGL
MAB_0811|M.abscessus_ATCC_1997 ------MQAG-------TPSLS-KGTGLAALGVLSFSLSFPATAWALEGF
Mb3478|M.bovis_AF2122/97 ------MPTSDPGLRRVTVHAGAQAVDLTLPAAVPVATLIPSIVDILGDR
Rv3448|M.tuberculosis_H37Rv ------MPTSDPGLRRVTVHAGAQAVDLTLPAAVPVATLIPSIVDILGDR
TH_4594|M.thermoresistible__bu -MLARRWDSEHLGLLVLVPLVLLAPVITDGITVVLIGFMLALGAASLPVQ
Mflv_1402|M.gilvum_PYR-GCK ----MTDATAGPSGAVSRASVVRVGVATALSALCGYAVLYLAARDLEPAG
MAV_4712|M.avium_104 -----MTDSSPPAKGTFTVEMLSRAKRGVTAVFVAHGLLFASWAAHIPQV
.
MMAR_4903|M.marinum_M F--------IAVMVMAVIAT-----------------IAATYTAYAGRAT
MUL_0503|M.ulcerans_Agy99 F--------IAVMVMAVIAT-----------------IAATYTAYAGRAT
MSMEG_0425|M.smegmatis_MC2_155 S--------PLFIGAGR--------------------AVVAAALAAAALT
MAB_0811|M.abscessus_ATCC_1997 G--------PWSATGIR--------------------GAVAAALALIALG
Mb3478|M.bovis_AF2122/97 G--------ASPATAARYQLSALGAPALPNATTLAQCGIRDGAVLVLHKS
Rv3448|M.tuberculosis_H37Rv G--------ASPATAARYQLSALGAPALPNATTLAQCGIRDGAVLVLHKS
TH_4594|M.thermoresistible__bu LGRDWIWLHAARTASVTLPILGALLGASFAQDRVPALTAACGIAAVLALA
Mflv_1402|M.gilvum_PYR-GCK FS-------VFGVFWGAFGLVSG-----------AAFGLLQETTREVRHP
MAV_4712|M.avium_104 KAG-------LGLDDAALGT-----------------ALFGAPLGSVLAT
MMAR_4903|M.marinum_M TRRLRPPSAAALTLVIAYGVAWFGAYSIVISWAEQHIDAGTTALLVNLAP
MUL_0503|M.ulcerans_Agy99 TRRLRPPSAAALTLVIAYGVAWFGAYSIVISWAEQHIDAGTTALLVNLAP
MSMEG_0425|M.smegmatis_MC2_155 FTRAALPRGRQWLRLGVVAAGVVAGFPLLTSYALTTVPATHGAVVIALLP
MAB_0811|M.abscessus_ATCC_1997 VARSPLPARSDWGALAVVAIGCAVGFPLLTTLALQTSSTAHSAVVIGALP
Mb3478|M.bovis_AF2122/97 SAQPPTPRCDDVAEAVAAALDTTARPQCQRTTRLSGALAASCITAGGGLM
Rv3448|M.tuberculosis_H37Rv SAQPPTPRCDDVAEAVAAALDTTARPQCQRTTRLSGALAASCITAGGGLM
TH_4594|M.thermoresistible__bu AALLLAPSTRNHTALGLLTAAGTLPVLCVSWAERPAVSALMAAALSAALL
Mflv_1402|M.gilvum_PYR-GCK SAGTAHRHTRPLAVAAAVGVAAAAAIGVSAPLWSAHVFVDARMLSVALLC
MAV_4712|M.avium_104 LAGHWALPRWGSHRLIPVTVAGYAAAGTTVGLARSGPALFAALALWGMFQ
MMAR_4903|M.marinum_M ILVAVFAGFFLGEGYSARLLTGIA-------------------IAFAGVV
MUL_0503|M.ulcerans_Agy99 ILVAVFAGFFLGEGYSARLLTGIA-------------------IAFAGVV
