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VQAGTPSLSKGTGLAALGVLSFSLSFPATAWALEGFGPWSATGIRGAVAAALALIALGVARSPLPARSDW GALAVVAIGCAVGFPLLTTLALQTSSTAHSAVVIGALPMATAAIAAVRTGARHSGTFWAAASVGAATVIV FTLAQNHGRPTLADLYLFAALLVCAAGYAEGGRLSARMPGWQVIAWGVVLAAPVNLLVTVLALPHEPVHL NAHALIGMAYLAAISQFGGFVVWYRGMGFIGVARASQLQLAQPLLTLIWAVLLLDERFSPAVPLTAAVVF TCIVITQRART
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. abscessus ATCC 19977 | MAB_0811 | - | - | 100% (291) | membrane protein (resistance to D-cycloserine) |
| M. abscessus ATCC 19977 | MAB_0766 | - | 7e-10 | 25.00% (276) | integral membrane protein |
| M. abscessus ATCC 19977 | MAB_0677c | - | 2e-06 | 24.39% (287) | hypothetical protein MAB_0677c |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | - | - | - | - | - |
| M. gilvum PYR-GCK | Mflv_0017 | - | 3e-07 | 26.52% (264) | major facilitator transporter |
| M. tuberculosis H37Rv | - | - | - | - | - |
| M. leprae Br4923 | - | - | - | - | - |
| M. marinum M | MMAR_0549 | - | 1e-05 | 26.94% (193) | transmembrane protein |
| M. avium 104 | MAV_4863 | - | 0.0001 | 27.27% (198) | hypothetical protein MAV_4863 |
| M. smegmatis MC2 155 | MSMEG_0425 | - | 3e-53 | 42.21% (289) | putative membrane protein DcsA |
| M. thermoresistible (build 8) | TH_2104 | - | 6e-05 | 26.11% (226) | sulfate permease |
| M. ulcerans Agy99 | MUL_1212 | - | 5e-05 | 26.94% (193) | transmembrane protein |
| M. vanbaalenii PYR-1 | Mvan_3572 | cobS | 6e-07 | 30.26% (228) | cobalamin synthase |
CLUSTAL 2.0.9 multiple sequence alignment
MMAR_0549|M.marinum_M -MSGTVMPIVRVAILADSRLTEVALPAELPLREILPAVQRLVIPVAEDGD
MUL_1212|M.ulcerans_Agy99 -MSGTVMPIVRVAILADSRLTEVALPAELPLREILPAVQRLVIPVAEDGD
MAV_4863|M.avium_104 MTSGTVMPIVRVAILADSRLTEMALPAELPLREILPAVQRLVVPAAANGD
MAB_0811|M.abscessus_ATCC_1997 --------------MQAG-------TPSLS--------------------
MSMEG_0425|M.smegmatis_MC2_155 --------------MSDESSATALLSPALSR-------------------
Mvan_3572|M.vanbaalenii_PYR-1 --------------------------------------------------
TH_2104|M.thermoresistible__bu --VIATAKENLIRLLPSRRDYAELPRSWRRDILAGITVGVVALPLALAFG
Mflv_0017|M.gilvum_PYR-GCK --------------MRSERQPMIVDPRATP--------------------
MMAR_0549|M.marinum_M -------AGSADLGIAGHLSLAPVGGAPFSLDASLDTVGVVDGDLLVLQP
MUL_1212|M.ulcerans_Agy99 -------AGSADLGIAGHLSLAPVGGAPFSLDASLDTVGVVDGDLLVLQP
MAV_4863|M.avium_104 SEDGAPSRGAAEVGGAVQLSLAPIGGAPFSLDASLDTVGVVDGDLLALQP
MAB_0811|M.abscessus_ATCC_1997 ----------------KGTGLAALGVLSFSLSFPATAWALEG-----FGP
MSMEG_0425|M.smegmatis_MC2_155 ----------------AGLGWGFLGVAAFSFTVIFTRVALGG-----LSP
Mvan_3572|M.vanbaalenii_PYR-1 ------------------MISSLTGAFAFATVLPTPTR------------
