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MPALLGSAALGFTGLAFLLPVAPMWAVHIGADNLGAGLVNTVLMACTVVAQLLVGRLIRRVGMRVTLAIG LLLLGGPALLHLFAETLWAVLVLAALRGLGFGILTVSGVDGVAGLFAQEHRGRAVGAYGLAIAAPQFIFT PLAPWLAEQAGFGLVFALATAPVLAIPFALAFTRPVPTPPRRDDDEKFALTAGLVSPIVALVVITASGGA ILTFAPQFGSAEAAFASLLALTGLTALARWLVGGLADRFGPARFIQPLLYLGAVGLATVATGIARGALIA EILIVVGAALVGIAYGALQNVTLVQAFAATGEHARSKVSVAWNVGFDGGTGIGALAVGALATSGSFPMAF AVLAAACAVMGVASYFAHRRTV
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. smegmatis MC2 155 | MSMEG_0264 | - | - | 100% (372) | transmembrane transport protein |
| M. smegmatis MC2 155 | MSMEG_2137 | - | 5e-15 | 26.56% (369) | permease of the major facilitator superfamily protein |
| M. smegmatis MC2 155 | MSMEG_2810 | - | 1e-10 | 28.65% (384) | major facilitator superfamily protein |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb3018 | - | 3e-07 | 23.36% (381) | integral membrane protein |
| M. gilvum PYR-GCK | Mflv_1475 | - | 2e-19 | 28.57% (378) | major facilitator transporter |
| M. tuberculosis H37Rv | Rv1877 | - | 4e-08 | 23.77% (366) | integral membrane protein |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | MAB_3449c | - | 6e-15 | 26.25% (381) | putative transporter |
| M. marinum M | MMAR_0690 | - | 3e-13 | 25.00% (380) | putative transport protein |
| M. avium 104 | MAV_3974 | - | 2e-08 | 24.34% (378) | permease of the major facilitator superfamily protein |
| M. thermoresistible (build 8) | TH_2039 | - | 3e-10 | 24.53% (371) | PROBABLE CONSERVED INTEGRAL MEMBRANE PROTEIN |
| M. ulcerans Agy99 | MUL_4170 | - | 9e-10 | 27.54% (334) | integral membrane transport protein |
| M. vanbaalenii PYR-1 | Mvan_1951 | - | 1e-14 | 25.54% (372) | major facilitator superfamily transporter |
CLUSTAL 2.0.9 multiple sequence alignment
MAV_3974|M.avium_104 -----------------------------------------------MVA
Mvan_1951|M.vanbaalenii_PYR-1 MTSHTEGECPGADARSNSGTADAKSSSQSATKQPLPREVWVLVAANFVVA
MAB_3449c|M.abscessus_ATCC_199 MSSCREGN-----------------ADNATVKPRLPWEIWVLVVASLVIA
Mb3018|M.bovis_AF2122/97 -------------------------MSRDPTGVGARWAIMIVSLGVTASS
TH_2039|M.thermoresistible__bu -------------------------MPVSSISPARRWSMLVIALAATLFS
MMAR_0690|M.marinum_M -----------------------------MTDSSRRVVLAAVGFTFFIDM
Mflv_1475|M.gilvum_PYR-GCK ------------------------------MAPLSPTAQRAPLLAAGFTT
MUL_4170|M.ulcerans_Agy99 ---------------------------MNRGNVRPKLVLGVIVLGSFIAS