MSMEG_0425|M.smegmatis_MC2_155 AATAVAAVLRCREHPPLAFWAAAG------------------AGALAAVV
MAB_0811|M.abscessus_ATCC_1997 MATAAIAAVRTGARHSGTFWAAAS------------------VGAATVIV
Mb3478|M.bovis_AF2122/97 LVRNALGTNVTRYSDATAGVVAAAGLAALLFAVIACRTYRDPIAGLTLSV
Rv3448|M.tuberculosis_H37Rv LVRNALGTNVTRYSDATAGVVAAAGLAALLFAVIACRTYRDPIAGLTLSV
TH_4594|M.thermoresistible__bu AMAAGAGLIRVELVRTGPLRRILSVWAAVAALIAVTVAFDAPVAAPVLLA
Mflv_1402|M.gilvum_PYR-GCK AGLAGFCVHTTLLGALAGMGRWSDYGALMVTDAALRVVVAAAGFAAGWGL
MAV_4712|M.avium_104 GALDVAMNTQAGTVERRAGAPMMARFHGMWSLGTLAGALIGAACVGAGIG
MMAR_4903|M.marinum_M LISAGGGGSQTDWLGVGLGLLAAVL---YAAGVLLQKVALRTVDALSATL
MUL_0503|M.ulcerans_Agy99 LISAGGGGSQTDWLGVGLGLLAAVL---YAAGVLLQKVALRTVDALSATL
MSMEG_0425|M.smegmatis_MC2_155 FAMLHGGGVGQLHWADLLLFGAVIA---AAIGYAEGGLLARELGSWQTVS
MAB_0811|M.abscessus_ATCC_1997 FTLAQN--HGRPTLADLYLFAALLV---CAAGYAEGGRLSARMPGWQVIA
Mb3478|M.bovis_AF2122/97 IATIFGAVAGLLAVPGVPGVHSVLV---AAMAAAATSVLAMRITGCGGIT
Rv3448|M.tuberculosis_H37Rv IATIFGAVAGLLAVPGVPGVHSVLV---AAMAAAATSVLAMRITGCGGIT
TH_4594|M.thermoresistible__bu MATVVAVAGRHDRTARWIALGFAVVGGLYYLGVAPPYRVLRPIAVAAPTA
Mflv_1402|M.gilvum_PYR-GCK GGYLWATVAGAFSWLLMLLVSPATR---AAARVQTTGGTATFLRGAGHSM
MAV_4712|M.avium_104 LTAQLTVLGAVVLLVVVMLTRRLLPDAADSVAAPPEPAAGRRVTPAVAIL
:
MMAR_4903|M.marinum_M WGTLVG--FIVTLPFLPAAARELSLASAADLWWLVFLGAGPSAIAFTTWA
MUL_0503|M.ulcerans_Agy99 WGTLVG--FIVTLPFLPAAARELSLASAADLWWLVFLGAGPSAIAFTTWA
MSMEG_0425|M.smegmatis_MC2_155 WALVVAAPVMVALTAAA-VVDRPPQAGAGEWAAFGYLAAVSMFLGFFAWY
MAB_0811|M.abscessus_ATCC_1997 WGVVLAAPVNLLVTVLA-LPHEPVHLNAHALIGMAYLAAISQFGGFVVWY
Mb3478|M.bovis_AF2122/97 LTAVACCAVVVAAATLVGAITAAPVPAIGSLDTLASFGLLEVSARMAVLL
Rv3448|M.tuberculosis_H37Rv LTAVACCAVVVAAATLVGAITAAPVPAIGSLATLASFGLLEVSARMAVLL
TH_4594|M.thermoresistible__bu VAVLIASVLLICCVVAIVWTWRAHVPAAGPLPWLGAATVLLYAVTTFTVT
Mflv_1402|M.gilvum_PYR-GCK AAAGASAVLVMGFPVLLAATSGDLGATGGVVILAVTLTRAPLMVPLTAMQ
MAV_4712|M.avium_104 AAVSFASFLCEGAATDWSATYLRDVVGAGPSVAAASYAAYTLTMVVTRFA
.