TH_2104|M.thermoresistible__bu ISSGVGAAAGLITAVVAGLVAAVFGGSHIQVSGPTGAMAVILAPIVAQHG
Mflv_0017|M.gilvum_PYR-GCK -----------------DSVPPVAGGALLAVAVVLAALNLRPAVTSIATL
* :
MMAR_0549|M.marinum_M VPTGPAAPGIVEDIADAA-------------------MIFSTSRLRPWDA
MUL_1212|M.ulcerans_Agy99 VPTGPAAPGIVEDIADAA-------------------MIFSTSRLRPWDA
MAV_4863|M.avium_104 VPAGPAAPGIVEDIADAA-------------------MIFSTSRLRPWGT
MAB_0811|M.abscessus_ATCC_1997 WSATGIRGAVAAALALIA-------------------LGVARSPLP----
MSMEG_0425|M.smegmatis_MC2_155 LFIGAGRAVVAAALAAAA-------------------LTFTRAALP----
Mvan_3572|M.vanbaalenii_PYR-1 ------ATAMVGRGVLTA-------------------LPVAGAALG----
TH_2104|M.thermoresistible__bu LTSIALVTVLAGLIVLAAGITGLGRAVTFIPWPVIEGFTLGIAAIIFLQQ
Mflv_0017|M.gilvum_PYR-GCK LHDIRGDLAVSATWAGLVTTLP--------------ALCFAGAGLAAP--
: . . : . : :
MMAR_0549|M.marinum_M RHLQRGALAALIGVALAGSGLAVAYRAATGALAGLLIVSVIAVAMALAG-
MUL_1212|M.ulcerans_Agy99 RHLQRGALAALIGVALAGSGLAVAYRVATGALAGLLIVSVIAVAMALAG-
MAV_4863|M.avium_104 THIQRFALATVIAVALLATGLSVSYRVATGALAGLVAVSAVAALTAIVG-
MAB_0811|M.abscessus_ATCC_1997 ----------------ARSDWGALAVVAIGCAVGFPLLTTLALQTSST--
MSMEG_0425|M.smegmatis_MC2_155 ----------------RGRQWLRLGVVAAGVVAGFPLLTSYALTTVPA--
Mvan_3572|M.vanbaalenii_PYR-1 ---------------VLAAGVLWAGSWAFGDGSALAGVLTVAVLLLAT--
TH_2104|M.thermoresistible__bu VPAAFATEAPAGQRTLVAAWHVVTHADWTAAVKTLSVVSLVALLMVVLPR
Mflv_0017|M.gilvum_PYR-GCK -------------WVASRIGLSRAISVALLALTAGLALRGVGGEYVVIG-
: .
MMAR_0549|M.marinum_M ------------LLLGARSPRTGIALSIAALAPVGAALALAVPGSFGAAQ
MUL_1212|M.ulcerans_Agy99 ------------LLLGARSPRTGIALSIAALAPVGAALALAVPGSFGAAQ
MAV_4863|M.avium_104 ------------LLATARSPRNGMALSIAALVPIGAALALAVPGRFGPAQ
MAB_0811|M.abscessus_ATCC_1997 ----------------------AHSAVVIGALPMATAAIAAVRTGARHSG
MSMEG_0425|M.smegmatis_MC2_155 ----------------------THGAVVIALLPAATAVAAVLRCREHPPL
Mvan_3572|M.vanbaalenii_PYR-1 -----------------------RGLHIDGLS--DTVDALGCYGPPERAL
TH_2104|M.thermoresistible__bu LHRSIPESLTAVVAATVIVTVFGISVATIGELPSQLPTPVLPQADMGAMQ
Mflv_0017|M.gilvum_PYR-GCK ----------------ATLIACAGIALANVLIPVVIKTSFPARIGMMTGI
MMAR_0549|M.marinum_M VLLAAAGVTAWSLICLMVPGE---QRERIVALFTAVAVVGAALLLAAGAE
MUL_1212|M.ulcerans_Agy99 VLLAAAGVTAWSLICLMVPGE---QRERIVALFTAVAVVGAALLLAAGVE
MAV_4863|M.avium_104 VMLAAAGVTAWSLIALMAPSA---ERERLAGFFTATAVLGAAVLLAAGAE
MAB_0811|M.abscessus_ATCC_1997 TFWAAASVGAATVIVFTLAQN--HGRPTLADLYLFAALLVCAAGYAEGGR
MSMEG_0425|M.smegmatis_MC2_155 AFWAAAGAGALAAVVFAMLHGGGVGQLHWADLLLFGAVIAAAIGYAEGGL
Mvan_3572|M.vanbaalenii_PYR-1 AVMRDGTAGPFGVAAVAA------------------TLLVQSLAFAQSG-
TH_2104|M.thermoresistible__bu TLLGAALAIAALAAIESLLSARVAATMSATGPYHPDRELVGQGMASVASG
Mflv_0017|M.gilvum_PYR-GCK YTAALQGGGALGSAVTPGLADPLGGWRTALMVWAAVSLLALTLWIPATAR
. : .