Rv1877|M.tuberculosis_H37Rv ----------MAGPTAPTTAPTAIRAGGPLLSPVRRNIIFTALVFGVLVA
MSMEG_0264|M.smegmatis_MC2_155 ---------------------------------------MPALLGSAALG
MAV_3974|M.avium_104 LGYG-VISPALPTFARSFGVSIKAVTFLVTVFSLSRLCFAPISGLLTERL
Mvan_1951|M.vanbaalenii_PYR-1 LGYG-VVAPVLPQYARHFGVSISAATFVITAFAVMRLVGAPPAGMLVQRL
MAB_3449c|M.abscessus_ATCC_199 LGFG-VVAPALPQYARSFGVSVTAATAVVSSFAAFRLVFAPVAGALVQRL
Mb3018|M.bovis_AF2122/97 FLFINGVAFLIPRLENARGTPLSHAGLLASMPSWGLVVTMFAWGYLLDHV
TH_2039|M.thermoresistible__bu VVFINGVAFVIPTLHREHGLSLAQAGLLSALPSFGMVATLIAWGYLVDRI
MMAR_0690|M.marinum_M LVYG-IVVPVLPRLAKPAGLEFLGVGVVFACYGLAYFVLTPVAGWLIDRR
Mflv_1475|M.gilvum_PYR-GCK AFGAHAVAGTLGTTTTGTAASLLTLGAMLAIYDGAEVILKPLFGTLADRI
MUL_4170|M.ulcerans_Agy99 IDLT-IVNVALPTLSRALQASNAELQWIVDSYAIAAAGLLLAAGNLGDRY
Rv1877|M.tuberculosis_H37Rv ATGQTIVVPALPTIVAELGSTVDQS-WAVTSYLLGGTVVVVVAGKLGDLL
MSMEG_0264|M.smegmatis_MC2_155 FTGLAFLLPVAPMWAVHIGADNLGAGLVNTVLMACTVVAQLLVGRLIRRV
: * *
MAV_3974|M.avium_104 GERRIYIGGLLIVAVSTAACAFSQAYWQLMLCRVFSGVGSTMFYVSALGL
Mvan_1951|M.vanbaalenii_PYR-1 GERRVYISGLIIVALSTAACAFAETYWQLLLFRSLGGIGSAMFTVSSLGL
MAB_3449c|M.abscessus_ATCC_199 GERWVYMSGLLIVAASTGICAFVHSYWQLLVFRSVGGVGSTMFTVSAAAL
Mb3018|M.bovis_AF2122/97 GERMVMAVGSALTAAAAYAAASVHSLLWIGVFLFLGGMAAGGCNSAGGRL
TH_2039|M.thermoresistible__bu GERIVLTVGSALTAASAFAAAAVDSLLLVGVFLLLGGMAAASSNTASARV
MMAR_0690|M.marinum_M GSRSVFLSGAIILMLATLAFGYASSPVGLVTCRVLQGGAAAATWVAGYAT
Mflv_1475|M.gilvum_PYR-GCK GARTVLIAGLAVFAVASLSFAVADETAWLWAARLGQGIGAAAFSPAASAL
MUL_4170|M.ulcerans_Agy99 GRRGWLTIGLVIVGASSAVAASAGSAQAVIGARAVMGVGAAIIFPTSLAL
Rv1877|M.tuberculosis_H37Rv GRNRVLLGSVVVFVVGSVLCGLSQTMTMLAISRALQGVGAGAISVTAYAL
MSMEG_0264|M.smegmatis_MC2_155 GMRVTLAIGLLLLGGPALLHLFAETLWAVLVLAALRGLGFGILTVSGVDG
* . . : : : * . :.
MAV_3974|M.avium_104 MIHISPA-DARGRIAGLFTTSFMVGAVGGPAVG-GLAAGWGLTAPFVVYG
Mvan_1951|M.vanbaalenii_PYR-1 MIRISPP-DARGRVAGLFSSGFMVGSVGGPILG-ALTAGFGLSAPFLIYG
MAB_3449c|M.abscessus_ATCC_199 LVRIAPE-EIRGRAQGLYGSSFLLGMVAGPALG-SAVVGLSLSAPFIIYA
Mb3018|M.bovis_AF2122/97 VSGWFPP-QQRGLAMGIRQTAQPLGIASGALVIPELAER-GVHAGLMFPA
TH_2039|M.thermoresistible__bu VVGWFPP-HQRGLVMGIRQTAQPLGVALGALVIPRLAQSHGISAALLFPA
MMAR_0690|M.marinum_M LVEIFPR-EQRGRAVGLASIGTALGALLGPALGGLAYEASGPHAPFLGAA
Mflv_1475|M.gilvum_PYR-GCK VARLAPA-SGQGRAFGTYGSYKSVGYTLGPLIGGAIVTFGGLQALFAVMA
MUL_4170|M.ulcerans_Agy99 VTNVFVDSTHRARAIGVWSAVTGIAVVIGPILGGWLIEHFSVGSVFWVNV
Rv1877|M.tuberculosis_H37Rv AAEVVPL-RDRGRYQGVLGAVFGVNTVTGPLLGGWLTDYLSWRWAFWINV