MMAR_4903|M.marinum_M YALARTN------------------AGVTAATTLMVPALVIALSGLLLAE
MUL_0503|M.ulcerans_Agy99 YALARTN------------------AGVTAATTLMVPALVIALSGLLLAE
MSMEG_0425|M.smegmatis_MC2_155 RGLAIGP------------------MAQVSQVQLVQPVLTICWAALLLHE
MAB_0811|M.abscessus_ATCC_1997 RGMGFIG------------------VARASQLQLAQPLLTLIWAVLLLDE
Mb3478|M.bovis_AF2122/97 AGLSPRLPPALNPDDADALPTTDRLTTRANRADAWLTSLLAAFAASATIG
Rv3448|M.tuberculosis_H37Rv AGLSPRLPPALNPDDADALPTTDRLTTRANRADAWLTSLLAAFAASATIG
TH_4594|M.thermoresistible__bu AGVLAGG-----------------VGGGFFAGHMAATICWIGLAAALLWY
Mflv_1402|M.gilvum_PYR-GCK GNLIAYFIDQR----AHRLKALLAPSALVAALGAGGVVLAAVFGPWLLRE
MAV_4712|M.avium_104 AGRLHAR------------------LPSRRLLPALAVLAVAGMSVTLATA
.
MMAR_4903|M.marinum_M VPNPLGLAGG-----GACLIGVALARGLLRLPARSRRRTGTGDQLQGVES
MUL_0503|M.ulcerans_Agy99 VPNPLGLAGG-----GACLIGVVLARGLLRLPARSRRRTGTGDQLQGVES
MSMEG_0425|M.smegmatis_MC2_155 SLTWTTACG----------GAAVVASAGFAVRMRRSPRANSHAGT-----
MAB_0811|M.abscessus_ATCC_1997 RFSPAVPLT----------AAVVFTCIVITQRART---------------
Mb3478|M.bovis_AF2122/97 AIGTAVATHGIHRSSMGGIALAAVTGALLLLRARSADTRRSLVFAICGIT
Rv3448|M.tuberculosis_H37Rv AIGTAVATHGIHRSSMGGIALAAVTGALLLLRARSADTRRSLVFAICGIT
TH_4594|M.thermoresistible__bu AARRPRADRAMPLGGGLALVAAAVAKLFLFDLGTLDGIFRVVVFIVVGLV
Mflv_1402|M.gilvum_PYR-GCK AFGAQYRAEG-ALLAWLTVAAVAIALLTLTGAATVAAALHRAYAAGWVIA
MAV_4712|M.avium_104 DAAAGVLGFAALGVGVALLVPTAFSAAYGARGAGSAIAIVAATGWLGYLL
...:
MMAR_4903|M.marinum_M LPVGLSDYAASSTAPSGRQL------------------------------
MUL_0503|M.ulcerans_Agy99 LPVGLSDYAASSTAPSGRQL------------------------------
MSMEG_0425|M.smegmatis_MC2_155 --------------------------------------------------
MAB_0811|M.abscessus_ATCC_1997 --------------------------------------------------
Mb3478|M.bovis_AF2122/97 TVATAFTVAADRALEHGPWIAALTAMLAAVAMFLGFVAPALSLSPVTYRT
Rv3448|M.tuberculosis_H37Rv TVATAFTVAADRALEHGPWIAALTAMLAAVAMFLGFVAPALSLSPVTYRT
TH_4594|M.thermoresistible__bu LLGTGGGYARWLTHAAGESHPAGESRGTGKHQADNEPV------------
Mflv_1402|M.gilvum_PYR-GCK TAAAALLLMLPLDLEVRAVVALLCGPLLGIAVHLSALARDRDGVAPTYAA
MAV_4712|M.avium_104 GPPLIGHLSEWVGLSGALVTIPVMMTIVAVAIRYTPAFDTADEFHRAPAG
MMAR_4903|M.marinum_M ----------------------------------
MUL_0503|M.ulcerans_Agy99 ----------------------------------
MSMEG_0425|M.smegmatis_MC2_155 ----------------------------------
MAB_0811|M.abscessus_ATCC_1997 ----------------------------------
Mb3478|M.bovis_AF2122/97 IELLECLALIAMVPLTAWLCGAYSAVRHLDLTWT
Rv3448|M.tuberculosis_H37Rv IELLECLALIAMVPLTAWLCGAYSAVRHLDLTWT
TH_4594|M.thermoresistible__bu ----------------------------------
Mflv_1402|M.gilvum_PYR-GCK IDD-------------------------------
MAV_4712|M.avium_104 ----------------------------------