MMAR_0549|M.marinum_M LLWQLPVS------------SIGCGLIVAALLVTIQAAQLSAVWARFPLP
MUL_1212|M.ulcerans_Agy99 LLWQLPVS------------SIGCGLIVAALLVTIQAAQLSAVWARFPLP
MAV_4863|M.avium_104 LLWHITPV------------ALGCGLIVAALLVTVEAAPLSALWARFPLP
MAB_0811|M.abscessus_ATCC_1997 LSARMPG------------------------------------WQVIAWG
MSMEG_0425|M.smegmatis_MC2_155 LARELGS------------------------------------WQTVSWA
Mvan_3572|M.vanbaalenii_PYR-1 -------------------------------------------WAAVFIA
TH_2104|M.thermoresistible__bu LFGGMPATGAIARTAVNVRSGARTRLAAIVHSLVLLAVVYLATGPVSAIP
Mflv_0017|M.gilvum_PYR-GCK HRSAWAVHTR------------------------PSAARRSLLRSPLAWT
MMAR_0549|M.marinum_M VIPAPGDPTPSAPSLRVLEDLPRRVRVSDAHQSGFIAAAVLLSVLGSVAI
MUL_1212|M.ulcerans_Agy99 VIPAPGDPTPSAPSLRVLEDLPRRVRVSDAHQSGFIAAAVLLSVLGSVAI
MAV_4863|M.avium_104 VIPAPGDPTPSAPPLPVLEDLPRRVRIGDAHQSGFIAAAVLLSALGSVAI
MAB_0811|M.abscessus_ATCC_1997 VVLAA--PVNLLVTVLALPHEPVHLNAHALIGMAYLAAISQFGGF-----
MSMEG_0425|M.smegmatis_MC2_155 LVVAA--PVMVALTAAAVVDRPPQAGAGEWAAFGYLAAVSMFLGF-----
Mvan_3572|M.vanbaalenii_PYR-1 VVAGR---------VAVVAACRRGVPAAAGSTLGALVSGTQPRWVA----
TH_2104|M.thermoresistible__bu LSALAGVLMVTSFRMVSLHTARRILRSTRSDALTFVLTALVTITFDLIEA
Mflv_0017|M.gilvum_PYR-GCK VTVFFGSQAFLAYIMMGWLPQVFIDNGIDKVQAGLLVAVASLVGVPLSLV
: : : .
MMAR_0549|M.marinum_M ALR----------------------------PDTVSALGWYVVAATAATA
MUL_1212|M.ulcerans_Agy99 ALR----------------------------PDTVSALGWYVVAATAATA
MAV_4863|M.avium_104 ALR----------------------------PETLSAAGWYVVGATAATS
MAB_0811|M.abscessus_ATCC_1997 -------------------------------------VVWYRGMGFIG--
MSMEG_0425|M.smegmatis_MC2_155 -------------------------------------FAWYRGLAIGP--
Mvan_3572|M.vanbaalenii_PYR-1 -------------------------------------AGWTVAVAAAAVP
TH_2104|M.thermoresistible__bu VQIGVLVAAFFALRNVARRSGVTREELPGEPQPGDERIALLRLEGSMFFG
Mflv_0017|M.gilvum_PYR-GCK ITP--------------------------LAARSASQSGWIVGVGSFGFL
.
MMAR_0549|M.marinum_M TLRARIWDSAACKAWLLTQPYLVGGTLLVLYAATGHFIAAFGALVVLAVL
MUL_1212|M.ulcerans_Agy99 TLRARIWDSAACKAWLLTQPYLVGGTLLVLYAATGHFIAAFGALVVLAVL
MAV_4863|M.avium_104 VLRARVWDSAACKAWLLAQPYLAAGVLLVLYTATGRYAGALGAVLVLLAL
MAB_0811|M.abscessus_ATCC_1997 --------VARASQLQLAQPLLTLIWAVLLLDERFSPAVPLTAAVVFTCI
MSMEG_0425|M.smegmatis_MC2_155 --------MAQVSQVQLVQPVLTICWAALLLHESLTWTTACGGAAVVASA
Mvan_3572|M.vanbaalenii_PYR-1 --------VCARPWQGPLVVALALACSAGLVAHCVRRFGGITGDVLGAAL
TH_2104|M.thermoresistible__bu VAERMSSTISEIEADDISVVIIRLSQLGTLDATGANSLAQIATELERRGI
Mflv_0017|M.gilvum_PYR-GCK G-------TVGLMVAPTAQPLLWSVLLGTGLSGFSLALALLGLRARTPED
:
MMAR_0549|M.marinum_M AVAWVVVALNPVIASPESYSLPLRRLLGFLAAGLDASLIPVMAYLVGLFT
MUL_1212|M.ulcerans_Agy99 AVAWVVVALNPVIASPESYSLPLRRLLGFLAAGLDASLIPVMAYLAGLFT
MAV_4863|M.avium_104 VAVWIVVALNPGIAAPESYSLPVRRLVGFVATGLDASLIPVMAFVVGLFG
MAB_0811|M.abscessus_ATCC_1997 VITQRART------------------------------------------
MSMEG_0425|M.smegmatis_MC2_155 GFAVRMRRSPRANSHAGT--------------------------------
Mvan_3572|M.vanbaalenii_PYR-1 EVTTTIAAVGLAVR------------------------------------
TH_2104|M.thermoresistible__bu TVIIKGVQPEHSKLLSNVGVFESLRHEKHLIDSLEDAIEHARSHVARQQT
Mflv_0017|M.gilvum_PYR-GCK TAALSGMAQGFGYLLAGTGPFLFGLLHDVTHGWTAPWVLFLAVFCVQTVT
MMAR_0549|M.marinum_M WVLNR-----
MUL_1212|M.ulcerans_Agy99 WVLNR-----
MAV_4863|M.avium_104 WVLDR-----
MAB_0811|M.abscessus_ATCC_1997 ----------
MSMEG_0425|M.smegmatis_MC2_155 ----------
Mvan_3572|M.vanbaalenii_PYR-1 ----------
TH_2104|M.thermoresistible__bu ARTTS-----
Mflv_0017|M.gilvum_PYR-GCK GALAGRNRYV