MSMEG_0264|M.smegmatis_MC2_155 VAGLFAQ-EHRGRAVGAYGLAIAAPQFIFTPLAPWLAEQAGFGLVFALAT
:. * . : . :
MAV_3974|M.avium_104 VAMLGVALVLFLGLRNSALAAPPPP-TRSTVT------------------
Mvan_1951|M.vanbaalenii_PYR-1 AALLVAATVVFVSLRHSTVVGQQDEDPEEPVP------------------
MAB_3449c|M.abscessus_ATCC_199 AALVIVVMLVYFGLRRSTLLDVADEHHGTPVR------------------
Mb3018|M.bovis_AF2122/97 VVCTLAAVASVLGIVDPPRKSRTKASEQELA-------------------
TH_2039|M.thermoresistible__bu AVCAVAAVICLIGVLDPPRPPRASADGRHPQ-------------------
MMAR_0690|M.marinum_M GLSALAVAALAASLPQAAGGQASGPGMWSGE-------------------
Mflv_1475|M.gilvum_PYR-GCK ALAAAVAVWAAVAVPRLAVLPRTRQTLLDTVR------------------
MUL_4170|M.ulcerans_Agy99 PIAVVAIVSVNMFVPTSRNPDRPPLDLPGLLVSTVGVTVLTYTLIET-PN
Rv1877|M.tuberculosis_H37Rv PVSIAVLTVAATAVPALARPPKPVIDYLGILVIAVATTALIMATSWGGTT
MSMEG_0264|M.smegmatis_MC2_155 APVLAIPFALAFTRPVPTPPRRDDDEKFALTAG-----------------
MAV_3974|M.avium_104 --MREALRVRAYQSALLSNFATGWSAFGLRMALVPLFVSDVMGRGIG---
Mvan_1951|M.vanbaalenii_PYR-1 --FRTVFRHRAYRAALFSNFATGWASFGLRIALVPLFIVEVLGQSPG---
MAB_3449c|M.abscessus_ATCC_199 --LTSALRHRTFLAALMSNFSAGWAIFGIRGALLPLLVVEALHQRPG---
Mb3018|M.bovis_AF2122/97 ----SPYRGSSILWRIHAASALLMMPQTVTVTFMLVWLINHHGWSVA---
TH_2039|M.thermoresistible__bu ----NPYRGSGLLWRIHAVSVLLVVPQGVIWTFTLVWLMTERSWSAG---
MMAR_0690|M.marinum_M ----RAFPGLAVPWLVAGLAVG--LALGAVEATLPIDLVARFDASGV---
Mflv_1475|M.gilvum_PYR-GCK --RFSESSFVTPTLALAAATAALSAGVGFLPVLG-----TDFGLSPV---
MUL_4170|M.ulcerans_Agy99 IGWASARTAAGFALAVVLLAVFLWLERRTWHPILDLSIFANRRFSGGTAA
Rv1877|M.tuberculosis_H37Rv YAWGSATIVGLLIGAAVALGFFVWLEGRAAAAILPPRLFGSPVFAVCCVL
MSMEG_0264|M.smegmatis_MC2_155 ------------LVSPIVALVVITASGGAILTFAPQFGSAEAAFASL---
MAV_3974|M.avium_104 ----------------------------TIGVVLAAFAGGNALAVVPSGY
Mvan_1951|M.vanbaalenii_PYR-1 ----------------------------AAGLALTAFAVGNISVVIPSGH
MAB_3449c|M.abscessus_ATCC_199 ----------------------------AAGLVFAAFAAGDVSTAFLAGS
Mb3018|M.bovis_AF2122/97 ----------------------------QAGVLVTISQLLGALGRVAVGR
TH_2039|M.thermoresistible__bu ----------------------------SAGTMVMIAQVLGAGGRVAAGR
MMAR_0690|M.marinum_M ----------------------------TVGLLFALTTVAFIVTSQYAGR
Mflv_1475|M.gilvum_PYR-GCK ----------------------------VTGAVVSVLALTTAVVQPLAGR
MUL_4170|M.ulcerans_Agy99 VTTAYLVMCGFIFVATQYLQFVAAYRAFDTGVRLVPLAFSYAGLSVIAPR
Rv1877|M.tuberculosis_H37Rv SFVVGFAMLGALTFVPIYLGYVDGASATASGLRTLPMVIGLLIASTGTGV
MSMEG_0264|M.smegmatis_MC2_155 ----------------------------------LALTGLTALARWLVGG
MAV_3974|M.avium_104 LSDRMGR--RTLLIVGLVTSGAATVWLG-FVASLPVFLVAAGVVGVVTGI
Mvan_1951|M.vanbaalenii_PYR-1 LSDRLGR--RKLMIFGLTLAAASTALVG-FTTSLPVFLVAAYIAGAATGI
MAB_3449c|M.abscessus_ATCC_199 WSDDIGR--KPLVVAGLVVCGSTVVAMG-FVSSLPVLVVLSLIGGIGAGL
Mb3018|M.bovis_AF2122/97 WSDHVGSRMRPVRLIAAAAAATLFLLAA-VDNEGSRYDVLLMIAISVIAV
TH_2039|M.thermoresistible__bu WSDLVGSRLRPIRTIALAAAAAMALLAL-TDALDSPVSVAFMVIAAVVTV
MMAR_0690|M.marinum_M LSDAGRR--APVLAAGWVTLGVALAVMG-VPSAVGIQAAALVLLGAGLGA
Mflv_1475|M.gilvum_PYR-GCK AADSGRISLTSGLFTGVVVTAAGVAAAA-LPGLVG-LLGGAVVIGVGCGL
MUL_4170|M.ulcerans_Agy99 IVERVGT--TAVVTSGLVMVAVSVACAGGFDAGTPYWLIAAVMAALGSGL
Rv1877|M.tuberculosis_H37Rv LVGRTGR-YKIFPVAGMALMAVAFLLMSQMDEWTPPLLQSLYLVVLGAGI
MSMEG_0264|M.smegmatis_MC2_155 LADRFGPARFIQPLLYLGAVGLATVATG-IARGALIAEILIVVGAALVGI
. :
MAV_3974|M.avium_104 YMSPLQAAVADILGNEA---RAGLPVATVQMMSDLGAIVGSMAVG-----
Mvan_1951|M.vanbaalenii_PYR-1 FVSPQQAAVADVVGNKS---RGGTAVATFQMMADFGSIGGSLLVG-----
MAB_3449c|M.abscessus_ATCC_199 YASPQQAAVADVVGSRG---RAGTALATFQMTSDIGLVVGPVVAG-----
Mb3018|M.bovis_AF2122/97 LDNGLEATAITEYAGPY---WSGRALGIQNTTQRLMAAAGPPLFG-----
TH_2039|M.thermoresistible__bu SDNSLAFTAIAEIAGPY---WTGRALGTQNTSQLLTTAITPPLFG-----
MMAR_0690|M.marinum_M MIATIMPALADAMESAGGAQRPGTAAAAYNLAFSAGTVAGGPLAG-----
Mflv_1475|M.gilvum_PYR-GCK ITPLAFTMLARSTPEER----LGQTMGAAEIGRECGDAAGPLVVA-----
MUL_4170|M.ulcerans_Agy99 GLTMAPASEAIMGSLSP--TAAGVGSAVTGVARQLGACLGVAIVGSVFAS
Rv1877|M.tuberculosis_H37Rv GLSMQVLVLIVQNTSSF--EDLGVATSGVTFFRVVGASFGTATFGALFVN
MSMEG_0264|M.smegmatis_MC2_155 AYGALQNVTLVQAFAATGEHARSKVSVAWNVGFDGGTGIGALAVG-----
. .
MAV_3974|M.avium_104 -------------------WAAEQIGYGWGFFISGVVLLIAAVGWVMAPE
Mvan_1951|M.vanbaalenii_PYR-1 -------------------LIAQYTSFGWAFLISGVILAVAAVGWIFAPE
MAB_3449c|M.abscessus_ATCC_199 -------------------AIAEHTSYGWAFVVGGAMPLIAAVAWVFAPE
Mb3018|M.bovis_AF2122/97 -------------------SLITTAAYPTAWALCGVFPLAAVPLVPVRLL
TH_2039|M.thermoresistible__bu -------------------GLIGVAGYPVAFALCAVLPLAAVPLVPADPA
MMAR_0690|M.marinum_M -------------------WMADLRSFQDAAMLIAVVTLTCGVLAALVHA
Mflv_1475|M.gilvum_PYR-GCK -------------------AIAAASTVPFGFLGLAAVVAASGVGVRRGRG
MUL_4170|M.ulcerans_Agy99 VYLRSMSSNAALHGLDPAARAAMRQSMAAAKQVLDQLPVGEAPAIRHAVE
Rv1877|M.tuberculosis_H37Rv FLDRRLG--------SALTSGAVPVPAVPSPAVLHQLPQSMAAPIVRAYA
MSMEG_0264|M.smegmatis_MC2_155 -------------------ALATSGSFPMAFAVLAAACAVMGVASYFAHR
.
MAV_3974|M.avium_104 TR--------------------TATELEADLMAASRTSSRCEQQL-----
Mvan_1951|M.vanbaalenii_PYR-1 TR--------------------PRASTEHTQARPLGPEAGGEVP------
MAB_3449c|M.abscessus_ATCC_199 TLG-------------------RLASPQVRSMQEVAEDVGGPER------
Mb3018|M.bovis_AF2122/97 PPGLETRARRQSVRRHRWWQAVRCHAWPNGPRRPGPPGQPRRVRQGGTAI
TH_2039|M.thermoresistible__bu TP----------------------------QIRPSSPESPRRVR------
MMAR_0690|M.marinum_M AV-----------------------------VRRAVSDA-----------
Mflv_1475|M.gilvum_PYR-GCK RVG----------------------------------GVG----------
MUL_4170|M.ulcerans_Agy99 SAFLESFGVGCLACAVFAAVGAVVVAFLLPARGEVRDDVAVSVAASAIGP
Rv1877|M.tuberculosis_H37Rv ESLTQVFLCAVSVTVVGFILALLLREVPLTDIHDDADDLGDGFGVPRAES
MSMEG_0264|M.smegmatis_MC2_155 RTV-----------------------------------------------
MAV_3974|M.avium_104 --------------------------------------------------
Mvan_1951|M.vanbaalenii_PYR-1 --------------------------------------------------
MAB_3449c|M.abscessus_ATCC_199 --------------------------------------------------
Mb3018|M.bovis_AF2122/97 TPPT----------------------------------------------
TH_2039|M.thermoresistible__bu --------------------------------------------------
MMAR_0690|M.marinum_M --------------------------------------------------
Mflv_1475|M.gilvum_PYR-GCK --------------------------------------------------
MUL_4170|M.ulcerans_Agy99 AEGGK---------------------------------------------
Rv1877|M.tuberculosis_H37Rv PEDVLEIAVRRMLPNGVRLRDIATQPGCGLGVAELWALLRIYQYQRLFEA
MSMEG_0264|M.smegmatis_MC2_155 --------------------------------------------------
MAV_3974|M.avium_104 --------------------------------------------------
Mvan_1951|M.vanbaalenii_PYR-1 --------------------------------------------------
MAB_3449c|M.abscessus_ATCC_199 --------------------------------------------------
Mb3018|M.bovis_AF2122/97 --------------------------------------------------
TH_2039|M.thermoresistible__bu --------------------------------------------------
MMAR_0690|M.marinum_M --------------------------------------------------
Mflv_1475|M.gilvum_PYR-GCK --------------------------------------------------
MUL_4170|M.ulcerans_Agy99 --------------------------------------------------
Rv1877|M.tuberculosis_H37Rv VRLTDIGRHLHVPYQVFEPVFDRLVQTGYAARDGDILTLTPSGHRQVDSL
MSMEG_0264|M.smegmatis_MC2_155 --------------------------------------------------
MAV_3974|M.avium_104 --------------------------------------------------
Mvan_1951|M.vanbaalenii_PYR-1 --------------------------------------------------
MAB_3449c|M.abscessus_ATCC_199 --------------------------------------------------
Mb3018|M.bovis_AF2122/97 --------------------------------------------------
TH_2039|M.thermoresistible__bu --------------------------------------------------
MMAR_0690|M.marinum_M --------------------------------------------------
Mflv_1475|M.gilvum_PYR-GCK --------------------------------------------------
MUL_4170|M.ulcerans_Agy99 --------------------------------------------------
Rv1877|M.tuberculosis_H37Rv AVLIRQWLLDHLAVAPGLKRQPDHQFEAALQHVTDAVLVQRDWYEDLGDL
MSMEG_0264|M.smegmatis_MC2_155 --------------------------------------------------
MAV_3974|M.avium_104 ----------
Mvan_1951|M.vanbaalenii_PYR-1 ----------
MAB_3449c|M.abscessus_ATCC_199 ----------
Mb3018|M.bovis_AF2122/97 ----------
TH_2039|M.thermoresistible__bu ----------
MMAR_0690|M.marinum_M ----------
Mflv_1475|M.gilvum_PYR-GCK ----------
MUL_4170|M.ulcerans_Agy99 ----------
Rv1877|M.tuberculosis_H37Rv SESRQLAATT
MSMEG_0264|M.smegmatis_MC2_155 ----------